Phenotypes for Dictyostelium mutants
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| Strain ID |
Strain Descriptor |
Associated gene(s) |
Strain Name(s) |
Phenotypes |
| DBS0252824 | dstA-/GFP: dstA(237-707): ORF+/[act15]: 2C | 2C, dstA | Dd-STATa, STATa | aberrant fruiting body morphology |
| DBS0252823 | dstA-/GFP: dstA(237-707): ORF+/[act15]: 7E | 7E, dstA, hssB | Dd-STATa, NK20-like, STATa | wild type |
| DBS0235426 | abpC-/[act15]: abpC | abpC | ABP-120, ABP120, FLN, ddFLN, gelA | wild type |
| DBS0237938 | abpC-/[act15]: GFP: abpC(9-148) | abpC | ABP-120, ABP120, FLN, ddFLN, gelA | aberrant phototaxis |
| DBS0237941 | abpC-/[act15]: abpC(1-739): GFP | abpC | ABP-120, ABP120, FLN, ddFLN, gelA | aberrant phototaxis |
| DBS0237945 | abpC-/[act15]: abpC(1-348: 449-857): GFP | abpC | ABP-120, ABP120, FLN, ddFLN, gelA | aberrant F-actin organization, aberrant phototaxis |
| DBS0237946 | abpC-/[act15]: abpC(1-556: 644-857): GFP | abpC | ABP-120, ABP120, FLN, ddFLN, gelA | aberrant F-actin organization, aberrant phototaxis |
| DBS0237096 | [act15]: abpE | abpE | Dabp1 | aberrant aggregation, decreased cell motility, delayed development, increased lateral pseudopod formation, small fruiting body |
| DBS0237114 | [act15]: GFP: abpE(413-481) | abpE | Dabp1 | increased lateral pseudopod formation |
| DBS0237786 | acrA-/[act15]: acgA(1-401) | acgA, acrA | ACB, ACG, ACR, DG1100 | decreased gene expression, decreased prespore cell differentiation, decreased sporulation |
| DBS0235473 | alrA-/[act15]: alrA | alrA | | wild type |
| DBS0235476 | alxA-/[act15]: alxA(1-596): myc2 | alxA | ALIX, DdAlix, alx | wild type |
| DBS0235477 | alxA-/[act15]: alxA(1-697): myc2 | alxA | ALIX, DdAlix, alx | wild type |
| DBS0235478 | alxA-/[act15]: alxA(155-697): myc2 | alxA | ALIX, DdAlix, alx | aberrant fruiting body morphology |
| DBS0235479 | alxA-/[act15]: alxA(293-697): myc2 | alxA | ALIX, DdAlix, alx | aberrant fruiting body morphology |
| DBS0235480 | alxA-/[act15]: alxA(460-794): myc2 | alxA | ALIX, DdAlix, alx | aberrant fruiting body morphology |
| DBS0235481 | alxA-/[act15]: alxA(D310A/N311A) | alxA | ALIX, DdAlix, alx | wild type |
| DBS0235482 | alxA-/[act15]: alxA(Q181E/Q183) | alxA | ALIX, DdAlix, alx | wild type |
| DBS0235483 | alxA-/[act15]: alxA(S700A/S704A/S708A) | alxA | ALIX, DdAlix, alx | wild type |
| DBS0235484 | alxA-/[act15]: alxA(S700D/S704D/S708D) | alxA | ALIX, DdAlix, alx | wild type |
| DBS0235485 | alxA-/[act15]: alxA(Y315D) | alxA | ALIX, DdAlix, alx | wild type |
| DBS0235486 | alxA-/[act15]: alxA(Y315F) | alxA | ALIX, DdAlix, alx | wild type |
| DBS0235487 | alxA-/[act15]: alxA: myc2 | alxA | ALIX, DdAlix, alx | wild type |
| DBS0235488 | alxA-/[act15]: FLAG: alxA | alxA | ALIX, DdAlix, alx | delayed development |
| DBS0235501 | amtC-/[act15]: cudA | amtC, cudA | | delayed culmination |
| DBS0235502 | amtC-/[ecmA]: cudA | amtC, cudA | | delayed culmination |
| DBS0235503 | amtC-/[pspA]: cudA | amtC, cudA | | development arrests at slug stage |
| DBS0238085 | atg1-/[act15]: atg1 | atg1 | APG1 | wild type |
| DBS0238086 | [act15]: atg1 | atg1 | APG1 | wild type |
| DBS0238087 | atg1-/[act15]: atg1(K36A) | atg1 | APG1 | aberrant cellular response to nitrogen starvation, abolished aggregation |
| DBS0238088 | [act15]: atg1(K36A) | atg1 | APG1 | aberrant cellular response to nitrogen starvation, abolished aggregation, abolished macroautophagy, increased number of autophagosomes |
| DBS0238089 | atg1-/[act15]: atg1(K36A/1-628) | atg1 | APG1 | aberrant cellular response to nitrogen starvation, abolished aggregation |
| DBS0238090 | [act15]: atg1(K36A/1-628) | atg1 | APG1 | wild type |
| DBS0238091 | [act15]: atg1(1-628) | atg1 | APG1 | wild type |
| DBS0238092 | atg1-/[act15]: atg1(1-628) | atg1 | APG1 | aberrant cellular response to nitrogen starvation, abolished aggregation |
| DBS0252732 | [act15]: carA(I104C) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | decreased MAP kinase activation |
| DBS0252733 | [act15]: carA(I104W) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | increased cAMP binding |
| DBS0252734 | [act15]: carA(I104P) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | decreased MAP kinase activation |
| DBS0252735 | [act15]: carA(I104T) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | aberrant cAMP wave formation, increased cAMP binding |
| DBS0252737 | [act15]: carA(I104A) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | decreased cAMP binding |
| DBS0252738 | [act15]: carA(I104G) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | decreased MAP kinase activation, increased cAMP binding |
| DBS0252740 | [act15]: carA(I104D) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | aberrant cAMP wave formation, decreased MAP kinase activation, delayed aggregation, increased cAMP binding |
| DBS0252741 | [act15]: carA(I104F) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | decreased MAP kinase activation, increased cAMP binding |
| DBS0252742 | [act15]: carA(I104M) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | increased cAMP binding |
| DBS0252743 | [act15]: carA(I104S) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | aberrant cAMP wave formation, decreased MAP kinase activation, increased cAMP binding |
| DBS0252744 | [act15]: carA(I104E) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | aberrant cAMP wave formation, delayed aggregation, increased cAMP binding |
| DBS0252745 | [act15]: carA(I104Q) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0252746 | [act15]: carA(I104N) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0252747 | [act15]: carA(I104H) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0252748 | [act15]: carA(I104Y) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | aberrant cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0252749 | [act15]: carA(I104K) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished aggregation, abolished cAMP wave formation, decreased MAP kinase activation, increased cAMP binding |
| DBS0252750 | [act15]: carA(I104R) | carA-1, carA-2 | cAR1, carA, carA1, carA2 | abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding |
| DBS0266697 | rasC-/rasG-/[act15]: carA | carA-1, carA-2, rasC, rasG | cAR1, carA, carA1, carA2, ddRASG | abolished activation of Rap GTPase activity, abolished cAMP-induced cGMP pulse, abolished chemotaxis to cAMP, abolished growth, abolished protein kinase B activation, decreased activation of adenylate cyclase, decreased growth rate |
| DBS0237162 | [act15]: myc-cdk8 | cdk8 | CDK, Ddcdk8 | multiple tips |
| DBS0237274 | [OE]: chlim | ChLim | | decreased growth rate, decreased phagocytosis, increased basal F-actin level |
| DBS0235604 | clc-/[act15]: GFP-clc(146-194) | clc | clcA | aberrant fruiting body morphology, abolished cytokinesis, wild type |
| DBS0235605 | clc-/[act15]: GFP-clc(85-124) | clc | clcA | aberrant fruiting body morphology, abolished cytokinesis, wild type |
| DBS0235607 | clc-/[act15]GFP: clc(1-124) | clc | clcA | aberrant fruiting body morphology, abolished cytokinesis, wild type |
| DBS0237102 | [act15]: cofA | cofA | DCOF1 | increased actin bundle formation, increased cell motility, increased membrane ruffling |
| DBS0238320 | cpnA-/[act15]: GFP: cpnA | cpnA | | decreased culmination, delayed development, delayed response to hypo-osmotic stress |
| DBS0237091 | yakA-/[crlA]: crlA | crlA, yakA | dagB | abolished growth |
| DBS0237104 | [act15]: dagA | dagA | CRAC, synag7 | wild type |
| DBS0266694 | Dd5P4-/[act15]: cat5P4 | Dd5P4 | PI5P4, RacGAP | decreased growth rate, multiple tips in mound |
| DBS0266695 | Dd5P4-/[act15]: GAP5P4 | Dd5P4 | PI5P4, RacGAP | decreased growth rate, multiple tips in mound |
| DBS0266719 | Dd5P4-/[act15]: Dd5P4: GFP | Dd5P4 | PI5P4, RacGAP | wild type |
| DBS0266720 | Dd5P4-/[act15]: Hs-OCRL | Dd5P4 | PI5P4, RacGAP | decreased phagocytosis |
| DBS0266721 | Dd5P4-/[act15]: Hs-OCRL(D422A) | Dd5P4 | PI5P4, RacGAP | decreased phagocytosis |
| DBS0237106 | [act15]: dhkC(394-661) | dhkC | | increased slug migration |
| DBS0235705 | [act15]: dhkK(D1125N) | dhkK | smbA, sombrero | aberrant cAMP signaling during aggregation, delayed development |
| DBS0235707 | [act15]: dhkK(H825Q) | dhkK | smbA, sombrero | precocious development, small fruiting body |
| DBS0235709 | [act15]: dhkK(H825Q/D1125N) | dhkK | smbA, sombrero | aberrant slug migration, delayed culmination |
| DBS0235712 | dhkK-/[act15]: dhkK(D1125N) | dhkK | smbA, sombrero | aberrant fruiting body morphology |
| DBS0235716 | [act15]: dhkK | dhkK | smbA, sombrero | development arrests at mound stage, precocious aggregation |
| DBS0235706 | regA-/[act15]: dhkK(D1125N) | dhkK, regA | DG1030, DdPDE2, pde2, smbA, sombrero | aberrant fruiting body morphology, precocious development |
| DBS0237205 | [act6]: dia1 | dia1 | DIA-1 | delayed aggregation |
| DBS0235719 | dia1-/[act6]: trap1 | dia1, trap1 | DIA-1, Dd-trap1 | aberrant aggregation, small fruiting body |
| DBS0235903 | dimB-/[act15]: dimA: GFP | dimA, dimB | bzpA, bzpB | abolished nuclear protein localization |
| DBS0235904 | dimB-/[act15]: dimB: GFP | dimB | bzpB | wild type |
| DBS0238511 | drkC-/[act15]: drkC(1-497): YFP | drkC | rk3, vsk3 | decreased phagocytosis |
| DBS0238513 | drkC-/[act15]: drkC(K518R): YFP | drkC | rk3, vsk3 | decreased phagocytosis |
| DBS0238237 | dstA-/GFP: dstA(237-707): ORF+ | dstA | Dd-STATa, STATa | abolished culmination, decreased stalk length |
| DBS0252826 | dstA-/GFP: dstA(237-707): ORF+/[act15]: geneDDB0231646 | dstA, geneDDB0231646 | Dd-STATa, STATa | aberrant fruiting body morphology |
| DBS0252825 | dstA-/GFP: dstA(237-707): ORF+/[act15]: geneDDB0252771 | dstA, geneDDB0252771 | Dd-STATa, STATa | aberrant fruiting body morphology |
| DBS0252816 | dstA-/GFP: dstA(237-707): ORF+/[act15]: hssA | dstA, hssA | Dd-STATa, NK20, STATa | wild type |
| DBS0252822 | dstA-/GFP: dstA(237-707): ORF+/[act15]: hssB | dstA, hssB | Dd-STATa, NK20-like, STATa | wild type |
| DBS0235444 | [act6]: myc: eppA(S250A) | eppA | | decreased growth rate, decreased intracellular cAMP level, delayed development |
| DBS0235445 | [act6]: myc: eppA(S325A) | eppA | | decreased growth rate |
| DBS0235948 | eppA-/[act6]: myc: eppA | eppA | | wild type |
| DBS0237108 | [act15]: fbxA: FLAG | fbxA | chtA | decreased prespore cell differentiation |
| DBS0235662 | [act15]: GFP: forH(1-425) | forH | dDia2, drf2 | aberrant protein localization |
| DBS0235971 | forH-/[act15]: GFP: forH | forH | dDia2, drf2 | decreased cell motility, increased cell-substrate adhesion, increased filopodium formation |
| DBS0235979 | [act15]: fszA: GFP | fszA | FtsZ | increased number of tubular mitochondria |
| DBS0235998 | gbpD-/[act15]: gbpD | gbpD | RapGEF, gefU | aberrant F-actin organization, abolished aggregation, decreased chemotaxis rate, increased cell-substrate adhesion, increased lateral pseudopod formation |
| DBS0237617 | myoI-/[act15]: gbpD | gbpD, myoI | DdMVII, M7, MVII, RapGEF, gefU | aberrant cell morphology, increased cell-substrate adhesion, increased pseudopod formation |
| DBS0237615 | phg2-/[act15]: gbpD | gbpD, phg2 | RapGEF, gefU | aberrant cell morphology, abolished chemotaxis to cAMP, increased pseudopod formation |
| DBS0237614 | rasC-/[act15]: gbpD | gbpD, rasC | RapGEF, gefU | aberrant cell morphology, increased cell-substrate adhesion |
| DBS0237616 | talA-/[act15]: gbpD | gbpD, talA | RapGEF, gefU | aberrant cell morphology, increased cell-substrate adhesion, increased pseudopod formation |
| DBS0237190 | gdt1-/[act15]: pkaR(G135E/G261A) | gdt1, pkaR | PKA, cAK, gdtA, rdeC | abolished aggregation, increased gene expression |
| DBS0237133 | [act15]: GFP: racH: gemA(630-658) | gemA, racH | Miro | delayed cytokinesis |
| DBS0266512 | [act15]: geneDDB0233578 | geneDDB0233578 | | wild type |
| DBS0238390 | gnt15-/[act15]: FLAG: gnt15 | gnt15 | | wild type |
| DBS0238391 | gnt15-/[act15]: FLAG: gnt15 | gnt15 | | wild type |
| DBS0236092 | gpaA-/[gpaA]: gpaA(G45V) | gpaA | Ga1, Galpha1, gpa1 | delayed development |
| DBS0236093 | gpaA-/[gpaA]: gpaA(Q206L) | gpaA | Ga1, Galpha1, gpa1 | increased basal disc size |
| DBS0237136 | [act15]: gpaA | gpaA | Ga1, Galpha1, gpa1 | aberrant cytokinesis, aberrant fruiting body morphology, increased stalk length |
| DBS0237252 | [gpaA]: gpaA(G45V) | gpaA | Ga1, Galpha1, gpa1 | delayed development |
| DBS0237253 | [gpaA]: gpaA(Q206L) | gpaA | Ga1, Galpha1, gpa1 | increased basal disc size |
| DBS0236096 | gpaB-/[act15]: gpaB | gpaB | Ga2, Galpha2, gpa2 | abolished aggregation |
| DBS0236097 | gpaB-/[gpaA]: gpaB | gpaB | Ga2, Galpha2, gpa2 | abolished aggregation |
| DBS0236099 | gpaB-/[gpaB]: gpaB | gpaB | Ga2, Galpha2, gpa2 | wild type |
| DBS0237137 | [act15]: gpaB(D154V)/gpaB- | gpaB | Ga2, Galpha2, gpa2 | decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate |
| DBS0237138 | [act15]: gpaB(E190G)/gpaB- | gpaB | Ga2, Galpha2, gpa2 | decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse |
| DBS0237139 | [act15]: gpaB(I104S)/gpaB- | gpaB | Ga2, Galpha2, gpa2 | decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate |
| DBS0237140 | [act15]: gpaB(L110S)/gpaB- | gpaB | Ga2, Galpha2, gpa2 | decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate |
| DBS0237142 | [act15]: gpaB(N74D)/gpaB- | gpaB | Ga2, Galpha2, gpa2 | decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate |
| DBS0237143 | [act15]: gpaB(R64G)/gpaB- | gpaB | Ga2, Galpha2, gpa2 | decreased chemotaxis rate |
| DBS0237144 | [act15]: gpaB(S155P)/gpaB- | gpaB | Ga2, Galpha2, gpa2 | decreased chemotaxis rate |
| DBS0238866 | grlJ-/[act15]: grlJ: GFP | grlJ | | wild type |
| DBS0238687 | grpA-/[act15]: grpA-FLAG | grpA | GRASP, GRASP55, gorasp2 | wild type |
| DBS0236070 | [act15]: GFP: hcpA | hcpA | | aberrant anaphase, decreased growth rate in suspension |
| DBS0236152 | hcpA?C-GFP | hcpA | | abolished growth on bacterial plates, decreased growth rate in suspension |
| DBS0252821 | [act15]: hssA | hssA | NK20 | wild type |
| DBS0252702 | icmA-/[act15]: TAP: YFP: rasG | icmA-1, icmA-2, rasG | ICMT, ddRASG, icmA | abolished C-terminal protein amino acid methylation |
| DBS0236493 | krsA-/[act15]: GFP: krsA | krsA | Krs1 | wild type |
| DBS0237117 | [act15]: GFP: krsA | krsA | Krs1 | decreased slug migration |
| DBS0238721 | krsA-/[act15]: GFP: krsA | krsA | Krs1 | wild type |
| DBS0238722 | krsA-/[act15]: GFP: krsA(K49R) | krsA | Krs1 | aberrant streaming |
| DBS0238723 | krsA-/[act15]: GFP: krsA(T173A) | krsA | Krs1 | abolished streaming |
| DBS0238724 | krsA-/[act15]: GFP: krsA(deltaKinase) | krsA | Krs1 | abolished streaming |
| DBS0238725 | krsA-/[act15]: GFP: krsA(deltaC) | krsA | Krs1 | aberrant streaming |
| DBS0238726 | krsA-/[act15]: GFP: krsA(deltaNS) | krsA | Krs1 | abolished streaming |
| DBS0237118 | [act15]: GFP: limE | limE | DdLim, crp | aberrant cytokinesis |
| DBS0236549 | mhcA-/[act15]: limE(1-145): GFP | limE, mhcA | DdLim, MHC, crp | increased F-actin polymerization |
| DBS0238218 | [act6]: TAP: GFP: lvsB | lvsB | | wild type |
| DBS0236550 | mhcA-/[act15]: mhcA(T1823A/T1833A/T2029A) | mhcA | MHC | decreased filopodium formation |
| DBS0236551 | mhcA-/[act15]: mhcA(T1823D/T1833D/T2029D) | mhcA | MHC | increased filopodium formation |
| DBS0238157 | mhcA-/[mhcA]: mhcA(1-1224)/[act15]: mhcA(R689H) | mhcA | MHC | decreased actin filament sliding |
| DBS0238158 | mhcA-/[act15]: mhcA(81-2116) | mhcA | MHC | decreased growth rate, development arrests at tipped mound stage |
| DBS0266674 | mhcA-/[act15]: GFP: abpC(9-148) | mhcA | MHC | decreased pseudopod retraction, decreased uropod retraction |
| DBS0266675 | mhcA-/[act15]: GFP: mhcA(E476K) | mhcA | MHC | decreased pseudopod retraction |
| DBS0236548 | mhcA-/[act15]: GFP: pats1(2087-2351) | mhcA, pats1 | MHC | aberrant cytokinesis |
| DBS0236557 | mhkA-/[act15]: mhkA | mhkA | MHCK-A | aberrant cytokinesis, decreased growth rate in suspension, decreased myosin II assembly, development arrests at mound stage |
| DBS0237203 | [act15]: mhkB: FLAG | mhkB | MHCK-B | aberrant cytokinesis, decreased myosin II assembly |
| DBS0238058 | mlcE-/[act15]: myc: mlcE | mlcE | EMLC | wild type |
| DBS0236905 | [act6]: mrps4 | mrps4 | dia3, rps4 | precocious aggregation |
| DBS0236611 | noxA-/[act15]: noxA: myc2 | noxA | gp91phox | aberrant fruiting body morphology |
| DBS0236747 | pefB-/noxA-/[act15]: pefB | noxA, pefB | ALG-2, DdPEF-2, alg-2B, alg2, alg2B, gp91phox, pef2 | aberrant development |
| DBS0237180 | [act15]: nramp1: GFP | nramp1 | NRAMP, Slc11a1 | decreased infection rate by Legionella pneumophila, increased iron ion transport |
| DBS0238362 | p2xA-/[act15]: p2xA: GFP | p2xA | DdP2X | wild type |
| DBS0237182 | [act15]: pakA | pakA | DPAKa, dpak1 | wild type |
| DBS0237183 | [act15]: pakA(K394A) | pakA | DPAKa, dpak1 | delayed development, development arrests at mound stage |
| DBS0237184 | [act15]: pakA[CA] | pakA | DPAKa, dpak1 | abolished aggregation |
| DBS0237185 | [act15]: pakA[G+K] | pakA | DPAKa, dpak1 | wild type |
| DBS0237122 | [act15]: GFP: pats1(2087-2351) | pats1 | | aberrant cytokinesis |
| DBS0237123 | [act15]: GFP: phg2(1-245) | phg2 | | decreased phagocytosis |
| DBS0236484 | [pkaC]: pkaC | pkaC | DdPK2, DdPK3, PK2, PK3, PKA, PKA-C, cAK, pkacat | aberrant fruiting body morphology, decreased intracellular cAMP level, precocious development |
| DBS0237188 | [act15]: pkaR(1-497) | pkaR | PKA, cAK, rdeC | decreased intracellular cAMP level, precocious development, small fruiting body |
| DBS0235442 | [act15]: pldB: GFP | pldB | PLD1 | abolished aggregation |
| DBS0236797 | pldB-/[act15]: pldB: GFP | pldB | PLD1 | abolished aggregation |
| DBS0236825 | ppkA-/[act15]: ppkA | ppkA | DdPPK1, PPK, PPK1 | wild type |
| DBS0238107 | [act15]: FLAG: pppC | ppp4C | PP4C, pppC | wild type |
| DBS0238108 | [act15]: FLAG: pppC(H113Q) | ppp4C | PP4C, pppC | delayed development, development arrests at mound stage |
| DBS0238109 | mekA-/pppC-/[act15]: FLAG: pppC | ppp4C | PP4C, pppC | decreased aggregate size, precocious development |
| DBS0238110 | pppC-/[act15]: smkA | ppp4C, smkA | PP4C, SMEK, pppC | delayed development, development arrests at mound stage |
| DBS0238036 | [AS]proA/proB-/[act15]: proA | proA, proB | | wild type |
| DBS0238037 | [AS]proA/proB-/[act15]: proB | proA, proB | | wild type |
| DBS0238035 | [AS]proA/proB-/[unk]: FLAG: proC | proA, proB, proC | p3 | wild type |
| DBS0238034 | proC-/[unk]: FLAG: proC | proC | p3 | wild type |
| DBS0237289 | [psmC1]: psmC1 | psmC1 | DdTBPalpha | aberrant cytokinesis, delayed gene expression, delayed tip formation |
| DBS0237702 | [act15]: GFP: rac1A | rac1A | | increased filopodium formation, increased membrane ruffling |
| DBS0237703 | [act15]: GFP: rac1B | rac1B | | increased filopodium formation, increased membrane ruffling |
| DBS0237704 | [act15]: GFP: rac1C | rac1C | | increased filopodium formation, increased membrane ruffling |
| DBS0237191 | racC-/[act15]: CFP: racC | racC | | increased chemoattractant-mediated F-actin polymerization |
| DBS0237125 | [act15]: GFP: racG(1-168): racH(164-200) | racG, racH | | decreased chemoattractant-mediated F-actin polymerization, decreased phagocytosis, increased filopodium formation |
| DBS0237128 | [act15]: GFP: racH(1-163): racG(167-201) | racG, racH | | decreased chemoattractant-mediated F-actin polymerization |
| DBS0237130 | [act15]: GFP: racH(M13V) | racH | | aberrant cell morphology, aberrant cytokinesis, increased F-actin polymerization |
| DBS0237132 | [act15]: GFP: racH(T18N) | racH | | aberrant cell morphology, aberrant cytokinesis |
| DBS0238392 | [act15]: GFP: rapA | rapA | rap1 | increased cell-substrate adhesion |
| DBS0238393 | [act15]: GFP: rapA(G12V) | rapA | rap1 | increased cell-substrate adhesion |
| DBS0238394 | [act15]: GFP: rapA(S17N) | rapA | rap1 | decreased cell-substrate adhesion |
| DBS0238396 | [act15]: myc: rapA(G12V) | rapA | rap1 | decreased cell motility, delayed aggregation, increased cell-substrate adhesion |
| DBS0238397 | [act15]: myc: rapA(S17N) | rapA | rap1 | decreased cell-substrate adhesion |
| DBS0238398 | [act15]: myc: rapA | rapA | rap1 | aberrant cell morphology, decreased cell motility, increased cell-substrate adhesion |
| DBS0238395 | talA-/[act15]: rapA(G12V) | rapA, talA | rap1 | increased cell-substrate adhesion |
| DBS0236864 | rasG-/[rasG]: rasB | rasB, rasG | ddRASG | decreased growth rate in suspension |
| DBS0236859 | rasD(G12T) | rasD | Dd-ras, Ddras, ras, rasA | development arrests at mound stage, development arrests at tipped mound stage |
| DBS0237192 | [act15]: rblA | rblA | Rb | increased cell cycle length |
| DBS0237163 | [act15]: myc: rckA(C551A) | rckA | rck1 | decreased chemotaxis rate, delayed slug formation |
| DBS0237164 | [act15]: myc: rckA(E510G) | rckA | rck1 | decreased chemotaxis rate, delayed slug formation |
| DBS0237165 | [act15]: myc: rckA(E510G/N511A) | rckA | rck1 | decreased chemotaxis rate, delayed slug formation |
| DBS0237166 | [act15]: myc: rckA(K867A) | rckA | rck1 | decreased chemotaxis rate, delayed slug formation, precocious aggregation |
| DBS0237167 | [act15]: myc: rckA | rckA | rck1 | delayed development |
| DBS0237179 | [act15]: myr: rckA | rckA | rck1 | decreased chemotaxis rate, delayed development |
| SA604 | [act15]: sgkA: FLAG | sgkA | SK, SPHK | aberrant cytokinesis, increased resistance to carboplatin, increased resistance to cisplatin |
| DBS0238111 | [act15]: HA: smkA | smkA | SMEK | decreased cell polarity, decreased chemotaxis to cAMP, delayed development, small fruiting body |
| DBS0238735 | [act15]: snfA(1-379): GFP | snfA | AMPK?, SNF1, pkraa | aberrant mitochondrion organization and biogenesis, decreased growth rate, decreased phototaxis, decreased stalk length, increased intracellular ATP level, increased number of mitochondria, increased stalk width |
| DBS0237195 | [act15]: spkA: FLAG | spkA-1, spkA-2 | SAPKalpha, spkA | aberrant F-actin organization, aberrant aggregation, decreased cell polarity, decreased chemotaxis rate |
| AK1209 | [act15]: tagA(1-890) | tagA | | multiple tips in mound |
| DBS0236976 | talA- | talA | | aberrant cell morphology, aberrant cytokinesis, decreased cell-substrate adhesion, decreased phagocytosis |
| DBS0237198 | [act15]: torA | torA | | abolished growth |
| DBS0237199 | [act15]: trrA | trrA | trr | aberrant aggregation, decreased growth rate, decreased phagocytosis, delayed culmination |
| DBS0237033 | vasP-/[act15]: GFP: vasP(1-264/285-380) | vasP | | abolished filopodium formation |
| DBS0237037 | vasP-/[act15]: vasP(1-110: 231-380) | vasP | | aberrant cytokinesis, decreased filopodium formation, increased basal F-actin level |
| DBS0237038 | vasP-/[act15]: vasP(1-228) | vasP | | decreased filopodium formation |
| DBS0237039 | vasP-/[act15]: vasP(111-380) | vasP | | increased basal F-actin level, increased filopodium formation |
| DBS0237040 | vasP-/[act15]: vasP | vasP | | decreased filopodium formation |
| DBS0237200 | [act15]: vasP | vasP | | increased basal F-actin level, increased filopodium formation |
| DBS0237840 | vasP-/[act15]: vasP | vasP | | increased basal F-actin level, increased filopodium formation |
| DBS0237836 | vasP-/[act15]: YFP: wipA | vasP, wipA | WIPa | decreased filopodium formation |
| DBS0237842 | vasP-/[act15]: YFP: wipA/[act15]: vasP: FLAG | vasP, wipA | WIPa | increased filopodium formation |
| CW0391 | FLAG-VwkA | vwkA | | aberrant cytokinesis, decreased growth rate in suspension, development arrests at mound stage, increased myosin II assembly, increased protein level |
| DBS0237811 | wasA1-/[tet]: YFP: wasA2/[act15]: wasA(Y33A/W39A/F90A/F91A) | wasA | WASP | decreased F-actin polymerization, decreased F-actin polymerization at the leading edge |
| DBS0237812 | wasA1-/[tet]: YFP: wasA2/[act15]: wasA | wasA | WASP | increased F-actin polymerization at the leading edge |
| DBS0237820 | wasA1-/[tet]: YFP: wasA2/[act15]: wipA | wasA, wipA | WASP, WIPa | abolished chemotaxis |
| DBS0237817 | [act15]: YFP: wipA | wipA | WIPa | increased F-actin polymerization at the leading edge, increased filopodium formation |
| DBS0237819 | [act15]: YFP: wipA(K36A) | wipA | WIPa | increased F-actin polymerization at the leading edge, increased filopodium formation |
| DBS0237821 | [act15]: YFP: wipA(K93A/S95A) | wipA | WIPa | increased F-actin polymerization at the leading edge, increased filopodium formation |
Last updated May 30, 2008
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