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Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains Null - Overexpression - Multiple - Other - Developmental

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Strain ID Strain Descriptor Associated gene(s) Strain Name(s) Phenotypes
DBS0252824dstA-/GFP: dstA(237-707): ORF+/[act15]: 2C2C, dstADd-STATa, STATaaberrant fruiting body morphology
DBS02386015NT-5NTdelayed tip formation, multiple tips in culminant, multiple tips in mound
DBS0252823dstA-/GFP: dstA(237-707): ORF+/[act15]: 7E7E, dstA, hssBDd-STATa, NK20-like, STATawild type
HAD186aarA-aarAaaraberrant fruiting body morphology, decreased sporulation
DBS0264145V10185abcA5aberrant cAMP wave formation, aberrant culmination, aberrant vegetative growth, wild type
DBS0264303V10460abcC9abcC11aberrant slug migration
DBS0236539abcG2-/abcG18-abcG18, abcG2mdrA, mdrA1, mdrA2abolished growth, decreased growth rate, decreased rate of endocytosis
DBS0236540abcG2-/abcG18-/rtoA-abcG18, abcG2, rtoARatioA, mdrA, mdrA1, mdrA2abolished growth, decreased growth rate
DBS0266687abiA-abiAAbi2aberrant cytokinesis, aberrant protein localization, decreased chemotaxis to folate, decreased growth rate, decreased protein level
DBS0266688abiA-abiAAbi2aberrant protein localization
DBS0266689abiA-/scrA-abiA, scrAAbi2, SCAR, WAVEdecreased cell motility, decreased cell size
DBS0235456abpA-/abpC-abpA, abpCABP-120, ABP120, FLN, actnA, ddFLN, gelAaberrant development, aberrant response to hyperosmotic stress, decreased cell motility, decreased growth rate, decreased phagocytosis
DBS0235425abpB-/fimA-abpB, fimAABP34, fim, p30, p67, plastindecreased cell size, decreased sporulation, small fruiting body
HG1270abpC-abpCABP-120, ABP120, FLN, ddFLN, gelAaberrant phototaxis
DBS0235426abpC-/[act15]: abpCabpCABP-120, ABP120, FLN, ddFLN, gelAwild type
DBS0236077abpC-abpCABP-120, ABP120, FLN, ddFLN, gelAaberrant phototaxis, aberrant thermotaxis
DBS0237938abpC-/[act15]: GFP: abpC(9-148)abpCABP-120, ABP120, FLN, ddFLN, gelAaberrant phototaxis
DBS0237941abpC-/[act15]: abpC(1-739): GFPabpCABP-120, ABP120, FLN, ddFLN, gelAaberrant phototaxis
DBS0237945abpC-/[act15]: abpC(1-348: 449-857): GFPabpCABP-120, ABP120, FLN, ddFLN, gelAaberrant F-actin organization, aberrant phototaxis
DBS0237946abpC-/[act15]: abpC(1-556: 644-857): GFPabpCABP-120, ABP120, FLN, ddFLN, gelAaberrant F-actin organization, aberrant phototaxis
DBS0237948abpC-/[ecmA]: abpC: GFPabpCABP-120, ABP120, FLN, ddFLN, gelAwild type
DBS0237949abpC-/[cotB]: abpC: GFPabpCABP-120, ABP120, FLN, ddFLN, gelAaberrant phototaxis
DBS0264853V30371abpCABP-120, ABP120, FLN, ddFLN, gelAaberrant aggregation, aberrant culmination, abolished culmination, abolished slug migration
DBS0235427abpD-abpDaberrant development, decreased cell-cell adhesion, decreased spore viability, delayed development
DBS0235428abpE-abpEDabp1increased lateral pseudopod formation
DBS0237096[act15]: abpEabpEDabp1aberrant aggregation, decreased cell motility, delayed development, increased lateral pseudopod formation, small fruiting body
DBS0237114[act15]: GFP: abpE(413-481)abpEDabp1increased lateral pseudopod formation
DBS0235430acaA-acaAACAaberrant F-actin organization, aberrant cell morphology, decreased chemotaxis rate, increased lateral pseudopod formation
DBS0235562acaA-acaAACAabolished aggregation
TL177acbA-acbAabolished SDF production, abolished sorting to prestalk region, decreased spore viability
AK1211acbA-/tagA-acbA, tagAincreased prestalk B cell differentiation
DBS0235440acgA-acgAACGprecocious spore germination
DBS0237788acgA-acgAACGdecreased gene expression, decreased prespore cell differentiation
DBS0237786acrA-/[act15]: acgA(1-401)acgA, acrAACB, ACG, ACR, DG1100decreased gene expression, decreased prespore cell differentiation, decreased sporulation
DBS0237790acgA-/[acrA]: lacZacgA, acrAACB, ACG, ACR, DG1100mislocalized gene expression
DG1100acrA-acrAACB, ACR, DG1100decreased gene expression, decreased sporulation, increased stalk length, spores inviable
DBS0264185V10225acrAACB, ACR, DG1100aberrant cAMP wave formation, aberrant culmination, aberrant slug migration
DBS0237116[act15]: GFP: act15act15act3a, actin15, actinA1, actinIII-12, actinIII-12/A1aberrant cell morphology, abolished cytokinesis, decreased cell motility
DBS0264700V30213act9actin9aberrant culmination, wild type
DBS0265573V31157act9actin9wild type
DBS0265066V30606adkBADKwild type
DBS0264268V10321adprt1BPARP3, pARTdaberrant cAMP wave formation, wild type
DBS0265247V30814adprt1BPARP3, pARTdwild type
DBS0264324V10514adprt3TNKS, pARTbaberrant cAMP wave formation, aberrant streaming
DBS0238203adrm1-adrm1-1adrm1aberrant response to nutrients, precocious development, precocious gene expression
DBS0235457ahhA-ahhAaberrant culminant morphology
DBS0264607V30110alg9aberrant cAMP wave formation, aberrant vegetative growth, wild type
DBS0264662V30165alg9aberrant cAMP wave formation, aberrant culmination, aberrant streaming, wild type
DBS0238600alp-alpaplAwild type
DBS0235473alrA-/[act15]: alrAalrAwild type
DBS0235513alrA-alrAdecreased cell motility, decreased cytosolic glucose level, decreased extracellular counting factor component(s) level, increased aggregate size
DBS0235474alxA-alxAALIX, DdAlix, alxaberrant fruiting body morphology, decreased growth rate, development arrests at loose aggregate stage
DBS0235475alxA-alxAALIX, DdAlix, alxaberrant fruiting body morphology, abolished sporulation, decreased gene expression, development arrests at mound stage
DBS0235476alxA-/[act15]: alxA(1-596): myc2alxAALIX, DdAlix, alxwild type
DBS0235477alxA-/[act15]: alxA(1-697): myc2alxAALIX, DdAlix, alxwild type
DBS0235478alxA-/[act15]: alxA(155-697): myc2alxAALIX, DdAlix, alxaberrant fruiting body morphology
DBS0235479alxA-/[act15]: alxA(293-697): myc2alxAALIX, DdAlix, alxaberrant fruiting body morphology
DBS0235480alxA-/[act15]: alxA(460-794): myc2alxAALIX, DdAlix, alxaberrant fruiting body morphology
DBS0235481alxA-/[act15]: alxA(D310A/N311A)alxAALIX, DdAlix, alxwild type
DBS0235482alxA-/[act15]: alxA(Q181E/Q183)alxAALIX, DdAlix, alxwild type
DBS0235483alxA-/[act15]: alxA(S700A/S704A/S708A)alxAALIX, DdAlix, alxwild type
DBS0235484alxA-/[act15]: alxA(S700D/S704D/S708D)alxAALIX, DdAlix, alxwild type
DBS0235485alxA-/[act15]: alxA(Y315D)alxAALIX, DdAlix, alxwild type
DBS0235486alxA-/[act15]: alxA(Y315F)alxAALIX, DdAlix, alxwild type
DBS0235487alxA-/[act15]: alxA: myc2alxAALIX, DdAlix, alxwild type
DBS0235488alxA-/[act15]: FLAG: alxAalxAALIX, DdAlix, alxdelayed development
DBS0235489alyA-alyAincreased phagocytosis
DG1114amdA-amdAdecreased spore viability, increased prestalk A cell differentiation, translucent sorus
HM1158amdA-amdAdecreased sporulation, increased aspidocyte differentiation, small fruiting body
DBS0264246V10286amdAaberrant culmination, wild type
DBS0235490amiB-amiBabolished aggregation
DBS0235491amiB-amiBabolished aggregation, abolished down-regulation of growth phase genes, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis to cAMP, decreased gene expression
DBS0235493ampA-ampAD11, pegAdecreased prestalk cell differentiation, delayed development, delayed gene expression, delayed tip formation, increased cell-cell adhesion, increased cell-substrate adhesion, mislocalized gene expression, precocious gene expression
BS155amtA-amtAdecreased aggregate size, decreased slug migration, increased growth rate, small fruiting body
BS165amtA-/amtC-amtA, amtCaberrant protein localization, aberrant slug migration, delayed gene expression
BS154amtC-amtCaberrant fruiting body morphology, aberrant protein localization, decreased gene expression, delayed culmination, development arrests at slug stage, mislocalized gene expression
DBS0235501amtC-/[act15]: cudAamtC, cudAdelayed culmination
DBS0235502amtC-/[ecmA]: cudAamtC, cudAdelayed culmination
DBS0235503amtC-/[pspA]: cudAamtC, cudAdevelopment arrests at slug stage
BS163amtC-/dhkC-amtC, dhkCmislocalized gene expression, wild type
DBS0236890amtC-/regA-amtC, regADG1030, DdPDE2, pde2precocious sporulation
DBS0235505apm1-apm1aberrant contractile vacuole organization and biogenesis, aberrant endosome morphology, aberrant response to hypo-osmotic stress, decreased growth rate, decreased spore germination, decreased stalk width, delayed development
DBS0235507apm3-apm3aberrant endosome morphology
DBS0235508apm4-apm4wild type
DBS0235509aprA-aprA60T, Ncf60aberrant cytokinesis, aberrant fruiting body morphology, decreased spore viability, decreased sporulation, increased aggregate size, increased growth rate
DBS0235510aprA-/[act15]: aprAaprA60T, Ncf60aberrant fruiting body morphology, decreased growth rate
HM2245arcB(I191L/D197Y/K206V/A213V/F223L/P224S/ E232G/I237T/H245L/S250S)arcBARPC2, Arc35, arpE, p34-Arcdecreased F-actin polymerization, decreased cell motility, decreased chemotaxis rate, decreased growth rate, decreased pseudopod formation
DBS0238412[inviable]arcBarcBARPC2, Arc35, arpE, p34-Arcinviable
DBS0235511arkA-arkAARCK-1aberrant fruiting body morphology, increased gene expression
DBS0235512arkA-/[arkA]: arkA: myc2arkAARCK-1aberrant aggregation
DBS0237221[arkA]: arkA: myc2arkAARCK-1aberrant aggregation
DBS0236948spnA-/arkA-arkA, spnAARCK-1, Spalten, Spndecreased gene expression, decreased stalk length, delayed gene expression, increased sorus size
MZ10arpB-/[act15]: myc: arpBarpBARP2wild type
DJK45arpB+/arpB-arpBARP2wild type
DMZ10arpB+/arpB-/[act15]: myc: arpBarpBARP2wild type
HM2191[arpB]: arpB: GFParpBARP2decreased F-actin polymerization, decreased cell motility, decreased cell-substrate adhesion, decreased chemotaxis rate, decreased growth rate, increased bleb formation
DBS0238407[inviable]arpB-arpBARP2inviable
DBS0235514aslA-aslAwild type
HR131atg1-atg1APG1aberrant cellular response to nitrogen starvation, abolished aggregation, abolished macroautophagy, abolished sporulation, abolished stalk cell differentiation, decreased growth rate in suspension, decreased growth rate on bacterial plates, increased number of autophagosomes
DBS0236304atg1-atg1APG1aberrant macroautophagy, abolished autophagic vacuole formation
DBS0236305atg1-atg1APG1aberrant macroautophagy, abolished autophagic vacuole formation
DBS0238085atg1-/[act15]: atg1atg1APG1wild type
DBS0238086[act15]: atg1atg1APG1wild type
DBS0238087atg1-/[act15]: atg1(K36A)atg1APG1aberrant cellular response to nitrogen starvation, abolished aggregation
DBS0238088[act15]: atg1(K36A)atg1APG1aberrant cellular response to nitrogen starvation, abolished aggregation, abolished macroautophagy, increased number of autophagosomes
DBS0238089atg1-/[act15]: atg1(K36A/1-628)atg1APG1aberrant cellular response to nitrogen starvation, abolished aggregation
DBS0238090[act15]: atg1(K36A/1-628)atg1APG1wild type
DBS0238091[act15]: atg1(1-628)atg1APG1wild type
DBS0238092atg1-/[act15]: atg1(1-628)atg1APG1aberrant cellular response to nitrogen starvation, abolished aggregation
DBS0238093atg1-/[act15]: atg1(P138S)atg1APG1abolished aggregation
DBS0266655atg1-/iplA-atg1, iplAAPG1decreased non-apoptotic programmed cell death
DBS0252632atg1-/pcp-atg1, pcpAPG1abolished autophagic vacuole formation
HR75atg5-atg5APG5aberrant cellular response to nitrogen starvation, aberrant macroautophagy, abolished aggregation, abolished sporulation, multiple tips
HR174atg6-atg6AAPG6, atg6aberrant cellular response to nitrogen starvation, aberrant macroautophagy, decreased sporulation, decreased stalk length, multiple tips, small fruiting body
HR79atg7-atg7APG7aberrant cellular response to nitrogen starvation, aberrant macroautophagy, abolished sporulation, multiple tips
HR141atg8-atg8APG8aberrant cellular response to nitrogen starvation, aberrant macroautophagy, aberrant spore morphology, decreased sporulation, multiple tips, small fruiting body
DBS0265497V31075BC4V2_0_00042aberrant cAMP wave formation, aberrant culmination, aberrant streaming, abolished aggregation, abolished slug migration, wild type
DBS0265890V31501BC4V2_0_00042aberrant cAMP wave formation, aberrant culmination, wild type
DBS0264131V10170BC4V2_0_00063aberrant cAMP wave formation, aberrant culmination, aberrant slug migration, abolished culmination
DBS0264575V30069BC4V2_0_00853aberrant cAMP wave formation, aberrant streaming
DBS0264079V10117BC4V2_0_01073aberrant slug migration, abolished culmination
DBS0264195V10235BC4V2_0_01533wild type
DBS0265279V30846BC4V2_0_01593wild type
DBS0265688V31281BC4V2_0_01750aberrant cAMP wave formation, aberrant culmination, aberrant streaming, wild type
DBS0264763V30278BC4V2_0_02006wild type
DBS0264684V30188BC5V2_0_00252aberrant cAMP wave formation, aberrant streaming, wild type
DBS0265520V31102BC5V2_0_00345wild type
DBS0264992V30522BC5V2_0_00398aberrant cAMP wave formation, aberrant streaming, wild type
DBS0264135V10174BC5V2_0_00679aberrant cAMP wave formation, aberrant culmination, aberrant slug migration, aberrant streaming, aberrant vegetative growth
DBS0264160V10200BC5V2_0_01044aberrant cAMP wave formation, aberrant culmination, aberrant slug migration
DBS0264634V30137BC5V2_0_01129wild type
DBS0265198V30758BC5V2_0_01131wild type
DBS0266000V31649BC5V2_0_01570aberrant culmination, wild type
DBS0264297V10445BC5V2_0_01781aberrant slug migration
DBS0266190V31853BC5V2_0_01793aberrant aggregation, aberrant cAMP wave formation, aberrant culmination, aberrant slug migration
DBS0264288V10432BC5V2_0_01928wild type
DBS0265049V30582BEC6V2_0_00285wild type
DBS0264334V10534BEC6V2_0_00310aberrant culmination, wild type
DBS0264073V10108BEC6V2_0_00491aberrant vegetative growth, abolished aggregation, abolished cAMP wave formation, abolished culmination, abolished slug migration, abolished streaming
DBS0264081V10119BEC6V2_0_00495wild type
DBS0264227V10267BEC6V2_0_00528aberrant aggregation, aberrant streaming
DBS0264176V10216BEC6V2_0_00907aberrant vegetative growth, wild type
DBS0264773V30288BEC6V2_0_01091aberrant cAMP wave formation, aberrant streaming, wild type
DBS0264087V10125BEC6V2_0_01092aberrant cAMP wave formation, aberrant slug migration
DBS0264216V10256BEC6V2_0_01092aberrant cAMP wave formation, aberrant culmination, aberrant streaming, abolished slug migration
TL97cadA-cadACAD1, DdCAD-1, GP24, rcdD, veg102decreased sporulation, delayed culmination, increased prestalk cell differentiation, multiple tips
DBS0237097[act15]: cak1: myccak1CK1, DdCK1decreased sensitivity to DNA-damaging agents
DBS0237256[inviable]cak1cak1CK1, DdCK1inviable
DBS0237273[AS]calAcalAabolished cytokinesis
DBS0237204[act6]: canAcanACNA, PP2Bwild type
DBS0235563capB-truncatedcapBdecreased growth rate, delayed development
DG1056lipB-captCDG1056, lipBaberrant fruiting body morphology
DBS0252732[act15]: carA(I104C)carA-1, carA-2cAR1, carA, carA1, carA2decreased MAP kinase activation
DBS0252733[act15]: carA(I104W)carA-1, carA-2cAR1, carA, carA1, carA2increased cAMP binding
DBS0252734[act15]: carA(I104P)carA-1, carA-2cAR1, carA, carA1, carA2decreased MAP kinase activation
DBS0252735[act15]: carA(I104T)carA-1, carA-2cAR1, carA, carA1, carA2aberrant cAMP wave formation, increased cAMP binding
DBS0252737[act15]: carA(I104A)carA-1, carA-2cAR1, carA, carA1, carA2decreased cAMP binding
DBS0252738[act15]: carA(I104G)carA-1, carA-2cAR1, carA, carA1, carA2decreased MAP kinase activation, increased cAMP binding
DBS0252740[act15]: carA(I104D)carA-1, carA-2cAR1, carA, carA1, carA2aberrant cAMP wave formation, decreased MAP kinase activation, delayed aggregation, increased cAMP binding
DBS0252741[act15]: carA(I104F)carA-1, carA-2cAR1, carA, carA1, carA2decreased MAP kinase activation, increased cAMP binding
DBS0252742[act15]: carA(I104M)carA-1, carA-2cAR1, carA, carA1, carA2increased cAMP binding
DBS0252743[act15]: carA(I104S)carA-1, carA-2cAR1, carA, carA1, carA2aberrant cAMP wave formation, decreased MAP kinase activation, increased cAMP binding
DBS0252744[act15]: carA(I104E)carA-1, carA-2cAR1, carA, carA1, carA2aberrant cAMP wave formation, delayed aggregation, increased cAMP binding
DBS0252745[act15]: carA(I104Q)carA-1, carA-2cAR1, carA, carA1, carA2abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0252746[act15]: carA(I104N)carA-1, carA-2cAR1, carA, carA1, carA2abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0252747[act15]: carA(I104H)carA-1, carA-2cAR1, carA, carA1, carA2abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0252748[act15]: carA(I104Y)carA-1, carA-2cAR1, carA, carA1, carA2aberrant cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0252749[act15]: carA(I104K)carA-1, carA-2cAR1, carA, carA1, carA2abolished aggregation, abolished cAMP wave formation, decreased MAP kinase activation, increased cAMP binding
DBS0252750[act15]: carA(I104R)carA-1, carA-2cAR1, carA, carA1, carA2abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0266697rasC-/rasG-/[act15]: carAcarA-1, carA-2, rasC, rasGcAR1, carA, carA1, carA2, ddRASGabolished activation of Rap GTPase activity, abolished cAMP-induced cGMP pulse, abolished chemotaxis to cAMP, abolished growth, abolished protein kinase B activation, decreased activation of adenylate cyclase, decreased growth rate
RI4carA-/carC-carA-1, carCcAR1, cAR3, carA, carA1abolished aggregation, decreased cAMP-induced cGMP pulse, decreased chemoattractant-mediated F-actin polymerization
DBS0235570carB-carBcAR2development arrests at mound stage
DBS0235568car4-carDcAR4aberrant fruiting body morphology, decreased gene expression, increased gene expression
DBS0235573carmil-carmildecreased aggregate size, decreased basal F-actin level, decreased growth rate, decreased pinocytosis
DBS0235574catB-catBdelayed development, spores hypersensitive to H2O2 (peroxide)
DBS0236444JH.DcbfACMBF, cbfabolished aggregation, abolished gene expression, decreased gene expression, decreased growth rate, decreased stalk width, increased cell size, increased phagocytosis, increased pinocytosis, small fruiting body
DBS0264175V10215cbfBwild type
HC423cbpA-cbpACBP1decreased cell motility, delayed aggregation, increased aggregate size
DBS0235594CHE10cbpCCBP3decreased aggregate size, decreased slug migration, delayed culmination, precocious aggregation, small fruiting body
DBS0235595CHI2cbpCCBP3increased slug migration
DBS0235575cbpJ-cbpJCBP10wild type
DBS0237098[act15]: cdk5(D144N)cdk5crp, crpAdecreased extracellular counting factor component(s) level, decreased growth rate, decreased phagocytosis, decreased pinocytosis, decreased sporulation, delayed aggregation, increased aggregate size, increased extracellular counting factor component(s) level, increased intracellular counting factor component(s) level
DBS0235578cdk8-/[cdk8]: cdk8cdk8CDK, Ddcdk8wild type
DBS0235661cdk8-cdk8CDK, Ddcdk8abolished aggregation, decreased gene expression, mislocalized gene expression
DBS0237162[act15]: myc-cdk8cdk8CDK, Ddcdk8multiple tips
DBS0235584CF45-1-cf45-1decreased aggregate size, decreased cell motility, increased aggregate size, increased cell-cell adhesion, increased cytosolic glucose level
DBS0235585CF50-cf50-1cf50decreased extracellular counting factor component(s) level, increased aggregate size, increased cell-cell adhesion, increased gene expression
DBS0237099[act15]: cf60cf60aberrant regulation of aggregate size, increased number of aggregates
DBS0237222[AS]cf60cf60decreased number of aggregates, increased aggregate size
HO101chcA-chcAaberrant cytokinesis, decreased growth rate, decreased pinocytosis
HO103AX2/chcA-chcAaberrant fruiting body morphology, abolished cytokinesis, abolished gene expression, abolished growth in suspension, abolished sporulation, delayed aggregation
DBS0235589chcA-/[cotB]: lacZchcAmislocalized gene expression
DBS0235590chcA-/[ecmA]: lacZchcAmislocalized gene expression
DBS0235591chcA-/[ecmB]: lacZchcAmislocalized gene expression
DBS0235592chcA-/[pspA]: lacZchcAmislocalized gene expression
DBS0237223 (DBS0237699)[AS]chcAchcAaberrant vacuole organization and biogenesis, abolished aggregation, decreased cell size, decreased number of vacuoles, decreased pinocytosis, delayed response to hypo-osmotic stress
DBS0235588chcA-/[act15]: GFP: mhcAchcA, mhcAMHCdecreased positive regulation of GTPase activity
DBS0235596ChLim-ChLimincreased growth rate, increased phagocytosis
DBS0237274[OE]: chlimChLimdecreased growth rate, decreased phagocytosis, increased basal F-actin level
DBS0238350[inviable]cinCcinCEF2, Ef-2b, H6inviable
DBS0238351[tet]: [RNAi]cinCcinCEF2, Ef-2b, H6decreased growth rate, decreased translation, precocious aggregation
DBS0264464V11075cinCEF2, Ef-2b, H6aberrant culmination, wild type
DBS0235601clc-clcclcAaberrant fruiting body morphology, aberrant response to hypo-osmotic stress, abolished cytokinesis, abolished growth
DBS0235604clc-/[act15]: GFP-clc(146-194)clcclcAaberrant fruiting body morphology, abolished cytokinesis, wild type
DBS0235605clc-/[act15]: GFP-clc(85-124)clcclcAaberrant fruiting body morphology, abolished cytokinesis, wild type
DBS0235607clc-/[act15]GFP: clc(1-124)clcclcAaberrant fruiting body morphology, abolished cytokinesis, wild type
DBS0264390V10682clcDaberrant cAMP wave formation, abolished aggregation, abolished cAMP wave formation, abolished culmination, abolished slug migration, abolished streaming
DBS0235608clmA-clmAaberrant response to hypo-osmotic stress
DBS0237224[AS]cmfAcmfACMFabolished aggregation
DBS0235612CMFR1-cmfBCMFR1abolished aggregation, decreased gene expression
DBS0235409[RNAi]cnbAcnbACNBaberrant stalk cell differentiation, decreased gene expression, decreased stalk length, multiple tips in culminant
DBS0235613cnrB-cnrBwild type
DBS0265170V30724cnrKwild type
DBS0264480V11092cnrOwild type
HG1770cnxA-cnxAdecreased extracellular Ca2+ uptake, increased cytosolic Ca2+ response
HG1772crtA-/cnxA-cnxA, crtAdecreased extracellular Ca2+ uptake, decreased growth rate in suspension, decreased growth rate on bacterial plates, decreased phagocytosis, delayed response to cAMP, increased cytosolic Ca2+ response
DBS0237102[act15]: cofAcofADCOF1increased actin bundle formation, increased cell motility, increased membrane ruffling
DBS0237257[inviable]cofAcofADCOF1inviable
DBS0235615cofB-cofBDCOF2wild type
DBS0235616cofC-cofC-1DCOF3, cofCwild type
DG1016comB-comBDG1016, ORF1016abolished culmination
DBS0235617comB-comBDG1016, ORF1016abolished culmination
DBS0235618comC-comCaberrant aggregation, aberrant streaming
DBS0235619comD-comDabolished culmination
DBS0264126V10165comDaberrant aggregation, aberrant cAMP wave formation, aberrant culmination, abolished slug migration
DBS0235620comE-comEaberrant fruiting body morphology, translucent sorus
DBS0264125V10164comEaberrant culmination, aberrant slug migration, aberrant vegetative growth, abolished culmination
DBS0235622comG-comGALDHdevelopment arrests at mound stage, multiple tips
DBS0264188V10228comGALDHaberrant aggregation, aberrant cAMP wave formation, aberrant culmination, aberrant slug migration, aberrant streaming, aberrant vegetative growth, abolished culmination, abolished slug migration
DBS0235623comH-comHgtaBdevelopment arrests at mound stage
DBS0264106V10144comHgtaBaberrant aggregation, abolished culmination, abolished slug migration
HG1569corA-corAaberrant cell morphology, aberrant cytokinesis, decreased cell motility, decreased growth rate
HG1570corA-corAaberrant cell morphology, aberrant cytokinesis, decreased cell motility, decreased growth rate
HG1571corA-corAaberrant cell morphology, aberrant cytokinesis, decreased cell motility, decreased growth rate
TL55cotA-cotASP96aberrant spore coat morphology
TL53cotA-/cotB-cotA, cotBSP70, SP96aberrant spore coat morphology
TL56cotA-/cotB-/cotC-cotA, cotB, cotCSP60, SP70, SP96aberrant spore coat morphology
TL57cotA-/cotB-/cotC-cotA, cotB, cotCSP60, SP70, SP96aberrant spore coat morphology
DBS0236996TL26cotBSP70aberrant spore coat morphology
TL54cotB-/cotC-cotB, cotCSP60, SP70aberrant spore coat morphology
TL52cotC-cotCSP60aberrant spore coat morphology
HW07cotE(1-235)cotESP65aberrant spore coat morphology
DBS0238297cpnA-cpnAaberrant cytokinesis, aberrant fruiting body morphology, decreased culmination, decreased growth rate, delayed development, delayed response to hypo-osmotic stress
DBS0238320cpnA-/[act15]: GFP: cpnAcpnAdecreased culmination, delayed development, delayed response to hypo-osmotic stress
DBS0235627crlA-crlAdecreased sorting to prestalk region, delayed tip formation, increased aggregate size, increased growth rate
DBS0235628crlA-/[crlA]: crlAcrlAincreased aggregate size
DBS0237091yakA-/[crlA]: crlAcrlA, yakAdagBabolished growth
DBS0235629crlB-crlBwild type
DBS0235630crlC-crlCwild type
HG1768crtA-crtAdecreased extracellular Ca2+ uptake, increased cytosolic Ca2+ response
DBS0235633crtf-CRTFabolished aggregation, abolished sporulation, decreased gene expression
TL73csaA-/csbA-/csbC-/csbC-csaA, csbA, csbB, csbCcsA, gp80aberrant culminant morphology
DBS0236982TL114csbAabolished aggregation, decreased cell-cell adhesion
TL72csbA-/csbB-/csbC-csbA, csbB, csbCaberrant culminant morphology
WTC127cshA-cshAdecreased growth rate, decreased phagocytosis, delayed aggregation, development arrests at loose aggregate stage
DBS0237258[inviable]csn2CSN2inviable
DBS0235634csn5-KDCSN5decreased growth rate
DBS0237259[inviable]csn5CSN5inviable
DBS0264182V10222ctaAwild type
DBS0235624ctnA-ctnAcountindecreased basal F-actin level, decreased cAMP-induced cAMP pulse, decreased myosin II assembly, decreased protein level, increased GTP-gamma-S-stimulated guanylyl cyclase activity, increased aggregate size, increased cAMP-induced cGMP pulse, increased cell motility, increased cell-cell adhesion, increased cytosolic glucose level
DBS0236940smlA/ctnActnA, smlAcountinincreased cell-cell adhesion
DBS0235636ctnB-ctnBcountin2decreased gene expression, increased number of aggregates, small fruiting body
DG1071ctr9-ctr9DG1071aberrant fruiting body morphology
DG1058ctrA-ctrADG1058small fruiting body
DBS0264190V10230ctrADG1058aberrant aggregation, aberrant culmination, aberrant slug migration
HS1151ctxA-ctxAaberrant cytokinesis, decreased growth rate
DBS0235598ctxA-ctxAaberrant cell morphology, aberrant cytokinesis
DBS0235599ctxA-/ctxB-ctxA, ctxBFPS1aberrant cell morphology, aberrant cytokinesis
DBS0237536ctxA-/[act15]: enlA(92-497)ctxA, enlAenlazin, fimB, fimbrin-2wild type
DBS0237568ctxA-/[RNAi]enlActxA, enlAenlazin, fimB, fimbrin-2wild type
DBS0237564mhcA-/[act15]: GFP: ctxA/[RNAi]enlActxA, enlA, mhcAMHC, enlazin, fimB, fimbrin-2aberrant cytokinesis, contractile ring contraction
DBS0235600ctxB-ctxBFPS1aberrant cell morphology, aberrant cytokinesis
DBS0235639cudA-cudAabolished sporulation, abolished stalk cell differentiation, decreased gene expression, development arrests at slug stage
DBS0235640culA-culAdevelopment arrests at tipped mound stage, multiple tips
DBS0235641culA-/[cotC]: culAculAdecreased sporulation, decreased stalk length, increased sorus size
DBS0235642culA-/[ecmA]: culAculAdecreased stalk length, increased sorus size
DBS0235643culA-/[pkaC]pkaCculA, pkaCDdPK2, DdPK3, PK2, PK3, PKA, PKA-C, cAK, pkacatwild type
DBS0237225[AS]cupBcupBabolished aggregation
DBS0235651cybA-cybAp22phoxaberrant development, abolished sporulation
DBS0236745pefB-/cybA-cybA, pefBALG-2, DdPEF-2, alg-2B, alg2, alg2B, p22phox, pef2wild type
DBS0237237[dscB]: cycB(106-436)cycBclb1cell cycle arrest
DBS0264330V10529CYP508B1aberrant aggregation, aberrant cAMP wave formation, aberrant culmination, aberrant slug migration, aberrant streaming, abolished slug migration
AK108dagA-dagACRAC, synag7abolished activation of adenylate cyclase, abolished aggregation, abolished gene expression, decreased gene expression
DBS0235652dagA-/[act15]: dagAdagACRAC, synag7wild type
DBS0237104[act15]: dagAdagACRAC, synag7wild type
DBS0264065V00262dagACRAC, synag7abolished aggregation, abolished cAMP wave formation, abolished culmination, abolished slug migration, abolished streaming
DBS0264347V10567dagACRAC, synag7abolished aggregation, abolished cAMP wave formation, abolished culmination, abolished slug migration, abolished streaming
DBS0252637DAip1-DAip1AIP1, WRP2, rcdA, veg150, wdpAdecreased growth rate, decreased phagocytosis, decreased pinocytosis, delayed cytokinesis
DBS0235653darA-darAabolished aggregation, decreased aggregate size
TL127dcsA-dcsAaberrant spore coat morphology, abolished cellulose biosynthesis, abolished sporulation, abolished stalk cell differentiation, abolished stalk formation
TL128dcsA-/[act15]: dcsAdcsAwild type
DG1099dcsA-dcsAaberrant spore coat morphology, abolished cellulose biosynthesis, abolished sporulation, abolished stalk cell differentiation, abolished stalk formation
DG1128dcsA-dcsAaberrant spore coat morphology, abolished cellulose biosynthesis, abolished sporulation, abolished stalk formation
DBS0264169V10209dcsAabolished culmination
DBS0264189V10229dcsAaberrant cAMP wave formation, abolished culmination
DBS0266084V31738dcsAaberrant culmination, abolished culmination, wild type
DBS0237255[hairpin]dctdctaberrant cytokinesis
DBS0235659DD3-3-DD3-3decreased gene expression, precocious aggregation
DBS0266700Dd5P1-Dd5P1PI5P1wild type
DBS0266705Dd5P1-/Dd5P2-Dd5P1, Dd5P2PI5P1, PI5P2wild type
DBS0266704Dd5P1-/Dd5P3-Dd5P1, Dd5P3PI5P1, PI5P3wild type
DBS0235660Dd5P2-Dd5P2PI5P2increased basal F-actin level, wild type
DBS0266703Dd5P2-/Dd5P3-Dd5P2, Dd5P3PI5P2, PI5P3wild type
DBS0266702Dd5P3-Dd5P3PI5P3wild type
DBS0266692Dd5P4-Dd5P4PI5P4, RacGAPdecreased engulfment during phagocytosis, decreased growth rate, decreased phagocytosis, multiple tips in mound
DBS0266693Dd5P4-/[act15]: Dd5P4Dd5P4PI5P4, RacGAPwild type
DBS0266694Dd5P4-/[act15]: cat5P4Dd5P4PI5P4, RacGAPdecreased growth rate, multiple tips in mound
DBS0266695Dd5P4-/[act15]: GAP5P4Dd5P4PI5P4, RacGAPdecreased growth rate, multiple tips in mound
DBS0266719Dd5P4-/[act15]: Dd5P4: GFPDd5P4PI5P4, RacGAPwild type
DBS0266720Dd5P4-/[act15]: Hs-OCRLDd5P4PI5P4, RacGAPdecreased phagocytosis
DBS0266721Dd5P4-/[act15]: Hs-OCRL(D422A)Dd5P4PI5P4, RacGAPdecreased phagocytosis
DG1003DG1003-DG1003ORF1003aberrant culminant morphology
DG1007DG1007-DG1007ORF1007abolished culmination
DBS0264089V10127DG1037ORF1037aberrant cAMP wave formation, abolished aggregation, abolished cAMP wave formation, abolished culmination, abolished slug migration, abolished streaming
DBS0264159V10199DG1037ORF1037aberrant cAMP wave formation, aberrant streaming, abolished aggregation, abolished culmination, abolished slug migration
DG1039DG1039-DG1039ORF1039aberrant fruiting body morphology
DG1040DG1040-DG1040aberrant fruiting body morphology
DG1041DG1041-DG1041ORF1041aberrant fruiting body morphology
DG1054DG1054-DG1054aberrant fruiting body morphology
DG1060DG1060-DG1060ORF1060aberrant fruiting body morphology
DG1062DG1062-DG1062aberrant fruiting body morphology
DG1074DG1074-DG1074aberrant fruiting body morphology
DG1080DG1080-DG1080aberrant fruiting body morphology
DG1091DG1091-DG1091small fruiting body
DBS0264184V10224DG1091aberrant cAMP wave formation
DG1098DG1098-DG1098small fruiting body
DBS0264128V10167DG1098aberrant cAMP wave formation, wild type
DBS0264173V10213DG1098aberrant cAMP wave formation, aberrant streaming
DG1104DG1104-DG1104DG1104abolished aggregation
DBS0264233V10273DG1104DG1104aberrant vegetative growth, wild type
DG1105DG1105-DG1105abolished aggregation
DBS0264245V10285DG1105aberrant cAMP wave formation, aberrant vegetative growth, abolished aggregation, abolished culmination, abolished slug migration, abolished streaming
DG1106DG1106-DG1106abolished aggregation
DG1110DG1110-DG1110aberrant fruiting body morphology
DBS0264198V10238DG1110aberrant culmination, aberrant slug migration
DBS0264320V10495DG1110aberrant culmination, aberrant slug migration, wild type
DBS0265296V30863DG1110wild type
DG1112DG1112-DG1112RasGAPdecreased stalk width
DG1113DG1113-DG1113increased stalk length
DBS0264234V10274DG1113aberrant cAMP wave formation, aberrant culmination, aberrant vegetative growth
DBS0264272V10326DG1113aberrant cAMP wave formation, wild type
DG1122DG1122-DG1122aberrant fruiting body morphology
DBS0264235V10275DG1122aberrant cAMP wave formation, aberrant streaming, aberrant vegetative growth, abolished aggregation, abolished culmination, abolished slug migration, abolished streaming, wild type
DG1124DG1124-DG1124development arrests at loose aggregate stage
DBS0264164V10204DG1124aberrant aggregation, aberrant cAMP wave formation, aberrant streaming
DG2033DG2033-DG2033development arrests at mound stage
DG2044DG2044-DG2044development arrests at loose aggregate stage
DBS0235695dgkA-dgkAMHC-PKC, MHCKaberrant development, decreased chemotaxis rate, decreased spore viability, increased myosin II assembly
DBS0237105[act15]: dgkAdgkAMHC-PKC, MHCKdecreased chemotaxis rate, decreased myosin II assembly, development arrests at loose aggregate stage
AK299dhkA-dhkAaberrant fruiting body morphology, aberrant stalk morphogenesis, decreased sporulation, increased gene expression, increased sporulation in the presence of 8-Br-cAMP, mislocalized gene expression
DBS0264228V10268dhkAaberrant cAMP wave formation, aberrant culmination, aberrant slug migration, aberrant streaming
DBS0266022V31671dhkAaberrant culmination, aberrant slug migration
TL134dhkA-/dhkB-dhkA, dhkBabolished sporulation, decreased stalk width, increased stalk length
HR49dhkA-/fbxA-dhkA, fbxAchtAaberrant fruiting body morphology, decreased intracellular cAMP level, decreased sporulation
HR50dhkA-/fbxA-dhkA, fbxAchtAabolished culmination, decreased sporulation
HR51dhkA-/fbxA-dhkA, fbxAchtAaberrant fruiting body morphology, decreased sporulation
DBS0235704dhkB-dhkBprecocious spore germination
TL135dhkC-dhkCdecreased spore germination, precocious aggregation, precocious culmination, precocious development
DBS0237106[act15]: dhkC(394-661)dhkCincreased slug migration
DBS0264356V10588dhkCaberrant cAMP wave formation, aberrant streaming, wild type
DBS0235705[act15]: dhkK(D1125N)dhkKsmbA, sombreroaberrant cAMP signaling during aggregation, delayed development
DBS0235707[act15]: dhkK(H825Q)dhkKsmbA, sombreroprecocious development, small fruiting body
DBS0235709[act15]: dhkK(H825Q/D1125N)dhkKsmbA, sombreroaberrant slug migration, delayed culmination
DBS0235710dhkK-dhkKsmbA, sombreroaberrant slug migration, delayed culmination, delayed gene expression
DBS0235712dhkK-/[act15]: dhkK(D1125N)dhkKsmbA, sombreroaberrant fruiting body morphology
DBS0235716[act15]: dhkKdhkKsmbA, sombrerodevelopment arrests at mound stage, precocious aggregation
DBS0235706regA-/[act15]: dhkK(D1125N)dhkK, regADG1030, DdPDE2, pde2, smbA, sombreroaberrant fruiting body morphology, precocious development
DBS0235708regA-/[act15]: dhkK(H825Q)dhkK, regADG1030, DdPDE2, pde2, smbA, sombreroaberrant fruiting body morphology, precocious development
DBS0235714dhkK-/regA-dhkK, regADG1030, DdPDE2, pde2, smbA, sombreroprecocious development
DBS0264715V30229dhx35aberrant cAMP wave formation, wild type
DBS0237205[act6]: dia1dia1DIA-1delayed aggregation
DBS0237226[AS]dia1dia1DIA-1decreased gene expression, precocious aggregation
DBS0235719dia1-/[act6]: trap1dia1, trap1DIA-1, Dd-trap1aberrant aggregation, small fruiting body
dia2ASAX2/[act15]: [AS]dia2dia2development arrests at mound stage
DBS0264206V10246dicBaberrant cAMP wave formation, aberrant streaming
DBS0265126V30673dicBaberrant aggregation, aberrant cAMP wave formation, aberrant culmination, abolished slug migration
DBS0237294[RNAi]DidioMp05DidioMp05wild type
DBS0235895dimA-dimAbzpAaberrant fruiting body morphology, abolished prestalk cell differentiation, decreased prestalk O cell differentiation, increased prespore cell differentiation, increased slug size, long fingers, thin fingers
DBS0235899dimA-/dimB-dimA, dimBbzpA, bzpBincreased slug size, long fingers, thin fingers
DBS0235903dimB-/[act15]: dimA: GFPdimA, dimBbzpA, bzpBabolished nuclear protein localization
DBS0235901dimB-dimBbzpBabolished response to DIF
DBS0235902dimB-/[cotB]: lacZdimBbzpBincreased prespore cell differentiation
DBS0235904dimB-/[act15]: dimB: GFPdimBbzpBwild type
DBS0235906dimB-/[ecmAO]: lacZdimBbzpBdecreased prestalk O cell differentiation
DBS0235907dimB-/[ecmO]: lacZdimBbzpBaberrant prestalk cell differentiation
DBS0235913dmpA-dmpADmp1aberrant fruiting body morphology, aberrant streaming, decreased sporulation, decreased stalk cell differentiation, delayed development, translucent sorus
DBS0236855rasC-/dmpA-dmpA, rasCDmp1abolished streaming
HM1030dmtA-dmtAaberrant fruiting body morphology, abolished DIF production, abolished prestalk O cell differentation
DBS0235914dnapkcs-dnapkcsDNA-PKcs, PRKDCincreased sensitivity to DNA-damaging agents
DBS0235915dng1-dng1decreased growth rate, delayed aggregation
DBS0237107[act15]: dng1dng1aberrant cAMP signaling during aggregation, decreased growth rate, precocious aggregation
DBS0235916dnmA-dnmAaberrant culminant morphology, decreased cytosine methylation in genomic DNA, decreased sporulation, translucent sorus
DBS0235917dnmA-dnmAdecreased cytosine methylation in genomic DNA
DG2015docA-docADG1012, DG2016, timAdevelopment arrests at mound stage
DBS0235920dokA-dokAaberrant response to hyperosmotic stress, decreased sporulation, translucent sorus
HAD172dpoA-dpoAaberrant development
HAD200dpoA-dpoAaberrant development
HAD201dpoA-dpoAaberrant development
HAD202dpoA-dpoAaberrant development
HAD203dpoA-dpoAaberrant development
HAD205dpoA-/gskA-dpoA, gskAGSK-3, GSK3aberrant development
DBS0238474drkC-drkCrk3, vsk3decreased phagocytosis, decreased phagolysosome formation
DBS0238475drkC-/[act15]: drkC: YFPdrkCrk3, vsk3wild type
DBS0238511drkC-/[act15]: drkC(1-497): YFPdrkCrk3, vsk3decreased phagocytosis
DBS0238513drkC-/[act15]: drkC(K518R): YFPdrkCrk3, vsk3decreased phagocytosis
DBS0235924dscA-dscA-1, dscA-2dscAaberrant cell morphology
DBS0264444V11053dscA-1, dscA-2dscAaberrant vegetative growth, wild type
DBS0235925dstA-dstADd-STATa, STATaaberrant fruiting body morphology, abolished gene expression, abolished sorting to prestalk region, abolished stalk cell differentiation, decreased cell motility, decreased gene expression, delayed aggregation, increased gene expression, mislocalized gene expression
DBS0235926dstA-dstADd-STATa, STATaaberrant fruiting body morphology, abolished sorting to prestalk region, abolished stalk cell differentiation, decreased cell motility, delayed aggregation, mislocalized gene expression
DBS0235928dstA-/[act15]: dstAdstADd-STATa, STATawild type
DBS0235929dstA-/[cprB]: dstAdstADd-STATa, STATawild type
DBS0235930dstA-/[ecmAO]: dstAdstADd-STATa, STATawild type
DBS0238237dstA-/GFP: dstA(237-707): ORF+dstADd-STATa, STATaabolished culmination, decreased stalk length
DBS0266088V31742dstADd-STATa, STATaaberrant culmination, aberrant slug migration, abolished culmination
DBS0235927dstA-/dstB-dstA, dstBDd-STATa, Dd-STATb, STATa, STATbwild type
DBS0238236dstA-/GFP: dstA(237-707): ORF+/[OE]dutAdstA, dutADd-STATa, STATawild type
DBS0252826dstA-/GFP: dstA(237-707): ORF+/[act15]: geneDDB0231646dstA, geneDDB0231646Dd-STATa, STATaaberrant fruiting body morphology
DBS0252825dstA-/GFP: dstA(237-707): ORF+/[act15]: geneDDB0252771dstA, geneDDB0252771Dd-STATa, STATaaberrant fruiting body morphology
DBS0252816dstA-/GFP: dstA(237-707): ORF+/[act15]: hssAdstA, hssADd-STATa, NK20, STATawild type
DBS0252822dstA-/GFP: dstA(237-707): ORF+/[act15]: hssBdstA, hssBDd-STATa, NK20-like, STATawild type
DBS0235931dstB-dstBDd-STATb, STATbdecreased gene expression, decreased growth rate, increased gene expression
DBS0235933dstB-/[act15]: dstBdstBDd-STATb, STATbwild type
DBS0235934dstB-/[act15]: dstB(L1025R)dstBDd-STATb, STATbwild type
DBS0235935dstB-/[act15]: dstB(Y1143F)dstBDd-STATb, STATbwild type
DBS0235932dstB-/dstC-dstB, dstCDd-STATb, Dd-STATc, STATb, STATcwild type
DBS0235936dstC-dstCDd-STATc, STATcmislocalized gene expression, precocious development, precocious gene expression
DBS0235937dtfA-dtfAaberrant cytokinesis, aberrant fruiting body morphology, delayed tip formation
DBS0264941V30466dtfAaberrant cAMP wave formation, wild type
DBS0238234dutA-dutAwild type
DBS0238235[AS]dutAdutAwild type
DBS0235939dwwA-dwwAaberrant F-actin organization, aberrant cell morphology, aberrant cytokinesis
DBS0235940EB1-eb1aberrant mitosis, increased aneuploidy
HJW117ecmA-ecmApDd63long fingers, thin fingers, weak slime trail
HJW01ecmB-ecmB253, SC253, pDd56wild type
HJW03ecmB-ecmB253, SC253, pDd56wild type
DBS0235944ecmF-ecmFwild type
DBS0235946egeB-egeBDG2005, R2005, orfR2005development arrests at mound stage
DBS0237260[inviable]eIF6eIF6inviable
DBS0237537[RNAi]enlAenlAenlazin, fimB, fimbrin-2aberrant cytokinesis, decreased cell-substrate adhesion
DBS0237562[act15]: enlA(92-497)enlAenlazin, fimB, fimbrin-2decreased cell-substrate adhesion
DBS0235444[act6]: myc: eppA(S250A)eppAdecreased growth rate, decreased intracellular cAMP level, delayed development
DBS0235445[act6]: myc: eppA(S325A)eppAdecreased growth rate
DBS0235947eppA-eppAdecreased chemotaxis to cAMP, decreased chemotaxis to folate, decreased growth rate, decreased intracellular cAMP level, delayed development
DBS0235948eppA-/[act6]: myc: eppAeppAwild type
DBS0264183V10223erkAERK1aberrant cAMP wave formation, aberrant streaming
AK240erkB-erkBdagC, erk2abolished aggregation, decreased cAMP-induced cAMP pulse, decreased sporulation
HS174erkB-erkBdagC, erk2abolished aggregation, decreased cAMP-induced cAMP pulse, decreased sporulation
DBS0235949erkB-/regA-erkB, regADG1030, DdPDE2, dagC, erk2, pde2abolished aggregation, increased cAMP-induced cAMP pulse
DBS0265311V30879exoc2sec5aberrant cAMP wave formation, aberrant streaming, wild type
DBS0235951fadA-fadAdes5-1increased resistance to heat shock
DBS0235952fadB-fadBdes5-2wild type
DBS0236034fam45-fam45wild type
DBS0236040fam91-fam91wild type
DBS0235953fbxA-fbxAchtAdecreased sporulation
DBS0235954fbxA-/[ecmA]: GFP(S65T)fbxAchtAincreased prespore cell differentiation
DBS0235956fbxA1-fbxAchtAaberrant fruiting body morphology, delayed culmination, development arrests at slug stage, increased slug migration
DBS0235957fbxA2-fbxAchtAaberrant fruiting body morphology, delayed culmination, development arrests at slug stage, increased slug migration
DBS0235958fbxA3-fbxAchtAaberrant fruiting body morphology, delayed culmination, development arrests at slug stage, increased slug migration
DBS0236358HR42fbxAchtAabolished culmination, decreased sporulation
DBS0237108[act15]: fbxA: FLAGfbxAchtAdecreased prespore cell differentiation
HR46fbxA-/regA-fbxA, regADG1030, DdPDE2, chtA, pde2aberrant fruiting body morphology, decreased sporulation
HR48fbxA-/regA-fbxA, regADG1030, DdPDE2, chtA, pde2aberrant fruiting body morphology, decreased sporulation
DG1148fcpA-fcpADG1148, fcp1aberrant fruiting body morphology
DBS0235960fcsA-fcsALC-FACS 1decreased fatty acid accumulation
DBS0235961fimA-fimAfim, p67, plastindecreased cell size
DBS0237295[RNAi]fimAfimAfim, p67, plastinwild type
DBS0235966forA-forAwild type
DBS0235967forA-/forB-forA, forBwild type
DBS0235968forB-forBwild type
DBS0235969forC-forCaberrant fruiting body morphology, abolished slug migration
DBS0235662[act15]: GFP: forH(1-425)forHdDia2, drf2aberrant protein localization
DBS0235970forH-forHdDia2, drf2decreased cell-substrate adhesion, decreased filopodium formation, increased cell motility
DBS0235971forH-/[act15]: GFP: forHforHdDia2, drf2decreased cell motility, increased cell-substrate adhesion, increased filopodium formation
DBS0237288[unk]skp1fpaA, fpaBFP21, SKP1, fpa1, fpa2aberrant fruiting body morphology
DBS0237109[act15]: fpsfpsDfps, FDPS, FPP, FPPSincreased resistance to bisphosphonates
DBS0264823V30341frmBaberrant culmination, aberrant streaming, wild type
DBS0264377V10642fscDwild type
DBS0235976fszA-fszAFtsZdecreased number of mitochondria, increased number of tubular mitochondria
DBS0235979[act15]: fszA: GFPfszAFtsZincreased number of tubular mitochondria
DBS0235978fszA-/fszB-fszA, fszBFtsZincreased number of tubular mitochondria
DBS0235980fszB-fszBFtsZdecreased growth rate, decreased number of mitochondria, increased number of tubular mitochondria
DG1066fut1-fut1futAaberrant fruiting body morphology
DG1094gacT-gacTDG1094, RacGAPaberrant fruiting body morphology
DBS0264220V10260gacTDG1094, RacGAPaberrant cAMP wave formation, aberrant culmination, aberrant slug migration
DBS0235989gadA-gadAabolished SDF production, decreased sporulation
DBS0235990gbf- (TL198)gbfAGBFabolished gene expression, development arrests at mound stage
DBS0237275[OE]: gbfAgbfAGBFprecocious gene expression
DBS0264204V10244gbfAGBFaberrant culmination, aberrant slug migration
DBS0235994gbpC-gbpCgefTdecreased myosin light chain kinase activation, small fruiting body
DBS0235995gbpC-gbpCgefTaberrant cell morphology, aberrant myosin II organization, decreased cell polarity, decreased chemotaxis rate, small fruiting body
DBS0264337V10537gbpCgefTaberrant cAMP wave formation, aberrant streaming, abolished streaming, wild type
DBS0235996gbpC-/gbpD-gbpC, gbpDRapGEF, gefT, gefUdecreased cell polarity, decreased chemotaxis rate
DBS0235997gbpD-gbpDRapGEF, gefUdecreased cell-substrate adhesion, decreased lateral pseudopod formation, increased cell polarity, increased chemotaxis rate
DBS0235998gbpD-/[act15]: gbpDgbpDRapGEF, gefUaberrant F-actin organization, abolished aggregation, decreased chemotaxis rate, increased cell-substrate adhesion, increased lateral pseudopod formation
DBS0237601[act15]: gbpDgbpDRapGEF, gefUaberrant cell morphology, decreased chemotaxis to cAMP, increased Ras guanyl-nucleotide exchange factor activity, increased cell-substrate adhesion
DBS0237617myoI-/[act15]: gbpDgbpD, myoIDdMVII, M7, MVII, RapGEF, gefUaberrant cell morphology, increased cell-substrate adhesion, increased pseudopod formation
DBS0237615phg2-/[act15]: gbpDgbpD, phg2RapGEF, gefUaberrant cell morphology, abolished chemotaxis to cAMP, increased pseudopod formation
DBS0237622[tet]: rapA(S17N)/[act15]: gbpDgbpD, rapARapGEF, gefU, rap1aberrant cell morphology, increased cell polarity, increased cell-substrate adhesion
DBS0237614rasC-/[act15]: gbpDgbpD, rasCRapGEF, gefUaberrant cell morphology, increased cell-substrate adhesion
DBS0237616talA-/[act15]: gbpDgbpD, talARapGEF, gefUaberrant cell morphology, increased cell-substrate adhesion, increased pseudopod formation
DG1120gbqA-gbqADG1120aberrant fruiting body morphology
DBS0236000gca-/sgcA-gca, sgcAGC, sGCdecreased myosin light chain kinase activation
DBS0236002gcsA-gcsAGCS, gshAabolished gene expression, cell cycle arrest, development arrests at mound stage, inviable, spores inviable
DBS0236003gcsA-/[act15]: gcsAgcsAGCS, gshAdecreased spore viability, development arrests at mound stage
DBS0236004gdt1-gdt1gdtAdecreased growth rate in suspension, increased gene expression, precocious aggregation
DBS0236095gpaB-/gdt1-gdt1, gpaBGa2, Galpha2, gdtA, gpa2abolished aggregation, increased gene expression
DBS0236782pkaC-/gdt1-gdt1, pkaCDdPK2, DdPK3, PK2, PK3, PKA, PKA-C, cAK, gdtA, pkacatabolished aggregation, increased gene expression
DBS0237190gdt1-/[act15]: pkaR(G135E/G261A)gdt1, pkaRPKA, cAK, gdtA, rdeCabolished aggregation, increased gene expression
DBS0236006gdt2-gdt2increased gene expression, precocious aggregation
JB10gefA-gefARasGEF, RasGEFA, aimless, aleAabolished aggregation
RI19gefA-gefARasGEF, RasGEFA, aimless, aleAabolished activation of adenylate cyclase, abolished aggregation, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemoattractant-mediated F-actin polymerization, decreased chemotaxis rate
DBS0252697gefA-gefARasGEF, RasGEFA, aimless, aleAdecreased cell motility
DBS0264205V10245gefARasGEF, RasGEFA, aimless, aleAabolished aggregation, abolished cAMP wave formation, abolished culmination, abolished slug migration, abolished streaming
DBS0236009gefB-gefBRasGEF, RasGEFBaberrant cell morphology, aberrant cytoskeleton organisation, aberrant fruiting body morphology, abolished growth, abolished pinocytosis, decreased aggregate size, decreased growth rate, decreased phagocytosis, delayed aggregation, increased basal F-actin level
DBS0236010gefB-/rasS-gefB, rasSRasGEF, RasGEFBdecreased phagocytosis, increased cell motility
DBS0236868gefC-gefCRasGEF, racGEFwild type
DBS0236869 (DBS0235543)gefD-gefDRacGAP, RasGEF, RasGEFDwild type
DBS0236870gefE-gefERasGEF, RasGEFEaberrant phototaxis, aberrant thermotaxis
DBS0237261[inviable]gefFgefFRasGEF, RasGEFFinviable
DBS0236011gefG-gefGRasGEF, RasGEFGwild type
DBS0236012gefK-gefKRasGEF, RasGEFKwild type
DBS0236871gefL-gefLRasGEF, RasGEFLaberrant phototaxis, aberrant thermotaxis
DBS0264290V10435gefLRasGEF, RasGEFLaberrant cAMP wave formation, aberrant culmination, aberrant slug migration, abolished slug migration
HSB61gefM-gefMRasGEF, RasGEFMaberrant activation of adenylate cyclase activity, decreased cAMP-induced cAMP pulse, decreased chemotaxis rate, decreased lateral pseudopod suppression, development arrests at mound stage, increased cAMP-induced cGMP pulse
DBS0236014gefR-gefRRasGEF, RasGEFRwild type
DBS0264318V10490gefVRasGEF, RasGEFVaberrant cAMP wave formation, aberrant culmination
DBS0237133[act15]: GFP: racH: gemA(630-658)gemA, racHMirodelayed cytokinesis
DBS0264752V30267geneDDB0220123wild type
DBS0264098V10136geneDDB0220630aberrant cAMP wave formation, aberrant culmination, aberrant slug migration, wild type
DBS0265302V30869geneDDB0220712aberrant vegetative growth, wild type
DBS0264335V10535geneDDB0229364aberrant cAMP wave formation, aberrant streaming
DBS0265045V30578geneDDB0229364aberrant cAMP wave formation, aberrant culmination, aberrant slug migration
DBS0265339V30912geneDDB0229877aberrant cAMP wave formation, wild type
DBS0266513geneDDB0230165-/geneDDB0233579-/geneDDB0233577-/geneDDB0233578-/geneDDB0233581-/geneDDB0232259-/geneDDB0238206-geneDDB0230165, geneDDB0232259, geneDDB0233577, geneDDB0233578, geneDDB0233579, geneDDB0233581, geneDDB0238206sigN1wild type
DBS0264905V30427geneDDB0231298aberrant cAMP wave formation, aberrant culmination, aberrant slug migration, aberrant streaming
DBS0266195V31858geneDDB0231435aberrant cAMP wave formation, aberrant streaming, wild type
DBS0266309V31982geneDDB0231435aberrant cAMP wave formation, aberrant streaming, abolished streaming, wild type
DBS0236019geneDDB0231722-geneDDB0231722wild type
DBS0236020geneDDB0231722-geneDDB0231722wild type
DBS0236023geneDDB0231730-geneDDB0231730wild type
DBS0236024geneDDB0231730-geneDDB0231730wild type
DBS0237298[RNAi]geneDDB0231730geneDDB0231730wild type
DBS0236025geneDDB0231732-geneDDB0231732wild type
DBS0237299[RNAi]geneDDB0231732geneDDB0231732wild type