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format-version: 1.2 date: 19:02:2010 11:15 saved-by: pfey auto-generated-by: OBO-Edit 2.0 default-namespace: Dicty Phenotypes remark: cvs version: $Revision: 1.186 $ [Term] id: DDPHENO:0000009 name: aberrant fruiting body morphology def: "Deviation from the normal, usual, or expected morphology of the fruiting body." [DDB:pg] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0000019 name: abolished culmination def: "Complete inability for culmination. " [DDB:pg] synonym: "culmination defective" RELATED [] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000026 name: development arrests at mound stage is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0000028 name: abolished stalk formation def: "Complete inability for formation of the stalk. " [DDB:pg] is_a: DDPHENO:0001012 ! aberrant stalk formation [Term] id: DDPHENO:0000032 name: increased sporulation def: "Increase in extent, amount, or degree of sporulation. " [DDB:pg] synonym: "increased number of spore cells" RELATED [] synonym: "increased number of spores" RELATED [] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000036 name: multiple tips is_a: DDPHENO:0000009 ! aberrant fruiting body morphology is_a: DDPHENO:0001431 ! aberrant tip formation [Term] id: DDPHENO:0000077 name: decreased fruiting body size def: "Reduction in relative or proportionate dimensions of the fruiting body." [DDB:pf] synonym: "small fruiting body" EXACT [] is_a: DDPHENO:0000009 ! aberrant fruiting body morphology [Term] id: DDPHENO:0000090 name: aberrant endocytosis def: "Deviation from the normal, usual, or expected events during endocytosis. " [DDB:pg] synonym: "endocytosis defect" RELATED [] is_a: DDPHENO:0001047 ! aberrant transport [Term] id: DDPHENO:0000094 name: spores inviable is_a: DDPHENO:0001046 ! aberrant spore germination [Term] id: DDPHENO:0000098 name: aberrant prestalk A cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prestalk A cells. " [DDB:pg] synonym: "aberrant pstA cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation [Term] id: DDPHENO:0000099 name: decreased chemotaxis rate def: "Reduction in extent, amount, or degree of chemotaxis rate during the locomotory response to a chemical concentration gradient." [DDB:kp] is_a: DDPHENO:0000148 ! decreased cell motility is_a: DDPHENO:0001122 ! aberrant chemotaxis is_a: DDPHENO:0001130 ! decreased taxis [Term] id: DDPHENO:0000102 name: increased number of aggregates def: "Quantitative increase in aggregates." [DDB:pg] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000108 name: increased intracellular glucose level def: "Increase in amount or accumulation of cytosolic glucose." [DDB:pg] synonym: "increased cytosolic glucose level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000109 name: increased cell-cell adhesion def: "Increase in extent, amount, or degree of cell-cell adhesion." [DDB:pg] is_a: DDPHENO:0000412 ! aberrant cell-cell adhesion [Term] id: DDPHENO:0000111 name: increased aggregate size alt_id: DDPHENO:0001018 def: "Increase in relative or proportionate dimensions of the aggregate." [DDB:pg] synonym: "aberrant negative regulation of aggregate size" RELATED [] is_a: DDPHENO:0001017 ! aberrant regulation of aggregate size [Term] id: DDPHENO:0000116 name: increased cell motility def: "Increase in extent, amount, or degree of cell motility. " [DD:pg] is_a: DDPHENO:0000264 ! aberrant cell motility [Term] id: DDPHENO:0000121 name: decreased intracellular glucose level def: "Reduction in extent, amount or accumulation of cytosolic glucose." [DDB:pg] synonym: "decreased cytosolic glucose level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000123 name: decreased cAMP-induced cGMP pulse alt_id: DDPHENO:0000199 def: "Reduction in extent, amount, or degree of cGMP pulse in response to cAMP." [DDB:pg] synonym: "merged_defective in cAMP-dependent activation of guanylyl cyclase (GC)" EXACT [] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000124 name: increased cAMP-induced cAMP pulse def: "Increase in extent, amount, or degree of cAMP pulse in response to cAMP. " [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000126 name: increased cAMP-induced cGMP pulse def: "Increase in extent, amount, or degree of cGMP pulse in response to cAMP. " [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000130 name: decreased cAMP-induced cAMP pulse def: "Reduction in extent, amount, or degree of cAMP pulse in response to cAMP." [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000131 name: increased secretion of counting factor (CF) def: "Increase in extent, amount, or degree of secretion of counting factor (CF). " [DDB:pg] is_a: DDPHENO:0001001 ! aberrant initiation of development [Term] id: DDPHENO:0000132 name: increased basal F-actin level def: "Increase in amount or accumulation of basal F-actin. " [DDB:pg] synonym: "increased basal filamentous actin level" EXACT [] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation [Term] id: DDPHENO:0000133 name: increased ABP120 protein level def: "Increase in amount or accumulation of actin-binding protein." [DDB:pg] synonym: "increased level of ABP" EXACT [] is_obsolete: true [Term] id: DDPHENO:0000134 name: increased myosin II assembly def: "Increase in extent, amount, or degree of assembly of myosin II. " [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation [Term] id: DDPHENO:0000135 name: decreased ABP120 protein level def: "Reduction in amount or accumulation of actin-binding protein." [DDB:pg] synonym: "decreased level of ABP protein" EXACT [] is_obsolete: true [Term] id: DDPHENO:0000136 name: decreased myosin II assembly def: "Reduction in extent, amount, or degree of myosin II assembly. " [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation [Term] id: DDPHENO:0000137 name: decreased basal F-actin level def: "Reduction in amount or accumulation of basal F-actin." [DDB:pg] synonym: "decreased basal filamentous actin level" EXACT [] is_a: DDPHENO:0000151 ! aberrant F-actin organization [Term] id: DDPHENO:0000138 name: decreased cell-cell adhesion def: "Reduction in extent, amount, or degree of cell-cell adhesion." [DDB:pg] is_a: DDPHENO:0000412 ! aberrant cell-cell adhesion [Term] id: DDPHENO:0000139 name: decreased sexual fusion def: "Reduction in extent, amount, or degree of sexual fusion. " [DDB:pg] is_a: DDPHENO:0001010 ! aberrant macrocyst differentiation [Term] id: DDPHENO:0000140 name: weak slime trail is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000142 name: wild type synonym: "no known phenotype" RELATED [] is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0000145 name: decreased spore viability def: "Reduction in extent, amount, or degree of spore viabilty." [DDB:pg] is_a: DDPHENO:0001046 ! aberrant spore germination [Term] id: DDPHENO:0000148 name: decreased cell motility alt_id: DDPHENO:0000386 def: "Reduction in extent, amount, or degree of cell motility." [DDB:pg] synonym: "decreased random cell locomotion" RELATED [] is_a: DDPHENO:0000264 ! aberrant cell motility [Term] id: DDPHENO:0000149 name: aberrant cytokinesis def: "Deviation from the normal, usual, or expected events during cytokinesis." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0000151 name: aberrant F-actin organization def: "Deviation from the normal, usual, or expected events during actin filament organization." [DDB:pg] synonym: "actin filament organization" EXACT [] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation [Term] id: DDPHENO:0000154 name: aberrant development alt_id: DDPHENO:0000143 alt_id: DDPHENO:0000374 alt_id: DDPHENO:0000380 def: "Deviation from the normal, usual, or expected events during development." [DDB:pg] synonym: "merged_development hypersensitive to ammonia" EXACT [] synonym: "merged_development is resistant to Li+" EXACT [] synonym: "merged_increased sensitivity to lithium" EXACT [] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000155 name: development arrests at tipped mound stage is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0000156 name: delayed aggregation alt_id: DDPHENO:0000502 alt_id: DDPHENO:0000548 def: "Late onset or slower progression through aggregation." [DDB:pg] synonym: "aggregation defective" RELATED [] synonym: "merged_delayed aggregation in the presence of ammonia" EXACT [] synonym: "merged_delayed aggregation under submerged conditions" EXACT [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000157 name: delayed tip formation def: "Late onset or slower progression through the formation of the tip." [DDB:pg] is_a: DDPHENO:0000162 ! delayed development is_a: DDPHENO:0001431 ! aberrant tip formation [Term] id: DDPHENO:0000158 name: decreased aggregate size alt_id: DDPHENO:0001019 def: "Reduction in relative or proportionate dimensions of the aggregate." [DDB:pg] synonym: "aberrant positive regulation of aggregate size" RELATED [] is_a: DDPHENO:0001017 ! aberrant regulation of aggregate size [Term] id: DDPHENO:0000159 name: development arrests at loose aggregate stage alt_id: DDPHENO:0000505 alt_id: DDPHENO:0000506 alt_id: DDPHENO:0000507 synonym: "development arrests at loose aggregate stage in the presence of EGTA" EXACT [] synonym: "development arrests at loose aggregate stage in the presence of TMB-8" EXACT [] synonym: "merged_development arrests at loose aggregate stage in the presence of lithium" EXACT [] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0000160 name: increased slug size def: "Increase in relative or proportionate dimensions of the slug. " [DDB:pg] is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000161 name: delayed culmination def: "Late onset or slower progression through culmination. " [DDBB:pg] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000162 name: delayed development alt_id: DDPHENO:0000418 alt_id: DDPHENO:0000508 def: "Late onset or slower progression through development." [DDB:pg] synonym: "merged_delayed development in the presence of gossypol" EXACT [] synonym: "merged_delayed development in the presence of lithium" EXACT [] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0000163 name: aberrant spore morphology def: "Deviation from the normal, usual, or expected morphology of the spore. " [DDB:pg] is_a: DDPHENO:0000236 ! aberrant cell morphology is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000165 name: increased stalk length def: "Having a relative long stalk." [DDB:pg] synonym: "long stalk" EXACT [] xref: PATO:0000573 is_a: DDPHENO:0000510 ! aberrant stalk morphogenesis [Term] id: DDPHENO:0000166 name: decreased sorus size def: "Reduction in relative or proportionate dimensions of the sorus." [DDB:pg] synonym: "small sori" RELATED [] is_a: DDPHENO:0000384 ! aberrant sorus morphology [Term] id: DDPHENO:0000167 name: precocious development def: "Early onset or faster progression through development." [DDB:pg] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0000168 name: development arrests at slug stage is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000169 name: increased prestalk cell differentiation def: "Increase in extent, amount, or degree of prestalk cell differentiation." [DDB:pg] synonym: "increased number of prestalk cells" RELATED [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation [Term] id: DDPHENO:0000170 name: increased prespore cell differentiation def: "Increase in extent, amount, or degree of differentiation into prespore cells. " [DDB:pg] synonym: "increased number of prespore cells" RELATED [] is_a: DDPHENO:0001025 ! aberrant prespore cell differentiation [Term] id: DDPHENO:0000171 name: increased growth rate is_a: DDPHENO:0001084 ! aberrant vegetative growth [Term] id: DDPHENO:0000172 name: obsolete_insensitive to ammonia def: "OBSOLETE." [DDB:kp] is_obsolete: true [Term] id: DDPHENO:0000173 name: precocious spore germination def: "Early onset or faster progression of spores through germination. " [DDB:pg] is_a: DDPHENO:0001046 ! aberrant spore germination [Term] id: DDPHENO:0000175 name: decreased prespore cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prespore cells. " [DDB:pg] synonym: "decreased number of prespore cells" RELATED [] is_a: DDPHENO:0001025 ! aberrant prespore cell differentiation [Term] id: DDPHENO:0000176 name: increased prestalk O cell differentiation def: "Increase in extent, amount, or degree of differentiation into prestalk O cells. " [DDB:pg] synonym: "increased number of prestalk O cells" RELATED [] synonym: "increased number of pstO cells" EXACT [] is_a: DDPHENO:0000169 ! increased prestalk cell differentiation is_a: DDPHENO:0001024 ! aberrant prestalk O cell differentiation [Term] id: DDPHENO:0000178 name: precocious tip formation def: "Early onset or faster progression through tip formation." [DDB:pg] is_a: DDPHENO:0000167 ! precocious development is_a: DDPHENO:0001431 ! aberrant tip formation [Term] id: DDPHENO:0000181 name: abolished slug migration def: "Complete inability for slugs to migrate. " [DDB:pg] is_a: DDPHENO:0001077 ! aberrant slug migration [Term] id: DDPHENO:0000183 name: decreased number of astral microtubules def: "Reduction in extent, amount, or degree of astral microtubules." [DDB:pf] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0000184 name: decreased length of astral microtubules is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation [Term] id: DDPHENO:0000185 name: increased sensitivity to nocodazole is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000187 name: aberrant cell-substrate adhesion def: "Deviation from the normal, usual, or expected events during cell-substrate adhesion." [DDB:pg] synonym: "aberrant substrate adhesion" RELATED [] synonym: "defective substrate adhesion" RELATED [] is_a: DDPHENO:0001044 ! aberrant cell adhesion [Term] id: DDPHENO:0000188 name: decreased phagocytosis def: "Reduction in extent, amount, or degree of phagocytosis." [DDB:pg] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0000191 name: decreased prestalk cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prestalk cells." [DDB:pg] synonym: "decreased number of prestalk cells" RELATED [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation [Term] id: DDPHENO:0000192 name: abolished prestalk O cell differentation def: "Complete inability for differentiation of prestalk O cells. " [DDB:pg] is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation is_a: DDPHENO:0001024 ! aberrant prestalk O cell differentiation [Term] id: DDPHENO:0000193 name: abolished DIF production def: "Complete inability for DIF production. " [DDB:pg] synonym: "abolished DIF-1 production" NARROW [] synonym: "abolished differentiation inducing factor production" EXACT [] is_a: DDPHENO:0001095 ! aberrant DIF production [Term] id: DDPHENO:0000195 name: decreased stalk cell differentiation def: "Reduction in extent, amount, or degree of differentiation into stalk cells. " [DDB:pg] synonym: "decreased number of stalk cells" EXACT [] is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation [Term] id: DDPHENO:0000196 name: increased protein kinase A activity def: "Increase in extent, amount, or degree of protein kinase A activity." [DDB:pg] synonym: "increased PKA activity" EXACT [DDB:kp] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0000197 name: increased GTP-gamma-S-stimulated guanylyl cyclase activity def: "Increase in extent, amount, or degree of GTP-gamma-S-stimulated guanylyl cyclase activity." [DDB:pg] synonym: "increased GTP-gamma-S-stimulated GC activity" EXACT [] is_a: DDPHENO:0001287 ! increased guanylyl cyclase activity [Term] id: DDPHENO:0000198 name: aberrant activation of adenylate cyclase activity def: "Deviation from the normal, usual, or expected events during the activation of adenylate cyclase." [DDB:pg] comment: Replaced "defective in activation of adenylate cyclase (ACA)" with "aberrant activation of adenylate cyclase (ACA)"; annotations shoud be changed to "decreased" or "abolished" activation of adenylate cyclase. PG 10-11-2006 synonym: "aberrant activation of ACA" EXACT [] synonym: "defective in activation of adenylate cyclase (ACA)" RELATED [] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation is_a: DDPHENO:0001304 ! aberrant regulation of adenylate cyclase activity [Term] id: DDPHENO:0000200 name: decreased GTP-gamma-S-stimulated guanylyl cyclase activity def: "Reduction in extent, amount, or degree of GTP-gamma-S-stimulated guanylyl cyclase activity." [DDB:pg] synonym: "decreased GTP-gamma-S-stimulated GC activity" EXACT [] is_a: DDPHENO:0001288 ! decreased guanylyl cyclase activity [Term] id: DDPHENO:0000201 name: decreased glycogen synthase kinase 3 activity def: "Reduction in extent, amount, or degree of glycogen synthase kinase 3 activity." [DDB:pg] synonym: "decreased GSK3 activity" EXACT [DDB:kp] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0000202 name: decreased growth rate in suspension is_a: DDPHENO:0000394 ! decreased growth rate [Term] id: DDPHENO:0000203 name: increased number of microtubule-organizing centers def: "Quantitative increase in microtubule-organizing centers. " [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation [Term] id: DDPHENO:0000204 name: decreased extracellular counting factor component(s) level def: "Reduction in amount or accumulation of extracellular counting factor component(s). " [DDB:pg] synonym: "decreased level of extracellular CF component(s)" EXACT [] is_a: DDPHENO:0001001 ! aberrant initiation of development [Term] id: DDPHENO:0000205 name: decreased extracellular CF50 level is_a: DDPHENO:0001001 ! aberrant initiation of development [Term] id: DDPHENO:0000206 name: precocious aggregation def: "Early onset or faster progression through aggregation. " [DDB:pg] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000207 name: long fingers is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000208 name: thin fingers is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000209 name: aberrant response to osmotic stress def: "Deviation from the normal, usual, or expected events during the response to osmotic stress." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000210 name: delayed slug formation def: "Late onset or slower progression through the formation of the slug. " [DDB:pg] is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000211 name: aberrant cellular response to nitrogen starvation def: "Deviation from the normal, usual, or expected events during the cellular response to nitrogen starvation." [DDB:pf] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000212 name: aberrant macroautophagy def: "Deviation from the normal, usual, or expected events during macroautophagy." [DDB:pf] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0000213 name: increased cell-substrate adhesion def: "Increase in extent, amount, or degree of cell-substrate adhesion. " [DDB:pg] synonym: "increased substrate adhesion" RELATED [] is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion [Term] id: DDPHENO:0000214 name: precocious sporulation def: "Early onset or faster progression through sporulation. " [DDB:pg] synonym: "precocious spore differentiation" EXACT [] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000215 name: spores hypersensitive to H2O2 (peroxide) is_a: DDPHENO:0001046 ! aberrant spore germination [Term] id: DDPHENO:0000216 name: aberrant spore coat morphology def: "Deviation from the normal, usual, or expected morphology of the spore coat. " [DDB:pg] is_a: DDPHENO:0000163 ! aberrant spore morphology [Term] id: DDPHENO:0000221 name: abolished growth in suspension is_a: DDPHENO:0000302 ! inviable [Term] id: DDPHENO:0000222 name: aberrant phototaxis def: "Deviation from the normal, usual, or expected events during the response to light. " [DDB:pf] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0000223 name: aberrant thermotaxis def: "Deviation from the normal, usual, or expected events during the response to temperature changes. " [DDB:pf] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0000225 name: decreased slug migration def: "Reduction in extent, amount, or degree of slug migration. " [DDB:pg] is_a: DDPHENO:0001077 ! aberrant slug migration [Term] id: DDPHENO:0000226 name: increased prestalk A cell differentiation def: "Increase in extent, amount, or degree of differentiation into prestalk A cells. " [DDB:pg] synonym: "increased number of prestalk A cells" RELATED [] synonym: "increased number of pstA cells" EXACT [] is_a: DDPHENO:0000098 ! aberrant prestalk A cell differentiation is_a: DDPHENO:0000169 ! increased prestalk cell differentiation [Term] id: DDPHENO:0000230 name: aberrant endosome morphology def: "Deviation from the normal, usual, or expected morphology of the endosome." [DDB:pg] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0000232 name: decreased spore germination def: "Reduction in extent, amount, or degree of spore germination." [DDB:pg] is_a: DDPHENO:0001046 ! aberrant spore germination [Term] id: DDPHENO:0000233 name: aberrant contractile vacuole organization and biogenesis is_a: DDPHENO:0001041 ! aberrant vacuole organization and biogenesis [Term] id: DDPHENO:0000234 name: aberrant mitosis def: "Deviation from the normal, usual, or expected events during mitosis." [DDB:pg] is_a: DDPHENO:0001418 ! aberrant cell cycle [Term] id: DDPHENO:0000235 name: increased aneuploidy def: "Increase in extent, amount, or degree of aneuploidity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000236 name: aberrant cell morphology def: "Deviation from the normal, usual, or expected morphology of a cell." [DDB:pg] comment: child of GO:0000902 : cellular morphogenesis. is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0000259 name: abolished growth in axenic medium is_a: DDPHENO:0000302 ! inviable [Term] id: DDPHENO:0000260 name: decreased sorting to prestalk region def: "Reduction in extent, amount, or degree of cell sorting to prestalk region. " [DDB:pg] is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000261 name: abolished prestalk cell differentiation in response to DIF-1 def: "Complete inability for prestalk cell differentiation in response to DIF-1. " [DDB:pg] is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation [Term] id: DDPHENO:0000262 name: decreased prestalk O cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prestalk O cells. " [DDB:pg] synonym: "decreased number of prestalk O cells" RELATED [] synonym: "decreased pstO cell differentiation" EXACT [] is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation is_a: DDPHENO:0001024 ! aberrant prestalk O cell differentiation [Term] id: DDPHENO:0000263 name: aberrant nucleus morphology def: "Deviation from the normal, usual, or expected morphology of the nucleus." [DDB:pg] synonym: "aberrant nuclear morphology" EXACT [] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0000264 name: aberrant cell motility def: "Deviation from the normal, usual, or expected events during cell motility." [DDB:pg] comment: child of GO:0006928 : cell motility is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0000265 name: aberrant myosin II organization def: "Deviation from the normal, usual, or expected events during myosin II organization. " [DDB:pg] is_a: DDPHENO:0000236 ! aberrant cell morphology [Term] id: DDPHENO:0000269 name: increased basal disc size def: "Increase in relative or proportionate dimensions of the basal disc." [DDB:pg] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0000270 name: increased number of tubular mitochondria def: "Quantitative increase in tubular mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular. " [DDB:pg, PMID:14665465] is_a: DDPHENO:0000272 ! increased number of mitochondria [Term] id: DDPHENO:0000271 name: decreased number of mitochondria def: "Quantitative reduction in mitochondria." [DDB:pg] is_a: DDPHENO:0001234 ! aberrant mitochondrion organization and biogenesis [Term] id: DDPHENO:0000272 name: increased number of mitochondria def: "Quantitative increase in mitochondria." [DDB:pg] is_a: DDPHENO:0001234 ! aberrant mitochondrion organization and biogenesis [Term] id: DDPHENO:0000273 name: decreased SDF production def: "Reduction in extent, amount, or degree of production of SDF-1 or SDF-2, peptides that promote terminal spore differentiation" [DDB:pg] synonym: "decreased spore differentiation factor production" RELATED [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0000274 name: abolished SDF production def: "Complete inability for the production of SDF-1 or SDF-2, peptides that promote terminal spore differentiation." [DDB:pg] synonym: "abolished spore differentiation factor production" RELATED [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0000275 name: abolished growth on bacterial plates is_a: DDPHENO:0000302 ! inviable [Term] id: DDPHENO:0000276 name: decreased sensitivity to DNA-damaging agents is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000300 name: decreased gene expression alt_id: DDPHENO:0000174 alt_id: DDPHENO:0000189 alt_id: DDPHENO:0000220 alt_id: DDPHENO:0000267 def: "Reduction in extent, amount, or degree of gene expression." [DDB:pg] synonym: "merged_decreased expression of aggregation genes" NARROW [DDB:kp] synonym: "merged_decreased expression of prespore genes" NARROW [DDB:kp] synonym: "merged_decreased expression of prestalk genes" NARROW [DDB:kp] synonym: "merged_decreased expression of spore genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0000301 name: increased gene expression alt_id: DDPHENO:0000114 alt_id: DDPHENO:0000224 alt_id: DDPHENO:0000266 alt_id: DDPHENO:0000372 def: "Increase in extent, amount, or degree of gene expression. " [DDB:pg] synonym: "merged_increased discoidin level" NARROW [DDB:kp] synonym: "merged_increased expression of post-aggregative genes" NARROW [DDB:kp] synonym: "merged_increased expression of prespore genes" NARROW [DDB:kp] synonym: "merged_increased expression of prestalk genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0000302 name: inviable alt_id: DDPHENO:0001060 def: "Complete inability for cells to grow and divide. " [DDB:pg] synonym: "abolished growth" EXACT [] is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0000303 name: increased actin bundle formation def: "Increase in extent, amount, or degree of actin bundle formation. " [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation [Term] id: DDPHENO:0000304 name: increased membrane ruffling def: "Increase in extent, amount, or degree of membrane ruffling." [DDB:pg] is_a: DDPHENO:0001043 ! aberrant organelle organization and biogenesis [Term] id: DDPHENO:0000305 name: abolished down-regulation of growth phase genes def: "Complete inability to down-regulate growth pahse genes during development." [DDB:pg] is_a: DDPHENO:0001001 ! aberrant initiation of development [Term] id: DDPHENO:0000373 name: decreased growth rate on bacterial plates is_a: DDPHENO:0001096 ! decreased growth rates on solid surfaces [Term] id: DDPHENO:0000376 name: abolished filopodium formation def: "Complete inability to form pseudopods. " [DDB:pg] is_a: DDPHENO:0001028 ! aberrant filopodium formation [Term] id: DDPHENO:0000377 name: increased filopodium formation def: "Increase in extent, amount, or degree of formation of filopodia. " [DDB:pg] is_a: DDPHENO:0001028 ! aberrant filopodium formation [Term] id: DDPHENO:0000378 name: decreased lateral pseudopod suppression def: "Reduction in extent, amount, or degree of suppression of lateral pseudopods." [DD:pg] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0000379 name: decreased cell size def: "Reduction in relative or proportionate dimensions of the cell." [DDB:pg] is_a: DDPHENO:0000236 ! aberrant cell morphology [Term] id: DDPHENO:0000381 name: increased sensitivity to TMB-8 is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000382 name: obsolete_aberrant morphology def: "OBSOLETE." [DDB:kp] is_obsolete: true [Term] id: DDPHENO:0000383 name: decreased stalk length def: "Having a relative short stalk." [DDB:pg] synonym: "short stalk" EXACT [] xref: PATO:0000574 is_a: DDPHENO:0000510 ! aberrant stalk morphogenesis [Term] id: DDPHENO:0000384 name: aberrant sorus morphology def: "Deviation from the normal, usual, or expected morphology of the sorus." [DDB:pg] synonym: "aberrant spore head morphology" EXACT [] is_a: DDPHENO:0000009 ! aberrant fruiting body morphology [Term] id: DDPHENO:0000385 name: abolished cytokinesis def: "Complete inability for cytokinesis." [DDB:pg] is_a: DDPHENO:0000149 ! aberrant cytokinesis [Term] id: DDPHENO:0000387 name: abolished prespore cell division def: "Complete inability for division of prespore cells." [DDB:pg] is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000388 name: abolished vacuolation def: "Complete inability for vacuolation." [DDB:pg] is_a: DDPHENO:0001278 ! aberrant vacuolation [Term] id: DDPHENO:0000389 name: increased sorus size def: "Increase in relative or proportionate dimensions of the sorus." [DDB:pg] synonym: "large sori" EXACT [] is_a: DDPHENO:0000384 ! aberrant sorus morphology [Term] id: DDPHENO:0000390 name: translucent sorus synonym: "translucent sori" RELATED [] is_a: DDPHENO:0000384 ! aberrant sorus morphology [Term] id: DDPHENO:0000391 name: obsolete_partial suppression of tagB mutation def: "OBSOLETE." [DDB:kp] is_obsolete: true [Term] id: DDPHENO:0000392 name: decreased cell polarity def: "Reduction in extent, amount, or degree of cell polarity." [DDB:pg] is_a: DDPHENO:0001029 ! aberrant establishment and/or maintenance of cell polarity [Term] id: DDPHENO:0000393 name: decreased cell-substrate adhesion def: "Reduction in extent, amount, or degree of cell-substrate adhesion. " [DDB:pg] synonym: "decreased substrate adhesion" RELATED [] is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion [Term] id: DDPHENO:0000394 name: decreased growth rate alt_id: DDPHENO:0000417 alt_id: DDPHENO:0000435 alt_id: DDPHENO:0000436 alt_id: DDPHENO:0000511 synonym: "merged_decreased growth rate at low cell density" EXACT [] synonym: "merged_decreased growth rate in suspension in the presence of lithium" EXACT [] synonym: "merged_decreased growth rate in the presence of gossypol" EXACT [] synonym: "merged_decreased growth rate in the presence of ion chelators" EXACT [] is_a: DDPHENO:0001084 ! aberrant vegetative growth [Term] id: DDPHENO:0000395 name: decreased activation of protein kinase B def: "Reduction in extent, amount, or degree of phosphorylation of protein kinase B." [DDB:pg] comment: Not sure this is legitimate. See SF for an item on PKB; I think it's a gee product. synonym: "decreased activation of PKB" RELATED [] synonym: "decreased phosphorylation of PkbA (Akt/PKB)" RELATED [] is_a: DDPHENO:0001058 ! decreased protein kinase activation [Term] id: DDPHENO:0000396 name: decreased growth rate in liquid medium on solid sufaces is_a: DDPHENO:0001096 ! decreased growth rates on solid surfaces [Term] id: DDPHENO:0000397 name: aberrant cytoskeleton organisation def: "Deviation from the normal, usual, or expected events during cytoskeleton organization." [DDB:pg] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0000398 name: obsolete_no synthetic interaction observed between rasS and gefB def: "OBSOLETE." [DDB:kp] is_obsolete: true [Term] id: DDPHENO:0000399 name: decreased rate of endocytosis def: "Reduction in extent, amount, or degree of endocytosis. " [DDB:pg] is_a: DDPHENO:0000090 ! aberrant endocytosis [Term] id: DDPHENO:0000400 name: increased chemotaxis rate def: "Increase in extent, amount, or degree of chemotaxis rate during the locomotory response to a chemical concentration gradient." [DDB:kp] is_a: DDPHENO:0000116 ! increased cell motility is_a: DDPHENO:0001122 ! aberrant chemotaxis is_a: DDPHENO:0001129 ! increased taxis [Term] id: DDPHENO:0000401 name: increased resistance to cisplatin is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000402 name: increased intracellular cAMP level def: "Increase in amount or accumulation of intracellular cAMP." [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000405 name: increased phagocytosis def: "Increase in extent, amount, or degree of phagocytosis. " [DDB:pg] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0000406 name: increased cell size def: "Increase in relative or proportionate dimensions of the cell." [DDB:pg] is_a: DDPHENO:0000236 ! aberrant cell morphology [Term] id: DDPHENO:0000407 name: decreased chemoattractant-mediated F-actin polymerization def: "Reduction in extent, amount, or degree of F-actin polymerization in response to chemoattractant." [DDB:pg] is_a: DDPHENO:0000151 ! aberrant F-actin organization [Term] id: DDPHENO:0000408 name: increased resistance to carboplatin is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000409 name: increased sensitivity to carboplatin is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000410 name: increased sensitivity to cisplatin is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000411 name: increased resistance to heat shock is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000412 name: aberrant cell-cell adhesion def: "Deviation from the normal, usual, or expected events during cell-cell adhesion." [DDB:pg] is_a: DDPHENO:0001044 ! aberrant cell adhesion [Term] id: DDPHENO:0000413 name: aberrant microtubule cytoskeleton organization def: "Deviation from the normal, usual, or expected events during organization of the microtubule cytoskeleton. " [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation [Term] id: DDPHENO:0000414 name: decreased resistance to heat shock is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000416 name: decreased growth rate under Ca2+ stress is_a: DDPHENO:0000394 ! decreased growth rate [Term] id: DDPHENO:0000420 name: decreased cAMP-induced Ca2+ influx is_a: DDPHENO:0001118 ! aberrant signal transduction [Term] id: DDPHENO:0000421 name: delayed cAMP-induced Ca2+ influx is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000422 name: decreased Ca2+-induced Ca2+ influx is_a: DDPHENO:0001118 ! aberrant signal transduction [Term] id: DDPHENO:0000423 name: decreased infection rate by Legionella pneumophila def: "Reduction in extent, amount, or degree of the infection rate by Legionella pneumophila." [DDB:pf] synonym: "increased resistance to infection by Legionella pneumophila" RELATED [] is_a: DDPHENO:0001195 ! decreased infection rate by a microorganism [Term] id: DDPHENO:0000424 name: abolished sporulation def: "Complete inability for sporulation. " [DDB:pg] synonym: "abolished spore differentiation" EXACT [] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000425 name: increased sensitivity to H2O2 (peroxide) is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000426 name: increased sensitivity to UV light is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000427 name: increased sensitivity to mitomycin C (MMC) is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000428 name: decreased fatty acid level def: "Reduction in extent, amount or accumulation of fatty acid." [DDB:pg] synonym: " synonym: "decreased fatty acid accumulation" RELATED [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000429 name: aberrant vesicle coat assembly def: "Deviation from the normal, usual, or expected process of vesicle coat assembly." [DDB:pg] is_a: DDPHENO:0001043 ! aberrant organelle organization and biogenesis [Term] id: DDPHENO:0000430 name: decreased pinocytosis def: "Reduction in extent, amount, or degree of pinocytosis. " [DDD:pg] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000431 name: cell cycle arrest is_a: DDPHENO:0001418 ! aberrant cell cycle [Term] id: DDPHENO:0000432 name: aberrant glycogen metabolism def: "Deviation from the normal, usual, or expected events during glycogen metabolism." [DDB:pg] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0000433 name: increased secretion of lysosomal enzyme def: "Increase in extent, amount, or degree of secretion of lysosomal enzyme." [DDB:pg] is_a: DDPHENO:0001232 ! increased protein secretion [Term] id: DDPHENO:0000434 name: aberrant pinosome maturation def: "Deviation from the normal, usual, or expected events during pinosome maturation." [DDB:pf] is_a: DDPHENO:0001043 ! aberrant organelle organization and biogenesis [Term] id: DDPHENO:0000437 name: decreased actin nucleation on plasma membranes def: "Reduction in extent, amount, or degree of actin nucleation on plasma membranes. " [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation [Term] id: DDPHENO:0000438 name: uracil auxotroph is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000439 name: resistant to 5-fluoroorotic acid (5-FOA) is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000440 name: thymidine auxotroph is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000441 name: increased extracellular of CF50 level is_a: DDPHENO:0001001 ! aberrant initiation of development [Term] id: DDPHENO:0000442 name: increased extracellular counting factor component(s) level def: "Increase in amount or accumulation of extracellular counting factor component(s)." [DDB:pg] synonym: "increased level of extracellular CF component(s)" EXACT [] is_a: DDPHENO:0001001 ! aberrant initiation of development [Term] id: DDPHENO:0000443 name: decreased secretion of lysosomal enzyme def: "Reduction in extent, amount, or degree of secretion of lysosomal enzyme." [DDB:pg] is_a: DDPHENO:0001233 ! decreased protein secretion [Term] id: DDPHENO:0000444 name: increased intracellular counting factor component(s) level def: "Increase in amount or accumulation of intracellular counting factor component(s). " [DDB:pg] synonym: "increased level of intracellular CF component(s)" EXACT [] is_a: DDPHENO:0001001 ! aberrant initiation of development [Term] id: DDPHENO:0000445 name: increased slug migration def: "Increase in extent, amount, or degree of migration of slugs. " [DDB:pg] is_a: DDPHENO:0001077 ! aberrant slug migration [Term] id: DDPHENO:0000446 name: aberrant mound color def: "Deviation from the normal, usual, or expected mound color." [DDB:pg] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0000447 name: increased myosin protein level def: "Increase in amount or accumulation of myosin." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000448 name: increased pinocytosis def: "Increase in extent, amount, or degree of pinocytosis. " [DDB:pg] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000449 name: obsolete_no synthetic interaction def: "OBSOLETE." [DDB:kp] is_obsolete: true [Term] id: DDPHENO:0000450 name: decreased number of aggregates def: "Quantitative reduction in aggregates." [DDB:pg] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000451 name: increased number of peripheral cells during sexual reproduction def: "Quantitative increase in peripheral cells during sexual reproduction. " [DDB:pg] is_a: DDPHENO:0001010 ! aberrant macrocyst differentiation [Term] id: DDPHENO:0000452 name: small macrocysts is_a: DDPHENO:0001010 ! aberrant macrocyst differentiation [Term] id: DDPHENO:0000453 name: abolished localization of protein to the nucleus def: "Complete inability for a protein to localize to the nucleus." [DDB:pf, DDB:pg] synonym: "abolished nuclear localization" NARROW [] synonym: "abolished nuclear protein localization" EXACT [] is_a: DDPHENO:0001336 ! aberrant localization of protein to the nucleus is_a: DDPHENO:0001393 ! abolished protein localization [Term] id: DDPHENO:0000454 name: decreased accumulation of cGMP is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000455 name: increased accumulation of cGMP is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000456 name: increased basal phosphorylated actin level def: "Increase in amount or accumulation of phosphorylated actin." [DDB:pg] is_a: DDPHENO:0000457 ! aberrant phosphorylation of actin is_a: DDPHENO:0001343 ! increased protein phosphorylation [Term] id: DDPHENO:0000457 name: aberrant phosphorylation of actin def: "Deviation from the normal, usual, or expected events during actin phosphorylation." [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organisation is_a: DDPHENO:0001342 ! aberrant protein phosphorylation [Term] id: DDPHENO:0000458 name: abolished growth in acidic medium is_a: DDPHENO:0000302 ! inviable [Term] id: DDPHENO:0000459 name: increased F-actin polymerization def: "Increase in extent, amount, or degree of F-actin polymerization." [DDB:pg] is_a: DDPHENO:0001445 ! aberrant F-actin polymerization [Term] id: DDPHENO:0000460 name: increased growth rate on bacterial plates is_a: DDPHENO:0000171 ! increased growth rate [Term] id: DDPHENO:0000461 name: decreased intracellular pH level def: "Reduction in amount or accumulation of hydrogen ions in the cell." [DDB:pg] synonym: "decreased cytosolic pH level" EXACT [] is_a: DDPHENO:0001455 ! aberrant intracellular pH level [Term] id: DDPHENO:0000462 name: decreased filopodium formation def: "Reduction in extent, amount, or degree of filopodium formation. " [DDB:pg] is_a: DDPHENO:0001028 ! aberrant filopodium formation [Term] id: DDPHENO:0000465 name: abolished cAMP-induced Ca2+ influx is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000466 name: abolished chemotaxis def: "Complete inability for chemotaxis." [DDB:pg] is_a: DDPHENO:0001122 ! aberrant chemotaxis is_a: DDPHENO:0001131 ! abolished taxis [Term] id: DDPHENO:0000467 name: decreased growth rate in bacterial suspension is_a: DDPHENO:0000202 ! decreased growth rate in suspension [Term] id: DDPHENO:0000471 name: aberrant protein localization def: "Deviation from the normal, usual, or expected location of a protein." [DDB:pg] is_a: DDPHENO:0001009 ! aberrant localization [Term] id: DDPHENO:0000472 name: aberrant regulation of protein modification def: "Deviation from the normal, usual, or expected events during the regulation of protein modification." [DDB:pg] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0000473 name: increased cell polarity def: "Increase in extent, amount, or degree of cell polarity. " [DDB:pg] is_a: DDPHENO:0001029 ! aberrant establishment and/or maintenance of cell polarity [Term] id: DDPHENO:0000474 name: decreased lateral pseudopod formation def: "Reduction in extent, amount, or degree of formation of lateral pseudopod." [DDB:pg] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0000475 name: increased resistance to bisphosphonates is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000476 name: aberrant aggregation during macrocyst formation is_a: DDPHENO:0001010 ! aberrant macrocyst differentiation [Term] id: DDPHENO:0000477 name: decreased lateral pseudopod traction def: "Reduction in extent, amount, or degree of traction of lateral pseudopods." [DDB:pg] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0000478 name: increased lateral pseudopod formation def: "Increase in extent, amount, or degree of formation of lateral pseudopods. " [DDB:pg] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0000479 name: increased sensitivity to DNA-damaging agents is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000480 name: aberrant cAMP signaling def: "Deviation from the normal, usual, or expected events during cAMP signaling." [DDB:pg] comment: child of: GO:0007165 : signal transduction is_a: DDPHENO:0001118 ! aberrant signal transduction [Term] id: DDPHENO:0000481 name: decreased phosphorylation of actin def: "Reduction in extent, amount, or degree of phosphorylation of actin." [DDB:pg] is_a: DDPHENO:0000457 ! aberrant phosphorylation of actin is_a: DDPHENO:0001344 ! decreased protein phosphorylation [Term] id: DDPHENO:0000482 name: aberrant streaming def: "Deviation from the normal, usual, or expected process of streaming." [DDB:pg] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000483 name: aberrant aggregation alt_id: DDPHENO:0000013 alt_id: DDPHENO:0000539 alt_id: DDPHENO:0000541 def: "Deviation from the normal, usual, or expected events during aggregation." [DDB:pg] synonym: "aberrant formation of the aggregation territory" RELATED [] synonym: "agg-" RELATED [] synonym: "aggregation defective" RELATED [] synonym: "merged_aggregation defective" EXACT [] synonym: "merged_aggregation defective at low cell density" EXACT [] synonym: "merged_aggregation defective under submerged conditions" EXACT [] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0000484 name: curly fingers is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000486 name: resistant to spectinomycin is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000487 name: abolished sorting to prestalk region def: "Complete inability for cells to sort to the prestalk region. " [DDB:pg] is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000488 name: delayed response to cAMP def: "Late onset or slower progression in the response to cAMP. " [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000489 name: increased cytosolic Ca2+ response is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0000490 name: decreased extracellular Ca2+ uptake def: "Reduction in extent, amount, or degree of uptake of extracellular calcium." [DDB:pg] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0000491 name: abolished resistance to pathogenic bacteria is_a: DDPHENO:0001193 ! aberrant infection rate by a microorganism [Term] id: DDPHENO:0000492 name: abolished streaming def: "Complete inability for streaming. " [DDB:pg] is_a: DDPHENO:0000482 ! aberrant streaming [Term] id: DDPHENO:0000493 name: abolished CRAC localization to the plasma membrane def: "Complete inability for translocation of CRAC (dagA) from the cytoplasm to the plasma membrane in responsee to a stimulus." [DDB:pg] is_a: DDPHENO:0001387 ! aberrant CRAC localization to the plasma membrane is_a: DDPHENO:0001394 ! abolished localization of protein to the plasma membrane [Term] id: DDPHENO:0000494 name: aberrant adaptation of adenylate cyclase def: "Deviation from the normal, usual, or expected events during the adaptation of adenylate cyclase." [DDB:pg] synonym: "impaired adenylate cyclase adaptation" RELATED [] is_a: DDPHENO:0001262 ! aberrant adaptation of signaling pathway [Term] id: DDPHENO:0000495 name: decreased cytosine methylation in genomic DNA def: "Reduction in extent, amount, or degree of cytosine methylation in genomic DNA." [DDB:pg] is_a: DDPHENO:0001247 ! aberrant protein amino acid methylation [Term] id: DDPHENO:0000496 name: increased growth rate in suspension is_a: DDPHENO:0000171 ! increased growth rate [Term] id: DDPHENO:0000497 name: decreased number of vacuoles def: "Quantitative reduction in vacuoles. " [DDB:pg] is_a: DDPHENO:0001041 ! aberrant vacuole organization and biogenesis [Term] id: DDPHENO:0000498 name: abolished autophagic vacuole formation def: "Complete inability to form autophagic vacuoles." [DDB:pg] is_a: DDPHENO:0000388 ! abolished vacuolation [Term] id: DDPHENO:0000499 name: abolished cell-substrate adhesion def: "Complete inability for cell-substrate adhesion. " [DDB:pg] synonym: "abolished substrate adhesion" RELATED [] is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion [Term] id: DDPHENO:0000500 name: small pinosomes is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000501 name: increased number of pinosomes def: "Quantitative increase in pinosomes. " [DDB:pg] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000503 name: precocious culmination def: "Early onset or faster progression through culmination. " [DDB:pg] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000504 name: decreased sporulation alt_id: DDPHENO:0000194 def: "Reduction in extent, amount, or degree of sporulation." [DDB:pg] synonym: "decreased number of spores" RELATED [] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000509 name: delayed development in the presence of TMB-8 is_a: DDPHENO:0000162 ! delayed development [Term] id: DDPHENO:0000510 name: aberrant stalk morphogenesis def: "Deviation from the normal, usual, or expected events during stalk morphogenesis. " [DDB:pg] is_a: DDPHENO:0000009 ! aberrant fruiting body morphology is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000512 name: abolished prestalk cell differentiation def: "Complete inability for differentiation of prestalk cells." [DDB:pg] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation [Term] id: DDPHENO:0000513 name: aberrant sporulation alt_id: DDPHENO:0000023 def: "Deviation from the normal, usual, or expected events during sporulation." [DDB:pg] synonym: "aberrant spore differentiation" RELATED [] synonym: "defective spore differentiation" RELATED [] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0000514 name: abolished stalk cell differentiation def: "Complete inability for differentiation into stalk cells. " [DDB:pg] is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation [Term] id: DDPHENO:0000516 name: abolished prespore cell differentiation def: "Complete inability for differentiation of prespore cells. " [DDB:pg] is_a: DDPHENO:0001025 ! aberrant prespore cell differentiation [Term] id: DDPHENO:0000517 name: increased sporulation in the presence of 8-Br-cAMP is_a: DDPHENO:0000032 ! increased sporulation [Term] id: DDPHENO:0000518 name: increased stalk width def: "Having a relative thick stalk." [DDB:pg] synonym: "thick stalk" EXACT [] xref: PATO:0000599 is_a: DDPHENO:0000510 ! aberrant stalk morphogenesis [Term] id: DDPHENO:0000519 name: decreased sporulation in the presence of 8-Br-cAMP is_a: DDPHENO:0000504 ! decreased sporulation [Term] id: DDPHENO:0000520 name: abolished stalk cell differentiation in vitro def: "Complete inability for differentiation into stalk cells in vitro. " [DDB:pg] is_a: DDPHENO:0000514 ! abolished stalk cell differentiation [Term] id: DDPHENO:0000521 name: increased sporulation in vitro is_a: DDPHENO:0000032 ! increased sporulation [Term] id: DDPHENO:0000522 name: decreased chemotaxis to cAMP def: "Reduction in extent, amount, or degree of chemotaxis in response to cAMP." [DDB:pg] synonym: " synonym: "decreased positive chemotaxis to cAMP" EXACT [] is_a: DDPHENO:0000099 ! decreased chemotaxis rate is_a: DDPHENO:0001167 ! aberrant chemotaxis to cAMP [Term] id: DDPHENO:0000523 name: decreased chemotaxis to folate def: "Reduction in extent, amount, or degree of chemotaxis in response to folate." [DDB:pg] synonym: "decreased chemotaxis to folic acid" EXACT [] synonym: "decreased positive chemotaxis to folate" EXACT [] synonym: "decreased positive chemotaxis to folic acid" EXACT [] is_a: DDPHENO:0000099 ! decreased chemotaxis rate is_a: DDPHENO:0001168 ! aberrant chemotaxis to folate [Term] id: DDPHENO:0000524 name: increased sorting to prestalk region def: "Increase in extent, amount, or degree of cell sorting to the prestalk region. " [DDB:pg] is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0000525 name: increased cell cycle length is_a: DDPHENO:0001418 ! aberrant cell cycle [Term] id: DDPHENO:0000526 name: increased prestalk cell differentiation in response to DIF-1 def: "Increase in extent, amount, or degree of prestalk cell differentiation in response to DIF-1. " [DDB:pg] is_a: DDPHENO:0000169 ! increased prestalk cell differentiation [Term] id: DDPHENO:0000527 name: abolished histone H3-K4 methylation def: "Complete inability for methylation of histone H3 at lysine 4." [DDB:pg] is_a: DDPHENO:0001248 ! abolished protein amino acid methylation [Term] id: DDPHENO:0000528 name: increased rate of endocytosis def: "Increase in extent, amount, or degree of endocytosis." [DDB:pf] is_a: DDPHENO:0000090 ! aberrant endocytosis [Term] id: DDPHENO:0000529 name: increased stalk cell differentiation def: "Increase in extent, amount, or degree of differentiation into stalk cells. " [DDB:pgg] synonym: "decreased number of stalk cells" EXACT [] is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation [Term] id: DDPHENO:0000530 name: increased gene silencing by RNA interference def: "Increase in extent, amount, or degree of gene silencing by RNA interference." [DDB:pg] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0000533 name: aberrant anaphase def: "Deviation from the normal, usual, or expected events during anaphase." [DDB:pg] is_a: DDPHENO:0000234 ! aberrant mitosis [Term] id: DDPHENO:0000534 name: decreased growth rate in suspension at low temperature is_a: DDPHENO:0000202 ! decreased growth rate in suspension [Term] id: DDPHENO:0000535 name: decreased intracellular glycogen level def: "Reduction in amount or accumulation of intracellular glycogen." [DDB:pg] synonym: "decreased cytosolic glycogen level" RELATED [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000536 name: increased intracellular glutamate level def: "Increase in amount or accumulation of intracellular glutamate." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000537 name: increased extracellular ammonia level def: "Increase in amount or accumulation of extracellular ammonia." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000538 name: decreased intracellular pteridine level def: "Reduction in amount or accumulation of intracellular pteridine." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000540 name: increased pseudopod size def: "Increase in relative or proportionate dimensions of the pseudopod. " [DDB:pg] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0000542 name: increased infection rate by Legionella pneumophila def: "Increase in extent, amount, or degree of the infection rate by Legionella pneumophila." [DDB:pf] synonym: "increased sensitivity to infection by Legionella pneumophila" RELATED [] is_a: DDPHENO:0001194 ! increased infection rate by a microorganism [Term] id: DDPHENO:0000543 name: increased infection rate by Mycobacterium avium def: "Increase in extent, amount, or degree of the infection rate by Mycobacterium avium." [DDB:pf] synonym: "increased sensitivity to infection by Mycobacterium avium" RELATED [] is_a: DDPHENO:0001194 ! increased infection rate by a microorganism [Term] id: DDPHENO:0000544 name: abolished iron ion transport def: "Complete inability to transport iron. " [DDB:pg] is_a: DDPHENO:0001026 ! aberrant ion transport [Term] id: DDPHENO:0000545 name: increased iron ion transport def: "Increase in extent, amount, or degree of transport of iron. " [DDB:pg] is_a: DDPHENO:0001026 ! aberrant ion transport [Term] id: DDPHENO:0000546 name: aberrant stalk cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of stalk cells." [DDB:pg] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0000547 name: aberrant culminant morphology def: "Deviation from the normal, usual, or expected morphology of the culminant." [DDB:pg] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000549 name: decreased stalk width def: "Having a relative thin stalk." [DDB:pg] synonym: "thin stalk" EXACT [] xref: PATO:0000600 is_a: DDPHENO:0000510 ! aberrant stalk morphogenesis [Term] id: DDPHENO:0000550 name: abolished pinocytosis def: "Complete inability for phagocytosis. " [DDB:pg] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000551 name: increased pseudopod formation def: "Increase in extent, amount, or degree of formation of pseudopods. " [DDB:pg] synonym: "increased pseudopod extension" EXACT [] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0001001 name: aberrant initiation of development def: "Deviation from the normal, usual, or expected during the initiation of development." [DDB:pg] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0001002 name: aberrant organelle morphology def: "Deviation from the normal, usual, or expected morphology of organelles." [DDB:pg] comment: child of GO:0006996 : organelle organization and biogenesis is_a: DDPHENO:0001043 ! aberrant organelle organization and biogenesis [Term] id: DDPHENO:0001003 name: aberrant response to stimulus def: "Deviation from the normal, usual, or expected events during the response to stimulus." [DDB:pg] comment: child of GO:0050896 : response to stimulus is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0001004 name: aberrant cellular physiological process def: "OBSOLETE. Deviation from the normal, usual, or expected events during cellular physiological processes. " [DDB:pg] comment: child of GO:0050875 : cellular physiological process. Obsoleted becasue GO merged with cellular process. All children were moved under DDPHENO:0001008 aberrant cellular process is_obsolete: true [Term] id: DDPHENO:0001005 name: aberrant cellular metabolic process def: "Deviation from the normal, usual, or expected events during cellular metabolism." [DDB:pg] comment: child of GO:0044237: cellular metabolism. synonym: "aberrant cellular metabolism" EXACT [] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001006 name: aberrant phagocytosis def: "Deviation from the normal, usual, or expected events during phagocytosis." [DDB:pg] comment: child of GO:0006909 : phagocytosis is_a: DDPHENO:0000090 ! aberrant endocytosis [Term] id: DDPHENO:0001007 name: aberrant pinocytosis def: "Deviation from the normal, usual, or expected events during pinocytosis. " [DDB:pg] comment: child of GO:0006907 : pinocytosis is_a: DDPHENO:0000090 ! aberrant endocytosis [Term] id: DDPHENO:0001008 name: aberrant cellular process def: "Deviation from the normal, usual, or expected events during cellular processes." [DDB:pg] comment: child of GO:0009987 : cellular process is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0001009 name: aberrant localization def: "Deviation from the normal, usual, or expected events during localization." [DDB:pg] is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0001010 name: aberrant macrocyst differentiation def: "Deviation from the normal, usual, or expected events during formation of macrocysts." [DDB:pg] comment: child of GO:0000747: conjugation with cellular fusion synonym: "aberrant conjugation with cellular fusion" EXACT [] synonym: "aberrant macrocyst formation" EXACT [] synonym: "aberrant sexual reproduction" BROAD [] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001011 name: decreased intracellular cAMP level def: "Reduction in amount or accumulation of intracellular cAMP." [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0001012 name: aberrant stalk formation def: "Deviation from the normal, usual, or expected events during stalk formation." [DDB:pg] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0001013 name: aberrant cell differentiation def: "Deviation from the normal, usual, or expected events during cell differentiation." [DDB:pg] is_a: DDPHENO:0000154 ! aberrant development is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001014 name: aberrant slug formation def: "Deviation from the normal, usual, or expected events during slug formation." [DDB:pg] synonym: "pseudoplasmodium formation" EXACT [] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0001015 name: aberrant culmination def: "Deviation from the normal, usual, or expected events during culmination." [DDB:pg] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0001016 name: aberrant regulation of fruiting body formation def: "Deviation from the normal, usual, or expected events during the regulation of fruiting body formation." [DDB:pg] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0001017 name: aberrant regulation of aggregate size def: "Deviation from the normal, usual, or expected events during the regulation of aggregate size." [DDB:pg] synonym: "regulation of aggregation during fruiting body formation" RELATED [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0001020 name: aberrant regulation of stalk cell differentiation def: "Deviation from the normal, usual, or expected events during the regulation of stalk cell differentiation. " [DDB:pg] is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation [Term] id: DDPHENO:0001021 name: aberrant negative regulation of stalk cell differentiation def: "Deviation from the normal, usual, or expected events during negative regulation of stalk cell differentiation. " [DDB:pg] is_a: DDPHENO:0001020 ! aberrant regulation of stalk cell differentiation [Term] id: DDPHENO:0001022 name: aberrant positive regulation of stalk cell differentiation def: "Deviation from the normal, usual, or expected events during positive regulation of stalk cell differentiation. " [DDB:pg] is_a: DDPHENO:0001020 ! aberrant regulation of stalk cell differentiation [Term] id: DDPHENO:0001023 name: aberrant prestalk cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prestalk cells." [DDB:pg] synonym: "aberrant pst cell differentiation" EXACT [] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001024 name: aberrant prestalk O cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prestalk O cells. " [DDB:pg] synonym: "aberrant pstO cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation [Term] id: DDPHENO:0001025 name: aberrant prespore cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prespore cells." [DDB:pg] synonym: "aberrant psp cell differentiation" EXACT [] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001026 name: aberrant ion transport def: "Deviation from the normal, usual, or expected events during ion transport. " [DDB:pg] is_a: DDPHENO:0001047 ! aberrant transport [Term] id: DDPHENO:0001027 name: aberrant pseudopod formation def: "Deviation from the normal, usual, or expected events during pseudopod formation." [DDB:pg] is_a: DDPHENO:0001048 ! aberrant cell projection biogenesis [Term] id: DDPHENO:0001028 name: aberrant filopodium formation def: "Deviation from the normal, usual, or expected events during filopodium formation. " [DDB:pg] is_a: DDPHENO:0001048 ! aberrant cell projection biogenesis [Term] id: DDPHENO:0001029 name: aberrant establishment and/or maintenance of cell polarity def: "Deviation from the normal, usual, or expected events during establishment and/or maintenance of cell polarity." [DDB:pg] is_a: DDPHENO:0000236 ! aberrant cell morphology [Term] id: DDPHENO:0001030 name: aberrant protein secretion alt_id: DDPHENO:0000186 def: "Deviation from the normal, usual, or expected events during protein secretion." [DDB:pg] synonym: "aberrant lysosomal traffic" EXACT [] is_a: DDPHENO:0000471 ! aberrant protein localization is_a: DDPHENO:0001043 ! aberrant organelle organization and biogenesis [Term] id: DDPHENO:0001031 name: aberrant response to abiotic stimulus def: "Deviation from the normal, usual, or expected events during the response to abiotic stimulus." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001032 name: aberrant response to biotic stimulus def: "Deviation from the normal, usual, or expected events during the response to biotic stimulus. " [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001033 name: aberrant macrocyst morphology def: "Deviation from the normal, usual, or expected morphology of the macrocyst. " [DDB:pg] is_a: DDPHENO:0000236 ! aberrant cell morphology [Term] id: DDPHENO:0001034 name: aberrant response to stress def: "Deviation from the normal, usual, or expected events during the response to stress." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001035 name: aberrant response to heat def: "Deviation from the normal, usual, or expected events during the response to heat. " [DDB:pg] is_a: DDPHENO:0001034 ! aberrant response to stress [Term] id: DDPHENO:0001036 name: aberrant response to oxidative stress def: "Deviation from the normal, usual, or expected events during the response to oxidative stress. " [DDB:pg] is_a: DDPHENO:0001034 ! aberrant response to stress [Term] id: DDPHENO:0001037 name: aberrant signal transduction during aggregation def: "Deviation from the normal, usual, or expected events during signal transduction during development. " [DDB:pg] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0001038 name: aberrant cAMP signaling during aggregation alt_id: DDPHENO:0000419 alt_id: DDPHENO:0000468 alt_id: DDPHENO:0000469 def: "Deviation from the normal, usual, or expected events during cAMP signaling during aggregation." [DDB:pg] comment: Merged with aberrant cAMP signaling during aggregation. PG 10-24-2006 synonym: "merged_aggregation hypersensitive to caffeine" EXACT [] synonym: "merged_aggregation resistant to caffeine" EXACT [] synonym: "merged_impaired cAMP signaling in the presence of gossypol" EXACT [] is_a: DDPHENO:0000480 ! aberrant cAMP signaling is_a: DDPHENO:0001037 ! aberrant signal transduction during aggregation [Term] id: DDPHENO:0001039 name: aberrant response to starvation def: "Deviation from the normal, usual, or expected events during the response to starvation. " [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001040 name: obsolete_aberrant response to drug def: "OBSOLETE. Deviation from the normal, usual, or expected events during the response to drug. " [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001041 name: aberrant vacuole organization and biogenesis def: "Deviation from the normal, usual, or expected process of vacuole organization and biogenesis." [DDB:pg] is_a: DDPHENO:0001043 ! aberrant organelle organization and biogenesis [Term] id: DDPHENO:0001042 name: aberrant cell organization and biogenesis def: "Deviation from the normal, usual, or expected events during cell organization and biogenesis." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001043 name: aberrant organelle organization and biogenesis def: "Deviation from the normal, usual, or expected events during organelle organization and biogenesis." [DDB:pg] is_a: DDPHENO:0001042 ! aberrant cell organization and biogenesis [Term] id: DDPHENO:0001044 name: aberrant cell adhesion def: "Deviation from the normal, usual, or expected events during cell adhesion." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001045 name: aberrant response to DNA damaging agents def: "Deviation from the normal, usual, or expected events during the response to DNA damaging agents." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001046 name: aberrant spore germination def: "Deviation from the normal, usual, or expected events during spore germination." [DDB:pg] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001047 name: aberrant transport def: "Deviation from the normal, usual, or expected events during transport. " [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001048 name: aberrant cell projection biogenesis def: "Deviation from the normal, usual, or expected events during cell projection biogenesis." [DDB:pg] is_a: DDPHENO:0001042 ! aberrant cell organization and biogenesis [Term] id: DDPHENO:0001049 name: aberrant bleb formation def: "Deviation from the normal, usual, or expected events during bleb formation." [DDB:pg] synonym: "aberrant cell blebbing" RELATED [] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001050 name: abolished bleb formation def: "Complete inability to form blebs. " [DDB:pg] synonym: "abolished cell blebbing" RELATED [] is_a: DDPHENO:0001049 ! aberrant bleb formation [Term] id: DDPHENO:0001051 name: abolished chemotaxis during aggregation def: "Complete inability for chemotaxis during aggregation. " [DDB:pg] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0001052 name: decreased bleb formation def: "Reduction in extent, amount, or degree of bleb formation. " [DDB:pg] synonym: "decreased cell blebbing" RELATED [] is_a: DDPHENO:0001049 ! aberrant bleb formation [Term] id: DDPHENO:0001053 name: increased bleb formation def: "Increase in extent, amount, or degree of bleb formation. " [DDB:pg] synonym: "increased cell blebbing" RELATED [] is_a: DDPHENO:0001049 ! aberrant bleb formation [Term] id: DDPHENO:0001054 name: multiple tips in culminant is_a: DDPHENO:0000036 ! multiple tips [Term] id: DDPHENO:0001055 name: multiple tips in mound is_a: DDPHENO:0000036 ! multiple tips [Term] id: DDPHENO:0001056 name: decreased F-actin polymerization def: "Reduction in extent, amount, or degree of F-actin polymerization. " [DDB:pg] is_a: DDPHENO:0001445 ! aberrant F-actin polymerization [Term] id: DDPHENO:0001057 name: abolished F-actin polymerization def: "Complete inability to polymerize actin into F-actin." [DDB:pg] is_a: DDPHENO:0001445 ! aberrant F-actin polymerization [Term] id: DDPHENO:0001058 name: decreased protein kinase activation def: "Reduction in extent, amount, or degree of activation of a protein kinase." [DDB:pg] is_a: DDPHENO:0001119 ! aberrant regulation of protein kinase activity [Term] id: DDPHENO:0001059 name: abolished chemotaxis to cAMP during aggregation def: "Complete inability for chemotaxis to cAMP during aggregation. " [DDB:pg] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0001061 name: increased protein kinase activation def: "Increase in extent, amount, or degree of activation of protein kinases. " [DDB:pg] is_a: DDPHENO:0001119 ! aberrant regulation of protein kinase activity [Term] id: DDPHENO:0001062 name: abolished protein kinase activation def: "Complete inability for activation of protein kinases." [DDB:pg] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process is_a: DDPHENO:0001119 ! aberrant regulation of protein kinase activity [Term] id: DDPHENO:0001063 name: abolished myosin light chain kinase activation def: "Complete inability for activation of myosin light chain kinase upon stimulus." [DDB:pg] is_a: DDPHENO:0001062 ! abolished protein kinase activation [Term] id: DDPHENO:0001064 name: decreased myosin light chain kinase activation def: "Reduction in extent, amount, or degree of activation of myosin light chain kinase. " [DDB:pg] is_a: DDPHENO:0001058 ! decreased protein kinase activation [Term] id: DDPHENO:0001065 name: increased myosin light chain kinase activation def: "Increase in extent, amount, or degree of activation of myosin light chain kinase. " [DDB:pg] is_a: DDPHENO:0001061 ! increased protein kinase activation [Term] id: DDPHENO:0001066 name: aberrant contractile vacuole morphology def: "Deviation from the normal, usual, or expected morphology of the vacuole." [DDB:pg] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0001067 name: aberrant response to hyperosmotic stress def: "Deviation from the normal, usual, or expected events during the response to hyperosmotic stress." [DDB:pg] synonym: "aberrant response to hypertonic stress" EXACT [] is_a: DDPHENO:0000209 ! aberrant response to osmotic stress [Term] id: DDPHENO:0001068 name: aberrant response to hypo-osmotic stress def: "Deviation from the normal, usual, or expected events during the response to hypo-osmotic stress." [DDB:pg] synonym: "aberrant response to hypotonic stress" EXACT [] is_a: DDPHENO:0000209 ! aberrant response to osmotic stress [Term] id: DDPHENO:0001069 name: delayed response to hyperosmotic stress def: "Late onset or slower progression in the response to hyperosmotic stress." [DDB:pg] is_a: DDPHENO:0001067 ! aberrant response to hyperosmotic stress [Term] id: DDPHENO:0001070 name: precocious response to hyperosmotic stress def: "Early onset or faster progression in the response to hyperosmotic stress." [DDB:pg] is_a: DDPHENO:0001067 ! aberrant response to hyperosmotic stress [Term] id: DDPHENO:0001071 name: precocious response to hypo-osmotic stress def: "Early onset or faster progression in the response to hypo-osmotic stress." [DDB:pg] is_a: DDPHENO:0001068 ! aberrant response to hypo-osmotic stress [Term] id: DDPHENO:0001072 name: delayed response to hypo-osmotic stress def: "Late onset or slower progression in the response to hypo-osmotic stress." [DDB:pg] is_a: DDPHENO:0001068 ! aberrant response to hypo-osmotic stress [Term] id: DDPHENO:0001074 name: aberrant osmosensory signaling pathway def: "Deviation from the normal, usual, or expected events during the osmosensory signaling pathway" [DDB:pg] is_a: DDPHENO:0001067 ! aberrant response to hyperosmotic stress [Term] id: DDPHENO:0001075 name: decreased prestalk A cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prestalk A cells. " [DDB:pg] synonym: "decreased number of prestalk A cells" RELATED [] synonym: "decreased pstA cell differentiation" EXACT [] is_a: DDPHENO:0000098 ! aberrant prestalk A cell differentiation is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation [Term] id: DDPHENO:0001076 name: abolished prestalk A cell differentation def: "Complete inability for differentiation of prestalk A cells. " [DDB:pg] synonym: "abolished pstA cell differentation" EXACT [] is_a: DDPHENO:0000098 ! aberrant prestalk A cell differentiation is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation [Term] id: DDPHENO:0001077 name: aberrant slug migration def: "Deviation from the normal, usual, or expected events during slug migration." [DDB:kp] is_a: DDPHENO:0001014 ! aberrant slug formation [Term] id: DDPHENO:0001078 name: aberrant mitochondrion morphology def: "Deviation from the normal, usual, or expected morphology of the mitochondrion." [DDB:pg] synonym: "aberrant mitochondrial morphology" EXACT [] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0001079 name: decreased number of tubular mitochondria def: "Quantitative decrease in tubular mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular. " [DDB:pg, PMID:14665465] is_a: DDPHENO:0000271 ! decreased number of mitochondria [Term] id: DDPHENO:0001080 name: abolished aggregation def: "Complete inability for aggregation" [DDB:pg] synonym: "agg-" RELATED [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0001081 name: decreased number of spherical mitochondria def: "Quantitative decrease in spherical mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular. \n" [DDB:pg, PMID:14665465] is_a: DDPHENO:0000271 ! decreased number of mitochondria [Term] id: DDPHENO:0001082 name: increased number of spherical mitochondria def: "Quantitative increase in spherical mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg, PMID:14665465] is_a: DDPHENO:0000272 ! increased number of mitochondria [Term] id: DDPHENO:0001083 name: decreased number of rod-shaped mitochondria def: "Quantitative decrease in rod-shaped mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg, PMID:14665465] is_a: DDPHENO:0000271 ! decreased number of mitochondria [Term] id: DDPHENO:0001084 name: aberrant vegetative growth def: "Deviation from the normal, usual, or expected events during vegetative growth." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001085 name: increased number of rod-shaped mitochondria def: "Quantitative increase in rod-shaped mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg, PMID:14665465] is_a: DDPHENO:0000272 ! increased number of mitochondria [Term] id: DDPHENO:0001086 name: increased chemotaxis to cAMP def: "Increase in extent, amount, or degree of chemotaxis in response to cAMP." [DDB:pf] synonym: "increased positive chemotaxis to cAMP" EXACT [] is_a: DDPHENO:0000400 ! increased chemotaxis rate is_a: DDPHENO:0001167 ! aberrant chemotaxis to cAMP [Term] id: DDPHENO:0001087 name: increased chemotaxis to folate def: "Increase in extent, amount, or degree of chemotaxis in response to folate." [DDB:pf] synonym: "increased chemotaxis to folic acid" EXACT [] synonym: "increased positive chemotaxis to folate" EXACT [] synonym: "increased positive chemotaxis to folic acid" EXACT [] is_a: DDPHENO:0000400 ! increased chemotaxis rate is_a: DDPHENO:0001168 ! aberrant chemotaxis to folate [Term] id: DDPHENO:0001088 name: aberrant response to DIF def: "Deviation from the normal, usual, or expected during the response to differentiation inducing factor" [DDB:pg] synonym: "aberrant response to DIF-1" NARROW [] synonym: "aberrant response to differentiation inducing factor" EXACT [] is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus [Term] id: DDPHENO:0001090 name: decreased response to DIF def: "Reduction in extent, amount, or degree of response to DIF." [DDB:pg] synonym: "decreased response to DIF-1" NARROW [] synonym: "decreased response to differentiation inducing factor" EXACT [] is_a: DDPHENO:0001088 ! aberrant response to DIF [Term] id: DDPHENO:0001091 name: increased response to DIF def: "Increase in extent, amount, or degree of response to DIF." [DDB:pg] synonym: "increased response to DIF-1" NARROW [] synonym: "increased response to differentiation inducing factor" EXACT [] is_a: DDPHENO:0001088 ! aberrant response to DIF [Term] id: DDPHENO:0001092 name: abolished response to DIF def: "Complete inability for response to DIF." [DDB:pg] synonym: "abolished response to DIF-1" NARROW [] synonym: "abolished response to differentiation inducing factor" EXACT [] is_a: DDPHENO:0001088 ! aberrant response to DIF [Term] id: DDPHENO:0001093 name: delayed response to DIF def: "Late onset or slower progression in the response to DIF. " [DDB:pg] synonym: "delayed response to DIF-1" NARROW [] synonym: "delayed response to differentiation inducing factor" EXACT [] is_a: DDPHENO:0001088 ! aberrant response to DIF [Term] id: DDPHENO:0001094 name: precocious response to DIF def: "Early onset or faster progression in the response to DIF." [DDB:pg] synonym: "precocious response to DIF-1" NARROW [] synonym: "precocious response to differentiation inducing factor" EXACT [] is_a: DDPHENO:0001088 ! aberrant response to DIF [Term] id: DDPHENO:0001095 name: aberrant DIF production def: "Deviation from the normal, usual, or expected in the production of DIF." [DDB:pg] synonym: "aberrant DIF-1 production" NARROW [] synonym: "aberrant differentiation inducing factor production" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001096 name: decreased growth rates on solid surfaces is_a: DDPHENO:0000394 ! decreased growth rate [Term] id: DDPHENO:0001097 name: decreased DIF production def: "Reduction in extent, amount, or degree of production of DIF." [DDB:pg] synonym: "decreased DIF-1 production" NARROW [] synonym: "decreased differentiation inducing factor production" EXACT [] is_a: DDPHENO:0001095 ! aberrant DIF production [Term] id: DDPHENO:0001098 name: increased DIF production def: "Increase in extent, amount, or degree of DIF production." [DDB:pg] synonym: "increased DIF-1 production" NARROW [] synonym: "increased differentiation inducing factor production" EXACT [] is_a: DDPHENO:0001095 ! aberrant DIF production [Term] id: DDPHENO:0001099 name: delayed DIF production def: "Late onset or slower progression in the production of DIF. " [DDB:pg] synonym: "delayed DIF-1 production" NARROW [] synonym: "delayed differentiation inducing factor production" EXACT [] is_a: DDPHENO:0001095 ! aberrant DIF production [Term] id: DDPHENO:0001100 name: precocious DIF production def: "Early onset or faster progression in the production of DIF. " [DDB:pg] synonym: "precocious DIF-1 production" NARROW [] synonym: "precocious differentiation inducing factor production" EXACT [] is_a: DDPHENO:0001095 ! aberrant DIF production [Term] id: DDPHENO:0001101 name: abolished chemotaxis to cAMP def: "Complete inability for chemotaxis in response to cAMP." [DDB:pf] synonym: "abolished positive chemotaxis to cAMP" EXACT [] is_a: DDPHENO:0000466 ! abolished chemotaxis is_a: DDPHENO:0001167 ! aberrant chemotaxis to cAMP [Term] id: DDPHENO:0001102 name: abolished chemotaxis to folate def: "Complete inability for chemotaxis in response to folate." [DDB:pf] synonym: "abolished chemotaxis to folic acid" EXACT [DDB:kp] synonym: "abolished positive chemotaxis to folate" RELATED [] synonym: "abolished positive chemotaxis to folic acid" EXACT [] is_a: DDPHENO:0000466 ! abolished chemotaxis is_a: DDPHENO:0001168 ! aberrant chemotaxis to folate [Term] id: DDPHENO:0001103 name: decreased culmination def: "Reduction in extent, amount, or degree of culminants, resulting in fewer fruiting bodies." [DDB:pf] synonym: "decreased number of fruiting bodies" EXACT [] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0001104 name: increased culmination def: "Increase in extent, amount, or degree of culminants, resulting in fewer fruiting bodies." [DDB:pf] synonym: "increased number of fruiting bodies" RELATED [] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0001105 name: aberrant catalytic activity def: "Deviation from the normal, usual, or expected activity of a catalyst." [DDB:pf] synonym: "aberrant enzyme activity" NARROW [DDB:kp] is_a: DDPHENO:0001171 ! aberrant molecular function [Term] id: DDPHENO:0001106 name: decreased lysosomal enzyme activity def: "Reduction in extent, amount, or degree of activity of lysosomal enzyme." [DDB:pf] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001107 name: increased lysosomal enzyme activity def: "Increase in extent, amount, or degree of activity of lysosomal enzyme." [DDB:pf] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001108 name: aberrant response to lithium def: "Deviation from the normal, usual, or expected events during the response to lithium" [DDB:pf] is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus [Term] id: DDPHENO:0001109 name: aberrant response to valproic acid def: "Deviation from the normal, usual, or expected events during the response to valproic acid" [DDB:pf] synonym: "aberrant response to VPA" RELATED [] is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus [Term] id: DDPHENO:0001110 name: aberrant exocytosis def: "Deviation from the normal, usual, or expected events during exocytosis." [DDB:pf] is_a: DDPHENO:0001047 ! aberrant transport [Term] id: DDPHENO:0001111 name: decreased exocytosis def: "Reduction in extent, amount, or degree of exocytosis." [DDB:pf] is_a: DDPHENO:0001110 ! aberrant exocytosis [Term] id: DDPHENO:0001112 name: increased exocytosis def: "Increase in extent, amount, or degree of exocytosis." [DDB:pf] is_a: DDPHENO:0001110 ! aberrant exocytosis [Term] id: DDPHENO:0001113 name: aberrant gene expression alt_id: DDPHENO:0001000 alt_id: DDPHENO:0001089 def: "Deviation from the normal, usual, or expected expression of genes." [DDB:kp] synonym: "aberrant expression of post aggregation-specific genes" EXACT [] synonym: "merged_aberrant expression of aggregation genes" NARROW [DDB:kp] synonym: "merged_aberrant expression of post-aggregative genes" NARROW [DDB:kp] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001114 name: abolished gene expression alt_id: DDPHENO:0000299 alt_id: DDPHENO:0000515 def: "Complete inability for expression of genes." [DDB:kp] synonym: "merged_abolished expression of post-aggregative genes" NARROW [DDB:kp] synonym: "merged_abolished expression of prespore genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0001115 name: delayed gene expression alt_id: DDPHENO:0000179 alt_id: DDPHENO:0000268 alt_id: DDPHENO:0000470 alt_id: DDPHENO:0000485 def: "Late onset or slower progression in the expression of genes." [DDB:kp] synonym: "merged_delayed expression of aggregation genes" NARROW [DDB:kp] synonym: "merged_delayed expression of post-aggregative genes" NARROW [DDB:kp] synonym: "merged_delayed expression of prespore genes" NARROW [DDB:kp] synonym: "merged_delayed expression of prestalk genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0001116 name: precocious gene expression alt_id: DDPHENO:0000180 alt_id: DDPHENO:0000217 alt_id: DDPHENO:0000218 alt_id: DDPHENO:0001073 def: "Early onset or faster progression in the expression of genes." [DDB:kp] synonym: "merged_precocious expression of aggregation genes" NARROW [DDB:kp] synonym: "merged_precocious expression of post-aggregative genes" NARROW [DDB:kp] synonym: "merged_precocious expression of prespore genes" NARROW [DDB:kp] synonym: "merged_precocious expression of prestalk genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0001117 name: mislocalized gene expression alt_id: DDPHENO:0000182 alt_id: DDPHENO:0000219 def: "Gene expression occurring in an abnormal position or in an unusual manner or form." [DDB:kp] synonym: "aberrant localization of gene expression" EXACT [] synonym: "aberrant localization of psp genes" NARROW [] synonym: "aberrant localization of pst genes" NARROW [] synonym: "ectopic gene expression" EXACT [] synonym: "merged_aberrant localization of prespore genes" NARROW [DDB:kp] synonym: "merged_aberrant localization of prestalk genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0001118 name: aberrant signal transduction def: "Deviation from the normal, usual, or expected events during signal transduction." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001119 name: aberrant regulation of protein kinase activity def: "Deviation from the normal, usual, or expected events during the regulation of protein kinase activity." [DDB:pg] is_a: DDPHENO:0001303 ! aberrant regulation of catalytic activity [Term] id: DDPHENO:0001120 name: abolished protein kinase B activation def: "Complete inability for activation of protein kinase B." [DDB:pg] is_a: DDPHENO:0001062 ! abolished protein kinase activation [Term] id: DDPHENO:0001121 name: aberrant taxis def: "Deviation from the normal, usual, or expected events during the response to an exteral stimulus." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001122 name: aberrant chemotaxis def: "Deviation from the normal, usual, or expected events during the locomotory response to a chemical concentration gradient." [DD:pg] is_a: DDPHENO:0000264 ! aberrant cell motility is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0001123 name: increased phototaxis def: "Increase in extent, amount, or degree of phototaxis." [DDB:pg] is_a: DDPHENO:0000222 ! aberrant phototaxis is_a: DDPHENO:0001129 ! increased taxis [Term] id: DDPHENO:0001124 name: increased thermotaxis def: "Increase in extent, amount, or degree of thermotaxis." [DDB:pg] is_a: DDPHENO:0000223 ! aberrant thermotaxis is_a: DDPHENO:0001129 ! increased taxis [Term] id: DDPHENO:0001125 name: abolished phototaxis def: "Complete inability for phototaxis." [DDB:pg] is_a: DDPHENO:0000222 ! aberrant phototaxis is_a: DDPHENO:0001131 ! abolished taxis [Term] id: DDPHENO:0001126 name: abolished thermotaxis def: "Complete inability for thermotaxis." [DDB:pg] is_a: DDPHENO:0000223 ! aberrant thermotaxis is_a: DDPHENO:0001131 ! abolished taxis [Term] id: DDPHENO:0001127 name: decreased phototaxis def: "Reduction in extent, amount, or degree of phototaxis. " [DDB:pg] is_a: DDPHENO:0000222 ! aberrant phototaxis is_a: DDPHENO:0001130 ! decreased taxis [Term] id: DDPHENO:0001128 name: decreased thermotaxis def: "Reduction in extent, amount, or degree of thermotaxis. " [DDB:pg] is_a: DDPHENO:0000223 ! aberrant thermotaxis is_a: DDPHENO:0001130 ! decreased taxis [Term] id: DDPHENO:0001129 name: increased taxis def: "Increase in extent, amount, or degree of the response to an external stimulus. " [DDB:pg] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0001130 name: decreased taxis def: "Reduction in extent, amount, or degree of the response to external stimulus. " [DDB:pg] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0001131 name: abolished taxis def: "Complete inability to respond to an external stimulus. " [DDB:pg] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0001132 name: decreased activation of adenylate cyclase def: "Reduction in extent, amount, or degree of activation of adenylate cyclase." [DDB:pg] synonym: "decreased activation of ACA" EXACT [] synonym: "defective in activation of adenylate cyclase (ACA)" RELATED [] is_a: DDPHENO:0000198 ! aberrant activation of adenylate cyclase activity [Term] id: DDPHENO:0001133 name: abolished activation of adenylate cyclase def: "Complete inability to activate adenylate cyclase upon stimulus." [DDB:pg] synonym: "abolished activation of ACA" EXACT [] synonym: "defective in activation of adenylate cyclase (ACA)" RELATED [] is_a: DDPHENO:0000198 ! aberrant activation of adenylate cyclase activity [Term] id: DDPHENO:0001134 name: increased activation of adenylate cyclase def: "Increase in extent, amount, or degree of activation of adenylate cyclase." [DDB:pg] synonym: "increased activation of ACA" EXACT [] is_a: DDPHENO:0000198 ! aberrant activation of adenylate cyclase activity [Term] id: DDPHENO:0001135 name: abolished chemoattractant-mediated F-actin polymerization def: "Complete inability for F-actin polymerization in response to chemoattractants." [DDB:pg] is_a: DDPHENO:0000151 ! aberrant F-actin organization [Term] id: DDPHENO:0001136 name: increased chemoattractant-mediated F-actin polymerization def: "Increased in extent, amount, or degree of F-actin polymerization in response to chemoattractants." [DDB:pg] is_a: DDPHENO:0000151 ! aberrant F-actin organization [Term] id: DDPHENO:0001137 name: aberrant regulation of GTPase activity def: "Deviation from the normal, usual, or expected events during the regulation of the activity of a GTPase." [DDB:pg] is_a: DDPHENO:0001303 ! aberrant regulation of catalytic activity [Term] id: DDPHENO:0001138 name: decreased positive regulation of GTPase activity def: "Reduction in extent, amount, or degree of positive regulation of GTPase activity." [DDB:pg] is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity [Term] id: DDPHENO:0001139 name: increased positive regulation of GTPase activity def: "Increase in extent, amount, or degree of positive regulation of GTPase activity." [DDB:pg] is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity [Term] id: DDPHENO:0001140 name: aberrant regulation of Ras GTPase activity def: "Deviation from the normal, usual, or expected events during the regulation of the activity of a Ras GTPase." [DDB:pg] is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity [Term] id: DDPHENO:0001141 name: aberrant regulation of Rac GTPase activity def: "Deviation from the normal, usual, or expected events during the regulation of the activity of a Rac GTPase." [DDB:pg] is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity [Term] id: DDPHENO:0001142 name: aberrant regulation of Rab GTPase activity def: "Deviation from the normal, usual, or expected events during the regulation of the activity of a Rab GTPase." [DDB:pg] is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity [Term] id: DDPHENO:0001143 name: aberrant regulation of Ran GTPase activity def: "Deviation from the normal, usual, or expected events during the regulation of the activity of a Ran GTPase." [DDB:pg] is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity [Term] id: DDPHENO:0001144 name: aberrant regulation of Rap GTPase activity def: "Deviation from the normal, usual, or expected events during the regulation of the activity of a Rap GTPase." [DDB:pg] is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity [Term] id: DDPHENO:0001145 name: decreased positive regulation of Rab GTPase activity def: "Reduction in extent, amount, or degree of positive regulation of Rab GTPase activity." [DDB:pg] is_a: DDPHENO:0001138 ! decreased positive regulation of GTPase activity is_a: DDPHENO:0001142 ! aberrant regulation of Rab GTPase activity [Term] id: DDPHENO:0001146 name: increased positive regulation of Rab GTPase activity def: "Increase in extent, amount, or degree of positive regulation of Rab GTPase activity." [DDB:pg] is_a: DDPHENO:0001139 ! increased positive regulation of GTPase activity is_a: DDPHENO:0001142 ! aberrant regulation of Rab GTPase activity [Term] id: DDPHENO:0001147 name: decreased positive regulation of Rac GTPase activity def: "Reduction in extent, amount, or degree of positive regulation of Rac GTPase activity." [DDB:pg] is_a: DDPHENO:0001138 ! decreased positive regulation of GTPase activity is_a: DDPHENO:0001141 ! aberrant regulation of Rac GTPase activity [Term] id: DDPHENO:0001148 name: increased positive regulation of Rac GTPase activity def: "Increase in extent, amount, or degree of positive regulation of Rac GTPase activity." [DDB:pg] is_a: DDPHENO:0001139 ! increased positive regulation of GTPase activity is_a: DDPHENO:0001141 ! aberrant regulation of Rac GTPase activity [Term] id: DDPHENO:0001149 name: decreased positive regulation of Ran GTPase activity def: "Reduction in extent, amount, or degree of positive regulation of Ran GTPase activity." [DDB:pg] is_a: DDPHENO:0001138 ! decreased positive regulation of GTPase activity is_a: DDPHENO:0001143 ! aberrant regulation of Ran GTPase activity [Term] id: DDPHENO:0001150 name: increased positive regulation of Ran GTPase activity def: "Increase in extent, amount, or degree of positive regulation of Ran GTPase activity." [DDB:pg] is_a: DDPHENO:0001139 ! increased positive regulation of GTPase activity is_a: DDPHENO:0001143 ! aberrant regulation of Ran GTPase activity [Term] id: DDPHENO:0001151 name: decreased positive regulation of Rap GTPase activity def: "Reduction in extent, amount, or degree of positive regulation of Rap GTPase activity." [DDB:pg] is_a: DDPHENO:0001138 ! decreased positive regulation of GTPase activity is_a: DDPHENO:0001144 ! aberrant regulation of Rap GTPase activity [Term] id: DDPHENO:0001152 name: increased positive regulation of Rap GTPase activity def: "Increase in extent, amount, or degree of positive regulation of Rap GTPase activity." [DDB:pg] is_a: DDPHENO:0001139 ! increased positive regulation of GTPase activity is_a: DDPHENO:0001144 ! aberrant regulation of Rap GTPase activity [Term] id: DDPHENO:0001153 name: increased positive regulation of Ras GTPase activity def: "Increase in extent, amount, or degree of positive regulation of Ras GTPase activity." [DDB:pg] is_a: DDPHENO:0001139 ! increased positive regulation of GTPase activity is_a: DDPHENO:0001140 ! aberrant regulation of Ras GTPase activity [Term] id: DDPHENO:0001154 name: decreased positive regulation of Ras GTPase activity def: "Reduction in extent, amount, or degree of positive regulation of Ras GTPase activity." [DDB:pg] is_a: DDPHENO:0001138 ! decreased positive regulation of GTPase activity is_a: DDPHENO:0001140 ! aberrant regulation of Ras GTPase activity [Term] id: DDPHENO:0001155 name: aberrant macromolecule biosynthesis def: "Deviation from the normal, usual, or expected events during macromolecule biosynthesis." [DDB:pg] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001156 name: aberrant cellulose biosynthesis def: "Deviation from the normal, usual, or expected events during cellulose biosynthesis." [DDB:pg] is_a: DDPHENO:0001155 ! aberrant macromolecule biosynthesis [Term] id: DDPHENO:0001157 name: abolished cellulose biosynthesis def: "Complete inability for cellulose biosynthesis." [DDB:pg] is_a: DDPHENO:0001156 ! aberrant cellulose biosynthesis [Term] id: DDPHENO:0001158 name: increased cellulose biosynthesis def: "Increase in extent, amount, or degree of cellulose biosynthesis." [DDB:pg] is_a: DDPHENO:0001156 ! aberrant cellulose biosynthesis [Term] id: DDPHENO:0001159 name: decreased cellulose biosynthesis def: "Reduction in extent, amount, or degree of cellulose biosynthesis." [DDB:pg] is_a: DDPHENO:0001156 ! aberrant cellulose biosynthesis [Term] id: DDPHENO:0001160 name: abolished superoxide production def: "Complete inability for the production of superoxide" [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001161 name: decreased superoxide production def: "Reduction in extent, amount, or degree of production of superoxide" [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001162 name: increased superoxide production def: "Increase in amount or accumulation of superoxide" [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001163 name: aberrant prestalk B cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prestalk B cells" [DDB:pg] synonym: "aberrant pstB cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation [Term] id: DDPHENO:0001164 name: abolished prestalk B cell differentation def: "Complete inability for differentiation of prestalk B cells." [DDB:pg] synonym: "abolished pstB cell differentation" EXACT [] is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation is_a: DDPHENO:0001163 ! aberrant prestalk B cell differentiation [Term] id: DDPHENO:0001165 name: decreased prestalk B cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prestalk B cells" [DDB:pg] synonym: "decreased number of prestalk B cells" RELATED [] synonym: "decreased pstB cell differentiation" EXACT [] is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation is_a: DDPHENO:0001163 ! aberrant prestalk B cell differentiation [Term] id: DDPHENO:0001166 name: increased prestalk B cell differentiation def: "Increase in extent, amount, or degree of differentiation into prestalk B cells." [DDB:pg] synonym: "increased numer of prestalk B cells" RELATED [] synonym: "increased pstB cell differentiation" EXACT [] is_a: DDPHENO:0000169 ! increased prestalk cell differentiation is_a: DDPHENO:0001163 ! aberrant prestalk B cell differentiation [Term] id: DDPHENO:0001167 name: aberrant chemotaxis to cAMP def: "Deviation from the normal, usual, or expected events during the locomotory response to cAMP." [DDB:kp] synonym: "aberrant positive chemotaxis to cAMP" EXACT [] is_a: DDPHENO:0001224 ! aberrant positive chemotaxis [Term] id: DDPHENO:0001168 name: aberrant chemotaxis to folate def: "Deviation from the normal, usual, or expected events during the locomotory response to folate (folic acid)." [DDB:kp] synonym: "aberrant chemotaxis to folic acid" EXACT [DDB:kp] synonym: "aberrant positive chemotaxis to folate" EXACT [] synonym: "aberrant positive chemotaxis to folic acid" EXACT [] is_a: DDPHENO:0001224 ! aberrant positive chemotaxis [Term] id: DDPHENO:0001169 name: delayed cytokinesis def: "Late onset or slower progression through cytokinesis." [DDB:pf] is_a: DDPHENO:0000149 ! aberrant cytokinesis [Term] id: DDPHENO:0001170 name: aberrant cytokinesis, contractile ring contraction def: "Deviation from the normal, usual, or expected events during contractile ring contraction during cytokinesis." [DDB:pf] is_a: DDPHENO:0000149 ! aberrant cytokinesis [Term] id: DDPHENO:0001171 name: aberrant molecular function def: "Deviation from normal, usual, or expected molecular function." [DDB:kp] is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0001172 name: increased Ras guanyl-nucleotide exchange factor activity def: "Increase in extent, amount, or degree of Ras guanyl-nucleotide exchange factor activity." [DDB:kp] synonym: "increased Ras GEF activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001173 name: aberrant aspidocyte differentiation def: "Deviation from the normal, usual, or expected events during formation of aspidocytes." [DDB:pg, PMID:17259634] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001174 name: increased aspidocyte differentiation def: "Increase in extent, amount, or degree of differentiation into aspidocytes. " [DDB:pg, PMID:17259634] is_a: DDPHENO:0001173 ! aberrant aspidocyte differentiation [Term] id: DDPHENO:0001175 name: decreased aspidocyte differentiation def: "Decrease in extent, amount, or degree of differentiation into aspidocytes. " [DDB:pg, PMID:17259634] is_a: DDPHENO:0001173 ! aberrant aspidocyte differentiation [Term] id: DDPHENO:0001176 name: abolished aspidocyte differentiation def: "Complete inability for differentiation of aspidocytes. " [DDB:pg, PMID:17259634] is_a: DDPHENO:0001173 ! aberrant aspidocyte differentiation [Term] id: DDPHENO:0001177 name: decreased pseudopod formation def: "Decrease in extent, amount, or degree of formation of pseudopods. " [DDB:pg] synonym: "decreased pseudopod extension" EXACT [] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0001178 name: decreased pseudopod size def: "Increase in relative or proportionate dimensions of the pseudopod. " [DDB:pg] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0001179 name: decreased F-actin polymerization at the leading edge def: "Reduction in extent, amount, or degree of F-actin polymerization in the area closest to the direction of movement in a motile cell" [DDB:pf] is_a: DDPHENO:0001056 ! decreased F-actin polymerization [Term] id: DDPHENO:0001180 name: increased F-actin polymerization at the leading edge def: "Increase in extent, amount, or degree of F-actin polymerization in the area closest to the direction of movement in a motile cell" [DDB:pf] is_a: DDPHENO:0000459 ! increased F-actin polymerization [Term] id: DDPHENO:0001181 name: delayed pseudopod formation def: "Late onset or slower progression" [DDB:pf] synonym: "delayed pseudopod extension" EXACT [] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0001182 name: decreased spore size def: "Decrease in relative or proportionate dimensions of the spore." [DDB:pg] synonym: "small spores" RELATED [] is_a: DDPHENO:0000163 ! aberrant spore morphology [Term] id: DDPHENO:0001183 name: increased spore size def: "Increase in relative or proportionate dimensions of the spore." [DDB:pg] synonym: "large spores" RELATED [] is_a: DDPHENO:0000163 ! aberrant spore morphology [Term] id: DDPHENO:0001184 name: decreased intracellular myo-inositol level def: "Decrease in amount or accumulation of intracellular myo-inositol." [DDB:pg] synonym: "decreased cytosolic myo-inositol level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001185 name: increased intracellular myo-inositol level def: "Increase in amount or accumulation of intracellular myo-inositol." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001186 name: increased intracellular 2,3-bisphosphoglycerate level def: "Increase in amount or accumulation of intracellular 2,3-bisphosphoglycerate." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001187 name: decreased intracellular 2,3-bisphosphoglycerate level def: "Reduction in amount or accumulation of intracellular 2,3-bisphosphoglycerate." [DDB:pg] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001188 name: abolished macroautophagy def: "Complete inability for macroautophagy." [DDB:pf] is_a: DDPHENO:0000212 ! aberrant macroautophagy [Term] id: DDPHENO:0001189 name: decreased macroautophagy def: "Reduction in extent, amount, or degree of macroautophagy. " [DDB:pf] is_a: DDPHENO:0000212 ! aberrant macroautophagy [Term] id: DDPHENO:0001190 name: increased macroautophagy def: "Increase in extent, amount, or degree of macroautophagy. " [DDB:pf] is_a: DDPHENO:0000212 ! aberrant macroautophagy [Term] id: DDPHENO:0001191 name: increased number of autophagosomes def: "Quantitative increase in autophagosomes." [DDB:pf] synonym: "increased number of autophagic vacuoles" EXACT [] is_a: DDPHENO:0001041 ! aberrant vacuole organization and biogenesis [Term] id: DDPHENO:0001192 name: decreased number of autophagosomes def: "Quantitative reduction in autophagosomes." [DDB:pf] synonym: "decreased number of autophagic vacuoles" EXACT [] is_a: DDPHENO:0001041 ! aberrant vacuole organization and biogenesis [Term] id: DDPHENO:0001193 name: aberrant infection rate by a microorganism def: "Deviation from the normal, usual, or expected events during infection of Dicyostelium by a microorganism." [DDB:pf] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001194 name: increased infection rate by a microorganism def: "Increase in extent, amount, or degree of the infection rate by a microorganism." [DDB:pf] synonym: "increased sensitivity to infection" RELATED [] is_a: DDPHENO:0001193 ! aberrant infection rate by a microorganism [Term] id: DDPHENO:0001195 name: decreased infection rate by a microorganism def: "Reduction in extent, amount, or degree of the infection rate by a microorganism." [DDB:pf] synonym: "increased resistance to infection" RELATED [] is_a: DDPHENO:0001193 ! aberrant infection rate by a microorganism [Term] id: DDPHENO:0001196 name: decreased infection rate by Mycobacterium avium def: "Reduction in extent, amount, or degree of the infection rate by Mycobacterium avium." [DDB:pf] synonym: "increased resistance to infection by Mycobacterium avium" RELATED [] is_a: DDPHENO:0001195 ! decreased infection rate by a microorganism [Term] id: DDPHENO:0001197 name: decreased infection rate by Cryptococcus neoformans def: "Reduction in extent, amount, or degree of the infection rate by Cryptococcus neoformans." [DDB:pf] synonym: "increased resistance to infection by Cryptococcus neoformans" RELATED [] is_a: DDPHENO:0001195 ! decreased infection rate by a microorganism [Term] id: DDPHENO:0001198 name: increased infection rate by Cryptococcus neoformans def: "Increase in extent, amount, or degree of the infection rate by Cryptococcus neoformans." [DDB:pf] synonym: "increased sensitivity to infection by Cryptococcus neoformans" RELATED [] is_a: DDPHENO:0001194 ! increased infection rate by a microorganism [Term] id: DDPHENO:0001199 name: decreased actin-dependent ATPase activity def: "Reduction in extent, amount, or degree of decreased actin-dependent ATPase activity." [DDB:pg] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001200 name: increased actin-dependent ATPase activity def: "Increase in extent, amount, or degree of increased actin-dependent ATPase activity." [DDB:pg] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001201 name: decreased actin filament sliding synonym: "decreased F-actin sliding" EXACT [] is_a: DDPHENO:0000151 ! aberrant F-actin organization [Term] id: DDPHENO:0001202 name: increased actin filament sliding synonym: "increased F-actin sliding" RELATED [] is_a: DDPHENO:0000151 ! aberrant F-actin organization [Term] id: DDPHENO:0001203 name: aberrant response to nutrients def: "Deviation from the normal, usual, or expected events during the response to nutrients." [DDB:pf] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001204 name: increased endosome size def: "Increase in relative or proportionate dimensions of the endosome." [DDB:pg] is_a: DDPHENO:0000230 ! aberrant endosome morphology [Term] id: DDPHENO:0001205 name: decreased endosome size def: "Decrease in relative or proportionate dimensions of the endosome." [DDB:pg] is_a: DDPHENO:0000230 ! aberrant endosome morphology [Term] id: DDPHENO:0001206 name: aberrant lysosome morphology def: "Deviation from the normal, usual, or expected morphology of the endosome." [DDB:pg] is_a: DDPHENO:0000230 ! aberrant endosome morphology [Term] id: DDPHENO:0001207 name: decreased lysosome size def: "Decrease in relative or proportionate dimensions of the lysosome." [DDB:pg] is_a: DDPHENO:0001205 ! decreased endosome size is_a: DDPHENO:0001206 ! aberrant lysosome morphology [Term] id: DDPHENO:0001208 name: increased lysosome size def: "Increase in relative or proportionate dimensions of the lysosome." [DDB:pg] is_a: DDPHENO:0001204 ! increased endosome size is_a: DDPHENO:0001206 ! aberrant lysosome morphology [Term] id: DDPHENO:0001209 name: aberrant translation def: "Deviation from the normal, usual, or expected events during translation." [DDB:pg] synonym: "aberrant protein biosynthesis" EXACT [] synonym: "aberrant protein synthesis" EXACT [] synonym: "aberrant protein translation" EXACT [] is_a: DDPHENO:0001155 ! aberrant macromolecule biosynthesis [Term] id: DDPHENO:0001210 name: abolished translation def: "Complete inability for translation." [DDB:pg] synonym: "abolished protein biosynthesis" EXACT [] synonym: "abolished protein synthesis" EXACT [] synonym: "abolished protein translation" EXACT [] is_a: DDPHENO:0001209 ! aberrant translation [Term] id: DDPHENO:0001211 name: decreased translation def: "Reduction in extent, amount, or degree of translation." [DDB:pg] synonym: "decreased protein biosynthesis" EXACT [] synonym: "decreased protein synthesis" EXACT [] synonym: "decreased protein translation" EXACT [] is_a: DDPHENO:0001209 ! aberrant translation [Term] id: DDPHENO:0001212 name: increased translation def: "Increase in extent, amount, or degree of translation." [DDB:pg] synonym: "increased protein biosynthesis" EXACT [] synonym: "increased protein synthesis" EXACT [] synonym: "increased protein translation" EXACT [] is_a: DDPHENO:0001209 ! aberrant translation [Term] id: DDPHENO:0001213 name: decreased calcium-dependent cell-cell adhesion def: "Reduction in extent, amount, or degree of calcium-dependentcell-cell adhesion." [DDB:pf] synonym: "decreased EDTA-sensitive cell-cell adhesion" EXACT [] is_a: DDPHENO:0000138 ! decreased cell-cell adhesion [Term] id: DDPHENO:0001214 name: decreased calcium-independent cell-cell adhesion def: "Reduction in extent, amount, or degree of calcium-independentcell-cell adhesion." [DDB:pf] synonym: "decreased EDTA-resistant cell-cell adhesion" EXACT [] is_a: DDPHENO:0000138 ! decreased cell-cell adhesion [Term] id: DDPHENO:0001215 name: increased calcium-dependent cell-cell adhesion def: "Increase in extent, amount, or degree of calcium-dependent cell-cell adhesion." [DDB:pf] synonym: " increased EDTA-sensitive cell-cell adhesion" EXACT [] is_a: DDPHENO:0000109 ! increased cell-cell adhesion [Term] id: DDPHENO:0001216 name: increased calcium-independent cell-cell adhesion def: "Increase in extent, amount, or degree of calcium-independent cell-cell adhesion." [DDB:pf] synonym: "increased EDTA-resistant cell-cell adhesion" EXACT [] is_a: DDPHENO:0000109 ! increased cell-cell adhesion [Term] id: DDPHENO:0001217 name: aberrant cellular localization def: "Deviation from the normal, usual, or expected events during localization." [DDB:pg] is_a: DDPHENO:0001009 ! aberrant localization [Term] id: DDPHENO:0001218 name: aberrant organelle localization def: "Deviation from the normal, usual, or expected localization of an organelle." [DDB:pg] is_a: DDPHENO:0001217 ! aberrant cellular localization [Term] id: DDPHENO:0001219 name: aberrant Golgi localization def: "Deviation from the normal, usual, or expected localization of the Golgi apparatus." [DDB:pg] is_a: DDPHENO:0001218 ! aberrant organelle localization [Term] id: DDPHENO:0001220 name: aberrant nucleus localization def: "Deviation from the normal, usual, or expected localization of the nucleus." [DDB:pg] is_a: DDPHENO:0001218 ! aberrant organelle localization [Term] id: DDPHENO:0001221 name: aberrant centrosome localization def: "Deviation from the normal, usual, or expected localization of the centrosome." [DDB:pg] is_a: DDPHENO:0001218 ! aberrant organelle localization [Term] id: DDPHENO:0001222 name: aberrant phagolysosome formation def: "Deviation from the normal, usual, or expected events during phagolysosome formation." [DDB:pf] synonym: "aberrant late phagosome formation" RELATED [] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0001223 name: decreased phagolysosome formation def: "Reduction in extent, amount, or degree of phagolysosome formation." [DDB:pf] synonym: "decreased late phagosome formation" RELATED [] is_a: DDPHENO:0001222 ! aberrant phagolysosome formation [Term] id: DDPHENO:0001224 name: aberrant positive chemotaxis def: "Deviation from the normal, usual, or expected events during the locomotory response guided by increasing chemical concentration gradient." [DDB:pg] is_a: DDPHENO:0001122 ! aberrant chemotaxis [Term] id: DDPHENO:0001225 name: aberrant negative chemotaxis def: "Deviation from the normal, usual, or expected events during the locomotory response guided by increasing chemical concentration gradient." [DDB:pg] is_a: DDPHENO:0001122 ! aberrant chemotaxis [Term] id: DDPHENO:0001226 name: aberrant cellular response to extracellular stimulus def: "Deviation from the normal, usual, or expected during the cellular response to extracellular stimulus." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001227 name: aberrant response to prestarvation factor def: "Deviation from the normal, usual, or expected events during the response to prestarvation factor (PSF) found in conditioned media (CM)." [DDB:pg] synonym: "aberrant response to PSF" EXACT [] is_a: DDPHENO:0001226 ! aberrant cellular response to extracellular stimulus [Term] id: DDPHENO:0001228 name: aberrant detection of prestarvation factor def: "Deviation from the normal, usual, or expected events during the detection of prestarvation factor (PSF) found in conditioned media (CM)." [DDB:pg] synonym: "aberrant detection of PSF" EXACT [] synonym: "aberrant sensing of prestarvation factor" EXACT [] synonym: "aberrant sensing of PSF" EXACT [] is_a: DDPHENO:0001227 ! aberrant response to prestarvation factor [Term] id: DDPHENO:0001229 name: decreased 3',5'-cyclic-AMP phosphodiesterase activity def: "Reduction in extent, amount, or degree of 3',5'-cyclic-AMP phosphodiesterase activity." [DDB:pf] synonym: "decreased cAMP-specific phosphodiesterase activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001230 name: decreased 3',5'-cyclic-GMP phosphodiesterase activity def: "Reduction in extent, amount, or degree of 3',5'-cyclic-GMP phosphodiesterase activity." [DDB:pf] synonym: "decreased cGMP-specific phosphodiesterase activity" RELATED [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001231 name: abolished protein secretion def: "Complete inability for protein secretion." [DDB:pf] is_a: DDPHENO:0001030 ! aberrant protein secretion [Term] id: DDPHENO:0001232 name: increased protein secretion def: "Increase in extent, amount, or degree of protein secretion." [DDB:pf] is_a: DDPHENO:0001030 ! aberrant protein secretion is_a: DDPHENO:0001337 ! increased protein localization [Term] id: DDPHENO:0001233 name: decreased protein secretion def: "Reduction in extent, amount, or degree of protein secretion." [DDB:pf] is_a: DDPHENO:0001030 ! aberrant protein secretion is_a: DDPHENO:0001338 ! decreased protein localization [Term] id: DDPHENO:0001234 name: aberrant mitochondrion organization and biogenesis def: "Deviation from the normal, usual, or expected events during mitochondrion organization and biogenesis." [DDB:pf] is_a: DDPHENO:0001043 ! aberrant organelle organization and biogenesis [Term] id: DDPHENO:0001235 name: decreased intracellular ATP level def: "Decrease in amount or accumulation of intracellular ATP." [DDB:pf] synonym: " synonym: "decreased cytosolic ATP level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001236 name: increased intracellular ATP level def: "Increase in amount or accumulation of intracellular ATP." [DDB:pf] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001237 name: aberrant lysosome organization and biogenesis def: "Deviation from the normal, usual, or expected events during organelle organization and biogenesis." [DDB:pg] is_a: DDPHENO:0001043 ! aberrant organelle organization and biogenesis [Term] id: DDPHENO:0001238 name: aberrant post-lysosome organization and biogenesis def: "Deviation from the normal, usual, or expected events during post-lysosome organization and biogenesis." [DDB:pg] synonym: "aberrant lysosome maturation" RELATED [] is_a: DDPHENO:0001237 ! aberrant lysosome organization and biogenesis [Term] id: DDPHENO:0001239 name: abolished cell motility def: "Complete inability for cell motility." [DDB:pg] is_a: DDPHENO:0000264 ! aberrant cell motility [Term] id: DDPHENO:0001240 name: decreased CRAC localization to the plasma membrane def: "Reduction in the ability for localization of CRAC (dagA) from the cytoplasm to the plasma membrane in response to a stimulus." [DDB:pf] synonym: "decreased CRAC translocation" RELATED [] is_a: DDPHENO:0001387 ! aberrant CRAC localization to the plasma membrane is_a: DDPHENO:0001395 ! decreased localization of protein to the plasma membrane [Term] id: DDPHENO:0001241 name: aberrant protein level def: "Deviation from the normal, usual, or expected level of proteins." [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001242 name: decreased protein level def: "Reduction in extent, amount, or degree of protein expression." [DDB:pf] is_a: DDPHENO:0001241 ! aberrant protein level [Term] id: DDPHENO:0001243 name: increased protein level def: "Increase in extent, amount, or degree of protein expression." [DDB:pf] is_a: DDPHENO:0001241 ! aberrant protein level [Term] id: DDPHENO:0001244 name: abolished protein level def: "Complete elimination of protein expression." [DDB:pf] is_a: DDPHENO:0001241 ! aberrant protein level [Term] id: DDPHENO:0001245 name: aberrant cAMP wave formation def: "Deviation from the normal, usual, or expected events during cAMP wave formation." [DDB:pf] synonym: "aberrant cAMP wave propagation" RELATED [] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0001246 name: abolished cAMP wave formation def: "Complete inability for cAMP wave formation." [DDB:pf] synonym: "abolished cAMP wave propagation" RELATED [] is_a: DDPHENO:0001245 ! aberrant cAMP wave formation [Term] id: DDPHENO:0001247 name: aberrant protein amino acid methylation def: "Deviation from the normal, usual, or expected events during protein amino acid methylation." [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001248 name: abolished protein amino acid methylation def: "Complete inability for protein amino acid methylation." [DDB:pf] is_a: DDPHENO:0001247 ! aberrant protein amino acid methylation [Term] id: DDPHENO:0001249 name: abolished C-terminal protein amino acid methylation def: "Complete inability for C-terminal protein amino acid methylation." [DDB:pf] is_a: DDPHENO:0001248 ! abolished protein amino acid methylation [Term] id: DDPHENO:0001250 name: abolished cell polarity def: "Complete inability to establish cell polarity." [DDB:pf] is_a: DDPHENO:0001029 ! aberrant establishment and/or maintenance of cell polarity [Term] id: DDPHENO:0001251 name: increased protein kinase B activation def: "Increase in extent, amount, or degree of activation of protein kinase B." [DDB:pg] is_a: DDPHENO:0001061 ! increased protein kinase activation [Term] id: DDPHENO:0001252 name: abolished MAP kinase activation def: "Complete inability for activation of MAP kinase upon stimulus." [DDB:pg] synonym: "abolished erk2 activation" NARROW [] synonym: "abolished erkB activation" NARROW [] is_a: DDPHENO:0001062 ! abolished protein kinase activation [Term] id: DDPHENO:0001253 name: decreased MAP kinase activation def: "Reduction in extent, amount, or degree of activation of a MAP kinase." [DDB:pg] synonym: "decreased erk2 activation" RELATED [] synonym: "decreased erkB activation" NARROW [] is_a: DDPHENO:0001058 ! decreased protein kinase activation [Term] id: DDPHENO:0001254 name: increased MAP kinase activation def: "Increase in extent, amount, or degree of activation of a MAP kinase." [DDB:pg] synonym: "increased erk2 activation" NARROW [] synonym: "increased erkB activation" NARROW [] is_a: DDPHENO:0001061 ! increased protein kinase activation [Term] id: DDPHENO:0001255 name: aberrant binding def: "Deviation from the normal, usual, or expected binding." [DDB:pg] is_a: DDPHENO:0001171 ! aberrant molecular function [Term] id: DDPHENO:0001256 name: increased catalytic activity def: "Increase in extent, amount, or degree of catalysis by an enzyme." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001257 name: decreased catalytic activity def: "A reduction in extent, amount, or degree of catalysis by an enzyme." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001258 name: increased binding def: "Increase in extent, amount, or degree of binding." [DDB:pg] is_a: DDPHENO:0001255 ! aberrant binding [Term] id: DDPHENO:0001259 name: decreased binding def: "A reduction in extent, amount, or degree of binding." [DDB:pg] is_a: DDPHENO:0001255 ! aberrant binding [Term] id: DDPHENO:0001260 name: increased cAMP binding def: "Increased in extent, amount, or degree of binding to cAMP." [DDB:pg] synonym: "increased 3',5'-cyclic-AMP binding" EXACT [] is_a: DDPHENO:0001258 ! increased binding [Term] id: DDPHENO:0001261 name: decreased cAMP binding def: "A reduction in extent, amount, or degree of binding to cAMP." [DDB:pg] synonym: "decreased 3',5'-cyclic-AMP binding" EXACT [] is_a: DDPHENO:0001259 ! decreased binding [Term] id: DDPHENO:0001262 name: aberrant adaptation of signaling pathway def: "Deviation from the normal, usual, or expected events during the adaptation of a signaling pathway." [DDB:pg] is_a: DDPHENO:0001118 ! aberrant signal transduction [Term] id: DDPHENO:0001263 name: aberrant autophagic cell death def: "Deviation from the normal, usual, or expected events during autophagic cell death." [DDB:pf] is_a: DDPHENO:0001267 ! aberrant cell death [Term] id: DDPHENO:0001264 name: abolished autophagic cell death def: "Complete inability for autophagic cell death." [DDB:pf] is_a: DDPHENO:0001263 ! aberrant autophagic cell death [Term] id: DDPHENO:0001265 name: increased autophagic cell death def: "Increase in extent, amount, or degree of autophagic cell death." [DDB:pf] is_a: DDPHENO:0001263 ! aberrant autophagic cell death [Term] id: DDPHENO:0001266 name: decreased autophagic cell death def: "Reduction in extent, amount, or degree of autophagic cell death." [DDB:pf] is_a: DDPHENO:0001263 ! aberrant autophagic cell death [Term] id: DDPHENO:0001267 name: aberrant cell death def: "Deviation from the normal, usual, or expected events during cell death." [DDB:pf] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001268 name: aberrant non-apoptotic programmed cell death def: "Deviation from the normal, usual, or expected events during non-apoptotic programmed cell death." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001269 name: abolished non-apoptotic programmed cell death def: "Complete inability non-apoptotic programmed cell death." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001270 name: increased non-apoptotic programmed cell death def: "Increase in extent, amount, or degree of non-apoptotic programmed cell death." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001271 name: decreased non-apoptotic programmed cell death def: "Reduction in extent, amount, or degree of non-apoptotic programmed cell death." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001272 name: decreased pseudopod retraction def: "Reduction in extent, amount, or degree of pseudopod retraction." [DDB:pf] is_a: DDPHENO:0001027 ! aberrant pseudopod formation [Term] id: DDPHENO:0001273 name: decreased uropod retraction def: "Reduction in extent, amount, or degree of uropod retraction." [DDB:pf] is_a: DDPHENO:0001048 ! aberrant cell projection biogenesis [Term] id: DDPHENO:0001274 name: abolished phagocytosis def: "Complete inability for phagocytosis." [DDB:pf] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0001275 name: aberrant engulfment during phagocytosis def: "Deviation from the normal, usual, or expected events during engulfment of attached, recognized, external material." [DDB:pf] synonym: "aberrant phagosome formation" RELATED [] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0001276 name: abolished engulfment during phagocytosis def: "Complete inability of engulfment of attached, recognized, external material." [DDB:pf] synonym: "abolished phagosome formation" RELATED [] is_a: DDPHENO:0001275 ! aberrant engulfment during phagocytosis [Term] id: DDPHENO:0001277 name: decreased engulfment during phagocytosis def: "Reduction in extent, amount, or degree of engulfment of attached, recognized, external material." [DDB:pf] synonym: "decreased phagosome formation" RELATED [] is_a: DDPHENO:0001275 ! aberrant engulfment during phagocytosis [Term] id: DDPHENO:0001278 name: aberrant vacuolation def: "Deviation from the normal, usual, or expected events during vacuolation." [DDB:pf] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0001279 name: decreased autophagic vacuole formation def: "Reduction in extent, amount, or degree of autophagic vacuole formation." [DDB:pf] is_a: DDPHENO:0001278 ! aberrant vacuolation [Term] id: DDPHENO:0001280 name: increased 3',5'-cyclic-AMP phosphodiesterase activity def: "Increase in extent, amount, or degree of 3',5'-cyclic-AMP phosphodiesterase activity." [DDB:pg] synonym: "increased cAMP-specific phosphodiesterase activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001281 name: increased 3',5'-cyclic-GMP phosphodiesterase activity def: "Increase in extent, amount, or degree of 3',5'-cyclic-GMP phosphodiesterase activity." [DDB:pg] synonym: "increased cGMP-specific phosphodiesterase activity>" RELATED [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001282 name: increased adenylate cyclase activity def: "Increase in extent, amount, or degree of adenylate cyclase activity." [DDB:pg] synonym: "increased ACA activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001283 name: decreased protein kinase A activity def: "Reduction in extent, amount, or degree of protein kinase A activity." [DDB:pg] synonym: "decreased PKA activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001284 name: decreased Ras guanyl-nucleotide exchange factor activity def: "Redution in extent, amount, or degree of Ras guanyl-nucleotide exchange factor activity." [DDb:pg] synonym: "decreased Ras GEF activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001285 name: decreased adenylate cyclase activity def: "Reduction in extent, amount, or degree of adenylate cyclase activity." [DDB:pg] synonym: "decreased ACA activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001286 name: increased glycogen synthase kinase 3 activity def: "Increase in extent, amount, or degree of glycogen synthase kinase 3 activity." [DDB:pg] synonym: "decreased GSK3 activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001287 name: increased guanylyl cyclase activity def: "Increase in extent, amount, or degree of guanylyl cyclase activity." [DDB:pg] synonym: "increased GC activity" EXACT [] synonym: "increased guanylate cyclase activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001288 name: decreased guanylyl cyclase activity def: "Reduction in extent, amount, or degree of guanylyl cyclase activity." [DDB:pg] synonym: "decreased GC activity" EXACT [] synonym: "decreased guanylate cyclase activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001289 name: abolished catalytic activity def: "Complete absence of catalytic activity." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001290 name: abolished 3',5'-cyclic-AMP phosphodiesterase activity def: "Complete absence of 3',5'-cyclic-AMP phosphodiesterase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001291 name: abolished 3',5'-cyclic-GMP phosphodiesterase activity def: "Complete absence of 3',5'-cyclic-GMP phosphodiesterase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001292 name: abolished actin-dependent ATPase activity def: "Complete absence of actin-dependent ATPase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001293 name: abolished adenylate cyclase activity def: "Complete absence of adenylate cyclase activity." [DDB:pg] synonym: "abolished ACA activity" EXACT [] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001294 name: abolished glycogen synthase kinase 3 activity def: "Complete absence of glycogen synthase kinase 3 activity." [DDB:pg] synonym: "abolished GSK3 activity" EXACT [] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001295 name: abolished guanylyl cyclase activity def: "Complete absence of guanylyl cyclase activity." [DDB:pg] synonym: "abolished GC activity" EXACT [] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001296 name: abolished GTP-gamma-S-stimulated guanylyl cyclase activity def: "Complete absence of GTP-gamma-S-stimulated guanylyl cyclase activity." [DDB:pg] synonym: "abolished GTP-gamma-S-stimulated GSactivity" EXACT [] is_a: DDPHENO:0001295 ! abolished guanylyl cyclase activity [Term] id: DDPHENO:0001297 name: abolished lysosomal enzyme activity def: "Complete absence of lysosomal enzyme activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001298 name: abolished protein kinase A activity def: "Complete absence of protein kinase A activity." [DDB:pg] synonym: "abolished PKA activity" EXACT [] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001299 name: abolished Ras guanyl-nucleotide exchange factor activity def: "Complete absence of Ras guanyl-nucleotide exchange factor activity." [DDB:pg] synonym: "abolished Ras GEF activity" EXACT [] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001300 name: abolished protein kinase B activity def: "Complete absence of protein kinase B activity." [DDB:pg] synonym: "abolished PKB activity" EXACT [] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001301 name: decreased protein kinase B activity def: "Reduction in extent, amount, or degree of protein kinase B activity." [DDB:pg] synonym: "decreased PKB activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001302 name: increased protein kinase B activity def: "Increase in extent, amount, or degree of protein kinase B activity." [DDB:pg] synonym: "increased PKB activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001303 name: aberrant regulation of catalytic activity def: "Deviation from the normal, usual, or expected events during the regulation of a catalytic activity." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity is_a: DDPHENO:0001118 ! aberrant signal transduction [Term] id: DDPHENO:0001304 name: aberrant regulation of adenylate cyclase activity def: "Deviation from the normal, usual, or expected events during the regulation of the activity of adenylate cyclase." [DDB:pg] is_a: DDPHENO:0001303 ! aberrant regulation of catalytic activity [Term] id: DDPHENO:0001305 name: abolished cAMP-induced cGMP pulse def: "Complete inability to produce a cGMP pulse upron cAMP stimulation." [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0001306 name: abolished cAMP-induced cAMP pulse def: "Complete inability to produce a cAMP pulse upron cAMP stimulation." [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0001307 name: abolished activation of Rab GTPase activity def: "Complete inability to activate Rab GTPase activity." [DDB:pg] is_a: DDPHENO:0001142 ! aberrant regulation of Rab GTPase activity is_a: DDPHENO:0001311 ! aberrant activation of GTPase activity [Term] id: DDPHENO:0001308 name: abolished activation of Rac GTPase activity def: "Complete inability to activate Rac GTPase activity." [DDB:pg] synonym: "abolished activation of Rho GTPase activity" RELATED [] is_a: DDPHENO:0001141 ! aberrant regulation of Rac GTPase activity is_a: DDPHENO:0001311 ! aberrant activation of GTPase activity [Term] id: DDPHENO:0001309 name: abolished activation of Ran GTPase activity def: "Complete inability to activate Ran GTPase activity." [DDB:pg] is_a: DDPHENO:0001143 ! aberrant regulation of Ran GTPase activity is_a: DDPHENO:0001311 ! aberrant activation of GTPase activity [Term] id: DDPHENO:0001310 name: abolished activation of Rap GTPase activity def: "Complete inability to activate Rap GTPase activity." [DDB:pg] is_a: DDPHENO:0001144 ! aberrant regulation of Rap GTPase activity is_a: DDPHENO:0001311 ! aberrant activation of GTPase activity [Term] id: DDPHENO:0001311 name: aberrant activation of GTPase activity def: "Deviation from the normal, usual, or expected events during the activation of the activity of a GTPase." [DDB:pg] is_a: DDPHENO:0001137 ! aberrant regulation of GTPase activity [Term] id: DDPHENO:0001312 name: abolished activation of Ras GTPase activity def: "Complete inability to activate Ras GTPase activity." [DDB:pg] is_a: DDPHENO:0001140 ! aberrant regulation of Ras GTPase activity is_a: DDPHENO:0001311 ! aberrant activation of GTPase activity [Term] id: DDPHENO:0001313 name: aberrant peptidyl-proline 4-dioxygenase activity def: "Deviation from the normal, usual, or expected activity of peptidyl-proline 4-dioxygenase." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001314 name: decreased peptidyl-proline 4-dioxygenase activity def: "Reduction in extent, amount, or degree of peptidyl-proline 4-dioxygenase activity." [DDB:pg] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001315 name: increased peptidyl-proline 4-dioxygenase activity def: "Increase in extent, amount, or degree of peptidyl-proline 4-dioxygenase activity." [DDB:pg] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001316 name: abolished peptidyl-proline 4-dioxygenase activity def: "Complete absence of peptidyl-proline 4-dioxygenase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001317 name: aberrant protein modification def: "Deviation from the normal, usual, or expected during protein modification." [DDB:pg] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001318 name: aberrant peptidyl-proline modification def: "Deviation from the normal, usual, or expected during peptidyl-proline modification." [DDB:pg] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0001319 name: increased peptidyl-proline modification def: "Increase in level of modification of proline residues on a peptide." [DDB:pg] is_a: DDPHENO:0001318 ! aberrant peptidyl-proline modification is_a: DDPHENO:0001326 ! increased protein modification [Term] id: DDPHENO:0001320 name: decreased peptidyl-proline modification def: "Reduction in level of modification of proline residues on a peptide." [DDB:pg] is_a: DDPHENO:0001318 ! aberrant peptidyl-proline modification is_a: DDPHENO:0001327 ! decreased protein modification [Term] id: DDPHENO:0001321 name: aberrant peptidyl-proline hydroxylation def: "Deviation from the normal, usual, or expected during peptidyl-proline hydroxylation." [DDB:pg] is_a: DDPHENO:0001318 ! aberrant peptidyl-proline modification [Term] id: DDPHENO:0001322 name: abolished peptidyl-proline modification def: "Complete inability for peptidyl-proline modification." [DDB:pg] is_a: DDPHENO:0001318 ! aberrant peptidyl-proline modification is_a: DDPHENO:0001328 ! abolished protein modification [Term] id: DDPHENO:0001323 name: increased peptidyl-proline hydroxylation def: "Increase in level of hydroxylation of proline residues on a peptide." [DDB:pg] is_a: DDPHENO:0001321 ! aberrant peptidyl-proline hydroxylation is_a: DDPHENO:0001326 ! increased protein modification [Term] id: DDPHENO:0001324 name: decreased peptidyl-proline hydroxylation def: "Reduction in level of hydroxylation of proline residues on a peptide." [DDB:pg] is_a: DDPHENO:0001321 ! aberrant peptidyl-proline hydroxylation is_a: DDPHENO:0001327 ! decreased protein modification [Term] id: DDPHENO:0001325 name: abolished peptidyl-proline hydroxylation def: "Complete inability for peptidyl-proline hydroxylation." [DDB:pg] is_a: DDPHENO:0001321 ! aberrant peptidyl-proline hydroxylation is_a: DDPHENO:0001328 ! abolished protein modification [Term] id: DDPHENO:0001326 name: increased protein modification def: "Increase in level of modification of a protein." [DDB:pg] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0001327 name: decreased protein modification def: "Reduction in level of modification of a protein." [DDB:pg] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0001328 name: abolished protein modification def: "Complete inability for protein modification." [DDB:pg] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0001329 name: decreased extracellular cAMP level def: "Reduction in amount or accumulation of intracellular cAMP." [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0001330 name: increased extracellular cAMP level def: "Increase in amount or accumulation of extracellular cAMP." [DDB:pg] is_a: DDPHENO:0001038 ! aberrant cAMP signaling during aggregation [Term] id: DDPHENO:0001331 name: aberrant catalase activity def: "Deviation from the normal, usual, or expected activity catalase." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001332 name: abolished catalase activity def: "Complete absence of catalase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001333 name: decreased catalase activity def: "Reduction in extent, amount, or degree of catalase activity." [DDB:pg] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001334 name: increased catalase activity def: "Increase in extent, amount, or degree of catalase activity." [DDB:pg] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001335 name: aberrant localization of protein to the plasma membrane def: "Deviation from the normal, usual, or expected events during protein localization from the cytoplasm to the plasma membrane in responsee to a stimulus." [DDB:pg] is_a: DDPHENO:0000471 ! aberrant protein localization is_a: DDPHENO:0001217 ! aberrant cellular localization [Term] id: DDPHENO:0001336 name: aberrant localization of protein to the nucleus def: "Deviation from the normal, usual, or expected events during protein localization to the nucleus." [DDB:pg] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001337 name: increased protein localization def: "Increase in amount or accumulation of a protein at a certain location." [DDB:pg] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001338 name: decreased protein localization def: "Reduction in amount or accumulation of a protein at a certain location." [DDB:pg] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001339 name: abolished secretion of lysosomal enzyme def: "Complete inability for secretion of lysosomal enzyme." [DDB:pg] is_a: DDPHENO:0001231 ! abolished protein secretion [Term] id: DDPHENO:0001340 name: decreased localization of protein to the nucleus def: "Reduction in amount or accumulation of a protein in the nucleus." [DDB:pg] is_a: DDPHENO:0001336 ! aberrant localization of protein to the nucleus is_a: DDPHENO:0001338 ! decreased protein localization [Term] id: DDPHENO:0001341 name: increased localization of protein to the nucleus def: "Increase in amount or accumulation of a protein in the nucleus." [DDB:pg] is_a: DDPHENO:0001336 ! aberrant localization of protein to the nucleus is_a: DDPHENO:0001337 ! increased protein localization [Term] id: DDPHENO:0001342 name: aberrant protein phosphorylation def: "Deviation from the normal, usual, or expected events during phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0001343 name: increased protein phosphorylation def: "Increase in amount or accumulation of phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001342 ! aberrant protein phosphorylation [Term] id: DDPHENO:0001344 name: decreased protein phosphorylation def: "Reduction in amount or accumulation of phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001342 ! aberrant protein phosphorylation [Term] id: DDPHENO:0001345 name: aberrant protein tyrosine phosphorylation def: "Deviation from the normal, usual, or expected events during tyrosine phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001342 ! aberrant protein phosphorylation [Term] id: DDPHENO:0001346 name: increased protein tyrosine phosphorylation def: "Increase in amount or accumulation of tyrosine phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001343 ! increased protein phosphorylation is_a: DDPHENO:0001345 ! aberrant protein tyrosine phosphorylation [Term] id: DDPHENO:0001347 name: decreased protein theronine phosphorylation def: "Reduction in amount or accumulation of threonine phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001344 ! decreased protein phosphorylation is_a: DDPHENO:0001345 ! aberrant protein tyrosine phosphorylation is_a: DDPHENO:0001349 ! aberrant protein threonine phosphorylation [Term] id: DDPHENO:0001348 name: aberrant protein serine phosphorylation def: "Deviation from the normal, usual, or expected events during serine phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001342 ! aberrant protein phosphorylation [Term] id: DDPHENO:0001349 name: aberrant protein threonine phosphorylation def: "Deviation from the normal, usual, or expected events during threonine phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001342 ! aberrant protein phosphorylation [Term] id: DDPHENO:0001350 name: decreased protein serine phosphorylation def: "Reduction in amount or accumulation of serine phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001344 ! decreased protein phosphorylation is_a: DDPHENO:0001348 ! aberrant protein serine phosphorylation [Term] id: DDPHENO:0001351 name: increased protein serine phosphorylation def: "Increase in amount or accumulation of serine phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001343 ! increased protein phosphorylation is_a: DDPHENO:0001348 ! aberrant protein serine phosphorylation [Term] id: DDPHENO:0001352 name: decreased protein tyrosine phosphorylation is_a: DDPHENO:0001344 ! decreased protein phosphorylation [Term] id: DDPHENO:0001353 name: increased protein theronine phosphorylation def: "Increase in amount or accumulation of threonine phosphorylation of a protein." [DDB:pg] is_a: DDPHENO:0001343 ! increased protein phosphorylation is_a: DDPHENO:0001349 ! aberrant protein threonine phosphorylation [Term] id: DDPHENO:0001354 name: aberrant basal disc formation def: "Deviation from the normal, usual, or expected during the formation of the basal disc." [DDB:pg] is_a: DDPHENO:0000009 ! aberrant fruiting body morphology [Term] id: DDPHENO:0001355 name: decreased basal disc size def: "Reduction in relative or proportionate dimensions of the basal disc." [DDB:pg] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0001356 name: abolished basal disc formation def: "Complete absence of the basal disc." [DDB:pg] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0001357 name: aberrant outer basal disc formation def: "Deviation from the normal, usual, or expected during the formation of the outer basal disc." [DDB:pg] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0001358 name: aberrant inner basal disc formation def: "Deviation from the normal, usual, or expected during the formation of the inner basal disc." [DDB:pg] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0001359 name: abolished outer basal disc formation def: "Complete absence of the outer basal disc." [DDB:pg] is_a: DDPHENO:0001356 ! abolished basal disc formation is_a: DDPHENO:0001357 ! aberrant outer basal disc formation [Term] id: DDPHENO:0001360 name: abolished inner basal disc formation def: "Complete absence of the inner basal disc." [DDB:pg] is_a: DDPHENO:0001356 ! abolished basal disc formation is_a: DDPHENO:0001358 ! aberrant inner basal disc formation [Term] id: DDPHENO:0001361 name: decreased inner basal disc size def: "Reduction in relative or proportionate dimensions of the inner basal disc." [DDB:pg] is_a: DDPHENO:0001355 ! decreased basal disc size [Term] id: DDPHENO:0001362 name: decreased outer basal disc size def: "Reduction in relative or proportionate dimensions of the outer basal disc." [DDB:pg] is_a: DDPHENO:0001355 ! decreased basal disc size [Term] id: DDPHENO:0001363 name: increased inner basal disc size def: "Increase in relative or proportionate dimensions of the inner basal disc." [DDB:pg] is_a: DDPHENO:0000269 ! increased basal disc size [Term] id: DDPHENO:0001364 name: increased outer basal disc size def: "Increase in relative or proportionate dimensions of the outer basal disc." [DDB:pg] is_a: DDPHENO:0000269 ! increased basal disc size [Term] id: DDPHENO:0001365 name: aberrant lower cup formation def: "Deviation from the normal, usual, or expected morphology of the lower cup." [DDB:pg] is_a: DDPHENO:0000384 ! aberrant sorus morphology [Term] id: DDPHENO:0001366 name: aberrant upper cup formation def: "Deviation from the normal, usual, or expected morphology of the upper cup." [DDB:pg] is_a: DDPHENO:0000384 ! aberrant sorus morphology [Term] id: DDPHENO:0001367 name: abolished lower cup formation def: "Complete inability to form a lower cup." [DDB:pg] is_a: DDPHENO:0001365 ! aberrant lower cup formation [Term] id: DDPHENO:0001368 name: abolished upper cup formation def: "Complete inability to form an upper cup." [DDB:pg] is_a: DDPHENO:0001366 ! aberrant upper cup formation [Term] id: DDPHENO:0001369 name: increased lower cup size def: "Increase in relative or proportionate dimensions of the lower cup." [DDB:pg] is_a: DDPHENO:0001365 ! aberrant lower cup formation [Term] id: DDPHENO:0001370 name: decreased lower cup size def: "Reduction in relative or proportionate dimensions of the lower cup." [DDB:pg] is_a: DDPHENO:0001365 ! aberrant lower cup formation [Term] id: DDPHENO:0001371 name: increased upper cup size def: "Increase in relative or proportionate dimensions of the upper cup." [DDB:pg] is_a: DDPHENO:0001366 ! aberrant upper cup formation [Term] id: DDPHENO:0001372 name: decreased upper cup size def: "Reduction in relative or proportionate dimensions of the upper cup." [DDB:pg] is_a: DDPHENO:0001366 ! aberrant upper cup formation [Term] id: DDPHENO:0001373 name: decreased chemotaxis to arachidonic acid def: "Reduction in extent, amount, or degree of chemotaxis in response to arachidonic acid." [DDB:pf] is_a: DDPHENO:0000099 ! decreased chemotaxis rate [Term] id: DDPHENO:0001374 name: increased chemotaxis to arachidonic acid def: "Increase in extent, amount, or degree of chemotaxis in response to arachidonic acid." [DDB:pf] is_a: DDPHENO:0000400 ! increased chemotaxis rate [Term] id: DDPHENO:0001375 name: aberrant cellular homeostasis def: "Deviation from the normal, usual, or expected events during cellular homeostasis." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001376 name: increased intracellular glycogen level def: "Increase in amount or accumulation of intracellular glycogen." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001377 name: increased intracellular pH level def: "Increase in amount or accumulation of hydrogen ions in the cell." [DDB:pg] is_a: DDPHENO:0001455 ! aberrant intracellular pH level [Term] id: DDPHENO:0001378 name: decreased extracellular ammonia level def: "Reduction in amount or accumulation of extracellular ammonia." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001379 name: decreased intracellular ammonia level def: "Reduction in amount or accumulation of intracellular ammonia." [DDB:pg] synonym: " synonym: "decreased cytosolic ammonia level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001380 name: increased intracellular ammonia level def: "Increase in amount or accumulation of intracellular ammonia." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001381 name: decreased extracellular glucose level def: "Reduction in extent, amount or accumulation of extracellular glucose." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001382 name: increased extracellular glucose level def: "Increase in amount or accumulation of extracellular glucose." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001383 name: decreased extracellular pteridine level is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001384 name: decreased cytochrome C oxidase activity def: "Reduction in extent, amount, or degree of cytochrome C oxidase activity." [DDB:pg] synonym: "decreased COX activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001385 name: increased cytochrome C oxidase activity def: "Increase in extent, amount, or degree of cytochrome C oxidase activity." [DDB:pg] synonym: "increased COX activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001386 name: abolished cytochrome C oxidase activity def: "Complete absence of cytochrome C oxidase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001387 name: aberrant CRAC localization to the plasma membrane def: "Deviation from the normal, usual, or expected events during CRAC (dagA) protein localization from the cytoplasm to the plasma membrane in responsee to a stimulus." [DDB:pg] is_a: DDPHENO:0001335 ! aberrant localization of protein to the plasma membrane [Term] id: DDPHENO:0001388 name: increased CRAC localization to the plasma membrane def: "Increase in the ability for localization of CRAC (dagA) from the cytoplasm to the plasma membrane in response to a stimulus." [DDB:pg] is_a: DDPHENO:0001387 ! aberrant CRAC localization to the plasma membrane is_a: DDPHENO:0001396 ! increased localization of protein to the plasma membrane [Term] id: DDPHENO:0001389 name: aberrant localization of protein to the cytoplasm def: "Deviation from the normal, usual, or expected events during protein localization of a protein to the cytoplasm." [DDB:pg] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001390 name: increased localization of protein to the cytoplasm def: "Increase in amount or accumulation of a protein in the cytoplasm." [DDB:pg] is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001389 ! aberrant localization of protein to the cytoplasm [Term] id: DDPHENO:0001391 name: decreased localization of protein to the cytoplasm def: "Reduction in amount or accumulation of a protein in the cytoplasm." [DDB:pg] is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001389 ! aberrant localization of protein to the cytoplasm [Term] id: DDPHENO:0001392 name: abolished localization of protein to the cytoplasm def: "Complete inability for a protein to localize to the cytoplasm." [DDB:pf, DDB:pg] is_a: DDPHENO:0001389 ! aberrant localization of protein to the cytoplasm is_a: DDPHENO:0001393 ! abolished protein localization [Term] id: DDPHENO:0001393 name: abolished protein localization def: "Complete inability for a protein to localize to a cellular compartment or structure." [DDB:pf, DDB:pg] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001394 name: abolished localization of protein to the plasma membrane def: "Complete inability for a protein to localize to the plasma membrane." [DDB:pf, DDB:pg] is_a: DDPHENO:0001335 ! aberrant localization of protein to the plasma membrane is_a: DDPHENO:0001393 ! abolished protein localization [Term] id: DDPHENO:0001395 name: decreased localization of protein to the plasma membrane def: "Reduction in the ability for localization of a protein from the cytoplasm to the plasma membrane in response to a stimulus." [DDB:pg] is_a: DDPHENO:0001335 ! aberrant localization of protein to the plasma membrane is_a: DDPHENO:0001338 ! decreased protein localization [Term] id: DDPHENO:0001396 name: increased localization of protein to the plasma membrane def: "Increase in the ability for localization of a protein from the cytoplasm to the plasma membrane in response to a stimulus." [DDB:pg] is_a: DDPHENO:0001335 ! aberrant localization of protein to the plasma membrane is_a: DDPHENO:0001337 ! increased protein localization [Term] id: DDPHENO:0001397 name: increased period of cAMP wave formation def: "Extended duration for cAMP wave formation." [DDB:pf] synonym: "prolonged cAMP wave formation" RELATED [] is_a: DDPHENO:0001245 ! aberrant cAMP wave formation [Term] id: DDPHENO:0001398 name: decreased period cAMP wave formation def: "Shortened duration for cAMP wave formation." [DDB:pf] synonym: "shortened cAMP wave formation" RELATED [] is_a: DDPHENO:0001245 ! aberrant cAMP wave formation [Term] id: DDPHENO:0001399 name: abolished localization of protein to microtubules def: "Complete inability for a protein to localize to microltubules." [DDB:pf] is_a: DDPHENO:0001393 ! abolished protein localization [Term] id: DDPHENO:0001400 name: abolished localization of protein to the microtubule organizing center def: "Complete inability for a protein to localize to microtubule organizing center." [DDB:pf] synonym: "abolished localization of protein to MTOC" EXACT [] is_a: DDPHENO:0001393 ! abolished protein localization [Term] id: DDPHENO:0001401 name: decreased localization of protein to the microtubule organizing center def: "Reduction in amount or accumulation of a protein in the microtubule organizing center." [DDB:pf] synonym: "decreased localization of protein to the MTOC" EXACT [] is_a: DDPHENO:0001338 ! decreased protein localization [Term] id: DDPHENO:0001402 name: decreased localization of protein to microtubules def: "Reduction in amount or accumulation of a protein at the microtubules." [DDB:pf] is_a: DDPHENO:0001338 ! decreased protein localization [Term] id: DDPHENO:0001403 name: increased localization of protein to microtubules def: "Increase in amount or accumulation of a protein at the microtubules." [DDB:pf] is_a: DDPHENO:0001337 ! increased protein localization [Term] id: DDPHENO:0001404 name: increased localization of protein to the microtubule organizing center def: "Increase in amount or accumulation of a protein in the microtubule organizing center." [DDB:pf] synonym: "increased localization of protein to the MTOC" EXACT [] is_a: DDPHENO:0001337 ! increased protein localization [Term] id: DDPHENO:0001405 name: abolished localization of protein to coated pits def: "Complete inability for a protein to localize to coated pits." [DDB:pf] synonym: "abolished localization of protein to clathrin-coated pits" EXACT [] is_a: DDPHENO:0001393 ! abolished protein localization is_a: DDPHENO:0001408 ! aberrant localization of a protein to coated pits [Term] id: DDPHENO:0001406 name: decreased localization of protein to coated pits def: "Reduction in amount or accumulation of a protein to coated pits." [DDB:pf] synonym: "decreased localization of protein to clathrin-coated pits " EXACT [] is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001408 ! aberrant localization of a protein to coated pits [Term] id: DDPHENO:0001407 name: increased localization of protein to coated pits def: "Increase in amount or accumulation of a protein to coated pits." [DDB:pf] synonym: "increased localization of protein to clathrin-coated pits " RELATED [] is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001408 ! aberrant localization of a protein to coated pits [Term] id: DDPHENO:0001408 name: aberrant localization of a protein to coated pits def: "Deviation from the normal, usual, or expected events during protein localization of a protein to coated pits." [DDB:pf] synonym: "aberrant localization of a protein to clathrin-coated pits" RELATED [] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001409 name: abolished phosphoinositide binding def: "Complete absence of phosphoinositide binding." [DDB:pf] is_a: DDPHENO:0001255 ! aberrant binding [Term] id: DDPHENO:0001410 name: abolished phosphatidylinositol-4,5-bisphosphate binding def: "Complete absence of phosphatidylinositol-4,5-bisphosphate binding." [DDB:pf] is_a: DDPHENO:0001409 ! abolished phosphoinositide binding [Term] id: DDPHENO:0001411 name: aberrant response to conditioned medium factor def: "Deviation from the normal, usual, or expected events during the response to conditioned medium factor (CMF) found in conditioned media (CM)." [DDB:pf] synonym: "aberrant response to CMF" RELATED [] is_a: DDPHENO:0001226 ! aberrant cellular response to extracellular stimulus [Term] id: DDPHENO:0001412 name: aberrant localization of a protein to the pseudopodium def: "Deviation from the normal, usual, or expected events during protein localization to pseudopodia." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001413 name: decreased localization of protein to the pseudopodium def: "Reduction in amount or accumulation of a protein in pseudopodia." [DDB:pf] is_a: DDPHENO:0001338 ! decreased protein localization [Term] id: DDPHENO:0001414 name: increased localization of protein to the pseudopodium def: "Increase in amount or accumulation of a protein in the pseudopodium." [DDB:pf] is_a: DDPHENO:0001337 ! increased protein localization [Term] id: DDPHENO:0001415 name: increased fruiting body size def: "Increase in relative or proportionate dimensions of the fruiting body." [DDB:pf] synonym: "large fruiting body" RELATED [] is_a: DDPHENO:0000009 ! aberrant fruiting body morphology [Term] id: DDPHENO:0001416 name: aberrant cell separation during cytokinesis def: "Deviation from the normal, usual, or expected events during cell separation during cytokinesis." [DDB:pf] is_a: DDPHENO:0000149 ! aberrant cytokinesis [Term] id: DDPHENO:0001417 name: delayed cell separation during cytokinesis is_a: DDPHENO:0001169 ! delayed cytokinesis is_a: DDPHENO:0001416 ! aberrant cell separation during cytokinesis [Term] id: DDPHENO:0001418 name: aberrant cell cycle def: "Deviation from the normal, usual, or expected cell cycle event." [DDB:pf] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001419 name: aberrant spindle organization def: "Deviation from the normal, usual, or expected during spindle organization." [DDB:pf] is_a: DDPHENO:0001418 ! aberrant cell cycle [Term] id: DDPHENO:0001420 name: precocious spindle elongation def: "Early onset or faster progression through spindle elongation." [DDB:pf] is_a: ID:0000003 ! aberrant spindle elongation [Term] id: DDPHENO:0001421 name: decreased spindle stabilization def: "Reduction in spindle stabilization." [DDB:pf] is_a: ID:0000001 ! aberrant spindle stabilization [Term] id: DDPHENO:0001422 name: aberrant sister chromosome segregation def: "Deviation from the normal, usual, or expected events during sister chromosome segragation, resulting in an abnormal number of chromosomes." [DDB:pf] synonym: "aneuploidy" RELATED [] is_a: DDPHENO:0001418 ! aberrant cell cycle [Term] id: DDPHENO:0001423 name: aberrant nuclear envelope morphology def: "Deviation from the normal, usual, or expected morphology of the nuclear envelope." [DDB:pf] is_a: DDPHENO:0000263 ! aberrant nucleus morphology [Term] id: DDPHENO:0001424 name: aberrant perinuclear space def: "Deviation from the normal, usual, or expected morphology of the perinuclear space." [DDB:pf] synonym: "aberrant nuclear membrane lumen" EXACT [] is_a: DDPHENO:0001423 ! aberrant nuclear envelope morphology [Term] id: DDPHENO:0001425 name: aberrant centrosome organization def: "Deviation from the normal, usual, or expected events during centrosome organization." [DDB:pf] is_a: DDPHENO:0001043 ! aberrant organelle organization and biogenesis [Term] id: DDPHENO:0001426 name: increased number of centrosomes def: "Quantitative increase in centrosomes." [DDB:pf] is_a: DDPHENO:0001425 ! aberrant centrosome organization [Term] id: DDPHENO:0001427 name: aberrant localization of a protein to the nuclear envelope def: "Deviation from the normal, usual, or expected events during protein localization to the nuclear envelope." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001428 name: abolished localization of a protein to the nuclear envelope def: "Complete inability for a protein to localize to the nuclear envelope." [DDB:pf] is_a: DDPHENO:0001427 ! aberrant localization of a protein to the nuclear envelope [Term] id: DDPHENO:0001429 name: decreased localization of a protein to the nuclear envelope is_a: DDPHENO:0001427 ! aberrant localization of a protein to the nuclear envelope [Term] id: DDPHENO:0001430 name: increased localization of a protein to the nuclear envelope def: "Increase in amount or accumulation of a protein in the nuclear envelope." [DDB:pf] is_a: DDPHENO:0001427 ! aberrant localization of a protein to the nuclear envelope [Term] id: DDPHENO:0001431 name: aberrant tip formation def: "Deviation from the normal, usual, or expected events during tip formation." [DDB:pf] is_a: DDPHENO:0000154 ! aberrant development [Term] id: DDPHENO:0001432 name: delayed sporulation is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0001433 name: aberrant gamma-aminobutyric acid signaling pathway def: "Deviation from the normal, usual, or expected events during the gamma-aminobutyric acid signaling pathway." [DDB:pf] synonym: "aberrant GABA signaling pathway" EXACT [] is_a: DDPHENO:0001118 ! aberrant signal transduction [Term] id: DDPHENO:0001434 name: abolished histone deacetylase activity def: "Complete absence of histone deacetylase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001435 name: decreased histone deacetylase activity def: "Reduction in extent, amount, or degree of histone deacetylase activity." [DDB:pg] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001436 name: increased histone deacetylase activity def: "Increase in extent, amount, or degree of histone deacetylase activity." [DDB:pg] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001437 name: aberrant necrotic cell death def: "Deviation from the normal, usual, or expected events during necrotic cell death." [DDB:pf] is_a: DDPHENO:0001267 ! aberrant cell death [Term] id: DDPHENO:0001438 name: abolished necrotic cell death def: "Complete inability for necrotic cell death." [DDB:pf] is_a: DDPHENO:0001437 ! aberrant necrotic cell death [Term] id: DDPHENO:0001439 name: decreased necrotic cell death def: "Reduction in extent, amount, or degree of necrotic cell death." [DDB:pf] is_a: DDPHENO:0001437 ! aberrant necrotic cell death [Term] id: DDPHENO:0001440 name: increased necrotic cell death def: "Increase in extent, amount, or degree of necrotic cell death." [DDB:pf] is_a: DDPHENO:0001437 ! aberrant necrotic cell death [Term] id: DDPHENO:0001441 name: aberrant cell fate commitment def: "Deviation from the normal, usual, or expected events when committing cells for a specific fate in their normal environment." [DDB:pf] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001442 name: decreased cell fate commitment def: "Reduction in extent, amount, or degree when committing cells for a specific fate in their normal environment." [DDB:pf] is_a: DDPHENO:0001441 ! aberrant cell fate commitment [Term] id: DDPHENO:0001443 name: aberrant cell fate determination def: "Deviation from the normal, usual, or expected events when committing cells for a specific fate regardless of its environment." [DDB:pf] is_a: DDPHENO:0001441 ! aberrant cell fate commitment [Term] id: DDPHENO:0001444 name: decreased cell fate determination def: "Reduction in extent, amount, or degree when committing cells for a specific fate regardless of its environment." [DDB:pf] is_a: DDPHENO:0001443 ! aberrant cell fate determination [Term] id: DDPHENO:0001445 name: aberrant F-actin polymerization def: "Complete inability to polymerize actin into F-actin." [DDB:pf] is_a: DDPHENO:0000151 ! aberrant F-actin organization created_by: pfey creation_date: 2010-02-03T05:27:42Z [Term] id: DDPHENO:0001446 name: aberrant F-actin depolymerization def: "Complete inability to depolymerize actin into F-actin." [DDB:pf] xref: XX: is_a: DDPHENO:0000151 ! aberrant F-actin organization created_by: pfey creation_date: 2010-02-03T05:54:09Z [Term] id: DDPHENO:0001447 name: abolished F-actin depolymerization def: "Complete inability to depolymerize actin into F-actin." [DDB:pf] is_a: DDPHENO:0001446 ! aberrant F-actin depolymerization created_by: pfey creation_date: 2010-02-03T05:57:47Z [Term] id: DDPHENO:0001448 name: decreased F-actin depolymerization def: "Reduction in extent, amount, or degree of F-actin depolymerization." [DDB:pf] is_a: DDPHENO:0001446 ! aberrant F-actin depolymerization created_by: pfey creation_date: 2010-02-03T05:59:24Z [Term] id: DDPHENO:0001449 name: increased F-actin depolymerization def: "Increase in extent, amount, or degree of F-actin depolymerization." [DDB:pf] is_a: DDPHENO:0001446 ! aberrant F-actin depolymerization created_by: pfey creation_date: 2010-02-03T06:00:17Z [Term] id: DDPHENO:0001450 name: abolished protein phosphorylation def: "Complete inability for protein phosphorylation." [DDB:pf] is_a: DDPHENO:0001342 ! aberrant protein phosphorylation created_by: pfey creation_date: 2010-02-16T04:04:04Z [Term] id: DDPHENO:0001451 name: abolished phosphorylation of actin def: "Complete inability for actin phosphorylation." [DDB:pf] is_a: DDPHENO:0001450 ! abolished protein phosphorylation created_by: pfey creation_date: 2010-02-16T04:06:48Z [Term] id: DDPHENO:0001452 name: abolished protein serine phosphorylation def: "Complete inability for protein serine phosphorylation." [DDB:pf] is_a: DDPHENO:0001450 ! abolished protein phosphorylation created_by: pfey creation_date: 2010-02-16T04:07:35Z [Term] id: DDPHENO:0001453 name: abolished protein threonine phosphorylation def: "Complete inability for protein threonine phosphorylation." [DDB:pf] is_a: DDPHENO:0001450 ! abolished protein phosphorylation created_by: pfey creation_date: 2010-02-16T04:08:34Z [Term] id: DDPHENO:0001454 name: abolished protein tyrosine phosphorylation def: "Complete inability for protein tyrosine phosphorylation." [DDB:pf] is_a: DDPHENO:0001450 ! abolished protein phosphorylation created_by: pfey creation_date: 2010-02-16T04:08:50Z [Term] id: DDPHENO:0001455 name: aberrant intracellular pH level def: "Deviation from the normal, usual, or expected regulation of the intracellular pH level." [DDB:pf] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis created_by: pfey creation_date: 2010-02-19T11:12:47Z [Term] id: DDPHENO:0010000 name: Dicty Phenotypes [Term] id: ID:0000000 name: increased spindle stabilization def: "Increase in spindle stabilization." [DD:pg] is_a: ID:0000001 ! aberrant spindle stabilization created_by: Pascale creation_date: 2010-02-02T01:53:33Z [Term] id: ID:0000001 name: aberrant spindle stabilization def: "Deviation from the normal, usual, or expected during spindle stabilization." [DDB:pg] is_a: DDPHENO:0001419 ! aberrant spindle organization created_by: Pascale creation_date: 2010-02-02T01:54:26Z [Term] id: ID:0000002 name: delayed spindle elongation def: "Late onset or slower progression of the spindle elongation." [DDB:pg] is_a: ID:0000003 ! aberrant spindle elongation created_by: Pascale creation_date: 2010-02-02T01:58:01Z [Term] id: ID:0000003 name: aberrant spindle elongation def: "Deviation from the normal, usual, or expected during spindle elongation." [DDB:pg] is_a: DDPHENO:0001419 ! aberrant spindle organization created_by: Pascale creation_date: 2010-02-02T02:00:10Z BACK TO TOP - BACK TO DOWNLOADS INDEX |
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