| Page Contents: Abstract |
Sakurai, Shunsuke, Nagano, Seido, (2012)
' A molecular network underlying spontaneous camp oscillation and synchronization in dictyostelium. '
Journal of theoretical biology
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| Abstract:We propose a molecular network, incorporating both adaptation and phosphorylation, to account for the spontaneous cAMP oscillation of Dictyostelium discoideum. We have modified the scheme previously proposed by Loomis and his collaborators so as to include adaptation by the cAMP receptor and such that extracellular cAMP is formed by the secreted intracellular cAMP instead of being directly produced by adenylyl cyclase. Furthermore, it was confirmed that our scheme could be also applied to spontaneous cAMP production by a cluster of cells. | |||||||
| Status: | aheadofprint | Type: | Journal article | Source: | PUBMED | PubMed ID: | 22588019 |
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