dictyBase Literature
Page Contents: Abstract | Summary Chart
Ogawa, S., Yoshino, R., Angata, K., Iwamoto, M., Pi, M., Kuroe, K., Matsuo, K., Morio, T., Urushihara, H., Yanagisawa, K., Tanaka, Y., (2000) ' The mitochondrial DNA of Dictyostelium discoideum: complete sequence, gene content and genome organization. ' Mol Gen Genet 263 514-9
  
 
Abstract:We present an overview of the gene content and organization of the mitochondrial genome of Dictyostelium discoideum. The mitochondria genome consists of 55,564 bp with an A + T content of 72.6%. The identified genes include those for two ribosomal RNAs (rn1 and rns), 18 tRNAs, ten subunits of the NADH dehydrogenase complex (nad1, 2, 3, 4, 4L, 5, 6, 7, 9 and 11), apocytochrome b (cytb), three subunits of the cytochrome oxidase (cox1/2 and 3), four subunits of the ATP synthase complex (atp1, 6, 8 and 9), 15 ribosomal proteins, and five other ORFs, excluding intronic ORFs. Notable features of D. discoideum mtDNA include the following. (1) All genes are encoded on the same strand of the DNA and a universal genetic code is used. (2) The cox1 gene has no termination codon and is fused to the downstream cox2 gene. The 13 genes for ribosomal proteins and four ORF genes form a cluster 15.4 kb long with several gene overlaps. (3) The number of tRNAs encoded in the genome is not sufficient to support the synthesis of mitochondrial protein. (4) In total, five group I introns reside in rnl and cox1/2, and three of those in cox1/2 contain four free-standing ORFs. We compare the genome to other sequenced mitochondrial genomes, particularly that of Acanthamoeba castellanii.
Status: Published Type: Journal article Source: PUBMED PubMed ID: 10821186
 
Genes addressed in this paper
DidioMp05 DidioMp21 DidioMp26 DidioMp27 DidioMp30 DidioMp35 DidioMp36 ai2a
Topics in this paper
Genome-wide Analysis X X X X X X X X
Non-mammalian Gene Related X X X X X X X X
DNA/RNA Sequence Features X X X X X X X X


Genes addressed in this paper
ai2b ai3 ai4 atp1 atp4 atp6 atp8 atp9
Topics in this paper
Genome-wide Analysis X X X X X X X X
Non-mammalian Gene Related X X X X X X X X
DNA/RNA Sequence Features X X X X X X X X


Genes addressed in this paper
cox1/2 cox3 cytB mrpl11 mrpl14 mrpl16 mrpl2 mrpl6
Topics in this paper
Genome-wide Analysis X X X X X X X X
Non-mammalian Gene Related X X X X X X X X
DNA/RNA Sequence Features X X X X X X X X


Genes addressed in this paper
mrps12 mrps13 mrps14 mrps19 mrps2 mrps4 mrps7 mrps8
Topics in this paper
Genome-wide Analysis X X X X X X X X
Non-mammalian Gene Related X X X X X X X X
DNA/RNA Sequence Features X X X X X X X X


Genes addressed in this paper
nad1 nad11 nad2 nad3 nad4 nad4L nad5 nad6
Topics in this paper
Genome-wide Analysis X X X X X X X X
Non-mammalian Gene Related X X X X X X X X
DNA/RNA Sequence Features X X X X X X X X


Genes addressed in this paper
nad7 nad9 rnlA tRNA-Arg-UCU-1 tRNA-Asn-GUU-1 tRNA-Gln-UUG-1 tRNA-Glu-UUC-1 tRNA-His-GUG-1
Topics in this paper
Genome-wide Analysis X X X X X X X X
Non-mammalian Gene Related X X X X X X X X
DNA/RNA Sequence Features X X X X X X X X


Genes addressed in this paper
tRNA-Ile-GAU-1 tRNA-Ile-GAU-2 tRNA-Lys-UUU-1 tRNA-Met-CAU-1 tRNA-Met-CAU-2 tRNA-Phe-GAA-1 tRNA-Pro-UGG-1 tRNA-Tyr-GUA-1
Topics in this paper
Genome-wide Analysis X X X X X X X X
Non-mammalian Gene Related X X X X X X X X
DNA/RNA Sequence Features X X X X X X X X