Phenotypes for Dictyostelium mutants
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To view more details, including parent strains and references, click on the corresponding dictyBase ID.
| Strain ID |
Strain Descriptor |
Associated gene(s) |
Strain Name(s) |
Phenotypes |
| DBS0237786 | acrA-/[act15]: acgA(1-401) | acgA, acrA | ACB, ACG, ACR, DG1100 | decreased gene expression, decreased prespore cell differentiation, decreased sporulation |
| DBS0238088 | [act15]: atg1(K36A) | atg1 | APG1 | aberrant cellular response to nitrogen starvation, abolished aggregation, abolished macroautophagy, increased number of autophagosomes |
| DBS0238093 | atg1-/[act15]: atg1(P138S) | atg1 | APG1 | abolished aggregation |
| DBS0237273 | [AS]calA | calA | | abolished cytokinesis |
| DBS0252740 | [act15]: carA(I104D) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | aberrant cAMP wave formation, decreased MAP kinase activation, delayed aggregation, increased cAMP binding |
| DBS0252744 | [act15]: carA(I104E) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | aberrant cAMP wave formation, delayed aggregation, increased cAMP binding |
| DBS0252745 | [act15]: carA(I104Q) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0252746 | [act15]: carA(I104N) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0252747 | [act15]: carA(I104H) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0252748 | [act15]: carA(I104Y) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | aberrant cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0252749 | [act15]: carA(I104K) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished aggregation, abolished cAMP wave formation, decreased MAP kinase activation, increased cAMP binding |
| DBS0252750 | [act15]: carA(I104R) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0235570 | carB- | carB | cAR2 | development arrests at mound stage |
| DBS0237098 | [act15]: cdk5(D144N) | cdk5 | crp, crpA | decreased extracellular counting factor component(s) level, decreased growth rate, decreased phagocytosis, decreased pinocytosis, decreased sporulation, delayed aggregation, increased aggregate size, increased extracellular counting factor component(s) level, increased intracellular counting factor component(s) level |
| DBS0238351 | [tet]: [RNAi]cinC | cinC | EF2, Ef-2b, H6 | decreased growth rate, decreased translation, precocious aggregation |
| DBS0237224 | [AS]cmfA | cmfA | CMF | abolished aggregation |
| DBS0235409 | [RNAi]cnbA | cnbA | CNB | aberrant stalk cell differentiation, decreased gene expression, decreased stalk length, multiple tips in culminant |
| DBS0237568 | ctxA-/[RNAi]enlA | ctxA, enlA | enlazin, fimB, fimbrin-2 | wild type |
| DBS0237564 | mhcA-/[act15]: GFP: ctxA/[RNAi]enlA | ctxA, enlA, mhcA | MHC, enlazin, fimB, fimbrin-2 | aberrant cytokinesis, contractile ring contraction |
| DBS0237225 | [AS]cupB | cupB | | abolished aggregation |
| DBS0266721 | Dd5P4-/[act15]: Hs-OCRL(D422A) | Dd5P4 | PI5P4, RacGAP | decreased phagocytosis |
| DBS0237226 | [AS]dia1 | dia1 | DIA-1 | decreased gene expression, precocious aggregation |
| dia2AS | AX2/[act15]: [AS]dia2 | dia2 | | development arrests at mound stage |
| DBS0238235 | [AS]dutA | dutA | | wild type |
| DBS0237295 | [RNAi]fimA | fimA | fim, p67, plastin | wild type |
| DBS0237622 | [tet]: rapA(S17N)/[act15]: gbpD | gbpD, rapA | RapGEF, gefU, rap1 | aberrant cell morphology, increased cell polarity, increased cell-substrate adhesion |
| DBS0237190 | gdt1-/[act15]: pkaR(G135E/G261A) | gdt1, pkaR | PKA, cAK, gdtA, rdeC | abolished aggregation, increased gene expression |
| DBS0237228 | [AS]GP138A/[AS]GP138B | GP138A, GP138B | fusA, fusB | decreased sexual fusion |
| DBS0236092 | gpaA-/[gpaA]: gpaA(G45V) | gpaA | Ga1, Galpha1, gpa1 | delayed development |
| DBS0236093 | gpaA-/[gpaA]: gpaA(Q206L) | gpaA | Ga1, Galpha1, gpa1 | increased basal disc size |
| DBS0237229 | [AS]gpaA | gpaA | Ga1, Galpha1, gpa1 | wild type |
| DBS0237252 | [gpaA]: gpaA(G45V) | gpaA | Ga1, Galpha1, gpa1 | delayed development |
| DBS0237253 | [gpaA]: gpaA(Q206L) | gpaA | Ga1, Galpha1, gpa1 | increased basal disc size |
| HPF414 | [AS]hspA | hspA | | aberrant phototaxis, decreased growth rate |
| DBS0238749 | [AS]hspA/snfA | hspA, snfA | AMPK?, SNF1, pkraa | wild type |
| DBS0252819 | [AS]hssA | hssA | NK20 | wild type |
| DBS0252820 | [RNAi]hssA | hssA | NK20 | wild type |
| DBS0237230 | [AS]ino1 | ino1 | ISYNA1, MIPS | abolished growth |
| DBS0237310 | [RNAi]lipA | lipA | ALOX, DG1006 | wild type |
| DBS0238399 | mhcA-/[act15]: rapA(G12V) | mhcA, rapA | MHC, rap1 | aberrant myosin II organization, increased basal F-actin level, increased cell polarity |
| DBS0236904 | [AS]rps4 | mrps4 | dia3, rps4 | aberrant fruiting body morphology, delayed aggregation |
| DBS0236584 | myoB-/[AS]myoD/[KD]myoC | myoB, myoC, myoD | DMIB, DMIC, DMID, abmB, abmC, myoIB, myoIC, myoID | aberrant aggregation, decreased aggregate size, decreased cell motility, decreased growth rate, decreased phagocytosis, decreased pinocytosis, increased number of pinosomes, small pinosomes |
| DBS0236583 | myoB-/[AS]myoD | myoB, myoD | DMIB, DMID, abmB, myoIB, myoID | aberrant aggregation, decreased aggregate size, decreased cell motility, decreased growth rate, decreased phagocytosis, decreased pinocytosis |
| HM1060 | nsfA(A1847G, A1939T, T1977C, T2005G, A2025T, A2366T) | nsfA | nsf | abolished cell motility, decreased F-actin polymerization at the leading edge, decreased phagocytosis, decreased rate of endocytosis |
| HM1067 | nsfA(A1854T, T1984A, C2131A, A2398T, T2574A) | nsfA | nsf | abolished cell motility, decreased F-actin polymerization at the leading edge, decreased cell motility, decreased rate of endocytosis, increased phagocytosis |
| DBS0237183 | [act15]: pakA(K394A) | pakA | DPAKa, dpak1 | delayed development, development arrests at mound stage |
| DBS0237184 | [act15]: pakA[CA] | pakA | DPAKa, dpak1 | abolished aggregation |
| DBS0236725 | [AS]patA | patA | PAT1 | decreased growth rate under Ca2+ stress |
| DBS0237504 | [AS]pikE | pikE | DdPIK5, PIK5, VPS34 | aberrant stalk morphogenesis, decreased growth rate |
| DBS0236789 | pkgB-/[act15]: pkgB(K182M) | pkgB | DK2, PK2, PKBR1, pkfA | development arrests at mound stage |
| DBS0237296 | [RNAi]pks16 | pks16 | FAS, dipks16 | wild type |
| DBS0238108 | [act15]: FLAG: pppC(H113Q) | ppp4C | PP4C, pppC | delayed development, development arrests at mound stage |
| DBS0237232 | [AS]proA | proA | | wild type |
| DBS0236827 | [AS]proA/proB- | proA, proB | | aberrant cytokinesis, abolished growth, decreased cell motility, development arrests at slug stage, increased basal F-actin level |
| DBS0238036 | [AS]proA/proB-/[act15]: proA | proA, proB | | wild type |
| DBS0238037 | [AS]proA/proB-/[act15]: proB | proA, proB | | wild type |
| DBS0237318 | [tet]: pten | pteN | ptenA | decreased cell motility |
| DBS0237311 | [RNAi]racF2 | racF2 | | abolished growth in suspension |
| DBS0237132 | [act15]: GFP: racH(T18N) | racH | | aberrant cell morphology, aberrant cytokinesis |
| DBS0236851 | [AS]rapA | rapA | rap1 | aberrant osmosensory signaling pathway, aberrant response to hyperosmotic stress, decreased phagocytosis, decreased pinocytosis, increased basal phosphorylated actin level, inviable |
| DBS0238393 | [act15]: GFP: rapA(G12V) | rapA | rap1 | increased cell-substrate adhesion |
| DBS0238394 | [act15]: GFP: rapA(S17N) | rapA | rap1 | decreased cell-substrate adhesion |
| DBS0238396 | [act15]: myc: rapA(G12V) | rapA | rap1 | decreased cell motility, delayed aggregation, increased cell-substrate adhesion |
| DBS0238397 | [act15]: myc: rapA(S17N) | rapA | rap1 | decreased cell-substrate adhesion |
| DBS0238395 | talA-/[act15]: rapA(G12V) | rapA, talA | rap1 | increased cell-substrate adhesion |
| DBS0236884 | rckA-/[act15]: myc: rckA(K867A) | rckA | rck1 | decreased chemotaxis rate, development arrests at mound stage |
| DBS0238734 | [RNAi]sdhA | sdhA | | abolished aggregation, decreased phototaxis |
| HM1163 | sec1(M213K, E258G, M427V, K527I, T541N, F558S, N581D) | sec1 | Stxbp1, sec1A | abolished cell motility |
| DBS0238748 | [AS]snfA | snfA | AMPK?, SNF1, pkraa | aberrant mitochondrion organization and biogenesis, decreased intracellular ATP level, decreased number of mitochondria, increased growth rate, small fruiting body |
| DBS0237235 | [AS]tcp1 | tcp1 | DdTcp-1, TCP-1, cct1, tcp | aberrant fruiting body morphology, decreased growth rate, development arrests at mound stage |
| DBS0237236 | [AS]: [tet]: trrA | trrA | trr | abolished aggregation, decreased growth rate, delayed development |
| DBS0237051 | wasA1- | wasA | WASP | aberrant F-actin organization, decreased cell motility, delayed development |
| DBS0237052 | wasA1-/[tet]: YFP: wasA2 | wasA | WASP | aberrant F-actin organization, abolished aggregation, abolished chemotaxis, decreased F-actin polymerization |
| DBS0237811 | wasA1-/[tet]: YFP: wasA2/[act15]: wasA(Y33A/W39A/F90A/F91A) | wasA | WASP | decreased F-actin polymerization, decreased F-actin polymerization at the leading edge |
| DBS0237820 | wasA1-/[tet]: YFP: wasA2/[act15]: wipA | wasA, wipA | WASP, WIPa | abolished chemotaxis |
| DBS0237818 | [RNAi]wipA | wipA | WIPa | decreased F-actin polymerization at the leading edge, decreased chemotaxis to cAMP, decreased filopodium formation, delayed pseudopod formation |
Last updated May 30, 2008
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