Dictyostelium Phenotype Ontology format-version: 1.2
date: 31:08:2021 17:45
saved-by: pfey
auto-generated-by: OBO-Edit 2.2
default-namespace: Dicty Phenotypes
cAMP oscillatory signalingformat-version: 1.2
multiple tipsformat-version: 1.2
property_value: http://purl.org/dc/elements/1.1/description "A structured controlled vocabulary of phenotypes of the slime-mould Dictyostelium discoideum." xsd:string
property_value: http://purl.org/dc/elements/1.1/title "Dicty Phenotype Ontology (DDPHENO)" xsd:string
property_value: http://purl.org/dc/terms/license http://creativecommons.org/publicdomain/zero/1.0/
ontology: ddpheno

[Term]
id: DDPHENO:0000001
name: aberrant spore color
def: "Deviation from the normal, usual, or expected spore color." [DDB:pf]
synonym: "aberrant spore pigmentation" EXACT []
is_a: DDPHENO:0000513 ! aberrant sporulation
created_by: pfey
creation_date: 2013-08-14T16:28:20Z

[Term]
id: DDPHENO:0000002
name: aberrant standing slug morphology
def: "Deviation from the normal, usual, or expected morphology of the standing slug (finger)." [DDB:pf]
synonym: "aberrant finger morphology" EXACT []
synonym: "curly fingers" BROAD []
is_a: DDPHENO:0001014 ! aberrant slug development
created_by: pfey
creation_date: 2013-08-15T16:54:08Z

[Term]
id: DDPHENO:0000003
name: increased migratory slug length
def: "Increase in relative or proportionate length of the slug." [DDB:pf]
synonym: "increased slug length" EXACT []
synonym: "long slug" EXACT []
xref: PMID:18366659 "DDANAT:0000008"
is_a: DDPHENO:0000160 ! increased migratory slug size
created_by: pfey
creation_date: 2013-08-16T15:21:25Z

[Term]
id: DDPHENO:0000004
name: decreased migratory slug size
def: "Decrease in relative or proportionate dimensions of the slug." [DDB:pf]
synonym: "decreased slug size" BROAD []
xref: PMID:18366659 "DDANAT:0000008"
is_a: DDPHENO:0001014 ! aberrant slug development
created_by: pfey
creation_date: 2013-08-27T16:36:33Z

[Term]
id: DDPHENO:0000005
name: aberrant autophagy
def: "Deviation from the normal, usual, or expected events during autophagy." [DDB:pf]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2013-09-23T14:27:57Z

[Term]
id: DDPHENO:0000006
name: increased autophagy
def: "Increase in extent, amount, or degree of autophagy." [DDB:pf]
is_a: DDPHENO:0000005 ! aberrant autophagy
created_by: pfey
creation_date: 2013-09-23T14:29:45Z

[Term]
id: DDPHENO:0000007
name: decreased autophagy
def: "Reduction in extent, amount, or degree of autophagy." [DDB:pf]
is_a: DDPHENO:0000005 ! aberrant autophagy
created_by: pfey
creation_date: 2013-09-23T14:30:03Z

[Term]
id: DDPHENO:0000008
name: aberrant post-transciptional gene silencing by RNA
def: "Deviation from the normal, usual, or expected events during post-transciptional gene silencing by RNA." [DDB:pf]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2013-10-28T15:52:58Z

[Term]
id: DDPHENO:0000009
name: aberrant fruiting body morphology
def: "Deviation from the normal, usual, or expected morphology of the fruiting body." [DDB:pg]
synonym: "aberrant sorocarp morphology" EXACT []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0000010
name: abolished post-transciptional gene silencing by RNA
def: "Complete inability for post-transciptional gene silencing by RNA." [DDB:pf]
is_a: DDPHENO:0000008 ! aberrant post-transciptional gene silencing by RNA
created_by: pfey
creation_date: 2013-10-28T15:57:20Z

[Term]
id: DDPHENO:0000011
name: decreased post-transciptional gene silencing by RNA
def: "Reduction in level of modification of post-transciptional gene silencing by RNA." [DDB:pf]
is_a: DDPHENO:0000008 ! aberrant post-transciptional gene silencing by RNA
created_by: pfey
creation_date: 2013-10-28T15:59:10Z

[Term]
id: DDPHENO:0000012
name: aberrant pre-miRNA processing
def: "Deviation from the normal, usual, or expected events during pre-miRNA processing." [DDB:pf]
synonym: "aberrant miRNA processing" BROAD []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2013-10-28T18:00:23Z

[Term]
id: DDPHENO:0000014
name: abolished pre-miRNA processing
def: "Complete inability for pre-miRNA processing." [DDB:pf]
synonym: "abolished miRNA processing" BROAD []
is_a: DDPHENO:0000012 ! aberrant pre-miRNA processing
created_by: pfey
creation_date: 2013-10-28T18:01:47Z

[Term]
id: DDPHENO:0000015
name: increased pre-miRNA processing
def: "Increase in level of pre-miRNA processing." [DDB:pf]
synonym: "increased miRNA processing" BROAD []
is_a: DDPHENO:0000012 ! aberrant pre-miRNA processing
created_by: pfey
creation_date: 2013-10-28T18:03:08Z

[Term]
id: DDPHENO:0000016
name: decreased pre-miRNA processing
def: "Reduction in level of pre-miRNA processing." [DDB:pf]
synonym: "decreased miRNA processing" BROAD []
is_a: DDPHENO:0000012 ! aberrant pre-miRNA processing
created_by: pfey
creation_date: 2013-10-28T18:03:53Z

[Term]
id: DDPHENO:0000017
name: aberrant transitive RNA interference
def: "Deviation from the normal, usual, or expected events during transitive RNA interference." [DDB:pf]
synonym: "aberrant transitive RNAi" EXACT []
is_a: DDPHENO:0000020 ! aberrant RNA interference
created_by: pfey
creation_date: 2013-11-06T10:25:06Z

[Term]
id: DDPHENO:0000018
name: abolished transitive RNA interference
def: "Complete inability for transitive RNA interference." [DDB:pf]
synonym: "abolished transitive RNAi" EXACT []
is_a: DDPHENO:0000017 ! aberrant transitive RNA interference
created_by: pfey
creation_date: 2013-11-06T10:26:55Z

[Term]
id: DDPHENO:0000019
name: abolished culmination
def: "Complete inability for culmination." [DDB:pg]
synonym: "abolished culmination involved in sorocarp development" EXACT []
synonym: "culmination defective" RELATED []
is_a: DDPHENO:0001015 ! aberrant culmination

[Term]
id: DDPHENO:0000020
name: aberrant RNA interference
def: "Deviation from the normal, usual, or expected events during RNA interference." [DDB:pf]
synonym: "aberrant RNAi" RELATED []
is_a: DDPHENO:0000008 ! aberrant post-transciptional gene silencing by RNA
created_by: pfey
creation_date: 2013-11-06T10:35:04Z

[Term]
id: DDPHENO:0000021
name: abolished RNA interference
def: "Complete inability for RNA interference." [DDB:pf]
synonym: "abolished RNAi" RELATED []
is_a: DDPHENO:0000020 ! aberrant RNA interference
created_by: pfey
creation_date: 2013-11-06T10:38:10Z

[Term]
id: DDPHENO:0000022
name: aberrant production of siRNA involved in RNA interference
def: "Deviation from the normal, usual, or expected events during production of siRNA involved in RNA interference." [DDB:pf]
synonym: "aberrant production of siRNA involved in RNAi" EXACT []
is_a: DDPHENO:0000020 ! aberrant RNA interference
created_by: pfey
creation_date: 2013-11-06T11:17:36Z

[Term]
id: DDPHENO:0000024
name: abolished production of siRNA involved in RNA interference
def: "Complete inability for production of siRNA involved in RNA interference." [DDB:pf]
synonym: "abolished production of siRNA involved in RNAi" EXACT []
is_a: DDPHENO:0000022 ! aberrant production of siRNA involved in RNA interference
created_by: pfey
creation_date: 2013-11-06T11:20:17Z

[Term]
id: DDPHENO:0000025
name: abolished exocytosis
def: "Complete inability for exocytosis." [DDB:pf]
is_a: DDPHENO:0001110 ! aberrant exocytosis
created_by: pfey
creation_date: 2013-12-02T17:36:22Z

[Term]
id: DDPHENO:0000026
name: development arrests at mound stage
alt_id: DDPHENO:0000319
def: "Development cannot progress past the mound stage." [DDB:pf]
synonym: "development arrests at aggregate stage" EXACT []
synonym: "development arrests at tight aggregate stage" NARROW []
synonym: "development arrests at tight mound stage" NARROW []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0000027
name: abolished phagosome reneutralization
def: "Complete inability for phagosome reneutralization." [DDB:pf]
is_a: DDPHENO:0001488 ! aberrant phagosome maturation
created_by: pfey
creation_date: 2013-12-02T17:39:10Z

[Term]
id: DDPHENO:0000028
name: abolished stalk development
def: "Complete inability for stalk development." [DDB:pg]
synonym: "abolished stalk formation" RELATED []
is_a: DDPHENO:0001012 ! aberrant stalk development

[Term]
id: DDPHENO:0000029
name: increased resistance to N-Phenylthiourea
def: "Increase in extent, amount, or degree of resistance to N-Phenylthiourea." [DDB:pf]
is_a: DDPHENO:0000041 ! aberrant response to N-Phenylthiourea
created_by: pfey
creation_date: 2014-01-16T15:06:08Z

[Term]
id: DDPHENO:0000030
name: abolished slug development
def: "Complete inability to form slugs during development." [DDB:pf]
synonym: "abolished slug development involved in sorocarp development" EXACT []
synonym: "abolished slug formation" RELATED []
is_a: DDPHENO:0001014 ! aberrant slug development
created_by: pfey
creation_date: 2014-01-24T13:54:53Z

[Term]
id: DDPHENO:0000031
name: obsolete abolished rate of endocytosis
def: "OBSOLETE. Complete inability for rendocytosis." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2014-01-27T14:30:48Z

[Term]
id: DDPHENO:0000032
name: increased sporulation
def: "Increase in extent, amount, or degree of spore formation." [DDB:pf]
synonym: "increased number of spore cells" RELATED []
synonym: "increased number of spores" RELATED []
is_a: DDPHENO:0000513 ! aberrant sporulation

[Term]
id: DDPHENO:0000033
name: aberrant secretion
def: "Deviation from the normal, usual, or expected events during secretion of a substance." [DDB:pf]
is_a: DDPHENO:0001047 ! aberrant transport
created_by: pfey
creation_date: 2014-01-27T14:34:52Z

[Term]
id: DDPHENO:0000034
name: aberrant contractile vacuole discharge
def: "Deviation from the normal, usual, or expected events during contractile vacuole discharge." [DDB:pf]
is_a: DDPHENO:0000033 ! aberrant secretion
is_a: DDPHENO:0001110 ! aberrant exocytosis
created_by: pfey
creation_date: 2014-01-27T16:14:28Z

[Term]
id: DDPHENO:0000035
name: abolished contractile vacuole discharge
def: "Complete inability for contractile vacuole discharge." [DDB:pf]
is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge
created_by: pfey
creation_date: 2014-01-27T16:15:45Z

[Term]
id: DDPHENO:0000036
name: increased number of tip-organizers
def: "Increase in extend, amount, or degree of the number of tips." [DDB:pf]
synonym: "increased number of tips" EXACT []
synonym: "multiple tips" EXACT []
is_a: DDPHENO:0000009 ! aberrant fruiting body morphology
is_a: DDPHENO:0001431 ! aberrant development of tipped mound

[Term]
id: DDPHENO:0000037
name: decreased contractile vacuole discharge
def: "Reduction in extent, amount, or degree of contractile vacuole discharge." [DDB:pf]
is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge
created_by: pfey
creation_date: 2014-01-27T16:16:48Z

[Term]
id: DDPHENO:0000038
name: increased contractile vacuole discharge
def: "Increase in extent, amount, or degree of contractile vacuole discharge." [DDB:pf]
is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge
created_by: pfey
creation_date: 2014-01-27T16:17:55Z

[Term]
id: DDPHENO:0000039
name: aberrant plasma membrane organization
def: "Deviation from the normal, usual, or expected events during plasma membrane organization." [DDB:pf]
synonym: "aberrant plasma membrane circulation" RELATED []
synonym: "aberrant plasma membrane organization and biogenesis" EXACT []
is_a: DDPHENO:0001042 ! aberrant cellular component organization
created_by: pfey
creation_date: 2014-01-27T16:39:23Z

[Term]
id: DDPHENO:0000040
name: aberrant response to chemical
def: "Deviation from the normal, usual, or expected events during the response to a chemical." [DDB:pf]
synonym: "aberrant response to chemical stimulus" RELATED []
is_a: DDPHENO:0001003 ! aberrant response to stimulus
created_by: pfey
creation_date: 2014-03-20T12:02:35Z

[Term]
id: DDPHENO:0000041
name: aberrant response to N-Phenylthiourea
def: "Deviation from the normal, usual, or expected events during the response to N-Phenylthiourea." [DDB:pf]
is_a: DDPHENO:0000040 ! aberrant response to chemical
created_by: pfey
creation_date: 2014-03-20T12:09:31Z

[Term]
id: DDPHENO:0000042
name: aberrant membrane ruffling
def: "Deviation from the normal, usual, or expected events during membrane ruffling." [DDB:pf]
synonym: "aberrant ruffle assembly" EXACT []
is_a: DDPHENO:0001042 ! aberrant cellular component organization
created_by: pfey
creation_date: 2014-03-20T13:02:03Z

[Term]
id: DDPHENO:0000043
name: decreased membrane ruffling
def: "Reduction in extent, amount, or degree of membrane ruffling." [DDB:pf]
synonym: "decreased ruffle assembly" EXACT []
is_a: DDPHENO:0000042 ! aberrant membrane ruffling
created_by: pfey
creation_date: 2014-03-20T13:04:44Z

[Term]
id: DDPHENO:0000044
name: obsolete aberrant SDF production
def: "OBSLOTETE. Deviation from the normal, usual, or expected events during SDF production." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2014-03-20T13:59:32Z

[Term]
id: DDPHENO:0000045
name: aberrant phosphatidylinositol metabolism
def: "Deviation from the normal, usual, or expected events during phosphatidylinositol metabolism." [DDB:pf]
synonym: "aberrant phosphatidylinositol metabolic process" EXACT []
synonym: "aberrant phosphoinositide metabolism" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2014-03-20T14:03:28Z

[Term]
id: DDPHENO:0000046
name: aberrant phosphatidylinositol biosynthesis
def: "Deviation from the normal, usual, or expected events during phosphatidylinositol biosynthesis." [DDB:pf]
synonym: "aberrant phosphatidylinositol biosynthetic process" EXACT []
is_a: DDPHENO:0000045 ! aberrant phosphatidylinositol metabolism
created_by: pfey
creation_date: 2014-03-20T14:07:21Z

[Term]
id: DDPHENO:0000047
name: decreased phosphatidylinositol biosynthesis
def: "Reduction in extent, amount, or degree of phosphatidylinositol biosynthesis." [DDB:pf]
synonym: "decreased phosphatidylinositol biosynthetic process" EXACT []
is_a: DDPHENO:0000046 ! aberrant phosphatidylinositol biosynthesis
created_by: pfey
creation_date: 2014-03-20T14:09:34Z

[Term]
id: DDPHENO:0000048
name: increased phosphatidylinositol biosynthesis
def: "Increase in amount or accumulation of phosphatidylinositol biosynthesis." [DDB:pf]
synonym: "increased phosphatidylinositol biosynthetic process" EXACT []
is_a: DDPHENO:0000046 ! aberrant phosphatidylinositol biosynthesis
created_by: pfey
creation_date: 2014-03-20T14:10:51Z

[Term]
id: DDPHENO:0000049
name: abolished phosphatidylinositol biosynthesis
def: "Complete inability for the production of phosphatidylinositol." [DDB:pf]
synonym: "abolished phosphatidylinositol biosynthetic process" EXACT []
is_a: DDPHENO:0000046 ! aberrant phosphatidylinositol biosynthesis
created_by: pfey
creation_date: 2014-03-20T14:12:10Z

[Term]
id: DDPHENO:0000050
name: abolished hypotonic response
def: "Complete inability to respond to hypo-osmotic stress." [DDB:pf]
synonym: "abolished response to hypo-osmotic stress" EXACT []
synonym: "abolished response to hypotonic stress" EXACT []
is_a: DDPHENO:0001068 ! aberrant hypotonic response
created_by: pfey
creation_date: 2014-03-26T09:43:34Z

[Term]
id: DDPHENO:0000051
name: decreased hypotonic response
def: "Reduction in extent, amount, or degree of the response to hypo-osmotic stress." [DDB:pf]
synonym: "decreased response to hypo-osmotic stress" EXACT []
synonym: "decreased response to hypotonic stress" EXACT []
is_a: DDPHENO:0001068 ! aberrant hypotonic response
created_by: pfey
creation_date: 2014-03-26T09:45:52Z

[Term]
id: DDPHENO:0000052
name: increased hypotonic response
def: "Increase in extent, amount, or degree of the response to hypo-osmotic stress." [DDB:pf]
synonym: "increased response to hypo-osmotic stress" EXACT []
synonym: "increased response to hypotonic stress" EXACT []
is_a: DDPHENO:0001068 ! aberrant hypotonic response
created_by: pfey
creation_date: 2014-03-26T09:49:08Z

[Term]
id: DDPHENO:0000053
name: decreased contractile vacuole size
def: "Decrease in relative or proportionate dimensions of the contractile vacuole." [DDB:pf]
is_a: DDPHENO:0001066 ! aberrant contractile vacuole morphology
created_by: pfey
creation_date: 2014-03-26T09:52:55Z

[Term]
id: DDPHENO:0000077
name: decreased fruiting body size
def: "Reduction in relative or proportionate dimensions of the fruiting body." [DDB:pf]
synonym: "decreased sorocarp size" EXACT []
synonym: "small fruiting body" EXACT []
is_a: DDPHENO:0000009 ! aberrant fruiting body morphology

[Term]
id: DDPHENO:0000090
name: aberrant endocytosis
def: "Deviation from the normal, usual, or expected events during endocytosis." [DDB:pg]
synonym: "endocytosis defect" RELATED []
is_a: DDPHENO:0001047 ! aberrant transport

[Term]
id: DDPHENO:0000094
name: obsolete spores inviable
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0000098
name: aberrant prestalk A cell differentiation
def: "Deviation from the normal, usual, or expected events during differentiation of prestalk A cells." [DDB:pg]
synonym: "aberrant pstA cell differentiation" EXACT []
is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation

[Term]
id: DDPHENO:0000099
name: decreased chemotaxis rate
def: "Reduction in extent, amount, or degree of chemotaxis rate during the locomotory response to a chemical concentration gradient." [DDB:kp]
is_a: DDPHENO:0000148 ! decreased cell motility
is_a: DDPHENO:0001122 ! aberrant chemotaxis
is_a: DDPHENO:0001130 ! decreased taxis

[Term]
id: DDPHENO:0000102
name: increased number of mounds
def: "Quantitative increase in mounds." [DDB:pg]
synonym: "increased number of aggregates" EXACT []
is_a: DDPHENO:0000483 ! aberrant aggregation

[Term]
id: DDPHENO:0000104
name: aberrant protein localization to nucleolus
alt_id: DDPHENO:0000097
def: "Deviation from the normal, usual, or expected events during localization of a protein to the nucleolus." [DDB:pf]
synonym: "aberrant localization to nucleolus" BROAD []
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2014-05-21T10:46:32Z

[Term]
id: DDPHENO:0000105
name: abolished protein localization to nucleolus
alt_id: DDPHENO:0000100
def: "Complete inability to localize a protein to the nucleolus." [DDB:pf]
synonym: "abolished localization to nucleolus" BROAD []
is_a: DDPHENO:0000104 ! aberrant protein localization to nucleolus
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2014-05-21T10:46:58Z

[Term]
id: DDPHENO:0000106
name: decreased protein localization to nucleolus
alt_id: DDPHENO:0000103
def: "Reduction in amount or accumulation of a protein to the nucleolus." [DDB:pf]
synonym: "decreased localization to nucleolus" BROAD []
is_a: DDPHENO:0000104 ! aberrant protein localization to nucleolus
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2014-05-21T10:47:16Z

[Term]
id: DDPHENO:0000107
name: increased protein localization to nucleolus
alt_id: DDPHENO:0000101
def: "Increase in amount or accumulation of a protein at the nucleolus." [DDB:pf]
synonym: "increased localization to nucleolus" BROAD []
is_a: DDPHENO:0000104 ! aberrant protein localization to nucleolus
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2014-05-21T10:47:28Z

[Term]
id: DDPHENO:0000108
name: increased glucose level
def: "Increase in amount or accumulation of cytosolic glucose." [DDB:pg]
synonym: "increased cytosolic glucose level" NARROW []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0000109
name: increased cell-cell adhesion
def: "Increase in extent, amount, or degree of cell-cell adhesion." [DDB:pg]
is_a: DDPHENO:0000412 ! aberrant cell-cell adhesion

[Term]
id: DDPHENO:0000110
name: abolished cellular localization
def: "Complete inability to localize to a cellular compartment or structure." [DDB:pf]
comment: Use for mutated gene products that do not localize to their typical cellular compartment compared to the wild type gene product.
is_a: DDPHENO:0001217 ! aberrant cellular localization
created_by: pfey
creation_date: 2014-06-02T11:45:51Z

[Term]
id: DDPHENO:0000111
name: increased mound size
alt_id: DDPHENO:0001018
def: "Increase in relative or proportionate dimensions of the mound." [DDB:pf]
synonym: "aberrant negative regulation of aggregate size" RELATED []
synonym: "increased aggregate size" EXACT []
is_a: DDPHENO:0001017 ! aberrant mound size

[Term]
id: DDPHENO:0000112
name: decreased cellular localization
def: "Reduction in amount or accumulation at a certain cellular location." [DDB:pf]
comment: Use for mutated gene products that do not localize to their typical cellular compartment compared to the wild type gene product.
is_a: DDPHENO:0001217 ! aberrant cellular localization
created_by: pfey
creation_date: 2014-06-02T11:49:54Z

[Term]
id: DDPHENO:0000113
name: increased cellular localization
def: "Increase in amount or accumulation at a certain cellular location." [DDB:pf]
comment: Use for mutated gene products that do not localize to their typical cellular compartment compared to the wild type gene product.
is_a: DDPHENO:0001217 ! aberrant cellular localization
created_by: pfey
creation_date: 2014-06-02T11:50:23Z

[Term]
id: DDPHENO:0000115
name: aberrant substrate adhesion-dependent cell spreading
def: "Deviation from the normal, usual, or expected events during substrate adhesion-dependent cell spreading." [DDB:pf]
synonym: "aberrant cell spreading during cell substrate adhesion" EXACT []
synonym: "aberrant substrate adhesion dependent cell spreading" EXACT []
is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion
created_by: pfey
creation_date: 2014-08-27T11:05:50Z

[Term]
id: DDPHENO:0000116
name: increased cell motility
def: "Increase in extent, amount, or degree of cell motility." [DD:pg]
is_a: DDPHENO:0000264 ! aberrant cell motility

[Term]
id: DDPHENO:0000117
name: abolished substrate adhesion-dependent cell spreading
def: "Complete inability for substrate adhesion-dependent cell spreading." [DDB:pf]
synonym: "abolished cell spreading during cell substrate adhesion" EXACT []
synonym: "abolished substrate adhesion dependent cell spreading" EXACT []
is_a: DDPHENO:0000115 ! aberrant substrate adhesion-dependent cell spreading
created_by: pfey
creation_date: 2014-08-27T11:08:28Z

[Term]
id: DDPHENO:0000118
name: decreased substrate adhesion-dependent cell spreading
def: "Reduction in extent, amount, or degree of substrate adhesion-dependent cell spreading." [DDB:pf]
synonym: "decreased cell spreading during cell substrate adhesion" EXACT []
synonym: "decreased substrate adhesion dependent cell spreading" EXACT []
synonym: "reduced cell spreading during cell substrate adhesion" EXACT []
synonym: "reduced substrate adhesion dependent cell spreading" EXACT []
synonym: "reduced substrate adhesion-dependent cell spreading" EXACT []
is_a: DDPHENO:0000115 ! aberrant substrate adhesion-dependent cell spreading
created_by: pfey
creation_date: 2014-08-27T11:10:54Z

[Term]
id: DDPHENO:0000119
name: increased substrate adhesion-dependent cell spreading
def: "Increase in extent, amount, or degree of substrate adhesion-dependent cell spreading." [DDB:pf]
synonym: "increased cell spreading during cell substrate adhesion" EXACT []
synonym: "increased substrate adhesion dependent cell spreading" EXACT []
is_a: DDPHENO:0000115 ! aberrant substrate adhesion-dependent cell spreading
created_by: pfey
creation_date: 2014-08-27T11:11:10Z

[Term]
id: DDPHENO:0000120
name: aberrant cell-cell recognition
def: "Deviation from the normal, usual, or expected events during cell-cell recognition." [DDB:pf]
is_a: DDPHENO:0001008 ! aberrant cellular process
created_by: pfey
creation_date: 2014-10-02T14:41:25Z

[Term]
id: DDPHENO:0000121
name: decreased glucose level
def: "Reduction in extent, amount or accumulation of cytosolic glucose." [DDB:pg]
synonym: "decreased cytosolic glucose level" NARROW []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0000122
name: aberrant cell-cell self recognition
def: "Deviation from the normal, usual, or expected events during cell-cell self recognition." [DDB:pf]
synonym: "aberrant kin discrimination" RELATED []
synonym: "aberrant kin recognition" BROAD []
synonym: "aberrant self recognition" BROAD []
is_a: DDPHENO:0000120 ! aberrant cell-cell recognition
created_by: pfey
creation_date: 2014-10-02T14:42:58Z

[Term]
id: DDPHENO:0000123
name: decreased cGMP-mediated signaling
alt_id: DDPHENO:0000199
def: "Reduction in extent, amount, or degree of cGMP-mediated signaling." [DDB:pf]
synonym: "decreased cAMP-induced cGMP pulse" RELATED []
synonym: "decreased cyclic GMP-mediated signaling" EXACT []
is_a: DDPHENO:0000694 ! aberrant cGMP-mediated signaling

[Term]
id: DDPHENO:0000124
name: obsolete increased cAMP-induced cAMP pulse
def: "OBSOLETE. Increase in extent, amount, or degree of cAMP pulse in response to cAMP." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000125
name: abolished cell-cell self recognition
def: "Complete inability to perform cell-cell self recognition." [DDB:pf]
synonym: "abolished kin discrimination" RELATED []
synonym: "abolished kin recognition" BROAD []
synonym: "abolished self recognition" BROAD []
is_a: DDPHENO:0000122 ! aberrant cell-cell self recognition
created_by: pfey
creation_date: 2014-10-02T14:52:26Z

[Term]
id: DDPHENO:0000126
name: increased cGMP-mediated signaling
def: "Increase in extent, amount, or degree of cGMP-mediated signaling." [DDB:pf]
synonym: "increased cAMP-induced cGMP pulse" RELATED []
synonym: "increased cyclic GMP-mediated signaling" EXACT []
is_a: DDPHENO:0000694 ! aberrant cGMP-mediated signaling

[Term]
id: DDPHENO:0000127
name: aberrant socially cooperative development
def: "Deviation from the normal, usual, or expected social cooperation during aggregation." [DDB:pf]
synonym: "" RELATED []
synonym: "aberrant social cooperation" BROAD []
synonym: "aberrant socially cooperative aggregation" NARROW []
is_a: DDPHENO:0000483 ! aberrant aggregation
created_by: pfey
creation_date: 2014-10-02T16:36:10Z

[Term]
id: DDPHENO:0000128
name: decreased socially cooperative development
def: "Reduction in social cooperation during development." [DDB:pf]
comment: Involves cheating during development; cheaters make more spores than their normal share in chimeras.
synonym: "cheating during development" NARROW []
synonym: "decreased social cooperation" BROAD []
is_a: DDPHENO:0000127 ! aberrant socially cooperative development
created_by: pfey
creation_date: 2014-10-02T16:37:23Z

[Term]
id: DDPHENO:0000129
name: increased resistance to naringenin
def: "Increase in extent, amount, or degree of resistance to the flavonoid naringenin." [DDB:pf]
is_a: DDPHENO:0000040 ! aberrant response to chemical
created_by: pfey
creation_date: 2014-11-06T12:16:28Z

[Term]
id: DDPHENO:0000130
name: obsolete decreased cAMP-induced cAMP pulse
def: "OBSOLETE. Reduction in extent, amount, or degree of cAMP pulse in response to cAMP." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000131
name: obsolete increased secretion of counting factor (CF)
def: "OBSOLETE. Increase in extent, amount, or degree of secretion of counting factor (CF)." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000132
name: increased actin filament bundle assembly
alt_id: DDPHENO:0000303
def: "Increase in amount or accumulation of actin filament bundle assembly." [DDB:pf]
synonym: "increased basal F-actin level" RELATED []
synonym: "increased basal filamentous actin level" RELATED []
is_a: DDPHENO:0000151 ! aberrant actin filament organization

[Term]
id: DDPHENO:0000133
name: obsolete increased ABP120 protein level
def: "OBSOLETE. Increase in extent, amount, or degree ABP120 protein level." [DDB:pg]
synonym: "increased level of ABP" EXACT []
is_obsolete: true

[Term]
id: DDPHENO:0000134
name: increased myosin II assembly
def: "Increase in extent, amount, or degree of assembly of myosin II." [DDB:pg]
is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization

[Term]
id: DDPHENO:0000135
name: obsolete decreased ABP120 protein level
def: "OBSOLETE. Reduction in extent, amount or accumulation of ABP120 level." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000136
name: decreased myosin II assembly
def: "Reduction in extent, amount, or degree of myosin II assembly." [DDB:pg]
is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization

[Term]
id: DDPHENO:0000137
name: decreased actin filament bundle assembly
def: "Reduction in amount or accumulation of actin filament bundle assembly." [DDB:pf]
synonym: "decreased basal F-actin level" RELATED []
synonym: "decreased basal filamentous actin level" RELATED []
is_a: DDPHENO:0000151 ! aberrant actin filament organization

[Term]
id: DDPHENO:0000138
name: decreased cell-cell adhesion
def: "Reduction in extent, amount, or degree of cell-cell adhesion." [DDB:pg]
is_a: DDPHENO:0000412 ! aberrant cell-cell adhesion

[Term]
id: DDPHENO:0000139
name: decreased sexual fusion
def: "Reduction in extent, amount, or degree of gamete fusion during macrocyst formation." [DDB:pf]
synonym: "decreased conjugation with cellular fusion" RELATED []
is_a: DDPHENO:0001010 ! aberrant macrocyst formation

[Term]
id: DDPHENO:0000140
name: decreased slime trail
def: "Reduction in amount or accumulation of the slime trail, acellular material from the surface sheath left behind the migratory slug." [DDB:pf]
synonym: "decreased slime trail accumulation" EXACT []
synonym: "weak slime trail" EXACT []
xref: PMID:4338436 "DDANAT:0000076"
is_a: DDPHENO:0001014 ! aberrant slug development

[Term]
id: DDPHENO:0000141
name: decreased negative chemotaxis
def: "Reduction in extent, amount, or degree of chemotaxis towards a decreasing chemical concentration." [DDB:pf]
is_a: DDPHENO:0001225 ! aberrant negative chemotaxis
created_by: pfey
creation_date: 2014-12-17T16:11:58Z

[Term]
id: DDPHENO:0000142
name: wild type
def: "No phenotypic difference has been reported compared to wild type." [DDB:pf]
synonym: "no known phenotype" RELATED []
is_a: DDPHENO:0010000 ! Dicty Phenotypes

[Term]
id: DDPHENO:0000144
name: increased negative chemotaxis
def: "Increase in extent, amount, or degree of chemotaxis towards a decreasing chemical concentration." [DDB:pf]
is_a: DDPHENO:0001225 ! aberrant negative chemotaxis
created_by: pfey
creation_date: 2014-12-17T16:14:48Z

[Term]
id: DDPHENO:0000145
name: obsolete decreased spore viability
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0000146
name: abolished negative chemotaxis
def: "Complete inability for negative chemotaxis." [DDB:pf]
is_a: DDPHENO:0001225 ! aberrant negative chemotaxis
created_by: pfey
creation_date: 2014-12-17T16:15:30Z

[Term]
id: DDPHENO:0000147
name: aberrant chemorepellant activity
def: "Deviation from the normal, usual, or expected activity in the directed movement of a motile cell towards a lower concentration of a signal." [DDB:pf]
comment: Chemorepellant activity is the counter part_of DDPHENO:0001225 negative chemotaxis.
synonym: "aberrant chemorepellent activity" EXACT []
is_a: DDPHENO:0001171 ! aberrant molecular function
created_by: pfey
creation_date: 2014-12-17T16:19:14Z

[Term]
id: DDPHENO:0000148
name: decreased cell motility
alt_id: DDPHENO:0000386
def: "Reduction in extent, amount, or degree of cell motility." [DDB:pg]
synonym: "decreased random cell locomotion" RELATED []
is_a: DDPHENO:0000264 ! aberrant cell motility

[Term]
id: DDPHENO:0000149
name: aberrant cytokinesis
def: "Deviation from the normal, usual, or expected events during cytokinesis." [DDB:pg]
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0000150
name: abolished chemorepellant activity
def: "Complete inability for chemorepellant activity." [DDB:pf]
synonym: "abolished chemorepellent activity" EXACT []
is_a: DDPHENO:0000147 ! aberrant chemorepellant activity
created_by: pfey
creation_date: 2014-12-17T16:25:50Z

[Term]
id: DDPHENO:0000151
name: aberrant actin filament organization
def: "Deviation from the normal, usual, or expected events during actin filament organization." [DDB:pg]
synonym: "aberrant F-actin organization" EXACT []
is_a: DDPHENO:0001481 ! aberrant actin cytoskeleton organization

[Term]
id: DDPHENO:0000152
name: increased chemorepellant activity
def: "Increase in extent, amount, or degree of chemorepellant activity." [DDB:pf]
synonym: "increased chemorepellent activity" EXACT []
is_a: DDPHENO:0000147 ! aberrant chemorepellant activity
created_by: pfey
creation_date: 2014-12-17T16:28:25Z

[Term]
id: DDPHENO:0000153
name: decreased chemorepellant activity
def: "Reduction in extent, amount, or degree of chemorepellant activity." [DDB:pf]
synonym: "decreased chemorepellent activity" EXACT []
is_a: DDPHENO:0000147 ! aberrant chemorepellant activity
created_by: pfey
creation_date: 2014-12-17T16:29:56Z

[Term]
id: DDPHENO:0000154
name: aberrant sorocarp development
alt_id: DDPHENO:0000143
alt_id: DDPHENO:0000374
alt_id: DDPHENO:0000380
def: "Deviation from the normal, usual, or expected events during sorocarp development." [DDB:pg]
synonym: "merged_development hypersensitive to ammonia" NARROW []
synonym: "merged_development is resistant to Li+" NARROW []
synonym: "merged_increased sensitivity to lithium" NARROW []
is_a: DDPHENO:0001003 ! aberrant response to stimulus

[Term]
id: DDPHENO:0000155
name: development arrests at tipped mound stage
def: "Development cannot progress past the tipped mound stage." [DDB:pf]
synonym: "development arrests at tipped aggregate stage" EXACT []
is_a: DDPHENO:0000026 ! development arrests at mound stage

[Term]
id: DDPHENO:0000156
name: delayed aggregation
alt_id: DDPHENO:0000502
alt_id: DDPHENO:0000548
def: "Late onset or slower progression through aggregation." [DDB:pg]
synonym: "delayed aggregation during fruiting body development" EXACT []
synonym: "delayed aggregation involved in sorocarp development" EXACT []
is_a: DDPHENO:0000483 ! aberrant aggregation

[Term]
id: DDPHENO:0000157
name: delayed development of tipped mound
def: "Late onset or slower progression through development of tipped mound." [DDB:pg]
synonym: "delayed sorocarp development of tipped mound" EXACT []
synonym: "delayed tip formation" RELATED []
is_a: DDPHENO:0000162 ! delayed development
is_a: DDPHENO:0001431 ! aberrant development of tipped mound

[Term]
id: DDPHENO:0000158
name: decreased mound size
alt_id: DDPHENO:0001019
def: "Reduction in relative or proportionate dimensions of the mound." [DDB:pf]
synonym: "decreased aggregate size" EXACT []
synonym: "decreased positive regulation of aggregate size" RELATED []
is_a: DDPHENO:0001017 ! aberrant mound size

[Term]
id: DDPHENO:0000159
name: development arrests at loose mound stage
alt_id: DDPHENO:0000505
alt_id: DDPHENO:0000506
alt_id: DDPHENO:0000507
def: "Development cannot progress past the loose mound stage." [DDB:pf]
synonym: "development arrests at loose aggregate stage" EXACT []
synonym: "development arrests at loose aggregate stage in the presence of EGTA" NARROW []
synonym: "development arrests at loose aggregate stage in the presence of TMB-8" NARROW []
synonym: "merged_development arrests at loose aggregate stage in the presence of lithium" NARROW []
is_a: DDPHENO:0000026 ! development arrests at mound stage

[Term]
id: DDPHENO:0000160
name: increased migratory slug size
def: "Increase in relative or proportionate dimensions of the slug." [DDB:pg]
synonym: "increased slug size" EXACT []
xref: PMID:18366659 "DDANAT:0000008"
is_a: DDPHENO:0001014 ! aberrant slug development

[Term]
id: DDPHENO:0000161
name: delayed culmination
def: "Late onset or slower progression through culmination." [DDBB:pg]
synonym: "delayed culmination involved in sorocarp development" EXACT []
is_a: DDPHENO:0001015 ! aberrant culmination

[Term]
id: DDPHENO:0000162
name: delayed development
alt_id: DDPHENO:0000418
alt_id: DDPHENO:0000508
def: "Late onset or slower progression through development." [DDB:pg]
synonym: "delayed sorocarp development" EXACT []
synonym: "merged_delayed development in the presence of gossypol" NARROW []
synonym: "merged_delayed development in the presence of lithium" NARROW []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0000163
name: aberrant spore morphology
def: "Deviation from the normal, usual, or expected morphology of the spore." [DDB:pg]
is_a: DDPHENO:0000236 ! aberrant cell morphology
is_a: DDPHENO:0000513 ! aberrant sporulation

[Term]
id: DDPHENO:0000164
name: aberrant regulation of chemorepellant activity
def: "Deviation from the normal, usual, or expected events during the regulation of chemorepellant activity." [DDB:pf]
synonym: "aberrant regulation of chemorepellent activity" EXACT []
is_a: DDPHENO:0000147 ! aberrant chemorepellant activity
created_by: pfey
creation_date: 2014-12-17T16:35:43Z

[Term]
id: DDPHENO:0000165
name: increased stalk length
def: "Having a relative long stalk." [DDB:pg]
synonym: "long stalk" EXACT []
synonym: "stalky" RELATED []
xref: PATO:0000573
is_a: DDPHENO:0000510 ! aberrant stalk morphogenesis

[Term]
id: DDPHENO:0000166
name: decreased sorus size
def: "Reduction in relative or proportionate dimensions of the sorus." [DDB:pg]
synonym: "small sori" RELATED []
is_a: DDPHENO:0000384 ! aberrant sorus morphology

[Term]
id: DDPHENO:0000167
name: precocious development
def: "Early onset or faster progression through development." [DDB:pg]
synonym: "precocious sorocarp development" EXACT []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0000168
name: development arrests at slug stage
def: "Development cannot progress past the migratory slug stage during development." [DDB:pf]
synonym: "development arrests at migratory slug stage" EXACT []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0000169
name: increased prestalk cell differentiation
def: "Increase in extent, amount, or degree of prestalk cell differentiation." [DDB:pg]
synonym: "increased number of prestalk cells" RELATED []
synonym: "increased number of pst cells" RELATED []
synonym: "increased pst cell differentiation" EXACT []
is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation
is_a: DDPHENO:0001174 ! increased cell differentiation

[Term]
id: DDPHENO:0000170
name: increased prespore cell differentiation
def: "Increase in extent, amount, or degree of differentiation into prespore cells." [DDB:pg]
synonym: "increased number of prespore cells" RELATED []
is_a: DDPHENO:0001025 ! aberrant prespore cell differentiation
is_a: DDPHENO:0001174 ! increased cell differentiation

[Term]
id: DDPHENO:0000171
name: increased growth rate
alt_id: DDPHENO:0000460
alt_id: DDPHENO:0000496
def: "Increase in extent, amount, or degree of cell proliferation." [DDB:pf]
synonym: "increased asexual reproduction" EXACT []
synonym: "increased growth rate in suspension" NARROW []
synonym: "increased growth rate on bacterial plates" NARROW []
is_a: DDPHENO:0001084 ! aberrant vegetative growth

[Term]
id: DDPHENO:0000172
name: obsolete insensitive to ammonia
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0000173
name: precocious spore germination
def: "Early onset or faster progression of release from spore dormancy." [DDB:pf]
is_a: DDPHENO:0001046 ! aberrant spore germination

[Term]
id: DDPHENO:0000175
name: decreased prespore cell differentiation
def: "Reduction in extent, amount, or degree of differentiation into prespore cells." [DDB:pg]
synonym: "decreased number of prespore cells" RELATED []
is_a: DDPHENO:0001025 ! aberrant prespore cell differentiation
is_a: DDPHENO:0001175 ! decreased cell differentiation

[Term]
id: DDPHENO:0000176
name: increased prestalk O cell differentiation
def: "Increase in extent, amount, or degree of differentiation into prestalk O cells." [DDB:pf]
synonym: "increased number of prestalk O cells" RELATED []
synonym: "increased number of pstO cells" RELATED []
synonym: "increased pstO cell differentiation" EXACT []
is_a: DDPHENO:0000169 ! increased prestalk cell differentiation
is_a: DDPHENO:0001024 ! aberrant prestalk O cell differentiation

[Term]
id: DDPHENO:0000177
name: aberrant positive regulation of chemorepellant activity
def: "Deviation from the normal, usual, or expected events during the positive regulation of chemorepellant activity." [DDB:pf]
synonym: "aberrant positive regulation of chemorepellent activity" EXACT []
is_a: DDPHENO:0000164 ! aberrant regulation of chemorepellant activity
created_by: pfey
creation_date: 2014-12-17T16:36:44Z

[Term]
id: DDPHENO:0000178
name: precocious development of tipped mound
def: "Early onset or faster progression through development of tipped mound." [DDB:pg]
synonym: "precocious sorocarp development of tipped mound" EXACT []
synonym: "precocious tip formation" RELATED []
is_a: DDPHENO:0000167 ! precocious development
is_a: DDPHENO:0001431 ! aberrant development of tipped mound

[Term]
id: DDPHENO:0000181
name: abolished slug migration
def: "Complete inability for slugs to migrate." [DDB:pg]
synonym: "abolished migratory slug locomotion" EXACT []
is_a: DDPHENO:0001077 ! aberrant slug migration

[Term]
id: DDPHENO:0000183
name: decreased number of astral microtubules
def: "Reduction in extent, amount, or degree of astral microtubules." [DDB:pf]
is_a: DDPHENO:0001002 ! aberrant organelle morphology

[Term]
id: DDPHENO:0000184
name: decreased size of astral microtubules
def: "Reduction in extent or length of astral microtubules." [DDB:pf]
is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization

[Term]
id: DDPHENO:0000185
name: decreased resistance to nocodazole
def: "Decreased tolerance of the normal, usual, or expected events towards nocodazole." [DDB:pf]
is_a: DDPHENO:0000362 ! aberrant response to nocodazole

[Term]
id: DDPHENO:0000187
name: aberrant cell-substrate adhesion
def: "Deviation from the normal, usual, or expected events during cell-substrate adhesion." [DDB:pg]
synonym: "aberrant substrate adhesion" RELATED []
synonym: "defective substrate adhesion" RELATED []
is_a: DDPHENO:0001044 ! aberrant cell adhesion

[Term]
id: DDPHENO:0000188
name: decreased phagocytosis
def: "Reduction in extent, amount, or degree of phagocytosis." [DDB:pg]
is_a: DDPHENO:0001006 ! aberrant phagocytosis

[Term]
id: DDPHENO:0000190
name: aberrant negative regulation of chemorepellant activity
def: "Deviation from the normal, usual, or expected events during the negative regulation of chemorepellant activity." [DDB:pf]
synonym: "aberrant negative regulation of chemorepellent activity" EXACT []
is_a: DDPHENO:0000164 ! aberrant regulation of chemorepellant activity
created_by: pfey
creation_date: 2014-12-17T16:38:07Z

[Term]
id: DDPHENO:0000191
name: decreased prestalk cell differentiation
def: "Reduction in extent, amount, or degree of differentiation into prestalk cells." [DDB:pg]
synonym: "decreased number of prestalk cells" RELATED []
synonym: "decreased number of pst cells" RELATED []
synonym: "decreased pst cell differentiation" EXACT []
is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation
is_a: DDPHENO:0001175 ! decreased cell differentiation

[Term]
id: DDPHENO:0000192
name: abolished prestalk O cell differentiation
def: "Complete inability for differentiation of prestalk O cells." [DDB:pf]
synonym: "abolished pstO differentiation" EXACT []
is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation
is_a: DDPHENO:0001024 ! aberrant prestalk O cell differentiation

[Term]
id: DDPHENO:0000193
name: abolished DIF-1 biosynthesis
def: "Complete inability for DIF biosynthesis." [DDB:pf]
synonym: "abolished DIF-1 biosynthetic process" EXACT []
synonym: "abolished DIF-1 production" RELATED []
synonym: "abolished differentiation inducing factor 1 biosynthesis" EXACT []
is_a: DDPHENO:0001095 ! aberrant DIF-1 biosynthesis

[Term]
id: DDPHENO:0000195
name: decreased stalk cell differentiation
def: "Reduction in extent, amount, or degree of differentiation into stalk cells." [DDB:pg]
synonym: "decreased number of stalk cells" RELATED []
is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation
is_a: DDPHENO:0001175 ! decreased cell differentiation

[Term]
id: DDPHENO:0000196
name: obsolete increased protein kinase A activity
def: "OBSOLETE. Increase in extent, amount, or degree of kinase a activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000197
name: obsolete increased GTP-gamma-S-stimulated guanylyl cyclase activity
def: "OBSOLETE. Increase in extent, amount, or degree of GTP-gamma-S-stimulated guanylyl cyclase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000198
name: aberrant activation of adenylate cyclase activity
def: "Deviation from the normal, usual, or expected events during the activation of adenylate cyclase." [DDB:pg]
comment: Replaced "defective in activation of adenylate cyclase (ACA)" with "aberrant activation of adenylate cyclase (ACA)"; annotations should be changed to "decreased" or "abolished" activation of adenylate cyclase. PG 10-11-2006.
synonym: "aberrant activation of ACA" EXACT []
synonym: "defective in activation of adenylate cyclase (ACA)" RELATED []
is_a: DDPHENO:0001118 ! aberrant signal transduction
is_a: DDPHENO:0001304 ! aberrant regulation of adenylate cyclase activity

[Term]
id: DDPHENO:0000200
name: obsolete decreased GTP-gamma-S-stimulated guanylyl cyclase activity
def: "OBSOLETE. Reduction in extent, amount, or degree of GTP-gamma-S-stimulated guanylyl cyclase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000201
name: obsolete decreased glycogen synthase kinase 3 activity
def: "OBSOLETE. Reduction in extent, amount, or degree of glycogen synthase kinase 3 activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000203
name: increased number of microtubule organizing center
def: "Quantitative increase in microtubule organizing centers." [DDB:pg]
is_a: DDPHENO:0000413 ! aberrant microtubule cytoskeleton organization

[Term]
id: DDPHENO:0000204
name: obsolete decreased extracellular counting factor component(s) level
def: "OBSOLETE. Reduction in extent, amount or accumulation of extracellular counting factor component level." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000205
name: obsolete decreased extracellular CF50 level
def: "OBSOLETE. Reduction in extent, amount or accumulation of extracellular CF50 level." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0000206
name: precocious aggregation
def: "Early onset or faster progression through aggregation." [DDB:pg]
synonym: "precocious aggregation during fruiting body development" EXACT []
synonym: "precocious aggregation involved in sorocarp development" EXACT []
is_a: DDPHENO:0000483 ! aberrant aggregation

[Term]
id: DDPHENO:0000207
name: increased standing slug length
def: "Increase in relative or proportionate length of the standing slug." [DDB:pf]
synonym: "long fingers" EXACT []
xref: PMID:18366659 "DDANAT:0000007 standing slug"
is_a: DDPHENO:0000002 ! aberrant standing slug morphology

[Term]
id: DDPHENO:0000208
name: decreased standing slug width
def: "Decrease in relative or proportionate width of the standing slug." [DDB:pf]
synonym: "thin fingers" EXACT []
synonym: "thin standing slug" EXACT []
xref: PMID:18366659 "DDANAT:0000007 standing slug"
is_a: DDPHENO:0000002 ! aberrant standing slug morphology

[Term]
id: DDPHENO:0000209
name: aberrant response to osmotic stress
def: "Deviation from the normal, usual, or expected events during the response to osmotic stress." [DDB:pg]
is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus
is_a: DDPHENO:0001034 ! aberrant cellular response to stress

[Term]
id: DDPHENO:0000210
name: delayed slug development
def: "Late onset or slower progression through slug development." [DDB:pg]
synonym: "delayed slug development involved in sorocarp development" EXACT []
synonym: "delayed slug formation" RELATED []
is_a: DDPHENO:0001014 ! aberrant slug development

[Term]
id: DDPHENO:0000211
name: aberrant cellular response to nitrogen starvation
def: "Deviation from the normal, usual, or expected events during the cellular response to nitrogen starvation." [DDB:pf]
is_a: DDPHENO:0001226 ! aberrant cellular response to extracellular stimulus

[Term]
id: DDPHENO:0000212
name: aberrant macroautophagy
def: "Deviation from the normal, usual, or expected events during macroautophagy." [DDB:pf]
is_a: DDPHENO:0001039 ! aberrant cellular response to starvation

[Term]
id: DDPHENO:0000213
name: increased cell-substrate adhesion
def: "Increase in extent, amount, or degree of cell-substrate adhesion." [DDB:pg]
synonym: "increased substrate adhesion" RELATED []
is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion

[Term]
id: DDPHENO:0000214
name: precocious sporulation
def: "Early onset or faster progression through spore formation." [DDB:pf]
synonym: "precocious spore differentiation" EXACT []
is_a: DDPHENO:0000513 ! aberrant sporulation

[Term]
id: DDPHENO:0000215
name: decreased spore resistance to hydrogen peroxide
def: "Decreased tolerance of the normal, usual, or expected events in spores towards hydrogen peroxide." [DDB:pf]
is_a: DDPHENO:0001046 ! aberrant spore germination

[Term]
id: DDPHENO:0000216
name: aberrant spore coat morphology
def: "Deviation from the normal, usual, or expected morphology of the spore coat." [DDB:pg]
synonym: "aberrant spore wall morphology" EXACT []
is_a: DDPHENO:0000163 ! aberrant spore morphology

[Term]
id: DDPHENO:0000222
name: aberrant phototaxis
def: "Deviation from the normal, usual, or expected events during the response to light." [DDB:pf]
is_a: DDPHENO:0001121 ! aberrant taxis

[Term]
id: DDPHENO:0000223
name: aberrant thermotaxis
def: "Deviation from the normal, usual, or expected events during the response to temperature changes." [DDB:pf]
is_a: DDPHENO:0001121 ! aberrant taxis

[Term]
id: DDPHENO:0000225
name: decreased slug migration
def: "Reduction in extent, amount, or degree of slug migration." [DDB:pg]
synonym: "decreased migratory slug locomotion" EXACT []
is_a: DDPHENO:0001077 ! aberrant slug migration

[Term]
id: DDPHENO:0000226
name: increased prestalk A cell differentiation
def: "Increase in extent, amount, or degree of differentiation into prestalk A cells." [DDB:pg]
synonym: "increased number of prestalk A cells" RELATED []
synonym: "increased number of pstA cells" RELATED []
synonym: "increased pstA cell differentiation" EXACT []
is_a: DDPHENO:0000098 ! aberrant prestalk A cell differentiation
is_a: DDPHENO:0000169 ! increased prestalk cell differentiation

[Term]
id: DDPHENO:0000227
name: abolished regulation of chemorepellant activity
def: "Complete inability of the regulation of chemorepellant activity." [DDB:pf]
synonym: "abolished regulation of chemorepellent activity" EXACT []
is_a: DDPHENO:0000147 ! aberrant chemorepellant activity
created_by: pfey
creation_date: 2014-12-17T16:39:18Z

[Term]
id: DDPHENO:0000228
name: abolished positive regulation of chemorepellant activity
def: "Complete inability of the positive regulation of chemorepellant activity." [DDB:pf]
synonym: "abolished positive regulation of chemorepellent activity" EXACT []
is_a: DDPHENO:0000227 ! abolished regulation of chemorepellant activity
created_by: pfey
creation_date: 2014-12-17T16:39:53Z

[Term]
id: DDPHENO:0000229
name: abolished negative regulation of chemorepellant activity
def: "Complete inability of the negative regulation of chemorepellant activity." [DDB:pf]
synonym: "abolished negative regulation of chemorepellent activity" EXACT []
is_a: DDPHENO:0000227 ! abolished regulation of chemorepellant activity
created_by: pfey
creation_date: 2014-12-17T16:40:31Z

[Term]
id: DDPHENO:0000230
name: aberrant endosome morphology
def: "Deviation from the normal, usual, or expected morphology of the endosome." [DDB:pg]
is_a: DDPHENO:0001002 ! aberrant organelle morphology

[Term]
id: DDPHENO:0000231
name: increased cell death
def: "Increase in extent, amount, or degree of cell death." [DDB:pf]
synonym: "decreased cell viability" RELATED []
is_a: DDPHENO:0001267 ! aberrant cell death
created_by: pfey
creation_date: 2014-12-19T15:32:33Z

[Term]
id: DDPHENO:0000232
name: decreased spore germination
def: "Reduction in extent, amount, or degree of release from spore dormancy." [DDB:pf]
synonym: "decreased spore viability" BROAD []
is_a: DDPHENO:0001046 ! aberrant spore germination

[Term]
id: DDPHENO:0000233
name: aberrant contractile vacuole organization
def: "Deviation from the normal, usual, or expected organization and biogenesis of the contractile vacuole." [DDB:pf]
is_a: DDPHENO:0001041 ! aberrant vacuole organization

[Term]
id: DDPHENO:0000234
name: aberrant mitosis
def: "Deviation from the normal, usual, or expected events during mitosis." [DDB:pg]
synonym: "mitotic nuclear division" EXACT []
is_a: DDPHENO:0001418 ! aberrant cell cycle

[Term]
id: DDPHENO:0000235
name: obsolete increased aneuploidy
def: "OBSOLETE. Increase in extent, amount, or degree of aneuploidy." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000236
name: aberrant cell morphology
def: "Deviation from the normal, usual, or expected morphology of a cell." [DDB:pg]
comment: Child of GO:0000902 : cellular morphogenesis.
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0000237
name: decreased cell death
def: "Reduction in extent, amount, or degree of cell death." [DDB:pf]
synonym: "increased cell viability" RELATED []
is_a: DDPHENO:0001267 ! aberrant cell death
created_by: pfey
creation_date: 2014-12-19T15:35:54Z

[Term]
id: DDPHENO:0000238
name: obsolete aberrant DNA mediated transformation
def: "OBSOLETE. Deviation from the normal, usual, or expected events during DNA-mediated transformation." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-01-27T11:45:54Z

[Term]
id: DDPHENO:0000239
name: obsolete decreased DNA mediated transformation
def: "OBSOLETE. Reduction in extent, amount or degree of DNA mediated transformation." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-01-27T11:48:35Z

[Term]
id: DDPHENO:0000240
name: obsolete increased DNA mediated transformation
def: "OBSOLETE. Increase in extent, amount, or degree of DNA mediated transformation." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-01-27T11:48:59Z

[Term]
id: DDPHENO:0000241
name: obsolete abolished DNA mediated transformation
def: "OBSOLETE. Complete inability for DNA-mediated transformation." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-01-29T14:57:44Z

[Term]
id: DDPHENO:0000242
name: aberrant DNA repair
def: "Deviation from the normal, usual, or expected events during DNA repair." [DDB:pf]
is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus
created_by: pfey
creation_date: 2015-02-12T14:58:49Z

[Term]
id: DDPHENO:0000243
name: aberrant single-strand break repair
def: "Deviation from the normal, usual, or expected events during single-strand break DNA repair." [DDB:pf]
is_a: DDPHENO:0000242 ! aberrant DNA repair
created_by: pfey
creation_date: 2015-02-12T14:59:35Z

[Term]
id: DDPHENO:0000244
name: aberrant double-strand break repair
def: "Deviation from the normal, usual, or expected events during double-strand break DNA repair." [DDB:pf]
synonym: "aberrant double strand break repair" EXACT []
synonym: "aberrant DSB repair" EXACT []
is_a: DDPHENO:0000242 ! aberrant DNA repair
created_by: pfey
creation_date: 2015-02-12T15:00:20Z

[Term]
id: DDPHENO:0000245
name: decreased double-strand break repair
def: "Reduction in extent, amount, or degree of double strand break DNA repair." [DDB:pf]
is_a: DDPHENO:0000244 ! aberrant double-strand break repair
created_by: pfey
creation_date: 2015-02-12T15:03:53Z

[Term]
id: DDPHENO:0000246
name: decreased single-strand break repair
def: "Reduction in extent, amount, or degree of single-strand break repair of DNA." [DDB:pf]
is_a: DDPHENO:0000243 ! aberrant single-strand break repair
created_by: pfey
creation_date: 2015-02-12T15:04:21Z

[Term]
id: DDPHENO:0000247
name: abolished double strand break repair
def: "Complete inability for double strand break DNA repair." [DDB:pf]
is_a: DDPHENO:0000244 ! aberrant double-strand break repair
created_by: pfey
creation_date: 2015-02-12T15:06:27Z

[Term]
id: DDPHENO:0000248
name: abolished single-strand break repair
def: "Complete inability for single-strand break repair of DNA." [DDB:pf]
is_a: DDPHENO:0000243 ! aberrant single-strand break repair
created_by: pfey
creation_date: 2015-02-12T15:06:50Z

[Term]
id: DDPHENO:0000249
name: increased double-strand break repair
def: "Increased tolerance of the normal, usual, or expected events in double-strand break repair." [DDB:pf]
is_a: DDPHENO:0000244 ! aberrant double-strand break repair
created_by: pfey
creation_date: 2015-02-12T16:01:50Z

[Term]
id: DDPHENO:0000250
name: increased single-strand break repair
def: "Increased tolerance of the normal, usual, or expected events in single-strand break repair of DNA." [DDB:pf]
is_a: DDPHENO:0000243 ! aberrant single-strand break repair
created_by: pfey
creation_date: 2015-02-12T16:02:13Z

[Term]
id: DDPHENO:0000251
name: aberrant regulation of mitochondrial membrane potential
def: "Deviation from the normal, usual, or expected events during regulation of the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [DDB:pf]
is_a: DDPHENO:0001008 ! aberrant cellular process
created_by: pfey
creation_date: 2015-03-04T16:27:33Z

[Term]
id: DDPHENO:0000252
name: aberrant positive regulation of mitochondrial membrane potential
def: "Deviation from the normal, usual, or expected events during positive regulation of the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [DDB:pf]
is_a: DDPHENO:0000251 ! aberrant regulation of mitochondrial membrane potential
created_by: pfey
creation_date: 2015-03-04T17:40:26Z

[Term]
id: DDPHENO:0000253
name: aberrant negative regulation of mitochondrial membrane potential
def: "Deviation from the normal, usual, or expected events during negative regulation of the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [DDB:pf]
is_a: DDPHENO:0000251 ! aberrant regulation of mitochondrial membrane potential
created_by: pfey
creation_date: 2015-03-04T17:41:03Z

[Term]
id: DDPHENO:0000254
name: aberrant cell motility in response to calcium ion
def: "Deviation from the normal, usual, or expected events during the locomotory response guided by increasing chemical concentration of calcium." [DDB:pf]
synonym: "aberrant chemotaxis to Ca2+" EXACT []
synonym: "aberrant chemotaxis to calcium" EXACT []
is_a: DDPHENO:0001224 ! aberrant positive chemotaxis
created_by: pfey
creation_date: 2015-04-13T16:41:24Z

[Term]
id: DDPHENO:0000255
name: obsolete aberrant potassium-dependent chemotaxis to cAMP
def: "OBSOLETE. Deviation from the normal, usual, or expected events during potassium-dependent chemotaxis to cAMP." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-04-13T16:57:18Z

[Term]
id: DDPHENO:0000256
name: obsolete abolished potassium-dependent chemotaxis to cAMP
def: "OBSOLETE. Complete inability for potassium-dependent chemotaxis to cAMP." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-04-13T17:39:42Z

[Term]
id: DDPHENO:0000257
name: abolished cell motility in response to calcium ion
def: "Complete inability for chemotaxis in response to calcium." [DDB:pf]
synonym: "abolished chemotaxis to Ca2+" EXACT []
synonym: "abolished chemotaxis to calcium" EXACT []
is_a: DDPHENO:0000254 ! aberrant cell motility in response to calcium ion
created_by: pfey
creation_date: 2015-04-13T17:42:45Z

[Term]
id: DDPHENO:0000258
name: aberrant defense response to bacterium
alt_id: DDPHENO:0000277
def: "Deviation from the normal, usual, or expected events during defense response to bacterium." [DDB:pf]
comment: Pathogenic bacteria are defined as being pathogens for humans, though in the any specific study a strain or species less virulent for humans may have been used.
synonym: "aberrant infection rate by pathogenic bacterium" NARROW []
is_a: DDPHENO:0001505 ! aberrant cellular defense response
created_by: pfey
creation_date: 2015-05-05T14:26:26Z

[Term]
id: DDPHENO:0000260
name: decreased cell migration to prestalk region
def: "Reduction in extent, amount, or degree of cell migration to prestalk region during the slug stage." [DDB:pg]
synonym: "decreased sorting to prestalk region" EXACT []
is_a: DDPHENO:0000306 ! aberrant cell migration to prestalk region

[Term]
id: DDPHENO:0000261
name: obsolete abolished prestalk cell differentiation in response to DIF-1
def: "OBSOLETE. Complete inability for prestalk cell differentiation in response to DIF-1." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000262
name: decreased prestalk O cell differentiation
def: "Reduction in extent, amount, or degree of differentiation into prestalk O cells." [DDB:pf]
synonym: "decreased number of prestalk O cells" RELATED []
synonym: "decreased number of pstO cells" RELATED []
synonym: "decreased pstO cell differentiation" EXACT []
is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation
is_a: DDPHENO:0001024 ! aberrant prestalk O cell differentiation

[Term]
id: DDPHENO:0000263
name: aberrant nucleus morphology
def: "Deviation from the normal, usual, or expected morphology of the nucleus." [DDB:pg]
synonym: "aberrant nuclear morphology" EXACT []
is_a: DDPHENO:0001002 ! aberrant organelle morphology
is_a: DDPHENO:0001536 ! aberrant nucleus organization

[Term]
id: DDPHENO:0000264
name: aberrant cell motility
def: "Deviation from the normal, usual, or expected events during cell motility." [DDB:pg]
comment: Child of GO:0006928 : cell motility.
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0000265
name: aberrant myosin II filament organization
def: "Deviation from the normal, usual, or expected events during myosin II organization." [DDB:pg]
synonym: "aberrant myosin II organization" EXACT []
is_a: DDPHENO:0000236 ! aberrant cell morphology

[Term]
id: DDPHENO:0000269
name: increased basal disc size
def: "Increase in relative or proportionate dimensions of the basal disc." [DDB:pg]
is_a: DDPHENO:0001354 ! aberrant basal disc formation

[Term]
id: DDPHENO:0000270
name: obsolete increased number of tubular mitochondria
def: "OBSOLETE. Quantitative increase in tubular mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000271
name: decreased number of mitochondria
def: "Quantitative reduction in mitochondria." [DDB:pg]
is_a: DDPHENO:0001234 ! aberrant mitochondrion organization

[Term]
id: DDPHENO:0000272
name: increased number of mitochondria
def: "Quantitative increase in mitochondria." [DDB:pg]
is_a: DDPHENO:0001234 ! aberrant mitochondrion organization

[Term]
id: DDPHENO:0000273
name: obsolete decreased SDF production
def: "OBSOLETE. Reduction in extent, amount or accumulation of SDF production." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000274
name: obsolete abolished SDF production
def: "OBSOLETE. Complete inability for SDF production." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000276
name: obsolete increased resistance to DNA-damaging agents
def: "OBSOLETE. Increased tolerance of the normal, usual, or expected events in the presence of DNA damaging agents." [DDB:pf]
synonym: "decreased sensitivity to DNA-damaging agents" EXACT []
is_obsolete: true

[Term]
id: DDPHENO:0000278
name: increased defense response to bacterium
def: "Increase in extent, amount, or degree of the defense response to bacterium." [DDB:pf]
is_a: DDPHENO:0000258 ! aberrant defense response to bacterium
created_by: pfey
creation_date: 2015-05-05T14:58:43Z

[Term]
id: DDPHENO:0000279
name: decreased defense response to bacterium
def: "Reduction in extent, amount, or degree for defense response to bacterium." [DDB:pf]
is_a: DDPHENO:0000258 ! aberrant defense response to bacterium
created_by: pfey
creation_date: 2015-05-05T14:59:45Z

[Term]
id: DDPHENO:0000280
name: aberrant defense response to fungus
def: "Deviation from the normal, usual, or expected events defense response to fungus." [DDB:pf]
synonym: "aberrant defense response to yeast" NARROW []
is_a: DDPHENO:0001505 ! aberrant cellular defense response
created_by: pfey
creation_date: 2015-05-05T16:05:13Z

[Term]
id: DDPHENO:0000281
name: obsolete aberrant infection rate by a yeast
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true
created_by: pfey
creation_date: 2015-05-05T16:06:20Z

[Term]
id: DDPHENO:0000282
name: increased defense response to fungus
def: "Increase in extent, amount, or degree of the defense response to fungus." [DDB:pf]
synonym: "increased defense response to yeast" NARROW []
is_a: DDPHENO:0000280 ! aberrant defense response to fungus
created_by: pfey
creation_date: 2015-05-05T16:07:54Z

[Term]
id: DDPHENO:0000283
name: decreased defense response to fungus
def: "Reduction in extent, amount, or degree for defense response to fungus." [DDB:pf]
synonym: "decreased defense response to yeast" NARROW []
is_a: DDPHENO:0000280 ! aberrant defense response to fungus
created_by: pfey
creation_date: 2015-05-05T16:08:09Z

[Term]
id: DDPHENO:0000284
name: aberrant defense response to Gram-positive bacterium
def: "Deviation from the normal, usual, or expected events during defense response to Gram-positive bacterium, often after infection." [DDB:pf, PMID:23664307]
synonym: "aberrant defense response to pathogenic Gram-positive bacterium" NARROW []
is_a: DDPHENO:0000258 ! aberrant defense response to bacterium
created_by: pfey
creation_date: 2015-05-05T16:38:31Z

[Term]
id: DDPHENO:0000285
name: increased defense response to Gram-positive bacterium
def: "Increase in extent, amount, or degree of the defense response to Gram-positive bacterium, often after infection." [DDB:pf]
synonym: "increased defense response to pathogenic Gram-positive bacterium" NARROW []
is_a: DDPHENO:0000278 ! increased defense response to bacterium
is_a: DDPHENO:0000284 ! aberrant defense response to Gram-positive bacterium
created_by: pfey
creation_date: 2015-05-05T16:42:05Z

[Term]
id: DDPHENO:0000286
name: decreased defense response to Gram-positive bacterium
def: "Reduction in extent, amount, or degree for defense response to Gram-positive bacterium, often after infection." [DDB:pf]
synonym: "decreased defense response to pathogenic Gram-positive bacterium" NARROW []
is_a: DDPHENO:0000279 ! decreased defense response to bacterium
is_a: DDPHENO:0000284 ! aberrant defense response to Gram-positive bacterium
created_by: pfey
creation_date: 2015-05-05T16:42:37Z

[Term]
id: DDPHENO:0000287
name: aberrant defense response to Gram-negative bacterium
def: "Deviation from the normal, usual, or expected events defense response to Gram-negative bacterium, often after infection." [DDB:pf, PMID:23664307]
synonym: "aberrant defense response to pathogenic Gram-negative bacterium" NARROW []
is_a: DDPHENO:0000258 ! aberrant defense response to bacterium
created_by: pfey
creation_date: 2015-05-05T16:48:58Z

[Term]
id: DDPHENO:0000288
name: increased defense response to Gram-negative bacterium
def: "Increase in extent, amount, or degree of the defense response to Gram-negative bacterium, often after infection." [DDB:pf]
synonym: "increased defense response to pathogenic Gram-negative bacterium" NARROW []
is_a: DDPHENO:0000278 ! increased defense response to bacterium
is_a: DDPHENO:0000287 ! aberrant defense response to Gram-negative bacterium
created_by: pfey
creation_date: 2015-05-05T16:49:27Z

[Term]
id: DDPHENO:0000289
name: decreased defense response to Gram-negative bacterium
def: "Reduction in extent, amount, or degree of the defense response to Gram-negative bacterium, often after infection." [DDB:pf]
synonym: "decreased defense response to pathogenic Gram-negative bacterium" NARROW []
is_a: DDPHENO:0000279 ! decreased defense response to bacterium
is_a: DDPHENO:0000287 ! aberrant defense response to Gram-negative bacterium
created_by: pfey
creation_date: 2015-05-05T16:49:39Z

[Term]
id: DDPHENO:0000290
name: abolished defense response to Gram-positive bacterium
def: "Complete inability for defense response to Gram-positive bacterium, often after infection." [DDB:pf]
synonym: "abolished defense response to pathogenic Gram-positive bacterium" NARROW []
is_a: DDPHENO:0000284 ! aberrant defense response to Gram-positive bacterium
is_a: DDPHENO:0000491 ! abolished defense response to bacterium
created_by: pfey
creation_date: 2015-05-05T16:57:55Z

[Term]
id: DDPHENO:0000291
name: abolished defense response to Gram-negative bacterium
def: "Complete inability for defense response to Gram-negative bacterium, often after infection." [DDB:pf]
synonym: "abolished defense response to pathogenic Gram-negative bacterium" NARROW []
is_a: DDPHENO:0000287 ! aberrant defense response to Gram-negative bacterium
is_a: DDPHENO:0000491 ! abolished defense response to bacterium
created_by: pfey
creation_date: 2015-05-05T16:58:28Z

[Term]
id: DDPHENO:0000292
name: obsolete decreased infection rate by Mycobacterium marinum
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true
created_by: pfey
creation_date: 2015-05-05T17:02:13Z

[Term]
id: DDPHENO:0000293
name: obsolete increased infection rate by Mycobacterium marinum
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true
created_by: pfey
creation_date: 2015-05-05T17:03:59Z

[Term]
id: DDPHENO:0000294
name: aberrant protein binding
def: "Deviation from the normal, usual, or expected binding of a protein." [DDB:pf]
is_a: DDPHENO:0001255 ! aberrant binding
created_by: pfey
creation_date: 2015-05-20T17:42:41Z

[Term]
id: DDPHENO:0000295
name: abolished protein binding
def: "Complete absence of protein binding." [DDB:pf]
is_a: DDPHENO:0000294 ! aberrant protein binding
created_by: pfey
creation_date: 2015-05-20T17:43:34Z

[Term]
id: DDPHENO:0000296
name: decreased protein binding
def: "A reduction in extent, amount, or degree of binding to a protein." [DDB:pf]
is_a: DDPHENO:0000294 ! aberrant protein binding
created_by: pfey
creation_date: 2015-05-20T17:44:30Z

[Term]
id: DDPHENO:0000297
name: increased protein binding
def: "Increased in extent, amount, or degree of binding a protein." [DDB:pf]
is_a: DDPHENO:0000294 ! aberrant protein binding
created_by: pfey
creation_date: 2015-05-20T17:44:44Z

[Term]
id: DDPHENO:0000298
name: aberrant lipid binding
def: "Deviation from the normal, usual, or expected binding a lipid." [DDB:pf]
is_a: DDPHENO:0001255 ! aberrant binding
created_by: pfey
creation_date: 2015-05-20T17:46:27Z

[Term]
id: DDPHENO:0000300
name: decreased gene expression
alt_id: DDPHENO:0000174
alt_id: DDPHENO:0000189
alt_id: DDPHENO:0000220
alt_id: DDPHENO:0000267
def: "Reduction in extent, amount, or degree of gene expression." [DDB:pg]
synonym: "merged_decreased expression of aggregation genes" NARROW [DDB:kp]
synonym: "merged_decreased expression of prespore genes" NARROW [DDB:kp]
synonym: "merged_decreased expression of prestalk genes" NARROW [DDB:kp]
synonym: "merged_decreased expression of spore genes" NARROW [DDB:kp]
is_a: DDPHENO:0001113 ! aberrant gene expression

[Term]
id: DDPHENO:0000301
name: increased gene expression
alt_id: DDPHENO:0000114
alt_id: DDPHENO:0000224
alt_id: DDPHENO:0000266
alt_id: DDPHENO:0000372
def: "Increase in extent, amount, or degree of gene expression." [DDB:pg]
synonym: "merged_increased discoidin level" NARROW [DDB:kp]
synonym: "merged_increased expression of post-aggregative genes" NARROW [DDB:kp]
synonym: "merged_increased expression of prespore genes" NARROW [DDB:kp]
synonym: "merged_increased expression of prestalk genes" NARROW [DDB:kp]
is_a: DDPHENO:0001113 ! aberrant gene expression

[Term]
id: DDPHENO:0000302
name: abolished vegetative growth
alt_id: DDPHENO:0000221
alt_id: DDPHENO:0000259
alt_id: DDPHENO:0000275
alt_id: DDPHENO:0000458
alt_id: DDPHENO:0001060
def: "Complete inability for cells to proliferate." [DDB:pg]
synonym: "abolished asexual reproduction" EXACT []
synonym: "abolished growth in acidic medium" NARROW []
synonym: "abolished growth in axenic medium" NARROW []
synonym: "abolished growth in suspension" NARROW []
synonym: "abolished growth on bacterial plates" NARROW []
synonym: "inviable" RELATED []
is_a: DDPHENO:0001084 ! aberrant vegetative growth

[Term]
id: DDPHENO:0000304
name: increased membrane ruffling
def: "Increase in extent, amount, or degree of membrane ruffling." [DDB:pg]
synonym: "increased ruffle assembly" EXACT []
is_a: DDPHENO:0000042 ! aberrant membrane ruffling

[Term]
id: DDPHENO:0000305
name: obsolete abolished down-regulation of growth phase genes
def: "OBSOLETE. Complete inability for down-regulation of growth phase genes." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000306
name: aberrant cell migration to prestalk region
def: "Deviation from the normal, usual, or expected cell migration to the prestalk region." [DDB:pf]
synonym: "aberrant sorting to prestalk region" EXACT []
is_a: DDPHENO:0001014 ! aberrant slug development
created_by: pfey
creation_date: 2015-06-16T17:41:25Z

[Term]
id: DDPHENO:0000307
name: obsolete abolished SDF-1 production
def: "OBSOLETE. Complete inability for SDF-1 production." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-06-17T14:01:18Z

[Term]
id: DDPHENO:0000308
name: obsolete abolished SDF-2 production
def: "OBSOLETE. Complete inability for SDF-2 production." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-06-17T14:01:46Z

[Term]
id: DDPHENO:0000309
name: obsolete decreased SDF-1 production
def: "OBSOLETE. Reduction in extent, amount or accumulation of SDF-1 production." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-06-17T14:02:06Z

[Term]
id: DDPHENO:0000310
name: obsolete decreased SDF-2 production
def: "OBSOLETE. Reduction in extent, amount or accumulation of SDF-2 production." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-06-17T14:03:53Z

[Term]
id: DDPHENO:0000311
name: aberrant MPBD level
def: "Deviation from the normal, usual, or expected during MPBD biosynthesis, a polyketide." [DDB:pf]
synonym: "aberrant 4-methyl5-pentylbenzene-1,3 diol production" EXACT []
synonym: "aberrant MPBD biosynthesis" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2015-06-17T14:37:07Z

[Term]
id: DDPHENO:0000312
name: abolished MPBD level
def: "Complete inability for the biosynthesis of MPBD, a polyketide." [DDB:pf]
synonym: "abolished 4-methyl5-pentylbenzene-1,3-diol production" EXACT []
synonym: "abolished MPBD biosynthesis" EXACT []
is_a: DDPHENO:0000311 ! aberrant MPBD level
created_by: pfey
creation_date: 2015-06-17T14:39:34Z

[Term]
id: DDPHENO:0000313
name: decreased MPBD level
def: "Reduction in extent, amount, or degree of MPBD biosynthesis, a polyketide." [DDB:pf]
synonym: "decreased 4-methyl5-pentylbenzene-1,3 diol production" EXACT []
synonym: "decreased MPBD biosynthesis" EXACT []
is_a: DDPHENO:0000311 ! aberrant MPBD level
created_by: pfey
creation_date: 2015-06-17T14:40:21Z

[Term]
id: DDPHENO:0000314
name: aberrant polyketide metabolic process
def: "Deviation from the normal, usual, or expected during the polyketide metabolic process." [DDB:pf]
synonym: "aberrant response to 4-methyl5-pentylbenzene-1,3 diol (MPBD)" NARROW []
is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus
created_by: pfey
creation_date: 2015-06-17T17:18:33Z

[Term]
id: DDPHENO:0000315
name: abolished polyketide metabolic process
def: "Complete inability for polyketide metabolic process." [DDB:pf]
synonym: "abolished response to 4-methyl5-pentylbenzene-1,3 diol (MPBD)" NARROW []
is_a: DDPHENO:0000314 ! aberrant polyketide metabolic process
is_a: DDPHENO:0000693 ! abolished response to biotic stimulus
created_by: pfey
creation_date: 2015-06-17T17:20:55Z

[Term]
id: DDPHENO:0000316
name: obsolete aberrant response to SDF-1
def: "OBSOLETE. Deviation from the normal, usual, or expected events during response to SDF-1." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-06-17T17:27:25Z

[Term]
id: DDPHENO:0000317
name: obsolete abolished response to SDF-1
def: "OBSOLETE. Complete inability for response to SDF-1." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2015-06-17T17:29:11Z

[Term]
id: DDPHENO:0000318
name: abolished development of tipped mound
def: "Complete inability to form a tipped mound during development." [DDB:pf]
synonym: "abolished sorocarp development of tipped mound" EXACT []
synonym: "abolished tip formation" RELATED []
is_a: DDPHENO:0001431 ! aberrant development of tipped mound
created_by: pfey
creation_date: 2015-10-08T17:23:04Z

[Term]
id: DDPHENO:0000320
name: aberrant polysaccharide binding
def: "Deviation from the normal, usual, or expected binding a polysaccharide." [DDB:pf]
is_a: DDPHENO:0001255 ! aberrant binding
created_by: pfey
creation_date: 2015-12-17T17:14:53Z

[Term]
id: DDPHENO:0000321
name: aberrant cellulose binding
def: "Deviation from the normal, usual, or expected binding of cellulose." [DDB:pf]
is_a: DDPHENO:0000320 ! aberrant polysaccharide binding
created_by: pfey
creation_date: 2015-12-17T17:15:32Z

[Term]
id: DDPHENO:0000322
name: abolished cellulose binding
def: "Complete absence of cellulose binding." [DDB:pf]
is_a: DDPHENO:0000321 ! aberrant cellulose binding
created_by: pfey
creation_date: 2015-12-17T17:16:25Z

[Term]
id: DDPHENO:0000323
name: decreased cellulose binding
def: "A reduction in extent, amount, or degree of binding to cellulose." [DDB:pf]
is_a: DDPHENO:0000321 ! aberrant cellulose binding
created_by: pfey
creation_date: 2015-12-17T17:16:44Z

[Term]
id: DDPHENO:0000324
name: aberrant cyclic nucleotide binding
def: "Deviation from the normal, usual, or expected binding of a cyclic nucleotide." [DDB:pf]
is_a: DDPHENO:0000327 ! aberrant small molecule binding
created_by: pfey
creation_date: 2015-12-17T17:18:19Z

[Term]
id: DDPHENO:0000325
name: decreased lipid binding
def: "A reduction in extent, amount, or degree of binding to a lipid." [DDB:pf]
is_a: DDPHENO:0000298 ! aberrant lipid binding
created_by: pfey
creation_date: 2015-12-17T17:50:09Z

[Term]
id: DDPHENO:0000326
name: abolished lipid binding
def: "Complete absence of lipid binding." [DDB:pf]
is_a: DDPHENO:0000298 ! aberrant lipid binding
created_by: pfey
creation_date: 2015-12-17T17:50:52Z

[Term]
id: DDPHENO:0000327
name: aberrant small molecule binding
def: "Deviation from the normal, usual, or expected binding a small molecule." [DDB:pf]
comment: Small molecules include monosaccharides but exclude disaccharides and polysaccharides; includes organic cyclic compounds and single amino acids.
is_a: DDPHENO:0001255 ! aberrant binding
created_by: pfey
creation_date: 2015-12-17T17:52:38Z

[Term]
id: DDPHENO:0000328
name: abolished small molecule binding
def: "Complete absence of small molecule binding." [DDB:pf]
comment: Small molecules include monosaccharides but exclude disaccharides and polysaccharides; includes organic cyclic compounds and single amino acids.
is_a: DDPHENO:0000327 ! aberrant small molecule binding
created_by: pfey
creation_date: 2015-12-17T17:53:02Z

[Term]
id: DDPHENO:0000329
name: decreased small molecule binding
def: "A reduction in extent, amount, or degree of binding to a small molecule." [DDB:pf]
comment: Small molecules include monosaccharides but exclude disaccharides and polysaccharides; includes organic cyclic compounds and single amino acids.
is_a: DDPHENO:0000327 ! aberrant small molecule binding
created_by: pfey
creation_date: 2015-12-17T17:53:44Z

[Term]
id: DDPHENO:0000330
name: abolished cAMP binding
def: "Complete absence of cAMP binding." [DDB:pf]
is_a: DDPHENO:0000324 ! aberrant cyclic nucleotide binding
is_a: DDPHENO:0000328 ! abolished small molecule binding
created_by: pfey
creation_date: 2016-04-21T16:35:28Z

[Term]
id: DDPHENO:0000331
name: aberrant folic acid binding
def: "Deviation from the normal, usual, or expected binding to folic acid." [DDB:pf]
is_a: DDPHENO:0000327 ! aberrant small molecule binding
created_by: pfey
creation_date: 2016-04-21T16:37:34Z

[Term]
id: DDPHENO:0000332
name: decreased folic acid binding
def: "A reduction in extent, amount, or degree of binding to folic acid." [DDB:pf]
is_a: DDPHENO:0000329 ! decreased small molecule binding
is_a: DDPHENO:0000331 ! aberrant folic acid binding
created_by: pfey
creation_date: 2016-04-21T16:39:46Z

[Term]
id: DDPHENO:0000333
name: increased folic acid binding
def: "Increased in extent, amount, or degree of binding to folic acid." [DDB:pf]
is_a: DDPHENO:0000331 ! aberrant folic acid binding
created_by: pfey
creation_date: 2016-04-21T16:40:08Z

[Term]
id: DDPHENO:0000334
name: abolished folic acid binding
def: "Complete absence of folic acid binding." [DDB:pf]
is_a: DDPHENO:0000328 ! abolished small molecule binding
is_a: DDPHENO:0000331 ! aberrant folic acid binding
created_by: pfey
creation_date: 2016-04-21T16:42:34Z

[Term]
id: DDPHENO:0000335
name: obsolete aberrant electrotaxis
def: "OBSOLETE. Deviation from the normal, usual, or expected events during the locomotory response to an electrical field." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2016-06-14T12:24:22Z

[Term]
id: DDPHENO:0000336
name: obsolete decreased electrotaxis
def: "Obsolete Reduction in extent, amount, or degree of electrotaxis rate during the locomotory response to an electrical field." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2016-06-14T12:26:21Z

[Term]
id: DDPHENO:0000337
name: obsolete increased electrotaxis
def: "OBSOLETE. Increase in extent, amount, or degree of electrotaxis rate during the locomotory response to an electrical field." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2016-06-14T12:26:37Z

[Term]
id: DDPHENO:0000338
name: obsolete abolished electrotaxis
def: "OBSOLETE. Complete inability for electrotaxis in response to an electrical field." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2016-06-14T12:26:51Z

[Term]
id: DDPHENO:0000339
name: obsolete aberrant response to SDF-2
def: "OBSOLETE. Deviation from the normal, usual, or expected events during response to SDF-2." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2016-07-18T10:38:21Z

[Term]
id: DDPHENO:0000340
name: obsolete abolished response to SDF-2
def: "OBSOLETE. Complete inability for response to SDF-2." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2016-07-18T10:39:38Z

[Term]
id: DDPHENO:0000341
name: obsolete aberrant membrane organization during endocytosis
def: "OBSOLETE. Deviation from the normal, usual, or expected plasma membrane organization during endocytosis." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2016-09-07T17:43:13Z

[Term]
id: DDPHENO:0000342
name: decreased plasma membrane organization
def: "Decrease from the normal, usual, or expected plasma membrane organization." [DDB:pf]
is_a: DDPHENO:0000039 ! aberrant plasma membrane organization
created_by: pfey
creation_date: 2016-09-07T17:44:39Z

[Term]
id: DDPHENO:0000343
name: abolished activation of GTPase activity
def: "Complete inability for activation of GTPase activity." [DDB:pf]
is_a: DDPHENO:0001311 ! aberrant activation of GTPase activity
created_by: pfey
creation_date: 2016-10-07T13:24:37Z

[Term]
id: DDPHENO:0000344
name: decreased activation of GTPase activity
def: "Reduction in extent, amount, or degree of activation GTPase activity." [DDB:pf]
is_a: DDPHENO:0001311 ! aberrant activation of GTPase activity
created_by: pfey
creation_date: 2016-10-07T13:25:29Z

[Term]
id: DDPHENO:0000345
name: increased activation of GTPase activity
def: "Increase in extent, amount, or degree of activation of GTPase activity." [DDB:pf]
is_a: DDPHENO:0001311 ! aberrant activation of GTPase activity
created_by: pfey
creation_date: 2016-10-07T13:25:54Z

[Term]
id: DDPHENO:0000346
name: decreased protein kinase activity
def: "Reduction in extent, amount, or degree of protein kinase activity." [DDB:pf]
is_a: DDPHENO:0001257 ! decreased catalytic activity
created_by: pfey
creation_date: 2016-10-10T17:14:11Z

[Term]
id: DDPHENO:0000347
name: abolished protein kinase activity
def: "Complete absence of protein kinase activity." [DDB:pf]
is_a: DDPHENO:0001289 ! abolished catalytic activity
created_by: pfey
creation_date: 2016-10-10T17:17:41Z

[Term]
id: DDPHENO:0000348
name: increased protein kinase activity
def: "Increase in extent, amount, or degree of protein kinase activity." [DDB:pf]
is_a: DDPHENO:0001256 ! increased catalytic activity
created_by: pfey
creation_date: 2016-10-10T17:18:44Z

[Term]
id: DDPHENO:0000349
name: aberrant calcium-mediated signaling
def: "Deviation from the normal, usual, or expected events during calcium signaling." [DDB:pf]
synonym: "aberrant Ca2+ signaling" EXACT []
is_a: DDPHENO:0001118 ! aberrant signal transduction
created_by: pfey
creation_date: 2016-10-11T12:46:12Z

[Term]
id: DDPHENO:0000350
name: aberrant macropinocytosis
def: "Deviation from the normal, usual, or expected events during macropinocytosis." [DDB:pf]
is_a: DDPHENO:0001007 ! aberrant pinocytosis
created_by: pfey
creation_date: 2016-10-11T13:11:24Z

[Term]
id: DDPHENO:0000351
name: abolished macropinocytosis
def: "Complete inability to perform macropinocytosis." [DDB:pf]
is_a: DDPHENO:0000350 ! aberrant macropinocytosis
created_by: pfey
creation_date: 2016-10-11T13:13:56Z

[Term]
id: DDPHENO:0000352
name: decreased macropinocytosis
def: "Reduction in extent, amount, or degree of macropinocytosis." [DDB:pf]
is_a: DDPHENO:0000350 ! aberrant macropinocytosis
created_by: pfey
creation_date: 2016-10-11T13:14:51Z

[Term]
id: DDPHENO:0000353
name: aberrant endosomal transport
def: "Deviation from the normal, usual, or expected events during endosomal transport." [DDB:pf]
is_a: DDPHENO:0001047 ! aberrant transport
created_by: pfey
creation_date: 2017-02-08T15:22:57Z

[Term]
id: DDPHENO:0000354
name: aberrant endocytic recycling
def: "Deviation from the normal, usual, or expected events during endocytic recycling." [DDB:pf]
synonym: "aberrant retrograde transport of endocytic vesicles" RELATED []
is_a: DDPHENO:0000353 ! aberrant endosomal transport
created_by: pfey
creation_date: 2017-02-08T15:26:07Z

[Term]
id: DDPHENO:0000355
name: abolished endocytic recycling
def: "Complete inability of endocytic recycling." [DDB:pf]
synonym: "abolished retrograde transport of endocytic vesicles" RELATED []
is_a: DDPHENO:0000354 ! aberrant endocytic recycling
created_by: pfey
creation_date: 2017-02-08T15:27:20Z

[Term]
id: DDPHENO:0000356
name: decreased endocytic recycling
def: "Reduction in extent, amount, or degree of endocytic recycling." [DDB:pf]
synonym: "decreased retrograde transport of endocytic vesicles" RELATED []
is_a: DDPHENO:0000354 ! aberrant endocytic recycling
created_by: pfey
creation_date: 2017-02-08T15:29:59Z

[Term]
id: DDPHENO:0000357
name: increased endocytic recycling
def: "Increase in extent, amount, or degree of endocytic recycling." [DDB:pf]
synonym: "increased retrograde transport of endocytic vesicles" RELATED []
is_a: DDPHENO:0000354 ! aberrant endocytic recycling
created_by: pfey
creation_date: 2017-02-08T15:31:07Z

[Term]
id: DDPHENO:0000358
name: aberrant response to cAMP
def: "Deviation from the normal, usual, or expected events during the response to cAMP." [DDB:pf]
is_a: DDPHENO:0001038 ! aberrant extracellular cAMP signaling
created_by: pfey
creation_date: 2017-02-24T10:45:56Z

[Term]
id: DDPHENO:0000359
name: increased response to cAMP
def: "Increase in extent, amount, or degree of response to cAMP." [DDB:pf]
is_a: DDPHENO:0000358 ! aberrant response to cAMP
created_by: pfey
creation_date: 2017-02-24T10:46:56Z

[Term]
id: DDPHENO:0000360
name: decreased response to cAMP
def: "Reduction in the response to cAMP." [DDB:pf]
is_a: DDPHENO:0000358 ! aberrant response to cAMP
created_by: pfey
creation_date: 2017-02-24T10:47:13Z

[Term]
id: DDPHENO:0000361
name: abolished response to cAMP
def: "Complete inability to respond to cAMP." [DDB:pf]
is_a: DDPHENO:0000358 ! aberrant response to cAMP
created_by: pfey
creation_date: 2017-02-24T10:48:18Z

[Term]
id: DDPHENO:0000362
name: aberrant response to nocodazole
def: "Deviation from the normal, usual, or expected events during the response to nocodazole." [DDB:pf]
is_a: DDPHENO:0000040 ! aberrant response to chemical
created_by: pfey
creation_date: 2017-03-07T16:39:49Z

[Term]
id: DDPHENO:0000363
name: increased resistance to nocodazole
def: "Increase in extent, amount, or degree of resistance to nocodazole." [DDB:pf]
is_a: DDPHENO:0000362 ! aberrant response to nocodazole
created_by: pfey
creation_date: 2017-03-07T16:41:38Z

[Term]
id: DDPHENO:0000364
name: increased macropinocytosis
def: "Increase in extent, amount, or degree of macropinocytosis." [DDB:pf]
is_a: DDPHENO:0000350 ! aberrant macropinocytosis
created_by: pfey
creation_date: 2017-03-13T10:24:42Z

[Term]
id: DDPHENO:0000365
name: aberrant prestalk gene expression
def: "Deviation from the normal, usual, or expected expression of prestalk genes." [DDB:pf]
synonym: "aberrant prestalk cell specific gene expression" EXACT []
is_a: DDPHENO:0001113 ! aberrant gene expression
created_by: pfey
creation_date: 2017-03-23T09:52:00Z

[Term]
id: DDPHENO:0000366
name: precocious prestalk gene expression
def: "Early onset or faster progression in the expression of prestalk genes." [DDB:pf]
synonym: "precocious prestalk cell specific gene expression" EXACT []
is_a: DDPHENO:0000365 ! aberrant prestalk gene expression
is_a: DDPHENO:0001116 ! precocious gene expression
created_by: pfey
creation_date: 2017-03-23T09:53:39Z

[Term]
id: DDPHENO:0000367
name: obsolete mislocalized prestalk gene expression
def: "OBSOLETE. Prestalk gene expression occurring in an abnormal position or in an unusual manner or form." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2017-03-23T13:29:35Z

[Term]
id: DDPHENO:0000368
name: delayed prestalk gene expression
def: "Late onset or slower progression in the expression of prestalk genes." [DDB:pf]
synonym: "delayed prestalk cell specific gene expression" EXACT []
is_a: DDPHENO:0000365 ! aberrant prestalk gene expression
is_a: DDPHENO:0001115 ! delayed gene expression
created_by: pfey
creation_date: 2017-03-23T14:54:09Z

[Term]
id: DDPHENO:0000369
name: decreased prestalk gene expression
def: "Reduction in extent, amount, or degree of prestalk gene expression." [DDB:pf]
synonym: "decreased prestalk cell specific gene expression" EXACT []
is_a: DDPHENO:0000300 ! decreased gene expression
is_a: DDPHENO:0000365 ! aberrant prestalk gene expression
created_by: pfey
creation_date: 2017-03-23T14:54:56Z

[Term]
id: DDPHENO:0000370
name: aberrant prespore gene expression
def: "Deviation from the normal, usual, or expected expression of prespore genes." [DDB:pf]
synonym: "aberrant prespore cell specific gene expression" EXACT []
is_a: DDPHENO:0001113 ! aberrant gene expression
created_by: pfey
creation_date: 2017-03-23T15:35:42Z

[Term]
id: DDPHENO:0000371
name: decreased prespore gene expression
def: "Reduction in extent, amount, or degree of prespore gene expression." [DDB:pf]
synonym: "decreased prespore cell specific gene expression" EXACT []
is_a: DDPHENO:0000300 ! decreased gene expression
is_a: DDPHENO:0000370 ! aberrant prespore gene expression
created_by: pfey
creation_date: 2017-03-23T15:36:45Z

[Term]
id: DDPHENO:0000375
name: delayed prespore gene expression
def: "Late onset or slower progression in the expression of prespore genes." [DDB:pf]
synonym: "delayed prespore cell specific gene expression" EXACT []
is_a: DDPHENO:0000370 ! aberrant prespore gene expression
is_a: DDPHENO:0001115 ! delayed gene expression
created_by: pfey
creation_date: 2017-03-23T15:38:40Z

[Term]
id: DDPHENO:0000376
name: abolished filopodium formation
def: "Complete inability to form filopodia." [DDB:pf]
synonym: "abolished filopodium assembly" EXACT []
is_a: DDPHENO:0001028 ! aberrant filopodium formation

[Term]
id: DDPHENO:0000377
name: increased filopodium formation
def: "Increase in extent, amount, or degree of formation of filopodia." [DDB:pg]
synonym: "increased filopodium assembly" EXACT []
is_a: DDPHENO:0001028 ! aberrant filopodium formation

[Term]
id: DDPHENO:0000378
name: decreased lateral pseudopodium retraction
def: "Reduction in extent, amount, or degree of suppression or retraction of lateral pseudopods." [DD:pg]
is_a: DDPHENO:0000477 ! aberrant lateral pseudopodium formation

[Term]
id: DDPHENO:0000379
name: decreased vegetative cell size
def: "Reduction in relative or proportionate dimensions of the vegetative cell." [DDB:pf]
synonym: "decreased vegetative amoebae size" EXACT []
xref: PMID:18366659 "DDANAT:0000002"
is_a: DDPHENO:0000236 ! aberrant cell morphology

[Term]
id: DDPHENO:0000381
name: decreased resistance to TMB-8
def: "Decreased tolerance of the normal, usual, or expected events towards TMB-8." [DDB:pf]
synonym: "increased sensitivity to 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate" EXACT []
is_a: DDPHENO:0000040 ! aberrant response to chemical

[Term]
id: DDPHENO:0000382
name: obsolete aberrant morphology
def: "OBSOLETE. Deviation from the normal, usual, or expected events during morphogenesis." [DDB:kp]
is_obsolete: true

[Term]
id: DDPHENO:0000383
name: decreased stalk length
def: "Having a relative short stalk." [DDB:pg]
synonym: "short stalk" EXACT []
xref: PATO:0000574
is_a: DDPHENO:0000510 ! aberrant stalk morphogenesis

[Term]
id: DDPHENO:0000384
name: aberrant sorus morphology
def: "Deviation from the normal, usual, or expected morphology of the sorus." [DDB:pg]
synonym: "aberrant spore head morphology" EXACT []
is_a: DDPHENO:0000009 ! aberrant fruiting body morphology

[Term]
id: DDPHENO:0000385
name: abolished cytokinesis
def: "Complete inability for cytokinesis." [DDB:pg]
is_a: DDPHENO:0000149 ! aberrant cytokinesis

[Term]
id: DDPHENO:0000387
name: abolished prespore cell division
def: "Complete inability for division of prespore cells." [DDB:pg]
is_a: DDPHENO:0001014 ! aberrant slug development

[Term]
id: DDPHENO:0000388
name: obsolete abolished vacuolation
def: "OBSOLETE. Complete inability for vacuolation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000389
name: increased sorus size
def: "Increase in relative or proportionate dimensions of the sorus." [DDB:pg]
synonym: "large sori" EXACT []
is_a: DDPHENO:0000384 ! aberrant sorus morphology

[Term]
id: DDPHENO:0000390
name: aberrant sorus color
def: "Deviation from the normal, usual, or expected sorus color." [DDB:pf]
is_a: DDPHENO:0000513 ! aberrant sporulation

[Term]
id: DDPHENO:0000391
name: obsolete partial suppression of tagB mutation
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0000392
name: decreased establishment of cell polarity
def: "Reduction in extent, amount, or degree of cell polarity establishment." [DDB:pg]
synonym: "decreased cell polarity" EXACT []
is_a: DDPHENO:0001029 ! aberrant establishment or maintenance of cell polarity

[Term]
id: DDPHENO:0000393
name: decreased cell-substrate adhesion
def: "Reduction in extent, amount, or degree of cell-substrate adhesion." [DDB:pg]
synonym: "decreased substrate adhesion" RELATED []
is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion

[Term]
id: DDPHENO:0000394
name: decreased growth rate
alt_id: DDPHENO:0000202
alt_id: DDPHENO:0000373
alt_id: DDPHENO:0000396
alt_id: DDPHENO:0000416
alt_id: DDPHENO:0000417
alt_id: DDPHENO:0000435
alt_id: DDPHENO:0000436
alt_id: DDPHENO:0000467
alt_id: DDPHENO:0000511
alt_id: DDPHENO:0000534
alt_id: DDPHENO:0001096
def: "Reduction in extent, amount, or degree of cell proliferation." [DDB:pf]
synonym: "decreased asexual reproduction" EXACT []
synonym: "decreased growth rate in bacterial suspension" NARROW []
synonym: "decreased growth rate in liquid medium on solid surfaces" NARROW []
synonym: "decreased growth rate in suspension" NARROW []
synonym: "decreased growth rate in suspension at low temperature" NARROW []
synonym: "decreased growth rate on bacterial plates" NARROW []
synonym: "decreased growth rate under Ca2+ stress" NARROW []
synonym: "decreased growth rates on solid surfaces" NARROW []
synonym: "merged_decreased growth rate at low cell density" NARROW []
synonym: "merged_decreased growth rate in suspension in the presence of lithium" NARROW []
synonym: "merged_decreased growth rate in the presence of gossypol" NARROW []
synonym: "merged_decreased growth rate in the presence of ion chelators" NARROW []
is_a: DDPHENO:0001084 ! aberrant vegetative growth

[Term]
id: DDPHENO:0000395
name: obsolete decreased activation of protein kinase B
def: "OBSOLETE. Reduction in extent, amount or degree of activation of protein kinase B." [DDB:pg]
comment: Not sure this is legitimate. See SF for an item on PKB; I think it's a gee product.
is_obsolete: true

[Term]
id: DDPHENO:0000397
name: aberrant cytoskeleton organization
def: "Deviation from the normal, usual, or expected events during cytoskeleton organization." [DDB:pg]
is_a: DDPHENO:0001002 ! aberrant organelle morphology

[Term]
id: DDPHENO:0000398
name: obsolete no synthetic interaction observed between rasS and gefB
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0000399
name: decreased rate of endocytosis
def: "Reduction in extent, amount, or degree of endocytosis." [DDB:pg]
is_a: DDPHENO:0000090 ! aberrant endocytosis

[Term]
id: DDPHENO:0000400
name: increased chemotaxis rate
def: "Increase in extent, amount, or degree of chemotaxis rate during the locomotory response to a chemical concentration gradient." [DDB:kp]
is_a: DDPHENO:0000116 ! increased cell motility
is_a: DDPHENO:0001122 ! aberrant chemotaxis
is_a: DDPHENO:0001129 ! increased taxis

[Term]
id: DDPHENO:0000401
name: increased resistance to cisplatin
def: "Increase in extent, amount, or degree of resistance to cisplatin." [DDB:pf]
is_a: DDPHENO:0001456 ! aberrant response to cisplatin

[Term]
id: DDPHENO:0000402
name: obsolete increased intracellular cAMP level
def: "OBSOLETE. Increase in extent, amount, or degree of intracellular cAMP level." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000403
name: increased prestalk gene expression
def: "Increase in extent, amount, or degree of expression of prestalk genes." [DDB:pf]
synonym: "increased prestalk cell specific gene expression" EXACT []
is_a: DDPHENO:0000301 ! increased gene expression
is_a: DDPHENO:0000365 ! aberrant prestalk gene expression
created_by: pfey
creation_date: 2017-03-23T15:39:41Z

[Term]
id: DDPHENO:0000404
name: increased prespore gene expression
def: "Increase in extent, amount, or degree of expression of prespore genes." [DDB:pf]
synonym: "increased prespore gene cell specific expression" EXACT []
is_a: DDPHENO:0000301 ! increased gene expression
is_a: DDPHENO:0000370 ! aberrant prespore gene expression
created_by: pfey
creation_date: 2017-03-23T15:54:24Z

[Term]
id: DDPHENO:0000405
name: increased phagocytosis
def: "Increase in extent, amount, or degree of phagocytosis." [DDB:pg]
is_a: DDPHENO:0001006 ! aberrant phagocytosis

[Term]
id: DDPHENO:0000406
name: increased vegetative cell size
def: "Increase in relative or proportionate dimensions of the vegetative cell." [DDB:pf]
synonym: "increased vegetative amoebae size" EXACT []
xref: PMID:18366659 "DDANAT:0000002"
is_a: DDPHENO:0000236 ! aberrant cell morphology

[Term]
id: DDPHENO:0000407
name: obsolete decreased chemoattractant-mediated F-actin polymerization
def: "OBSOLETE. Reduction in extent, amount or degree of chemoattractant-mediated F-actin polymerization." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000408
name: increased resistance to carboplatin
def: "Increase in extent, amount, or degree of resistance to carboplatin." [DDB:pf]
is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus

[Term]
id: DDPHENO:0000409
name: decreased resistance to carboplatin
def: "Decreased tolerance of the normal, usual, or expected events towards carboplatin." [DDB:pf]
is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus

[Term]
id: DDPHENO:0000410
name: decreased resistance to cisplatin
def: "Decreased tolerance of the normal, usual, or expected events towards cisplatin." [DDB:pf]
is_a: DDPHENO:0001456 ! aberrant response to cisplatin

[Term]
id: DDPHENO:0000411
name: increased resistance to heat
def: "Increased tolerance of the normal, usual, or expected events towards heat." [DDB:pf]
synonym: "increased resistance to heat shock" NARROW []
is_a: DDPHENO:0001035 ! aberrant response to heat

[Term]
id: DDPHENO:0000412
name: aberrant cell-cell adhesion
def: "Deviation from the normal, usual, or expected events during cell-cell adhesion." [DDB:pg]
is_a: DDPHENO:0001044 ! aberrant cell adhesion

[Term]
id: DDPHENO:0000413
name: aberrant microtubule cytoskeleton organization
def: "Deviation from the normal, usual, or expected events during organization of the microtubule cytoskeleton." [DDB:pg]
is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization

[Term]
id: DDPHENO:0000414
name: decreased resistance to heat
def: "Decreased tolerance of the normal, usual, or expected events towards heat." [DDB:pf]
synonym: "decreased resistance to heat shock" NARROW []
is_a: DDPHENO:0001035 ! aberrant response to heat

[Term]
id: DDPHENO:0000415
name: obsolete mislocalized prespore gene expression
def: "OBSOLETE. Prespore gene expression occurring in an abnormal position or in an unusual manner or form." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2017-03-23T15:55:17Z

[Term]
id: DDPHENO:0000420
name: obsolete decreased cAMP-induced Ca2+ influx
def: "OBSOLETE. Reduction in extent, amount or degree of cAMP-induced Ca2+ influx." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0000421
name: obsolete delayed cAMP-induced Ca2+ influx
def: "OBSOLETE. Late onset or slower progression for cAMP-induced Ca2+ influx." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0000422
name: obsolete decreased Ca2+-induced Ca2+ influx
def: "OBSOLETE. Reduction in extent, amount or degree of Ca2+ induced Ca2+ influx." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0000423
name: obsolete decreased infection rate by Legionella pneumophila
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0000424
name: abolished sporulation
def: "Complete inability for sporulation." [DDB:pg]
synonym: "abolished spore differentiation" EXACT []
is_a: DDPHENO:0000513 ! aberrant sporulation

[Term]
id: DDPHENO:0000425
name: decreased resistance to hydrogen peroxide
def: "Reduction in extent, amount, or degree of the resistance to hydrogen peroxide." [DDB:pf]
synonym: "decreased resistance to H2O2" EXACT []
is_a: DDPHENO:0000040 ! aberrant response to chemical

[Term]
id: DDPHENO:0000426
name: aberrant response to UV
def: "Deviation from the normal, usual, or expected events during the response to UV light." [DDB:pf]
synonym: "aberrant response to UV light" EXACT []
is_a: DDPHENO:0001034 ! aberrant cellular response to stress

[Term]
id: DDPHENO:0000427
name: decreased resistance to mitomycin C
def: "Decreased tolerance of the normal, usual, or expected events towards mitomycin C (MMC)." [DDB:pf]
synonym: "decreased resistance to MMC" EXACT []
is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus

[Term]
id: DDPHENO:0000428
name: decreased fatty acid level
def: "Reduction in extent, amount or accumulation of fatty acid." [DDB:pg]
synonym: "" RELATED []
synonym: "decreased fatty acid accumulation" RELATED []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0000429
name: aberrant vesicle coat assembly
def: "Deviation from the normal, usual, or expected process of vesicle coat assembly." [DDB:pg]
synonym: "aberrant vesicle coating" EXACT []
is_a: DDPHENO:0001043 ! aberrant organelle organization

[Term]
id: DDPHENO:0000430
name: decreased pinocytosis
def: "Reduction in extent, amount, or degree of pinocytosis." [DDD:pg]
is_a: DDPHENO:0001007 ! aberrant pinocytosis

[Term]
id: DDPHENO:0000431
name: mitotic G1 phase arrest
def: "The G1 phase in the mitotic cell cycle cannot complete." [DDB:pf]
synonym: "G1 phase mitotic cell cycle arrest" EXACT []
is_a: DDPHENO:0001418 ! aberrant cell cycle

[Term]
id: DDPHENO:0000432
name: aberrant glycogen metabolism
def: "Deviation from the normal, usual, or expected events during glycogen metabolism." [DDB:pg]
synonym: "aberrant glycogen metabolic process" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0000433
name: increased secretion of lysosomal enzymes
def: "Increase in extent, amount, or degree of secretion of lysosomal enzymes." [DDB:pf]
is_a: DDPHENO:0001232 ! increased protein secretion

[Term]
id: DDPHENO:0000434
name: aberrant pinosome maturation
def: "Deviation from the normal, usual, or expected events during pinosome maturation." [DDB:pf]
is_a: DDPHENO:0001007 ! aberrant pinocytosis

[Term]
id: DDPHENO:0000437
name: decreased actin nucleation
def: "Reduction in extent, amount, or degree of actin nucleation." [DDB:pg]
synonym: "decreased actin nucleation on plasma membranes" NARROW []
is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization

[Term]
id: DDPHENO:0000438
name: abolished uracil biosynthetic process
def: "Complete inability to produce uracil." [DDB:pf]
synonym: "uracil auxotroph" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
is_a: DDPHENO:0001034 ! aberrant cellular response to stress

[Term]
id: DDPHENO:0000439
name: increased resistance to 5-Fluoroorotic acid
def: "Increase in extent, amount, or degree of resistance to 5-Fluoroorotic acid." [DDB:pf]
synonym: "increased resistance to 5-FOA" EXACT []
is_a: DDPHENO:0000040 ! aberrant response to chemical

[Term]
id: DDPHENO:0000440
name: abolished thymidine biosynthetic process
def: "Complete inability to produce thymidine." [DDB:pf]
synonym: "thymidine auxotroph" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
is_a: DDPHENO:0001034 ! aberrant cellular response to stress

[Term]
id: DDPHENO:0000441
name: obsolete increased extracellular of CF50 level
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0000442
name: obsolete increased extracellular counting factor component(s) level
def: "OBSOLETE. Increase in extent, amount, or degree of counting factr component level." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000443
name: decreased secretion of lysosomal enzymes
def: "Reduction in extent, amount, or degree of secretion of lysosomal enzymes." [DDB:pf]
is_a: DDPHENO:0001233 ! decreased protein secretion

[Term]
id: DDPHENO:0000444
name: obsolete increased intracellular counting factor component(s) level
def: "OBSOLETE. Increase in extent, amount, or degree of intracellular counting factor (CF) level." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000445
name: increased slug migration
def: "Increase in extent, amount, or degree of migration of slugs." [DDB:pg]
synonym: "increased migratory slug locomotion" EXACT []
synonym: "slugger" NARROW []
is_a: DDPHENO:0001077 ! aberrant slug migration

[Term]
id: DDPHENO:0000446
name: aberrant mound color
def: "Deviation from the normal, usual, or expected mound color." [DDB:pg]
synonym: "aberrant aggregate color" EXACT []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0000447
name: obsolete increased myosin protein level
def: "OBSOLETE. Increase in extent, amount, or degree of myosin protein level." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000448
name: increased pinocytosis
def: "Increase in extent, amount, or degree of pinocytosis." [DDB:pg]
is_a: DDPHENO:0001007 ! aberrant pinocytosis

[Term]
id: DDPHENO:0000449
name: obsolete no synthetic interaction
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0000450
name: decreased number of mounds
def: "Quantitative reduction in mounds." [DDB:pg]
synonym: "decreased number of aggregates" EXACT []
is_a: DDPHENO:0000483 ! aberrant aggregation

[Term]
id: DDPHENO:0000451
name: obsolete increased number of peripheral cells during sexual reproduction
def: "OBSOLETE. Quantitative increase in peripheral cells during sexual reproduction." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000452
name: decreased macrocyst size
def: "Reduction in extent, amount, or degree of macrocysts size." [DDB:pf]
synonym: "small macrocysts" EXACT []
is_a: DDPHENO:0001010 ! aberrant macrocyst formation

[Term]
id: DDPHENO:0000453
name: abolished protein localization to nucleus
alt_id: DDPHENO:0000084
def: "Complete inability to localize a protein to the nucleus." [DDB:pf, DDB:pg]
synonym: "abolished localization to nucleus" BROAD []
synonym: "abolished nuclear protein localization" EXACT []
is_a: DDPHENO:0001336 ! aberrant protein localization to nucleus
is_a: DDPHENO:0001393 ! abolished protein localization

[Term]
id: DDPHENO:0000454
name: decreased cGMP biosynthesis
def: "Reduction in extent, amount, or degree of cGMP biosynthesis." [DDB:pf]
synonym: "decreased accumulation of cGMP" RELATED []
synonym: "decreased cGMP biosynthetic process" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0000455
name: increased cGMP biosynthesis
def: "Increase in extent, amount, or degree of cGMP biosynthesis." [DDB:pf]
synonym: "increased accumulation of cGMP" RELATED []
synonym: "increased cGMP biosynthetic process" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0000456
name: increased actin phosphorylation
def: "Increase in amount or accumulation of actin phosphorylation." [DDB:pf]
is_a: DDPHENO:0000457 ! aberrant actin phosphorylation
is_a: DDPHENO:0001343 ! increased protein phosphorylation

[Term]
id: DDPHENO:0000457
name: aberrant actin phosphorylation
def: "Deviation from the normal, usual, or expected events during actin phosphorylation." [DDB:pg]
is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization
is_a: DDPHENO:0001342 ! aberrant protein phosphorylation

[Term]
id: DDPHENO:0000459
name: increased actin filament polymerization
def: "Increase in extent, amount, or degree of F-actin polymerization." [DDB:pg]
synonym: "increased F-actin polymerization" EXACT []
is_a: DDPHENO:0001445 ! aberrant actin filament polymerization

[Term]
id: DDPHENO:0000461
name: decreased intracellular pH
def: "Reduction of pH in the cell." [DDB:pf]
synonym: "decreased cytosolic pH level" EXACT []
synonym: "intracellular pH reduction" EXACT []
synonym: "reduction of cellular pH" EXACT []
is_a: DDPHENO:0001455 ! aberrant regulation of intracellular pH

[Term]
id: DDPHENO:0000462
name: decreased filopodium formation
def: "Reduction in extent, amount, or degree of filopodium formation." [DDB:pg]
synonym: "decreased filopodium assembly" EXACT []
is_a: DDPHENO:0001028 ! aberrant filopodium formation

[Term]
id: DDPHENO:0000463
name: precocious prespore gene expression
def: "Early onset or faster progression in the expression of prespore genes." [DDB:pf]
synonym: "precocious prespore cell specific gene expression" EXACT []
is_a: DDPHENO:0000370 ! aberrant prespore gene expression
is_a: DDPHENO:0001116 ! precocious gene expression
created_by: pfey
creation_date: 2017-03-23T15:57:06Z

[Term]
id: DDPHENO:0000464
name: aberrant protein localization to contractile vacuole
def: "Deviation from the normal, usual, or expected during localization of a protein to contractile vacuole." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2017-04-20T17:03:31Z

[Term]
id: DDPHENO:0000465
name: obsolete abolished cAMP-induced Ca2+ influx
def: "OBSOLETE. Complete inability for cAMP-induced Ca2+ influx." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0000466
name: abolished positive chemotaxis
def: "Complete inability for chemotaxis." [DDB:pg]
is_a: DDPHENO:0001131 ! abolished taxis
is_a: DDPHENO:0001224 ! aberrant positive chemotaxis

[Term]
id: DDPHENO:0000471
name: aberrant protein localization
def: "Deviation from the normal, usual, or expected localization of a protein." [DDB:pf, DDB:pg]
comment: Use for the altered localization of a protein that is affected by the mutation of another gene product.
is_a: DDPHENO:0001217 ! aberrant cellular localization

[Term]
id: DDPHENO:0000472
name: aberrant regulation of protein modification
def: "Deviation from the normal, usual, or expected events during the regulation of protein modification." [DDB:pg]
synonym: "aberrant regulation of protein modification process" EXACT []
is_a: DDPHENO:0001317 ! aberrant protein modification

[Term]
id: DDPHENO:0000473
name: increased establishment of cell polarity
def: "Increase in extent, amount, or degree of cell polarity establishment." [DDB:pg]
synonym: "increased cell polarity" EXACT []
is_a: DDPHENO:0001029 ! aberrant establishment or maintenance of cell polarity

[Term]
id: DDPHENO:0000474
name: decreased lateral pseudopodium formation
def: "Reduction in extent, amount, or degree of formation of lateral pseudopodia." [DDB:pg]
synonym: "decreased lateral pseudopodium assembly" EXACT []
is_a: DDPHENO:0000477 ! aberrant lateral pseudopodium formation

[Term]
id: DDPHENO:0000475
name: increased resistance to bisphosphonate
def: "Increase in extent, amount, or degree of resistance to the drug bisphosphonate." [DDB:pf]
is_a: DDPHENO:0000040 ! aberrant response to chemical

[Term]
id: DDPHENO:0000477
name: aberrant lateral pseudopodium formation
def: "Deviation from the normal, usual, or expected events during lateral pseudopodium formation." [DDB:pf]
synonym: "aberrant lateral pseudopodium assembly" EXACT []
is_a: DDPHENO:0001027 ! aberrant pseudopodium formation

[Term]
id: DDPHENO:0000478
name: increased lateral pseudopodium formation
def: "Increase in extent, amount, or degree of formation of lateral pseudopods." [DDB:pg]
synonym: "increased lateral pseudopodium assembly" EXACT []
is_a: DDPHENO:0000477 ! aberrant lateral pseudopodium formation

[Term]
id: DDPHENO:0000479
name: obsolete decreased resistance to DNA-damaging agents
def: "OBSOLETE. Decreased tolerance of the normal, usual, or expected events in the presence of DNA damaging agents." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0000480
name: obsolete aberrant cAMP signaling
def: "OBSOLETE. Deviation from the normal, usual, or expected events during cAMP signaling." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000481
name: decreased actin phosphorylation
def: "Reduction in extent, amount, or degree of actin phosphorylation." [DDB:pf]
is_a: DDPHENO:0000457 ! aberrant actin phosphorylation
is_a: DDPHENO:0001344 ! decreased protein phosphorylation

[Term]
id: DDPHENO:0000482
name: aberrant stream morphology
def: "Deviation from the normal, usual, or expected process of streaming." [DDB:pg]
synonym: "aberrant stream development" RELATED []
synonym: "aberrant streaming" EXACT []
is_a: DDPHENO:0000483 ! aberrant aggregation

[Term]
id: DDPHENO:0000483
name: aberrant aggregation
alt_id: DDPHENO:0000013
alt_id: DDPHENO:0000539
alt_id: DDPHENO:0000541
def: "Deviation from the normal, usual, or expected events during aggregation." [DDB:pg]
synonym: "aberrant aggregation involved in sorocarp development" EXACT []
synonym: "merged_aberrant formation of the aggregation territory" RELATED []
synonym: "merged_aggregation defective" EXACT []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0000484
name: obsolete curly fingers
def: "OBSOLETE. Eas not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0000486
name: increased resistance to spectinomycin
def: "Increase in extent, amount, or degree of resistance to the antibiotic spectinomycin." [DDB:pf]
is_a: DDPHENO:0000040 ! aberrant response to chemical

[Term]
id: DDPHENO:0000487
name: abolished cell migration to prestalk region
def: "Complete inability for cells to migrate to the prestalk region during the slug stage." [DDB:pg]
synonym: "abolished sorting to prestalk region" EXACT []
is_a: DDPHENO:0000306 ! aberrant cell migration to prestalk region

[Term]
id: DDPHENO:0000488
name: delayed response to cAMP
def: "Late onset or slower progression in the response to cAMP." [DDB:pg]
is_a: DDPHENO:0000358 ! aberrant response to cAMP

[Term]
id: DDPHENO:0000489
name: obsolete increased cytosolic Ca2+ response
def: "OBSOLETE. Increase in extent, amount, or degree of cytosolic Ca2+ response." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0000490
name: decreased calcium ion import
def: "Reduction in extent, amount, or degree of uptake of extracellular calcium." [DDB:pg]
synonym: "decreased extracellular Ca2+ uptake" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0000491
name: abolished defense response to bacterium
def: "Complete inability for a defense response to a bacterium." [DDB:pf]
is_a: DDPHENO:0000258 ! aberrant defense response to bacterium

[Term]
id: DDPHENO:0000492
name: abolished stream development
def: "Complete inability for streaming during early development." [DDB:pf]
synonym: "abolished development of streams" EXACT []
synonym: "abolished streaming" EXACT []
is_a: DDPHENO:0000482 ! aberrant stream morphology

[Term]
id: DDPHENO:0000493
name: obsolete abolished CRAC localization to the plasma membrane
def: "OBSOLETE. Complete inability for CRAC localization to the plasma membrane." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000494
name: obsolete aberrant adaptation of adenylate cyclase
def: "OBSOLETE. Deviation from the normal, usual, or expected events during the adaptation of adenylate cyclase." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000495
name: decreased DNA methylation on cytosine
def: "Reduction in extent, amount, or degree of cytosine methylation in genomic DNA." [DDB:pg]
is_a: DDPHENO:0001247 ! aberrant protein methylation

[Term]
id: DDPHENO:0000497
name: decreased number of vacuoles
def: "Quantitative reduction in vacuoles." [DDB:pg]
is_a: DDPHENO:0001041 ! aberrant vacuole organization

[Term]
id: DDPHENO:0000498
name: abolished autophagosome organization
def: "Complete inability to form autophagic vacuoles." [DDB:pg]
synonym: "abolished autophagic vacuole formation" EXACT []
is_a: DDPHENO:0000684 ! abolished vacuole organization
is_a: DDPHENO:0001041 ! aberrant vacuole organization

[Term]
id: DDPHENO:0000499
name: abolished cell-substrate adhesion
def: "Complete inability for cell-substrate adhesion." [DDB:pg]
synonym: "abolished substrate adhesion" RELATED []
is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion

[Term]
id: DDPHENO:0000500
name: decreased pinosome size
def: "Decreased size of pinosomes." [DDB:pf]
is_a: DDPHENO:0001007 ! aberrant pinocytosis

[Term]
id: DDPHENO:0000501
name: increased number of pinosomes
def: "Quantitative increase in pinosomes." [DDB:pg]
is_a: DDPHENO:0001007 ! aberrant pinocytosis

[Term]
id: DDPHENO:0000503
name: precocious culmination
def: "Early onset or faster progression through culmination." [DDB:pg]
synonym: "precocious culmination involved in sorocarp development" EXACT []
is_a: DDPHENO:0001015 ! aberrant culmination

[Term]
id: DDPHENO:0000504
name: decreased sporulation
alt_id: DDPHENO:0000194
def: "Reduction in extent, amount, or degree of spore formation." [DDB:pf]
synonym: "decreased number of spores" RELATED []
is_a: DDPHENO:0000513 ! aberrant sporulation

[Term]
id: DDPHENO:0000509
name: obsolete delayed development in the presence of TMB-8
def: "OBSOLETE. Late onset or slower progression for development in the oresence of TMB-8." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0000510
name: aberrant stalk morphogenesis
def: "Deviation from the normal, usual, or expected events during stalk morphogenesis." [DDB:pg]
is_a: DDPHENO:0000009 ! aberrant fruiting body morphology
is_a: DDPHENO:0001015 ! aberrant culmination

[Term]
id: DDPHENO:0000512
name: abolished prestalk cell differentiation
def: "Complete inability for differentiation of prestalk cells." [DDB:pg]
synonym: "abolished pst cell differentiation" EXACT []
is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation
is_a: DDPHENO:0001176 ! abolished cell differentiation

[Term]
id: DDPHENO:0000513
name: aberrant sporulation
alt_id: DDPHENO:0000023
def: "Deviation from the normal, usual, or expected events during spore formation." [DDB:pf]
synonym: "aberrant spore differentiation" RELATED []
synonym: "defective spore differentiation" RELATED []
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0000514
name: abolished stalk cell differentiation
def: "Complete inability for differentiation into stalk cells." [DDB:pg]
is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation
is_a: DDPHENO:0001176 ! abolished cell differentiation

[Term]
id: DDPHENO:0000516
name: abolished prespore cell differentiation
def: "Complete inability for differentiation of prespore cells." [DDB:pg]
is_a: DDPHENO:0001025 ! aberrant prespore cell differentiation
is_a: DDPHENO:0001176 ! abolished cell differentiation

[Term]
id: DDPHENO:0000517
name: abolished protein localization to contractile vacuole
def: "Complete inability to localize a protein to the contractile vacuole." [DDB:pf]
is_a: DDPHENO:0000464 ! aberrant protein localization to contractile vacuole
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2017-04-20T17:07:45Z

[Term]
id: DDPHENO:0000518
name: increased stalk width
def: "Having a relative thick stalk." [DDB:pg]
synonym: "thick stalk" EXACT []
xref: PATO:0000599
is_a: DDPHENO:0000510 ! aberrant stalk morphogenesis

[Term]
id: DDPHENO:0000519
name: aberrant protein localization to contractile vacuole membrane
def: "Deviation from the normal, usual, or expected during localization of a protein to the contractile vacuole membrane." [DDB:pf]
synonym: "aberrant protein localization to contractile vacuolar membrane" EXACT []
is_a: DDPHENO:0000464 ! aberrant protein localization to contractile vacuole
created_by: pfey
creation_date: 2017-04-20T17:11:27Z

[Term]
id: DDPHENO:0000520
name: obsolete abolished stalk cell differentiation in vitro
def: "OBSOLETE. Complete inability for differentiation into stalk cells in vitro." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000521
name: abolished protein localization to contractile vacuole membrane
def: "Complete inability to localize a protein to the contractile vacuole membrane." [DDB:pf]
synonym: "abolished localization to contractile vacuolar membrane" EXACT []
is_a: DDPHENO:0000517 ! abolished protein localization to contractile vacuole
is_a: DDPHENO:0000519 ! aberrant protein localization to contractile vacuole membrane
created_by: pfey
creation_date: 2017-04-20T17:14:01Z

[Term]
id: DDPHENO:0000522
name: decreased chemotaxis to cAMP
def: "Reduction in extent, amount, or degree of chemotaxis in response to cAMP." [DDB:pg]
synonym: "" RELATED []
synonym: "decreased positive chemotaxis to cAMP" EXACT []
is_a: DDPHENO:0000099 ! decreased chemotaxis rate
is_a: DDPHENO:0001167 ! aberrant chemotaxis to cAMP

[Term]
id: DDPHENO:0000523
name: decreased chemotaxis to folate
def: "Reduction in extent, amount, or degree of chemotaxis in response to folate." [DDB:pg]
synonym: "decreased chemotaxis to folic acid" EXACT []
synonym: "decreased positive chemotaxis to folate" EXACT []
synonym: "decreased positive chemotaxis to folic acid" EXACT []
is_a: DDPHENO:0000099 ! decreased chemotaxis rate
is_a: DDPHENO:0001168 ! aberrant chemotaxis to folate

[Term]
id: DDPHENO:0000524
name: increased cell migration to prestalk region
def: "Increase in extent, amount, or degree of cell migration to the prestalk region during the slug stage." [DDB:pg]
synonym: "increased sorting to prestalk region" EXACT []
is_a: DDPHENO:0000306 ! aberrant cell migration to prestalk region

[Term]
id: DDPHENO:0000525
name: delayed cell cycle
def: "Increase in relative or proportionate duration of the cell cycle." [DDB:pf]
synonym: "increased cell cycle duration" EXACT []
is_a: DDPHENO:0001418 ! aberrant cell cycle

[Term]
id: DDPHENO:0000526
name: obsolete increased prestalk cell differentiation in response to DIF-1
def: "OBSOLETE Increase in extent, amount, or degree of prestalk differentiation factor." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0000527
name: abolished histone H3-K4 methylation
def: "Complete inability for methylation of histone H3 at lysine 4." [DDB:pg]
is_a: DDPHENO:0001476 ! abolished histone lysine methylation

[Term]
id: DDPHENO:0000528
name: increased rate of endocytosis
def: "Increase in extent, amount, or degree of endocytosis." [DDB:pf]
is_a: DDPHENO:0000090 ! aberrant endocytosis

[Term]
id: DDPHENO:0000529
name: increased stalk cell differentiation
def: "Increase in extent, amount, or degree of differentiation into stalk cells." [DDB:pgg]
synonym: "increased number of stalk cells" RELATED []
is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation
is_a: DDPHENO:0001174 ! increased cell differentiation

[Term]
id: DDPHENO:0000530
name: increased post-transciptional gene silencing by RNA
def: "Increase in extent, amount, or degree of post-transciptional gene silencing by RNA." [DDB:pf]
is_a: DDPHENO:0000008 ! aberrant post-transciptional gene silencing by RNA

[Term]
id: DDPHENO:0000531
name: increased contractile vacuole size
def: "Increase in relative or proportionate dimensions of the contractile vacuole." [DDB:pf]
is_a: DDPHENO:0001066 ! aberrant contractile vacuole morphology
created_by: pfey
creation_date: 2017-04-20T17:56:20Z

[Term]
id: DDPHENO:0000532
name: increased number of contractile vacuoles
def: "Quantitative increase in contractile vacuoles." [DDB:pf]
is_a: DDPHENO:0000233 ! aberrant contractile vacuole organization
created_by: pfey
creation_date: 2017-04-20T18:02:17Z

[Term]
id: DDPHENO:0000533
name: aberrant mitotic anaphase
def: "Deviation from the normal, usual, or expected events during mitotic anaphase." [DDB:pf]
is_a: DDPHENO:0000234 ! aberrant mitosis

[Term]
id: DDPHENO:0000535
name: decreased glycogen level
def: "Reduction in amount or accumulation of intracellular glycogen." [DDB:pg]
synonym: "decreased cytosolic glycogen level" EXACT []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0000536
name: increased glutamate level
def: "Increase in amount or accumulation of intracellular glutamate." [DDB:pg]
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0000537
name: increased ammonia level
alt_id: DDPHENO:0001380
def: "Increase in amount or accumulation of ammonia." [DDB:pf]
synonym: "increased extracellular ammonia level" NARROW []
synonym: "increased intracellular ammonia level" NARROW []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0000538
name: decreased pteridine level
def: "Reduction in amount or accumulation of intracellular pteridine." [DDB:pg]
synonym: "decreased cytosolic pteridine level" EXACT []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0000540
name: increased pseudopodium size
def: "Increase in relative or proportionate dimensions of the pseudopodium." [DDB:pg]
is_a: DDPHENO:0001027 ! aberrant pseudopodium formation

[Term]
id: DDPHENO:0000542
name: obsolete increased infection rate by Legionella pneumophila
def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0000543
name: obsolete increased infection rate by Mycobacterium avium
def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf]
synonym: "increased sensitivity to infection by Mycobacterium avium" RELATED []
is_obsolete: true

[Term]
id: DDPHENO:0000544
name: abolished iron ion transport
def: "Complete inability to transport iron." [DDB:pg]
is_a: DDPHENO:0001026 ! aberrant ion transport

[Term]
id: DDPHENO:0000545
name: increased iron ion transport
def: "Increase in extent, amount, or degree of transport of iron." [DDB:pg]
is_a: DDPHENO:0001026 ! aberrant ion transport

[Term]
id: DDPHENO:0000546
name: aberrant stalk cell differentiation
def: "Deviation from the normal, usual, or expected events during differentiation of stalk cells." [DDB:pg]
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0000547
name: aberrant late culminant morphology
def: "Deviation from the normal, usual, or expected morphology of the late culminant." [DDB:pf]
is_a: DDPHENO:0001015 ! aberrant culmination

[Term]
id: DDPHENO:0000549
name: decreased stalk width
def: "Having a relative thin stalk." [DDB:pg]
synonym: "thin stalk" EXACT []
xref: PATO:0000600
is_a: DDPHENO:0000510 ! aberrant stalk morphogenesis

[Term]
id: DDPHENO:0000550
name: abolished pinocytosis
def: "Complete inability to perform phagocytosis." [DDB:pg]
is_a: DDPHENO:0001007 ! aberrant pinocytosis

[Term]
id: DDPHENO:0000551
name: increased pseudopodium formation
def: "Increase in extent, amount, or degree of formation of pseudopodia." [DDB:pg]
synonym: "increased pseudopod extension" RELATED []
synonym: "increased pseudopodium assembly" EXACT []
is_a: DDPHENO:0001027 ! aberrant pseudopodium formation

[Term]
id: DDPHENO:0000552
name: abolished contractile vacuole organization
def: "Complete inability to form a functional contractile vacuole." [DDB:pf]
synonym: "abolished contractile vacuole formation" EXACT []
is_a: DDPHENO:0000233 ! aberrant contractile vacuole organization
is_a: DDPHENO:0000684 ! abolished vacuole organization
created_by: pfey
creation_date: 2017-04-20T18:05:43Z

[Term]
id: DDPHENO:0000553
name: aberrant establishment of contractile vacuole localization
def: "Deviation from the normal, usual, or expected establishment of contractile vacuole localization." [DDB:pf]
synonym: "aberrant contractile vacuole localization" RELATED []
is_a: DDPHENO:0001218 ! aberrant organelle localization
created_by: pfey
creation_date: 2017-04-20T18:12:09Z

[Term]
id: DDPHENO:0000554
name: aberrant contractile vacuole tethering involved in discharge
def: "Deviation from the normal, usual, or expected events during contractile vacuole attachment to the plasma membrane involved in discharge." [DDB:pf]
synonym: "aberrant contractile vacuole tethering to plasma membrane" NARROW []
is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge
created_by: pfey
creation_date: 2017-05-04T10:54:14Z

[Term]
id: DDPHENO:0000555
name: abolished contractile vacuole tethering involved in discharge
def: "Complete inability for contractile vacuole tethering involved in discharge." [DDB:pf]
synonym: "abolished contractile vacuole tethering to plasma membrane" RELATED []
is_a: DDPHENO:0000554 ! aberrant contractile vacuole tethering involved in discharge
created_by: pfey
creation_date: 2017-05-04T12:28:53Z

[Term]
id: DDPHENO:0000556
name: aberrant contractile vacuole dissociation from plasma membrane
def: "Deviation from the normal, usual, or expected events during contractile vacuole dissociation from plasma membrane after discharge." [DDB:pf]
synonym: "aberrant contractile vacuole detethering from plasma membrane" RELATED []
is_a: DDPHENO:0001047 ! aberrant transport
created_by: pfey
creation_date: 2017-05-04T12:44:12Z

[Term]
id: DDPHENO:0000557
name: abolished contractile vacuole dissociation from plasma membrane
def: "Complete inability of contractile vacuole dissociation from plasma membrane after discharge." [DDB:pf]
synonym: "abolished contractile vacuole detethering from plasma membrane" RELATED []
is_a: DDPHENO:0000556 ! aberrant contractile vacuole dissociation from plasma membrane
created_by: pfey
creation_date: 2017-05-04T12:44:52Z

[Term]
id: DDPHENO:0000558
name: aberrant pore formation during contractile vacuole discharge
def: "Deviation from the normal, usual, or expected events during pore formation, part of contractile vacuole discharge." [DDB:pf]
is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge
created_by: pfey
creation_date: 2017-05-16T16:22:59Z

[Term]
id: DDPHENO:0000559
name: abolished pore formation during contractile vacuole discharge
def: "Complete inability for pore formation, part of contractile vacuole discharge." [DDB:pf]
is_a: DDPHENO:0000558 ! aberrant pore formation during contractile vacuole discharge
created_by: pfey
creation_date: 2017-05-16T16:23:33Z

[Term]
id: DDPHENO:0000560
name: aberrant endosomal vesicle fusion
def: "Deviation from the normal, usual, or expected events during homotypic fusion of endocytic vesicles to form or add to an early endosome." [DDB:pf]
synonym: "aberrant endosome fusion" EXACT []
synonym: "aberrant phagocytic vesicle fusion" NARROW []
synonym: "aberrant phagosome fusion" NARROW []
is_a: DDPHENO:0000090 ! aberrant endocytosis
created_by: pfey
creation_date: 2017-06-12T17:03:48Z

[Term]
id: DDPHENO:0000561
name: decreased endosomal vesicle fusion
def: "Reduction in extent, amount, or degree of homotypic fusion of endocytic vesicles to form or add to an early endosome." [DDB:pf]
synonym: "decreased endosome fusion" EXACT []
synonym: "decreased phagocytic vesicle fusion" NARROW []
synonym: "decreased phagosome fusion" NARROW []
is_a: DDPHENO:0000560 ! aberrant endosomal vesicle fusion
created_by: pfey
creation_date: 2017-06-12T17:04:12Z

[Term]
id: DDPHENO:0000562
name: increased endosomal vesicle fusion
def: "Increase in extent, amount, or degree of homotypic fusion of endocytic vesicles to form or add to an early endosome." [DDB:pf]
synonym: "increased endosome fusion" EXACT []
synonym: "increased phagocytic vesicle fusion" NARROW []
synonym: "increased phagosome fusion" NARROW []
is_a: DDPHENO:0000560 ! aberrant endosomal vesicle fusion
created_by: pfey
creation_date: 2017-06-12T17:04:27Z

[Term]
id: DDPHENO:0000563
name: aberrant endoplasmic reticulum organization
def: "Deviation from the normal, usual, or expected events during endoplasmic reticulum organization." [DDB:pf]
synonym: "aberrant ER organization" EXACT []
is_a: DDPHENO:0001043 ! aberrant organelle organization
created_by: pfey
creation_date: 2017-08-10T12:20:08Z

[Term]
id: DDPHENO:0000564
name: aberrant endoplasmic reticulum membrane organization
def: "Deviation from the normal, usual, or expected events during endoplasmic reticulum membrane organization." [DDB:pf]
synonym: "aberrant ER membrane organization" EXACT []
is_a: DDPHENO:0000563 ! aberrant endoplasmic reticulum organization
created_by: pfey
creation_date: 2017-08-10T12:22:33Z

[Term]
id: DDPHENO:0000565
name: obsolete increased endoplasmic reticulum membrane accumulation
def: "OBSOLETE. Quantitative increase in endoplasmic reticulum membrane accumulation." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2017-08-10T12:24:55Z

[Term]
id: DDPHENO:0000566
name: aberrant lipid storage
def: "Deviation from the normal, usual, or expected storage of lipids." [DDB:pf]
is_a: DDPHENO:0001217 ! aberrant cellular localization
created_by: pfey
creation_date: 2017-10-24T11:44:39Z

[Term]
id: DDPHENO:0000567
name: aberrant lipid droplet formation
def: "Deviation from the normal, usual, or expected formation of lipid droplets." [DDB:pf]
is_a: DDPHENO:0000566 ! aberrant lipid storage
created_by: pfey
creation_date: 2017-10-24T11:46:08Z

[Term]
id: DDPHENO:0000568
name: decreased lipid droplet formation
def: "Reduction in amount or accumulation of lipid droplets." [DDB:pf]
is_a: DDPHENO:0000567 ! aberrant lipid droplet formation
created_by: pfey
creation_date: 2017-10-24T11:48:06Z

[Term]
id: DDPHENO:0000569
name: increased lipid droplet formation
def: "Increase in amount or accumulation of lipid droplets." [DDB:pf]
is_a: DDPHENO:0000567 ! aberrant lipid droplet formation
created_by: pfey
creation_date: 2017-10-24T11:50:05Z

[Term]
id: DDPHENO:0000570
name: abolished lipid droplet formation
def: "Complete inability to form lipid droplets." [DDB:pf]
is_a: DDPHENO:0000567 ! aberrant lipid droplet formation
created_by: pfey
creation_date: 2017-10-24T11:51:58Z

[Term]
id: DDPHENO:0000571
name: aberrant double-strand break repair via homologous recombination
def: "Deviation from the normal, usual, or expected events during double-strand break repair of DNA via homologous recombination." [DDB:pf]
synonym: "aberrant double-strand break repair via HR" EXACT []
synonym: "aberrant DSB repair via homologous recombination" EXACT []
is_a: DDPHENO:0000244 ! aberrant double-strand break repair
created_by: pfey
creation_date: 2017-11-30T15:45:59Z

[Term]
id: DDPHENO:0000572
name: decreased double-strand break repair via homologous recombination
def: "Reduction in extent, amount, or degree of double strand break repair of DNA via homologous recombination." [DDB:pf]
synonym: "decreased double-strand break repair via HR" EXACT []
synonym: "decreased DSB repair via homologous recombination" EXACT []
is_a: DDPHENO:0000245 ! decreased double-strand break repair
is_a: DDPHENO:0000571 ! aberrant double-strand break repair via homologous recombination
created_by: pfey
creation_date: 2017-11-30T15:47:40Z

[Term]
id: DDPHENO:0000573
name: abolished double-strand break repair via homologous recombination
def: "Complete inability for double strand break repair of DNA via homologous recombination." [DDB:pf]
synonym: "abolished double-strand break repair via HR" EXACT []
synonym: "abolished DSB repair via homologous recombination" EXACT []
is_a: DDPHENO:0000247 ! abolished double strand break repair
is_a: DDPHENO:0000571 ! aberrant double-strand break repair via homologous recombination
created_by: pfey
creation_date: 2017-11-30T15:52:53Z

[Term]
id: DDPHENO:0000574
name: increased double-strand break repair via homologous recombination
def: "Increased tolerance of the normal, usual, or expected events in double-strand break repair of DNA via homologous recombination." [DDB:pf]
synonym: "increased double-strand break repair via HR" EXACT []
synonym: "increased DSB repair via homologous recombination" EXACT []
is_a: DDPHENO:0000249 ! increased double-strand break repair
is_a: DDPHENO:0000571 ! aberrant double-strand break repair via homologous recombination
created_by: pfey
creation_date: 2017-11-30T15:54:41Z

[Term]
id: DDPHENO:0000575
name: aberrant double-strand break repair via nonhomologous end joining
def: "Deviation from the normal, usual, or expected events during double-strand break repair of DNA via nonhomologous end joining." [DDB:pf]
synonym: "aberrant double-strand break repair via NHEJ" EXACT []
synonym: "aberrant DSB repair via nonhomologous end joining" EXACT []
is_a: DDPHENO:0000244 ! aberrant double-strand break repair
created_by: pfey
creation_date: 2017-11-30T16:25:26Z

[Term]
id: DDPHENO:0000576
name: abolished double-strand break repair via nonhomologous end joining
def: "Complete inability for double strand break repair of DNA via nonhomologous end joining." [DDB:pf]
synonym: "abolished double-strand break repair via NHEJ" EXACT []
synonym: "abolished DSB repair via nonhomologous end joining" EXACT []
is_a: DDPHENO:0000247 ! abolished double strand break repair
is_a: DDPHENO:0000575 ! aberrant double-strand break repair via nonhomologous end joining
created_by: pfey
creation_date: 2017-11-30T16:28:18Z

[Term]
id: DDPHENO:0000577
name: decreased double-strand break repair via nonhomologous end joining
def: "Reduction in extent, amount, or degree of double strand break repair of DNA via nonhomologous end joining." [DDB:pf]
synonym: "decreased double-strand break repair via NHEJ" EXACT []
synonym: "decreased DSB repair via nonhomologous end joining" EXACT []
is_a: DDPHENO:0000245 ! decreased double-strand break repair
is_a: DDPHENO:0000575 ! aberrant double-strand break repair via nonhomologous end joining
created_by: pfey
creation_date: 2017-11-30T16:33:41Z

[Term]
id: DDPHENO:0000578
name: increased double-strand break repair via nonhomologous end joining
def: "Increased tolerance of the normal, usual, or expected events in double-strand break repair of DNA nonhomologous end joining." [DDB:pf]
synonym: "increased double-strand break repair via NHEJ" EXACT []
synonym: "increased DSB repair via nonhomologous end joining" EXACT []
is_a: DDPHENO:0000249 ! increased double-strand break repair
is_a: DDPHENO:0000575 ! aberrant double-strand break repair via nonhomologous end joining
created_by: pfey
creation_date: 2017-11-30T16:34:11Z

[Term]
id: DDPHENO:0000579
name: aberrant cheating during development
def: "Deviation from the normal, usual, or expected sorting to prestalk region when mixed with cheater cells." [DDB:pf]
synonym: "aberrant cheating during chimeric sorocarp development" EXACT []
is_a: DDPHENO:0000127 ! aberrant socially cooperative development
created_by: pfey
creation_date: 2018-01-31T15:28:37Z

[Term]
id: DDPHENO:0000580
name: increased resistance to cheating during development
def: "Increase in extent, amount, or degree of resistance towards cheater cells compared to wild type." [DDB:pf]
synonym: "increased resistance to cheating during chimeric sorocarp development" EXACT []
is_a: DDPHENO:0000579 ! aberrant cheating during development
created_by: pfey
creation_date: 2018-01-31T15:28:50Z

[Term]
id: DDPHENO:0000581
name: decreased resistance to cheating during development
def: "Decreased tolerance of the normal, usual, or expected events towards cheater cells compared to wild type." [DDB:pf]
synonym: "decreased resistance to cheating during chimeric sorocarp development" EXACT []
is_a: DDPHENO:0000579 ! aberrant cheating during development
created_by: pfey
creation_date: 2018-01-31T15:29:25Z

[Term]
id: DDPHENO:0000582
name: obsolete abolished response to cheating
def: "OBSOLETE. Complete resistance to cheating when mixed with cheater cells." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2018-01-31T15:29:40Z

[Term]
id: DDPHENO:0000583
name: aberrant mating type determination
def: "Deviation from the normal, usual, or expected events when determining the mating type of a cell." [DDB:pf]
is_a: DDPHENO:0001443 ! aberrant cell fate determination
created_by: pfey
creation_date: 2019-03-01T15:50:16Z

[Term]
id: DDPHENO:0000584
name: abolished mating type determination
def: "Complete inability for determining the mating type of a cell." [DDB:pf]
is_a: DDPHENO:0000583 ! aberrant mating type determination
created_by: pfey
creation_date: 2019-03-01T15:53:27Z

[Term]
id: DDPHENO:0000585
name: aberrant response to hypoxia
def: "Deviation from the normal, usual, or expected events during the response to hypoxia." [DDB:pf]
synonym: "aberrant response to decreased oxygen" EXACT []
is_a: DDPHENO:0001034 ! aberrant cellular response to stress
created_by: pfey
creation_date: 2019-11-18T14:20:30Z

[Term]
id: DDPHENO:0000586
name: increased resistance to hypoxia
def: "Increased tolerance of the normal, usual, or expected events in the presence of hypoxia." [DDB:pf]
synonym: "increased resistance to decreased oxygen levels" EXACT []
synonym: "increased resistance to detection of hypoxia" EXACT []
is_a: DDPHENO:0000585 ! aberrant response to hypoxia
created_by: pfey
creation_date: 2019-11-18T14:23:53Z

[Term]
id: DDPHENO:0000587
name: decreased resistance to hypoxia
def: "Decreased tolerance of the normal, usual, or expected events in the presence of hypoxia." [DDB:pf]
synonym: "decreased resistance to detection of hypoxia" EXACT []
synonym: "decreased resistance to reduced oxygen levels" EXACT []
is_a: DDPHENO:0000585 ! aberrant response to hypoxia
created_by: pfey
creation_date: 2019-11-18T14:28:11Z

[Term]
id: DDPHENO:0000588
name: decreased response to Gram-positive bacterium
def: "Reduction in extent, amount, or degree of the response to Gram-positive bacterium as a food source." [DDB:pf]
comment: Gram-positive bacteria (examples):\nB. subtilis\nS. aureus\nM. luteus.
synonym: "decreased growth on Gram-positive bacteria" NARROW []
is_a: DDPHENO:0000594 ! decreased response to bacterium
created_by: pfey
creation_date: 2020-04-16T13:44:00Z

[Term]
id: DDPHENO:0000589
name: abolished response to Gram-positive bacterium
def: "Complete inability for cells to respond to Gram-positive bacteria as a food source." [DDB:pf]
comment: Gram-positive bacteria (examples):\nB. subtilis\nS. aureus\nM. luteus.
synonym: "abolished growth on Gram-positive bacteria" NARROW []
is_a: DDPHENO:0000593 ! abolished response to bacterium
created_by: pfey
creation_date: 2020-04-16T13:48:45Z

[Term]
id: DDPHENO:0000590
name: decreased response to Gram-negative bacterium
def: "Reduction in extent, amount, or degree of the response to Gram-negative bacterium as a food source." [DDB:pf]
comment: Gram-negative bacteria (examples):\nK. pneumonia\nE. coli\nP. aeruginosa.
synonym: "decreased growth on Gram-negative bacteria" NARROW []
is_a: DDPHENO:0000594 ! decreased response to bacterium
created_by: pfey
creation_date: 2020-04-16T13:51:28Z

[Term]
id: DDPHENO:0000591
name: abolished response to Gram-negative bacterium
def: "Complete inability for a response to Gram-negative bacteria as a food source." [DDB:pf]
comment: Gram-negative bacteria (examples):\nK. pneumonia\nE. coli\nP. aeruginosa.
synonym: "abolished growth on Gram-negative bacteria" NARROW []
is_a: DDPHENO:0000593 ! abolished response to bacterium
created_by: pfey
creation_date: 2020-04-16T13:53:46Z

[Term]
id: DDPHENO:0000592
name: aberrant response to bacterium
def: "Deviation from the normal, usual, or expected events during the response to bacteria." [DDB:pf]
is_a: DDPHENO:0001226 ! aberrant cellular response to extracellular stimulus
created_by: pfey
creation_date: 2020-05-04T13:08:38Z

[Term]
id: DDPHENO:0000593
name: abolished response to bacterium
def: "Complete inability for a response to bacteria as a food source." [DDB:pf]
is_a: DDPHENO:0000592 ! aberrant response to bacterium
created_by: pfey
creation_date: 2020-05-04T13:12:36Z

[Term]
id: DDPHENO:0000594
name: decreased response to bacterium
def: "Reduction in extent, amount, or degree of the response to bacteria as a food source." [DDB:pf]
is_a: DDPHENO:0000592 ! aberrant response to bacterium
created_by: pfey
creation_date: 2020-05-04T13:13:44Z

[Term]
id: DDPHENO:0000595
name: obsolete increased actin wave formation
def: "OBSOLETE. Increase in extent, amount, or degree of typically cortical actin wave formation." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2020-06-12T09:23:59Z

[Term]
id: DDPHENO:0000596
name: decreased spore stability
def: "Reduction of the time span a spore is viable after sporulation." [DDB:pf]
is_a: DDPHENO:0000513 ! aberrant sporulation
created_by: pfey
creation_date: 2020-06-12T13:55:27Z

[Term]
id: DDPHENO:0000597
name: precocious contractile vacuole discharge
def: "Early onset or faster progression through contractile vacuole discharge." [DDB:pf]
is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge
created_by: pfey
creation_date: 2020-07-06T13:55:30Z

[Term]
id: DDPHENO:0000598
name: decreased number of post-lysosomal vacuoles
def: "Quantitative reduction of the post-lysosomal vacuole number." [DDB:pf]
synonym: "decreased number of postlysosomes" EXACT []
is_a: DDPHENO:0001237 ! aberrant lysosome organization
created_by: pfey
creation_date: 2020-07-07T09:24:23Z

[Term]
id: DDPHENO:0000599
name: decreased post-lysosomal vacuole size
def: "Decrease in relative or proportionate dimensions of the post-lysosomal vacuole." [DDB:pf]
synonym: "decreased postlysosome vacuole size" EXACT []
is_a: DDPHENO:0001237 ! aberrant lysosome organization
created_by: pfey
creation_date: 2020-07-07T09:28:21Z

[Term]
id: DDPHENO:0000600
name: aberrant intermediate filament organization
def: "Deviation from the normal, usual, or expected events during organization of intermediate filaments." [DDB:pf]
is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization
created_by: pfey
creation_date: 2020-08-13T10:08:45Z

[Term]
id: DDPHENO:0000601
name: aberrant intermediate filament bundle assembly
def: "Deviation from the normal, usual, or expected events during intermediate filament bundle assembly." [DDB:pf]
is_a: DDPHENO:0000600 ! aberrant intermediate filament organization
created_by: pfey
creation_date: 2020-08-13T10:10:37Z

[Term]
id: DDPHENO:0000602
name: increased intermediate filament bundle assembly
def: "Quantitative increase in intermediate filament bundle assembly." [DDB:pf]
is_a: DDPHENO:0000601 ! aberrant intermediate filament bundle assembly
created_by: pfey
creation_date: 2020-08-13T10:11:40Z

[Term]
id: DDPHENO:0000603
name: decreased intermediate filament bundle assembly
def: "Reduction in extent, amount, or degree of intermediate filament bundle assembly." [DDB:pf]
is_a: DDPHENO:0000601 ! aberrant intermediate filament bundle assembly
created_by: pfey
creation_date: 2020-08-13T10:17:12Z

[Term]
id: DDPHENO:0000604
name: aberrant protein localization to leading edge
def: "Deviation from the normal, usual, or expected events during localization of a protein to the leading edge." [DDB:pf]
synonym: "aberrant protein localization to cell leading edge" EXACT []
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T12:08:30Z

[Term]
id: DDPHENO:0000605
name: abolished protein localization to leading edge
def: "Complete inability to localize a protein to the leading edge." [DDB:pf]
synonym: "abolished protein localization to cell leading edge" EXACT []
is_a: DDPHENO:0000604 ! aberrant protein localization to leading edge
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T13:00:20Z

[Term]
id: DDPHENO:0000606
name: decreased protein localization to leading edge
def: "Reduction in amount or accumulation of a protein to the leading edge." [DDB:pf]
synonym: "decreased protein localization to cell leading edge" EXACT []
is_a: DDPHENO:0000604 ! aberrant protein localization to leading edge
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T13:02:06Z

[Term]
id: DDPHENO:0000607
name: increased protein localization to leading edge
def: "Increase in amount or accumulation of a protein to the leading edge." [DDB:pf]
synonym: "increased protein localization to cell leading edge" EXACT []
is_a: DDPHENO:0000604 ! aberrant protein localization to leading edge
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T13:08:59Z

[Term]
id: DDPHENO:0000608
name: aberrant protein localization to actin wave
def: "Deviation from the normal, usual, or expected events during localization of a protein to the actin wave." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T13:11:40Z

[Term]
id: DDPHENO:0000609
name: abolished protein localization to actin wave
def: "Complete inability to localize a protein to the actin wave." [DDB:pf]
is_a: DDPHENO:0000608 ! aberrant protein localization to actin wave
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T13:13:07Z

[Term]
id: DDPHENO:0000610
name: decreased protein localization to actin wave
def: "Reduction in amount or accumulation of a protein to the actin wave." [DDB:pf]
is_a: DDPHENO:0000608 ! aberrant protein localization to actin wave
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T13:14:22Z

[Term]
id: DDPHENO:0000611
name: increased protein localization to actin wave
def: "Increase in amount or accumulation of a protein to the actin wave." [DDB:pf]
is_a: DDPHENO:0000608 ! aberrant protein localization to actin wave
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T13:15:31Z

[Term]
id: DDPHENO:0000612
name: aberrant protein localization to trailing edge
def: "Deviation from the normal, usual, or expected events during localization of a protein to the trailing edge." [DDB:pf]
synonym: "aberrant protein localization to cell trailing edge" EXACT []
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T13:16:55Z

[Term]
id: DDPHENO:0000613
name: abolished protein localization to trailing edge
def: "Complete inability to localize a protein to the trailing edge." [DDB:pf]
synonym: "abolished protein localization to cell trailing edge" EXACT []
is_a: DDPHENO:0000612 ! aberrant protein localization to trailing edge
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T13:17:15Z

[Term]
id: DDPHENO:0000614
name: decreased protein localization to trailing edge
def: "Reduction in amount or accumulation of a protein to the trailing edge." [DDB:pf]
synonym: "decreased protein localization to cell trailing edge" EXACT []
is_a: DDPHENO:0000612 ! aberrant protein localization to trailing edge
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T13:17:29Z

[Term]
id: DDPHENO:0000615
name: increased protein localization to trailing edge
def: "Increase in amount or accumulation of a protein to the trailing edge." [DDB:pf]
synonym: "increased protein localization to cell trailing edge" EXACT []
is_a: DDPHENO:0000612 ! aberrant protein localization to trailing edge
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T13:17:43Z

[Term]
id: DDPHENO:0000616
name: aberrant protein localization to filopodium
def: "Deviation from the normal, usual, or expected events during localization of a protein to the filopodia." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T13:24:40Z

[Term]
id: DDPHENO:0000617
name: abolished protein localization to filopodium
def: "Complete inability to localize a protein to the filopodia." [DDB:pf]
is_a: DDPHENO:0000616 ! aberrant protein localization to filopodium
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T13:24:55Z

[Term]
id: DDPHENO:0000618
name: decreased protein localization to filopodium
def: "Reduction in amount or accumulation of a protein to the filopodia." [DDB:pf]
is_a: DDPHENO:0000616 ! aberrant protein localization to filopodium
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T13:25:12Z

[Term]
id: DDPHENO:0000619
name: increased protein localization to filopodium
def: "Increase in amount or accumulation of a protein to the filopodia." [DDB:pf]
is_a: DDPHENO:0000616 ! aberrant protein localization to filopodium
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T13:25:27Z

[Term]
id: DDPHENO:0000620
name: aberrant protein localization to phagocytic vesicle
def: "Deviation from the normal, usual, or expected events during localization of a protein to the phagocytic vesicle." [DDB:pf]
synonym: "aberrant protein localization to phagosome" EXACT []
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T13:34:19Z

[Term]
id: DDPHENO:0000621
name: abolished protein localization to phagocytic vesicle
def: "Complete inability to localize a protein to the phagocytic vesicle." [DDB:pf]
synonym: "abolished protein localization to phagosome" EXACT []
is_a: DDPHENO:0000620 ! aberrant protein localization to phagocytic vesicle
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T13:34:52Z

[Term]
id: DDPHENO:0000622
name: decreased protein localization to phagocytic vesicle
def: "Reduction in amount or accumulation of a protein to the phagocytic vesicle." [DDB:pf]
synonym: "decreased protein localization to phagosome" EXACT []
is_a: DDPHENO:0000620 ! aberrant protein localization to phagocytic vesicle
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T13:36:34Z

[Term]
id: DDPHENO:0000623
name: increased protein localization to phagocytic vesicle
def: "Increase in amount or accumulation of a protein to the phagocytic vesicle." [DDB:pf]
synonym: "increased protein localization to phagosome" EXACT []
is_a: DDPHENO:0000620 ! aberrant protein localization to phagocytic vesicle
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T13:36:52Z

[Term]
id: DDPHENO:0000624
name: aberrant protein localization to centrosome
def: "Deviation from the normal, usual, or expected events during localization of a protein to the centrosome." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T13:48:38Z

[Term]
id: DDPHENO:0000625
name: abolished protein localization to centrosome
def: "Complete inability to localize a protein to the centrosome." [DDB:pf]
is_a: DDPHENO:0000624 ! aberrant protein localization to centrosome
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T13:48:55Z

[Term]
id: DDPHENO:0000626
name: decreased protein localization to centrosome
def: "Reduction in amount or accumulation of a protein to the centrosome." [DDB:pf]
is_a: DDPHENO:0000624 ! aberrant protein localization to centrosome
created_by: pfey
creation_date: 2020-11-05T13:49:09Z

[Term]
id: DDPHENO:0000627
name: increased protein localization to centrosome
def: "Increase in amount or accumulation of a protein to the centrosome." [DDB:pf]
is_a: DDPHENO:0000624 ! aberrant protein localization to centrosome
created_by: pfey
creation_date: 2020-11-05T13:49:27Z

[Term]
id: DDPHENO:0000628
name: aberrant protein localization to macropinosome
def: "Deviation from the normal, usual, or expected events during localization of a protein to the macropinosome." [DDB:pf]
synonym: "aberrant protein localization to macropinocytic cup" EXACT []
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T13:54:49Z

[Term]
id: DDPHENO:0000629
name: abolished protein localization to macropinosome
def: "Complete inability to localize a protein to the macropinosome." [DDB:pf]
synonym: "abolished protein localization to macropinocytic cup" EXACT []
is_a: DDPHENO:0000628 ! aberrant protein localization to macropinosome
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T13:55:37Z

[Term]
id: DDPHENO:0000630
name: decreased protein localization to macropinosome
def: "Reduction in amount or accumulation of a protein to the macropinosome." [DDB:pf]
synonym: "decreased protein localization to macropinocytic cup" EXACT []
is_a: DDPHENO:0000628 ! aberrant protein localization to macropinosome
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T13:55:55Z

[Term]
id: DDPHENO:0000631
name: increased protein localization to macropinosome
def: "Increase in amount or accumulation of a protein to the macropinosome." [DDB:pf]
synonym: "increased protein localization to macropinocytic cup" EXACT []
is_a: DDPHENO:0000628 ! aberrant protein localization to macropinosome
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T13:56:18Z

[Term]
id: DDPHENO:0000632
name: aberrant protein localization to autophagosome
def: "Deviation from the normal, usual, or expected events during localization of a protein to the autophagosome." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T14:18:27Z

[Term]
id: DDPHENO:0000633
name: abolished protein localization to autophagosome
def: "Complete inability to localize a protein to the autophagosome." [DDB:pf]
is_a: DDPHENO:0000632 ! aberrant protein localization to autophagosome
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T14:18:46Z

[Term]
id: DDPHENO:0000634
name: decreased protein localization to autophagosome
def: "Reduction in amount or accumulation of a protein to the autophagosome." [DDB:pf]
is_a: DDPHENO:0000632 ! aberrant protein localization to autophagosome
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T14:19:03Z

[Term]
id: DDPHENO:0000635
name: increased protein localization to autophagosome
def: "Increase in amount or accumulation of a protein to the autophagosome." [DDB:pf]
is_a: DDPHENO:0000632 ! aberrant protein localization to autophagosome
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T14:19:18Z

[Term]
id: DDPHENO:0000636
name: aberrant protein localization to cell-cell contact zone
def: "Deviation from the normal, usual, or expected events during localization of a protein to the cell-cell contact zone." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T14:29:12Z

[Term]
id: DDPHENO:0000637
name: abolished protein localization to cell-cell contact zone
def: "Complete inability to localize a protein to the cell-cell contact zone." [DDB:pf]
is_a: DDPHENO:0000636 ! aberrant protein localization to cell-cell contact zone
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T14:29:33Z

[Term]
id: DDPHENO:0000638
name: decreased protein localization to cell-cell contact zone
def: "Reduction in amount or accumulation of a protein to the cell-cell contact zone." [DDB:pf]
is_a: DDPHENO:0000636 ! aberrant protein localization to cell-cell contact zone
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T14:29:46Z

[Term]
id: DDPHENO:0000639
name: increased protein localization to cell-cell contact zone
def: "Increase in amount or accumulation of a protein to the cell-cell contact zone." [DDB:pf]
is_a: DDPHENO:0000636 ! aberrant protein localization to cell-cell contact zone
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T14:30:03Z

[Term]
id: DDPHENO:0000640
name: aberrant protein localization to basolateral plasma membrane
def: "Deviation from the normal, usual, or expected events during localization of a protein to the basolateral plasma membrane." [DDB:pf]
is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane
created_by: pfey
creation_date: 2020-11-05T16:35:48Z

[Term]
id: DDPHENO:0000641
name: abolished protein localization to basolateral plasma membrane
def: "Complete inability to localize a protein to the basolateral plasma membrane." [DDB:pf]
is_a: DDPHENO:0000640 ! aberrant protein localization to basolateral plasma membrane
is_a: DDPHENO:0001393 ! abolished protein localization
is_a: DDPHENO:0001394 ! abolished protein localization to plasma membrane
created_by: pfey
creation_date: 2020-11-05T16:36:03Z

[Term]
id: DDPHENO:0000642
name: decreased protein localization to basolateral plasma membrane
def: "Reduction in amount or accumulation of a protein to the basolateral plasma membrane." [DDB:pf]
is_a: DDPHENO:0000640 ! aberrant protein localization to basolateral plasma membrane
is_a: DDPHENO:0001395 ! decreased protein localization to plasma membrane
created_by: pfey
creation_date: 2020-11-05T16:36:23Z

[Term]
id: DDPHENO:0000643
name: increased protein localization to basolateral plasma membrane
def: "Increase in amount or accumulation of a protein to the basolateral plasma membrane." [DDB:pf]
is_a: DDPHENO:0000640 ! aberrant protein localization to basolateral plasma membrane
is_a: DDPHENO:0001396 ! increased protein localization to plasma membrane
created_by: pfey
creation_date: 2020-11-05T16:36:44Z

[Term]
id: DDPHENO:0000644
name: aberrant protein localization to cleavage furrow
def: "Deviation from the normal, usual, or expected events during localization of a protein to the cleavage furrow." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T16:40:08Z

[Term]
id: DDPHENO:0000645
name: abolished protein localization to cleavage furrow
def: "Complete inability to localize a protein to the cleavage furrow." [DDB:pf]
is_a: DDPHENO:0000644 ! aberrant protein localization to cleavage furrow
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T16:40:58Z

[Term]
id: DDPHENO:0000646
name: decreased protein localization to cleavage furrow
def: "Reduction in amount or accumulation of a protein to the cleavage furrow." [DDB:pf]
is_a: DDPHENO:0000644 ! aberrant protein localization to cleavage furrow
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T16:41:13Z

[Term]
id: DDPHENO:0000647
name: increased protein localization to cleavage furrow
def: "Increase in amount or accumulation of a protein to the cleavage furrow." [DDB:pf]
is_a: DDPHENO:0000644 ! aberrant protein localization to cleavage furrow
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T16:41:27Z

[Term]
id: DDPHENO:0000648
name: aberrant protein localization to lysosome
def: "Deviation from the normal, usual, or expected events during localization of a protein to the lysosome." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T16:45:10Z

[Term]
id: DDPHENO:0000649
name: abolished protein localization to lysosome
def: "Complete inability to localize a protein to the lysosome." [DDB:pf]
is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T16:45:33Z

[Term]
id: DDPHENO:0000650
name: decreased protein localization to lysosome
def: "Reduction in amount or accumulation of a protein to the lysosome." [DDB:pf]
is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome
created_by: pfey
creation_date: 2020-11-05T16:45:48Z

[Term]
id: DDPHENO:0000651
name: increased protein localization to lysosome
def: "Increase in amount or accumulation of a protein to the lysosome." [DDB:pf]
is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome
created_by: pfey
creation_date: 2020-11-05T16:46:13Z

[Term]
id: DDPHENO:0000652
name: aberrant protein localization to post-lysosomal vacuole
def: "Deviation from the normal, usual, or expected events during localization of a protein to the post-lysosomal vacuole." [DDB:pf]
synonym: "aberrant protein localization to postlysosome" EXACT []
is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome
created_by: pfey
creation_date: 2020-11-05T16:54:22Z

[Term]
id: DDPHENO:0000653
name: abolished protein localization to post-lysosomal vacuole
def: "Complete inability to localize a protein to the post-lysosomal vacuole." [DDB:pf]
synonym: "abolished protein localization to postlysosome" EXACT []
is_a: DDPHENO:0000649 ! abolished protein localization to lysosome
is_a: DDPHENO:0000652 ! aberrant protein localization to post-lysosomal vacuole
created_by: pfey
creation_date: 2020-11-05T16:55:04Z

[Term]
id: DDPHENO:0000654
name: decreased protein localization to post-lysosomal vacuole
def: "Reduction in amount or accumulation of a protein to the post-lysosomal vacuole." [DDB:pf]
synonym: "decreased protein localization to postlysosome" EXACT []
is_a: DDPHENO:0000650 ! decreased protein localization to lysosome
is_a: DDPHENO:0000652 ! aberrant protein localization to post-lysosomal vacuole
created_by: pfey
creation_date: 2020-11-05T16:55:33Z

[Term]
id: DDPHENO:0000655
name: increased protein localization to post-lysosomal vacuole
def: "Increase in amount or accumulation of a protein to the post-lysosomal vacuole." [DDB:pf]
synonym: "increased protein localization to postlysosome" EXACT []
is_a: DDPHENO:0000651 ! increased protein localization to lysosome
is_a: DDPHENO:0000652 ! aberrant protein localization to post-lysosomal vacuole
created_by: pfey
creation_date: 2020-11-05T16:55:46Z

[Term]
id: DDPHENO:0000656
name: aberrant protein localization to lysosomal membrane
def: "Deviation from the normal, usual, or expected events during localization of a protein to the lysosomal membrane." [DDB:pf]
synonym: "aberrant protein localization to lysosome membrane" EXACT []
is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome
created_by: pfey
creation_date: 2020-11-05T17:19:29Z

[Term]
id: DDPHENO:0000657
name: abolished protein localization to lysosomal membrane
def: "Complete inability to localize a protein to the lysosomal membrane." [DDB:pf]
synonym: "abolished protein localization to lysosome membrane" EXACT []
is_a: DDPHENO:0000649 ! abolished protein localization to lysosome
is_a: DDPHENO:0000656 ! aberrant protein localization to lysosomal membrane
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T17:20:08Z

[Term]
id: DDPHENO:0000658
name: decreased protein localization to lysosomal membrane
def: "Reduction in amount or accumulation of a protein to the lysosomal membrane." [DDB:pf]
synonym: "decreased protein localization to lysosome membrane" EXACT []
is_a: DDPHENO:0000650 ! decreased protein localization to lysosome
is_a: DDPHENO:0000656 ! aberrant protein localization to lysosomal membrane
created_by: pfey
creation_date: 2020-11-05T17:20:24Z

[Term]
id: DDPHENO:0000659
name: increased protein localization to lysosomal membrane
def: "Increase in amount or accumulation of a protein to the lysosomal membrane." [DDB:pf]
synonym: "increased protein localization to lysosome membrane" EXACT []
is_a: DDPHENO:0000651 ! increased protein localization to lysosome
is_a: DDPHENO:0000656 ! aberrant protein localization to lysosomal membrane
created_by: pfey
creation_date: 2020-11-05T17:20:37Z

[Term]
id: DDPHENO:0000660
name: aberrant protein localization to mitotic spindle
def: "Deviation from the normal, usual, or expected events during localization of a protein to the mitotic spindle." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T17:27:51Z

[Term]
id: DDPHENO:0000661
name: abolished protein localization to mitotic spindle
def: "Complete inability to localize a protein to the mitotic spindle." [DDB:pf]
is_a: DDPHENO:0000660 ! aberrant protein localization to mitotic spindle
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T17:28:10Z

[Term]
id: DDPHENO:0000662
name: decreased protein localization to mitotic spindle
def: "Reduction in amount or accumulation of a protein to the mitotic spindle." [DDB:pf]
is_a: DDPHENO:0000660 ! aberrant protein localization to mitotic spindle
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T17:28:24Z

[Term]
id: DDPHENO:0000663
name: increased protein localization to mitotic spindle
def: "Increase in amount or accumulation of a protein to the mitotic spindle." [DDB:pf]
is_a: DDPHENO:0000660 ! aberrant protein localization to mitotic spindle
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T17:28:53Z

[Term]
id: DDPHENO:0000664
name: aberrant protein localization to mitotic spindle midzone
def: "Deviation from the normal, usual, or expected events during localization of a protein to the mitotic spindle midzone." [DDB:pf]
is_a: DDPHENO:0000660 ! aberrant protein localization to mitotic spindle
created_by: pfey
creation_date: 2020-11-05T17:29:42Z

[Term]
id: DDPHENO:0000665
name: abolished protein localization to mitotic spindle midzone
def: "Complete inability to localize a protein to the mitotic spindle midzone." [DDB:pf]
is_a: DDPHENO:0000661 ! abolished protein localization to mitotic spindle
is_a: DDPHENO:0000664 ! aberrant protein localization to mitotic spindle midzone
created_by: pfey
creation_date: 2020-11-05T17:30:02Z

[Term]
id: DDPHENO:0000666
name: decreased protein localization to mitotic spindle midzone
def: "Reduction in amount or accumulation of a protein to the mitotic spindle midzone." [DDB:pf]
is_a: DDPHENO:0000662 ! decreased protein localization to mitotic spindle
is_a: DDPHENO:0000664 ! aberrant protein localization to mitotic spindle midzone
created_by: pfey
creation_date: 2020-11-05T17:30:16Z

[Term]
id: DDPHENO:0000667
name: increased protein localization to mitotic spindle midzone
def: "Increase in amount or accumulation of a protein to the mitotic spindle midzone." [DDB:pf]
is_a: DDPHENO:0000663 ! increased protein localization to mitotic spindle
is_a: DDPHENO:0000664 ! aberrant protein localization to mitotic spindle midzone
created_by: pfey
creation_date: 2020-11-05T17:30:31Z

[Term]
id: DDPHENO:0000668
name: aberrant protein localization to cytoplasmic vesicle
def: "Deviation from the normal, usual, or expected events during localization of a protein to the cytoplasmic vesicle." [DDB:pf]
is_a: DDPHENO:0001389 ! aberrant protein localization to cytoplasm
created_by: pfey
creation_date: 2020-11-05T17:43:09Z

[Term]
id: DDPHENO:0000669
name: abolished protein localization to cytoplasmic vesicle
def: "Complete inability to localize a protein to the cytoplasmic vesicle." [DDB:pf]
is_a: DDPHENO:0000668 ! aberrant protein localization to cytoplasmic vesicle
is_a: DDPHENO:0001392 ! abolished protein localization to cytoplasm
created_by: pfey
creation_date: 2020-11-05T17:43:49Z

[Term]
id: DDPHENO:0000670
name: decreased protein localization to cytoplasmic vesicle
def: "Reduction in amount or accumulation of a protein to the cytoplasmic vesicle." [DDB:pf]
is_a: DDPHENO:0000668 ! aberrant protein localization to cytoplasmic vesicle
is_a: DDPHENO:0001391 ! decreased protein localization to cytoplasm
created_by: pfey
creation_date: 2020-11-05T17:45:09Z

[Term]
id: DDPHENO:0000671
name: increased protein localization to cytoplasmic vesicle
def: "Increase in amount or accumulation of a protein to the cytoplasmic vesicle." [DDB:pf]
is_a: DDPHENO:0000668 ! aberrant protein localization to cytoplasmic vesicle
is_a: DDPHENO:0001390 ! increased protein localization to cytoplasm
created_by: pfey
creation_date: 2020-11-05T17:45:22Z

[Term]
id: DDPHENO:0000672
name: aberrant protein localization to cell periphery
def: "Deviation from the normal, usual, or expected events during localization of a protein to the cell periphery." [DDB:pf]
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2020-11-05T17:52:52Z

[Term]
id: DDPHENO:0000673
name: abolished protein localization to cell periphery
def: "Complete inability to localize a protein to the cell periphery." [DDB:pf]
is_a: DDPHENO:0000672 ! aberrant protein localization to cell periphery
is_a: DDPHENO:0001393 ! abolished protein localization
created_by: pfey
creation_date: 2020-11-05T17:54:34Z

[Term]
id: DDPHENO:0000674
name: aberrant protein localization to apical plasma membrane
def: "Deviation from the normal, usual, or expected events during localization of a protein from the cytoplasm to the apical plasma membrane." [DDB:pf]
is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane
created_by: pfey
creation_date: 2020-11-05T18:14:57Z

[Term]
id: DDPHENO:0000675
name: abolished protein localization to apical plasma membrane
def: "Complete inability to localize a protein to the apical plasma membrane." [DDB:pf]
is_a: DDPHENO:0000674 ! aberrant protein localization to apical plasma membrane
is_a: DDPHENO:0001394 ! abolished protein localization to plasma membrane
created_by: pfey
creation_date: 2020-11-05T18:15:44Z

[Term]
id: DDPHENO:0000676
name: aberrant protein localization to endolysosome
def: "Deviation from the normal, usual, or expected events during localization of a protein to the endolysosome." [DDB:pf]
is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome
created_by: pfey
creation_date: 2020-11-05T18:26:02Z

[Term]
id: DDPHENO:0000677
name: abolished protein localization to endolysosome
def: "Complete inability to localize a protein to the endolysosome." [DDB:pf]
is_a: DDPHENO:0000649 ! abolished protein localization to lysosome
is_a: DDPHENO:0000676 ! aberrant protein localization to endolysosome
created_by: pfey
creation_date: 2020-11-05T18:27:17Z

[Term]
id: DDPHENO:0000678
name: decreased protein localization to endolysosome
def: "Reduction in amount or accumulation of a protein to the endolysosome." [DDB:pf]
is_a: DDPHENO:0000650 ! decreased protein localization to lysosome
is_a: DDPHENO:0000676 ! aberrant protein localization to endolysosome
created_by: pfey
creation_date: 2020-11-05T18:27:48Z

[Term]
id: DDPHENO:0000679
name: increased protein localization to endolysosome
def: "Increase in amount or accumulation of a protein to the endolysosome." [DDB:pf]
is_a: DDPHENO:0000651 ! increased protein localization to lysosome
is_a: DDPHENO:0000676 ! aberrant protein localization to endolysosome
created_by: pfey
creation_date: 2020-11-05T18:28:02Z

[Term]
id: DDPHENO:0000680
name: decreased protein localization to contractile vacuole
def: "Reduction in amount or accumulation of a protein to the contractile vacuole." [DDB:pf]
is_a: DDPHENO:0000464 ! aberrant protein localization to contractile vacuole
is_a: DDPHENO:0001338 ! decreased protein localization
created_by: pfey
creation_date: 2020-11-05T20:31:48Z

[Term]
id: DDPHENO:0000681
name: increased protein localization to contractile vacuole
def: "Increase in amount or accumulation of a protein to the contractile vacuole." [DDB:pf]
is_a: DDPHENO:0000464 ! aberrant protein localization to contractile vacuole
is_a: DDPHENO:0001337 ! increased protein localization
created_by: pfey
creation_date: 2020-11-05T20:32:27Z

[Term]
id: DDPHENO:0000682
name: decreased protein localization to contractile vacuole membrane
def: "Reduction in amount or accumulation of a protein to the contractile vacuole membrane." [DDB:pf]
is_a: DDPHENO:0000519 ! aberrant protein localization to contractile vacuole membrane
is_a: DDPHENO:0000680 ! decreased protein localization to contractile vacuole
created_by: pfey
creation_date: 2020-11-05T20:35:24Z

[Term]
id: DDPHENO:0000683
name: increased protein localization to contractile vacuole membrane
def: "Increase in amount or accumulation of a protein to the contractile vacuole membrane." [DDB:pf]
is_a: DDPHENO:0000519 ! aberrant protein localization to contractile vacuole membrane
is_a: DDPHENO:0000681 ! increased protein localization to contractile vacuole
created_by: pfey
creation_date: 2020-11-05T20:36:38Z

[Term]
id: DDPHENO:0000684
name: abolished vacuole organization
def: "Complete inability to form a functional vacuole." [DDB:pf]
synonym: "abolished vacuolar assembly" NARROW []
synonym: "abolished vacuolation" RELATED []
synonym: "abolished vacuole formation" EXACT []
is_a: DDPHENO:0001041 ! aberrant vacuole organization
created_by: pfey
creation_date: 2020-11-24T12:08:23Z

[Term]
id: DDPHENO:0000685
name: development arrests at standing slug stage
def: "Development cannot progress past the standing slug stage." [DDB:pf]
synonym: "development arrests at finger stage" EXACT []
is_a: DDPHENO:0000154 ! aberrant sorocarp development
created_by: pfey
creation_date: 2021-02-01T17:24:09Z

[Term]
id: DDPHENO:0000686
name: development arrests at early culminant stage
def: "Development cannot progress past the early culminant stage." [DDB:pf]
synonym: "development arrests at mexican hat stage" BROAD []
is_a: DDPHENO:0000154 ! aberrant sorocarp development
created_by: pfey
creation_date: 2021-02-01T17:26:52Z

[Term]
id: DDPHENO:0000687
name: development arrests at mid culminant stage
def: "Development cannot progress past the mid culminant stage." [DDB:pf]
synonym: "development arrests at culminant stage" BROAD []
is_a: DDPHENO:0000154 ! aberrant sorocarp development
created_by: pfey
creation_date: 2021-02-01T17:29:26Z

[Term]
id: DDPHENO:0000688
name: development arrests at late culminant stage
def: "Development cannot progress past the late culminant stage." [DDB:pf]
synonym: "development arrests at culminant stage" BROAD []
is_a: DDPHENO:0000154 ! aberrant sorocarp development
created_by: pfey
creation_date: 2021-02-01T17:38:04Z

[Term]
id: DDPHENO:0000689
name: aberrant G protein-coupled receptor signaling
def: "Deviation from the normal, usual, or expected events during G protein-coupled signaling." [DDB:pf]
synonym: "aberrant G protein-coupled receptor signaling pathway" EXACT []
synonym: "aberrant GPCR signaling" EXACT []
is_a: DDPHENO:0001118 ! aberrant signal transduction
created_by: pfey
creation_date: 2021-04-28T10:46:00Z

[Term]
id: DDPHENO:0000690
name: aberrant spore cell differentiation
def: "Deviation from the normal, usual, or expected events during differentiation into spores during culmination." [DDB:pf]
synonym: "aberrant sorocarp spore cell differentiation" EXACT []
is_a: DDPHENO:0001013 ! aberrant cell differentiation
created_by: pfey
creation_date: 2021-04-28T18:08:10Z

[Term]
id: DDPHENO:0000691
name: abolished spore cell differentiation
def: "Complete inability for differentiation of spore cells during culmination." [DDB:pf]
synonym: "abolished sorocarp spore cell differentiation" EXACT []
is_a: DDPHENO:0000690 ! aberrant spore cell differentiation
created_by: pfey
creation_date: 2021-04-28T18:11:09Z

[Term]
id: DDPHENO:0000692
name: decreased spore cell differentiation
def: "Reduction in extent, amount, or degree of differentiation into spore cells during culmination." [DDB:pf]
synonym: "decreased sorocarp spore cell differentiation" EXACT []
is_a: DDPHENO:0000690 ! aberrant spore cell differentiation
created_by: pfey
creation_date: 2021-04-28T18:12:42Z

[Term]
id: DDPHENO:0000693
name: abolished response to biotic stimulus
def: "Complete inability for response to a biotic stimulus." [DDB:pf]
is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus
created_by: pfey
creation_date: 2021-04-28T18:19:37Z

[Term]
id: DDPHENO:0000694
name: aberrant cGMP-mediated signaling
def: "Deviation from the normal, usual, or expected events during cGMP-mediated signaling." [DDB:pf]
synonym: "aberrant cyclic GMP-mediated signaling" EXACT []
is_a: DDPHENO:0001118 ! aberrant signal transduction
created_by: pfey
creation_date: 2021-04-29T11:28:03Z

[Term]
id: DDPHENO:0000695
name: aberrant cAMP level
def: "Deviation from the normal, usual, or expected cAMP level." [DDB:pf]
is_a: DDPHENO:0001118 ! aberrant signal transduction
created_by: pfey
creation_date: 2021-04-29T18:22:43Z

[Term]
id: DDPHENO:0000696
name: decreased cAMP level
def: "Reduction in extent, amount, or degree of the cAMP level." [DDB:pf]
is_a: DDPHENO:0000695 ! aberrant cAMP level
created_by: pfey
creation_date: 2021-04-29T18:25:17Z

[Term]
id: DDPHENO:0000697
name: increased cAMP level
def: "Increase in extent, amount, or degree of cAMP level." [DDB:pf]
is_a: DDPHENO:0000695 ! aberrant cAMP level
created_by: pfey
creation_date: 2021-04-29T18:26:58Z

[Term]
id: DDPHENO:0000698
name: aberrant epithelium-like organization
def: "Deviation from the normal, usual, or expected events during epithelium-like organization." [DDB:pf]
is_a: DDPHENO:0001015 ! aberrant culmination
created_by: pfey
creation_date: 2021-06-11T10:16:34Z

[Term]
id: DDPHENO:0000699
name: decreased epithelium-like organization
def: "Reduction in extent, amount, or degree of epithelium-like organization." [DDB:pf]
is_a: DDPHENO:0000698 ! aberrant epithelium-like organization
created_by: pfey
creation_date: 2021-06-11T10:17:55Z

[Term]
id: DDPHENO:0000700
name: abolished epithelium-like organization
def: "Complete inability for epithelium-like organization." [DDB:pf]
is_a: DDPHENO:0000698 ! aberrant epithelium-like organization
created_by: pfey
creation_date: 2021-06-11T10:19:25Z

[Term]
id: DDPHENO:0000701
name: aberrant aggregation territory size
def: "Deviation from the normal, usual, or expected events during the development of the aggregation territory size." [DDB:pf]
xref: PMID:18366659 "DDANAT:0000003"
is_a: DDPHENO:0000483 ! aberrant aggregation
created_by: pfey
creation_date: 2021-06-14T17:50:44Z

[Term]
id: DDPHENO:0000702
name: decreased aggregation territory size
def: "Reduction in relative or proportionate dimensions of the aggregation territory." [DDB:pf]
is_a: DDPHENO:0000701 ! aberrant aggregation territory size
created_by: pfey
creation_date: 2021-06-14T17:52:35Z

[Term]
id: DDPHENO:0000703
name: increased aggregation territory size
def: "Increase in relative or proportionate dimensions of the aggregation territory." [DDB:pf]
is_a: DDPHENO:0000701 ! aberrant aggregation territory size
created_by: pfey
creation_date: 2021-06-14T17:54:12Z

[Term]
id: DDPHENO:0000704
name: abolished cAMP biosynthesis
def: "Complete inability for cAMP biosynthesis." [DDB:pf]
synonym: "abolished cAMP biosynthetic process" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2021-06-15T15:51:38Z

[Term]
id: DDPHENO:0000705
name: decreased cAMP biosynthesis
def: "Reduction in extent, amount, or degree of uptake of cAMP biosynthesis." [DDB:pf]
synonym: "decreased cAMP biosynthetic process" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2021-06-15T15:55:09Z

[Term]
id: DDPHENO:0000706
name: increased cAMP biosynthesis
def: "Increase in extent, amount, or degree of cAMP biosynthesis." [DDB:pf]
synonym: "increased cAMP biosynthetic process" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2021-06-15T15:56:51Z

[Term]
id: DDPHENO:0000707
name: obsolete aberrant response to phleomycin
def: "OBSOLETE. Deviation from the normal, usual, or expected during the response to phleomycin." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2021-06-21T15:50:58Z

[Term]
id: DDPHENO:0000708
name: decreased resistance to phleomycin
def: "Decreased tolerance of the normal, usual, or expected events in the presence of phleomycin." [DDB:pf]
is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus
created_by: pfey
creation_date: 2021-06-21T15:52:31Z

[Term]
id: DDPHENO:0000709
name: increased resistance to phleomycin
def: "Increased tolerance of the normal, usual, or expected events in the presence of phleomycin." [DDB:pf]
is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus
created_by: pfey
creation_date: 2021-06-21T15:53:45Z

[Term]
id: DDPHENO:0000710
name: aberrant response to bleomycin
def: "Deviation from the normal, usual, or expected during the response to bleomycin." [DDB:pf]
is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus
created_by: pfey
creation_date: 2021-06-21T16:01:45Z

[Term]
id: DDPHENO:0000711
name: decreased resistance to bleomycin
def: "Decreased tolerance of the normal, usual, or expected events in the presence of bleomycin." [DDB:pf]
is_a: DDPHENO:0000710 ! aberrant response to bleomycin
created_by: pfey
creation_date: 2021-06-21T16:38:38Z

[Term]
id: DDPHENO:0000712
name: increased resistance to bleomycin
def: "Increased tolerance of the normal, usual, or expected events in the presence of bleomycin." [DDB:pf]
is_a: DDPHENO:0000710 ! aberrant response to bleomycin
created_by: pfey
creation_date: 2021-06-21T16:40:40Z

[Term]
id: DDPHENO:0000713
name: aberrant response to hydroxyurea
def: "Deviation from the normal, usual, or expected events during the response to hydroxyurea." [DDB:pf]
is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus
created_by: pfey
creation_date: 2021-06-21T17:23:28Z

[Term]
id: DDPHENO:0000714
name: increased resistance to hydroxyurea
def: "Increase in extent, amount, or degree of resistance to hydroxyurea." [DDB:pf]
is_a: DDPHENO:0000713 ! aberrant response to hydroxyurea
created_by: pfey
creation_date: 2021-06-21T17:24:34Z

[Term]
id: DDPHENO:0000715
name: decreased resistance to hydroxyurea
def: "Decreased tolerance of the normal, usual, or expected events towards hydroxyurea." [DDB:pf]
is_a: DDPHENO:0000713 ! aberrant response to hydroxyurea
created_by: pfey
creation_date: 2021-06-21T17:25:36Z

[Term]
id: DDPHENO:0000716
name: decreased production of siRNA involved in RNA interference
def: "Reduction in level of modification of siRNA production involved in RNA interference." [DDB:pf]
synonym: "decreased production of siRNA involved in RNAi" EXACT []
is_a: DDPHENO:0000022 ! aberrant production of siRNA involved in RNA interference
created_by: pfey
creation_date: 2021-06-24T12:40:11Z

[Term]
id: DDPHENO:0000717
name: mitotic M phase arrest
def: "The M phase in the mitotic cell cycle cannot complete." [DDB:pf]
synonym: "M phase mitotic cell cycle arrest" EXACT []
is_a: DDPHENO:0001418 ! aberrant cell cycle
created_by: pfey
creation_date: 2021-06-24T14:40:05Z

[Term]
id: DDPHENO:0000718
name: increased post-lysosomal vacuole size
def: "Increase in relative or proportionate dimensions of the post-lysosomal vacuole." [DDB:pf]
synonym: "increased postlysosome size" EXACT []
is_a: DDPHENO:0001237 ! aberrant lysosome organization
created_by: pfey
creation_date: 2021-06-25T09:49:46Z

[Term]
id: DDPHENO:0000719
name: abolished protein tyrosin phosphorylation
def: "Complete inability to phosphorylate a tyrosine residue of a protein." [DDB:pf]
synonym: "abolished peptidyl-tyrosine phosphorylation" EXACT []
is_a: DDPHENO:0001345 ! aberrant protein tyrosine phosphorylation
created_by: pfey
creation_date: 2021-06-25T10:21:47Z

[Term]
id: DDPHENO:0000720
name: increased lateral pseudopodium retraction
def: "Increase in extent, amount, or degree of suppression or retraction of lateral pseudopods." [DDB:pf]
is_a: DDPHENO:0000477 ! aberrant lateral pseudopodium formation
created_by: pfey
creation_date: 2021-06-29T14:28:08Z

[Term]
id: DDPHENO:0000721
name: abolished prestalk gene expression
def: "Complete inability for prestalk expression of genes." [DDB:pf]
synonym: "abolished prestalk cell specific gene expression" EXACT []
is_a: DDPHENO:0000365 ! aberrant prestalk gene expression
is_a: DDPHENO:0001114 ! abolished gene expression
created_by: pfey
creation_date: 2021-08-31T17:39:53Z

[Term]
id: DDPHENO:0000722
name: abolished prespore gene expression
def: "Complete inability for prespore expression of genes." [DDB:pf]
synonym: "abolished prespore cell specific gene expression" EXACT []
is_a: DDPHENO:0000370 ! aberrant prespore gene expression
is_a: DDPHENO:0001114 ! abolished gene expression
created_by: pfey
creation_date: 2021-08-31T17:42:22Z

[Term]
id: DDPHENO:0001001
name: obsolete aberrant initiation of development
def: "OBSOLETE. Deviation from the normal, usual, or expected events duringninitiation of development." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001002
name: aberrant organelle morphology
def: "Deviation from the normal, usual, or expected morphology of organelles." [DDB:pg]
comment: Child of GO:0006996 : organelle organization and biogenesis.
is_a: DDPHENO:0001043 ! aberrant organelle organization

[Term]
id: DDPHENO:0001003
name: aberrant response to stimulus
def: "Deviation from the normal, usual, or expected events during the response to stimulus." [DDB:pg]
comment: Child of GO:0050896 : response to stimulus.
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001004
name: obsolete aberrant cellular physiological process
def: "OBSOLETE. Deviation from the normal, usual, or expected events during cellular physiological process." [DDB:pg]
comment: Obsoleted because GO merged with cellular process. All children moved under DDPHENO:0001008 aberrant cellular process
is_obsolete: true

[Term]
id: DDPHENO:0001005
name: aberrant cellular metabolic process
def: "Deviation from the normal, usual, or expected events during cellular metabolism." [DDB:pg]
comment: Child of GO:0044237: cellular metabolism.
synonym: "aberrant cellular metabolism" EXACT []
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001006
name: aberrant phagocytosis
def: "Deviation from the normal, usual, or expected events during phagocytosis." [DDB:pg]
comment: Child of GO:0006909 : phagocytosis.
is_a: DDPHENO:0000090 ! aberrant endocytosis

[Term]
id: DDPHENO:0001007
name: aberrant pinocytosis
def: "Deviation from the normal, usual, or expected events during pinocytosis." [DDB:pg]
comment: Child of GO:0006907 : pinocytosis.
is_a: DDPHENO:0000090 ! aberrant endocytosis

[Term]
id: DDPHENO:0001008
name: aberrant cellular process
def: "Deviation from the normal, usual, or expected events during cellular processes." [DDB:pg]
comment: Child of GO:0009987 : cellular process.
is_a: DDPHENO:0010000 ! Dicty Phenotypes

[Term]
id: DDPHENO:0001009
name: aberrant localization
def: "Deviation from the normal, usual, or expected events during localization." [DDB:pg]
is_a: DDPHENO:0010000 ! Dicty Phenotypes

[Term]
id: DDPHENO:0001010
name: aberrant macrocyst formation
alt_id: DDPHENO:0000476
def: "Deviation from the normal, usual, or expected events during sexual macrocyst formation." [DDB:pf]
comment: Child of GO:0000747: conjugation with cellular fusion.
synonym: "aberrant aggregation during macrocyst formation" NARROW []
synonym: "aberrant sexual macrocyst formation" EXACT []
synonym: "aberrant sexual reproduction" BROAD []
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0001011
name: obsolete decreased intracellular cAMP level
def: "OBSOLETE. Reduction in extent, amount or degree of intracellular cAMP level." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001012
name: aberrant stalk development
def: "Deviation from the normal, usual, or expected events during stalk development." [DDB:pg]
synonym: "aberrant stalk formation" RELATED []
is_a: DDPHENO:0001015 ! aberrant culmination

[Term]
id: DDPHENO:0001013
name: aberrant cell differentiation
def: "Deviation from the normal, usual, or expected events during cell differentiation." [DDB:pg]
is_a: DDPHENO:0000154 ! aberrant sorocarp development
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001014
name: aberrant slug development
def: "Deviation from the normal, usual, or expected events during slug development." [DDB:pg]
synonym: "aberrant slug development involved in sorocarp development" EXACT []
synonym: "aberrant slug formation" RELATED []
synonym: "pseudoplasmodium development" EXACT []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0001015
name: aberrant culmination
def: "Deviation from the normal, usual, or expected events during culmination." [DDB:pg]
synonym: "aberrant culmination involved in sorocarp development" EXACT []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0001016
name: aberrant regulation of fruiting body formation
def: "Deviation from the normal, usual, or expected events during the regulation of fruiting body formation." [DDB:pg]
synonym: "aberrant regulation of sorocarp formation" EXACT []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0001017
name: aberrant mound size
def: "Deviation from the normal, usual, or expected events during the development of mound size." [DDB:pf]
synonym: "aberrant aggregate size" EXACT []
synonym: "aberrant regulation of aggregation during fruiting body formation" RELATED []
is_a: DDPHENO:0000483 ! aberrant aggregation

[Term]
id: DDPHENO:0001020
name: aberrant regulation of stalk cell differentiation
def: "Deviation from the normal, usual, or expected events during the regulation of stalk cell differentiation." [DDB:pg]
is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation

[Term]
id: DDPHENO:0001021
name: aberrant negative regulation of stalk cell differentiation
def: "Deviation from the normal, usual, or expected events during negative regulation of stalk cell differentiation." [DDB:pg]
is_a: DDPHENO:0001020 ! aberrant regulation of stalk cell differentiation

[Term]
id: DDPHENO:0001022
name: aberrant positive regulation of stalk cell differentiation
def: "Deviation from the normal, usual, or expected events during positive regulation of stalk cell differentiation." [DDB:pg]
is_a: DDPHENO:0001020 ! aberrant regulation of stalk cell differentiation

[Term]
id: DDPHENO:0001023
name: aberrant prestalk cell differentiation
def: "Deviation from the normal, usual, or expected events during differentiation of prestalk cells." [DDB:pg]
synonym: "aberrant pst cell differentiation" EXACT []
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0001024
name: aberrant prestalk O cell differentiation
def: "Deviation from the normal, usual, or expected events during differentiation of prestalk O cells." [DDB:pf]
synonym: "aberrant pstO cell differentiation" EXACT []
is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation

[Term]
id: DDPHENO:0001025
name: aberrant prespore cell differentiation
def: "Deviation from the normal, usual, or expected events during differentiation of prespore cells." [DDB:pg]
synonym: "aberrant psp cell differentiation" EXACT []
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0001026
name: aberrant ion transport
def: "Deviation from the normal, usual, or expected events during ion transport." [DDB:pg]
is_a: DDPHENO:0001047 ! aberrant transport

[Term]
id: DDPHENO:0001027
name: aberrant pseudopodium formation
def: "Deviation from the normal, usual, or expected events during pseudopodium formation." [DDB:pg]
synonym: "aberrant pseudopodium assembly" EXACT []
is_a: DDPHENO:0001048 ! aberrant cell projection biogenesis

[Term]
id: DDPHENO:0001028
name: aberrant filopodium formation
def: "Deviation from the normal, usual, or expected events during filopodium formation." [DDB:pg]
synonym: "aberrant filopodium assembly" EXACT []
is_a: DDPHENO:0001048 ! aberrant cell projection biogenesis

[Term]
id: DDPHENO:0001029
name: aberrant establishment or maintenance of cell polarity
def: "Deviation from the normal, usual, or expected events during establishment and/or maintenance of cell polarity." [DDB:pg]
is_a: DDPHENO:0000236 ! aberrant cell morphology

[Term]
id: DDPHENO:0001030
name: aberrant protein secretion
alt_id: DDPHENO:0000186
def: "Deviation from the normal, usual, or expected events during protein secretion." [DDB:pg]
synonym: "aberrant lysosomal traffic" BROAD []
is_a: DDPHENO:0000471 ! aberrant protein localization
is_a: DDPHENO:0001043 ! aberrant organelle organization

[Term]
id: DDPHENO:0001031
name: aberrant response to abiotic stimulus
def: "Deviation from the normal, usual, or expected events during the response to abiotic stimulus." [DDB:pg]
is_a: DDPHENO:0001003 ! aberrant response to stimulus

[Term]
id: DDPHENO:0001032
name: aberrant response to biotic stimulus
def: "Deviation from the normal, usual, or expected events during the response to biotic stimulus." [DDB:pg]
is_a: DDPHENO:0001003 ! aberrant response to stimulus

[Term]
id: DDPHENO:0001033
name: aberrant macrocyst morphology
def: "Deviation from the normal, usual, or expected morphology of the macrocyst." [DDB:pg]
is_a: DDPHENO:0000236 ! aberrant cell morphology

[Term]
id: DDPHENO:0001034
name: aberrant cellular response to stress
def: "Deviation from the normal, usual, or expected events during the cellular response to stress." [DDB:pf]
is_a: DDPHENO:0001003 ! aberrant response to stimulus

[Term]
id: DDPHENO:0001035
name: aberrant response to heat
def: "Deviation from the normal, usual, or expected events during the response to heat." [DDB:pg]
synonym: "aberrant cellular response to heat" EXACT []
is_a: DDPHENO:0001034 ! aberrant cellular response to stress

[Term]
id: DDPHENO:0001036
name: aberrant response to oxidative stress
def: "Deviation from the normal, usual, or expected events during the response to oxidative stress." [DDB:pg]
is_a: DDPHENO:0001034 ! aberrant cellular response to stress

[Term]
id: DDPHENO:0001037
name: obsolete aberrant signal transduction during aggregation
def: "OBSOLETE. Deviation from the normal, usual, or expected events during signal trnduction during aggregation." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001038
name: aberrant extracellular cAMP signaling
alt_id: DDPHENO:0000419
alt_id: DDPHENO:0000468
alt_id: DDPHENO:0000469
def: "Deviation from the normal, usual, or expected events during extracellular cAMP signaling." [DDB:pf]
comment: Merged with aberrant cAMP signaling during aggregation. PG 10-24-2006.
synonym: "aberrant adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway" EXACT []
synonym: "aberrant cAMP signaling during aggregation" RELATED []
synonym: "aberrant extracellular cAMP signaling pathway" EXACT []
synonym: "merged_aggregation hypersensitive to caffeine" NARROW []
synonym: "merged_aggregation resistant to caffeine" NARROW []
synonym: "merged_impaired cAMP signaling in the presence of gossypol" NARROW []
is_a: DDPHENO:0001118 ! aberrant signal transduction

[Term]
id: DDPHENO:0001039
name: aberrant cellular response to starvation
def: "Deviation from the normal, usual, or expected events during the cellular response to starvation." [DDB:pf]
is_a: DDPHENO:0001034 ! aberrant cellular response to stress

[Term]
id: DDPHENO:0001040
name: obsolete aberrant response to drug
def: "OBSOLETE. Deviation from the normal, usual, or expected events during response to drug." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001041
name: aberrant vacuole organization
def: "Deviation from the normal, usual, or expected process of vacuole organization." [DDB:pf, DDB:pg]
synonym: "aberrant vacuolar assembly" NARROW []
synonym: "aberrant vacuolation" RELATED []
synonym: "aberrant vacuole formation" EXACT []
is_a: DDPHENO:0001043 ! aberrant organelle organization

[Term]
id: DDPHENO:0001042
name: aberrant cellular component organization
def: "Deviation from the normal, usual, or expected events during cellular component organization." [DDB:pf]
synonym: "aberrant cellular component organization or biogenesis" EXACT []
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001043
name: aberrant organelle organization
def: "Deviation from the normal, usual, or expected events during organelle organization." [DDB:pg]
synonym: "aberrant organelle organization and biogenesis" EXACT []
is_a: DDPHENO:0001042 ! aberrant cellular component organization

[Term]
id: DDPHENO:0001044
name: aberrant cell adhesion
def: "Deviation from the normal, usual, or expected events during cell adhesion." [DDB:pg]
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001045
name: obsolete aberrant response to DNA damaging agents
def: "OBSOLETE. Deviation from the normal, usual, or expected events during the response to DNA damaging agents." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001046
name: aberrant spore germination
def: "Deviation from the normal, usual, or expected events during release from spore dormancy." [DDB:pf]
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0001047
name: aberrant transport
def: "Deviation from the normal, usual, or expected events during transport." [DDB:pg]
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001048
name: aberrant cell projection biogenesis
def: "Deviation from the normal, usual, or expected events during cell projection biogenesis." [DDB:pg]
is_a: DDPHENO:0001042 ! aberrant cellular component organization

[Term]
id: DDPHENO:0001049
name: aberrant bleb assembly
def: "Deviation from the normal, usual, or expected events during bleb formation." [DDB:pf]
synonym: "aberrant bleb formation" EXACT []
synonym: "aberrant cell blebbing" RELATED []
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001050
name: abolished bleb assembly
def: "Complete inability to form blebs." [DDB:pf]
synonym: "abolished bleb formation" EXACT []
synonym: "abolished cell blebbing" RELATED []
is_a: DDPHENO:0001049 ! aberrant bleb assembly

[Term]
id: DDPHENO:0001051
name: obsolete abolished chemotaxis during aggregation
def: "OBSOETE. Complete inability for chemotaxis during aggregation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001052
name: decreased bleb assembly
def: "Reduction in extent, amount, or degree of bleb assembly." [DDB:pf]
synonym: "decreased bleb formation" EXACT []
synonym: "decreased cell blebbing" RELATED []
is_a: DDPHENO:0001049 ! aberrant bleb assembly

[Term]
id: DDPHENO:0001053
name: increased bleb assembly
def: "Increase in extent, amount, or degree of bleb assembly." [DDB:pf]
synonym: "increased bleb formation" EXACT []
synonym: "increased cell blebbing" RELATED []
is_a: DDPHENO:0001049 ! aberrant bleb assembly

[Term]
id: DDPHENO:0001054
name: increased number of early culminant tips
def: "Increase in extend, amount, or degree of the number of tips in early culminant." [DDB:pf]
synonym: "increased number of tip-organizer of the early culminant" EXACT []
synonym: "multiple tips in early culminant" EXACT []
is_a: DDPHENO:0000036 ! increased number of tip-organizers

[Term]
id: DDPHENO:0001055
name: increased number of mound tips
def: "Increase in extend, amount, or degree of the number of mound tips." [DDB:pf]
synonym: "" RELATED []
synonym: "multiple tips in mound" EXACT []
is_a: DDPHENO:0000036 ! increased number of tip-organizers

[Term]
id: DDPHENO:0001056
name: decreased actin filament polymerization
def: "Reduction in extent, amount, or degree of F-actin polymerization." [DDB:pg]
synonym: "decreased F-actin polymerization" EXACT []
is_a: DDPHENO:0001445 ! aberrant actin filament polymerization

[Term]
id: DDPHENO:0001057
name: abolished actin filament polymerization
def: "Complete inability to polymerize actin into F-actin." [DDB:pg]
synonym: "abolished F-actin polymerization" EXACT []
is_a: DDPHENO:0001445 ! aberrant actin filament polymerization

[Term]
id: DDPHENO:0001058
name: decreased protein kinase activation
def: "Reduction in extent, amount, or degree of activation of a protein kinase." [DDB:pg]
is_a: DDPHENO:0001119 ! aberrant regulation of protein kinase activity

[Term]
id: DDPHENO:0001059
name: obsolete abolished chemotaxis to cAMP during aggregation
def: "OBSOLETE. Complete inability for chemotaxis to cAMP during aggregation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001061
name: increased protein kinase activation
def: "Increase in extent, amount, or degree of activation of protein kinases." [DDB:pg]
is_a: DDPHENO:0001119 ! aberrant regulation of protein kinase activity

[Term]
id: DDPHENO:0001062
name: abolished protein kinase activation
def: "Complete inability for activation of protein kinases." [DDB:pg]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
is_a: DDPHENO:0001119 ! aberrant regulation of protein kinase activity

[Term]
id: DDPHENO:0001063
name: obsolete abolished myosin light chain kinase activation
def: "OBSOLETE. Complete inability for myosin light chain activation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001064
name: obsolete decreased myosin light chain kinase activation
def: "OBSOLETE. Reduction in extent, amount or degree of myosin light chain kinase activation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001065
name: obsolete increased myosin light chain kinase activation
def: "OBSOLETE. Increase in extent, amount, or degree of myosin light chain kinase activation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001066
name: aberrant contractile vacuole morphology
def: "Deviation from the normal, usual, or expected morphology of the vacuole." [DDB:pg]
is_a: DDPHENO:0000233 ! aberrant contractile vacuole organization
is_a: DDPHENO:0001002 ! aberrant organelle morphology

[Term]
id: DDPHENO:0001067
name: aberrant hyperosmotic response
def: "Deviation from the normal, usual, or expected events during the response to hyperosmotic stress." [DDB:pg]
synonym: "aberrant hypertonic response" EXACT []
synonym: "aberrant response to hyperosmotic stress" EXACT []
synonym: "aberrant response to hypertonic stress" EXACT []
is_a: DDPHENO:0000209 ! aberrant response to osmotic stress

[Term]
id: DDPHENO:0001068
name: aberrant hypotonic response
def: "Deviation from the normal, usual, or expected events during the response to hypo-osmotic stress." [DDB:pg]
comment: For example, when Dictyostelium cells are placed into water, they suffer from hypotonic stress and their contractile vacuole system allows them to survive for some time.
synonym: "aberrant response to hypo-osmotic stress" EXACT []
synonym: "aberrant response to hypotonic stress" EXACT []
is_a: DDPHENO:0000209 ! aberrant response to osmotic stress

[Term]
id: DDPHENO:0001069
name: delayed hyperosmotic response
def: "Late onset or slower progression in the response to hyperosmotic stress." [DDB:pg]
synonym: "delayed hypertonic response" EXACT []
synonym: "delayed response to hyperosmotic stress" EXACT []
is_a: DDPHENO:0001067 ! aberrant hyperosmotic response

[Term]
id: DDPHENO:0001070
name: precocious hyperosmotic response
def: "Early onset or faster progression in the response to hyperosmotic stress." [DDB:pg]
synonym: "precocious hypertonic response" EXACT []
synonym: "precocious response to hyperosmotic stress" EXACT []
is_a: DDPHENO:0001067 ! aberrant hyperosmotic response

[Term]
id: DDPHENO:0001071
name: precocious hypotonic response
def: "Early onset or faster progression in the response to hypo-osmotic stress." [DDB:pf]
synonym: "precocious response to hypo-osmotic stress" EXACT []
synonym: "precocious response to hypotonic stress" EXACT []
is_a: DDPHENO:0001068 ! aberrant hypotonic response

[Term]
id: DDPHENO:0001072
name: delayed hypotonic response
def: "Late onset or slower progression in the response to hypo-osmotic stress." [DDB:pg]
synonym: "delayed response to hypo-osmotic stress" EXACT []
synonym: "delayed response to hypotonic stress" EXACT []
is_a: DDPHENO:0001068 ! aberrant hypotonic response

[Term]
id: DDPHENO:0001074
name: aberrant osmosensory signaling pathway
def: "Deviation from the normal, usual, or expected events during the osmosensory signaling pathway." [DDB:pg]
is_a: DDPHENO:0001067 ! aberrant hyperosmotic response

[Term]
id: DDPHENO:0001075
name: decreased prestalk A cell differentiation
def: "Reduction in extent, amount, or degree of differentiation into prestalk A cells." [DDB:pg]
synonym: "decreased number of prestalk A cells" RELATED []
synonym: "decreased number of pstA cells" RELATED []
synonym: "decreased pstA cell differentiation" EXACT []
is_a: DDPHENO:0000098 ! aberrant prestalk A cell differentiation
is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation

[Term]
id: DDPHENO:0001076
name: abolished prestalk A cell differentiation
def: "Complete inability for differentiation of prestalk A cells." [DDB:pg]
synonym: "abolished pstA cell differentiation" EXACT []
is_a: DDPHENO:0000098 ! aberrant prestalk A cell differentiation
is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation

[Term]
id: DDPHENO:0001077
name: aberrant slug migration
def: "Deviation from the normal, usual, or expected events during slug migration." [DDB:kp]
synonym: "aberrant migratory slug locomotion" EXACT []
is_a: DDPHENO:0001014 ! aberrant slug development

[Term]
id: DDPHENO:0001078
name: aberrant mitochondrion morphology
def: "Deviation from the normal, usual, or expected morphology of the mitochondrion." [DDB:pg]
synonym: "aberrant mitochondrial morphology" EXACT []
is_a: DDPHENO:0001002 ! aberrant organelle morphology
is_a: DDPHENO:0001234 ! aberrant mitochondrion organization

[Term]
id: DDPHENO:0001079
name: obsolete decreased number of tubular mitochondria
def: "OBSOLETE. Quantitative decrease in tubular mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001080
name: abolished aggregation
def: "Complete inability for aggregation." [DDB:pg]
synonym: "abolished aggregation during fruiting body development" EXACT []
synonym: "abolished aggregation involved in sorocarp development" EXACT []
synonym: "agg-" EXACT []
is_a: DDPHENO:0000483 ! aberrant aggregation

[Term]
id: DDPHENO:0001081
name: obsolete decreased number of spherical mitochondria
def: "OBSOLETE. Quantitative decrease in spherical mitochondria." [DDB:pg]
comment: In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular.
is_obsolete: true

[Term]
id: DDPHENO:0001082
name: obsolete increased number of spherical mitochondria
def: "OBSOLETE. Quantitative increase in spherical mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001083
name: obsolete decreased number of rod-shaped mitochondria
def: "OBSOLETE. Quantitative decrease in rod-shaped mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001084
name: aberrant vegetative growth
def: "Deviation from the normal, usual, or expected events during vegetative growth." [DDB:pg]
synonym: "aberrant asexual reproduction" EXACT []
synonym: "aberrant cell proliferation" RELATED []
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001085
name: obsolete increased number of rod-shaped mitochondria
def: "OBSOLETE. Quantitative increase in rod-shaped mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001086
name: increased chemotaxis to cAMP
def: "Increase in extent, amount, or degree of chemotaxis in response to cAMP." [DDB:pf]
synonym: "increased positive chemotaxis to cAMP" EXACT []
is_a: DDPHENO:0000400 ! increased chemotaxis rate
is_a: DDPHENO:0001167 ! aberrant chemotaxis to cAMP

[Term]
id: DDPHENO:0001087
name: increased chemotaxis to folate
def: "Increase in extent, amount, or degree of chemotaxis in response to folate." [DDB:pf]
synonym: "increased chemotaxis to folic acid" EXACT []
synonym: "increased positive chemotaxis to folate" EXACT []
synonym: "increased positive chemotaxis to folic acid" EXACT []
is_a: DDPHENO:0000400 ! increased chemotaxis rate
is_a: DDPHENO:0001168 ! aberrant chemotaxis to folate

[Term]
id: DDPHENO:0001088
name: aberrant response to DIF-1
def: "Deviation from the normal, usual, or expected during the response to differentiation inducing factor 1." [DDB:pg]
synonym: "aberrant response to differentiation inducing factor 1" EXACT []
is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus

[Term]
id: DDPHENO:0001090
name: decreased response to DIF-1
def: "Reduction in extent, amount, or degree of the response to DIF-1." [DDB:pg]
synonym: "decreased response to differentiation inducing factor 1" EXACT []
is_a: DDPHENO:0001088 ! aberrant response to DIF-1

[Term]
id: DDPHENO:0001091
name: increased response to DIF-1
def: "Increase in extent, amount, or degree of response to DIF-1." [DDB:pg]
synonym: "increased response to differentiation inducing factor 1" EXACT []
is_a: DDPHENO:0001088 ! aberrant response to DIF-1

[Term]
id: DDPHENO:0001092
name: abolished response to DIF-1
def: "Complete inability for response to DIF-1." [DDB:pg]
synonym: "abolished response to differentiation inducing factor 1" EXACT []
is_a: DDPHENO:0000693 ! abolished response to biotic stimulus
is_a: DDPHENO:0001088 ! aberrant response to DIF-1

[Term]
id: DDPHENO:0001093
name: delayed response to DIF-1
def: "Late onset or slower progression in the response to DIF-1." [DDB:pg]
synonym: "delayed response to differentiation inducing factor 1" EXACT []
is_a: DDPHENO:0001088 ! aberrant response to DIF-1

[Term]
id: DDPHENO:0001094
name: precocious response to DIF-1
def: "Early onset or faster progression in the response to DIF-1." [DDB:pg]
synonym: "precocious response to differentiation inducing factor 1" EXACT []
is_a: DDPHENO:0001088 ! aberrant response to DIF-1

[Term]
id: DDPHENO:0001095
name: aberrant DIF-1 biosynthesis
def: "Deviation from the normal, usual, or expected in the DIF-1 biosynthesis." [DDB:pf]
synonym: "aberrant DIF-1 biosynthetic process" EXACT []
synonym: "aberrant DIF-1 production" RELATED []
synonym: "aberrant differentiation inducing factor 1 biosynthesis" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001097
name: decreased DIF-1 biosynthesis
def: "Reduction in extent, amount, or degree for DIF-1 biosynthesis." [DDB:pf]
synonym: "decreased DIF-1 biosynthetic process" EXACT []
synonym: "decreased DIF-1 production" RELATED []
synonym: "decreased differentiation inducing factor 1 biosynthesis" EXACT []
is_a: DDPHENO:0001095 ! aberrant DIF-1 biosynthesis

[Term]
id: DDPHENO:0001098
name: increased DIF-1 biosynthesis
def: "Increase in extent, amount, or degree for DIF-1 biosynthesis." [DDB:pf]
synonym: "increased DIF-1 biosynthetic process" EXACT []
synonym: "increased DIF-1 production" RELATED []
synonym: "increased differentiation inducing factor 1 biosynthesis" EXACT []
is_a: DDPHENO:0001095 ! aberrant DIF-1 biosynthesis

[Term]
id: DDPHENO:0001099
name: obsolete delayed DIF production
def: "OBSOLETE. Late onset or slower progression for DIF production." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001100
name: obsolete precocious DIF production
def: "OBSOLETE. Complete inability for DIF production." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001101
name: abolished chemotaxis to cAMP
def: "Complete inability for chemotaxis in response to cAMP." [DDB:pf]
synonym: "abolished positive chemotaxis to cAMP" EXACT []
is_a: DDPHENO:0000466 ! abolished positive chemotaxis
is_a: DDPHENO:0001167 ! aberrant chemotaxis to cAMP

[Term]
id: DDPHENO:0001102
name: abolished chemotaxis to folate
def: "Complete inability for chemotaxis in response to folate." [DDB:pf]
synonym: "abolished chemotaxis to folic acid" EXACT [DDB:kp]
synonym: "abolished positive chemotaxis to folate" RELATED []
synonym: "abolished positive chemotaxis to folic acid" EXACT []
is_a: DDPHENO:0000466 ! abolished positive chemotaxis
is_a: DDPHENO:0001168 ! aberrant chemotaxis to folate

[Term]
id: DDPHENO:0001103
name: decreased culmination
def: "Reduction in extent, amount, or degree of culminants, resulting in fewer fruiting bodies." [DDB:pf]
synonym: "decreased culmination involved in sorocarp development" EXACT []
synonym: "decreased number of fruiting bodies" RELATED []
is_a: DDPHENO:0001015 ! aberrant culmination

[Term]
id: DDPHENO:0001104
name: increased culmination
def: "Increase in extent, amount, or degree of culminants, resulting in more fruiting bodies." [DDB:pf]
synonym: "increased culmination involved in sorocarp development" EXACT []
synonym: "increased number of fruiting bodies" RELATED []
is_a: DDPHENO:0001015 ! aberrant culmination

[Term]
id: DDPHENO:0001105
name: aberrant catalytic activity
def: "Deviation from the normal, usual, or expected activity of a catalyst." [DDB:pf]
synonym: "aberrant enzyme activity" NARROW [DDB:kp]
is_a: DDPHENO:0001171 ! aberrant molecular function

[Term]
id: DDPHENO:0001106
name: decreased lysosomal protein degradation
def: "Reduction in extent, amount, or degree of lysosomal protein degradation." [DDB:pf]
synonym: "decreased lysosomal enzyme activity" RELATED []
synonym: "decreased lysosomal protein catabolic process" RELATED []
is_a: DDPHENO:0001257 ! decreased catalytic activity

[Term]
id: DDPHENO:0001107
name: increased lysosomal protein degradation
def: "Increase in extent, amount, or degree of lysosomal protein degradation." [DDB:pf]
synonym: "increased lysosomal enzyme activity" RELATED []
synonym: "increased lysosomal protein catabolic process" RELATED []
is_a: DDPHENO:0001256 ! increased catalytic activity

[Term]
id: DDPHENO:0001108
name: aberrant response to lithium
def: "Deviation from the normal, usual, or expected events during the response to lithium." [DDB:pf]
is_a: DDPHENO:0000040 ! aberrant response to chemical

[Term]
id: DDPHENO:0001109
name: aberrant response to valproic acid
def: "Deviation from the normal, usual, or expected events during the response to valproic acid." [DDB:pf]
synonym: "aberrant response to VPA" RELATED []
is_a: DDPHENO:0000040 ! aberrant response to chemical

[Term]
id: DDPHENO:0001110
name: aberrant exocytosis
def: "Deviation from the normal, usual, or expected events during exocytosis." [DDB:pf]
is_a: DDPHENO:0001047 ! aberrant transport

[Term]
id: DDPHENO:0001111
name: decreased exocytosis
def: "Reduction in extent, amount, or degree of exocytosis." [DDB:pf]
is_a: DDPHENO:0001110 ! aberrant exocytosis

[Term]
id: DDPHENO:0001112
name: increased exocytosis
def: "Increase in extent, amount, or degree of exocytosis." [DDB:pf]
is_a: DDPHENO:0001110 ! aberrant exocytosis

[Term]
id: DDPHENO:0001113
name: aberrant gene expression
alt_id: DDPHENO:0001000
alt_id: DDPHENO:0001089
def: "Deviation from the normal, usual, or expected expression of genes." [DDB:kp]
synonym: "aberrant expression of post aggregation-specific genes" NARROW []
synonym: "merged_aberrant expression of aggregation genes" NARROW [DDB:kp]
synonym: "merged_aberrant expression of post-aggregative genes" NARROW [DDB:kp]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001114
name: abolished gene expression
alt_id: DDPHENO:0000299
alt_id: DDPHENO:0000515
def: "Complete inability for expression of genes." [DDB:kp]
synonym: "merged_abolished expression of post-aggregative genes" NARROW [DDB:kp]
synonym: "merged_abolished expression of prespore genes" NARROW [DDB:kp]
is_a: DDPHENO:0001113 ! aberrant gene expression

[Term]
id: DDPHENO:0001115
name: delayed gene expression
alt_id: DDPHENO:0000179
alt_id: DDPHENO:0000268
alt_id: DDPHENO:0000470
alt_id: DDPHENO:0000485
def: "Late onset or slower progression in the expression of genes." [DDB:kp]
synonym: "merged_delayed expression of aggregation genes" NARROW [DDB:kp]
synonym: "merged_delayed expression of post-aggregative genes" NARROW [DDB:kp]
synonym: "merged_delayed expression of prespore genes" NARROW [DDB:kp]
synonym: "merged_delayed expression of prestalk genes" NARROW [DDB:kp]
is_a: DDPHENO:0001113 ! aberrant gene expression

[Term]
id: DDPHENO:0001116
name: precocious gene expression
alt_id: DDPHENO:0000180
alt_id: DDPHENO:0000217
alt_id: DDPHENO:0000218
alt_id: DDPHENO:0001073
def: "Early onset or faster progression in the expression of genes." [DDB:kp]
synonym: "merged_precocious expression of aggregation genes" NARROW [DDB:kp]
synonym: "merged_precocious expression of post-aggregative genes" NARROW [DDB:kp]
synonym: "merged_precocious expression of prespore genes" NARROW [DDB:kp]
synonym: "merged_precocious expression of prestalk genes" NARROW [DDB:kp]
is_a: DDPHENO:0001113 ! aberrant gene expression

[Term]
id: DDPHENO:0001117
name: obsolete mislocalized gene expression
alt_id: DDPHENO:0000182
alt_id: DDPHENO:0000219
def: "OBSOLETE. Gene expression occurring in an abnormal position or in an unusual manner or form." [DDB:kp]
is_obsolete: true

[Term]
id: DDPHENO:0001118
name: aberrant signal transduction
def: "Deviation from the normal, usual, or expected events during signal transduction." [DDB:pg]
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001119
name: aberrant regulation of protein kinase activity
def: "Deviation from the normal, usual, or expected events during the regulation of protein kinase activity." [DDB:pg]
is_a: DDPHENO:0001303 ! aberrant regulation of catalytic activity

[Term]
id: DDPHENO:0001120
name: obsolete abolished protein kinase B activation
def: "OBSOLETE. Complete inability for protein kinase B activation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001121
name: aberrant taxis
def: "Deviation from the normal, usual, or expected events during the response to an external stimulus." [DDB:pg]
is_a: DDPHENO:0001003 ! aberrant response to stimulus

[Term]
id: DDPHENO:0001122
name: aberrant chemotaxis
def: "Deviation from the normal, usual, or expected events during the locomotory response to a chemical concentration gradient." [DD:pg]
is_a: DDPHENO:0000040 ! aberrant response to chemical
is_a: DDPHENO:0000264 ! aberrant cell motility
is_a: DDPHENO:0001121 ! aberrant taxis

[Term]
id: DDPHENO:0001123
name: increased phototaxis
def: "Increase in extent, amount, or degree of phototaxis." [DDB:pg]
is_a: DDPHENO:0000222 ! aberrant phototaxis
is_a: DDPHENO:0001129 ! increased taxis

[Term]
id: DDPHENO:0001124
name: increased thermotaxis
def: "Increase in extent, amount, or degree of thermotaxis." [DDB:pg]
is_a: DDPHENO:0000223 ! aberrant thermotaxis
is_a: DDPHENO:0001129 ! increased taxis

[Term]
id: DDPHENO:0001125
name: abolished phototaxis
def: "Complete inability for phototaxis." [DDB:pg]
is_a: DDPHENO:0000222 ! aberrant phototaxis
is_a: DDPHENO:0001131 ! abolished taxis

[Term]
id: DDPHENO:0001126
name: abolished thermotaxis
def: "Complete inability for thermotaxis." [DDB:pg]
is_a: DDPHENO:0000223 ! aberrant thermotaxis
is_a: DDPHENO:0001131 ! abolished taxis

[Term]
id: DDPHENO:0001127
name: decreased phototaxis
def: "Reduction in extent, amount, or degree of phototaxis." [DDB:pg]
is_a: DDPHENO:0000222 ! aberrant phototaxis
is_a: DDPHENO:0001130 ! decreased taxis

[Term]
id: DDPHENO:0001128
name: decreased thermotaxis
def: "Reduction in extent, amount, or degree of thermotaxis." [DDB:pg]
is_a: DDPHENO:0000223 ! aberrant thermotaxis
is_a: DDPHENO:0001130 ! decreased taxis

[Term]
id: DDPHENO:0001129
name: increased taxis
def: "Increase in extent, amount, or degree of the response to an external stimulus." [DDB:pg]
is_a: DDPHENO:0001121 ! aberrant taxis

[Term]
id: DDPHENO:0001130
name: decreased taxis
def: "Reduction in extent, amount, or degree of the response to external stimulus." [DDB:pg]
is_a: DDPHENO:0001121 ! aberrant taxis

[Term]
id: DDPHENO:0001131
name: abolished taxis
def: "Complete inability to respond to an external stimulus." [DDB:pg]
is_a: DDPHENO:0001121 ! aberrant taxis

[Term]
id: DDPHENO:0001132
name: decreased activation of adenylate cyclase activity
def: "Reduction in extent, amount, or degree of activation of adenylate cyclase." [DDB:pg]
synonym: "decreased activation of ACA" EXACT []
is_a: DDPHENO:0000198 ! aberrant activation of adenylate cyclase activity

[Term]
id: DDPHENO:0001133
name: abolished activation of adenylate cyclase activity
def: "Complete inability to activate adenylate cyclase upon stimulus." [DDB:pg]
synonym: "abolished activation of ACA" EXACT []
is_a: DDPHENO:0000198 ! aberrant activation of adenylate cyclase activity

[Term]
id: DDPHENO:0001134
name: increased activation of adenylate cyclase activity
def: "Increase in extent, amount, or degree of activation of adenylate cyclase." [DDB:pg]
synonym: "increased activation of ACA" EXACT []
is_a: DDPHENO:0000198 ! aberrant activation of adenylate cyclase activity

[Term]
id: DDPHENO:0001135
name: obsolete abolished chemoattractant-mediated F-actin polymerization
def: "OBSOLETE. Complete inability for chemoattractant-mediated F-actin polymerization." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001136
name: obsolete increased chemoattractant-mediated F-actin polymerization
def: "OBSOLETE. Increase in extent, amount, or degree of chemoattractant-mediated F-actin polymerization." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001137
name: aberrant regulation of GTPase activity
def: "Deviation from the normal, usual, or expected events during the regulation of the activity of a GTPase." [DDB:pg]
is_a: DDPHENO:0001303 ! aberrant regulation of catalytic activity

[Term]
id: DDPHENO:0001138
name: decreased positive regulation of GTPase activity
def: "Reduction in extent, amount, or degree of positive regulation of GTPase activity." [DDB:pg]
is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity

[Term]
id: DDPHENO:0001139
name: increased positive regulation of GTPase activity
def: "Increase in extent, amount, or degree of positive regulation of GTPase activity." [DDB:pg]
is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity

[Term]
id: DDPHENO:0001140
name: obsolete aberrant regulation of Ras GTPase activity
def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Ras GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001141
name: obsolete aberrant regulation of Rac GTPase activity
def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Rac GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001142
name: obsolete aberrant regulation of Rab GTPase activity
def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Rab GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001143
name: obsolete aberrant regulation of Ran GTPase activity
def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Ran GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001144
name: obsolete aberrant regulation of Rap GTPase activity
def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Rap GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001145
name: obsolete decreased positive regulation of Rab GTPase activity
def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Rab GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001146
name: obsolete increased positive regulation of Rab GTPase activity
def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Rab GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001147
name: obsolete decreased positive regulation of Rac GTPase activity
def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Rac GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001148
name: obsolete increased positive regulation of Rac GTPase activity
def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Rac GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001149
name: obsolete decreased positive regulation of Ran GTPase activity
def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Ran GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001150
name: obsolete increased positive regulation of Ran GTPase activity
def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Ran GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001151
name: obsolete decreased positive regulation of Rap GTPase activity
def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Rap GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001152
name: obsolete increased positive regulation of Rap GTPase activity
def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Rap GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001153
name: obsolete increased positive regulation of Ras GTPase activity
def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Ras GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001154
name: obsolete decreased positive regulation of Ras GTPase activity
def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Ras GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001155
name: aberrant macromolecule biosynthesis
def: "Deviation from the normal, usual, or expected events during macromolecule biosynthesis." [DDB:pg]
synonym: "aberrant macromolecule biosynthetic process" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001156
name: aberrant cellulose biosynthesis
def: "Deviation from the normal, usual, or expected events during cellulose biosynthesis." [DDB:pg]
synonym: "aberrant cellulose biosynthetic process" EXACT []
is_a: DDPHENO:0001155 ! aberrant macromolecule biosynthesis

[Term]
id: DDPHENO:0001157
name: abolished cellulose biosynthesis
def: "Complete inability for cellulose biosynthesis." [DDB:pg]
synonym: "abolished cellulose biosynthetic process" EXACT []
is_a: DDPHENO:0001156 ! aberrant cellulose biosynthesis

[Term]
id: DDPHENO:0001158
name: increased cellulose biosynthesis
def: "Increase in extent, amount, or degree of cellulose biosynthesis." [DDB:pg]
synonym: "increased cellulose biosynthetic process" EXACT []
is_a: DDPHENO:0001156 ! aberrant cellulose biosynthesis

[Term]
id: DDPHENO:0001159
name: decreased cellulose biosynthesis
def: "Reduction in extent, amount, or degree of cellulose biosynthesis." [DDB:pg]
synonym: "decreased cellulose biosynthetic process" EXACT []
is_a: DDPHENO:0001156 ! aberrant cellulose biosynthesis

[Term]
id: DDPHENO:0001160
name: abolished superoxide generation
def: "Complete inability for superoxide generation." [DDB:pf]
synonym: "abolished superoxide anion generation" EXACT []
synonym: "abolished superoxide production" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001161
name: decreased superoxide generation
def: "Reduction in extent, amount, or degree of superoxide generation." [DDB:pf]
synonym: "decreased superoxide anion generation" EXACT []
synonym: "decreased superoxide production" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001162
name: increased superoxide generation
def: "Increase in amount or generation of superoxide." [DDB:pf]
synonym: "increased superoxide anion generation" EXACT []
synonym: "increased superoxide production" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001163
name: aberrant prestalk B cell differentiation
def: "Deviation from the normal, usual, or expected events during differentiation of prestalk B cells." [DDB:pg]
synonym: "aberrant pstB cell differentiation" EXACT []
is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation

[Term]
id: DDPHENO:0001164
name: abolished prestalk B cell differentiation
def: "Complete inability for differentiation of prestalk B cells." [DDB:pg]
synonym: "abolished pstB cell differentiation" EXACT []
is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation
is_a: DDPHENO:0001163 ! aberrant prestalk B cell differentiation

[Term]
id: DDPHENO:0001165
name: decreased prestalk B cell differentiation
def: "Reduction in extent, amount, or degree of differentiation into prestalk B cells." [DDB:pg]
synonym: "decreased number of prestalk B cells" RELATED []
synonym: "decreased number of pstB cells" RELATED []
synonym: "decreased pstB cell differentiation" EXACT []
is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation
is_a: DDPHENO:0001163 ! aberrant prestalk B cell differentiation

[Term]
id: DDPHENO:0001166
name: increased prestalk B cell differentiation
def: "Increase in extent, amount, or degree of differentiation into prestalk B cells." [DDB:pg]
synonym: "increased number of prestalk B cells" RELATED []
synonym: "increased number of pstB cells" RELATED []
synonym: "increased pstB cell differentiation" EXACT []
is_a: DDPHENO:0000169 ! increased prestalk cell differentiation
is_a: DDPHENO:0001163 ! aberrant prestalk B cell differentiation

[Term]
id: DDPHENO:0001167
name: aberrant chemotaxis to cAMP
def: "Deviation from the normal, usual, or expected events during the locomotory response to cAMP." [DDB:kp]
synonym: "aberrant positive chemotaxis to cAMP" EXACT []
is_a: DDPHENO:0001224 ! aberrant positive chemotaxis

[Term]
id: DDPHENO:0001168
name: aberrant chemotaxis to folate
def: "Deviation from the normal, usual, or expected events during the locomotory response to folate (folic acid)." [DDB:kp]
synonym: "aberrant chemotaxis to folic acid" EXACT [DDB:kp]
synonym: "aberrant positive chemotaxis to folate" EXACT []
synonym: "aberrant positive chemotaxis to folic acid" EXACT []
is_a: DDPHENO:0001224 ! aberrant positive chemotaxis

[Term]
id: DDPHENO:0001169
name: delayed cytokinesis
def: "Late onset or slower progression through cytokinesis." [DDB:pf]
is_a: DDPHENO:0000149 ! aberrant cytokinesis

[Term]
id: DDPHENO:0001170
name: aberrant cytokinesis, contractile ring contraction
def: "Deviation from the normal, usual, or expected events during contractile ring contraction during cytokinesis." [DDB:pf]
is_a: DDPHENO:0000149 ! aberrant cytokinesis

[Term]
id: DDPHENO:0001171
name: aberrant molecular function
def: "Deviation from normal, usual, or expected molecular function." [DDB:kp]
is_a: DDPHENO:0010000 ! Dicty Phenotypes

[Term]
id: DDPHENO:0001172
name: increased guanyl-nucleotide exchange factor activity
def: "Increase in extent, amount, or degree of guanyl-nucleotide exchange factor activity." [DDB:pf]
synonym: "increased GEF activity" EXACT []
is_a: DDPHENO:0001256 ! increased catalytic activity

[Term]
id: DDPHENO:0001173
name: obsolete aberrant aspidocyte differentiation
def: "OBSOLETE. Deviation from the normal, usual, or expected events during aspidocyte differentiation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001174
name: increased cell differentiation
def: "Increase in extent, amount, or degree of cell differentiation." [DDB:pf]
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0001175
name: decreased cell differentiation
def: "Decrease in extent, amount, or degree of cell differentiation." [DDB:pf]
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0001176
name: abolished cell differentiation
def: "Complete inability for cell differentiation." [DDB:pf]
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0001177
name: decreased pseudopodium formation
def: "Decrease in extent, amount, or degree of formation of pseudopods." [DDB:pg]
synonym: "decreased pseudopod extension" RELATED []
synonym: "decreased pseudopodium assembly" EXACT []
is_a: DDPHENO:0001027 ! aberrant pseudopodium formation

[Term]
id: DDPHENO:0001178
name: decreased pseudopodium size
def: "Reduction in relative or proportionate dimensions of the pseudopodium." [DDB:pf]
is_a: DDPHENO:0001027 ! aberrant pseudopodium formation

[Term]
id: DDPHENO:0001179
name: decreased F-actin polymerization at the leading edge
def: "Reduction in extent, amount, or degree of F-actin polymerization in the area closest to the direction of movement in a motile cell." [DDB:pf]
synonym: "decreased filamentous actin polymerization at leading edge" EXACT []
is_a: DDPHENO:0001056 ! decreased actin filament polymerization

[Term]
id: DDPHENO:0001180
name: increased F-actin polymerization at the leading edge
def: "Increase in extent, amount, or degree of F-actin polymerization in the area closest to the direction of movement in a motile cell." [DDB:pf]
synonym: "increased filamentous actin polymerization at leading edge" EXACT []
is_a: DDPHENO:0000459 ! increased actin filament polymerization

[Term]
id: DDPHENO:0001181
name: delayed pseudopodium formation
def: "Late onset or slower progression during pseudopodium formation." [DDB:pf]
synonym: "delayed pseudopod extension" RELATED []
synonym: "delayed pseudopodium assembly" EXACT []
is_a: DDPHENO:0001027 ! aberrant pseudopodium formation

[Term]
id: DDPHENO:0001182
name: decreased spore size
def: "Decrease in relative or proportionate dimensions of the spore." [DDB:pg]
synonym: "small spores" RELATED []
is_a: DDPHENO:0000163 ! aberrant spore morphology

[Term]
id: DDPHENO:0001183
name: increased spore size
def: "Increase in relative or proportionate dimensions of the spore." [DDB:pg]
synonym: "large spores" RELATED []
is_a: DDPHENO:0000163 ! aberrant spore morphology

[Term]
id: DDPHENO:0001184
name: decreased myo-inositol level
def: "Decrease in amount or accumulation of intracellular myo-inositol." [DDB:pg]
synonym: "decreased cytosolic myo-inositol level" EXACT []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0001185
name: increased myo-inositol level
def: "Increase in amount or accumulation of intracellular myo-inositol." [DDB:pg]
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0001186
name: increased 2,3-bisphosphoglycerate level
def: "Increase in amount or accumulation of intracellular 2,3-bisphosphoglycerate." [DDB:pg]
synonym: "increased 2,3-BPG" EXACT []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0001187
name: decreased 2,3-bisphosphoglycerate level
def: "Reduction in amount or accumulation of intracellular 2,3-bisphosphoglycerate." [DDB:pg]
synonym: "decreased 2,3-BPG" EXACT []
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001188
name: abolished macroautophagy
def: "Complete inability for macroautophagy." [DDB:pf]
is_a: DDPHENO:0000212 ! aberrant macroautophagy

[Term]
id: DDPHENO:0001189
name: decreased macroautophagy
def: "Reduction in extent, amount, or degree of macroautophagy." [DDB:pf]
is_a: DDPHENO:0000212 ! aberrant macroautophagy

[Term]
id: DDPHENO:0001190
name: increased macroautophagy
def: "Increase in extent, amount, or degree of macroautophagy." [DDB:pf]
is_a: DDPHENO:0000212 ! aberrant macroautophagy

[Term]
id: DDPHENO:0001191
name: increased number of autophagosomes
def: "Quantitative increase in autophagosomes." [DDB:pf]
synonym: "increased number of autophagic vacuoles" EXACT []
is_a: DDPHENO:0001041 ! aberrant vacuole organization

[Term]
id: DDPHENO:0001192
name: decreased number of autophagosomes
def: "Quantitative reduction in autophagosomes." [DDB:pf]
synonym: "decreased number of autophagic vacuoles" EXACT []
is_a: DDPHENO:0001279 ! decreased autophagic vacuole organization

[Term]
id: DDPHENO:0001193
name: obsolete aberrant infection rate by a microorganism
def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001194
name: obsolete increased infection rate by a microorganism
def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001195
name: obsolete decreased infection rate by a microorganism
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0001196
name: obsolete decreased infection rate by Mycobacterium avium
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0001197
name: obsolete decreased infection rate by Cryptococcus neoformans
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0001198
name: obsolete increased infection rate by Cryptococcus neoformans
def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001199
name: obsolete decreased actin-dependent ATPase activity
def: "OBSOLETE. Reduction in extent, amount, or degree of decreased actin-dependent ATPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001200
name: obsolete increased actin-dependent ATPase activity
def: "OBSOLETE. Increase in extent, amount, or degree of increased actin-dependent ATPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001201
name: decreased actin filament sliding
def: "Reduction in amount or accumulation of actin filament sliding." [DDB:pf]
synonym: "decreased actin-myosin filament sliding" EXACT []
synonym: "decreased F-actin sliding" EXACT []
is_a: DDPHENO:0000151 ! aberrant actin filament organization

[Term]
id: DDPHENO:0001202
name: increased actin filament sliding
def: "Increased in extent, amount, or degree of F-actin filament sliding." [DDB:pf]
synonym: "increased actin-myosin filament sliding" EXACT []
synonym: "increased F-actin sliding" EXACT []
is_a: DDPHENO:0000151 ! aberrant actin filament organization

[Term]
id: DDPHENO:0001203
name: aberrant response to nutrients
def: "Deviation from the normal, usual, or expected events during the response to nutrients." [DDB:pf]
is_a: DDPHENO:0000040 ! aberrant response to chemical

[Term]
id: DDPHENO:0001204
name: increased endosome size
def: "Increase in relative or proportionate dimensions of the endosome." [DDB:pg]
is_a: DDPHENO:0000230 ! aberrant endosome morphology

[Term]
id: DDPHENO:0001205
name: decreased endosome size
def: "Decrease in relative or proportionate dimensions of the endosome." [DDB:pg]
is_a: DDPHENO:0000230 ! aberrant endosome morphology

[Term]
id: DDPHENO:0001206
name: aberrant lysosome morphology
def: "Deviation from the normal, usual, or expected morphology of the lysosome." [DDB:pf]
is_a: DDPHENO:0000230 ! aberrant endosome morphology

[Term]
id: DDPHENO:0001207
name: decreased lysosome size
def: "Decrease in relative or proportionate dimensions of the lysosome." [DDB:pg]
is_a: DDPHENO:0001205 ! decreased endosome size
is_a: DDPHENO:0001206 ! aberrant lysosome morphology

[Term]
id: DDPHENO:0001208
name: increased lysosome size
def: "Increase in relative or proportionate dimensions of the lysosome." [DDB:pg]
is_a: DDPHENO:0001204 ! increased endosome size
is_a: DDPHENO:0001206 ! aberrant lysosome morphology

[Term]
id: DDPHENO:0001209
name: aberrant translation
def: "Deviation from the normal, usual, or expected events during translation." [DDB:pg]
synonym: "aberrant protein biosynthesis" EXACT []
synonym: "aberrant protein synthesis" EXACT []
synonym: "aberrant protein translation" EXACT []
is_a: DDPHENO:0001155 ! aberrant macromolecule biosynthesis

[Term]
id: DDPHENO:0001210
name: abolished translation
def: "Complete inability for translation." [DDB:pg]
synonym: "abolished protein biosynthesis" EXACT []
synonym: "abolished protein synthesis" EXACT []
synonym: "abolished protein translation" EXACT []
is_a: DDPHENO:0001209 ! aberrant translation

[Term]
id: DDPHENO:0001211
name: decreased translation
def: "Reduction in extent, amount, or degree of translation." [DDB:pg]
synonym: "decreased protein biosynthesis" EXACT []
synonym: "decreased protein synthesis" EXACT []
synonym: "decreased protein translation" EXACT []
is_a: DDPHENO:0001209 ! aberrant translation

[Term]
id: DDPHENO:0001212
name: increased translation
def: "Increase in extent, amount, or degree of translation." [DDB:pg]
synonym: "increased protein biosynthesis" EXACT []
synonym: "increased protein synthesis" EXACT []
synonym: "increased protein translation" EXACT []
is_a: DDPHENO:0001209 ! aberrant translation

[Term]
id: DDPHENO:0001213
name: decreased calcium-dependent cell-cell adhesion
def: "Reduction in extent, amount, or degree of calcium-dependent cell-cell adhesion." [DDB:pf]
synonym: "decreased calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT []
synonym: "decreased EDTA-sensitive cell-cell adhesion" RELATED []
is_a: DDPHENO:0000138 ! decreased cell-cell adhesion

[Term]
id: DDPHENO:0001214
name: decreased calcium-independent cell-cell adhesion
def: "Reduction in extent, amount, or degree of calcium-independent cell-cell adhesion." [DDB:pf]
synonym: "decreased calcium-independent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT []
synonym: "decreased EDTA-resistant cell-cell adhesion" RELATED []
is_a: DDPHENO:0000138 ! decreased cell-cell adhesion

[Term]
id: DDPHENO:0001215
name: increased calcium-dependent cell-cell adhesion
def: "Increase in extent, amount, or degree of calcium-dependent cell-cell adhesion." [DDB:pf]
synonym: "increased calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT []
synonym: "increased EDTA-sensitive cell-cell adhesion" RELATED []
is_a: DDPHENO:0000109 ! increased cell-cell adhesion

[Term]
id: DDPHENO:0001216
name: increased calcium-independent cell-cell adhesion
def: "Increase in extent, amount, or degree of calcium-independent cell-cell adhesion." [DDB:pf]
synonym: "increased calcium-independent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT []
synonym: "increased EDTA-resistant cell-cell adhesion" RELATED []
is_a: DDPHENO:0000109 ! increased cell-cell adhesion

[Term]
id: DDPHENO:0001217
name: aberrant cellular localization
def: "Deviation from the normal, usual, or expected events during localization within the cell." [DDB:pf]
comment: Use for mutated gene products that do not localize to their typical cellular compartment compared to the wild type gene product.
is_a: DDPHENO:0001009 ! aberrant localization

[Term]
id: DDPHENO:0001218
name: aberrant organelle localization
def: "Deviation from the normal, usual, or expected localization of an organelle within the cell." [DDB:pf]
is_a: DDPHENO:0001217 ! aberrant cellular localization

[Term]
id: DDPHENO:0001219
name: aberrant Golgi localization
def: "Deviation from the normal, usual, or expected localization of the Golgi apparatus." [DDB:pg]
is_a: DDPHENO:0001218 ! aberrant organelle localization

[Term]
id: DDPHENO:0001220
name: aberrant nucleus localization
def: "Deviation from the normal, usual, or expected localization of the nucleus." [DDB:pg]
is_a: DDPHENO:0001218 ! aberrant organelle localization

[Term]
id: DDPHENO:0001221
name: aberrant centrosome localization
def: "Deviation from the normal, usual, or expected localization of the centrosome." [DDB:pg]
is_a: DDPHENO:0001218 ! aberrant organelle localization

[Term]
id: DDPHENO:0001222
name: aberrant phagolysosome formation
def: "Deviation from the normal, usual, or expected events during phagolysosome formation." [DDB:pf]
synonym: "aberrant late phagosome formation" RELATED []
synonym: "aberrant phagolysosome assembly" EXACT []
is_a: DDPHENO:0001006 ! aberrant phagocytosis

[Term]
id: DDPHENO:0001223
name: decreased phagolysosome formation
def: "Reduction in extent, amount, or degree of phagolysosome formation." [DDB:pf]
synonym: "decreased late phagosome formation" RELATED []
synonym: "decreased phagolysosome assembly" EXACT []
is_a: DDPHENO:0001222 ! aberrant phagolysosome formation

[Term]
id: DDPHENO:0001224
name: aberrant positive chemotaxis
def: "Deviation from the normal, usual, or expected events during the locomotory response guided by increasing chemical concentration gradient." [DDB:pg]
is_a: DDPHENO:0001122 ! aberrant chemotaxis

[Term]
id: DDPHENO:0001225
name: aberrant negative chemotaxis
def: "Deviation from the normal, usual, or expected events during the locomotory response towards a decreasing chemical concentration." [DDB:pf]
synonym: "aberrant chemorepulsion" EXACT []
is_a: DDPHENO:0001122 ! aberrant chemotaxis

[Term]
id: DDPHENO:0001226
name: aberrant cellular response to extracellular stimulus
def: "Deviation from the normal, usual, or expected during the cellular response to extracellular stimulus." [DDB:pg]
is_a: DDPHENO:0001003 ! aberrant response to stimulus

[Term]
id: DDPHENO:0001227
name: obsolete aberrant response to prestarvation factor
def: "OBSOLETE. Deviation from the normal, usual, or expected events during the response to prestarvation factor (PSF) found in conditioned media (CM)." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001228
name: obsolete aberrant detection of prestarvation factor
def: "OBSOLETE. Deviation from the normal, usual, or expected events during the detection of prestarvation factor (PSF) found in conditioned media (CM)." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001229
name: decreased 3',5'-cyclic-AMP phosphodiesterase activity
def: "Reduction in extent, amount, or degree of 3',5'-cyclic-AMP phosphodiesterase activity." [DDB:pf]
synonym: "decreased cAMP-specific phosphodiesterase activity" EXACT []
is_a: DDPHENO:0001257 ! decreased catalytic activity

[Term]
id: DDPHENO:0001230
name: decreased 3',5'-cyclic-GMP phosphodiesterase activity
def: "Reduction in extent, amount, or degree of 3',5'-cyclic-GMP phosphodiesterase activity." [DDB:pf]
synonym: "decreased cGMP-specific phosphodiesterase activity" RELATED []
is_a: DDPHENO:0001257 ! decreased catalytic activity

[Term]
id: DDPHENO:0001231
name: abolished protein secretion
def: "Complete inability for protein secretion." [DDB:pf]
is_a: DDPHENO:0001030 ! aberrant protein secretion

[Term]
id: DDPHENO:0001232
name: increased protein secretion
def: "Increase in extent, amount, or degree of protein secretion." [DDB:pf]
is_a: DDPHENO:0001030 ! aberrant protein secretion
is_a: DDPHENO:0001337 ! increased protein localization

[Term]
id: DDPHENO:0001233
name: decreased protein secretion
def: "Reduction in extent, amount, or degree of protein secretion." [DDB:pf]
is_a: DDPHENO:0001030 ! aberrant protein secretion
is_a: DDPHENO:0001338 ! decreased protein localization

[Term]
id: DDPHENO:0001234
name: aberrant mitochondrion organization
def: "Deviation from the normal, usual, or expected events during mitochondrion organization." [DDB:pf]
synonym: "aberrant mitochondrion organization and biogenesis" RELATED []
is_a: DDPHENO:0001043 ! aberrant organelle organization

[Term]
id: DDPHENO:0001235
name: decreased ATP level
def: "Decrease in amount or accumulation of cytosolic ATP." [DDB:pf]
synonym: "decreased cytosolic ATP level" EXACT []
synonym: "decreased intracellular ATP" EXACT []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0001236
name: increased ATP level
def: "Increase in amount or accumulation of cytosolic ATP." [DDB:pf]
synonym: "increased cytosolic ATP level" EXACT []
synonym: "increased intracellular ATP level" EXACT []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0001237
name: aberrant lysosome organization
def: "Deviation from the normal, usual, or expected events during lysosome organization and biogenesis." [DDB:pf]
synonym: "aberrant lysosome maturation" NARROW []
synonym: "aberrant lysosome organization and biogenesis" EXACT []
is_a: DDPHENO:0001043 ! aberrant organelle organization

[Term]
id: DDPHENO:0001238
name: aberrant post-lysosomal vacuole exocytosis
def: "Deviation from the normal, usual, or expected events during post-lysosomal vacuole exocytosis." [DDB:pf]
synonym: "aberrant postlysosome exocytosis" EXACT []
is_a: DDPHENO:0001237 ! aberrant lysosome organization

[Term]
id: DDPHENO:0001239
name: abolished cell motility
def: "Complete inability for cell motility." [DDB:pg]
is_a: DDPHENO:0000264 ! aberrant cell motility

[Term]
id: DDPHENO:0001240
name: obsolete decreased CRAC localization to the plasma membrane
def: "OBSOLETE. Reduction in extent, amount or degree of CRAC localization to the plasma membrane." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001241
name: aberrant protein level
def: "Deviation from the normal, usual, or expected level of proteins." [DDB:pf]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001242
name: decreased protein level
def: "Reduction in extent, amount, or degree of protein expression." [DDB:pf]
is_a: DDPHENO:0001241 ! aberrant protein level

[Term]
id: DDPHENO:0001243
name: increased protein level
def: "Increase in extent, amount, or degree of protein expression." [DDB:pf]
is_a: DDPHENO:0001241 ! aberrant protein level

[Term]
id: DDPHENO:0001244
name: abolished protein level
def: "Complete elimination of protein expression." [DDB:pf]
is_a: DDPHENO:0001241 ! aberrant protein level

[Term]
id: DDPHENO:0001245
name: aberrant cAMP oscillatory signaling
def: "Deviation from the normal, usual, or expected events during cAMP signal oscillations during early development." [DDB:pf]
synonym: "aberrant cAMP relay" EXACT []
synonym: "aberrant cAMP-induced cAMP pulse" EXACT []
is_a: DDPHENO:0001038 ! aberrant extracellular cAMP signaling

[Term]
id: DDPHENO:0001246
name: abolished cAMP oscillatory signaling
def: "Complete inability for cAMP oscillatory signaling during early development." [DDB:pf]
synonym: "abolished cAMP relay" EXACT []
synonym: "abolished cAMP-induced cAMP pulse" EXACT []
is_a: DDPHENO:0001245 ! aberrant cAMP oscillatory signaling

[Term]
id: DDPHENO:0001247
name: aberrant protein methylation
def: "Deviation from the normal, usual, or expected events during protein methylation." [DDB:pf]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001248
name: abolished protein methylation
def: "Complete inability for protein methylation." [DDB:pf]
synonym: "abolished protein amino acid methylation" EXACT []
is_a: DDPHENO:0001247 ! aberrant protein methylation

[Term]
id: DDPHENO:0001249
name: abolished C-terminal protein methylation
def: "Complete inability for C-terminal protein methylation." [DDB:pf]
is_a: DDPHENO:0001248 ! abolished protein methylation

[Term]
id: DDPHENO:0001250
name: abolished establishment of cell polarity
def: "Complete inability to establish cell polarity." [DDB:pf]
synonym: "abolished cell polarity" EXACT []
is_a: DDPHENO:0001029 ! aberrant establishment or maintenance of cell polarity

[Term]
id: DDPHENO:0001251
name: obsolete increased protein kinase B activation
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true

[Term]
id: DDPHENO:0001252
name: obsolete abolished MAP kinase activation
def: "OBSOLETE. Complete inability for MAP activation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001253
name: obsolete decreased MAP kinase activation
def: "OBSOLETE. Reduction in extent, amount or degree of MAP kinase activation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001254
name: obsolete increased MAP kinase activation
def: "OBSOLETE. Increase in extent, amount, or degree of activation of a MAP kinase." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001255
name: aberrant binding
def: "Deviation from the normal, usual, or expected binding." [DDB:pg]
is_a: DDPHENO:0001171 ! aberrant molecular function

[Term]
id: DDPHENO:0001256
name: increased catalytic activity
def: "Increase in extent, amount, or degree of catalysis by an enzyme." [DDB:pg]
is_a: DDPHENO:0001105 ! aberrant catalytic activity

[Term]
id: DDPHENO:0001257
name: decreased catalytic activity
def: "A reduction in extent, amount, or degree of catalysis by an enzyme." [DDB:pg]
is_a: DDPHENO:0001105 ! aberrant catalytic activity

[Term]
id: DDPHENO:0001259
name: obsolete decreased binding
def: "OBSOLETE. Reduction in extent, amount or degree of molecule binding." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001260
name: increased cAMP binding
def: "Increased in extent, amount, or degree of binding to cAMP." [DDB:pg]
synonym: "increased 3',5'-cyclic-AMP binding" EXACT []
is_a: DDPHENO:0000324 ! aberrant cyclic nucleotide binding

[Term]
id: DDPHENO:0001261
name: decreased cAMP binding
def: "A reduction in extent, amount, or degree of binding to cAMP." [DDB:pg]
synonym: "decreased 3',5'-cyclic-AMP binding" EXACT []
is_a: DDPHENO:0000324 ! aberrant cyclic nucleotide binding
is_a: DDPHENO:0000329 ! decreased small molecule binding

[Term]
id: DDPHENO:0001262
name: aberrant adaptation of signaling pathway
def: "Deviation from the normal, usual, or expected events during the adaptation of a signaling pathway." [DDB:pg]
is_a: DDPHENO:0001118 ! aberrant signal transduction

[Term]
id: DDPHENO:0001263
name: aberrant autophagic cell death
def: "Deviation from the normal, usual, or expected events during autophagic cell death." [DDB:pf]
is_a: DDPHENO:0001267 ! aberrant cell death

[Term]
id: DDPHENO:0001264
name: abolished autophagic cell death
def: "Complete inability for autophagic cell death." [DDB:pf]
is_a: DDPHENO:0001263 ! aberrant autophagic cell death

[Term]
id: DDPHENO:0001265
name: increased autophagic cell death
def: "Increase in extent, amount, or degree of autophagic cell death." [DDB:pf]
is_a: DDPHENO:0001263 ! aberrant autophagic cell death

[Term]
id: DDPHENO:0001266
name: decreased autophagic cell death
def: "Reduction in extent, amount, or degree of autophagic cell death." [DDB:pf]
is_a: DDPHENO:0001263 ! aberrant autophagic cell death

[Term]
id: DDPHENO:0001267
name: aberrant cell death
def: "Deviation from the normal, usual, or expected events during regular cell death." [DDB:pf]
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0001268
name: obsolete aberrant non-apoptotic programmed cell death
def: "OBSOLETE. Deviation from the normal, usual, or expected events during non-apoptotic programmed cell death." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001269
name: obsolete abolished non-apoptotic programmed cell death
def: "OBSOLETE. Complete inability for non-apoptotic programmed cell death." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001270
name: obsolete increased non-apoptotic programmed cell death
def: "OBSOLETE. Increase in extent, amount, or degree of non-apoptotic programmed cell death." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001271
name: obsolete decreased non-apoptotic programmed cell death
def: "OBSOLETE. Reduction in extent, amount or degree of non-apoptotic programmed cell death." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001272
name: decreased pseudopodium retraction
def: "Reduction in extent, amount, or degree of pseudopodium retraction." [DDB:pf]
is_a: DDPHENO:0001027 ! aberrant pseudopodium formation

[Term]
id: DDPHENO:0001273
name: decreased uropod retraction
def: "Reduction in extent, amount, or degree of uropod retraction." [DDB:pf]
is_a: DDPHENO:0001048 ! aberrant cell projection biogenesis

[Term]
id: DDPHENO:0001274
name: abolished phagocytosis
def: "Complete inability for phagocytosis." [DDB:pf]
is_a: DDPHENO:0001006 ! aberrant phagocytosis

[Term]
id: DDPHENO:0001275
name: aberrant engulfment during phagocytosis
def: "Deviation from the normal, usual, or expected events during engulfment of attached, recognized, external material." [DDB:pf]
synonym: "aberrant phagocytosis, engulfment" EXACT []
synonym: "aberrant phagosome formation" RELATED []
is_a: DDPHENO:0001006 ! aberrant phagocytosis

[Term]
id: DDPHENO:0001276
name: abolished engulfment during phagocytosis
def: "Complete inability of engulfment of attached, recognized, external material." [DDB:pf]
synonym: "abolished phagocytosis, engulfment" EXACT []
synonym: "abolished phagosome formation" RELATED []
is_a: DDPHENO:0001275 ! aberrant engulfment during phagocytosis

[Term]
id: DDPHENO:0001277
name: decreased engulfment during phagocytosis
def: "Reduction in extent, amount, or degree of engulfment of attached, recognized, external material." [DDB:pf]
synonym: "decreased phagocytosis, engulfment" EXACT []
synonym: "decreased phagosome formation" RELATED []
is_a: DDPHENO:0001275 ! aberrant engulfment during phagocytosis

[Term]
id: DDPHENO:0001278
name: obsolete aberrant vacuolation
def: "OBSOLETE. Deviation from the normal, usual, or expected events during vacuolation." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001279
name: decreased autophagic vacuole organization
def: "Reduction in extent, amount, or degree of autophagic vacuole formation." [DDB:pf]
synonym: "decreased autophagic vacuole formation" EXACT []
is_a: DDPHENO:0001041 ! aberrant vacuole organization

[Term]
id: DDPHENO:0001280
name: increased 3',5'-cyclic-AMP phosphodiesterase activity
def: "Increase in extent, amount, or degree of 3',5'-cyclic-AMP phosphodiesterase activity." [DDB:pg]
synonym: "increased cAMP-specific phosphodiesterase activity" EXACT []
is_a: DDPHENO:0001256 ! increased catalytic activity

[Term]
id: DDPHENO:0001281
name: increased 3',5'-cyclic-GMP phosphodiesterase activity
def: "Increase in extent, amount, or degree of 3',5'-cyclic-GMP phosphodiesterase activity." [DDB:pg]
synonym: "increased cGMP-specific phosphodiesterase activity>" RELATED []
is_a: DDPHENO:0001256 ! increased catalytic activity

[Term]
id: DDPHENO:0001282
name: increased adenylate cyclase activity
def: "Increase in extent, amount, or degree of adenylate cyclase activity." [DDB:pg]
synonym: "increased ACA activity" EXACT []
is_a: DDPHENO:0001256 ! increased catalytic activity

[Term]
id: DDPHENO:0001283
name: obsolete decreased protein kinase A activity
def: "OBSOLETE. Reduction in extent, amount ordegree of protein kinase A activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001284
name: decreased guanyl-nucleotide exchange factor activity
def: "Reduction in extent, amount, or degree of guanyl-nucleotide exchange factor activity." [DDB:pf]
synonym: "decreased Ras activity" EXACT []
is_a: DDPHENO:0001257 ! decreased catalytic activity

[Term]
id: DDPHENO:0001285
name: decreased adenylate cyclase activity
def: "Reduction in extent, amount, or degree of adenylate cyclase activity." [DDB:pg]
synonym: "decreased ACA activity" EXACT []
is_a: DDPHENO:0001257 ! decreased catalytic activity

[Term]
id: DDPHENO:0001286
name: obsolete increased glycogen synthase kinase 3 activity
def: "OBSOLETE. Increase in extent, amount, or degree of glycogen synthase kinase 3 activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001287
name: increased guanylyl cyclase activity
def: "Increase in extent, amount, or degree of guanylyl cyclase activity." [DDB:pg]
synonym: "increased GC activity" EXACT []
synonym: "increased guanylate cyclase activity" EXACT []
is_a: DDPHENO:0001256 ! increased catalytic activity

[Term]
id: DDPHENO:0001288
name: decreased guanylyl cyclase activity
def: "Reduction in extent, amount, or degree of guanylyl cyclase activity." [DDB:pg]
synonym: "decreased GC activity" EXACT []
synonym: "decreased guanylate cyclase activity" EXACT []
is_a: DDPHENO:0001257 ! decreased catalytic activity

[Term]
id: DDPHENO:0001289
name: abolished catalytic activity
def: "Complete absence of catalytic activity." [DDB:pg]
is_a: DDPHENO:0001105 ! aberrant catalytic activity

[Term]
id: DDPHENO:0001290
name: abolished 3',5'-cyclic-AMP phosphodiesterase activity
def: "Complete absence of 3',5'-cyclic-AMP phosphodiesterase activity." [DDB:pg]
is_a: DDPHENO:0001289 ! abolished catalytic activity

[Term]
id: DDPHENO:0001291
name: abolished 3',5'-cyclic-GMP phosphodiesterase activity
def: "Complete absence of 3',5'-cyclic-GMP phosphodiesterase activity." [DDB:pg]
is_a: DDPHENO:0001289 ! abolished catalytic activity

[Term]
id: DDPHENO:0001292
name: obsolete abolished actin-dependent ATPase activity
def: "OBSOLETE. Complete absence of actin-dependent ATPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001293
name: abolished adenylate cyclase activity
def: "Complete absence of adenylate cyclase activity." [DDB:pg]
synonym: "abolished ACA activity" EXACT []
is_a: DDPHENO:0001289 ! abolished catalytic activity

[Term]
id: DDPHENO:0001294
name: obsolete abolished glycogen synthase kinase 3 activity
def: "OBSOLETE. Complete inability for glycogen synthase kinase 3 activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001295
name: abolished guanylyl cyclase activity
def: "Complete absence of guanylyl cyclase activity." [DDB:pg]
synonym: "abolished GC activity" EXACT []
is_a: DDPHENO:0001289 ! abolished catalytic activity

[Term]
id: DDPHENO:0001296
name: obsolete abolished GTP-gamma-S-stimulated guanylyl cyclase activity
def: "OBSOLETE. Complete inability for GTP-gamma-S-stimulated guanylyl cyclase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001297
name: abolished lysosomal protein degradation
def: "Complete absence of lysosomal protein degradation." [DDB:pf]
synonym: "abolished lysosomal protein catabolic process" RELATED []
synonym: "abolished lysosomal enzyme activity" RELATED []
is_a: DDPHENO:0001289 ! abolished catalytic activity

[Term]
id: DDPHENO:0001298
name: obsolete abolished protein kinase A activity
def: "OBSOLETE. Complete inability for protein kinase A activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001299
name: abolished guanyl-nucleotide exchange factor activity
def: "Complete absence of guanyl-nucleotide exchange factor activity." [DDB:pf]
synonym: "abolished GEF activity" EXACT []
is_a: DDPHENO:0001289 ! abolished catalytic activity

[Term]
id: DDPHENO:0001300
name: obsolete abolished protein kinase B activity
def: "OBSOLETE. Complete inability for protein kinase B activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001301
name: obsolete decreased protein kinase B activity
def: "OBSOLETE. Reduction in extent, amount ordegree of protein kinase B activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001302
name: obsolete increased protein kinase B activity
def: "OBSOLETE. Increase in extent, amount, or degree of protein kinase B activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001303
name: aberrant regulation of catalytic activity
def: "Deviation from the normal, usual, or expected events during the regulation of a catalytic activity." [DDB:pg]
is_a: DDPHENO:0001105 ! aberrant catalytic activity
is_a: DDPHENO:0001118 ! aberrant signal transduction

[Term]
id: DDPHENO:0001304
name: aberrant regulation of adenylate cyclase activity
def: "Deviation from the normal, usual, or expected events during the regulation of the activity of adenylate cyclase." [DDB:pg]
is_a: DDPHENO:0001303 ! aberrant regulation of catalytic activity

[Term]
id: DDPHENO:0001305
name: abolished cGMP-mediated signaling
def: "Complete inability for cGMP signaling." [DDB:pf]
synonym: "abolished cAMP induced cGMP pulse" RELATED []
synonym: "abolished cyclic GMP-mediated signaling" EXACT []
is_a: DDPHENO:0000694 ! aberrant cGMP-mediated signaling

[Term]
id: DDPHENO:0001306
name: obsolete abolished cAMP-induced cAMP pulse
def: "OBSOLETE. Complete inability to produce a cAMP pulse upon cAMP stimulation." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001307
name: obsolete abolished activation of Rab GTPase activity
def: "OBSOLETE. Complete inability for activation of of Rab GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001308
name: obsolete abolished activation of Rac GTPase activity
def: "OBSOLETE. Complete inability for activation of of Rac GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001309
name: obsolete abolished activation of Ran GTPase activity
def: "OBSOLETE. Complete inability for activation of of Ran GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001310
name: obsolete abolished activation of Rap GTPase activity
def: "OBSOLETE. Complete inability for activation of of Rap GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001311
name: aberrant activation of GTPase activity
def: "Deviation from the normal, usual, or expected events during the activation of the activity of a GTPase." [DDB:pg]
is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity

[Term]
id: DDPHENO:0001312
name: obsolete abolished activation of Ras GTPase activity
def: "OBSOLETE. Complete inability for activation of of Ras GTPase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001313
name: obsolete aberrant peptidyl-proline 4-dioxygenase activity
def: "OBSOLETE. Deviation from the normal, usual, or expected events during peptidyl-proline 4-dioxygenase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001314
name: obsolete decreased peptidyl-proline 4-dioxygenase activity
def: "OBSOLETE. Reduction in extent, amount or degree of peptidyl-proline 4-dioxygenase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001315
name: obsolete increased peptidyl-proline 4-dioxygenase activity
def: "OBSOLETE Increase in extent, amount, or degree of peptidyl-proline 4-dioxygenase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001316
name: obsolete abolished peptidyl-proline 4-dioxygenase activity
def: "OBSOLETE. Complete inability for peptidyl-proline 4-dioxygenase activity." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001317
name: aberrant protein modification
def: "Deviation from the normal, usual, or expected during protein modification." [DDB:pg]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process

[Term]
id: DDPHENO:0001318
name: aberrant peptidyl-proline modification
def: "Deviation from the normal, usual, or expected during peptidyl-proline modification." [DDB:pg]
is_a: DDPHENO:0001317 ! aberrant protein modification

[Term]
id: DDPHENO:0001319
name: increased peptidyl-proline modification
def: "Increase in level of modification of proline residues on a peptide." [DDB:pg]
is_a: DDPHENO:0001318 ! aberrant peptidyl-proline modification
is_a: DDPHENO:0001326 ! increased protein modification

[Term]
id: DDPHENO:0001320
name: decreased peptidyl-proline modification
def: "Reduction in level of modification of proline residues on a peptide." [DDB:pg]
is_a: DDPHENO:0001318 ! aberrant peptidyl-proline modification
is_a: DDPHENO:0001327 ! decreased protein modification

[Term]
id: DDPHENO:0001321
name: aberrant peptidyl-proline hydroxylation
def: "Deviation from the normal, usual, or expected during peptidyl-proline hydroxylation." [DDB:pg]
is_a: DDPHENO:0001318 ! aberrant peptidyl-proline modification

[Term]
id: DDPHENO:0001322
name: abolished peptidyl-proline modification
def: "Complete inability for peptidyl-proline modification." [DDB:pg]
is_a: DDPHENO:0001318 ! aberrant peptidyl-proline modification
is_a: DDPHENO:0001328 ! abolished protein modification

[Term]
id: DDPHENO:0001323
name: increased peptidyl-proline hydroxylation
def: "Increase in level of hydroxylation of proline residues on a peptide." [DDB:pg]
is_a: DDPHENO:0001321 ! aberrant peptidyl-proline hydroxylation
is_a: DDPHENO:0001326 ! increased protein modification

[Term]
id: DDPHENO:0001324
name: decreased peptidyl-proline hydroxylation
def: "Reduction in level of hydroxylation of proline residues on a peptide." [DDB:pg]
is_a: DDPHENO:0001321 ! aberrant peptidyl-proline hydroxylation
is_a: DDPHENO:0001327 ! decreased protein modification

[Term]
id: DDPHENO:0001325
name: abolished peptidyl-proline hydroxylation
def: "Complete inability for peptidyl-proline hydroxylation." [DDB:pg]
is_a: DDPHENO:0001321 ! aberrant peptidyl-proline hydroxylation
is_a: DDPHENO:0001328 ! abolished protein modification

[Term]
id: DDPHENO:0001326
name: increased protein modification
def: "Increase in level of modification of a protein." [DDB:pg]
synonym: "increased protein modification process" EXACT []
is_a: DDPHENO:0001317 ! aberrant protein modification

[Term]
id: DDPHENO:0001327
name: decreased protein modification
def: "Reduction in level of modification of a protein." [DDB:pg]
synonym: "decreased protein modification process" EXACT []
is_a: DDPHENO:0001317 ! aberrant protein modification

[Term]
id: DDPHENO:0001328
name: abolished protein modification
def: "Complete inability for protein modification." [DDB:pg]
synonym: "abolished protein modification process" EXACT []
is_a: DDPHENO:0001317 ! aberrant protein modification

[Term]
id: DDPHENO:0001329
name: obsolete decreased extracellular cAMP level
def: "OBSOLETE. Reduction in extent, amount or accumulation of extracellular cAMP level." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001330
name: obsolete increased extracellular cAMP level
def: "OBSOLETE. Increase in extent, amount, or degree of cAMP level." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001331
name: aberrant catalase activity
def: "Deviation from the normal, usual, or expected activity catalase." [DDB:pg]
is_a: DDPHENO:0001105 ! aberrant catalytic activity

[Term]
id: DDPHENO:0001332
name: abolished catalase activity
def: "Complete absence of catalase activity." [DDB:pg]
is_a: DDPHENO:0001289 ! abolished catalytic activity

[Term]
id: DDPHENO:0001333
name: decreased catalase activity
def: "Reduction in extent, amount, or degree of catalase activity." [DDB:pg]
is_a: DDPHENO:0001257 ! decreased catalytic activity

[Term]
id: DDPHENO:0001334
name: increased catalase activity
def: "Increase in extent, amount, or degree of catalase activity." [DDB:pg]
is_a: DDPHENO:0001256 ! increased catalytic activity

[Term]
id: DDPHENO:0001335
name: aberrant protein localization to plasma membrane
alt_id: DDPHENO:0000087
def: "Deviation from the normal, usual, or expected events during localization of a protein from the cytoplasm to the plasma membrane." [DDB:pf]
synonym: "aberrant localization to plasma membrane" BROAD []
is_a: DDPHENO:0000672 ! aberrant protein localization to cell periphery

[Term]
id: DDPHENO:0001336
name: aberrant protein localization to nucleus
alt_id: DDPHENO:0000083
def: "Deviation from the normal, usual, or expected events during localization of a protein to the nucleus." [DDB:pg]
synonym: "aberrant localization to nucleus" BROAD []
synonym: "aberrant nuclear protein localization" EXACT []
is_a: DDPHENO:0000471 ! aberrant protein localization

[Term]
id: DDPHENO:0001337
name: increased protein localization
def: "Increase in amount or accumulation of a protein at a certain location." [DDB:pg]
comment: Use for the altered localization of a protein that is affected by the mutation of another gene product.
is_a: DDPHENO:0000471 ! aberrant protein localization

[Term]
id: DDPHENO:0001338
name: decreased protein localization
def: "Reduction in amount or accumulation of a protein at a certain location." [DDB:pg]
comment: Use for the altered localization of a protein that is affected by the mutation of another gene product.
is_a: DDPHENO:0000471 ! aberrant protein localization

[Term]
id: DDPHENO:0001339
name: abolished secretion of lysosomal enzymes
def: "Complete inability for secretion of lysosomal enzymes." [DDB:pf]
is_a: DDPHENO:0001231 ! abolished protein secretion

[Term]
id: DDPHENO:0001340
name: decreased protein localization to nucleus
alt_id: DDPHENO:0000086
def: "Reduction in amount or accumulation of a protein in the nucleus." [DDB:pg]
synonym: "decreased localization to nucleus" BROAD []
synonym: "decreased nuclear protein localization" EXACT []
is_a: DDPHENO:0001336 ! aberrant protein localization to nucleus
is_a: DDPHENO:0001338 ! decreased protein localization

[Term]
id: DDPHENO:0001341
name: increased protein localization to nucleus
alt_id: DDPHENO:0000085
def: "Increase in amount or accumulation of a protein in the nucleus." [DDB:pg]
synonym: "increased localization to nucleus" BROAD []
synonym: "increased nuclear protein localization" EXACT []
is_a: DDPHENO:0001336 ! aberrant protein localization to nucleus
is_a: DDPHENO:0001337 ! increased protein localization

[Term]
id: DDPHENO:0001342
name: aberrant protein phosphorylation
def: "Deviation from the normal, usual, or expected events during phosphorylation of a protein." [DDB:pg]
is_a: DDPHENO:0001317 ! aberrant protein modification

[Term]
id: DDPHENO:0001343
name: increased protein phosphorylation
def: "Increase in amount or accumulation of phosphorylation of a protein." [DDB:pg]
is_a: DDPHENO:0001342 ! aberrant protein phosphorylation

[Term]
id: DDPHENO:0001344
name: decreased protein phosphorylation
def: "Reduction in amount or accumulation of phosphorylation of a protein." [DDB:pg]
is_a: DDPHENO:0001342 ! aberrant protein phosphorylation

[Term]
id: DDPHENO:0001345
name: aberrant protein tyrosine phosphorylation
def: "Deviation from the normal, usual, or expected events during tyrosine phosphorylation of a protein." [DDB:pg]
synonym: "aberrant peptidyl-tyrosine phosphorylation" EXACT []
is_a: DDPHENO:0001342 ! aberrant protein phosphorylation

[Term]
id: DDPHENO:0001346
name: increased protein tyrosine phosphorylation
def: "Increase in amount or accumulation of tyrosine phosphorylation of a protein." [DDB:pg]
synonym: "increased peptidyl-tyrosine phosphorylation" EXACT []
is_a: DDPHENO:0001343 ! increased protein phosphorylation
is_a: DDPHENO:0001345 ! aberrant protein tyrosine phosphorylation

[Term]
id: DDPHENO:0001347
name: decreased protein theronine phosphorylation
def: "Reduction in amount or accumulation of threonine phosphorylation of a protein." [DDB:pg]
synonym: "decreased peptidyl-threonine phosphorylation" EXACT []
is_a: DDPHENO:0001344 ! decreased protein phosphorylation
is_a: DDPHENO:0001345 ! aberrant protein tyrosine phosphorylation
is_a: DDPHENO:0001349 ! aberrant protein threonine phosphorylation

[Term]
id: DDPHENO:0001348
name: aberrant protein serine phosphorylation
def: "Deviation from the normal, usual, or expected events during serine phosphorylation of a protein." [DDB:pg]
synonym: "aberrant peptidyl-serine phosphorylation" EXACT []
is_a: DDPHENO:0001342 ! aberrant protein phosphorylation

[Term]
id: DDPHENO:0001349
name: aberrant protein threonine phosphorylation
def: "Deviation from the normal, usual, or expected events during threonine phosphorylation of a protein." [DDB:pg]
synonym: "aberrant peptidyl-threonine phosphorylation" EXACT []
is_a: DDPHENO:0001342 ! aberrant protein phosphorylation

[Term]
id: DDPHENO:0001350
name: decreased protein serine phosphorylation
def: "Reduction in amount or accumulation of serine phosphorylation of a protein." [DDB:pg]
synonym: "decreased peptidyl-serine phosphorylation" EXACT []
is_a: DDPHENO:0001344 ! decreased protein phosphorylation
is_a: DDPHENO:0001348 ! aberrant protein serine phosphorylation

[Term]
id: DDPHENO:0001351
name: increased protein serine phosphorylation
def: "Increase in amount or accumulation of serine phosphorylation of a protein." [DDB:pg]
synonym: "increased peptidyl-serine phosphorylation" EXACT []
is_a: DDPHENO:0001343 ! increased protein phosphorylation
is_a: DDPHENO:0001348 ! aberrant protein serine phosphorylation

[Term]
id: DDPHENO:0001352
name: decreased protein tyrosine phosphorylation
def: "Reduction in amount or accumulation of tyrosine phosphorylation of a protein." [DDB:pf]
is_a: DDPHENO:0001344 ! decreased protein phosphorylation

[Term]
id: DDPHENO:0001353
name: increased protein threonine phosphorylation
def: "Increase in amount or accumulation of threonine phosphorylation of a protein." [DDB:pg]
synonym: "increased peptidyl-threonine phosphorylation" EXACT []
is_a: DDPHENO:0001343 ! increased protein phosphorylation
is_a: DDPHENO:0001349 ! aberrant protein threonine phosphorylation

[Term]
id: DDPHENO:0001354
name: aberrant basal disc formation
def: "Deviation from the normal, usual, or expected during the formation of the basal disc." [DDB:pg]
is_a: DDPHENO:0000009 ! aberrant fruiting body morphology

[Term]
id: DDPHENO:0001355
name: decreased basal disc size
def: "Reduction in relative or proportionate dimensions of the basal disc." [DDB:pg]
is_a: DDPHENO:0001354 ! aberrant basal disc formation

[Term]
id: DDPHENO:0001356
name: abolished basal disc formation
def: "Complete absence of the basal disc." [DDB:pg]
is_a: DDPHENO:0001354 ! aberrant basal disc formation

[Term]
id: DDPHENO:0001357
name: aberrant outer basal disc formation
def: "Deviation from the normal, usual, or expected during the formation of the outer basal disc." [DDB:pg]
is_a: DDPHENO:0001354 ! aberrant basal disc formation

[Term]
id: DDPHENO:0001358
name: aberrant inner basal disc formation
def: "Deviation from the normal, usual, or expected during the formation of the inner basal disc." [DDB:pg]
is_a: DDPHENO:0001354 ! aberrant basal disc formation

[Term]
id: DDPHENO:0001359
name: abolished outer basal disc formation
def: "Complete absence of the outer basal disc." [DDB:pg]
is_a: DDPHENO:0001356 ! abolished basal disc formation
is_a: DDPHENO:0001357 ! aberrant outer basal disc formation

[Term]
id: DDPHENO:0001360
name: abolished inner basal disc formation
def: "Complete absence of the inner basal disc." [DDB:pg]
is_a: DDPHENO:0001356 ! abolished basal disc formation
is_a: DDPHENO:0001358 ! aberrant inner basal disc formation

[Term]
id: DDPHENO:0001361
name: decreased inner basal disc size
def: "Reduction in relative or proportionate dimensions of the inner basal disc." [DDB:pg]
is_a: DDPHENO:0001355 ! decreased basal disc size

[Term]
id: DDPHENO:0001362
name: decreased outer basal disc size
def: "Reduction in relative or proportionate dimensions of the outer basal disc." [DDB:pg]
is_a: DDPHENO:0001355 ! decreased basal disc size

[Term]
id: DDPHENO:0001363
name: increased inner basal disc size
def: "Increase in relative or proportionate dimensions of the inner basal disc." [DDB:pg]
is_a: DDPHENO:0000269 ! increased basal disc size

[Term]
id: DDPHENO:0001364
name: increased outer basal disc size
def: "Increase in relative or proportionate dimensions of the outer basal disc." [DDB:pg]
is_a: DDPHENO:0000269 ! increased basal disc size

[Term]
id: DDPHENO:0001365
name: aberrant lower cup formation
def: "Deviation from the normal, usual, or expected morphology of the lower cup." [DDB:pg]
is_a: DDPHENO:0000384 ! aberrant sorus morphology

[Term]
id: DDPHENO:0001366
name: aberrant upper cup formation
def: "Deviation from the normal, usual, or expected morphology of the upper cup." [DDB:pg]
is_a: DDPHENO:0000384 ! aberrant sorus morphology

[Term]
id: DDPHENO:0001367
name: abolished lower cup formation
def: "Complete inability to form a lower cup." [DDB:pg]
is_a: DDPHENO:0001365 ! aberrant lower cup formation

[Term]
id: DDPHENO:0001368
name: abolished upper cup formation
def: "Complete inability to form an upper cup." [DDB:pg]
is_a: DDPHENO:0001366 ! aberrant upper cup formation

[Term]
id: DDPHENO:0001369
name: increased lower cup size
def: "Increase in relative or proportionate dimensions of the lower cup." [DDB:pg]
is_a: DDPHENO:0001365 ! aberrant lower cup formation

[Term]
id: DDPHENO:0001370
name: decreased lower cup size
def: "Reduction in relative or proportionate dimensions of the lower cup." [DDB:pg]
is_a: DDPHENO:0001365 ! aberrant lower cup formation

[Term]
id: DDPHENO:0001371
name: increased upper cup size
def: "Increase in relative or proportionate dimensions of the upper cup." [DDB:pg]
is_a: DDPHENO:0001366 ! aberrant upper cup formation

[Term]
id: DDPHENO:0001372
name: decreased upper cup size
def: "Reduction in relative or proportionate dimensions of the upper cup." [DDB:pg]
is_a: DDPHENO:0001366 ! aberrant upper cup formation

[Term]
id: DDPHENO:0001373
name: decreased chemotaxis to arachidonic acid
def: "Reduction in extent, amount, or degree of chemotaxis in response to arachidonic acid." [DDB:pf]
is_a: DDPHENO:0000099 ! decreased chemotaxis rate

[Term]
id: DDPHENO:0001374
name: increased chemotaxis to arachidonic acid
def: "Increase in extent, amount, or degree of chemotaxis in response to arachidonic acid." [DDB:pf]
is_a: DDPHENO:0000400 ! increased chemotaxis rate

[Term]
id: DDPHENO:0001375
name: aberrant cellular homeostasis
def: "Deviation from the normal, usual, or expected events during cellular homeostasis." [DDB:pg]
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001376
name: increased glycogen level
def: "Increase in amount or accumulation of intracellular glycogen." [DDB:pg]
synonym: "increased cytosolic glycogen level" EXACT []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0001377
name: increased intracellular pH
def: "Increase in the pH in the cell." [DDB:pf]
synonym: "elevation of cellular pH," EXACT []
synonym: "increased cytosolic pH level" EXACT []
synonym: "intracellular pH elevation" EXACT []
is_a: DDPHENO:0001455 ! aberrant regulation of intracellular pH

[Term]
id: DDPHENO:0001378
name: decreased ammonia level
alt_id: DDPHENO:0001379
def: "Reduction in amount or accumulation of ammonia." [DDB:pf]
synonym: "decreased cytosolic ammonia level" NARROW []
synonym: "decreased extracellular ammonia level" NARROW []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis

[Term]
id: DDPHENO:0001381
name: obsolete decreased extracellular glucose level
def: "OBSOLETE. Reduction in extent, amount or accumulation of extracellular glucose." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001382
name: obsolete increased extracellular glucose level
def: "OBSOLETE. Increase in amount or accumulation of extracellular glucose." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001383
name: obsolete decreased extracellular pteridine level
def: "OBSOLETE. Reduction in extent, amount, or accumulation of extracellular pteridine level." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001384
name: decreased cytochrome C oxidase activity
def: "Reduction in extent, amount, or degree of cytochrome C oxidase activity." [DDB:pg]
synonym: "decreased COX activity" EXACT []
is_a: DDPHENO:0001257 ! decreased catalytic activity

[Term]
id: DDPHENO:0001385
name: increased cytochrome C oxidase activity
def: "Increase in extent, amount, or degree of cytochrome C oxidase activity." [DDB:pg]
synonym: "increased COX activity" EXACT []
is_a: DDPHENO:0001256 ! increased catalytic activity

[Term]
id: DDPHENO:0001386
name: abolished cytochrome C oxidase activity
def: "Complete absence of cytochrome C oxidase activity." [DDB:pg]
is_a: DDPHENO:0001289 ! abolished catalytic activity

[Term]
id: DDPHENO:0001387
name: obsolete aberrant CRAC localization to the plasma membrane
def: "OBSOLETE. Deviation from the normal, usual, or expected events during CRAC localization to the plasma membrane." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001388
name: obsolete increased CRAC localization to the plasma membrane
def: "OBSOLETE. Increase in extent, amount, or degree of CRAC localization to the plasma membrane." [DDB:pg]
is_obsolete: true

[Term]
id: DDPHENO:0001389
name: aberrant protein localization to cytoplasm
alt_id: DDPHENO:0000066
def: "Deviation from the normal, usual, or expected events during localization of a protein to the cytoplasm." [DDB:pg]
synonym: "aberrant localization to cytoplasm" BROAD []
is_a: DDPHENO:0000471 ! aberrant protein localization

[Term]
id: DDPHENO:0001390
name: increased protein localization to cytoplasm
alt_id: DDPHENO:0000068
def: "Increase in amount or accumulation of a protein in the cytoplasm." [DDB:pg]
synonym: "increased localization to cytoplasm" BROAD []
is_a: DDPHENO:0001337 ! increased protein localization
is_a: DDPHENO:0001389 ! aberrant protein localization to cytoplasm

[Term]
id: DDPHENO:0001391
name: decreased protein localization to cytoplasm
alt_id: DDPHENO:0000069
def: "Reduction in amount or accumulation of a protein in the cytoplasm." [DDB:pg]
synonym: "decreased localization to cytoplasm" BROAD []
is_a: DDPHENO:0001338 ! decreased protein localization
is_a: DDPHENO:0001389 ! aberrant protein localization to cytoplasm

[Term]
id: DDPHENO:0001392
name: abolished protein localization to cytoplasm
alt_id: DDPHENO:0000067
def: "Complete inability to localize a protein to the cytoplasm." [DDB:pf, DDB:pg]
synonym: "abolished localization to cytoplasm" BROAD []
is_a: DDPHENO:0001389 ! aberrant protein localization to cytoplasm
is_a: DDPHENO:0001393 ! abolished protein localization

[Term]
id: DDPHENO:0001393
name: abolished protein localization
def: "Complete inability to localize a protein to a cellular compartment or structure." [DDB:pf, DDB:pg]
comment: Use for the abolished localization of a protein that is affected by the mutation of another gene product.
is_a: DDPHENO:0000471 ! aberrant protein localization

[Term]
id: DDPHENO:0001394
name: abolished protein localization to plasma membrane
alt_id: DDPHENO:0000088
def: "Complete inability to localize a protein to the plasma membrane." [DDB:pf, DDB:pg]
synonym: "abolished localization to plasma membrane" BROAD []
is_a: DDPHENO:0000673 ! abolished protein localization to cell periphery
is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane

[Term]
id: DDPHENO:0001395
name: decreased protein localization to plasma membrane
alt_id: DDPHENO:0000089
def: "Reduction in the ability for localization of a protein from the cytoplasm to the plasma." [DDB:pf, DDB:pg]
synonym: "decreased localization to plasma membrane" BROAD []
is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane
is_a: DDPHENO:0001338 ! decreased protein localization

[Term]
id: DDPHENO:0001396
name: increased protein localization to plasma membrane
alt_id: DDPHENO:0000091
def: "Increase in the ability for localization of a protein from the cytoplasm to the plasma membrane." [DDB:pf, DDB:pg]
synonym: "increased localization to plasma membrane" BROAD []
is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane
is_a: DDPHENO:0001337 ! increased protein localization

[Term]
id: DDPHENO:0001397
name: increased cAMP oscillatory signaling
def: "Extended duration for cAMP oscillatory signaling during early development." [DDB:pf]
synonym: "increased cAMP relay" EXACT []
synonym: "increased cAMP-induced cAMP pulse" EXACT []
is_a: DDPHENO:0001245 ! aberrant cAMP oscillatory signaling

[Term]
id: DDPHENO:0001398
name: decreased cAMP oscillatory signaling
def: "Shortened duration for cAMP oscillatory signaling during early development." [DDB:pf]
synonym: "decreased cAMP-induced cAMP pulse" EXACT []
synonym: "shortened cAMP relay" EXACT []
is_a: DDPHENO:0001245 ! aberrant cAMP oscillatory signaling

[Term]
id: DDPHENO:0001399
name: abolished protein localization to microtubules
alt_id: DDPHENO:0000075
def: "Complete inability to localize a protein to the to microtubules." [DDB:pf]
synonym: "abolished localization to microtubules" BROAD []
is_a: DDPHENO:0001393 ! abolished protein localization
is_a: DDPHENO:0001514 ! aberrant protein localization to microtubules

[Term]
id: DDPHENO:0001400
name: abolished protein localization to microtubule organizing center
alt_id: DDPHENO:0000071
def: "Complete inability to localize a protein to the microtubule organizing center." [DDB:pf]
synonym: "abolished localization to microtubule organizing center" BROAD []
synonym: "abolished protein localization to the MTOC" EXACT []
is_a: DDPHENO:0001393 ! abolished protein localization
is_a: DDPHENO:0001513 ! aberrant protein localization to microtubule organizing center

[Term]
id: DDPHENO:0001401
name: decreased protein localization to microtubule organizing center
alt_id: DDPHENO:0000073
def: "Reduction in amount or accumulation of a protein to the microtubule organizing center." [DDB:pf]
synonym: "decreased localization to microtubule organizing center" BROAD []
synonym: "decreased protein localization to the MTOC" EXACT []
is_a: DDPHENO:0001338 ! decreased protein localization
is_a: DDPHENO:0001513 ! aberrant protein localization to microtubule organizing center

[Term]
id: DDPHENO:0001402
name: decreased protein localization to microtubules
alt_id: DDPHENO:0000076
def: "Reduction in amount or accumulation of a protein at the microtubules." [DDB:pf]
synonym: "decreased localization to microtubules" BROAD []
is_a: DDPHENO:0001338 ! decreased protein localization
is_a: DDPHENO:0001514 ! aberrant protein localization to microtubules

[Term]
id: DDPHENO:0001403
name: increased protein localization to microtubules
alt_id: DDPHENO:0000078
def: "Increase in amount or accumulation of a protein at the microtubules." [DDB:pf]
synonym: "increased localization to microtubules" BROAD []
is_a: DDPHENO:0001337 ! increased protein localization
is_a: DDPHENO:0001514 ! aberrant protein localization to microtubules

[Term]
id: DDPHENO:0001404
name: increased protein localization to microtubule organizing center
alt_id: DDPHENO:0000072
def: "Increase in amount or accumulation of a protein to the microtubule organizing center." [DDB:pf]
synonym: "increased localization to microtubule organizing center" BROAD []
synonym: "increased protein localization to the MTOC" EXACT []
is_a: DDPHENO:0001337 ! increased protein localization
is_a: DDPHENO:0001513 ! aberrant protein localization to microtubule organizing center

[Term]
id: DDPHENO:0001405
name: abolished protein localization to coated pits
alt_id: DDPHENO:0000063
def: "Complete inability to localize a protein to coated pits." [DDB:pf]
synonym: "abolished localization to coated pits" BROAD []
synonym: "abolished protein localization of protein to clathrin-coated pits" EXACT []
is_a: DDPHENO:0001393 ! abolished protein localization
is_a: DDPHENO:0001408 ! aberrant protein localization to coated pits

[Term]
id: DDPHENO:0001406
name: decreased protein localization to coated pits
alt_id: DDPHENO:0000065
def: "Reduction in amount or accumulation of a protein to coated pits." [DDB:pf]
synonym: "decreased localization to coated pits" BROAD []
synonym: "decreased protein localization of protein to clathrin-coated pits" EXACT []
is_a: DDPHENO:0001338 ! decreased protein localization
is_a: DDPHENO:0001408 ! aberrant protein localization to coated pits

[Term]
id: DDPHENO:0001407
name: increased protein localization to coated pits
alt_id: DDPHENO:0000064
def: "Increase in amount or accumulation of a protein to coated pits." [DDB:pf]
synonym: "increased localization to coated pits" BROAD []
synonym: "increased protein localization of protein to clathrin-coated pits" EXACT []
is_a: DDPHENO:0001337 ! increased protein localization
is_a: DDPHENO:0001408 ! aberrant protein localization to coated pits

[Term]
id: DDPHENO:0001408
name: aberrant protein localization to coated pits
alt_id: DDPHENO:0000062
def: "Deviation from the normal, usual, or expected events during localization of a protein to coated pits." [DDB:pf]
synonym: "aberrant localization to coated pits" BROAD []
synonym: "aberrant protein localization of a protein to clathrin-coated pits" EXACT []
is_a: DDPHENO:0000471 ! aberrant protein localization

[Term]
id: DDPHENO:0001409
name: abolished phosphoinositide binding
def: "Complete absence of phosphoinositide binding." [DDB:pf]
is_a: DDPHENO:0000326 ! abolished lipid binding

[Term]
id: DDPHENO:0001410
name: abolished phosphatidylinositol-4,5-bisphosphate binding
def: "Complete absence of phosphatidylinositol-4,5-bisphosphate binding." [DDB:pf]
is_a: DDPHENO:0001409 ! abolished phosphoinositide binding

[Term]
id: DDPHENO:0001411
name: obsolete aberrant response to conditioned medium factor
def: "OBSOLETE. Deviation from the normal, usual, or expected events during the response to conditioned medium factor (CMF) found in conditioned media (CM)." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001412
name: aberrant protein localization to pseudopodium
alt_id: DDPHENO:0000092
def: "Deviation from the normal, usual, or expected events during localization of a protein to pseudopodia." [DDB:pf]
synonym: "aberrant localization to pseudopodium" BROAD []
is_a: DDPHENO:0000471 ! aberrant protein localization

[Term]
id: DDPHENO:0001413
name: decreased protein localization to pseudopodium
alt_id: DDPHENO:0000095
def: "Reduction in amount or accumulation of a protein in pseudopodia." [DDB:pf]
synonym: "decreased localization to pseudopodium" BROAD []
is_a: DDPHENO:0001338 ! decreased protein localization
is_a: DDPHENO:0001412 ! aberrant protein localization to pseudopodium

[Term]
id: DDPHENO:0001414
name: increased protein localization to pseudopodium
alt_id: DDPHENO:0000096
def: "Increase in amount or accumulation of a protein in pseudopodia." [DDB:pf]
synonym: "increased localization to pseudopodium" BROAD []
is_a: DDPHENO:0001337 ! increased protein localization
is_a: DDPHENO:0001412 ! aberrant protein localization to pseudopodium

[Term]
id: DDPHENO:0001415
name: increased fruiting body size
def: "Increase in relative or proportionate dimensions of the fruiting body." [DDB:pf]
synonym: "increased sorocarp size" EXACT []
synonym: "large fruiting body" EXACT []
is_a: DDPHENO:0000009 ! aberrant fruiting body morphology

[Term]
id: DDPHENO:0001416
name: aberrant cell separation during cytokinesis
def: "Deviation from the normal, usual, or expected events during cell separation during cytokinesis." [DDB:pf]
is_a: DDPHENO:0000149 ! aberrant cytokinesis

[Term]
id: DDPHENO:0001417
name: delayed cell separation during cytokinesis
def: "Late onset or slower progression for cell separation during cytokinesis." [DDB:pf]
is_a: DDPHENO:0001169 ! delayed cytokinesis
is_a: DDPHENO:0001416 ! aberrant cell separation during cytokinesis

[Term]
id: DDPHENO:0001418
name: aberrant cell cycle
def: "Deviation from the normal, usual, or expected cell cycle event." [DDB:pf]
is_a: DDPHENO:0001008 ! aberrant cellular process

[Term]
id: DDPHENO:0001419
name: aberrant mitotic spindle organization
def: "Deviation from the normal, usual, or expected during mitotic spindle organization." [DDB:pf]
synonym: "mitotic spindle stabilization" RELATED []
is_a: DDPHENO:0001418 ! aberrant cell cycle

[Term]
id: DDPHENO:0001420
name: precocious mitotic spindle elongation
def: "Early onset or faster progression through mitotic spindle elongation." [DDB:pf]
is_a: DDPHENO:0001486 ! aberrant mitotic spindle elongation

[Term]
id: DDPHENO:0001421
name: obsolete decreased spindle stabilization
def: "OBSOLETE. Reduction in spindle stabilization." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001422
name: aberrant sister chromosome segregation
def: "Deviation from the normal, usual, or expected events during sister chromosome segregation, resulting in an abnormal number of chromosomes." [DDB:pf]
synonym: "aberrant mitotic sister chromatid segregation" EXACT []
synonym: "aneuploidy" RELATED []
is_a: DDPHENO:0001418 ! aberrant cell cycle

[Term]
id: DDPHENO:0001423
name: aberrant nuclear envelope morphology
def: "Deviation from the normal, usual, or expected morphology of the nuclear envelope." [DDB:pf]
is_a: DDPHENO:0000263 ! aberrant nucleus morphology

[Term]
id: DDPHENO:0001424
name: aberrant perinuclear space
def: "Deviation from the normal, usual, or expected morphology of the perinuclear space." [DDB:pf]
synonym: "aberrant nuclear membrane lumen" EXACT []
is_a: DDPHENO:0001423 ! aberrant nuclear envelope morphology

[Term]
id: DDPHENO:0001425
name: aberrant centrosome organization
def: "Deviation from the normal, usual, or expected events during centrosome organization." [DDB:pf]
is_a: DDPHENO:0001043 ! aberrant organelle organization

[Term]
id: DDPHENO:0001426
name: increased number of centrosomes
def: "Quantitative increase in centrosomes." [DDB:pf]
is_a: DDPHENO:0001425 ! aberrant centrosome organization

[Term]
id: DDPHENO:0001427
name: aberrant protein localization to nuclear envelope
alt_id: DDPHENO:0000079
def: "Deviation from the normal, usual, or expected events during localization of a protein to the nuclear envelope." [DDB:pf]
synonym: "aberrant localization to nuclear envelope" BROAD []
is_a: DDPHENO:0000471 ! aberrant protein localization

[Term]
id: DDPHENO:0001428
name: abolished protein localization to nuclear envelope
alt_id: DDPHENO:0000080
def: "Complete inability to localize a protein to the nuclear envelope." [DDB:pf]
synonym: "abolished localization to nuclear envelope" BROAD []
is_a: DDPHENO:0001393 ! abolished protein localization
is_a: DDPHENO:0001427 ! aberrant protein localization to nuclear envelope

[Term]
id: DDPHENO:0001429
name: decreased protein localization to nuclear envelope
alt_id: DDPHENO:0000082
def: "Reduction in amount or accumulation of a protein at the nuclear envelope." [DDB:pf]
synonym: "decreased localization to nuclear envelope" BROAD []
is_a: DDPHENO:0001338 ! decreased protein localization
is_a: DDPHENO:0001427 ! aberrant protein localization to nuclear envelope

[Term]
id: DDPHENO:0001430
name: increased protein localization to nuclear envelope
alt_id: DDPHENO:0000081
def: "Increase in amount or accumulation of a protein in the nuclear envelope." [DDB:pf]
synonym: "increased localization to nuclear envelope" BROAD []
is_a: DDPHENO:0001337 ! increased protein localization
is_a: DDPHENO:0001427 ! aberrant protein localization to nuclear envelope

[Term]
id: DDPHENO:0001431
name: aberrant development of tipped mound
def: "Deviation from the normal, usual, or expected events during development of tipped mound." [DDB:pf]
synonym: "aberrant sorocarp development of tipped mound" EXACT []
synonym: "aberrant tip formation" RELATED []
is_a: DDPHENO:0000154 ! aberrant sorocarp development

[Term]
id: DDPHENO:0001432
name: delayed sporulation
def: "Late onset or slower progression through spore formation." [DDB:pf]
is_a: DDPHENO:0000513 ! aberrant sporulation

[Term]
id: DDPHENO:0001433
name: aberrant GABA signaling pathway
def: "Deviation from the normal, usual, or expected events during the gamma-aminobutyric acid signaling pathway." [DDB:pf]
synonym: "aberrant gamma-aminobutyric acid signaling pathway" EXACT []
is_a: DDPHENO:0001118 ! aberrant signal transduction

[Term]
id: DDPHENO:0001434
name: abolished histone deacetylase activity
def: "Complete absence of histone deacetylase activity." [DDB:pg]
is_a: DDPHENO:0001289 ! abolished catalytic activity

[Term]
id: DDPHENO:0001435
name: decreased histone deacetylase activity
def: "Reduction in extent, amount, or degree of histone deacetylase activity." [DDB:pg]
is_a: DDPHENO:0001257 ! decreased catalytic activity

[Term]
id: DDPHENO:0001436
name: increased histone deacetylase activity
def: "Increase in extent, amount, or degree of histone deacetylase activity." [DDB:pg]
is_a: DDPHENO:0001256 ! increased catalytic activity

[Term]
id: DDPHENO:0001437
name: aberrant necrotic cell death
def: "Deviation from the normal, usual, or expected events during necrotic cell death." [DDB:pf]
is_a: DDPHENO:0001267 ! aberrant cell death

[Term]
id: DDPHENO:0001438
name: abolished necrotic cell death
def: "Complete inability for necrotic cell death." [DDB:pf]
is_a: DDPHENO:0001437 ! aberrant necrotic cell death

[Term]
id: DDPHENO:0001439
name: decreased necrotic cell death
def: "Reduction in extent, amount, or degree of necrotic cell death." [DDB:pf]
is_a: DDPHENO:0001437 ! aberrant necrotic cell death

[Term]
id: DDPHENO:0001440
name: increased necrotic cell death
def: "Increase in extent, amount, or degree of necrotic cell death." [DDB:pf]
is_a: DDPHENO:0001437 ! aberrant necrotic cell death

[Term]
id: DDPHENO:0001441
name: aberrant cell fate commitment
def: "Deviation from the normal, usual, or expected events when committing cells for a specific fate in their normal environment." [DDB:pf]
is_a: DDPHENO:0001013 ! aberrant cell differentiation

[Term]
id: DDPHENO:0001442
name: decreased cell fate commitment
def: "Reduction in extent, amount, or degree when committing cells for a specific fate in their normal environment." [DDB:pf]
is_a: DDPHENO:0001441 ! aberrant cell fate commitment

[Term]
id: DDPHENO:0001443
name: aberrant cell fate determination
def: "Deviation from the normal, usual, or expected events when determining cells for a specific fate regardless of its environment." [DDB:pf]
is_a: DDPHENO:0001441 ! aberrant cell fate commitment

[Term]
id: DDPHENO:0001444
name: decreased cell fate determination
def: "Reduction in extent, amount, or degree when determining cells for a specific fate regardless of its environment." [DDB:pf]
is_a: DDPHENO:0001443 ! aberrant cell fate determination

[Term]
id: DDPHENO:0001445
name: aberrant actin filament polymerization
def: "Deviation from the normal, usual, or expected events during F-actin polymerization." [DDB:pf]
synonym: "aberrant F-actin polymerization" EXACT []
is_a: DDPHENO:0000151 ! aberrant actin filament organization
created_by: pfey
creation_date: 2010-02-03T05:27:42Z

[Term]
id: DDPHENO:0001446
name: aberrant actin filament depolymerization
def: "Deviation from the normal, usual, or expected events during F-actin depolymerization." [DDB:pf]
synonym: "aberrant F-actin depolymerization" EXACT []
is_a: DDPHENO:0000151 ! aberrant actin filament organization
created_by: pfey
creation_date: 2010-02-03T05:54:09Z

[Term]
id: DDPHENO:0001447
name: abolished actin filament depolymerization
def: "Complete inability to depolymerize actin into F-actin." [DDB:pf]
synonym: "abolished F-actin depolymerization" EXACT []
is_a: DDPHENO:0001446 ! aberrant actin filament depolymerization
created_by: pfey
creation_date: 2010-02-03T05:57:47Z

[Term]
id: DDPHENO:0001448
name: decreased actin filament depolymerization
def: "Reduction in extent, amount, or degree of F-actin depolymerization." [DDB:pf]
synonym: "decreased F-actin depolymerization" EXACT []
is_a: DDPHENO:0001446 ! aberrant actin filament depolymerization
created_by: pfey
creation_date: 2010-02-03T05:59:24Z

[Term]
id: DDPHENO:0001449
name: increased actin filament depolymerization
def: "Increase in extent, amount, or degree of F-actin depolymerization." [DDB:pf]
synonym: "increased F-actin depolymerization" EXACT []
is_a: DDPHENO:0001446 ! aberrant actin filament depolymerization
created_by: pfey
creation_date: 2010-02-03T06:00:17Z

[Term]
id: DDPHENO:0001450
name: abolished protein phosphorylation
def: "Complete inability for protein phosphorylation." [DDB:pf]
is_a: DDPHENO:0001342 ! aberrant protein phosphorylation
created_by: pfey
creation_date: 2010-02-16T04:04:04Z

[Term]
id: DDPHENO:0001451
name: abolished phosphorylation of actin
def: "Complete inability for actin phosphorylation." [DDB:pf]
is_a: DDPHENO:0001450 ! abolished protein phosphorylation
created_by: pfey
creation_date: 2010-02-16T04:06:48Z

[Term]
id: DDPHENO:0001452
name: abolished protein serine phosphorylation
def: "Complete inability for protein serine phosphorylation." [DDB:pf]
is_a: DDPHENO:0001450 ! abolished protein phosphorylation
created_by: pfey
creation_date: 2010-02-16T04:07:35Z

[Term]
id: DDPHENO:0001453
name: abolished protein threonine phosphorylation
def: "Complete inability for protein threonine phosphorylation." [DDB:pf]
is_a: DDPHENO:0001450 ! abolished protein phosphorylation
created_by: pfey
creation_date: 2010-02-16T04:08:34Z

[Term]
id: DDPHENO:0001454
name: abolished protein tyrosine phosphorylation
def: "Complete inability for protein tyrosine phosphorylation." [DDB:pf]
is_a: DDPHENO:0001450 ! abolished protein phosphorylation
created_by: pfey
creation_date: 2010-02-16T04:08:50Z

[Term]
id: DDPHENO:0001455
name: aberrant regulation of intracellular pH
def: "Deviation from the normal, usual, or expected regulation of the intracellular pH." [DDB:pf]
synonym: "aberrant intracellular pH level" EXACT []
is_a: DDPHENO:0001375 ! aberrant cellular homeostasis
created_by: pfey
creation_date: 2010-02-19T11:12:47Z

[Term]
id: DDPHENO:0001456
name: aberrant response to cisplatin
def: "Deviation from the normal, usual, or expected events during the response to cisplatin." [DDb:pg]
is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus
created_by: Pascale
creation_date: 2010-03-10T09:58:37Z

[Term]
id: DDPHENO:0001457
name: obsolete aberrant DNA repair
def: "OBSOLETE. Deviation from the normal, usual, or expected events during DNA repair." [DDB:pg]
is_obsolete: true
created_by: Pascale
creation_date: 2010-03-10T10:44:05Z

[Term]
id: DDPHENO:0001458
name: obsolete aberrant double-strand break repair via homologous recombination
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true
created_by: Pascale
creation_date: 2010-03-10T10:44:20Z

[Term]
id: DDPHENO:0001459
name: obsolete decreased double-strand break repair via homologous recombination
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true
created_by: Pascale
creation_date: 2010-03-10T10:44:37Z

[Term]
id: DDPHENO:0001460
name: obsolete increased double-strand break repair via homologous recombination
def: "OBSOLETE. Was not defined before obsoletion." []
is_obsolete: true
created_by: Pascale
creation_date: 2010-03-10T10:44:51Z

[Term]
id: DDPHENO:0001461
name: obsolete aberrant chemotaxis to cAMP in response to DIF-1
def: "OBSOLETE. Deviation from the normal, usual, or expected events during chemotaxis to cAMP in response to DIF-1." [DDB:pg]
is_obsolete: true
created_by: Pascale
creation_date: 2010-03-15T04:04:23Z

[Term]
id: DDPHENO:0001462
name: obsolete aberrant chemotaxis to cAMP in response to DIF-2
def: "OBSOLETE. Deviation from the normal, usual, or expected events during chemotaxis to cAMP in response to DIF-2." [DDB:pg]
is_obsolete: true
created_by: Pascale
creation_date: 2010-03-15T04:05:48Z

[Term]
id: DDPHENO:0001463
name: aberrant regulation of positive chemotaxis
def: "Deviation from the normal, usual, or expected events during the regulation of the locomotory response." [DDB:pf]
is_a: DDPHENO:0001224 ! aberrant positive chemotaxis
created_by: Pascale
creation_date: 2010-03-15T04:20:58Z

[Term]
id: DDPHENO:0001464
name: obsolete aberrant regulation of chemotaxis to cAMP in response to DIF-1
def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of chemotaxis to cAMP in response to DIF-1." [DDB:pg]
is_obsolete: true
created_by: Pascale
creation_date: 2010-03-15T04:24:28Z

[Term]
id: DDPHENO:0001465
name: obsolete aberrant regulation of chemotaxis to cAMP in response to DIF-2
def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of chemotaxis to cAMP in response to DIF-2." [DDB:pg]
is_obsolete: true
created_by: Pascale
creation_date: 2010-03-15T04:25:54Z

[Term]
id: DDPHENO:0001466
name: aberrant microtubule nucleation
def: "Deviation from the normal, usual, or expected events during microtubule nucleation." [DDB:pf]
xref: DDB:pf
is_a: DDPHENO:0000413 ! aberrant microtubule cytoskeleton organization
created_by: pfey
creation_date: 2010-03-17T02:07:26Z

[Term]
id: DDPHENO:0001467
name: decreased microtubule nucleation
def: "Reduction in extent, amount, or degree of microtubule nucleation." [DDB:pf]
is_a: DDPHENO:0001466 ! aberrant microtubule nucleation
created_by: pfey
creation_date: 2010-03-17T02:16:06Z

[Term]
id: DDPHENO:0001468
name: increased microtubule nucleation
def: "Increase in amount or rate of microtubule nucleation." [DDB:pf]
is_a: DDPHENO:0001466 ! aberrant microtubule nucleation
created_by: pfey
creation_date: 2010-03-17T02:20:17Z

[Term]
id: DDPHENO:0001469
name: aberrant centromere complex assembly
def: "Deviation from the normal, usual, or expected events during centromere complex assembly." [DDB:pf]
is_a: DDPHENO:0001043 ! aberrant organelle organization
created_by: pfey
creation_date: 2010-03-19T03:00:52Z

[Term]
id: DDPHENO:0001470
name: decreased response to lithium
def: "Reduction in extent, amount, or degree of response to lithium." [DDB:pf]
is_a: DDPHENO:0001108 ! aberrant response to lithium
created_by: pfey
creation_date: 2010-09-06T12:50:53Z

[Term]
id: DDPHENO:0001471
name: increased response to lithium
def: "Increase in extent, amount, or degree of response to lithium." [DDB:pf]
is_a: DDPHENO:0001108 ! aberrant response to lithium
created_by: pfey
creation_date: 2010-09-06T12:54:23Z

[Term]
id: DDPHENO:0001472
name: aberrant inositol phosphate metabolic process
def: "Deviation from the normal, usual, or expected events during inositol phosphate metabolism." [DDB:pf]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2011-03-24T02:17:45Z

[Term]
id: DDPHENO:0001473
name: aberrant glucose catabolic process
def: "Deviation from the normal, usual, or expected events during glucose catabolism." [DDB:pf]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2011-03-24T02:22:00Z

[Term]
id: DDPHENO:0001474
name: obsolete increased intracellular 2,3-bisphosphoglycerate
def: "OBSOLETE. Increase in amount or accumulation of intracellular 2,3-bisphosphoglycerate." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2011-03-24T02:29:08Z

[Term]
id: DDPHENO:0001475
name: abolished histone H3-K79 methylation
def: "Complete inability for methylation of histone H3 at lysine 79." [DDB:pf]
is_a: DDPHENO:0001476 ! abolished histone lysine methylation
created_by: pfey
creation_date: 2011-09-13T10:47:22Z

[Term]
id: DDPHENO:0001476
name: abolished histone lysine methylation
def: "Complete inability for methylation of a lysine in histone H3." [DDB:pf]
is_a: DDPHENO:0001248 ! abolished protein methylation
created_by: pfey
creation_date: 2011-09-13T10:54:35Z

[Term]
id: DDPHENO:0001477
name: abolished histone H3-K9 methylation
def: "Complete inability for methylation of histone H3 at lysine 9." [DDB:pf]
is_a: DDPHENO:0001476 ! abolished histone lysine methylation
created_by: pfey
creation_date: 2011-09-13T10:57:06Z

[Term]
id: DDPHENO:0001478
name: abolished cell-cell adhesion
def: "Complete inability of cell-cell adhesion." [DDB:pf]
is_a: DDPHENO:0000412 ! aberrant cell-cell adhesion
created_by: pfey
creation_date: 2011-09-13T11:17:59Z

[Term]
id: DDPHENO:0001479
name: abolished calcium-dependent cell-cell adhesion
def: "Complete inability of calcium-dependent cell-cell adhesion." [DDB:pf]
synonym: "abolished calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT []
synonym: "abolished EDTA-sensitive cell-cell adhesion" RELATED []
is_a: DDPHENO:0001478 ! abolished cell-cell adhesion
created_by: pfey
creation_date: 2011-09-13T11:19:21Z

[Term]
id: DDPHENO:0001480
name: abolished calcium-independent cell-cell adhesion
def: "Complete inability of calcium-independent cell-cell adhesion." [DDB:pf]
synonym: "abolished calcium-independent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT []
synonym: "abolished EDTA-resistant cell adhesion" RELATED []
is_a: DDPHENO:0001478 ! abolished cell-cell adhesion
created_by: pfey
creation_date: 2011-09-13T11:21:46Z

[Term]
id: DDPHENO:0001481
name: aberrant actin cytoskeleton organization
def: "Deviation from the normal, usual, or expected events during organization of the actin cytoskeleton." [DDB:pf]
is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization

[Term]
id: DDPHENO:0001482
name: aberrant cortical actin cytoskeleton organization
def: "Deviation from the normal, usual, or expected events during organization of the cortical actin cytoskeleton." [DDB:pf]
synonym: "aberrant cortical actin cytoskeleton stabilization" RELATED []
is_a: DDPHENO:0001481 ! aberrant actin cytoskeleton organization

[Term]
id: DDPHENO:0001483
name: obsolete aberrant cortical actin cytoskeleton stabilization
def: "OBSOLETE. Deviation from the normal, usual, or expected events in the maintenance of the cortical actin cytoskeleton." [DDB:pf]
is_obsolete: true

[Term]
id: DDPHENO:0001484
name: obsolete aberrant spindle stabilization
def: "OBSOLETE. Deviation from the normal, usual, or expected during spindle stabilization." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2012-04-16T01:41:00Z

[Term]
id: DDPHENO:0001485
name: obsolete increased spindle stabilization
def: "OBSOLETE. Increase in spindle stabilization." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2012-04-16T01:51:35Z

[Term]
id: DDPHENO:0001486
name: aberrant mitotic spindle elongation
def: "Deviation from the normal, usual, or expected during mitotic spindle elongation." [DDB:pf]
is_a: DDPHENO:0001419 ! aberrant mitotic spindle organization
created_by: pfey
creation_date: 2012-04-16T01:52:48Z

[Term]
id: DDPHENO:0001487
name: delayed mitotic spindle elongation
def: "Late onset or slower progression of the mitotic spindle elongation." [DDB:pf]
is_a: DDPHENO:0001486 ! aberrant mitotic spindle elongation
created_by: pfey
creation_date: 2012-04-16T01:54:39Z

[Term]
id: DDPHENO:0001488
name: aberrant phagosome maturation
def: "Deviation from the normal, usual, or expected events during phagosome maturation." [DDB:pf]
is_a: DDPHENO:0001006 ! aberrant phagocytosis
created_by: pfey
creation_date: 2012-05-22T05:06:53Z

[Term]
id: DDPHENO:0001489
name: abolished phagosome acidification
def: "Complete inability for phagosome acidification." [DDB:pf]
is_a: DDPHENO:0001488 ! aberrant phagosome maturation
created_by: pfey
creation_date: 2012-05-22T05:10:55Z

[Term]
id: DDPHENO:0001490
name: precocious phagosome acidification
def: "Early onset or faster progression of phagosome acidification." [DDB:pf]
is_a: DDPHENO:0001488 ! aberrant phagosome maturation
created_by: pfey
creation_date: 2012-05-22T05:15:21Z

[Term]
id: DDPHENO:0001491
name: delayed phagosome acidification
def: "Late onset or slower progression of phagosome acidification." [DDB:pf]
is_a: DDPHENO:0001488 ! aberrant phagosome maturation
created_by: pfey
creation_date: 2012-05-22T05:19:42Z

[Term]
id: DDPHENO:0001492
name: delayed phagosome reneutralization
def: "Late onset or slower progression of phagosome reneutralization." [DDB:pf]
is_a: DDPHENO:0001488 ! aberrant phagosome maturation
created_by: pfey
creation_date: 2012-05-22T05:22:18Z

[Term]
id: DDPHENO:0001493
name: obsolete aberrant mitochondrion distribution
def: "OBSOLETE. Deviation from the normal, usual, or expected events during mitochondrion distribution." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2012-05-30T05:44:25Z

[Term]
id: DDPHENO:0001494
name: aberrant intracellular distribution of mitochondria
def: "Deviation from the normal, usual, or expected events during intracellular distribution of mitochondria." [DDB:pf]
synonym: "aberrant mitochondria positioning within cell" EXACT []
is_a: DDPHENO:0001234 ! aberrant mitochondrion organization
created_by: pfey
creation_date: 2012-05-30T05:45:34Z

[Term]
id: DDPHENO:0001495
name: decreased phagolysosome size
def: "Reduction in relative or proportional dimensions of the phagolysosome." [DDB:pf]
is_a: DDPHENO:0001222 ! aberrant phagolysosome formation
created_by: pfey
creation_date: 2012-05-30T05:58:22Z

[Term]
id: DDPHENO:0001496
name: increased phagolysosome size
def: "Increase in relative or proportional dimensions of the phagolysosome." [DDB:pf]
is_a: DDPHENO:0001222 ! aberrant phagolysosome formation
created_by: pfey
creation_date: 2012-05-30T05:59:28Z

[Term]
id: DDPHENO:0001497
name: abolished protein localization to cell surface
alt_id: DDPHENO:0000059
def: "Complete inability to localize a protein to the cell surface." [DDB:pf]
synonym: "abolished localization to cell surface" BROAD []
is_a: DDPHENO:0001393 ! abolished protein localization
is_a: DDPHENO:0001511 ! aberrant protein localization to cell surface
created_by: pfey
creation_date: 2012-09-26T05:18:28Z

[Term]
id: DDPHENO:0001498
name: decreased protein localization to cell surface
alt_id: DDPHENO:0000061
def: "Reduction in amount or accumulation of a protein on the cell surface." [DDB:pf]
synonym: "decreased localization to cell surface" BROAD []
xref: DDB:pf
is_a: DDPHENO:0001338 ! decreased protein localization
is_a: DDPHENO:0001511 ! aberrant protein localization to cell surface
created_by: pfey
creation_date: 2012-09-26T05:24:53Z

[Term]
id: DDPHENO:0001499
name: increased protein localization to cell surface
alt_id: DDPHENO:0000060
def: "Increase in amount or accumulation of a protein to the cell surface." [DDB:pf]
synonym: "increased localization to cell surface" BROAD []
xref: DDB:pf
is_a: DDPHENO:0001337 ! increased protein localization
is_a: DDPHENO:0001511 ! aberrant protein localization to cell surface
created_by: pfey
creation_date: 2012-09-26T05:36:48Z

[Term]
id: DDPHENO:0001500
name: aberrant protein stabilization
def: "Deviation from the normal, usual, or expected stabilization of proteins." [DDB:pf]
is_a: DDPHENO:0001241 ! aberrant protein level
created_by: pfey
creation_date: 2012-09-26T05:42:31Z

[Term]
id: DDPHENO:0001501
name: decreased protein stabilization
def: "Reduction in extent, amount, or degree of protein stabilization." [DDB:pf]
is_a: DDPHENO:0001500 ! aberrant protein stabilization
created_by: pfey
creation_date: 2012-09-26T05:44:26Z

[Term]
id: DDPHENO:0001502
name: increased protein stabilization
def: "Increase in extent, amount, or degree of protein stabilization." [DDB:pf]
is_a: DDPHENO:0001500 ! aberrant protein stabilization
created_by: pfey
creation_date: 2012-09-26T05:44:42Z

[Term]
id: DDPHENO:0001503
name: abolished protein stabilization
def: "Complete elimination of protein stabilization." [DDB:pf]
is_a: DDPHENO:0001500 ! aberrant protein stabilization
created_by: pfey
creation_date: 2012-09-26T05:44:58Z

[Term]
id: DDPHENO:0001504
name: aberrant response to cation stress
def: "Deviation from the normal, usual, or expected events during the response to cation stress." [DDB:pf]
is_a: DDPHENO:0001034 ! aberrant cellular response to stress
created_by: pfey
creation_date: 2012-10-04T14:20:48Z

[Term]
id: DDPHENO:0001505
name: aberrant cellular defense response
def: "Deviation from the normal, usual, or expected response triggered in response to the presence of a foreign body or the prevention/recovery from an infection." [DDB:pf]
is_a: DDPHENO:0001226 ! aberrant cellular response to extracellular stimulus
created_by: pfey
creation_date: 2012-11-01T15:29:41Z

[Term]
id: DDPHENO:0001506
name: obsolete aberrant defense response to a microorganism
def: "OBSOLETE. Deviation from the normal, usual, or expected response to the presence of a microorganism that acts to protect the cell." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2012-11-01T15:39:11Z

[Term]
id: DDPHENO:0001507
name: aberrant protein localization to cell cortex
alt_id: DDPHENO:0000054
def: "Deviation from the normal, usual, or expected events during localization of a protein to the cell cortex." [DDB:pf]
synonym: "aberrant localization to cell cortex" BROAD []
is_a: DDPHENO:0000672 ! aberrant protein localization to cell periphery
created_by: pfey
creation_date: 2012-11-21T14:21:05Z

[Term]
id: DDPHENO:0001508
name: abolished protein localization to cell cortex
alt_id: DDPHENO:0000055
def: "Complete inability to localize a protein to the cell cortex." [DDB:pf]
synonym: "abolished localization to cell cortex" BROAD []
is_a: DDPHENO:0000673 ! abolished protein localization to cell periphery
is_a: DDPHENO:0001507 ! aberrant protein localization to cell cortex
created_by: pfey
creation_date: 2012-11-21T14:57:02Z

[Term]
id: DDPHENO:0001509
name: decreased protein localization to cell cortex
alt_id: DDPHENO:0000057
def: "Reduction in amount or accumulation of a protein to the cell cortex." [DDB:pf]
synonym: "decreased localization to cell cortex" BROAD []
is_a: DDPHENO:0001338 ! decreased protein localization
is_a: DDPHENO:0001507 ! aberrant protein localization to cell cortex
created_by: pfey
creation_date: 2012-11-21T14:59:13Z

[Term]
id: DDPHENO:0001510
name: increased protein localization to cell cortex
alt_id: DDPHENO:0000056
def: "Increase in amount or accumulation of a protein to the cell cortex." [DDB:pf]
synonym: "increased localization to cell cortex" BROAD []
is_a: DDPHENO:0001337 ! increased protein localization
is_a: DDPHENO:0001507 ! aberrant protein localization to cell cortex
created_by: pfey
creation_date: 2012-11-21T15:00:30Z

[Term]
id: DDPHENO:0001511
name: aberrant protein localization to cell surface
alt_id: DDPHENO:0000058
def: "Deviation from the normal, usual, or expected events during localization of a protein to the cell surface." [DDB:pf]
synonym: "aberrant localization to cell surface" BROAD []
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2012-11-21T16:19:40Z

[Term]
id: DDPHENO:0001512
name: abolished protein localization to pseudopodium
alt_id: DDPHENO:0000093
def: "Complete inability to localize a protein pseudopodia." [DDB:pf]
synonym: "abolished localization to pseudopodium" BROAD []
is_a: DDPHENO:0001393 ! abolished protein localization
is_a: DDPHENO:0001412 ! aberrant protein localization to pseudopodium
created_by: pfey
creation_date: 2012-11-21T16:33:42Z

[Term]
id: DDPHENO:0001513
name: aberrant protein localization to microtubule organizing center
alt_id: DDPHENO:0000070
def: "Deviation from the normal, usual, or expected events during localization of a protein to the microtubule organizing center." [DDB:pf]
synonym: "aberrant localization to microtubule organizing center" BROAD []
synonym: "aberrant protein localization to the MTOC" EXACT []
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2012-11-21T16:41:09Z

[Term]
id: DDPHENO:0001514
name: aberrant protein localization to microtubules
alt_id: DDPHENO:0000074
def: "Deviation from the normal, usual, or expected events during localization of a protein to the microtubules." [DDB:pf]
synonym: "aberrant localization to microtubules" BROAD []
is_a: DDPHENO:0000471 ! aberrant protein localization
created_by: pfey
creation_date: 2012-11-21T16:42:51Z

[Term]
id: DDPHENO:0001515
name: aberrant mitochondrial fusion
def: "Deviation from the normal, usual, or expected events during mitochondrial fusion." [DDB:pf]
is_a: DDPHENO:0001234 ! aberrant mitochondrion organization
created_by: pfey
creation_date: 2012-12-04T16:26:23Z

[Term]
id: DDPHENO:0001516
name: decreased mitochondrial fusion
def: "Quantitative reduction of mitochondrial fusion." [DDB:pf]
is_a: DDPHENO:0001515 ! aberrant mitochondrial fusion
created_by: pfey
creation_date: 2012-12-04T16:28:41Z

[Term]
id: DDPHENO:0001517
name: increased mitochondrial fusion
def: "Quantitative increase in mitochondrial fusion." [DDB:pf]
is_a: DDPHENO:0001515 ! aberrant mitochondrial fusion
created_by: pfey
creation_date: 2012-12-04T16:29:02Z

[Term]
id: DDPHENO:0001518
name: aberrant mitochondrial fission
def: "Deviation from the normal, usual, or expected events during mitochondrial fission." [DDB:pf]
is_a: DDPHENO:0001234 ! aberrant mitochondrion organization
created_by: pfey
creation_date: 2012-12-04T16:29:22Z

[Term]
id: DDPHENO:0001519
name: decreased mitochondrial fission
def: "Quantitative reduction of mitochondrial fission." [DDB:pf]
is_a: DDPHENO:0001518 ! aberrant mitochondrial fission
created_by: pfey
creation_date: 2012-12-04T16:30:43Z

[Term]
id: DDPHENO:0001520
name: increased mitochondrial fission
def: "Quantitative increase in mitochondrial fission." [DDB:pf]
is_a: DDPHENO:0001518 ! aberrant mitochondrial fission
created_by: pfey
creation_date: 2012-12-04T16:31:04Z

[Term]
id: DDPHENO:0001521
name: aberrant cellular response to fluid shear stress
def: "Deviation from the normal, usual, or expected events during the cellular response to fluid shear stress." [DDB:pf]
synonym: "aberrant cellular response to mechanical stress" RELATED []
is_a: DDPHENO:0001034 ! aberrant cellular response to stress
created_by: pfey
creation_date: 2013-01-21T11:10:47Z

[Term]
id: DDPHENO:0001522
name: obsolete decreased resistance to fluid shear stress
def: "OBSOLETE. Decreased tolerance of the normal, usual, or expected events during the cellular response to fluid shear stress." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2013-01-21T11:22:51Z

[Term]
id: DDPHENO:0001523
name: obsolete increased resistance to fluid shear stress
def: "OBSOLETE. Increased tolerance of the normal, usual, or expected events during the cellular response to fluid shear stress." [DDB:pf]
is_obsolete: true
created_by: pfey
creation_date: 2013-01-21T11:23:21Z

[Term]
id: DDPHENO:0001524
name: aberrant chromatin assembly
def: "Deviation from the normal, usual, or expected during chromatin assembly." [DDB:pf]
is_a: DDPHENO:0001005 ! aberrant cellular metabolic process
created_by: pfey
creation_date: 2013-01-21T13:29:16Z

[Term]
id: DDPHENO:0001525
name: increased prestalk U cell differentiation
def: "Increase in extent, amount, or degree of differentiation into prestalk U cells." [DDB:pf]
synonym: "increased number of prestalk U cells" RELATED []
synonym: "increased number of pstU cells" RELATED []
synonym: "increased pstU cell differentiation" EXACT []
is_a: DDPHENO:0000169 ! increased prestalk cell differentiation
is_a: DDPHENO:0001527 ! aberrant prestalk U differentiation
created_by: pfey
creation_date: 2013-02-11T16:28:11Z

[Term]
id: DDPHENO:0001526
name: decreased prestalk U cell differentiation
def: "Reduction in extent, amount, or degree of differentiation into prestalk U cells." [DDB:pf]
synonym: "decreased number of prestalk U cells" RELATED []
synonym: "decreased number of pstU cells" RELATED []
synonym: "decreased pstU cell differentiation" EXACT []
is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation
is_a: DDPHENO:0001527 ! aberrant prestalk U differentiation
created_by: pfey
creation_date: 2013-02-11T16:32:31Z

[Term]
id: DDPHENO:0001527
name: aberrant prestalk U differentiation
def: "Deviation from the normal, usual, or expected events during differentiation of prestalk U cells." [DDB:pf]
synonym: "aberrant pstU differentiation" EXACT []
is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation
created_by: pfey
creation_date: 2013-02-11T16:46:03Z

[Term]
id: DDPHENO:0001528
name: abolished prestalk U cell differentiation
def: "Complete inability for differentiation of prestalk U cells." [DDB:pf]
synonym: "abolished pstU cell differentiation" EXACT []
is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation
is_a: DDPHENO:0001527 ! aberrant prestalk U differentiation
created_by: pfey
creation_date: 2013-02-11T16:56:55Z

[Term]
id: DDPHENO:0001529
name: aberrant regulation of vegetative growth
def: "Deviation from the normal, usual, or expected events during the regulation of vegetative growth." [DDB:pf]
synonym: "aberrant regulation of asexual reproduction" EXACT []
synonym: "aberrant regulation of cell proliferation" RELATED []
is_a: DDPHENO:0001084 ! aberrant vegetative growth
created_by: pfey
creation_date: 2013-02-15T10:39:43Z

[Term]
id: DDPHENO:0001530
name: aberrant negative regulation of vegetative growth
def: "Deviation from the normal, usual, or expected events during the negative regulation of vegetative growth." [DDB:pf]
synonym: "aberrant negative regulation of asexual reproduction" EXACT []
synonym: "aberrant negative regulation of cell proliferation" RELATED []
is_a: DDPHENO:0001529 ! aberrant regulation of vegetative growth
created_by: pfey
creation_date: 2013-02-15T10:44:33Z

[Term]
id: DDPHENO:0001531
name: abolished negative regulation of vegetative growth
def: "Complete inability to negatively regulate vegetative growth." [DDB:pf]
synonym: "abolished negative regulation of asexual reproduction" EXACT []
synonym: "abolished negative regulation of cell proliferation" RELATED []
is_a: DDPHENO:0001530 ! aberrant negative regulation of vegetative growth
created_by: pfey
creation_date: 2013-02-15T10:46:20Z

[Term]
id: DDPHENO:0001532
name: aberrant positive regulation of vegetative growth
def: "Deviation from the normal, usual, or expected events during the positive regulation of vegetative growth." [DDB:pf]
synonym: "aberrant positive regulation of asexual reproduction" EXACT []
synonym: "aberrant positive regulation of cell proliferation" RELATED []
is_a: DDPHENO:0001529 ! aberrant regulation of vegetative growth
created_by: pfey
creation_date: 2013-02-15T11:00:01Z

[Term]
id: DDPHENO:0001533
name: abolished positive regulation of vegetative growth
def: "Complete inability to positively regulate vegetative growth." [DDB:pf]
synonym: "abolished positive regulation of asexual reproduction" EXACT []
synonym: "abolished positive regulation of cell proliferation" RELATED []
is_a: DDPHENO:0001532 ! aberrant positive regulation of vegetative growth
created_by: pfey
creation_date: 2013-02-15T11:01:54Z

[Term]
id: DDPHENO:0001534
name: increased lysosomal pH
def: "Quantitative increase in lysosomal pH." [DDB:pf]
synonym: "lysosomal lumen pH elevation" RELATED []
is_a: DDPHENO:0001237 ! aberrant lysosome organization
created_by: pfey
creation_date: 2013-03-25T10:52:45Z

[Term]
id: DDPHENO:0001535
name: decreased phagosomal proteolysis
def: "Reduction in extent, amount, or degree of phagosomal proteolysis." [DDB:pf]
synonym: "decreased protein maturation by proteolysis in phagosome" EXACT []
synonym: "decreased protein processing in phagocytic vesicle" EXACT []
is_a: DDPHENO:0001006 ! aberrant phagocytosis
created_by: pfey
creation_date: 2013-03-25T11:01:42Z

[Term]
id: DDPHENO:0001536
name: aberrant nucleus organization
def: "Deviation from the normal, usual, or expected events during nucleus organization." [DDB:pf]
is_a: DDPHENO:0001043 ! aberrant organelle organization
created_by: pfey
creation_date: 2013-03-27T14:34:35Z

[Term]
id: DDPHENO:0010000
name: Dicty Phenotypes
def: "Phenotypes describing mutations in Dictyostelium." [DDB:pf]

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