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Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains - Null - Overexpression - Multiple - Other - Developmental

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To view more details, including parent strains and references, click on the corresponding dictyBase ID.

Strain ID Strain Descriptor Associated gene(s) Phenotypes
DBS02354121C7gp130decreased cell-substrate adhesion, delayed development, increased growth rate
DBS023541324EH6racEabolished cytokinesis
DBS02354142F5gp130decreased cell-substrate adhesion, delayed development, increased growth rate
DBS02386015NT-5NTdelayed tip formation, multiple tips in culminant, multiple tips in mound
DBS0235584CF45-1-cf45-1decreased aggregate size, decreased cell motility, increased aggregate size, increased cell-cell adhesion, increased intracellular glucose level
DBS0235585CF50-cf50-1decreased extracellular counting factor component(s) level, increased aggregate size, increased cell-cell adhesion, increased gene expression, increased protein level
DBS0235612CMFR1-cmfBabolished aggregation, decreased gene expression
DBS0235596ChLim-ChLimincreased growth rate, increased phagocytosis
DBS0252637DAip1-DAip1decreased growth rate, decreased phagocytosis, decreased pinocytosis, delayed cytokinesis
DBS0235659DD3-3-DD3-3decreased gene expression, precocious aggregation
DBS0236049DDB_G0268012-DDB_G0268012wild type
DBS0236046DDB_G0268158-DDB_G0268158wild type
DBS0236039DDB_G0268678-DDB_G0268678wild type
DG1007DDB_G0269232-DDB_G0269232abolished culmination
DBS0236025DDB_G0270366-DDB_G0270366wild type
DBS0236026DDB_G0270368-DDB_G0270368wild type
DBS0236036DDB_G0270744-DDB_G0270744wild type
DBS0236043DDB_G0276221-DDB_G0276221wild type
DBS0236042DDB_G0276689-DDB_G0276689wild type
DBS0236041DDB_G0277179-DDB_G0277179wild type
DBS0236045DDB_G0277575-DDB_G0277575wild type
DBS0236044DDB_G0278315-DDB_G0278315wild type
DBS0236038DDB_G0279005-DDB_G0279005wild type
DBS0236032DDB_G0279163-DDB_G0279163wild type
DBS0236033DDB_G0279163-DDB_G0279163wild type
DBS0236028DDB_G0279609-DDB_G0279609wild type
DBS0236029DDB_G0279609-DDB_G0279609wild type
DBS0236035DDB_G0280481-DDB_G0280481wild type
DBS0236019DDB_G0281735-DDB_G0281735wild type
DBS0236020DDB_G0281735-DDB_G0281735wild type
DBS0236027DDB_G0290225-DDB_G0290225wild type
DG1003DDB_G0291992-DDB_G0291992aberrant culminant morphology
DBS0236037DDB_G0292186-DDB_G0292186wild type
DBS0236023DDB_G0293116-DDB_G0293116wild type
DBS0236024DDB_G0293116-DDB_G0293116wild type
DBS0236030DDB_G0293762-DDB_G0293762wild type
DG1039DG1039-DDB_G0284037aberrant fruiting body morphology
DG1040DG1040-DDB_G0276029aberrant fruiting body morphology
DG1041DG1041-DDB_G0269126aberrant fruiting body morphology
DG1054DG1054-DDB_G0277719aberrant fruiting body morphology
DG1060DG1060-DDB_G0281953aberrant fruiting body morphology
DG1062DG1062-DDB_G0286351aberrant fruiting body morphology
DG1074DG1074-DDB_G0272108aberrant fruiting body morphology
DG1080DG1080-DDB_G0281559aberrant fruiting body morphology
DG1091DG1091-DG1091decreased fruiting body size
DG1098DG1098-DG1098decreased fruiting body size
DG1104DG1104-DDB_G0283535abolished aggregation
DG1105DG1105-DG1105abolished aggregation
DG1106DG1106-DG1106abolished aggregation
DG1110DG1110-DDB_G0269128aberrant fruiting body morphology
DG1112DG1112-DG1112decreased stalk width
DG1113DG1113-DG1113increased stalk length
DG1122DG1122-DG1122aberrant fruiting body morphology
DG1124DG1124-DG1124development arrests at loose aggregate stage
DG2033DG2033-DG2033development arrests at mound stage
DG2044DG2044-DG2044development arrests at loose aggregate stage
DBS0266700Dd5P1-Dd5P1wild type
DBS0235660Dd5P2-Dd5P2increased basal F-actin level, wild type
DBS0266702Dd5P3-Dd5P3wild type
DBS0266692Dd5P4-Dd5P4decreased engulfment during phagocytosis, decreased growth rate, decreased phagocytosis, multiple tips in mound
DBS0266693Dd5P4-/ [act15]: Dd5P4Dd5P4wild type
DBS0266719Dd5P4-/ [act15]: Dd5P4: GFPDd5P4wild type
DBS0266695Dd5P4-/ [act15]: GAP5P4Dd5P4decreased growth rate, multiple tips in mound
DBS0266720Dd5P4-/ [act15]: Hs-OCRLDd5P4decreased phagocytosis
DBS0266721Dd5P4-/ [act15]: Hs-OCRL(D422A)Dd5P4decreased phagocytosis
DBS0266694Dd5P4-/ [act15]: cat5P4Dd5P4decreased growth rate, multiple tips in mound
DBS0235940EB1-eb1aberrant mitosis
DBS0236015GEG04K11 (tmcB- in KAX3)tmcBaberrant aggregation during macrocyst formation, increased number of peripheral cells during sexual reproduction, small macrocysts
DBS0236016GEG04V12 (tmcB- in V12)tmcBaberrant aggregation during macrocyst formation, increased number of peripheral cells during sexual reproduction, small macrocysts
DBS0236017GEG10K23 (tmcC- in KAX3)tmcCaberrant aggregation during macrocyst formation, increased number of peripheral cells during sexual reproduction
DBS0236018GEG10V03 (tmcC- in V12)tmcCaberrant aggregation during macrocyst formation, increased number of peripheral cells during sexual reproduction
DBS0302603GFP: disgorgin/ disgorgin-DDB_G0280955wild type
DBS0302615GFP: phgA(1-274: 283-438)/ phgA-phgAaberrant response to hypo-osmotic stress
DBS0302614GFP: phgA/ phgA-phgAwild type
DBS0236085GP138C-cfrCwild type
HTY506HTY506pkaRaberrant fruiting body morphology, aberrant spore morphology, decreased phosphorylation of actin, decreased spore viability, increased sporulation, precocious development
DBS0236716PAKc-pakCdecreased chemotaxis rate, decreased lateral pseudopod suppression
DBS0236779PIPkinA-pik6abolished aggregation, decreased gene expression
DBS0236783PKAcat-pkaCabolished aggregation
DBS0236840R7nosAdevelopment arrests at mound stage
DBS0236900RIP3ripAabolished activation of adenylate cyclase, abolished aggregation, decreased cell polarity, decreased chemotaxis rate, decreased myosin II assembly
DBS0236996TL26cotBaberrant spore coat morphology
DBS0304456[AS]alrA/ gcsA-alrA, gcsAcell cycle arrest, decreased growth rate in suspension
DBS0236827[AS]proA/ proB-proA, proBaberrant cytokinesis, abolished growth, decreased cell motility, development arrests at slug stage, increased basal F-actin level
DBS0238036[AS]proA/ proB-/ [act15]: proAproA, proBwild type
DBS0238037[AS]proA/ proB-/ [act15]: proBproA, proBwild type
DBS0302602[OE]: disgorgin(Delta-Fbox)/ disgorgin-DDB_G0280955wild type
DBS0302601[OE]: disgorgin(Q551A)/ disgorgin-DDB_G0280955aberrant contractile vacuole organization and biogenesis
DBS0302600[OE]: disgorgin(R515A)/ disgorgin-DDB_G0280955aberrant contractile vacuole organization and biogenesis
DBS0302599[OE]: disgorgin/ disgorgin-DDB_G0280955wild type
DBS0302610[OE]: disgorgin/ phgA-DDB_G0280955, phgAaberrant contractile vacuole organization and biogenesis
DBS0302611[OE]: phgA/ disgorgin-DDB_G0280955, phgAaberrant contractile vacuole organization and biogenesis
DBS0302656[act15]: cnrN/ cnrN-cnrNwild type
DBS0302658[act15]: cnrN/ smlA-cnrN, smlAdecreased fruiting body size
DBS0304457[act15]: sodA/ gcsA-gcsA, sodAwild type
DBS0304460[act]: alrA/ gcsA-alrA, gcsAwild type
HAD186aarA-aarAaberrant fruiting body morphology, decreased sporulation
DBS0266687abiA-abiAaberrant cytokinesis, aberrant protein localization, decreased chemotaxis to folate, decreased growth rate, decreased protein level
DBS0266688abiA-abiAaberrant protein localization
DBS0305672abpB-abpBincreased filopodium formation
DBS0236077abpC-abpCaberrant phototaxis, aberrant thermotaxis
DBS0237938abpC-/ [act15]: GFP: abpC(9-148)abpCaberrant phototaxis
DBS0235426abpC-/ [act15]: abpCabpCwild type
DBS0237945abpC-/ [act15]: abpC(1-348: 449-857): GFPabpCaberrant F-actin organization, aberrant phototaxis
DBS0237946abpC-/ [act15]: abpC(1-556: 644-857): GFPabpCaberrant F-actin organization, aberrant phototaxis
DBS0237941abpC-/ [act15]: abpC(1-739): GFPabpCaberrant phototaxis
DBS0237949abpC-/ [cotB]: abpC: GFPabpCaberrant phototaxis
DBS0237948abpC-/ [ecmA]: abpC: GFPabpCwild type
DBS0235427abpD-abpDaberrant development, decreased cell-cell adhesion, decreased spore viability, delayed development
DBS0235428abpE-abpE-1, abpE-2increased lateral pseudopod formation
DBS0235562acaA-acaAabolished aggregation, decreased adenylate cyclase activity
GP6acaA-acaAaberrant F-actin organization, aberrant cell morphology, decreased chemotaxis rate, increased lateral pseudopod formation
TL177acbA-acbAabolished SDF production, abolished sorting to prestalk region, decreased spore viability, increased sensitivity to cisplatin
DBS0235440acgA-acgAprecocious spore germination
DBS0237788acgA-acgAdecreased gene expression, decreased prespore cell differentiation
DBS0237790acgA-/ [acrA]: lacZacgA, acrAmislocalized gene expression
DG1100acrA-acrAdecreased gene expression, decreased sporulation, increased stalk length, spores inviable
DBS0237786acrA-/ [act15]: acgA(1-401)acgA, acrAdecreased gene expression, decreased prespore cell differentiation, decreased sporulation
DBS0238203adrm1-adrm1-1aberrant response to nutrients, precocious development, precocious gene expression
DBS0235457ahhA-ahhAaberrant culminant morphology
DBS0266759alp-alpwild type
DBS0235513alrA-alrAdecreased cell motility, decreased extracellular counting factor component(s) level, decreased intracellular glucose level, increased aggregate size
DBS0235473alrA-/ [act15]: alrAalrAwild type
DBS0235474alxA-alxAaberrant fruiting body morphology, decreased growth rate, development arrests at loose aggregate stage
DBS0235475alxA-alxAaberrant fruiting body morphology, abolished sporulation, decreased gene expression, development arrests at mound stage
DBS0235488alxA-/ [act15]: FLAG: alxAalxAdelayed development
DBS0235476alxA-/ [act15]: alxA(1-596): myc2alxAwild type
DBS0235477alxA-/ [act15]: alxA(1-697): myc2alxAwild type
DBS0235478alxA-/ [act15]: alxA(155-697): myc2alxAaberrant fruiting body morphology
DBS0235479alxA-/ [act15]: alxA(293-697): myc2alxAaberrant fruiting body morphology
DBS0235480alxA-/ [act15]: alxA(460-794): myc2alxAaberrant fruiting body morphology
DBS0235481alxA-/ [act15]: alxA(D310A/ N311A)alxAwild type
DBS0235482alxA-/ [act15]: alxA(Q181E/ Q183)alxAwild type
DBS0235483alxA-/ [act15]: alxA(S700A/ S704A/ S708A)alxAwild type
DBS0235484alxA-/ [act15]: alxA(S700D/ S704D/ S708D)alxAwild type
DBS0235485alxA-/ [act15]: alxA(Y315D)alxAwild type
DBS0235486alxA-/ [act15]: alxA(Y315F)alxAwild type
DBS0235487alxA-/ [act15]: alxA: myc2alxAwild type
DBS0235489alyA-alyAincreased phagocytosis
DG1114amdA-amdAdecreased spore viability, increased prestalk A cell differentiation, translucent sorus
HM1158amdA-amdAdecreased fruiting body size, decreased sporulation, increased aspidocyte differentiation
DBS0235490amiB-amiBabolished aggregation
DBS0235491amiB-amiBabolished aggregation, abolished down-regulation of growth phase genes, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis to cAMP, decreased gene expression
DBS0235493ampA-ampAdecreased prestalk cell differentiation, delayed development, delayed gene expression, delayed tip formation, increased cell-cell adhesion, increased cell-substrate adhesion, mislocalized gene expression, precocious gene expression
BS155amtA-amtAdecreased aggregate size, decreased fruiting body size, decreased slug migration, increased growth rate
DBS0267100amtA-amtAdecreased aggregate size, decreased extracellular ammonia level, decreased spore viability, decreased stalk length, increased intracellular ammonia level, increased intracellular glucose level, increased number of aggregates
DBS0267101amtA-/ [OE]: amtAamtAwild type
BS154amtC-amtCaberrant fruiting body morphology, aberrant protein localization, decreased gene expression, delayed culmination, development arrests at slug stage, mislocalized gene expression
DBS0235501amtC-/ [act15]: cudAamtC, cudAdelayed culmination
DBS0235502amtC-/ [ecmA]: cudAamtC, cudAdelayed culmination
DBS0235503amtC-/ [pspA]: cudAamtC, cudAdevelopment arrests at slug stage
DBS0235505apm1-apm1aberrant contractile vacuole organization and biogenesis, aberrant endosome morphology, aberrant response to hypo-osmotic stress, decreased growth rate, decreased spore germination, decreased stalk width, delayed development
DBS0305085apm2-/ [dscB]: GFP: vamp7Aapm2, vamp7Aincreased localization of protein to the plasma membrane
DBS0235507apm3-apm3aberrant endosome morphology
DBS0305083apm3-/ [dscB]: GFP: vamp7Aapm3, vamp7Aincreased localization of protein to the plasma membrane
DBS0235508apm4-apm4wild type
DBS0235509aprA-aprAaberrant cytokinesis, aberrant fruiting body morphology, decreased spore viability, decreased sporulation, increased aggregate size, increased growth rate
DBS0235510aprA-/ actin15: : aprAaprAaberrant fruiting body morphology, decreased growth rate
DBS0238124aqpA-aqpAdecreased spore viability
DBS0235511arkA-arkAaberrant fruiting body morphology, increased gene expression
DBS0235514aslA-aslA-1, aslA-2wild type
DBS0236305atg1-atg1aberrant macroautophagy, abolished autophagic vacuole formation
DBS0236304atg1-atg1aberrant macroautophagy, abolished autophagic vacuole formation
HR131atg1-atg1aberrant cellular response to nitrogen starvation, abolished aggregation, abolished macroautophagy, abolished sporulation, abolished stalk cell differentiation, decreased growth rate in suspension, decreased growth rate on bacterial plates, increased number of autophagosomes
DBS0238085atg1-/ [act15]: atg1atg1wild type
DBS0238092atg1-/ [act15]: atg1(1-628)atg1aberrant cellular response to nitrogen starvation, abolished aggregation
DBS0238087atg1-/ [act15]: atg1(K36A)atg1aberrant cellular response to nitrogen starvation, abolished aggregation
DBS0238093atg1-/ [act15]: atg1(P138S)atg1abolished aggregation
HR75atg5-atg5aberrant cellular response to nitrogen starvation, aberrant macroautophagy, abolished aggregation, abolished sporulation, multiple tips
HR174 atg6-atg6Aaberrant cellular response to nitrogen starvation, aberrant macroautophagy, decreased fruiting body size, decreased sporulation, decreased stalk length, multiple tips
HR79atg7-atg7aberrant cellular response to nitrogen starvation, aberrant macroautophagy, abolished sporulation, multiple tips
HR141atg8-atg8aberrant cellular response to nitrogen starvation, aberrant macroautophagy, aberrant spore morphology, decreased fruiting body size, decreased sporulation, increased sensitivity to cisplatin, multiple tips
DBS0305977atg9-atg9aberrant fruiting body morphology, aberrant slug formation, aberrant slug migration, aberrant sorus morphology, decreased growth rate, decreased phagocytosis, increased stalk width, multiple tips in mound
TL97cadA-cadAdecreased sporulation, delayed culmination, increased prestalk cell differentiation, multiple tips
DBS0235568car4-carDaberrant fruiting body morphology, decreased gene expression, increased gene expression
DBS0235570carB-carBdevelopment arrests at mound stage
DBS0235573carmil-carmildecreased aggregate size, decreased basal F-actin level, decreased growth rate, decreased pinocytosis
IR40catA-catAabolished catalase activity
IR41catA-catAabolished catalase activity
IR29catA-catAincreased sensitivity to H2O2 (peroxide)
DBS0235574catB-catBdelayed development, spores hypersensitive to H2O2 (peroxide)
DBS0304455cblA-cblA-1, cblA-2aberrant signal transduction, aberrant slug formation, abolished basal disc formation
HC423cbpA-cbpAdecreased cell motility, delayed aggregation, increased aggregate size
DBS0235575cbpJ-cbpJwild type
DBS0235661cdk8-cdk8abolished aggregation, decreased gene expression, mislocalized gene expression
DBS0235578cdk8-/ [cdk8]: cdk8cdk8wild type
DBS0302444cfaD-cfaDaberrant fruiting body morphology, increased growth rate
DBS0302446cfaD-/ [act15]: cfaDcfaDwild type
HO101chcA-chcAaberrant cytokinesis, decreased growth rate, decreased pinocytosis
HO103chcA-chcAaberrant fruiting body morphology, abolished cytokinesis, abolished gene expression, abolished growth in suspension, abolished sporulation, delayed aggregation
DBS0235588chcA-/ [act15]: GFP: mhcAchcA, mhcAdecreased positive regulation of GTPase activity
DBS0302455chcA-/ [act15]: epnA: GFPchcA, epnAaberrant localization of a protein to coated pits
DBS0235589chcA-/ [cotB]: lacZchcAmislocalized gene expression
DBS0235590chcA-/ [ecmA]: lacZchcAmislocalized gene expression
DBS0235591chcA-/ [ecmB]: lacZchcAmislocalized gene expression
DBS0235592chcA-/ [pspA]: lacZchcAmislocalized gene expression
DBS0235601clc-clcaberrant fruiting body morphology, aberrant response to hypo-osmotic stress, abolished cytokinesis, abolished growth
DBS0235604clc-/ [act15]: GFP-clc(146-194)clcaberrant fruiting body morphology, abolished cytokinesis, wild type
DBS0235605clc-/ [act15]: GFP-clc(85-124)clcaberrant fruiting body morphology, abolished cytokinesis, wild type
DBS0235607clc-/ [act15]GFP: clc(1-124)clcaberrant fruiting body morphology, abolished cytokinesis, wild type
DBS0235608clmA-clmAaberrant response to hypo-osmotic stress
DBS0235613cnrB-cnrBwild type
DBS0302655cnrN-cnrNaberrant streaming, increased F-actin polymerization, increased cAMP-induced cAMP pulse, increased number of aggregates
HG1770cnxA-cnxAdecreased extracellular Ca2+ uptake, increased cytosolic Ca2+ response
DBS0235615cofB-cofBwild type
DBS0235616cofC-cofC-1wild type
DBS0235617comB-comBabolished culmination
DG1016comB-comBabolished culmination
DBS0235618comC-comCaberrant aggregation, aberrant streaming
DBS0235619comD-comDabolished culmination
DBS0235620comE-comEaberrant fruiting body morphology, translucent sorus
DBS0235621comF-comF-1, comF-2abolished aggregation
DBS0235622comG-comGdevelopment arrests at mound stage, multiple tips
DBS0235623comH-comHdevelopment arrests at mound stage
HG1570corA-corAaberrant cell morphology, aberrant cytokinesis, decreased cell motility, decreased growth rate
HG1571corA-corAaberrant cell morphology, aberrant cytokinesis, decreased cell motility, decreased growth rate
HG1569corA-corAaberrant cell morphology, aberrant cytokinesis, decreased cell motility, decreased growth rate
DBS0305825corB-corBaberrant phagocytosis, decreased growth rate, increased cell-substrate adhesion, increased lateral pseudopod formation
TL55cotA-cotAaberrant spore coat morphology
TL52cotC-cotCaberrant spore coat morphology
DBS0238297cpnA-cpnAaberrant cytokinesis, aberrant fruiting body morphology, decreased culmination, decreased growth rate, delayed development, delayed response to hypo-osmotic stress
DBS0238320cpnA-/ [act15]: GFP: cpnAcpnAdecreased culmination, delayed development, delayed response to hypo-osmotic stress
DBS0235627crlA-crlAdecreased sorting to prestalk region, delayed tip formation, increased aggregate size, increased growth rate
DBS0235628crlA-/ [crlA]: crlAcrlAincreased aggregate size
DBS0235629crlB-crlBwild type
DBS0235630crlC-crlCwild type
HG1768crtA-crtAdecreased extracellular Ca2+ uptake, increased cytosolic Ca2+ response
DBS0235633crtf-crtfabolished aggregation, abolished sporulation, decreased gene expression
WTC127cshA-cshAdecreased growth rate, decreased phagocytosis, delayed aggregation, development arrests at loose aggregate stage
DBS0235624ctnA-ctnAdecreased basal F-actin level, decreased cAMP-induced cAMP pulse, decreased myosin II assembly, decreased protein level, increased GTP-gamma-S-stimulated guanylyl cyclase activity, increased aggregate size, increased cAMP-induced cGMP pulse, increased cell motility, increased cell-cell adhesion, increased intracellular glucose level, increased protein level
DBS0235636ctnB-ctnBdecreased fruiting body size, decreased gene expression, increased number of aggregates
DG1071ctr9-ctr9aberrant fruiting body morphology
DG1058ctrA-ctrAdecreased fruiting body size
DBS0235598ctxA-ctxAaberrant cell morphology, aberrant cytokinesis
HS1151ctxA-ctxAaberrant cytokinesis, decreased growth rate
DBS0237568ctxA-/ [RNAi]enlActxA, enlAwild type
DBS0237536ctxA-/ [act15]: enlA(92-497)ctxA, enlAwild type
DBS0235600ctxB-ctxBaberrant cell morphology, aberrant cytokinesis
DBS0235639cudA-cudAabolished sporulation, abolished stalk cell differentiation, decreased gene expression, development arrests at slug stage
DBS0235640culA-culAdevelopment arrests at tipped mound stage, multiple tips
DBS0235641culA-/ [cotC]: culAculAdecreased sporulation, decreased stalk length, increased sorus size
DBS0235642culA-/ [ecmA]: culAculAdecreased stalk length, increased sorus size
DBS0235643culA-/ [pkaC]pkaCculA, pkaCwild type
DBS0266745culB-culBaberrant slug formation, decreased fruiting body size, decreased sporulation, multiple tips in mound, precocious gene expression
DBS0266761culB-/ [act15]: pkaCculB, pkaCabolished aggregation, abolished gene expression, abolished sporulation, precocious gene expression
DBS0235651cybA-cybAaberrant development, abolished sporulation
AK108dagA-dagAabolished activation of adenylate cyclase, abolished aggregation, abolished gene expression, decreased gene expression
DBS0235652dagA-/ [act15]: dagAdagAwild type
DBS0235653darA-darAabolished aggregation, decreased aggregate size, decreased cell motility, decreased cell polarity
DBS0236307dcsA-dcsAabolished cellulose biosynthesis
DG1099dcsA-dcsAaberrant spore coat morphology, abolished cellulose biosynthesis, abolished sporulation, abolished stalk cell differentiation, abolished stalk formation
DG1128dcsA-dcsAaberrant spore coat morphology, abolished cellulose biosynthesis, abolished sporulation, abolished stalk formation
TL127dcsA-dcsAaberrant spore coat morphology, abolished cellulose biosynthesis, abolished sporulation, abolished stalk cell differentiation, abolished stalk formation
TL128dcsA-/ [act15]: dcsAdcsAwild type
DBS0235695dgkA-dgkAaberrant development, decreased chemotaxis rate, decreased spore viability, increased myosin II assembly
AK299dhkA-dhkAaberrant fruiting body morphology, aberrant stalk morphogenesis, decreased sporulation, increased gene expression, increased sporulation in the presence of 8-Br-cAMP, mislocalized gene expression
DBS0235704dhkB-dhkBprecocious spore germination
TL135dhkC-dhkCdecreased spore germination, precocious aggregation, precocious culmination, precocious development
DBS0235710dhkK-dhkKaberrant slug migration, delayed culmination, delayed gene expression
DBS0235712dhkK-/ [act15]: dhkK(D1125N)dhkKaberrant fruiting body morphology
DBS0235895dimA-dimAaberrant fruiting body morphology, abolished prestalk cell differentiation, decreased prestalk O cell differentiation, increased prespore cell differentiation, increased slug size, long fingers, thin fingers
DBS0235901dimB-dimBabolished response to DIF
DBS0235903dimB-/ [act15]: dimA: GFPdimA, dimBabolished localization of protein to the nucleus
DBS0235904dimB-/ [act15]: dimB: GFPdimBwild type
DBS0235902dimB-/ [cotB]: lacZdimBincreased prespore cell differentiation
DBS0235906dimB-/ [ecmAO]: lacZdimBdecreased prestalk O cell differentiation
DBS0235907dimB-/ [ecmO]: lacZdimBaberrant prestalk cell differentiation
DBS0302608disgorgin(1-571: 581-733)/ disgorgin-DDB_G0280955aberrant cellular localization, aberrant contractile vacuole organization and biogenesis
DBS0302597disgorgin-DDB_G0280955aberrant contractile vacuole organization and biogenesis, aberrant response to hypo-osmotic stress
DBS0302607disgorgin-/ [OE]: lvsADDB_G0280955, lvsAaberrant contractile vacuole organization and biogenesis
DBS0302606disgorgin-/ [OE]: lvsDDDB_G0280955, lvsDwild type
DBS0302678disgorgin-/ [OE]: rab8ADDB_G0280955, rab8Aaberrant contractile vacuole organization and biogenesis
DBS0302604disgorgin-/ lvsA-DDB_G0280955, lvsAwild type
DBS0302605disgorgin-/ lvsD-DDB_G0280955, lvsDaberrant contractile vacuole organization and biogenesis
DBS0304919dlpA-dlpAaberrant cytokinesis
DBS0304920dlpB-dlpBaberrant cytokinesis
DBS0304921dlpC-dlpCaberrant cytokinesis
DBS0235913dmpA-dmpAaberrant fruiting body morphology, aberrant streaming, decreased sporulation, decreased stalk cell differentiation, delayed development, translucent sorus
HM1030dmtA-dmtAaberrant fruiting body morphology, abolished DIF production, abolished prestalk O cell differentation, decreased lower cup size, decreased outer basal disc size, decreased prestalk O cell differentiation, decreased prestalk cell differentiation, delayed development, delayed tip formation, thin fingers
DBS0235914dnapkcs-dnapkcsincreased sensitivity to DNA-damaging agents
DBS0266875dnapkcs-/ GFP: pcnadnapkcs, pcnaaberrant response to DNA damaging agents
DBS0235915dng1-dng1decreased growth rate, delayed aggregation
DBS0235917dnmA-dnmAdecreased cytosine methylation in genomic DNA
DBS0235916dnmA-dnmAaberrant culminant morphology, decreased cytosine methylation in genomic DNA, decreased sporulation, translucent sorus
DG2015docA-docAdevelopment arrests at mound stage
DBS0235920dokA-dokAaberrant response to hyperosmotic stress, decreased sporulation, translucent sorus
HAD172dpoA-dpoAaberrant development
HAD200dpoA-dpoAaberrant development
HAD201dpoA-dpoAaberrant development
HAD202dpoA-dpoAaberrant development
HAD203dpoA-dpoAaberrant development
DBS0238474drkC-drkCdecreased phagocytosis, decreased phagolysosome formation
DBS0238511drkC-/ [act15]: drkC(1-497): YFPdrkCdecreased phagocytosis
DBS0238513drkC-/ [act15]: drkC(K518R): YFPdrkCdecreased phagocytosis
DBS0238475drkC-/ [act15]: drkC: YFPdrkCwild type
DBS0235924dscA-dscA-1, dscA-2aberrant cell morphology
DBS0235925dstA-dstAaberrant fruiting body morphology, abolished gene expression, abolished sorting to prestalk region, abolished stalk cell differentiation, decreased cell motility, decreased gene expression, delayed aggregation, increased gene expression, mislocalized gene expression
DBS0235926dstA-dstAaberrant fruiting body morphology, abolished sorting to prestalk region, abolished stalk cell differentiation, decreased cell motility, delayed aggregation, mislocalized gene expression
DBS0238237dstA-/ GFP: dstA(237-707): ORF+dstAabolished culmination, decreased stalk length
DBS0238236dstA-/ GFP: dstA(237-707): ORF+/ [OE]dutAdstA, dutAwild type
DBS0252824dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C2C, dstAaberrant fruiting body morphology
DBS0252823dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 7E7E, dstA, hssBwild type
DBS0252826dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165DDB_G0276165, dstAaberrant fruiting body morphology
DBS0252825dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325DDB_G0282325, dstAaberrant fruiting body morphology
DBS0252816dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssAdstA, hssAwild type
DBS0235928dstA-/ [act15]: dstAdstAwild type
DBS0235929dstA-/ [cprB]: dstAdstAwild type
DBS0235930dstA-/ [ecmAO]: dstAdstAwild type
DBS0235931dstB-dstBdecreased gene expression, decreased growth rate, increased gene expression
DBS0235933dstB-/ [act15]: dstBdstBwild type
DBS0235934dstB-/ [act15]: dstB(L1025R)dstBwild type
DBS0235935dstB-/ [act15]: dstB(Y1143F)dstBwild type
DBS0235936dstC-dstCmislocalized gene expression, precocious development, precocious gene expression
DBS0235937dtfA-dtfAaberrant cytokinesis, aberrant fruiting body morphology, delayed tip formation
DBS0238234dutA-dutAwild type
DBS0235939dwwA-dwwAaberrant F-actin organization, aberrant cell morphology, aberrant cytokinesis
HJW117ecmA-ecmAlong fingers, thin fingers, weak slime trail
HJW01ecmB-ecmBwild type
HJW03ecmB-ecmBwild type
DBS0235944ecmF-ecmFwild type
DBS0235946egeB-egeBdevelopment arrests at mound stage
DBS0302590elmoA-elmoAabolished cell polarity, decreased cell motility, decreased culmination, delayed development, increased F-actin polymerization, increased localization of protein to the pseudopodium, increased phagocytosis, increased pseudopod formation
DBS0302591elmoA-/ [act15]: elmoA: GFPelmoAwild type
DBS0302448epnA-epnAaberrant cytokinesis, aberrant protein localization, aberrant spore morphology, abolished protein phosphorylation, decreased spore viability
DBS0302457epnA-/ [act15]: GFP: epnA(253-677)epnAaberrant spore morphology, abolished localization of protein to coated pits, abolished localization of protein to the plasma membrane
DBS0302456epnA-/ [act15]: epnA(1-133): GFPepnAaberrant localization of a protein to coated pits
DBS0302474epnA-/ [act15]: epnA(R65A/ K78A): GFPepnAaberrant spore morphology, abolished localization of protein to coated pits, abolished localization of protein to the plasma membrane, abolished phosphatidylinositol-4, 5-bisphosphate binding
DBS0302475epnA-/ [act15]: epnA(T107A): GFPepnAaberrant spore morphology
DBS0302454epnA-/ [act15]: epnA: GFPepnAwild type
DBS0235947eppA-eppAdecreased chemotaxis to cAMP, decreased chemotaxis to folate, decreased growth rate, decreased intracellular cAMP level, delayed development
DBS0235948eppA-/ [act6]: myc: eppAeppAwild type
HS174erkB-erkBabolished aggregation, decreased cAMP-induced cAMP pulse, decreased cell motility, decreased chemotaxis to cAMP, decreased sporulation
AK240erkB-erkBabolished aggregation, decreased cAMP-induced cAMP pulse, decreased sporulation
DBS0304864expl7-expl7wild type
DBS0235951fadA-fadAincreased resistance to heat shock
DBS0235952fadB-fadBwild type
DBS0236034fam45-fam45wild type
DBS0236040fam91-fam91wild type
DBS0235953fbxA-fbxAdecreased sporulation
DBS0235954fbxA-/ [ecmA]: GFP(S65T)fbxAincreased prespore cell differentiation
DBS0235956fbxA1-fbxAaberrant fruiting body morphology, delayed culmination, development arrests at slug stage, increased slug migration
DBS0235957fbxA2-fbxAaberrant fruiting body morphology, delayed culmination, development arrests at slug stage, increased slug migration
DBS0235958fbxA3-fbxAaberrant fruiting body morphology, delayed culmination, development arrests at slug stage, increased slug migration
DG1148fcpA-fcpAaberrant fruiting body morphology
DBS0235960fcsA-fcsAdecreased fatty acid level
DBS0235961fimA-fimAdecreased cell size
DBS0235966forA-forAwild type
DBS0235968forB-forBwild type
DBS0235969forC-forCaberrant culmination, aberrant fruiting body morphology, development arrests at tipped mound stage
DBS0304905forC-/ [act15]: GFP-forCforCwild type
DBS0235970forH-forHaberrant cell morphology, aberrant pseudopod formation, decreased cell-substrate adhesion, decreased chemotaxis rate, decreased filopodium formation, increased cell motility
DBS0235971forH-/ [act15]: GFP: forHforHdecreased cell motility, increased cell-substrate adhesion, increased filopodium formation
DBS0302506frmA-frmAaberrant cell morphology, decreased aggregate size, decreased cell motility, delayed aggregation, increased cell-substrate adhesion
DBS0304440frmA-/ [unk]: GFPfrmAaberrant development, abolished phototaxis, decreased gene expression, delayed development, increased cell-cell adhesion
DBS0302507frmA-/ [unk]: frmA-HAfrmAwild type
DBS0235976fszA- fszAdecreased number of mitochondria, increased number of tubular mitochondria
DBS0235980fszB- fszBdecreased growth rate, decreased number of mitochondria, increased number of tubular mitochondria
DG1066fut1-fut1aberrant fruiting body morphology
DBS0305025gabT-gabTdecreased sporulation, precocious development
DBS0305026gabT-[pkaC]: pkaCgabT, pkaCaberrant protein secretion
DG1094gacT-gacTaberrant fruiting body morphology
DBS0235989gadA-gadAabolished SDF production, decreased sporulation
TL198gbfA-gbfAabolished gene expression, development arrests at mound stage
DBS0305094gbfA-gbfAabolished autophagic cell death, abolished autophagic vacuole formation
DBS0235994gbpC-gbpCdecreased fruiting body size, decreased myosin light chain kinase activation
DBS0235995gbpC-gbpCaberrant cell morphology, aberrant myosin II organization, decreased cell polarity, decreased chemotaxis rate, decreased fruiting body size
DBS0302680gbpC-gbpCabolished aggregation, decreased aggregate size
DBS0304912gbpC-/ [act15]: gbpCgbpCwild type
DBS0304917gbpC-/ [act15]: gbpC(1-1698: 2005-2631)gbpCdecreased chemotaxis to cAMP
DBS0304918gbpC-/ [act15]: gbpC(311-2631)gbpCdecreased chemotaxis to cAMP
DBS0304916gbpC-/ [act15]: gbpC(F1892A)gbpCdecreased chemotaxis to cAMP
DBS0304915gbpC-/ [act15]: gbpC(F2082A/ E2084A/ F2564A/ E2566A)gbpCdecreased chemotaxis to cAMP
DBS0304913gbpC-/ [act15]: gbpC(K342N)gbpCdecreased chemotaxis to cAMP
DBS0304914gbpC-/ [act15]: gbpC(K905W)gbpCdecreased chemotaxis to cAMP
DBS0235997gbpD-gbpDdecreased cell-substrate adhesion, decreased lateral pseudopod formation, increased cell polarity, increased chemotaxis rate
DBS0235998gbpD-/ [act15]: gbpDgbpDaberrant F-actin organization, abolished aggregation, decreased chemotaxis rate, increased cell-substrate adhesion, increased lateral pseudopod formation
DG1120gbqA-gbqAaberrant fruiting body morphology
DBS0236002gcsA-gcsAabolished gene expression, cell cycle arrest, development arrests at mound stage, inviable, spores inviable
DBS0236003gcsA-/ [act15]: gcsAgcsAdecreased spore viability, development arrests at mound stage
DBS0236004gdt1-gdt1decreased growth rate in suspension, increased gene expression, precocious aggregation
DBS0237190gdt1-/ [act15]: pkaR(G135E/ G261A)gdt1, pkaRabolished aggregation, increased gene expression
DBS0236006gdt2-gdt2increased gene expression, precocious aggregation
RI19gefA-gefAabolished activation of adenylate cyclase, abolished aggregation, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemoattractant-mediated F-actin polymerization, decreased chemotaxis rate
JB10gefA-gefAabolished aggregation
DBS0236009gefB-gefBaberrant cell morphology, aberrant cytoskeleton organisation, aberrant fruiting body morphology, abolished growth, abolished pinocytosis, decreased aggregate size, decreased growth rate, decreased phagocytosis, delayed aggregation, increased basal F-actin level
DBS0236868gefC-gefCwild type
DBS0236869 (DBS0235543)gefD-gefDwild type
DBS0236870gefE-gefEaberrant phototaxis, aberrant thermotaxis
DBS0236011gefG-gefGwild type
DBS0236012gefK-gefKwild type
DBS0236871gefL-gefLaberrant phototaxis, aberrant thermotaxis
HSB61gefM-gefMaberrant activation of adenylate cyclase activity, decreased cAMP-induced cAMP pulse, decreased chemotaxis rate, decreased lateral pseudopod suppression, development arrests at mound stage, increased cAMP-induced cGMP pulse
DBS0304968gefQ-gefQabolished Ras guanyl-nucleotide exchange factor activity, abolished phototaxis, abolished sorting to prestalk region, decreased fruiting body size, increased lateral pseudopod formation, increased myosin II assembly, multiple tips in mound
DBS0304985gefQ-/ [act15]: GFP: gefQ(172-654)gefQabolished Ras guanyl-nucleotide exchange factor activity, decreased phototaxis
DBS0304986gefQ-/ [act15]: GFP: gefQ(910-1298)gefQdecreased phototaxis
DBS0236014gefR-gefRwild type
DG1109ggtA-ggtAaberrant fruiting body morphology
DBS0266723glcS-/ DH1glcSaberrant stalk morphogenesis, decreased fruiting body size, decreased intracellular glycogen level, decreased spore size
DBS0266765glcS-/ HMXglcSaberrant cell morphology, abolished cellulose biosynthesis, decreased autophagic vacuole formation
DBS0236078glpD-glpDaberrant glycogen metabolism
DBS0236079gmsA-gmsAdecreased sexual fusion
DBS0236080gmsA-gmsAdecreased sexual fusion
DBS0238384gnt14-gnt14wild type
DBS0238382gnt15-gnt15abolished aggregation, abolished culmination, decreased gene expression, decreased growth rate, increased calcium-independent cell-cell adhesion
DBS0238383gnt15-gnt15abolished aggregation, abolished culmination, decreased gene expression, decreased growth rate, increased calcium-independent cell-cell adhesion
DBS0238390gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0238391gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0236082gol-golincreased resistance to cisplatin
DBS0236087gpaA-gpaAdecreased stalk width, increased stalk length
JH131gpaA-gpaAwild type
DBS0236091gpaA-/ [ecmB]: lacZgpaAdecreased gene expression
DBS0236092gpaA-/ [gpaA]: gpaA(G45V)gpaAdelayed development
DBS0236093gpaA-/ [gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0236575gpaB-gpaBdecreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse
JH104gpaB-gpaBabolished activation of adenylate cyclase, abolished aggregation, decreased gene expression
DBS0236096gpaB-/ [act15]: gpaBgpaBabolished aggregation
DBS0266942gpaB-/ [act15]: gpaBgpaBdelayed aggregation
DBS0266939gpaB-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB, gpaDabolished aggregation
DBS0237137gpaB-/ [act15]: gpaB(D154V)gpaBaberrant aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate
DBS0237138gpaB-/ [act15]: gpaB(E190G)gpaBaberrant aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse
DBS0237139gpaB-/ [act15]: gpaB(I104S)gpaBaberrant aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate
DBS0237140gpaB-/ [act15]: gpaB(L110S)gpaBaberrant aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate
DBS0237141gpaB-/ [act15]: gpaB(L76P)gpaBabolished aggregation
DBS0237142gpaB-/ [act15]: gpaB(N74D)gpaBabolished aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate
DBS0237143gpaB-/ [act15]: gpaB(R64G)gpaBabolished aggregation, decreased chemotaxis rate
DBS0237144gpaB-/ [act15]: gpaB(S155P)gpaBabolished aggregation, decreased chemotaxis rate
DBS0236097gpaB-/ [gpaA]: gpaBgpaBabolished aggregation
DBS0236099gpaB-/ [gpaB]: gpaBgpaBwild type
DBS0236098gpaB-/ [gpaB]: gpaB(Q208L)gpaBaberrant protein localization
DBS0235986gpaC-gpaCaberrant activation of adenylate cyclase activity, abolished aggregation, decreased gene expression, increased protein kinase A activity
JH417gpaD-gpaDaberrant fruiting body morphology, abolished SDF production, decreased accumulation of cGMP, decreased chemotaxis to folate, decreased gene expression, decreased sporulation
DBS0266944gpaD-/ [act15]: gpaBgpaB, gpaDaberrant fruiting body morphology, decreased accumulation of cGMP, decreased chemotaxis to folate
DBS0266946gpaD-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB, gpaDaberrant fruiting body morphology, decreased accumulation of cGMP
DBS0266943gpaD-/ [act15]: gpaDgpaDwild type
DBS0266945gpaD-/ [act15]: gpaEgpaD, gpaEaberrant fruiting body morphology, decreased accumulation of cGMP, decreased chemotaxis to folate
DBS0266947gpaD-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD, gpaEaberrant fruiting body morphology, decreased accumulation of cGMP, decreased chemotaxis to folate
JH257gpaE-gpaEdelayed gene expression, delayed tip formation
DBS0266941gpaE-/ [act15]: gpaEgpaEprecocious tip formation
DBS0266948gpaE-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD, gpaEprecocious tip formation
LW1gpaG-gpaGaberrant gamma-aminobutyric acid signaling pathway, abolished SDF production, wild type
DBS0236107gpaH-gpaHwild type
DBS0236108gpaH-gpaHwild type
DBS0236109gpaI-gpaIdecreased aggregate size, decreased fruiting body size, increased number of aggregates, precocious aggregation
LW5gpbA-gpbAabolished aggregation
LW6gpbA-gpbAaberrant protein localization, decreased CRAC localization to the plasma membrane, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis to cAMP, decreased chemotaxis to folate, decreased positive regulation of Ras GTPase activity
DBS0304814grlA-grlAabolished SDF production, decreased gene expression, decreased number of spores, delayed culmination, delayed gene expression
DBS0304815grlA-/ [act15]: grlA: GFPgrlAaberrant tip formation
DBS0236112grlE-grlEaberrant gamma-aminobutyric acid signaling pathway, abolished SDF production, decreased sporulation
DBS0236113grlE-grlEaberrant gene expression, decreased chemotaxis to cAMP, delayed aggregation
DBS0238865grlJ-grlJaberrant spore morphology, decreased fruiting body size, decreased spore viability, increased slug size, precocious development, precocious gene expression
DBS0238866grlJ-/ [act15]: grlJ: GFPgrlJwild type
DBS0238686grpA-grpAabolished protein secretion, decreased spore germination
DBS0238687grpA-/ [act15]: grpA-FLAGgrpAwild type
ARK200gskA-gskAdecreased gene expression, decreased sporulation, increased gene expression
DBS0236114gskA-gskAaberrant sorus morphology, decreased slug migration, decreased stalk length
HM338gskA-gskAaberrant fruiting body morphology, decreased prespore cell differentiation, decreased sporulation, increased prestalk cell differentiation, precocious aggregation
DBS0266891gtaC-gtaCaberrant prestalk B cell differentiation, aberrant streaming, abolished stalk cell differentiation in vitro, decreased aggregate size
DBS0236120gxcA-gxcAdecreased chemoattractant-mediated F-actin polymerization, decreased positive regulation of Rac GTPase activity, delayed development
DBS0236121gxcB-gxcBaberrant cytoskeleton organisation, decreased exocytosis, delayed development
DBS0238825gxcDD-gxcDDaberrant streaming, delayed development
DBS0236129hbx2-hbx2wild type
DBS0236130hbx2-hbx2wild type
DBS0236153hcpA-hcpAdecreased growth rate in suspension at low temperature
DBS0236157hcpB-hcpBwild type
DBS0305109hdaB-hdaBdecreased histone deacetylase activity, decreased sporulation
HM1012helC-helCaberrant fruiting body morphology, decreased gene expression, delayed development
HM444helC-helCaberrant fruiting body morphology, decreased gene expression, delayed development
DG1059helE-helEincreased slug migration
DBS0236163helF-helFdelayed development, increased gene silencing by RNA interference, increased slug size, increased stalk cell differentiation
DBS0238583hipA-hipAaberrant spore coat morphology, aberrant spore morphology, decreased spore viability
DBS0252818hssA-hssAwild type
DBS0252699icmA-icmA-1, icmA-2aberrant cAMP wave formation, aberrant fruiting body morphology, aberrant protein localization, aberrant signal transduction during aggregation, abolished cell polarity, abolished growth, abolished sporulation, abolished streaming, delayed gene expression, development arrests at mound stage
DBS0252702icmA-/ [act15]: TAP: YFP: rasGicmA-1, icmA-2, rasGabolished C-terminal protein amino acid methylation
DBS0252701icmA-/ [act15]: hICMTicmA-1, icmA-2wild type
DBS0252700icmA-/ [act15]: icmAicmA-1, icmA-2wild type
DBS0236421icpA-icpAaberrant cytokinesis, aberrant mitosis, aberrant protein localization
DBS0238521icpA-/ [act15]: GFP: icpA(1-1013)icpAaberrant protein localization
BS153ifkA-ifkAdecreased extracellular counting factor component(s) level, increased aggregate size, precocious aggregation, precocious gene expression
BS160ifkB-ifkBincreased gene expression
DBS0236425ino1-ino1abolished growth, decreased intracellular myo-inositol level, decreased phagocytosis, increased intracellular 2, 3-bisphosphoglycerate level, multiple tips in mound
DBS0266326iplA-iplAabolished autophagic cell death, abolished autophagic vacuole formation, abolished cellulose biosynthesis
HM1038iplA-iplAabolished cAMP-induced Ca2+ influx, delayed aggregation, increased chemotaxis to arachidonic acid, precocious aggregation
DBS0252878iptA-iptAdecreased spore viability
DBS0236031kctd9-kctd9wild type
DBS0236489kif12-kif12aberrant cytokinesis, aberrant myosin II organization, aberrant protein localization
DBS0236490kif12-/ [act15]: FLAG: kif12kif12wild type
DBS0302534kif13-kif13decreased spindle stabilization, precocious spindle elongation
DBS0236494kif7-kif7aberrant cell motility
DBS0236491kil1-kil1abolished resistance to pathogenic bacteria
DBS0236492krsA-krsAdecreased chemotaxis to cAMP
DBS0238720krsA-krsAaberrant response to hyperosmotic stress, abolished activation of adenylate cyclase, abolished streaming, decreased aggregate size, decreased cell size, decreased intracellular cAMP level, precocious culmination, precocious gene expression
DBS0236493krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238721krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238722krsA-/ [act15]: GFP: krsA(K49R)krsAaberrant streaming
DBS0238723krsA-/ [act15]: GFP: krsA(T173A)krsAabolished streaming
DBS0238725krsA-/ [act15]: GFP: krsA(deltaC)krsAaberrant streaming
DBS0238724krsA-/ [act15]: GFP: krsA(deltaKinase)krsAabolished streaming
DBS0238726krsA-/ [act15]: GFP: krsA(deltaNS)krsAabolished streaming
DBS0236495ku80-ku80increased sensitivity to DNA-damaging agents
DBS0304820lagB1-tgrB1decreased sporulation, delayed sporulation, development arrests at loose aggregate stage
AK127lagC-tgrC1aberrant aggregation, development arrests at loose aggregate stage, increased aggregate size
DBS0304821lagC1-tgrC1abolished sporulation, development arrests at loose aggregate stage in the presence of EGTA
DBS0236498lagD-tgrD1aberrant aggregation, aberrant cAMP signaling during aggregation, abolished streaming
DBS0236499limB-limBaberrant F-actin organization, aberrant cell-cell adhesion, abolished sorting to prestalk region, decreased cell polarity, decreased cell-substrate adhesion, decreased chemotaxis rate, decreased gene expression, delayed gene expression, development arrests at mound stage
DBS0236502limB-/ [act15]: paxB: GFPlimB, paxBdevelopment arrests at mound stage
DBS0236500limB-/ [cotC]: limBlimBdevelopment arrests at mound stage
DBS0236501limB-/ [ecmAO]: limBlimBwild type
DBS0236503limE-limEaberrant cytokinesis
DBS0236506limF-limFdecreased phagocytosis
DBS0236511lipA-lipAwild type
DBS0236512lipA-lipAwild type
DG1006lipA-lipAabolished culmination
DG1056lipB-captCaberrant fruiting body morphology
DBS0236516lrrA-lrrAaberrant cell morphology, abolished aggregation, abolished chemotaxis, decreased cell polarity, decreased cell-substrate adhesion, decreased gene expression, decreased spore viability, delayed gene expression, development arrests at mound stage, increased aggregate size, increased basal F-actin level
DBS0236517lst8-lst8aberrant activation of adenylate cyclase activity, abolished aggregation, decreased F-actin polymerization, decreased chemotaxis rate, decreased myosin II assembly
AD60lvsA-lvsAaberrant contractile vacuole organization and biogenesis, aberrant response to hypo-osmotic stress, abolished cytokinesis, decreased phagocytosis, decreased pinocytosis, increased cell-substrate adhesion
AD63lvsA-lvsAabolished cAMP-induced Ca2+ influx, abolished cytokinesis
DBS0236521lvsB-lvsBaberrant post-lysosome organization and biogenesis, increased exocytosis, increased lysosome size, increased secretion of lysosomal enzyme
DBS0236522lvsC-lvsCwild type
DBS0236523lvsD-lvsDwild type
DBS0236524lvsE-lvsEwild type
DBS0236525lvsF-lvsFwild type
DBS0236536malA-malAwild type
DBS0236543mekA-mekAdecreased aggregate size, precocious development
DBS0266843mgp1-mgp1aberrant contractile vacuole organization and biogenesis, abolished streaming, decreased cell motility, decreased fruiting body size, decreased stalk length, decreased stalk width, increased filopodium formation, increased phototaxis
DBS0266846mgp1-/ mgp2-mgp1, mgp2aberrant contractile vacuole organization and biogenesis, aberrant culmination, decreased cell motility, decreased phototaxis, decreased stalk length, increased filopodium formation
DBS0266844mgp2-mgp2increased aggregate size, increased slug size
HS1mhcA-mhcAaberrant protein localization
HS2207mhcA-mhcAabolished cytokinesis, development arrests at mound stage
HS2206mhcA-mhcAabolished bleb formation
HK323mhcA-mhcAdecreased cell motility
DBS0266674mhcA-/ [act15]: GFP: abpC(9-148)abpC, mhcAdecreased pseudopod retraction, decreased uropod retraction
DBS0237564mhcA-/ [act15]: GFP: ctxA/ [RNAi]enlActxA, enlA, mhcAaberrant cytokinesis, contractile ring contraction
DBS0266675mhcA-/ [act15]: GFP: mhcA(E476K)mhcAdecreased pseudopod retraction
DBS0236548mhcA-/ [act15]: GFP: pats1(2087-2351)mhcA, pats1aberrant cytokinesis
DBS0236549mhcA-/ [act15]: limE(1-145): GFPlimE, mhcAincreased F-actin polymerization
DBS0238158mhcA-/ [act15]: mhcA(81-2116)mhcAdecreased growth rate, development arrests at tipped mound stage
CW0401mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)mhcAdecreased growth rate in suspension, increased myosin II assembly
DBS0236550mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)mhcAdecreased filopodium formation
DBS0236551mhcA-/ [act15]: mhcA(T1823D/ T1833D/ T2029D)mhcAincreased filopodium formation
DBS0238399mhcA-/ [act15]: rapA(G12V)mhcA, rapAaberrant myosin II organization, increased basal F-actin level, increased cell polarity
DBS0236552mhcA-/ [mhcA]: mhcA(1-1224)mhcAaberrant cytokinesis, development arrests at mound stage
DBS0238157mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R689H)mhcAdecreased actin filament sliding
DBS0236547mhcA-/ [unk]: GFP: icpAicpA, mhcAaberrant protein localization
CW0371mhkA-mhkAincreased myosin II assembly
DBS0236557mhkA-/ [act15]: mhkAmhkAaberrant cytokinesis, decreased growth rate in suspension, decreased myosin II assembly, development arrests at mound stage
CW0166mhkB-mhkBincreased myosin II assembly
CW0403mhkC-mhkCaberrant cytokinesis, increased myosin II assembly
DG1069mhkC-mhkCaberrant fruiting body morphology
CW0435mhkD-mhkDincreased myosin II assembly
DBS0236559midA-midAaberrant spore morphology, decreased cell size, decreased growth rate in suspension, decreased growth rate on bacterial plates, decreased intracellular glycogen level, increased extracellular ammonia level, increased intracellular glutamate level, increased slug migration
DG1020migA-migAaberrant fruiting body morphology, abolished slug migration, decreased fruiting body size
DBS0236560mkcA-mkcAdecreased gene expression
DG1101mkcB-mkcBdecreased fruiting body size
DBS0236564mkkA-mkkAdecreased sorus size, increased stalk length, precocious culmination
DG1121mkpA-mkpAabolished aggregation
DBS0236566mlcE-mlcEaberrant cytokinesis, aberrant development, decreased cell motility, decreased growth rate in suspension, delayed aggregation, mislocalized gene expression
DBS0238058mlcE-/ [act15]: myc: mlcEmlcEwild type
DBS0236567mlcR-mlcRaberrant cytokinesis, aberrant myosin II organization, development arrests at mound stage
HS183mlkA-mlkAaberrant cytokinesis
DG1033modA-modAaberrant fruiting body morphology
DBS0266903mpl1-mpl1abolished aggregation, abolished streaming, decreased cell motility, decreased chemotaxis to cAMP
DBS0266904mpl1-/ [act15]: flag: mpl1mpl1wild type
DBS0236569mrps4-mrps4aberrant fruiting body morphology, delayed aggregation
DBS0236570mybB-mybBabolished aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased gene expression
DBS0236571mybB-mybBabolished aggregation
HM388mybC-mybCabolished culmination, decreased SDF production, decreased gene expression
DBS0236572mybE-mybEabolished outer basal disc formation, increased slug size
DBS0237709mybE-/ [mrrA]: lacZmrrA, mybEaberrant prestalk cell differentiation
DBS0236573mybE-/ mybE: GFPmybEaberrant prestalk cell differentiation, wild type
HDT1myoA-myoAdecreased cell motility, decreased chemotaxis rate, decreased lateral pseudopod suppression, delayed aggregation
HDT2myoA-myoAincreased secretion of lysosomal enzyme
DBS0236579myoB-myoBincreased secretion of lysosomal enzyme
DBS0236580myoB-myoBdecreased cell motility, decreased lateral pseudopod suppression, decreased phagocytosis, delayed aggregation
DBS0236583myoB-/ [AS]myoDmyoB, myoDaberrant aggregation, decreased aggregate size, decreased cell motility, decreased growth rate, decreased phagocytosis, decreased pinocytosis
DBS0236584myoB-/ [AS]myoD/ [KD]myoCmyoB, myoC, myoDaberrant aggregation, decreased aggregate size, decreased cell motility, decreased growth rate, decreased phagocytosis, decreased pinocytosis, increased number of pinosomes, small pinosomes
DBS0236585myoC-myoCdecreased phagocytosis
DBS0236587myoD-myoDwild type
HDT8myoF-myoFwild type
DBS0236589myoI-myoIdecreased spore germination
DBS0236592myoI-myoIaberrant cell morphology, aberrant cytokinesis, decreased cell-substrate adhesion, decreased phagocytosis
HDT15myoI-myoIdecreased phagocytosis
HDT17myoI-myoIdecreased cell-cell adhesion, decreased cell-substrate adhesion, decreased filopodium formation, decreased phagocytosis, decreased protein level
DBS0266889myoI-/ [act15]: GFP: myoImyoIwild type
DBS0266890myoI-/ [act15]: GFP: myoI(809-1154)myoIdecreased phagocytosis
DBS0237617myoI-/ [act15]: gbpDgbpD, myoIaberrant cell morphology, increased cell-substrate adhesion, increased pseudopod formation
HTD7myoJ-myoJwild type
DBS0236595myoM-myoMwild type
SB12napA-napAdecreased basal F-actin level, decreased cell motility, decreased cell polarity, decreased cell size, decreased cell-cell adhesion, decreased cell-substrate adhesion, decreased phototaxis
HC476ncsA-ncsAincreased intracellular cAMP level, precocious development, precocious gene expression
HC477ncsA-ncsAincreased intracellular cAMP level, precocious development, precocious gene expression
DBS0304633nfaA-nfaAaberrant cAMP signaling during aggregation, aberrant localization of protein to the plasma membrane, aberrant regulation of Ras GTPase activity, aberrant regulation of protein kinase activity, decreased cell motility, decreased chemotaxis to cAMP, delayed aggregation, increased basal F-actin level, increased chemoattractant-mediated F-actin polymerization, increased pseudopod formation
DBS0236604nhe1-nhe1aberrant F-actin organization, decreased cell polarity, decreased chemotaxis rate, decreased intracellular pH level
DBS0236605nhe1-/ [act15]: nhe1: HAnhe1wild type
DBS0236606nosA null (15-S-12)nosAdevelopment arrests at mound stage
DBS0236607nosA null (2E4)nosAdevelopment arrests at mound stage
DBS0235950nosA-nosAdevelopment arrests at mound stage
DBS0236608noxA-noxAaberrant development, abolished sporulation
DBS0236611noxA-/ [act15]: noxA: myc2noxAaberrant fruiting body morphology
DBS0236612noxB-noxBaberrant development, abolished sporulation, decreased superoxide production
DBS0236613noxC-noxCaberrant development, abolished sporulation
DBS0238849npcA-npcAwild type
DBS0236695nramp1-nramp1abolished iron ion transport, increased infection rate by Legionella pneumophila, increased infection rate by Mycobacterium avium
DBS0236696nramp1-/ [act15]: nramp1: GFPnramp1decreased infection rate by Legionella pneumophila
DBS0236697nramp1-/ [act15]: nramp1: GFPnramp1decreased infection rate by Legionella pneumophila
DBS0236955nxnA-nxnAdecreased chemotaxis to cAMP, decreased culmination, decreased growth rate, decreased lysosomal enzyme activity, delayed development
DBS0236702nxnA-/ [act15]: GFP: nxnB nxnA, nxnBdevelopment arrests at mound stage
DBS0236704osbA-osbAincreased slug migration, precocious development
DBS0238357p2xA-p2xAaberrant response to hypo-osmotic stress
DBS0238362p2xA-/ [act15]: p2xA: GFPp2xAwild type
DBS0236705pakA-pakAaberrant cytokinesis, delayed development
DBS0236706pakA-pakAwild type
DBS0236707pakA-/ [act15]: pakApakAwild type
DBS0236709pakB-pakBdecreased growth rate
DBS0236710pakB-/ [act15]: GFP-pak(1-337): (563-851)pakBabolished cytokinesis, increased phagocytosis, increased pinocytosis
DBS0236712pakB-/ [act15]: GFP-pak(1-~600)pakBabolished cytokinesis
HC392patB-patBabolished growth in acidic medium, abolished growth on bacterial plates
DBS0236726pats1-pats1aberrant cytokinesis
DBS0236727pats1-/ [act15]: GFP: pats1(2087-2351)pats1aberrant cytokinesis
DBS0236728paxB-paxBaberrant fruiting body morphology, abolished slug migration, decreased cell-substrate adhesion, decreased gene expression, decreased sorting to prestalk region, development arrests at mound stage
DBS0304926paxB-paxBaberrant cell separation during cytokinesis, aberrant cytokinesis, decreased cell motility, decreased cell-substrate adhesion
DBS0304930paxB-/ [act15]: GFP: paxBpaxBwild type
DBS0236730paxB-/ [ecmA]: paxB: GFPpaxBdecreased sorting to prestalk region
DBS0236732paxB-/ [pspA]: paxB: GFPpaxBdecreased sorting to prestalk region
DBS0236733pcp-pcpwild type
DBS0236734pde4-pde4decreased culmination, delayed culmination, delayed slug formation
DBS0236735pde4-/ [act15]: pde4: GFPpde4wild type
DBS0236736pdeD-pdeDdecreased Ca2+-induced Ca2+ influx, decreased cAMP-induced Ca2+ influx, delayed cAMP-induced Ca2+ influx
UK7pdsA-pdsAabolished aggregation, decreased 3', 5'-cyclic-AMP phosphodiesterase activity
DBS0236741pefA-pefAwild type
DBS0236744pefB-pefBwild type
HW260pgtA-pgtAincreased cell size
DBS0236752phdA-phdAdecreased aggregate size, decreased basal F-actin level, decreased chemotaxis rate, decreased fruiting body size
DBS0236753phdA-/ [act15]: phdAphdAwild type
DBS0236754phdA-/ [act15]: phdA: GFPphdAwild type
DBS0304869phg1A-/ [act15]: phg1a(1-276): phg1b(221-587)phg1a, phg1bdecreased phagocytosis
DBS0304868phg1A-/ [act15]: phg1bphg1a, phg1bdecreased cell-substrate adhesion, decreased phagocytosis, increased secretion of lysosomal enzyme
DBS0304870phg1A-/ [act15]: phg1b(1-220): phg1a(277-642)phg1a, phg1bdecreased phagocytosis
DBS0236755phg1a-phg1aaberrant cytokinesis, abolished resistance to pathogenic bacteria, decreased cell-substrate adhesion, decreased growth rate, decreased phagocytosis, development arrests at slug stage, increased secretion of lysosomal enzyme
DBS0236757phg1a-/ [act15]: kil1kil1, phg1awild type
DBS0304866phg1b-phg1babolished culmination, decreased growth rate, decreased phagocytosis, increased secretion of lysosomal enzyme
DBS0236758phg2-phg2aberrant F-actin organization, aberrant cell morphology, aberrant cytokinesis, aberrant response to nutrients, decreased cell motility, decreased cell-substrate adhesion, decreased phagocytosis, precocious development, precocious gene expression
DBS0238400phg2-phg2aberrant cell morphology, decreased chemotaxis to cAMP, increased basal F-actin level, increased cell-substrate adhesion, increased filopodium formation, increased phagocytosis
DBS0236760phg2-/ [act15]: GFP: phg2(199-1389)phg2decreased phagocytosis
DBS0237615phg2-/ [act15]: gbpDgbpD, phg2aberrant cell morphology, abolished chemotaxis to cAMP, increased pseudopod formation
HG1648phgA-phgAaberrant contractile vacuole organization and biogenesis, aberrant response to hypo-osmotic stress
DBS0236761phgA-/ [act6]: GFP: lvsAlvsA, phgAaberrant protein localization
DBS0236762phlp1-phlp1aberrant protein localization, aberrant regulation of protein modification, abolished aggregation, abolished chemotaxis, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased growth rate in suspension, decreased growth rate on bacterial plates
DBS0236763phlp1-/ [OE]: phpl1phlp1wild type
DBS0236764phlp3-phlp3wild type
HW288phyA-phyAabolished culmination, abolished sporulation, abolished stalk formation, decreased peptidyl-proline hydroxylation
DBS0266771phyA-/ [ecmA]: phyA(D132N): mycphyAdecreased peptidyl-proline hydroxylation
DBS0266770phyA-/ [ecmA]: phyA(R276A): mycphyAabolished culmination, abolished peptidyl-proline hydroxylation
DBS0236767pia-piaAaberrant activation of adenylate cyclase activity
DBS0236770piaA-piaAaberrant cytokinesis
DBS0236771piaA-piaAabolished aggregation, decreased myosin II assembly
DBS0304637piaA-piaAaberrant protein tyrosine phosphorylation, decreased cell motility, decreased cell polarity, decreased chemotaxis rate
DBS0236772pikA-pikAwild type
DBS0236774pikB-pikBwild type
DBS0236776pikC-pikCwild type
DBS0236777pikD1pikDaberrant fruiting body morphology, abolished slug migration, decreased aggregate size, decreased number of spores, delayed aggregation
DBS0236778pikE-pikEwild type
SB16pirA-pirAdecreased cell size, increased cell motility
SB3pirA-pirAdecreased cell motility, increased basal F-actin level, increased cell size, increased pseudopod formation
DBS0235411pkaR-pkaRaberrant response to lithium, aberrant response to valproic acid, decreased fruiting body size
DBS0236786pkgB-pkgBabolished SDF production, development arrests at mound stage
DBS0304638pkgB-pkgBdecreased cell-substrate adhesion, decreased chemotaxis rate, increased cell motility
DBS0236787pkgB-/ [act15]: pkbApkbA, pkgBwild type
DBS0236789pkgB-/ [act15]: pkgB(K182M)pkgBdevelopment arrests at mound stage
DBS0236790pkgB-/ [gbfA]: pkbApkbA, pkgBwild type
DBS0236791pkgB-/ [gbfA]: pkgBpkgBwild type
DBS0238068plaA-plaAabolished aggregation
DBS0238067plaA-plaAabolished aggregation
DG1067plbG-plbGdecreased stalk length, decreased stalk width
HAD236plc-plcaberrant chemotaxis to cAMP, abolished aggregation, decreased CRAC localization to the plasma membrane, decreased activation of protein kinase B, decreased localization of protein to the cytoplasm
HD1.19plc-plcaberrant negative chemotaxis
HD10plc-plcwild type
DBS0267125plc-/ [OE]: dagA(PH): GFP/ [OE]: plcdagA, plcaberrant protein localization, decreased chemotaxis to cAMP, increased CRAC localization to the plasma membrane
DBS0236796pldB-pldBprecocious aggregation
DBS0236797pldB-/ [act15]: pldB: GFPpldBabolished aggregation
DBS0236799plip-plipdelayed aggregation
DBS0236820ponA-ponAaberrant development, decreased actin nucleation on plasma membranes, decreased lateral pseudopod traction, precocious aggregation
DBS0236821ponA-ponAaberrant development, decreased actin nucleation on plasma membranes, decreased lateral pseudopod traction, precocious aggregation
DG1057potA-potAaberrant fruiting body morphology
DBS0236824ppk1-ppk1decreased fruiting body size, decreased growth rate on bacterial plates, decreased phagocytosis, decreased sporulation, delayed culmination
DBS0236825ppk1-/ [act15]: ppk1ppk1wild type
DBS0238099ppp4C-ppp4cdelayed development, development arrests at mound stage
DBS0238110ppp4C-/ [act15]: smkAppp4c, smkAdelayed development, development arrests at mound stage
DBS0238033proC-proCdecreased cell polarity, decreased chemotaxis rate, increased lateral pseudopod formation
DBS0238034proC-/ [unk]: FLAG: proCproCwild type
DBS0266716pscA-pscAwild type
HOK2psiA-psiAabolished prespore cell division
DBS0236021psiM-psiMwild type
DBS0236022psiM-psiMwild type
DBS0236828pslA-pslAabolished gene expression, abolished sporulation, abolished stalk cell differentiation in vitro, decreased sorus size, increased aggregate size, increased stalk length, mislocalized gene expression
DBS0236829psmC1-psmC1abolished slug migration, curly fingers, increased cell size, resistant to spectinomycin
DBS0302352psrA-psrAdecreased culmination, delayed development, delayed gene expression, increased protein kinase activation, increased protein phosphorylation
DBS0302356psrA-/ [act15]: FLAG: gskAgskA, psrAincreased protein kinase activation
DBS0302353psrA-/ [act15]: ecmA: lacZpsrAaberrant gene expression
DBS0302354psrA-/ [act15]: ecmB: lacZpsrAaberrant gene expression
DBS0302357psrA-/ [act15]: gskA(K84M/ K85M)gskA, psrAdecreased culmination, decreased gene expression, delayed development
DBS0302355psrA-/ [act15]: psrApsrAwild type
HM1289pten-ptendecreased cell motility
DBS0236830pten-ptenabolished CRAC localization to the plasma membrane, decreased F-actin polymerization, decreased cell motility, decreased chemotaxis to cAMP, decreased lateral pseudopod suppression, increased lateral pseudopod formation
DBS0236832ptpA1-ptpA1-1decreased prespore cell differentiation, increased prestalk O cell differentiation, precocious development
DBS0236833ptpB-ptpBincreased slug size
DBS0236835pufA-pufAaberrant fruiting body morphology, precocious development
DBS0304391pyk3-pyk3decreased gene expression, delayed culmination, increased gene expression, increased prespore cell differentiation
DBS0304393pyk3-/ [act15]: T7: pyk3pyk3wild type
DBS0236837pyr56-pyr56resistant to 5-fluoroorotic acid (5-FOA), uracil auxotroph
DBS0236838pyr56-pyr56resistant to 5-fluoroorotic acid (5-FOA), uracil auxotroph
DBS0236839qkgA-qkgA-1, qkgA-2delayed aggregation, increased aggregate size, increased growth rate
DBS0236841racB-racBaberrant fruiting body morphology, decreased basal F-actin level, decreased chemoattractant-mediated F-actin polymerization, decreased chemotaxis rate, decreased myosin II assembly, delayed aggregation
DBS0236842racC-racCaberrant cell morphology, aberrant protein localization, decreased chemotaxis rate
DBS0237191racC-/ [act15]: CFP: racCracCincreased chemoattractant-mediated F-actin polymerization
DBS0236843racF2-racF2decreased sexual fusion, increased aggregate size, increased cell-cell adhesion
DBS0236849racG-racGdecreased cell motility
DBS0236850racH-racHaberrant protein localization, decreased exocytosis
DBS0266936rapgap1-rapgap1decreased cell motility, decreased myosin II assembly, decreased positive regulation of Rap GTPase activity, increased basal F-actin level, increased cell-substrate adhesion
DBS0266937rapgap1-/ [act15]: GFP: rapgap1rapgap1decreased cell-substrate adhesion, increased basal F-actin level, increased cell motility, increased lateral pseudopod formation, increased myosin II assembly, increased positive regulation of Rap GTPase activity
DBS0236852rasB-rasBdecreased growth rate
DBS0236853rasC-/ AX2rasCabolished aggregation, decreased activation of protein kinase B, decreased cell motility
DBS0236854rasC-/ JH10rasCaberrant gene expression, abolished chemotaxis to cAMP, decreased activation of protein kinase B
DBS0237614rasC-/ [act15]: gbpDgbpD, rasCaberrant cell morphology, increased cell-substrate adhesion
DBS0236860rasD-rasDaberrant phototaxis, aberrant thermotaxis
DBS0236862rasG-/ AX2rasGdecreased activation of protein kinase B, decreased cAMP-induced cGMP pulse, decreased gene expression, delayed aggregation, delayed gene expression
IR15rasG-/ AX2rasGdecreased growth rate, increased cell size
IR17rasG-/ AX3rasGaberrant cytokinesis, decreased cell motility, increased cell size
DBS0236863rasG-/ JH10rasGabolished activation of Rap GTPase activity, decreased activation of protein kinase B, decreased cAMP-induced cGMP pulse, decreased gene expression, delayed aggregation, delayed gene expression
DBS0236864rasG-/ [rasG]: rasBrasB, rasGdecreased growth rate in suspension
DBS0236872rasS-rasSdecreased cell polarity
DBS0236873rasS-rasSaberrant cytoskeleton organisation, abolished growth in suspension, decreased growth rate in liquid medium on solid sufaces, decreased rate of endocytosis, increased basal F-actin level, increased cell motility
DBS0236874rasZ-rasZwild type
DBS0236877rblA-rblAdecreased cell size, increased prestalk cell differentiation in response to DIF-1, increased sorting to prestalk region, precocious development
DBS0236878rbrA-rbrAdecreased gene expression, decreased phototaxis, decreased sorting to prestalk region, decreased sporulation, development arrests at slug stage, increased gene expression, mislocalized gene expression
DBS0236879rbrA-/ [unk]: rbrArbrAwild type
DBS0236880rckA-rckAdelayed gene expression, delayed slug formation, increased aggregate size, increased chemotaxis rate, precocious aggregation
DBS0236885rckA-/ [act15]: myc: rckArckAdecreased chemotaxis rate, delayed development
DBS0236881rckA-/ [act15]: myc: rckA(C551A)rckAdecreased chemotaxis rate, delayed slug formation
DBS0236882rckA-/ [act15]: myc: rckA(E510G)rckAdecreased chemotaxis rate, wild type
DBS0236883rckA-/ [act15]: myc: rckA(E510G/ N511A)rckAdecreased chemotaxis rate, delayed slug formation
DBS0236884rckA-/ [act15]: myc: rckA(K867A)rckAdecreased chemotaxis rate, development arrests at mound stage
FR17rdeA-rdeAaberrant fruiting body morphology, decreased aggregate size, precocious aggregation, precocious development, precocious gene expression
FR17rdeA-rdeAaberrant fruiting body morphology, decreased aggregate size, precocious aggregation, precocious development, precocious gene expression
DBS0236886rdeA-/ [act15]: rdeArdeAwild type
DBS0236887recA-recAincreased sensitivity to H2O2 (peroxide), increased sensitivity to UV light, increased sensitivity to mitomycin C (MMC)
DBS0266664redA-redAaberrant mound color, development arrests at mound stage
DG1047redA-redAaberrant mound color, development arrests at mound stage
DBS0236889regA-regAaberrant fruiting body morphology, increased resistance to cisplatin
HM332regA-regAdecreased lateral pseudopod suppression
HR45regA-regAaberrant fruiting body morphology
DBS0235706regA-/ [act15]: dhkK(D1125N)dhkK, regAaberrant fruiting body morphology, precocious development
DBS0235708regA-/ [act15]: dhkK(H825Q)dhkK, regAaberrant fruiting body morphology, precocious development
DBS0236893rgaA-rgaAaberrant cytokinesis, abolished culmination, abolished sorting to prestalk region, abolished stalk cell differentiation, decreased sporulation
DBS0236894rhgA-rhgAwild type
DBS0236902ripA-/ [unk]: ripA(K680E/ R681E)ripAaberrant development, decreased chemotaxis rate
DBS0236901ripA-/ [unk]ripAripAwild type
DBS0236903rnpA-rnpAincreased gene expression
DBS0238225rpkA-rpkAaberrant response to conditioned medium factor, abolished aggregation, decreased cell motility, decreased cell polarity, development arrests at loose aggregate stage
DBS0236875rtoA-rtoAdecreased infection rate by Legionella pneumophila, decreased rate of endocytosis, delayed culmination, increased prestalk cell differentiation
DBS0236911rtoA-rtoAdelayed development
DBS0236914rzpA-rzpAaberrant aggregation, decreased gene expression, decreased slug migration, delayed development, increased aggregate size, increased gene expression
DBS0236921sadA-sadAaberrant F-actin organization, aberrant cell morphology, aberrant cytokinesis, abolished cell-substrate adhesion, decreased phagocytosis, increased growth rate
DBS0236922sadA-/ [act15]: sadA: GFPsadAwild type
DBS0236924scrA-scrAdecreased basal F-actin level, decreased cell size, decreased fruiting body size, increased lateral pseudopod formation, multiple tips, precocious development
IR46scrA-scrAdecreased cell motility, decreased cell size
IR48scrA-scrAaberrant cytokinesis, decreased growth rate
DBS0236925scrA-scrAincreased filopodium formation
DBS0237774scrA-/ [unk]: scrA(97-443): GFPscrAaberrant cytokinesis, aberrant cytoskeleton organisation, decreased chemotaxis to cAMP, increased cell size
DBS0237779scrA-/ [unk]: scrA: GFPscrAwild type
DBS0236928set1-set1abolished histone H3-K4 methylation, precocious aggregation, precocious gene expression
DG1008sfbA-sfbAdecreased fruiting body size
SA576sgkA- (sgkAΔ)sgkAdecreased growth rate, increased sensitivity to carboplatin, increased sensitivity to cisplatin
HM1091sgkB-sgkBdecreased growth rate, increased sensitivity to carboplatin, increased sensitivity to cisplatin
SA555sglA-sglAaberrant cytoskeleton organisation, abolished slug migration, decreased cell motility, decreased chemotaxis rate, decreased fruiting body size, decreased gene expression, decreased lateral pseudopod suppression, decreased sporulation, increased aggregate size, increased resistance to cisplatin, increased stalk width
SA554sglA-sglAdecreased aggregate size, delayed aggregation
DBS0236934shkA-shkAaberrant F-actin organization, aberrant aggregation, aberrant cytokinesis, decreased cell polarity, decreased chemotaxis rate, decreased fruiting body size, decreased phagocytosis
DBS0236935sibA-sibAdecreased cell-substrate adhesion, decreased phagocytosis
DBS0302653sibC-sibCdecreased phagocytosis
DBS0236936sigB-sigBwild type
DBS0236937sigD-sigDwild type
DBS0236938smkA-smkAaberrant cytokinesis, decreased chemotaxis rate, decreased myosin II assembly, delayed development
HDB7YAsmlA-smlAdecreased GTP-gamma-S-stimulated guanylyl cyclase activity, decreased cAMP-induced cGMP pulse, decreased cell-cell adhesion, decreased fruiting body size, decreased protein level, decreased secretion of lysosomal enzyme, increased basal F-actin level, increased cAMP-induced cAMP pulse, increased cell motility, increased extracellular counting factor component(s) level, increased intracellular counting factor component(s) level, increased myosin II assembly, increased protein level, increased resistance to cisplatin
DBS0304496smlA-/ sslA1(CR11)smlA, sslA1increased fruiting body size
DBS0302523sodC-sodCaberrant cytokinesis
DBS0302524sodC-sodCaberrant aggregation, aberrant cell morphology, aberrant localization of protein to the plasma membrane, decreased chemoattractant-mediated F-actin polymerization, decreased chemotaxis rate, decreased positive regulation of Ras GTPase activity, increased basal F-actin level, increased localization of protein to the plasma membrane
HL351spiA-spiAdecreased spore viability
DBS0236945splA-splAaberrant spore morphology, decreased stalk length, increased sorus size, spores inviable, translucent sorus
DBS0236947spnA-spnAaberrant development, abolished prespore cell differentiation, abolished prestalk cell differentiation, development arrests at mound stage
DBS0236949sr-srdecreased cytochrome C oxidase activity, decreased growth rate, decreased intracellular pteridine level, decreased spore viability
DBS0236950srfA(1-8): lacZsrfAaberrant fruiting body morphology, decreased slug migration, delayed culmination
DBS0236951srfA-srfAaberrant spore coat morphology, aberrant spore morphology, decreased gene expression, decreased spore viability
DBS0266691srfB-srfBaberrant cAMP signaling, aberrant cytokinesis, abolished streaming, decreased growth rate, increased lateral pseudopod formation, increased pinocytosis, precocious aggregation, precocious gene expression
DBS0304409srsA-srsAdecreased gene expression, delayed aggregation, increased aggregate size, increased gene expression
DBS0236952stkA-stkAaberrant fruiting body morphology, decreased gene expression, delayed gene expression, increased gene expression, increased prestalk cell differentiation
HM1157stlA-stlAwild type
HM1154stlB-stlBaberrant fruiting body morphology, abolished DIF production, abolished lower cup formation, abolished outer basal disc formation, abolished prestalk B cell differentation, decreased prestalk O cell differentiation, decreased prestalk cell differentiation
DBS0304547svkA-svkAaberrant cytokinesis, aberrant fruiting body morphology, delayed cell separation during cytokinesis
DBS0236958t96AregAdecreased spore germination, precocious sporulation
AK1200tagA-tagAaberrant fruiting body morphology, abolished SDF production
AK859tagA-tagAabolished SDF production, decreased spore viability, increased prestalk A cell differentiation, multiple tips in mound
AK1201tagA-/ [ecmA]: GFPtagAabolished sorting to prestalk region
AK228tagB-tagBaberrant prestalk A cell differentiation, abolished DIF production, development arrests at mound stage
DBS0236975tagC-tagCdevelopment arrests at mound stage, spores inviable
DBS0236976talA-talAaberrant cell morphology, aberrant cytokinesis, decreased cell-substrate adhesion, decreased phagocytosis
HG1666talA-talAaberrant cytokinesis, decreased cell-cell adhesion, decreased cell-substrate adhesion, decreased growth rate, decreased phagocytosis
HG1663talA-talAdecreased cell-substrate adhesion
HG1664talA-talAdecreased growth rate, decreased phagocytosis
HG1665talA-talAaberrant cytokinesis, decreased cell-cell adhesion
DBS0304585talA-/ [act15]: FLAG: talBtalA, talBdecreased cell-substrate adhesion
DBS0237616talA-/ [act15]: gbpDgbpD, talAaberrant cell morphology, increased cell-substrate adhesion, increased pseudopod formation
DBS0238395talA-/ [act15]: rapA(G12V)rapA, talAincreased cell-substrate adhesion
DBS0304582talA-/ talB-/ [act15]: FLAG: talBtalA, talBwild type
HKT104talB-talBdecreased cell motility, decreased slug migration, development arrests at tipped mound stage, increased protein level
DBS0302472talB-talBabolished autophagic cell death, abolished autophagic vacuole formation
DBS0304586talB-/ [act15]: talA: GFPtalA, talBaberrant fruiting body morphology
AK244tipA-tipAdecreased gene expression, development arrests at mound stage, increased aggregate size, multiple tips
JS56tipB-tipBdevelopment arrests at mound stage, increased aggregate size, multiple tips, multiple tips in mound
JS55tipC-tipCdevelopment arrests at mound stage, increased aggregate size, multiple tips
JS93tipD-tipDdevelopment arrests at mound stage, increased aggregate size, multiple tips
DBS0304519tirA-tirAdecreased growth rate, increased infection rate by Legionella pneumophila
DBS0237017torA-torAdecreased cell motility, decreased chemotaxis rate, decreased growth rate, delayed aggregation
DBS0237018torA-/ [act15]: torA: GFPtorAabolished growth
DBS0237924triA-triAaberrant culminant morphology, aberrant streaming, aberrant upper cup formation, decreased cell fate commitment, decreased cell fate determination, decreased cell-cell adhesion, decreased spore size, decreased spore viability, increased number of aggregates, increased stalk width
DBS0237996triA-triAaberrant culminant morphology
DBS0237997triA-triAaberrant culminant morphology
DBS0237998triA-/ [act15]: GFPtriAaberrant culminant morphology
DBS0237999triA-/ [ecmAO]: lacZ: [ecmAO]: gustriAincreased prestalk O cell differentiation
DBS0238001triA-/ [psA]: lacZ: [psA]: gustriAincreased prespore cell differentiation
DBS0237022tsg101-tsg101decreased fruiting body size
DBS0302370tsuA-tsuAaberrant chemotaxis to cAMP, aberrant chemotaxis to folate, abolished cell polarity, decreased aggregate size, decreased fruiting body size, delayed aggregation, increased period of cAMP wave formation
DBS0302383tsuA-/ [unk]: tsuA(1-1774): YFPtsuAabolished localization of protein to microtubules, abolished localization of protein to the microtubule organizing center, decreased aggregate size, decreased fruiting body size
DBS0302385tsuA-/ [unk]: tsuA(1-260): YFPtsuAabolished localization of protein to microtubules, abolished localization of protein to the microtubule organizing center, decreased aggregate size, decreased fruiting body size
DBS0302384tsuA-/ [unk]: tsuA(1774-2247): YFPtsuAabolished localization of protein to microtubules, abolished localization of protein to the microtubule organizing center, decreased aggregate size, decreased fruiting body size
DBS0302382tsuA-/ [unk]: tsuA(K34R): YFPtsuAdecreased aggregate size, decreased fruiting body size
DBS0302381tsuA-/ [unk]: tsuA: YFPtsuAwild type
DBS0237024ubcB-ubcBdevelopment arrests at mound stage, multiple tips
DBS0237025ubpA-ubpAabolished aggregation, decreased cAMP-induced cAMP pulse, decreased chemotaxis rate, decreased gene expression
DBS0237026ubpB-ubpBaberrant sorus morphology, decreased gene expression, increased gene expression, precocious development
DBS0237027ufc1-ufc1wild type
DBS0266763ugpB-/ DH1ugpBdecreased stalk length
DBS0266764ugpB-/ HMXugpBaberrant cell morphology, abolished cellulose biosynthesis, decreased autophagic vacuole formation
DBS0237031vacA-vacAwild type
DBS0237032vacB-vacBdecreased exocytosis
DBS0237034vasP-vasPabolished filopodium formation
DBS0237035vasP-vasPaberrant F-actin organization, abolished filopodium formation, decreased cell size, decreased cell-substrate adhesion, decreased chemotaxis rate, decreased filopodium formation, decreased lateral pseudopod suppression
DBS0237033vasP-/ [act15]: GFP: vasP(1-264/ 285-380)vasPabolished filopodium formation
DBS0237836vasP-/ [act15]: YFP: wipAvasP, wipAdecreased filopodium formation
DBS0237842vasP-/ [act15]: YFP: wipA/ [act15]: vasP: FLAGvasP, wipAincreased filopodium formation
DBS0237036vasP-/ [act15]: myr: vasPvasPaberrant cytokinesis, increased basal F-actin level, increased filopodium formation
DBS0237040vasP-/ [act15]: vasPvasPdecreased filopodium formation
DBS0237840vasP-/ [act15]: vasPvasPincreased basal F-actin level, increased filopodium formation
DBS0237037vasP-/ [act15]: vasP(1-110: 231-380)vasPaberrant cytokinesis, decreased filopodium formation, increased basal F-actin level
DBS0237038vasP-/ [act15]: vasP(1-228)vasPdecreased filopodium formation
DBS0237039vasP-/ [act15]: vasP(111-380)vasPincreased basal F-actin level, increased filopodium formation
DBS0304927vinA-vinAwild type
DBS0236058vmp1-vmp1aberrant aggregation, aberrant response to hypo-osmotic stress, decreased exocytosis, decreased gene expression, decreased growth rate, decreased pinocytosis
DG1118vps46-vps46increased sorus size
DBS0237046vwkA-vwkAaberrant cytokinesis, aberrant fruiting body morphology, decreased growth rate in suspension, delayed development, increased myosin II assembly, increased protein level
TL61wacA-wacAwild type
TL99wacA-wacAwild type
DBS0237048warA-warAdecreased prespore cell differentiation, development arrests at slug stage, increased basal disc size, increased prestalk O cell differentiation
DBS0237049warA-warAdecreased prespore cell differentiation, development arrests at slug stage, increased basal disc size, increased prestalk O cell differentiation
DG1053wimA-wimAaberrant fruiting body morphology
DG1064wimA-wimAaberrant fruiting body morphology
AK235yakA-yakAabolished aggregation
AK800yakA-yakAabolished aggregation
DBS0237091yakA-/ [crlA]: crlAcrlA, yakAabolished growth
DG1014yelA-yelAaberrant mound color, decreased spore viability, development arrests at mound stage, precocious sporulation
ARK100-110zakA-zakAaberrant fruiting body morphology, decreased gene expression, decreased glycogen synthase kinase 3 activity, decreased sporulation, delayed culmination, increased gene expression
DBS0238142zakA-zakAdevelopment arrests at tipped mound stage
DG1050zipA-zipAdecreased fruiting body size

Last updated February 28, 2010

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