To view more details, including parent strains and references, click on the gene name link.
To view all mutants sharing a phenotype, click on that phenotype.
| Gene Name |
Synonyms |
Gene Products |
dictyBaseID |
Phenotypes |
| arkA | ARCK-1 | GRAM domain-containing protein, PKC domain-containing protein, PE/DAG binding, ankyrin repeat-containing protein, tyrosine kinase-like (TKL) protein | DDB0229363 | aberrant morphology |
| cak1 | CK1, DdCK1 | casein kinase I (CK1), protein serine/threonine kinase | DDB0185182 | abolished growth on bacterial plates, decreased sensitivity to DNA-damaging agents |
| canA | CNA, PP2B | CaM-dependent protein phosphatase, catalytic subunit, calcineurin A, protein phosphatase 2B, protein serine/threonine phosphatase | DDB0185021 | delayed development in the presence of gossypol, impaired cAMP signaling in the presence of gossypol, no known phenotype, reduced growth rate in the presence of gossypol |
| cbpC | CBP3 | calcium-binding protein | DDB0191405 | delayed culmination, precocious aggregation, reduced aggregate size, reduced slug migration, small fruiting bodies |
| cdk5 | crp, crpA | cyclin-dependent kinase | DDB0191155 | delayed aggregation, increased aggregate size, increased level of extracellular counting factor component(s), increased level of intracellular counting factor component(s), reduced growth in suspension, reduced level of extracellular counting factor component(s), reduced number of spores, reduced phagocytosis, reduced pinocytosis |
| cdk8 | CDK, Ddcdk8 | CTD kinase, cyclin-dependent kinase | DDB0191261 | no known phenotype |
| ChLim | | LIM domain-containing protein, calponin homology (CH) domain-containing protein | DDB0231986 | increased basal level of F-actin, reduced growth rate on bacterial plates, reduced phagocytosis |
| cofA | DCOF1 | cofilin | DDB0214987 | increased actin bundle formation, increased cell motility, increased membrane ruffling |
| crlA | | G protein coupled receptor, cAMP receptor-like protein | DDB0215007 | abolished growth in axenic medium |
| cupB | | calcium up-regulated protein, ricin B lectin domain-containing protein | DDB0191376 | aggregation defective |
| cycB | clb1 | G2/M-specific cyclinB, cyclin | DDB0185035 | cell cycle arrest |
| dagA | CRAC, synag7 | PH domain-containing protein, cytosolic regulator of adenylate cyclase, cytosolic regulator of adenylyl cyclase | DDB0191434 | no known phenotype |
| dgkA | MHC-PKC, MHCK | diacylglycerol kinase protein | DDB0185037 | development arrests at loose aggregate stage, reduced chemotaxis rate, increased cell motility |
| dia1 | DIA-1 | Differentiation associate-1. | DDB0191142 | delayed aggregation |
| forH | dDia2, drf2 | actin-binding protein, formin homology domain-containing protein | DDB0231180 | increased cell spreading, increased filopodium formation, reduced cell motility |
| fpaA | FP21, SKP1, fpa1 | cytosolic glycoprotein FP21, ubiquitin ligase subunit SKP1 | DDB0191107 | aberrant fruiting bodies |
| fpaB | FP21, SKP1, fpa2 | cytosolic glycoprotein FP21, ubiquitin ligase subunit SKP1 | DDB0185043 | aberrant fruiting bodies |
| fszA | FtsZ | mitochondrial cell division protein | DDB0219983 | increased mitochondrial tubule formation |
| gbfA | GBF | G-box binding factor, transcription factor | DDB0191361 | precocious expression of prespore-specific genes |
| gpaA | Ga1, Galpha1 | G-protein subunit alpha 1 | DDB0191255 | aberrant cytokinesis, aberrant development |
| gpaD | Ga4, Galpha4 | G-protein subunit alpha 4 | DDB0216411 | aberrant fruiting bodies, reduced number of spores |
| gpaE | Ga5, Galpha5 | G-protein subunit alpha 5 | DDB0191246 | precocious expression of post-aggregative genes, precocious tip formation |
| gpaG | Ga7, Galpha7 | G-protein subunit alpha 7 | DDB0185045 | aberrant fruiting bodies |
| gpaH | Ga8, Galpha8 | G-protein subunit alpha 8 | DDB0219991 | no known phenotype |
| limE | DdLim, crp | LIM domain-containing protein | DDB0214939 | aberrant cytokinesis |
| limF | | LIM domain-containing protein | DDB0231985 | increased basal level of F-actin, increased phagocytosis |
| mhcA | MHC | myosin II heavy chain, myosin heavy chain | DDB0191444 | increased filopodium formation, reduced filopodium formation |
| mhkA | MHCK-A | alpha kinase, myosin heavy chain kinase, protein serine/threonine kinase | DDB0216274 | aberrant cytokinesis, development arrests at mound stage, reduced growth in suspension, increased cell motility |
| mhkB | MHCK-B | alpha kinase, myosin heavy chain kinase, protein serine/threonine kinase | DDB0191333 | aberrant cytokinesis, increased cell motility |
| mkkA | MEKKalpha | MEK kinase, STE11 family protein kinase, protein serine/threonine kinase | DDB0220118 | aberrant fruiting bodies, delayed development, development arrests at mound stage |
| mtaA | CP224, DdCP224 | centrosomal protein CP224 | DDB0189914 | aberrant cytokinesis, aberrant microtubule cytoskeleton organization, increased number of microtubule-organizing centers |
| nek2 | Ddnek2 | Nek (NimA-related) family protein kinase, protein serine/threonine kinase | DDB0216282 | aberrant nuclear morphology, increased number of microtubule-organizing centers |
| numA | cmbA, numA1, numA2, numB | calmodulin-binding protein, nucleomorphin | DDB0191501 | aberrant cytokinesis, abolished nuclear localization |
| pakA | DPAKa, dpak1 | STE20 family protein kinase, p21-activated protein kinase, protein serine/threonine kinase | DDB0191313 | aggregation defective, delayed development, development arrests at mound stage |
| pakB | Ddpak, mihck | PAK sub-family kinase, myosin I heavy chain kinase, myosin heavy chain kinase | DDB0191345 | abolished cytokinesis, increased phagocytosis, increased pinocytosis |
| pakC | | PH domain-containing protein, STE20 family protein kinase, p21-activated protein kinase, pleckstrin homology (PH) domain-containing protein, putative protein serine/threonine kinase | DDB0202066 | decreased lateral pseudopod supression, reduced cell motility, reduced chemotaxis rate |
| pats1 | | putative protein serine/threonine kinase, putative protein tyrosine kinase, putative tyrosine kinase-like (TKL) protein | DDB0191503 | aberrant cytokinesis |
| pldB | | phospholipase D1 (PLD1) | DDB0231507 | aggregation defective |
| pteN | ptenA | 3-phosphatidylinositol 3-phosphatase, PI3 phosphatase PTEN homolog | DDB0191093 | reduced cell motility |
| ptpA1 | PTP1 | Protein-tyrosine phosphatase 1 | DDB0185117 | aberrant fruiting bodies, aggregation defective |
| rab21 | rabB | Rab GTPase | DDB0191253 | reduced phagocytosis |
| rab8A | sas1, sasA | Rab GTPase | DDB0214885 | aberrant cytoskeleton organisation, aggregation defective, increased aggregate size, increased cell-cell adhesion, no known phenotype, small fruiting bodies |
| rab8B | sas2, sasB | Rab GTPase | DDB0185216 | increased aggregate size |
| rapA | rap1 | Ras GTPase | DDB0216229 | increased accumulation of cGMP |
| rasB | | Ras GTPase | DDB0201661 | aberrant cytokinesis, reduced growth in suspension |
| rckA | rck1 | RGS domain-containing protein, tyrosine kinase-like (TKL) protein | DDB0214828 | delayed aggregation, development arrests at mound stage, reduced chemotaxis rate |
| rzpA | rZIP | RING/leucine zipper protein | DDB0191162 | increased expression of prestalk cell markers, reduced expression of prespore cell markers |
| sgkA | SK, SPHK | sphingosine kinase | DDB0185181 | aberrant cytokinesis, increased resistance to carboplatin,increased resistance to cisplatin |
| sgkB | SK, SPHK | sphingosine kinase | DDB0220131 | increased resistance to carboplatin,increased resistance to cisplatin |
| smlA | | unknown | DDB0191525 | increased level of intracellular counting factor component(s) |
| spkA | SAPKalpha | SAM domain-containing protein, ankyrin repeat-containing protein, stress-activated MEK-like kinase, tyrosine kinase-like (TKL) protein | DDB0185206 | aberrant morphology, increased basal level of F-actin, reduced cell polarity, reduced chemotaxis rate |
| trap1 | Dd-trap1 | TNF receptor-associated protein | DDB0185036 | development arrests at loose aggregate stage, precocious aggregation |
| vasP | | VASP, vasodilator-stimulated phosphoprotein | DDB0229340 | increased actin bundle formation, increased basal level of F-actin, increased filopodium formation |
| vwkA | | VWFA domain-containing protein, alpha kinase, protein serine/threonine kinase | DDB0216405 | aberrant cytokinesis, development arrests at mound stage, increased level of myosin protein, increased myosin II assembly, reduced growth in suspension |
| yakA | dagB | CMGC family protein kinase, DYRK family protein kinase, protein serine/threonine kinase | DDB0191191 | abolished growth in axenic medium |
