To view more details, including parent strains and references, click on the gene name link.
To view all mutants sharing a phenotype, click on that phenotype.
| Gene Name |
Synonyms |
Gene Products |
dictyBaseID |
Phenotypes |
Type |
|
abpA | | actin bundling protein, alpha actinin | DDB0191133 | aberrant development | Multiple |
| abpC | ABP-120, ABP120, GHR | FLN, actin binding protein, ddFLN, filamin, gelation factor | DDB0201554 | aberrant development | Multiple |
| abpD | | actin binding protein, interaptin | DDB0191136 | aberrant development, delayed development, reduced spore viability | Null |
| acaA | ACA | adenylate cyclase, adenylyl cyclase | DDB0214814 | aggregation defective | Null |
| acbA | | acyl-CoA binding protein | DDB0231469 | reduced spore viability | Null |
| acgA | ACG | adenylate cyclase, adenylyl cyclase, non-G-protein-coupled adenylyl cyclase | DDB0185013 | precocious spore germination | Null |
| acrA | ACR, DG1100 | adenylate cyclase, adenylyl cyclase | DDB0191294 | defective spore differentiation, long stalks, spores inviable | Null |
| alrA | | aldehyde reductase, aldo-keto reductase | DDB0215363 | increased aggregate size, reduced level of cytosolic glucose, reduced level of extracellular counting factor component(s) | Null |
| alxA | ALIX, DdAlix, alx | ALG-2 interacting protein X | DDB0185177 | aberrant fruiting bodies, aberrant morphology, abolished spore cell differentiation, development arrests at loose aggregate stage, reduced sorting to prestalk region | Null |
| alxA | ALIX, DdAlix, alx | ALG-2 interacting protein X | DDB0185177 | delayed development | Other |
| amdA | | AMP deaminase | DDB0191089 | aberrant fruiting bodies, increased number of pstA cells, reduced number of spores | Null |
| amiB | | unknown | DDB0214900 | abolished down-regulation of growth phase genes, aggregation defective, defective in activation of adenylate cyclase (ACA), reduced expression of aggregation genes | Null |
| ampA | D11, pegA | adhesion modulation protein A, prestalk D11 protein precursor | DDB0185088 | aberrant localization of prespore markers, delayed development, delayed tip formation, increased cell-cell adhesion, increased substrate adhesion, precocious expression of prespore-specific genes, reduced number of prestalk cells | Null |
| amtC | | ammonium transport protein C, ammonium transporter | DDB0191130 | aberrant morphology, delayed culmination, development arrests at slug stage | Null |
| apm1 | | clathrin-adaptor medium chain apm1, mu1, μ1 | DDB0191102 | delayed development, reduced spore germination ability | Null |
| arkA | ARCK-1 | GRAM domain-containing protein, PKC domain-containing protein, PE/DAG binding, ankyrin repeat-containing protein, tyrosine kinase-like (TKL) protein | DDB0229363 | aberrant fruiting bodies | Null |
| arkA | ARCK-1 | GRAM domain-containing protein, PKC domain-containing protein, PE/DAG binding, ankyrin repeat-containing protein, tyrosine kinase-like (TKL) protein | DDB0229363 | large sori, short stalks | Multiple |
| arkA | ARCK-1 | GRAM domain-containing protein, PKC domain-containing protein, PE/DAG binding, ankyrin repeat-containing protein, tyrosine kinase-like (TKL) protein | DDB0229363 | aberrant morphology | OE |
| atg1 | APG1 | ULK (Unc51-like kinase) family protein kinase, autophagy protein 1, protein serine/threonine kinase | DDB0185178 | aggregation defective, , defective spore differentiation, | Null |
| atg5 | APG5 | autophagy protein 5 | DDB0191390 | defective spore differentiation, multiple tips | Null |
| atg6 | APG6 | autophagy protein 6 | DDB0191425 | defective spore differentiation, multiple tips, short stalks, small fruiting bodies | Null |
| atg7 | APG7 | autophagy protein 7 | DDB0214819 | defective spore differentiation, multiple tips | Null |
| atg8 | APG8 | autophagy protein 8 | DDB0191413 | defective spore differentiation, multiple tips, small fruiting bodies | Null |
|
cadA | CAD1, DdCAD-1, GP24,
rcdD, veg102 | calcium-dependent cell adhesion molecule-1, glycoprotein gp24 | DDB0191175 | delayed culmination, increased number of prestalk cells, reduced number of spores | Null |
| capB | | CABP1-related protein, CABP1-related protein, splice variant | DDB0185023 | delayed development | Null |
| canA | CNA, PP2B | CaM-dependent protein phosphatase, catalytic subunit, calcineurin A, protein phosphatase 2B, protein serine/threonine phosphatase | DDB0185021 | delayed development in the presence of gossypol, impaired cAMP signaling in the presence of gossypol, no known phenotype, reduced growth rate in the presence of gossypol | OE |
| carA | cAR1 | G-protein-coupled receptor, cAMP receptor | DDB0185024 | aggregation defective, defective in activation of adenylate cyclase (ACA), reduced chemoattractant-mediated F-actin polymerization | Multiple |
| carB | cAR2 | G-protein-coupled receptor, cAMP receptor | DDB0191393 | development arrests at mound stage | Null |
| carC | cAR3 | G-protein-coupled receptor, cAMP receptor | DDB0216181 | aggregation defective, defective in activation of adenylate cyclase (ACA), reduced chemoattractant-mediated F-actin polymerization | Multiple |
| carD | cAR4 | G-protein-coupled receptor, cAMP receptor | DDB0216256 | aberrant fruiting bodies, delayed culmination, increased expression of prespore cell markers, increased expression of prestalk cell markers | Null |
| catB | | catalase B | DDB0191496 | delayed development, spores hypersensitive to H2O2 (peroxide) | Null |
| cbfA | CMBF, cbf | C-module-binding factor | DDB0216196 | aggregation defective | Other |
| cbpA | CBP1 | calcium-binding protein | DDB0185026 | delayed aggregation, increased aggregate size | Null |
| cbpC | CBP3 | calcium-binding protein | DDB0191405 | delayed culmination, precocious aggregation, reduced aggregate size, reduced slug migration, small fruiting bodies | OE |
| cbpC | CBP3 | calcium-binding protein | DDB0191405 | increased slug migration | Other |
| cdk5 | crp, crpA | cyclin-dependent kinase | DDB0191155 | delayed aggregation, increased aggregate size, increased level of extracellular counting factor component(s), increased level of intracellular counting factor component(s), reduced level of extracellular counting factor component(s), reduced number of spores, | OE |
| cdk8 | CDK, Ddcdk8 | CTD kinase, cyclin-dependent kinase | DDB0191261 | aberrant localization of prestalk markers, aggregation defective, multiple tips, reduced expression of aggregation genes, reduced expression of spore genes, spores inviable | Null |
| CF45-1 | | component of the counting factor (CF) complex | DDB0191161 | increased aggregate size, increased cell-cell adhesion, increased level of cytosolic glucose, reduced aggregate size | Null |
| CF50 | | component of the counting factor (CF) complex | DDB0185090 | increased aggregate size, increased cell-cell adhesion, increased expression of prespore cell markers, reduced level of extracellular counting factor component(s) | Null |
| chcA | | clathrin heavy chain | DDB0185029 | aberrant fruiting bodies, aberrant localization of prestalk markers, defective spore differentiation, delayed aggregation | Null |
| chcA | | clathrin heavy chain | DDB0185029 | aggregation defective, defective in formation of coated vesicles, | Other |
| clcA | | clathrin light chain | DDB0191305 | multiple tips | Null |
| cmfA | CMF | Conditioned medium factor, density sensing factor | DDB0191097 | aggregation defective | Null |
| cmfB | CMFR1 | putative CMF receptor CMFR1 | DDB0191095 | aggregation defective, reduced expression of prespore cell markers | Null |
| comB | DG1016, ORF1016 | Rab GTPase domain-containing protein | DDB0214836 | culmination defective | Null |
| comD | | Transport protein. | DDB0191430 | culmination defective | Null |
| comE | | FNIP repeat-containing protein, ankyrin repeat-containing protein | DDB0220032 | aberrant fruiting bodies | Null |
| comF | | ComF (Fragment). | DDB0214838 | aggregation defective | Null |
| comG | ALDH | aldehyde dehydrogenase, putative NAD-dependent aldehyde dehydrogenase | DDB0185188 | multiple tips | Null |
| comH | | putative GATA-binding transcription factor | DDB0214839 | development arrests at mound stage | Null |
| cotA | SP96 | spore coat protein sp96 | DDB0185032 | aberrant spore coat morphology | Null |
| cotB | SP70 | spore coat protein SP70 | DDB0185091 | aberrant spore coat morphology | Null |
| cotC | SP60 | spore coat protein SP60 | DDB0185189 | aberrant spore coat morphology | Null |
| cpyA | DG1104 | WD-40 repeat-containing protein | DDB0191244 | aberrant fruiting bodies | Null |
| CRTF | | transcription factor | DDB0216392 | aggregation defective, defective spore differentiation, reduced expression of aggregation genes | Null |
| csbA | | 12 kDa protein | DDB0185034 | aggregation defective | Other |
| csbB | | 12 kDa protein | DDB0185093 | aggregation defective | Other |
| csbC | | 12 kDa protein | DDB0220655 | aggregation defective | Other |
| cshA | | citrate synthase | DDB0191110 | development arrests at loose aggregate stage, development hypersensitive to ammonia, | Null |
| ctnA | countin | component of the counting factor (CF) complex, countin | DDB0185089 | increased GTP-gamma-S-stimulated guanylyl cyclase (GC) activity, increased aggregate size, increased cAMP-induced cGMP pulse, increased cell-cell adhesion, increased level of cytosolic glucose, reduced basal level of F-actin, reduced cAMP-induced cAMP pulse, reduced level of ABP120 protein | Null |
| ctnB | countin2 | countin2 | DDB0214993 | increased number of aggregates, small fruiting bodies | Null |
| ctrA | DG1058 | putative cationic amino acid transporter | DDB0185190 | aberrant fruiting bodies | Null |
| cudA | | O00841 Putative transcriptional regulator cudA. | DDB0191385 | abolished stalk formation, defective spore differentiation | Null |
| culA | | cullin | DDB0185191 | development arrests at tipped mound stage, multiple tips | Null |
| culB | | homolog of cullin | DDB0191260 | multiple tips | Null |
| cupB | | calcium up-regulated protein, ricin B lectin domain-containing protein | DDB0191376 | aggregation defective | OE |
| dagA | CRAC, synag7 | PH domain-containing protein, cytosolic regulator of adenylate cyclase, cytosolic regulator of adenylyl cyclase | DDB0191434 | abolished post-aggregative gene expression, aggregation defective, defective in activation of adenylate cyclase (ACA), reduced expression of aggregation genes | Null |
| dcsA | | UDP-glucose:1, 4-beta-D-glucan 4-beta-D-glucosyltransferase, cellulose synthase | DDB0191159 | aberrant spore coat morphology, abolished stalk formation, defective spore differentiation | Null |
| DD3-3 | | unknown | DDB0231683 | precocious aggregation | Null |
| DG1003 | ORF1003 | unknown | DDB0220111 | culmination defective | Null |
| DG1007 | ORF1007 | unknown | DDB0191322 | culmination defective | Null |
| DG1037 | ORF1037 | ubiquitin domain-containing protein | DDB0191301 | aberrant fruiting bodies | Null |
| DG1041 | ORF1041 | unknown | DDB0191328 | culmination defective | Null |
| DG1054 | | unknown | DDB0219980 | aberrant fruiting bodies | Null |
| DG1060 | ORF1060 | putative tyrosine phosphatase | DDB0218345 | aberrant fruiting bodies | Null |
| DG1062 | | unknown | DDB0191143 | aberrant fruiting bodies | Null |
| DG1074 | | RNA-binding region RNP-1 domain-containing protein | DDB0220129 | aberrant fruiting bodies | Null |
| DG1091 | | TPR repeat-containing protein, tetratrico peptide repeat-containing protein | DDB0191302 | aberrant fruiting bodies | Null |
| DG1094 | | RhoGAP domain-containing protein | DDB0191387 | aberrant fruiting bodies | Null |
| DG1098 | | unknown | DDB0220119 | aberrant fruiting bodies | Null |
| DG1105 | | unknown | DDB0220018 | aberrant fruiting bodies | Null |
| DG1106 | | Kelch repeat-containing protein, RING Zn finger-containing protein | DDB0185081 | aberrant fruiting bodies | Null |
| DG1110 | | unknown | DDB0191339 | aberrant fruiting bodies | Null |
| DG1112 | | Rho GTPase activation domain-containing protein | DDB0185082 | aberrant fruiting bodies | Null |
| DG1113 | | C2 domain-containing protein | DDB0220019 | aberrant fruiting bodies | Null |
| DG1118 | | Snf7-family protein | DDB0191317 | aberrant fruiting bodies | Null |
| DG1124 | | calcium-binding EF-hand domain-containing protein | DDB0185095 | aberrant fruiting bodies | Null |
| DG1122 | | E set domain-containing protein | DDB0220029 | aberrant fruiting bodies | Null |
| DG2033 | | tRNA/rRNA methyltransferase SpoU family protein | DDB0220033 | aberrant fruiting bodies | Null |
| dgkA | MHC-PKC, MHCK | diacylglycerol kinase protein | DDB0185037 | aberrant development, increased myosin II assembly, reduced chemotaxis rate, reduced spore viability | Null |
| dgkA | MHC-PKC, MHCK | diacylglycerol kinase protein | DDB0185037 | development arrests at loose aggregate stage, reduced chemotaxis rate | OE |
| dhkA | | histidine kinase | DDB0215354 | long stalks, reduced number of spores | Null |
| dhkB | | histidine kinase | DDB0215358 | precocious spore germination | Null |
| dhkC | | histidine kinase | DDB0185038 | insensitive to ammonia, precocious development | Null |
| dia1 | DIA-1 | Differentiation associate-1. | DDB0191142 | precocious aggregation | Other |
| dia1 | DIA-1 | Differentiation associate-1. | DDB0191142 | delayed aggregation | OE |
| dia2 | DIA-2 | Differentiation associate-2. | DDB0185193 | development arrests at mound stage | Other |
| dimA | | putative basic-leucine zipper (bZIP) transcription factor | DDB0216189 | aberrant fruiting bodies, abolished prestalk cell differentiation in response to DIF-1, increased number of prespore cells, long fingers, reduced number of prestalk cells, reduced prestalk O cell differentiation, thin fingers | Null |
| dmtA | | des-methyl-DIF-1 methyltransferase | DDB0219945 | aberrant fruiting bodies, abolished DIF-1 production, abolished prestalk O cell differentation, reduced number of prestalk cells | Null |
| docA | DG1012, DG2016, timA | DOCK family protein, SH3 domain-containing protein, putative guanine nucleotide exchange factor (GEF) | DDB0201649 | aberrant fruiting bodies | Null |
| dokA | | histidine kinase | DDB0185194 | aberrant development | Null |
| dpoA | | prolyl oligopeptidase | DDB0185041 | development is resistant to Li+ | Null |
| dstA | Dd-STATa, STATa | STAT, signal transducer and activator of transcription (STAT) family protein | DDB0215388 | aberrant localization of prestalk markers, defective stalk cell differentiation, delayed aggregation, increased expression of prestalk cell markers, increased expression of prestalk cell markers | Null |
| dstC | Dd-STATc, STATc | signal transducer and activator of transcription (STAT) family protein, transcriptional repressor | DDB0215378 | aberrant localization of prestalk markers, precocious development, precocious expression of post-aggregative genes | Null |
| dtfA | | cell surface protein DTFA | DDB0191273 | aberrant fruiting bodies, delayed tip formation | Null |
|
ecmA | pDd63 | extracellular matrix protein ST430 | DDB0220137 | long fingers, thin fingers, weak slime trail | Null |
| erkB | dagC, erk2 | MAP kinase, extracellular response kinase, mitogen-activated protein kinase (MAPK), protein serine/threonine kinase | DDB0191457 | aggregation defective | Null |
| erkB | dagC, erk2 | MAP kinase, extracellular response kinase, mitogen-activated protein kinase (MAPK), protein serine/threonine kinase | DDB0191457 | aggregation defective | Multiple |
| fbxA | chtA | F-Box A protein, cheaterA | DDB0185042 | aberrant fruiting bodies, development arrests at slug stage, increased number of prespore cells | Null |
| fcpA | DG1148, fcp1 | putative CTD phosphatase | DDB0229894 | aberrant fruiting bodies | Null |
| forC | | formin homology domain-containing protein | DDB0191362 | aberrant fruiting bodies, abolished slug migration | Null |
| fpaA | FP21, SKP1, fpa1 | cytosolic glycoprotein FP21, ubiquitin ligase subunit SKP1 | DDB0191107 | aberrant fruiting bodies | OE |
| fpaB | FP21, SKP1, fpa2 | cytosolic glycoprotein FP21, ubiquitin ligase subunit SKP1 | DDB0185043 | aberrant fruiting bodies | OE |
| gbfA | GBF | G-box binding factor, transcription factor | DDB0191361 | abolished post-aggregative gene expression, development arrests at mound stage | Null |
| gbfA | GBF | G-box binding factor, transcription factor | DDB0191361 | precocious expression of prespore-specific genes | OE |
| gdt1 | gdtA | putative transmembrane protein, tyrosine kinase-like (TKL) protein | DDB0215003 | aggregation defective, increased level of discoidin | Multiple |
| gbqA | DG1120 | G-protein alpha subunit family protein, guanine nucleotide binding protein | DDB0215001 | aberrant fruiting bodies | Null |
| gdt1 | gdtA | putative transmembrane protein, tyrosine kinase-like (TKL) protein | DDB0215003 | increased level of discoidin, precocious aggregation | Null |
| gdt2 | | putative transmembrane protein, tyrosine kinase-like (TKL) protein | DDB0220631 | increased level of discoidin, precocious aggregation | Null |
| gefA | RasGEFA, aimless, aleA | Ras guanine nucleotide exchange factor, RasGEF | DDB0191187 | aggregation defective, defective in activation of adenylate cyclase (ACA), defective in cAMP-dependent activation of guanylyl cyclase (GC), reduced chemotaxis rate | Null |
| gefB | RasGEFB | Ras guanine nucleotide exchange factor, RasGEF | DDB0191498 | delayed aggregation, increased basal level of F-actin, reduced aggregate size, reduced rates of endocytosis | Null |
| ggtA | | UDP-glucose glycoprotein alpha-glucosyltransferase, glycosyltransferase | DDB0220030 | aberrant fruiting bodies | Null |
| GP138A | fusA | cell surface glycoprotein gp138 | DDB0219938 | reduced expression of prespore cell markers | Multiple |
| GP138B | fusB | cell surface glycoprotein gp138 | DDB0191447 | reduced expression of prespore cell markers | Multiple |
| GP138C | fusD | cell surface glycoprotein gp138 | DDB0201648 | reduced expression of prespore cell markers | Multiple |
| GP138D | fusC | DdFRP1alpha | DDB0191539 | reduced expression of prespore cell markers | Multiple |
| gpaA | Ga1, Galpha1 | G-protein subunit alpha 1 | DDB0191255 | long stalks, increased expression of prestalk cell markers | Null |
| gpaA | Ga1, Galpha1 | G-protein subunit alpha 1 | DDB0191255 | aberrant development | OE |
| gpaB | Ga2, Galpha2 | G-protein subunit alpha 2 | DDB0191327 | aggregation defective, defective in activation of adenylate cyclase (ACA), defective in cAMP-dependent activation of guanylyl cyclase (GC), reduced cAMP-induced cAMP pulse, reduced cAMP-induced cGMP pulse | Null |
| gpaB | Ga2, Galpha2 | G-protein subunit alpha 2 | DDB0191327 | aggregation defective, reduced cAMP-induced cAMP pulse, reduced cAMP-induced cGMP pulse, reduced chemotaxis rate | Other |
| gpaB | Ga2, Galpha2 | G-protein subunit alpha 2 | DDB0191327 | aggregation defective, increased level of discoidin | Multiple |
| gpaC | Ga3, Galpha3 | G-protein subunit alpha 3 | DDB0216258 | aggregation defective, defective in activation of adenylate cyclase (ACA), increased PKA (protein kinase A) activity, reduced expression of aggregation genes | Null |
| gpaD | Ga4, Galpha4 | G-protein subunit alpha 4 | DDB0216411 | aberrant fruiting bodies, reduced expression of prespore cell markers, reduced number of spores | Null |
| gpaD | Ga4, Galpha4 | G-protein subunit alpha 4 | DDB0216411 | aberrant fruiting bodies, reduced number of spores | OE |
| gpaE | Ga5, Galpha5 | G-protein subunit alpha 5 | DDB0191246 | delayed post-aggregative gene expression, delayed tip formation | Null |
| gpaE | Ga5, Galpha5 | G-protein subunit alpha 5 | DDB0191246 | precocious expression of post-aggregative genes, precocious tip formation | OE |
| gpaG | Ga7, Galpha7 | G-protein subunit alpha 7 | DDB0185045 | aberrant fruiting bodies | OE |
| gpa9 | Ga9, Galpha9 | G-protein subunit alpha 9 | DDB0230128 | increased number of aggregates, reduced aggregate size | Null |
| gpa9 | Ga9, Galpha9 | G-protein subunit alpha 9 | DDB0230128 | increased aggregate size, reduced number of aggregates | Other |
| gpbA | Gbeta, Gb | G protein b-subunit, G-protein subunit beta | DDB0185046 | aggregation defective | Null |
| gnt2 | cis4c, gntB, modB | GlcNAc transferase, glycosyltransferase | DDB0185186 | increased number of prestalk cells,increased resistance to cisplatin | Null |
| gskA | GSK-3, GSK3 | CMGC family protein kinase, glycogen synthase kinase 3, protein serine/threonine kinase | DDB0185150 | aberrant fruiting bodies, aberrant spore head morphology, increased number of prestalk cells, reduced number of spores, reduced slug migration, short stalks | Null |
| hbx2 | hbx-2 | homeodomain (HOX) containing protein, putative homeobox transcription factor | DDB0185105 | development arrests at mound stage, increased basal disc size, increased number of pstO cells, reduced number of prespore cells | Multiple |
| helC | | DEAD-box RNA helicase | DDB0215338 | aberrant fruiting bodies, aggregation defective | Null |
| helE | | helicase | DDB0215339 | aberrant fruiting bodies | Null |
| ifkA | | GCN2 family protein kinase, eukaryotic translation initiation factor 2 alpha (eIF2alpha) kinase | DDB0185218 | increased aggregate size, precocious aggregation, precocious expression of aggregation genes, reduced level of extracellular counting factor component(s) | Null |
| iplA | | inositol 1, 4, 5-trisphosphate receptor-like protein | DDB0201571 | abolished cAMP-induced Ca2+ influx, delayed aggregation, reduced aggregate size | Null |
| lagC | GP150 | cell adhesion molecule, signal protein | DDB0214927 | development arrests at loose aggregate stage | Null |
| limB | lim2, paxA | LIM domain-containing protein | DDB0191245 | development arrests at mound stage | Null |
| lipA | ALOX, DG1006 | lipoxygenase, putative arachidonate 12-lipoxygenase | DDB0214940 | culmination defective | Null |
| lipB | DG1056 | similar to aminoalcoholphosphotransferase | DDB0191335 | aberrant fruiting bodies | Null |
| manA | | alpha-mannosidase | DDB0201569 | aggregation defective | Other |
| mekA | DdMEK1, mek1 | MAP kinase kinase (MAP2K), STE7 family protein kinase | DDB0191164 | reduced aggregate size | Null |
| mhcA | MHC | myosin II heavy chain, myosin heavy chain | DDB0191444 | development arrests at mound stage, increased F-actin polymerization | Null |
| mhkA | MHCK-A | alpha kinase, myosin heavy chain kinase, protein serine/threonine kinase | DDB0216274 | development arrests at mound stage, reduced sorting to prestalk region | OE |
| mkkA | MEKKalpha | MEK kinase, STE11 family protein kinase, protein serine/threonine kinase | DDB0220118 | aberrant fruiting bodies, delayed development, development arrests at mound stage | OE |
| mkcA | | PAK sub-family kinase, STE20 family protein kinase, protein serine/threonine kinase | DDB0191179 | partial suppression of tagB mutation | Multiple |
| migA | DG1020 | BTB/POZ domain-containing protein, coagulation factor 5/8 type C-terminal domain-containing protein | DDB0191409 | aberrant fruiting bodies, abolished slug migration, small fruiting bodies | Null |
| mkcB | DG1101 | putative STE20 family protein kinase, putative protein serine/threonine kinase | DDB0191334 | aberrant fruiting bodies | Null |
| mkkA | MEKKalpha | MEK kinase, STE11 family protein kinase, protein serine/threonine kinase | DDB0220118 | long stalks, precocious development, small sori | Null |
| mlcE | EMLC | essential myosin light chain (ELC) | DDB0214813 | aberrant development, aberrant localization of prespore markers, delayed aggregation | Null |
| mlcR | RMLC | Regulatory myosin light chain (RLC) | DDB0185146 | aberrant myosin II organization, development arrests at mound stage | Null |
| modA | DG1033 | alpha-glucosidase II | DDB0191113 | aberrant fruiting bodies | Null |
| mybB | Ddmyb2, myb2 | myb-related protein, putative myb transcription factor | DDB0215356 | aggregation defective, defective in activation of adenylate cyclase (ACA), reduced cAMP-induced cAMP pulse, reduced cAMP-induced cGMP pulse, reduced expression of aggregation genes | Null |
| mybC | | myb transcription factor | DDB0214816 | culmination defective, reduced SDF-1 production, reduced SDF-2 production | Null |
| myoA | DMIA, abmA | myosin IA heavy chain | DDB0215392 | delayed aggregation, reduced chemotaxis rate | Null |
| myoA | DMIA, abmA | myosin IA heavy chain | DDB0215392 | small fruiting bodies | Multiple |
| myoB | DMIB, abmB | myosin IB | DDB0191351 | small fruiting bodies | Multiple |
| myoC | DMIC, abmC | myosin IC | DDB0215355 | small fruiting bodies | Multiple |
| myoI | | class VII unconventional myosin | DDB0185049 | reduced spore germination ability | Null |
| nosA | | U box domain-containing protein, ubiquitin-protein ligase (E3) | DDB0216192 | development arrests at mound stage | Null |
| osbA | | oxysterol binding protein | DDB0214942 | culmination defective | Null |
| pakA | DPAKa, dpak1 | STE20 family protein kinase, p21-activated protein kinase, protein serine/threonine kinase | DDB0191313 | delayed development, no known phenotype | Null |
| pakA | DPAKa, dpak1 | STE20 family protein kinase, p21-activated protein kinase, protein serine/threonine kinase | DDB0191313 | aggregation defective, delayed development, development arrests at mound stage | OE |
| pdeD | gbpA, pde5 | beta-lactamase domain-containing protein, cGMP-specific phosphodiesterase, cGMP-stimulated cGMP phosphodiesterase | DDB0185054 | delayed cAMP-induced Ca2+ influx, reduced Ca2+-induced Ca2+ influx, reduced cAMP-induced Ca2+ influx | Null |
| pdsA | PDE, pde1, pdeA | cAMP phosphodiesterase, cyclic nucleotide phosphodiesterase | DDB0219974 | aggregation defective | Null |
| phdA | DG1093 | PH domain-containing protein | DDB0191446 | reduced aggregate size, reduced basal level of F-actin, reduced chemotaxis rate, small fruiting bodies | Null |
| piaA | DG1117, Pianissimo, amiA | cytosolic regulator of adenylate cyclase, cytosolic regulator of adenylyl cyclase | DDB0185055 | aggregation defective, defective in activation of adenylate cyclase (ACA) | Null |
| pikA | PI3K, PI3K1, PIK1 | PI3kinase, phosphatidylinositol-4, 5-diphosphate 3-kinase | DDB0214949 | delayed aggregation, inviable, multiple tips | Multiple |
| pikB | PI3K2, PIK2 | PI3kinase, phosphatidylinositol-4, 5-diphosphate 3-kinase | DDB0191474 | delayed aggregation, inviable, multiple tips | Multiple |
| pkaC | DdPK2, DdPK3, PK2, PK3,
PKA, PKA-C, cAK, pkacat | AGC family protein kinase, PKA (protein kinase A) catalytic subunit, cAMP-dependent protein kinase, protein serine/threonine kinase | DDB0215408 | aberrant fruiting bodies | Null |
| pkaC | DdPK2, DdPK3, PK2, PK3,
PKA, PKA-C, cAK, pkacat | AGC family protein kinase, PKA (protein kinase A) catalytic subunit, cAMP-dependent protein kinase, protein serine/threonine kinase | DDB0215408 | aggregation defective, increased level of discoidin | Multiple |
| pkbA | Akt, AktPKB, DK1, PKB, pkfC | AGC family protein kinase, Akt/PKB family kinase, rac-alpha serine/threonine protein kinase | DDB0191195 | aggregation defective, reduced sorting to prestalk region | Multiple |
| pkaR | PKA, cAK, rdeC | protein kinase A regulatory subunit | DDB0214950 | aberrant fruiting bodies, precocious development, precocious spore differentiation | Null |
| PIPkinA | Ddpik6, PIK6 | phosphatidylinositol phosphate kinase 6, putative phosphatidylinositol-4-phosphate 5-kinase | DDB0185056 | aggregation defective, reduced expression of aggregation genes | Null |
| pkgB | DK2, PK2, PKBR1, pkfA | AGC family protein kinase, Akt/PKB family kinase, protein kinase 2, protein serine/threonine kinase | DDB0191365 | development arrests at mound stage | Null |
| pkgB | DK2, PK2, PKBR1, pkfA | AGC family protein kinase, Akt/PKB family kinase, protein kinase 2, protein serine/threonine kinase | DDB0191365 | aggregation defective, reduced sorting to prestalk region | Multiple |
| pldB | | phospholipase D1 (PLD1) | DDB0231507 | precocious aggregation | Null |
| pldB | | phospholipase D1 (PLD1) | DDB0231507 | aggregation defective | OE |
| plbG | DG1067, PLB | phospholipase B-like | DDB0220116 | aberrant fruiting bodies | Null |
| PLIP | | phosphatidylinositol phosphatase | DDB0185057 | delayed aggregation | Null |
| ponA | | ponticulin | DDB0215380 | aberrant development, delayed development | Null |
| potA | DG1057 | Similar to Y51A2D.19.p. | DDB0214952 | aggregation defective | Null |
| ppiA | rcdR, veg159 | cyclophilin, peptidyl-prolyl isomerase | DDB0216173 | long stalks | Other |
| ppkA | DdPPK1, PPK, PPK1 | poly P kinase, polyphosphate kinase | DDB0216190 | delayed culmination, , reduced number of spores | Null |
| proA | | profilin I | DDB0191178 | development arrests at slug stage, increased basal level of F-actin | Multiple |
| proB | | profilin II | DDB0191249 | no known phenotype | Null |
| proB | | profilin II | DDB0191249 | development arrests at slug stage, increased basal level of F-actin | Multiple |
| prtC | DG1026 | 20S proteasome subunit C2, proteasome alpha-subunit | DDB0214956 | delayed culmination, long stalks | Null |
| ptpA1 | PTP1 | Protein-tyrosine phosphatase 1 | DDB0185117 | increased number of pstO cells, precocious development, reduced number of prespore cells | Null |
| ptpA1 | PTP1 | Protein-tyrosine phosphatase 1 | DDB0185117 | aberrant fruiting bodies, aggregation defective | OE |
| ptpB | DdPTPa | phosphotyrosine phosphatase ptp2, protein tyrosine phosphatase | DDB0214985 | increased slug size | Null |
| ptpC | PTP3 | phosphotyrosine phosphatase ptp3, protein tyrosine phosphatase | DDB0214986 | increased aggregate size | Null |
| pslA | | PslA. | DDB0191506 | defective spore differentiation, increased aggregate size | Null |
| psiA | | prespore-cell-inducing factor, psi factor | DDB0201657 | abolished prespore cell division | Null |
| pufA | | RNA binding protein | DDB0218189 | aberrant fruiting bodies, culmination defective, precocious development | Null |
| pykA | | pyridoxal kinase | DDB0191114 | aggregation defective | Null |
| qkgA | roco2 | putative protein serine/threonine kinase, putative protein tyrosine kinase, putative tyrosine kinase-like (TKL) protein | DDB0185215 | delayed aggregation, increased aggregate size, increased growth rate | Null |
|
rab8A | sas1, sasA | Rab GTPase | DDB0214885 | aggregation defective, increased aggregate size, increased cell-cell adhesion, no known phenotype, small fruiting bodies | OE |
| rab8B | sas2, sasB | Rab GTPase | DDB0185216 | increased aggregate size | OE |
| rasC | | Ras GTPase | DDB0214827 | aggregation defective, increased cell size, reduced basal level of F-actin, reduced chemoattractant-mediated F-actin polymerization, reduced phosphorylation of PkbA (Akt/PKB) | Null |
| rasC | | Ras GTPase | DDB0214827 | aggregation defective | Multiple |
| rasD | Dd-ras, Ddras, ras, rasA | Ras GTPase | DDB0216195 | aggregation defective | Multiple |
| rasD | Dd-ras, Ddras, ras, rasA | Ras GTPase | DDB0216195 | development arrests at tipped mound stage, multiple tips | Other |
| rckA | rck1 | RGS domain-containing protein, tyrosine kinase-like (TKL) protein | DDB0214828 | delayed slug formation, increased aggregate size, increased chemotaxis rate, precocious aggregation | Null |
| rckA | rck1 | RGS domain-containing protein, tyrosine kinase-like (TKL) protein | DDB0214828 | delayed aggregation, development arrests at mound stage, reduced chemotaxis rate | OE |
| rdeA | | RDEA. | DDB0191140 | aberrant fruiting bodies, precocious aggregation, precocious development, precocious expression of aggregation genes, reduced aggregate size | Null |
| redA | | sulfite reductase (NADPH) | DDB0215407 | aberrant mound color | Null |
| regA | DG1030, pde2 | cAMP phosphodiesterase | DDB0191479 | aberrant fruiting bodies, increased resistance to cisplatin, precocious spore differentiation, reduced number of spores, reduced spore germination ability | Null |
| regA | DG1030, pde2 | cAMP phosphodiesterase | DDB0191479 | aggregation defective | Multiple |
| rgaA | DGAP1, RIP2,
rasGAP, rasGAP1 | RasGTPase-activating protein | DDB0191437 | culmination defective, defective spore differentiation, defective stalk cell differentiation | Null |
| ripA | RIP3 | ras interacting protein | DDB0201626 | aggregation defective, defective in activation of adenylate cyclase (ACA) | Null |
| rnpA | 82D, RNP | putative RNA binding protein RNP | DDB0214833 | increased post-aggregative gene expression | Null |
| rtoA | RatioA | unknown | DDB0185120 | delayed culmination, delayed development, endocytosis defect, increased number of prestalk cells, increased resistance to infection by Legionella pneumophila | Null |
| rzpA | rZIP | RING/leucine zipper protein | DDB0191162 | delayed development, increased aggregate size, increased expression of prespore cell markers, increased expression of prestalk cell markers, reduced slug migration | Null |
| rzpA | rZIP | RING/leucine zipper protein | DDB0191162 | increased expression of prestalk cell markers, reduced expression of prespore cell markers | OE |
|
scrA | SCAR | SCAR1 | DDB0191148 | multiple tips, precocious development, small fruiting bodies | Null |
| sfbA | DG1008, ORF1008 | unknown | DDB0185229 | small fruiting bodies | Null |
| sglA | | S1P lyase, sphingosine-1-phosphate lyase | DDB0214888 | aberrant fruiting bodies, increased resistance to cisplatin, reduced chemotaxis rate, reduced expression of prespore cell markers, reduced number of spores | Null |
| shkA | SHK1 | SH2 domain-containing protein, dual-specificity protein kinase, tyrosine kinase-like (TKL) protein | DDB0191149 | aggregation defective, reduced cell polarity, reduced chemotaxis rate, small fruiting bodies | Null |
| smlA | | unknown | DDB0191525 | increased basal level of F-actin, increased cAMP-induced cAMP pulse, increased level of ABP120 protein, increased level of extracellular counting factor component(s), increased myosin II assembly, reduced GTP-gamma-S-stimulated guanylyl cyclase (GC) activity, reduced cAMP-induced cGMP pulse, reduced secretion of lyzosomal enzymes, small fruiting bodies | Null |
| spiA | Dd31 | spore coat protein | DDB0191438 | reduced spore viability | Null |
| spkA | SAPKalpha | SAM domain-containing protein, ankyrin repeat-containing protein, stress-activated MEK-like kinase, tyrosine kinase-like (TKL) protein | DDB0185206 | reduced aggregate size, reduced cell polarity, reduced chemotaxis rate, reduced substrate adhesion, small fruiting bodies | Null |
| splA | DPYK1, KYK1 | dual-specificity protein kinase, non-receptor tyrosine kinase, tyrosine kinase-like (TKL) protein | DDB0215670 | aberrant spore morphology, defective spore differentiation, large sori, reduced spore viability, short stalks, translucent sori | Null |
| spnA | Spalten, Spn | protein serine/threonine phosphatase | DDB0185064 | aberrant development, defective spore differentiation, defective stalk cell differentiation, development arrests at mound stage | Null |
| srfA | DdSRF, SRF | MADS-box transcription factor, SRF-related protein | DDB0214892 | aberrant fruiting bodies, aberrant spore coat morphology, aberrant spore morphology, delayed culmination, reduced expression of spore genes, reduced slug migration, reduced spore viability | Null |
| stkA | | putative GATA-binding transcription factor | DDB0185187 | aberrant fruiting bodies, delayed expression of prespore genes, increased expression of prestalk cell markers, increased number of prestalk cells, reduced expression of spore genes | Null |
| tafA | | TBP-associated factor A | DDB0214904 | aberrant development | Null |
| tagA | | ABC transporter B family protein, serine protease | DDB0229852 | multiple tips, reduced spore viability | Null |
| tagB | | ABC transporter B family protein, serine protease | DDB0191217 | aberrant prestalk A cell differentiation, abolished DIF-1 production, development arrests at mound stage | Null |
| tagC | | ABC transporter B family protein, serine protease | DDB0191192 | spores inviable | Null |
| tagC | | ABC transporter B family protein, serine protease | DDB0191192 | development arrests at mound stage | Multiple |
| talB | | talin homologue | DDB0191526 | development arrests at mound stage | Null |
| tipA | | protein phosphatase 2C-like domain-containing protein | DDB0214906 | defective spore differentiation, defective stalk cell differentiation, development arrests at mound stage, increased aggregate size, multiple tips | Null |
| tipB | | unknown | DDB0191288 | development arrests at mound stage, increased aggregate size, multiple tips | Null |
| tipC | | unknown | DDB0191112 | development arrests at mound stage, increased aggregate size, multiple tips | Null |
| tipD | | homolog of mouse apg16L | DDB0215341 | development arrests at mound stage, increased aggregate size, multiple tips | Null |
| trap1 | Dd-trap1 | TNF receptor-associated protein | DDB0185036 | aberrant spore morphology, delayed development, reduced resistance to heat shock | Other |
| trap1 | Dd-trap1 | TNF receptor-associated protein | DDB0185036 | development arrests at loose aggregate stage, precocious aggregation | OE |
| trap1 | Dd-trap1 | TNF receptor-associated protein | DDB0185036 | delayed aggregation, small fruiting bodies | Multiple |
| ubcB | | ubiquitin conjugating enzyme | DDB0201564 | development arrests at mound stage, multiple tips | Null |
| ubpA | | deubiquitinating enzyme | DDB0231492 | aggregation defective, reduced cAMP-induced cAMP pulse, reduced chemotaxis rate, reduced expression of aggregation genes | Null |
| ubpB | | deubiquinating enzyme, ubiquitin hydrolase B | DDB0191402 | increased expression of prestalk cell markers, precocious development, reduced expression of prespore cell markers | Null |
| vwkA | | VWFA domain-containing protein, alpha kinase, protein serine/threonine kinase | DDB0216405 | aberrant fruiting bodies, delayed development, increased level of myosin protein, increased myosin II assembly | Null |
| vwkA | | VWFA domain-containing protein, alpha kinase, protein serine/threonine kinase | DDB0216405 | development arrests at mound stage, increased level of myosin protein, increased myosin II assembly, reduced sorting to prestalk region | OE |
| warA | hbx1, wariai, wri | homeodomain (HOX) containing protein, putative homeobox transcription factor | DDB0191441 | development arrests at slug stage, increased number of pstO cells, reduced number of prespore cells | Null |
| warA | hbx1, wariai, wri | homeodomain (HOX) containing protein, putative homeobox transcription factor | DDB0191441 | development arrests at mound stage, increased basal disc size, increased number of pstO cells | Multiple |
| wimA | DG1053, DG1064 | RmlC-like cupin family protein | DDB0191321 | aberrant fruiting bodies | Null |
| yakA | dagB | CMGC family protein kinase, DYRK family protein kinase, protein serine/threonine kinase | DDB0191191 | aggregation defective | Null |
| yelA | DG1014 | initiation factor eIF-4 gamma middle domain-containing protein | DDB0214918 | aberrant mound color, development arrests at mound stage, precocious spore differentiation, reduced spore viability | Null |
| zakA | ZAK1 | protein tyrosine kinase, tyrosine kinase-like (TKL) protein | DDB0185184 | aberrant fruiting bodies, defective spore differentiation, delayed culmination, reduced GSK3 (gen synthase kinase 3) activity | Null |
| zipA | DG1050 | zipper-like domain-containing protein | DDB0191488 | aberrant fruiting bodies | Null |
