Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains - Null - Overexpression - Multiple - Other - Developmental

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Systematic Name	Strain Descriptor	Associated gene(s)	Phenotypes
DBS0350657	[csaA]: csaA	csaA	aberrant aggregation | increased calcium-independent cell-cell adhesion
DBS0351382	myoB-/ [act15]: GFP: myoB(1-921,1057-1111)	myoB	abolished protein localization
DBS0235594	CHE10	cbpC	decreased slug migration | precocious aggregation | decreased aggregate size | decreased fruiting body size | delayed culmination
DBS0266719	Dd5P4-/ [act15]: Dd5P4: GFP	Dd5P4	wild type
DBS0266695	Dd5P4-/ [act15]: GAP5P4	Dd5P4	decreased growth rate | multiple tips in mound
DBS0351414	Dd5P4-/ [act15]: GFP: Dd5P4(D319G)	Dd5P4	increased contractile vacuole size | aberrant contractile vacuole discharge | aberrant protein localization
DBS0266720	Dd5P4-/ [act15]: Hs-OCRL	Dd5P4	decreased phagocytosis
DBS0266721	Dd5P4-/ [act15]: Hs-OCRL(D422A)	Dd5P4	decreased phagocytosis
DBS0266694	Dd5P4-/ [act15]: cat5P4	Dd5P4	decreased growth rate | multiple tips in mound
CW0391	FLAG-VwkA	vwkA	increased myosin II assembly | decreased growth rate | aberrant cytokinesis | development arrests at mound stage | aberrant hypotonic response | increased protein level
CW0368	GFP-VwkA	vwkA	decreased growth rate | aberrant cytokinesis
DBS0350102	GFP: pcp	pcp	aberrant contractile vacuole morphology | aberrant hypotonic response
DBS0236358	HR42	fbxA	abolished culmination | decreased sporulation
DBS0351312	HSPC300-/ [act15]: abpB(129-295)	abpB | hspc300	aberrant cellular process
DBS0237044	VatMpr/ [act15]: vatM	vatM	wild type
DBS0237042	VatMpr/ [act15]: vatM: GFP	vatM	decreased growth rate
DBS0351311	[AS]proA/ abpB(129-295)	abpB | proA	aberrant cellular process
DBS0238036	[AS]proA/ proB-/ [act15]: proA	proA | proB	wild type
DBS0238037	[AS]proA/ proB-/ [act15]: proB	proA | proB	wild type
DBS0238035	[AS]proA/ proB-/ [unk]: FLAG: proC	proA | proB | proC	wild type
DBS0237274	[OE]: chlim	ChLim	increased basal F-actin level | decreased phagocytosis | decreased growth rate
DBS0350519	[OE]: egeA	egeA	decreased protein level | abolished aggregation
DBS0237275	[OE]: gbfA	gbfA	precocious gene expression
JH258	[OE]: gpaE	gpaE	precocious tip formation | precocious gene expression
DBS0348921	[OE]: ipkA1	ipkA1	aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression
DBS0348922	[OE]: itpk1	itpk1	aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression
DBS0236962	[OE]: pdiA	pdiA	delayed aggregation
DBS0237015	[OE]: pdiA	pdiA	aberrant tip formation | abolished slug formation | abolished culmination
DBS0302681	[OE]: sgcA(878-2843): GFP/ sgcA-	gcA | sgcA	aberrant chemotaxis to cAMP | decreased chemotaxis rate
DBS0302682	[OE]: sgcA(N1106A): GFP/ gca-/ sgcA-	gcA | sgcA	aberrant streaming | aberrant chemotaxis to cAMP | increased lateral pseudopod formation | decreased chemotaxis rate
DBS0266621	[OE]mipp1	mipp1	aberrant inositol phosphate metabolic process | aberrant gene expression | increased response to lithium
DBS0349923	[RNAi]ctnnA/ [act15]: GFP-mhcA	ctnnA	aberrant stalk morphogenesis | aberrant protein localization
DBS0350924	[TRE-Pmin]: 6xHis: GFP: dhcA(1384-4725(K1975T))	dhcA	aberrant molecular function
DBS0350052	[TRE-Pmin]: arfA(Q71L): GFP	arfA	aberrant filopodium formation | aberrant cytokinesis
DBS0350053	[TRE-Pmin]: arfA(T31N): GFP	arfA	wild type | increased defense response to Gram-negative bacterium
DBS0351202	[act15]: 6xHis: amd1: eYFP	amd1	decreased gene expression | increased gene expression | aberrant vegetative growth | delayed development | cell cycle arrest | aberrant fruiting body morphology
DBS0351167	[act15]: 6xHis: ei24: eYFP	ei24	aberrant aggregation | increased intracellular cAMP level | increased chemotaxis to cAMP | aberrant cell cycle | increased sporulation
DBS0350674	[act15]: 6xHis: erkA	erkA	aberrant slug formation
DBS0351253	[act15]: 6xHis: sesn: eYFP	sesn	aberrant aggregation | decreased protein level | increased gene expression | decreased growth rate | aberrant response to oxidative stress
DBS0349845	[act15]: 7xHis: myoK: Ty1	myoK	aberrant cortical actin cytoskeleton stabilization | aberrant engulfment during phagocytosis | aberrant cell morphology
DBS0237100	[act15]: CFP: racC(G15V)	racC	increased basal F-actin level
DBS0266512	[act15]: DDB_G0272656	sigN4	wild type
DBS0350049	[act15]: FLAG: cycC	cycC	precocious tip formation
DBS0350321	[act15]: FLAG: hbx4	hbx4	aberrant aggregation | abolished gene expression | abolished slug migration | decreased growth rate | aberrant cytokinesis
DBS0350322	[act15]: FLAG: hbx4/ [act15]: cadA	cadA | hbx4	wild type
DBS0350325	[act15]: FLAG: hbx4/ [ecmAO]: lacZ	hbx4	decreased spore germination | aberrant gene expression | increased prestalk cell differentiation
DBS0351294	[act15]: FLAG: mybB	mybB	increased gene expression | precocious development
DBS0238107	[act15]: FLAG: ppp4C	ppp4c	wild type
DBS0238108	[act15]: FLAG: ppp4C(H113Q)	ppp4c	development arrests at mound stage | delayed development
DBS0351488	[act15]: FLAG: rasC(Q62L)	rasC	abolished protein localization to plasma membrane | increased F-actin polymerization | decreased chemotaxis to cAMP
DBS0351292	[act15]: FLAG: sir2A	sir2A	delayed development
DBS0351293	[act15]: FLAG: sir2C	sir2C	delayed development
DBS0351291	[act15]: FLAG: sir2D	sir2D	increased gene expression | precocious development
DBS0304572	[act15]: GFP: abpD(1441-1736)	abpD	abolished localization to nuclear envelope
DBS0304571	[act15]: GFP: abpD(1441-1738)	abpD	abolished protein localization to nuclear envelope | abolished localization to nuclear envelope
DBS0304573	[act15]: GFP: abpD(1441-1738,1737P/ A)	abpD	abolished localization to nuclear envelope
DBS0237114	[act15]: GFP: abpE(413-481)	abpE-1 | abpE-2	increased lateral pseudopod formation
DBS0351483	[act15]: GFP: aqpB(1-208,219-294)	aqpB	decreased hypotonic response
DBS0351097	[act15]: GFP: cbpG	cbpG	increased cell size | increased cell-substrate adhesion | decreased chemotaxis to cAMP | abolished aggregation
DBS0350593	[act15]: GFP: cepL	cepL	decreased cell polarity | decreased growth rate | decreased phagocytosis | increased cell size | increased cell-substrate adhesion | aberrant centrosome localization
DBS0350594	[act15]: GFP: cepL(1-1114)	cepL	increased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis
DBS0350595	[act15]: GFP: cepL(1-763)	cepL	increased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis
DBS0350596	[act15]: GFP: cepL(763-1114)	cepL	development arrests at loose mound stage | delayed aggregation | increased cell-substrate adhesion | decreased chemotaxis rate | increased growth rate | abolished cell polarity | aberrant phototaxis | delayed gene expression | decreased cell size
DBS0350460	[act15]: GFP: docD	docD	increased pseudopod formation | increased F-actin polymerization | increased cell motility
DBS0350288	[act15]: GFP: forF(1-1087)	forF	decreased pinocytosis | decreased phagocytosis | decreased growth rate
DBS0235662	[act15]: GFP: forH(1-425)	forH	abolished localization to pseudopodium
DBS0350984	[act15]: GFP: frmB	frmB	aberrant stalk formation | decreased spore size
DBS0304973	[act15]: GFP: gefQ(173-651,818-1298)	gefQ	increased Ras guanyl-nucleotide exchange factor activity
DBS0304971	[act15]: GFP: gefQ(683-833)	gefQ	decreased Ras guanyl-nucleotide exchange factor activity
DBS0304972	[act15]: GFP: gefQ(910-1298)	gefQ	aberrant cytokinesis | aberrant phototaxis
DBS0351254	[act15]: GFP: gflB	gflB	decreased substrate adhesion-dependent cell spreading | decreased F-actin polymerization | increased cell motility
DBS0350422	[act15]: GFP: gpbB	gpbB	aberrant vegetative growth | delayed development
DBS0350349	[act15]: GFP: gtaC(1-467: 497-587)	gtaC	abolished localization to nucleus
DBS0350351	[act15]: GFP: gtaC(229-587)	gtaC	abolished localization to cytoplasm
DBS0350359	[act15]: GFP: gtaC(281-467: 497-587)	gtaC	aberrant localization to cytoplasm
DBS0350352	[act15]: GFP: gtaC(281-587)	gtaC	abolished localization to cytoplasm
DBS0350360	[act15]: GFP: gtaC(346-467: 497-587)	gtaC	aberrant cellular localization
DBS0350353	[act15]: GFP: gtaC(346-587)	gtaC	abolished localization to cytoplasm
DBS0350350	[act15]: GFP: gtaC(K469,470,494,496A/ R468,471A)	gtaC	abolished localization to nucleus
DBS0236070	[act15]: GFP: hcpA	hcpA	decreased growth rate | aberrant anaphase
DBS0237117	[act15]: GFP: krsA	krsA	decreased slug migration
DBS0237118	[act15]: GFP: limE	limE	aberrant cytokinesis
DBS0351530	[act15]: GFP: lis1	lis1	decreased phagocytosis | decreased chemotaxis to folate
DBS0349983	[act15]: GFP: lmnB	lmnB	aberrant chromatin assembly
DBS0350490	[act15]: GFP: mhcA(T1823D/ T1833D/ T2029D)/ AX3	mhcA	decreased growth rate | aberrant localization
DBS0350852	[act15]: GFP: nkaP	nkaP	aberrant aggregation | decreased gene expression | increased gene expression | aberrant vegetative growth | increased chemotaxis rate
DBS0350338	[act15]: GFP: pakA	pakA	increased phagocytosis
DBS0350337	[act15]: GFP: pakA(797-1197)	pakA	decreased phagocytosis | decreased cell motility
DBS0237122	[act15]: GFP: pats1(2087-2351)	pats1	aberrant cytokinesis
DBS0237123	[act15]: GFP: phg2(1-245)	phg2	decreased phagocytosis
DBS0235442	[act15]: GFP: pldB	pldB	abolished aggregation
DBS0237702	[act15]: GFP: rac1A	rac1A	increased filopodium formation | increased membrane ruffling | increased macropinocytosis | increased growth rate | increased cell motility
DBS0351073	[act15]: GFP: rac1A(G12V)	rac1A	decreased growth rate | aberrant F-actin organization | decreased phagocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | delayed development | abolished filopodium formation
DBS0351075	[act15]: GFP: rac1A(T17N)	rac1A	aberrant filopodium formation
DBS0237703	[act15]: GFP: rac1B	rac1B	increased filopodium formation | increased membrane ruffling
DBS0237704	[act15]: GFP: rac1C	rac1C	increased filopodium formation | increased membrane ruffling | increased growth rate | increased cell motility
DBS0351074	[act15]: GFP: rac1C(G12V)	rac1C	decreased growth rate | aberrant F-actin organization | decreased phagocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | delayed development | abolished filopodium formation
DBS0351076	[act15]: GFP: rac1C(T17N)	rac1C	aberrant filopodium formation
DBS0237125	[act15]: GFP: racG(1-168): racH(164-200)	racG | racH	increased filopodium formation | decreased chemoattractant-mediated F-actin polymerization | decreased phagocytosis
DBS0237128	[act15]: GFP: racH(1-163): racG(167-201)	racG | racH	decreased chemoattractant-mediated F-actin polymerization
DBS0237130	[act15]: GFP: racH(M13V)	racH	increased F-actin polymerization | aberrant cytokinesis | aberrant cell morphology
DBS0237132	[act15]: GFP: racH(T18N)	racH	aberrant cytokinesis | aberrant cell morphology
DBS0237133	[act15]: GFP: racH: gemA(630-658)	gemA | racH	delayed cytokinesis
DBS0238392	[act15]: GFP: rapA	rapA	increased cell-substrate adhesion
DBS0238393	[act15]: GFP: rapA(G12V)	rapA	increased cell-substrate adhesion
DBS0238394	[act15]: GFP: rapA(S17N)	rapA	decreased cell-substrate adhesion
DBS0237134	[act15]: GFP: sbds	sbds	wild type
DBS0237135	[act15]: GFP: sbds	sbds	wild type
DBS0351177	[act15]: GFP: sey1	sey1	aberrant vacuole organization and biogenesis
DBS0350715	[act15]: GFP: src1(2-646)	src1	aberrant nuclear envelope morphology
DBS0304563	[act15]: GFP: sun1(283-905)	sun1	increased number of centrosomes | decreased protein localization to nuclear envelope | increased cell size | aberrant nucleus morphology | aberrant perinuclear space | aberrant centrosome localization | aberrant sister chromosome segregation
DBS0350441	[act15]: GFP: talA/ mhcA-/ talA-	mhcA | talA	aberrant protein localization
DBS0350648	[act15]: HA: Rab14(N121I)	rab14	decreased pinocytosis | decreased hypotonic response | aberrant contractile vacuole morphology
DBS0350899	[act15]: HA: rab11(N126I)	rab11A	aberrant contractile vacuole organization and biogenesis | aberrant contractile vacuole morphology
DBS0350812	[act15]: HA: rab7A(Q67L)	rab7A	increased exocytosis
DBS0350813	[act15]: HA: rab7A(T22N)	rab7A	decreased pinocytosis | increased secretion of lysosomal enzyme | decreased exocytosis | decreased phagocytosis | aberrant phagosome maturation | abolished protein localization | abolished macropinocytosis
DBS0238111	[act15]: HA: smkA	smkA	decreased cell polarity | delayed development | decreased fruiting body size | decreased chemotaxis to cAMP
DBS0350429	[act15]: RFP: abpE	abpE-1 | abpE-2	delayed aggregation
DBS0350867	[act15]: RFP: mtpn	mtpn	increased filopodium formation | decreased protein localization to cell cortex | aberrant F-actin organization | decreased pseudopod size
DBS0351228	[act15]: T7: rasG(G12T)	rasG	increased protein phosphorylation | decreased growth rate | decreased phagocytosis | increased cell-substrate adhesion | decreased filopodium formation
DBS0351226	[act15]: YFP: iqgC	iqgC	decreased phagocytosis | decreased macropinocytosis
DBS0350986	[act15]: YFP: myoC(G395A)	myoC	decreased pinocytosis | decreased phagocytosis | aberrant spindle stabilization
DBS0237817	[act15]: YFP: wipA	wipA	increased filopodium formation | increased F-actin polymerization at the leading edge
DBS0237819	[act15]: YFP: wipA(K36A)	wipA	increased filopodium formation | increased F-actin polymerization at the leading edge
DBS0237821	[act15]: YFP: wipA(K93A/ S95A)	wipA	increased filopodium formation | increased F-actin polymerization at the leading edge
DBS0350673	[act15]: abpC: GFP	abpC	decreased cell motility
DBS0304574	[act15]: abpD	abpD	abolished protein localization to nuclear envelope
DBS0237096	[act15]: abpE	abpE-1 | abpE-2	aberrant aggregation | increased lateral pseudopod formation | decreased cell motility | delayed development | decreased fruiting body size
DBS0350800	[act15]: adprt1A	adprt1A	decreased extracellular cAMP level | increased gene expression | decreased gene expression | delayed aggregation | aberrant cell cycle | decreased growth rate | decreased intracellular ATP level | aberrant response to oxidative stress | decreased intracellular cAMP level | increased mitochondrial fission
DBS0238086	[act15]: atg1	atg1	wild type
DBS0238091	[act15]: atg1(1-628)	atg1	wild type
DBS0238088	[act15]: atg1(K36A)	atg1	abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238090	[act15]: atg1(K36A/ 1-628)	atg1	wild type
DBS0350008	[act15]: bzpN: GFP	bzpN	decreased growth rate | abolished negative regulation of vegetative growth
JK1	[act15]: carA	carA-1 | carA-2	delayed aggregation
DBS0252737	[act15]: carA(I104A)	carA-1 | carA-2	decreased cAMP binding
DBS0252732	[act15]: carA(I104C)	carA-1 | carA-2	decreased protein kinase activation
DBS0252740	[act15]: carA(I104D)	carA-1 | carA-2	increased cAMP binding | delayed aggregation | decreased protein kinase activation | aberrant cAMP wave formation
DBS0252744	[act15]: carA(I104E)	carA-1 | carA-2	increased cAMP binding | delayed aggregation | aberrant cAMP wave formation
DBS0252741	[act15]: carA(I104F)	carA-1 | carA-2	increased cAMP binding | decreased protein kinase activation
DBS0252738	[act15]: carA(I104G)	carA-1 | carA-2	increased cAMP binding | decreased protein kinase activation
DBS0252747	[act15]: carA(I104H)	carA-1 | carA-2	development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | abolished cAMP wave formation
DBS0252749	[act15]: carA(I104K)	carA-1 | carA-2	increased cAMP binding | decreased protein kinase activation | abolished aggregation | abolished cAMP wave formation
DBS0252739	[act15]: carA(I104L)	carA-1 | carA-2	wild type
DBS0252742	[act15]: carA(I104M)	carA-1 | carA-2	increased cAMP binding
DBS0252746	[act15]: carA(I104N)	carA-1 | carA-2	development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | abolished cAMP wave formation
DBS0252734	[act15]: carA(I104P)	carA-1 | carA-2	decreased protein kinase activation
DBS0252745	[act15]: carA(I104Q)	carA-1 | carA-2	development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | abolished cAMP wave formation
DBS0252750	[act15]: carA(I104R)	carA-1 | carA-2	development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | abolished cAMP wave formation
DBS0252743	[act15]: carA(I104S)	carA-1 | carA-2	increased cAMP binding | decreased protein kinase activation | aberrant cAMP wave formation
DBS0252735	[act15]: carA(I104T)	carA-1 | carA-2	increased cAMP binding | aberrant cAMP wave formation
DBS0252736	[act15]: carA(I104V)	carA-1 | carA-2	wild type
DBS0252733	[act15]: carA(I104W)	carA-1 | carA-2	increased cAMP binding
DBS0252748	[act15]: carA(I104Y)	carA-1 | carA-2	development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | aberrant cAMP wave formation
DBS0351055	[act15]: catA	catA	decreased slug migration | decreased superoxide production | decreased fruiting body size | decreased sporulation
DBS0302445	[act15]: cfaD	cfaD	decreased growth rate | aberrant fruiting body morphology
DBS0350333	[act15]: cnrF: GFP	cnrF	aberrant regulation of GTPase activity
DBS0302658	[act15]: cnrN: myc/ smlA-	cnrN | smlA	decreased fruiting body size
DBS0237102	[act15]: cofA	cofA	increased actin bundle formation | increased membrane ruffling | increased cell motility
DBS0350583	[act15]: csaA	csaA	decreased cell-substrate adhesion | precocious aggregation | increased calcium-independent cell-cell adhesion
DBS0349864	[act15]: cyrA: GFP	cyrA	increased chemotaxis to cAMP
DBS0237104	[act15]: dagA	dagA	wild type
DBS0350978	[act15]: deeJ	deeJ	increased pinocytosis | increased growth rate | increased phagocytosis
DBS0237106	[act15]: dhkC(394-661)	dhkC	development arrests at slug stage | increased slug migration
DBS0235716	[act15]: dhkK	dhkK	precocious aggregation | development arrests at mound stage
DBS0235705	[act15]: dhkK(D1125N)	dhkK	aberrant cAMP signaling during aggregation | delayed development
DBS0235707	[act15]: dhkK(H825Q)	dhkK	precocious development | decreased fruiting body size
DBS0235709	[act15]: dhkK(H825Q/ D1125N)	dhkK	aberrant slug migration | delayed culmination
DBS0237108	[act15]: fbxA: FLAG	fbxA	decreased prespore cell differentiation
DBS0350365	[act15]: fip(1163-2038)	fip-1 | fip-2	aberrant prestalk 0 cell differentiation
DBS0350012	[act15]: fps: GFP	fps	increased resistance to bisphosphonate
DBS0235979	[act15]: fszA: GFP	fszA	increased number of tubular mitochondria
DBS0351485	[act15]: fszB: GFP	fszB	decreased mitochondrial fusion | decreased mitochondrial fission
DBS0351056	[act15]: gcsA	gcsA	increased catalytic activity | decreased slug migration | decreased superoxide production | aberrant gene expression | decreased fruiting body size | decreased sporulation
DBS0237136	[act15]: gpaA	gpaA	increased stalk length | aberrant cytokinesis | aberrant fruiting body morphology
DBS0351058	[act15]: gpaB	gpaB	aberrant aggregation | abolished sporulation | aberrant F-actin polymerization | decreased cell polarity | increased intracellular cAMP level | development arrests at mound stage | aberrant protein localization to plasma membrane | increased prestalk cell differentiation
DBS0350680	[act15]: gpaE	gpaE	abolished growth | decreased chemotaxis to folate
DBS0237145	[act15]: gpaG	gpaG	aberrant fruiting body morphology
DBS0237146	[act15]: gpaH	gpaH	wild type
DBS0350971	[act15]: gpaH/ AX2	gpaH	aberrant cytokinesis | decreased growth rate | aberrant spore germination | increased cell-substrate adhesion | increased cell-cell adhesion | aberrant development
DBS0350079	[act15]: grlB	grlB	delayed aggregation
DBS0351054	[act15]: gshB	gshB	aberrant aggregation | abolished sporulation | aberrant F-actin polymerization | decreased cell polarity | increased intracellular cAMP level | increased gene expression | development arrests at mound stage | increased prestalk cell differentiation
DBS0351059	[act15]: gshB/ [AS]gpaB	gpaB | gshB	aberrant streaming | decreased cell polarity | decreased sporulation
DBS0350989	[act15]: gst4	gst4	increased fruiting body size
DBS0236152	[act15]: hcpA(1-161: 218-225): GFP	hcpA	decreased growth rate
DBS0252821	[act15]: hssA	hssA	wild type
DBS0351173	[act15]: htrA(S300A)	htrA	decreased growth rate | aberrant fruiting body morphology
DBS0351282	[act15]: htt: eYFP	htt	decreased gene expression | increased gene expression
DBS0350037	[act15]: mekA(299-360)	mekA	decreased aggregate size
DBS0350034	[act15]: mekA(K321A)	mekA	decreased aggregate size
DBS0350033	[act15]: mekA(S444A/ T448A)	mekA	decreased aggregate size
DBS0237203	[act15]: mhkB: FLAG	mhkB	aberrant cytokinesis | decreased myosin II assembly
DBS0350026	[act15]: mip1/ [act15]: mekA: FLAG	mekA | mip1-1 | mip1-2	aberrant protein localization to nucleus
DBS0350331	[act15]: mkpA: GFP: TAP	mkpA	increased resistance to cisplatin
DBS0350330	[act15]: mkpB: GFP: TAP	mkpB-1 | mkpB-2	increased resistance to cisplatin
DBS0237162	[act15]: myc-cdk8	cdk8	multiple tips | precocious tip formation
DBS0350050	[act15]: myc: cdk8/ [act15]: FLAG: cycC	cdk8 | cycC	precocious tip formation
DBS0266837	[act15]: myc: ptpC	ptpC	aberrant signal transduction during aggregation | aberrant hypertonic response | aberrant protein localization
DBS0350417	[act15]: myc: ptpC	ptpC	aberrant protein phosphorylation
DBS0266839	[act15]: myc: ptpCΔ(C649S)	ptpC	aberrant protein localization to nucleus | increased protein tyrosine phosphorylation
DBS0266838	[act15]: myc: ptpC(C649S)	ptpC	aberrant protein localization to nucleus | increased protein tyrosine phosphorylation
DBS0238398	[act15]: myc: rapA	rapA	increased cell-substrate adhesion | decreased cell motility | aberrant cell morphology
DBS0238396	[act15]: myc: rapA(G12V)	rapA	increased protein localization to cell cortex | delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation
DBS0238397	[act15]: myc: rapA(S17N)	rapA	decreased cell-substrate adhesion
DBS0237167	[act15]: myc: rckA	rckA	delayed development
DBS0237163	[act15]: myc: rckA(C551A)	rckA	delayed slug formation | decreased chemotaxis rate
DBS0237164	[act15]: myc: rckA(E510G)	rckA	delayed slug formation | decreased chemotaxis rate
DBS0237165	[act15]: myc: rckA(E510G/ N511A)	rckA	delayed slug formation | decreased chemotaxis rate
DBS0237166	[act15]: myc: rckA(K867A)	rckA	delayed slug formation | precocious aggregation | decreased chemotaxis rate
DBS0350132	[act15]: myc: splB	splB	increased protein localization to nucleus | increased protein tyrosine phosphorylation
DBS0351051	[act15]: myc: talA(2255-2492)/ puf118(677-1036)	puf118 | talA	aberrant chemotaxis to cAMP | aberrant protein localization
DBS0351359	[act15]: myoB	myoB	decreased pinocytosis | increased localization to cell cortex | delayed aggregation | decreased growth rate | aberrant F-actin organization | decreased cell motility | delayed development | decreased fruiting body size
DBS0351037	[act15]: myoE(1-1005)	myoE	abolished phosphoinositide binding
DBS0351036	[act15]: myoE(K859A/ K863A/ R868A/ R869A): GFP	myoE	abolished phosphoinositide binding | abolished localization to plasma membrane
DBS0349847	[act15]: myoK: Myc	myoK	decreased phagocytosis
DBS0237179	[act15]: myr: rckA	rckA	delayed development | decreased chemotaxis rate
DBS0349860	[act15]: ndkC	ndkC-1 | ndkC-2	decreased exocytosis | decreased pinocytosis | decreased phagocytosis | decreased growth rate | increased growth rate
DBS0237180	[act15]: nramp1: GFP	nramp1	increased defense response to Gram-negative bacterium | increased iron ion transport
DBS0350858	[act15]: odc	odc	aberrant cellular metabolic process | aberrant cell cycle
DBS0351201	[act15]: odc: eYFP	odc	decreased growth rate | delayed development
DBS0237182	[act15]: pakA	pakA	wild type
DBS0237183	[act15]: pakA(K394A)	pakA	development arrests at mound stage | delayed development
DBS0237184	[act15]: pakA[CA]	pakA	abolished aggregation
DBS0237185	[act15]: pakA[G+K]	pakA	wild type
DBS0351186	[act15]: phr2ab: GFP	phr2aB	aberrant cytokinesis | aberrant centrosome organization
DBS0349903	[act15]: pisA	pisA	decreased slug migration | aberrant tip formation | delayed aggregation | decreased fruiting body size
DBS0349902	[act15]: pisA: GFP	pisA	decreased slug migration | increased gene expression | decreased gene expression | delayed aggregation | delayed development | decreased phototaxis
DBS0350693	[act15]: pkaC	pkaC	precocious development
DBS0237188	[act15]: pkaC(1-497)	pkaC	precocious development | decreased intracellular cAMP level | decreased fruiting body size
DBS0235418	[act15]: pkaR	pkaR	aberrant response to abiotic stimulus
DBS0237189	[act15]: pkaR(G135E/ G261A)	pkaR	decreased protein tyrosine phosphorylation | decreased cAMP binding | decreased protein kinase activity | abolished aggregation | abolished cAMP-induced cAMP pulse
DBS0350701	[act15]: pkaR(G135E/ G261A)/ AX3	pkaR	decreased gene expression | abolished cAMP-induced cAMP pulse
DBS0350609	[act15]: pkaR(S133T,G135E)	pkaR	decreased cAMP binding | decreased protein kinase activity | abolished aggregation | abolished cAMP-induced cAMP pulse
DBS0350920	[act15]: pkcA	pkcA	increased catalytic activity | abolished aggregation
DBS0235538	[act15]: pldB	pldB	decreased F-actin polymerization | increased catalytic activity | increased exocytosis | aberrant chemotaxis to cAMP | abolished aggregation | decreased sporulation
DBS0349874	[act15]: psaA: GFP	psaA	aberrant sporulation
DBS0350751	[act15]: pten(16-515): GFP	pten	abolished catalytic activity
DBS0350750	[act15]: pten(186-515): GFP	pten	abolished catalytic activity
DBS0350752	[act15]: pten(C124S): GFP	pten	abolished catalytic activity
DBS0350753	[act15]: pten(G129E): GFP	pten	abolished catalytic activity
DBS0350318	[act15]: rab11A: RFP	rab11A	aberrant contractile vacuole organization and biogenesis | decreased contractile vacuole size | abolished hypotonic response
DBS0350951	[act15]: rac1B(Q61L)	rac1B	aberrant F-actin organization | increased lateral pseudopod formation | decreased chemotaxis to cAMP
DBS0350952	[act15]: rac1B(T17N)	rac1B	aberrant F-actin organization | delayed aggregation | abolished cell polarity | abolished chemotaxis to cAMP
DBS0350469	[act15]: racE(G20V): GFP	racE	decreased F-actin polymerization | aberrant cytokinesis | decreased growth rate
DBS0351497	[act15]: rasD(Q61L)	rasD	decreased protein kinase activation
DBS0351496	[act15]: rasD(S17N)	rasD	increased protein kinase activation
DBS0351212	[act15]: rasG(S17N)	rasG	aberrant activation of GTPase activity | decreased chemotaxis to cAMP
DBS0350262	[act15]: rbg3	rbg3	increased lysosome size | decreased growth rate | delayed development
DBS0237192	[act15]: rblA	rblA	increased cell cycle length
DBS0349938	[act15]: rgaA	rgaA	aberrant cytokinesis | decreased cell motility | decreased basal F-actin level
DBS0351529	[act15]: rgbA(751-1072,1080-1284,1517-1846)	rgbA	aberrant macropinocytosis | abolished protein localization
DBS0351528	[act15]: rgbA(751-1072,1121-1317,1505-1834)	rgbA	aberrant macropinocytosis | abolished protein localization
DBS0351304	[act15]: rheb	rheb	decreased phagocytosis | decreased macropinocytosis | increased growth rate
DBS0350294	[act15]: rheb: YFP	rheb	increased cell size
DBS0350890	[act15]: rnp1A	rnp1A	increased resistance to nocodazole
DBS0350575	[act15]: rps4	rps4	decreased spore germination | aberrant actin cytoskeleton organization | aberrant vegetative growth | decreased spore size | decreased aggregate size | aberrant fruiting body morphology | decreased sporulation
DBS0236915	[act15]: rzpA	rzpA	increased gene expression | decreased gene expression | delayed culmination
DBS0349793	[act15]: sadA(921-952)	sadA	decreased cell-substrate adhesion
SA604	[act15]: sgkA: FLAG	sgkA	aberrant response to abiotic stimulus | increased resistance to cisplatin | aberrant cytokinesis | increased resistance to carboplatin
HPF437	[act15]: snfA(1-379): GFP	snfA	increased stalk width | increased intracellular ATP level | decreased growth rate | increased number of mitochondria | decreased defense response to bacterium | decreased phototaxis | decreased stalk length | aberrant mitochondrion organization
DBS0351040	[act15]: snfA(1-379): GFP/ [AS]ndkC-1	ndkC-1 | ndkC-2 | snfA	wild type
DBS0350976	[act15]: snfA: YFP	snfA	decreased growth rate | aberrant fruiting body morphology
DBS0351053	[act15]: sod2	sod2	decreased slug migration | decreased superoxide production | decreased fruiting body size | decreased sporulation
DBS0304457	[act15]: sodA/ gcsA-	gcsA | sodA	wild type
DBS0237194	[act15]: sodA: myc	sodA	aberrant response to abiotic stimulus | decreased gene expression | abolished aggregation
DBS0237195	[act15]: spkA: FLAG	spkA-1 | spkA-2	aberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
AK1209	[act15]: tagA(1-890)	tagA	multiple tips in mound
DBS0350962	[act15]: tor(212-2380): YFP	tor	decreased growth rate | aberrant development
DBS0237198	[act15]: torA	torA	abolished growth
DBS0350862	[act15]: tpt1: YFP	tpt1	decreased growth rate
DBS0237199	[act15]: trrA	trrA	aberrant aggregation | decreased growth rate | decreased phagocytosis | delayed culmination
DBS0237200	[act15]: vasP	vasP	increased filopodium formation | increased basal F-actin level
DBS0351184	[act15]: washc5(N457D): GFP	washc5	aberrant cytokinesis
DBS0351183	[act15]: washc5: GFP	washc5	aberrant cytokinesis
DBS0350911	[act6]: GFP: cepA/ cepA(183-346)	cepA	increased number of centrosomes
DBS0351235	[act6]: GFP: cepL	cepL	increased number of microtubule-organizing centers
DBS0349984	[act6]: GFP: lmnB(1-712)	lmnB	abolished growth | decreased resistance to fluid shear stress
DBS0350497	[act6]: GFP: rab2A	rab2A	decreased phagocytosis | aberrant hypotonic response | increased growth rate
DBS0350499	[act6]: GFP: rab2A(Q64L)	rab2A	decreased autophagic cell death | aberrant cell-cell adhesion | aberrant hypotonic response | increased growth rate | increased phagocytosis
DBS0306243	[act6]: GFP: sun1	sun1	increased number of centrosomes | aberrant nucleus morphology | aberrant sister chromosome segregation | aberrant centromere complex assembly | aberrant centrosome organization
DBS0306244	[act6]: GFP: sun1(1-722)	sun1	increased number of centrosomes | aberrant nucleus morphology | aberrant sister chromosome segregation | aberrant centromere complex assembly | aberrant centrosome organization
DBS0350685	[act6]: csaA	csaA	increased slug size | increased calcium-independent cell-cell adhesion
DBS0237205	[act6]: dia1	dia1	delayed aggregation
DBS0236905	[act6]: mrps4	mrps4	precocious aggregation
DBS0235444	[act6]: myc: eppA(S250A)	eppA	decreased growth rate | delayed development | decreased intracellular cAMP level
DBS0235445	[act6]: myc: eppA(S325A)	eppA	decreased growth rate
DBS0266836	[act6]: ptpB	ptpB	delayed aggregation | decreased fruiting body size
DBS0350807	[act6]: rabS(N137I): GFP	rabS	aberrant contractile vacuole organization and biogenesis | increased secretion of lysosomal enzyme | increased endocytic recycling | aberrant hypertonic response
DBS0350806	[act6]: rabS: GFP	rabS	decreased cell-cell adhesion | increased secretion of lysosomal enzyme | increased cell death | increased pinocytosis | aberrant hypertonic response | decreased chemotaxis to cAMP | aberrant development | increased growth rate | increased phagocytosis
DBS0350982	[act6]: rps6	rps6	aberrant cytokinesis | delayed development
DBS0304410	[act6]: srsA	srsA	increased aggregate size | decreased gene expression | increased slug size | delayed aggregation | decreased sporulation | aberrant fruiting body morphology
DBS0237220	[act6]: trap1	trap1	development arrests at loose mound stage | aberrant aggregation | abolished pinocytosis | increased gene expression | decreased gene expression | decreased growth rate
DBS0350695	[act6]: yakA	yakA	increased gene expression | abolished growth
DBS0350069	[act6]: zizB: GFP	zizB	aberrant cell separation during cytokinesis | increased filopodium formation
DBS0304460	[act]: alrA/ gcsA-	alrA | gcsA	wild type
DBS0349955	[ampA]: RFP: ampA	ampA	development arrests at mound stage
DBS0351495	[cotB]: FLAG: fbxD	fbxD	delayed culmination
HW358	[cotB]: fpaB: myc	fpaB-1 | fpaB-2	decreased resistance to reduced oxygen levels
DBS0350705	[cotC]: pkaC	pkaC	precocious development | aberrant development | aberrant fruiting body morphology
DBS0350706	[cotC]: pkaC/ [spiA]: lacZ	pkaC | spiA	precocious gene expression
DBS0350048	[cycC]: cycC: TAP	cycC	decreased protein level
DBS0351493	[dscA]: His: agtA	agtA	decreased sporulation
DBS0351492	[dscA]: His: agtA(D132A)	agtA	aberrant stalk morphogenesis | abolished sporulation
DBS0305081	[dscB]: GFP: vamp7A(L35A)	vamp7A	increased localization to plasma membrane
DBS0351106	[dscB]: HA: racC	racC	decreased exocytosis | decreased pinocytosis | aberrant F-actin organization | decreased macropinocytosis | increased phagocytosis
DBS0350820	[dscB]: cafA	cafA	increased gene expression | precocious development
DBS0237237	[dscB]: cycB(106-436)	cycB	cell cycle arrest
DBS0350922	[dscB]: dicA(1-278)	dicA	increased cell death | abolished protein binding | aberrant microtubule cytoskeleton organization | aberrant Golgi localization | aberrant sister chromosome segregation | aberrant centrosome organization
DBS0350923	[dscB]: dicA(48-654)	dicA	aberrant microtubule cytoskeleton organization | aberrant Golgi localization | decreased protein binding | aberrant sister chromosome segregation | aberrant centrosome organization
DBS0351510	[dscB]: rac1B(G12V): myc	rac1B	decreased pinocytosis | aberrant F-actin organization | decreased growth rate | aberrant cytokinesis | delayed development | aberrant cell morphology
DBS0351511	[dscB]: rac1B(Q61L): myc	rac1B	aberrant F-actin organization | decreased growth rate | aberrant cytokinesis | delayed development | aberrant cell morphology
DBS0351512	[dscB]: rac1B(T17N): myc	rac1B	decreased pinocytosis | aberrant F-actin polymerization | decreased growth rate | aberrant cytokinesis | decreased chemotaxis to folate | delayed development | aberrant cell morphology
DBS0350589	[dscB]: rapA	rapA	decreased pinocytosis | aberrant F-actin organization | aberrant cell morphology | increased phagocytosis
DBS0350590	[dscB]: rapA(G12T)	rapA	decreased pinocytosis | increased phagocytosis
DBS0351227	[dscB]: rasG(G12T/ T45Q)	rasG	wild type | aberrant cell morphology
DBS0350933	[dscC]: kif2	kif2	aberrant cell cycle
DBS0351230	[ecmAO]: rasG(G12T)	rasG	mislocalized prestalk gene expression | aberrant culmination
DBS0350703	[ecmA]: pkaC	pkaC	abolished tip formation | development arrests at mound stage
DBS0350659	[ecmA]: pkaC(9-648)	pkaC	development arrests at tipped mound stage
DBS0350699	[ecmA]: pkaR(G135E/ G261A)	pkaR	decreased slug size | decreased gene expression | aberrant culminant morphology | delayed tip formation | aberrant slug migration | increased slug migration | aberrant prestalk cell differentiation
DBS0350700	[ecmA]: pkaR(G135E/ G261A)/ [ecmB-frag]: lacZ	pkaR	abolished stalk cell differentiation
DBS0350704	[ecmB]: pkaC	pkaC	abolished tip formation | development arrests at mound stage
DBS0350639	[ecmF]: expl3: myc	expl3	aberrant stalk morphogenesis | delayed slug formation
DBS0304865	[expl7]: expl7: GFP	expl7	aberrant culminant morphology
DBS0237252	[gpaA]: gpaA(G45V)	gpaA	delayed development
DBS0237253	[gpaA]: gpaA(Q206L)	gpaA	increased basal disc size
DBS0349948	[ndm]: ndm: RFP	ndm	development arrests at mound stage
DBS0236086	[pdsA-agg]: pdsA	pdsA	precocious development
DBS0236111	[pdsA-ldev]: pdsA	pdsA	development arrests at mound stage
DBS0236484	[pkaC]: pkaC	pkaC	increased gene expression | abolished SDF-2 production | decreased intracellular cAMP level | precocious development | precocious gene expression | aberrant fruiting body morphology
DBS0350709	[pkaC]: pkaC/ [dscC]: lacZ	dscC-1 | dscC-2 | pkaC	aberrant gene expression
DBS0350696	[pkaC]: pkaC/ srfA-	pkaC | srfA	aberrant spore coat morphology | aberrant gene expression
DBS0237289	[psmC1]: psmC1	psmC1	aberrant cytokinesis | delayed tip formation | delayed gene expression
DBS0350658	[pspA]: pkaC(9-648)	pkaC	precocious sporulation | aberrant fruiting body morphology
DBS0350697	[pspA]: pkaR(G135E/ G261A)	pkaR	abolished gene expression | decreased gene expression | aberrant sorus color
DBS0351229	[pspA]: rasG(G12T)	rasG	increased prestalk gene expression | decreased prespore gene expression | abolished phototaxis | increased prestalk cell differentiation | multiple tips in mound
DBS0237290	[ptpA1]: ptpA1	ptpA1-1 | ptpA1-2	delayed aggregation | decreased growth rate | aberrant fruiting body morphology
DBS0351231	[rasD]: rasG(G12T)	rasG	development arrests at loose mound stage | multiple tips in mound
DBS0236867	[rasG]: rasG(G12T)	rasG	aberrant aggregation
DBS0351461	[tet]rasD(G12T)	rasD	increased gene expression | increased prestalk cell differentiation
DBS0351463	[tet]rasD(G12T)/ rigA-	rasD | rigA	wild type
DBS0351290	[tre]: drkA: myc	drkA	decreased growth rate | increased protein tyrosine phosphorylation
DBS0304911	[tre]: paxB	paxB	abolished sporulation | aberrant endocytosis | decreased cell-substrate adhesion | aberrant chemotaxis to folate | development arrests at mound stage | decreased cell motility | increased cell-cell adhesion
DBS0350267	[tre]: secG	secG	increased filopodium formation | aberrant F-actin polymerization | development arrests at mound stage | aberrant actin cytoskeleton organization | abolished cell polarity | abolished chemotaxis to cAMP | delayed gene expression
DBS0351442	[unk]: GFP: RasG	rasG	increased macropinocytosis
DBS0351443	[unk]: GFP: RasG(G12T)	rasG	increased macropinocytosis
DBS0351444	[unk]: GFP: RasS	rasS	increased macropinocytosis
DBS0351445	[unk]: GFP: RasS(G12V)	rasS	increased macropinocytosis
DBS0350726	[unk]: GFP: cepE	cepE	increased number of centrosomes | aberrant cytokinesis
DBS0351454	[unk]: GFP: piaA(G963E)	piaA	delayed aggregation | decreased protein binding
DBS0351507	[unk]: GFP: wasA(I173A/ F179A)	wasA	abolished protein binding
DBS0350447	[unk]: PTEN(H385G/ N389A/ H390A)	pten	decreased localization to plasma membrane | decreased fruiting body size
DBS0351270	[unk]: gpgA(1-65)	gpgA	aberrant F-actin organization | abolished aggregation | aberrant localization to plasma membrane | abolished chemotaxis to cAMP
DBS0350716	[unk]: pdsA	pdsA	aberrant development
DBS0350259	[unk]: pikA(1-492(S7A/ S11A/ S109A/ S113A/ S177A/ S181A))	pikA	aberrant localization to plasma membrane
DBS0236859	[unk]: rasD(G12T)	rasD	increased intracellular myo-inositol level | decreased gene expression | increased prestalk gene expression | decreased prespore gene expression | development arrests at tipped mound stage | increased protein kinase activation
DBS0350837	[unk]: rasD(G12T)/ [rasD]: rapA	rapA | rasD	aberrant culmination | decreased prespore cell differentiation | aberrant gene expression | decreased stalk cell differentiation | multiple tips in mound
DBS0351430	[unk]: tps9(N236A)	tps9	decreased catalytic activity
DBS0350464	[unk]: vasP(1-197: 221-261: 285-380)	vasP	abolished F-actin polymerization
DBS0350463	[unk]: vasP(1-261: 285-380)	vasP	aberrant F-actin organization
DBS0350465	[unk]: vasP(1-340: 376-380)	vasP	decreased F-actin polymerization | aberrant F-actin organization
DBS0349920	aarA-/ [act15]: GFP-mhcA	aarA	aberrant stalk morphogenesis | aberrant protein localization
DBS0237938	abpC-/ [act15]: GFP: abpC(9-148)	abpC	aberrant phototaxis
DBS0235426	abpC-/ [act15]: abpC	abpC	wild type
DBS0350938	abpC-/ [act15]: abpC	abpC	wild type
DBS0237945	abpC-/ [act15]: abpC(1-348: 449-857): GFP	abpC	aberrant F-actin organization | aberrant phototaxis
DBS0237946	abpC-/ [act15]: abpC(1-556: 644-857): GFP	abpC	aberrant F-actin organization | aberrant phototaxis
DBS0237941	abpC-/ [act15]: abpC(1-739): GFP	abpC	aberrant phototaxis
DBS0349852	abpE-/ [act15]: abpE	abpE-1 | abpE-2	decreased phagocytosis
DBS0350720	acaA-/ [acaA-agg]: acaA: myc	acaA	wild type | decreased gene expression | decreased fruiting body size
DBS0350721	acaA-/ [acaA-psp]: acaA: myc	acaA	decreased gene expression | decreased aggregate size | decreased fruiting body size
DBS0350722	acaA-/ [acaA-pst]: acaA: myc	acaA	wild type
DBS0350702	acaA-/ [act15]: HA: pkaC	acaA | pkaC	wild type | delayed development | decreased intracellular cAMP level
DBS0350725	acaA-/ [act15]: HA: pkaC/ acrA-	acaA | acrA | pkaC	decreased gene expression | abolished adenylate cyclase activity | development arrests at tipped mound stage
DBS0350737	acaA-/ [act15]: acaA	acaA	aberrant slug formation
DBS0350738	acaA-/ [act15]: acaA(1-390;398-1407)	acaA	abolished aggregation
DBS0350739	acaA-/ [act15]: acaA(L394T/ K482N)	acaA	wild type
DBS0350735	acaA-/ [act15]: pkaR(G135E/ G261A)	acaA | pkaR	increased intracellular cAMP level
DBS0350736	acaA-/ [unk]: acaA(F306L/ S498G,K504E,E593V,I649T)	acaA	decreased gene expression | decreased intracellular cAMP level | abolished cAMP wave formation
DBS0350734	acaA-/ [unk]: acaA(N333D,G633S)	acaA	abolished adenylate cyclase activity
DBS0350733	acaA-/ [unk]: acaA(V427I,S642F)	acaA	abolished activation of adenylate cyclase
DBS0350711	acaA-/ [unk]: acgA	acaA | acgA	aberrant development
DBS0350055	acapA-/ [act15]: acapA(R633Q): GFP	acapA	aberrant filopodium formation | aberrant post-lysosome organization and biogenesis
DBS0350054	acapA-/ [act15]: acapA: GFP	acapA	increased filopodium formation
DBS0350723	acrA-/ [act15]: acaA(L394S)	acaA | acrA	wild type
DBS0237786	acrA-/ [act15]: acgA(1-401)	acgA | acrA	decreased gene expression | decreased prespore cell differentiation | decreased sporulation
DBS0350724	acrA-/ [pkaC]: pkaC	acrA | pkaC	decreased spore germination | decreased fruiting body size | precocious development | decreased sporulation
DBS0351190	adcC-/ [act15]: adcC(1-485)	adcC	decreased localization to plasma membrane
DBS0351189	adcC-/ [act15]: adcC(101-654): GFP	adcC	abolished localization to plasma membrane
DBS0235473	alrA-/ [act15]: alrA	alrA	wild type
DBS0235488	alxA-/ [act15]: FLAG: alxA	alxA	delayed development
DBS0235476	alxA-/ [act15]: alxA(1-596): myc2	alxA	wild type
DBS0235477	alxA-/ [act15]: alxA(1-697): myc2	alxA	wild type
DBS0235478	alxA-/ [act15]: alxA(155-697): myc2	alxA	aberrant fruiting body morphology
DBS0235479	alxA-/ [act15]: alxA(293-697): myc2	alxA	aberrant fruiting body morphology
DBS0235480	alxA-/ [act15]: alxA(460-794): myc2	alxA	aberrant fruiting body morphology
DBS0235481	alxA-/ [act15]: alxA(D310A/ N311A)	alxA	wild type
DBS0235482	alxA-/ [act15]: alxA(Q181E/ Q183)	alxA	wild type
DBS0235483	alxA-/ [act15]: alxA(S700A/ S704A/ S708A)	alxA	wild type
DBS0235484	alxA-/ [act15]: alxA(S700D/ S704D/ S708D)	alxA	wild type
DBS0235485	alxA-/ [act15]: alxA(Y315D)	alxA	wild type
DBS0235486	alxA-/ [act15]: alxA(Y315F)	alxA	wild type
DBS0235487	alxA-/ [act15]: alxA: myc2	alxA	wild type
DBS0349953	ampA/ [ampA]: TAP	ampA	increased protein secretion | development arrests at mound stage
DBS0235495	ampA/ [ampA]: ampA	ampA	increased pseudopod formation | decreased cell-substrate adhesion | increased pinocytosis | increased F-actin polymerization | aberrant chemotaxis to folate
DBS0349952	ampA/ [ampA]: ampA/ lmbd2B-	ampA | lmbd2B	aberrant chemotaxis
DBS0235501	amtC-/ [act15]: cudA	amtC | cudA	delayed culmination
DBS0235502	amtC-/ [ecmA]: cudA	amtC | cudA	delayed culmination
DBS0235503	amtC-/ [pspA]: cudA	amtC | cudA	development arrests at slug stage
DBS0305085	apm2-/ [dscB]: GFP: vamp7A	apm2 | vamp7A	increased protein localization to plasma membrane
DBS0305083	apm3-/ [dscB]: GFP: vamp7A	apm3 | vamp7A	increased protein localization to plasma membrane
DBS0235510	aprA-/ [act15]: aprA	aprA	decreased growth rate | aberrant fruiting body morphology
DBS0350009	aprA-/ [act15]: bzpN: GFP	aprA | bzpN	abolished negative regulation of vegetative growth
DBS0238085	atg1-/ [act15]: atg1	atg1	wild type
DBS0238092	atg1-/ [act15]: atg1(1-628)	atg1	aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238087	atg1-/ [act15]: atg1(K36A)	atg1	aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238089	atg1-/ [act15]: atg1(K36A/ 1-628)	atg1	aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0351477	atg7-/ [act15]: YFP: atg7(C563A)	atg7	aberrant sorus morphology | decreased spore germination | delayed development
DBS0351479	atg7-/ [act15]: pkaC: YFP	atg7 | pkaC	decreased prespore gene expression | decreased sporulation
DBS0305978	atg9-/ [act15]: GFP: atg9	atg9	wild type
DBS0305979	atg9-/ [act15]: atg9: GFP	atg9	wild type
DBS0351480	atg9-/ [act15]: pkaC: YFP	atg9 | pkaC	abolished sporulation
DBS0351266	carA-/ [act15]: gpbA: YFP	carA-1 | carA-2 | gpbA	abolished aggregation
DBS0350568	carA-/ carC-/ [act15]: carA(261-359;S299A,S302G,S303G,S304G,S308A,S324G,S325A,S331A)(369-392;S383A,S385A)	carA-1 | carA-2 | carC	aberrant F-actin polymerization | aberrant adaptation of adenylate cyclase | aberrant chemotaxis to cAMP | abolished streaming | aberrant cAMP wave formation
DBS0350436	cdk8-/ [act15]: myc: cdk8	cdk8	wild type
DBS0350437	cdk8-/ [act15]: myc: cdk8(D194A)	cdk8	decreased spore germination | abolished aggregation
DBS0306227	cenB-/ [act15]: RFP: cenB	cenB	wild type
DBS0350010	cfaD-/ [act15]: bzpN: GFP	bzpN | cfaD	abolished negative regulation of vegetative growth
DBS0302446	cfaD-/ [act15]: cfaD	cfaD	wild type
DBS0350090	chcA-/ [act15]: GFP: ap2a1	ap2a1-1 | ap2a1-2 | chcA	aberrant protein localization
DBS0302455	chcA-/ [act15]: epnA: GFP	chcA | epnA	aberrant protein localization to coated pits
DBS0350091	chcA-/ [act15]: gppA: GFP	chcA | gppA	aberrant protein localization to plasma membrane
DBS0235604	clc-/ [act15]: GFP-clc(146-194)	clc	abolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235605	clc-/ [act15]: GFP-clc(85-124)	clc	abolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235607	clc-/ [act15]GFP: clc(1-124)	clc	abolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0350474	cln3-/ [act15]: GFP: cln3	cln3	wild type
DBS0350309	cnrF-/ [act15]: cnrF: RFP	cnrF	wild type
DBS0302656	cnrN-/ [act15]: cnrN	cnrN	wild type
DBS0351521	corA-/ [act15]: FLAG: corA(1-432)	corA	abolished aggregation
DBS0350345	corA-/ [act15]: GFP: mhkA	corA | mhkA	wild type
DBS0350346	corA-/ [act15]: GFP: mhkB	corA | mhkB	wild type
DBS0350344	corA-/ [act15]: GFP: mhkC	corA | mhkC	decreased catalytic activity | wild type
DBS0350343	corA-/ [act15]: GFP: pakA(797-1197)	corA | pakA	wild type
DBS0350371	corA-/ [act15]: corA	corA	wild type
DBS0238320	cpnA-/ [act15]: GFP: cpnA	cpnA	delayed hypotonic response | decreased culmination | delayed development
DBS0349922	ctxA-/ [act15]: GFP-mhcA	ctxA	aberrant stalk morphogenesis | aberrant tip formation | aberrant protein localization
DBS0350293	ctxA-/ ctxB-/ [act15]: GFP: arcA	arcA | ctxA | ctxB	aberrant protein localization to cell cortex
DBS0349972	ctxA-/ ctxB-/ [act15]: acaA: YFP	acaA | ctxA | ctxB	aberrant fruiting body morphology
DBS0349973	ctxA-/ ctxB-/ [act15]: carA: YFP	carA-1 | carA-2 | ctxA | ctxB	abolished adenylate cyclase activity | abolished culmination | abolished streaming
DBS0266761	culB-/ [act15]: pkaC	culB | pkaC	abolished gene expression | abolished sporulation | precocious gene expression | abolished aggregation
DBS0349807	detA-/ [act6]: GFP: detA	detA	wild type
DBS0349816	detA-/ [act6]: GFP: detA/ [act6]: 3xHA: culD	culD | detA	increased gene expression
DBS0349817	detA-/ [act6]: GFP: detA/ [act6]: 3xHA: repE	detA | repE	increased gene expression
DBS0349813	detA-/ [cotB]: GFP	detA	decreased prespore cell differentiation
DBS0349811	detA-/ [ecm0]: lacZ	detA	aberrant prestalk 0 cell differentiation
DBS0349812	detA-/ [ecmA0]: GFP	detA	increased prestalk cell differentiation
DBS0349808	detA-/ [ecmA0]: lacZ	detA	increased prestalk cell differentiation
DBS0349809	detA-/ [ecmA]: lacZ	detA	increased prestalk A cell differentiation
DBS0349810	detA-/ [ecmB]: lacZ	detA	delayed development
DBS0350394	dgat1-/ dgat2-/ [act15]: GFP: dgat2	dgat1 | dgat2	wild type
DBS0235703	dhkA-/ [pkaC]: pkaC	dhkA | pkaC	aberrant stalk morphogenesis
DBS0235712	dhkK-/ [act15]: dhkK(D1125N)	dhkK	aberrant fruiting body morphology
DBS0235719	dia1-/ [act6]: trap1	dia1 | trap1	aberrant aggregation | decreased fruiting body size
DBS0235903	dimB-/ [act15]: dimA: GFP	dimA | dimB	abolished protein localization to nucleus
DBS0235904	dimB-/ [act15]: dimB: GFP	dimB	wild type
DBS0349975	dmtA-/ [dimB]: dimB	dimB | dmtA	decreased prestalk B cell differentiation
DBS0238511	drkC-/ [act15]: drkC(1-497): YFP	drkC	decreased phagocytosis
DBS0238513	drkC-/ [act15]: drkC(K518R): YFP	drkC	decreased phagocytosis
DBS0350218	drnB-/ [act15]: pre-miRNA	drnB	abolished microRNA processing
DBS0350210	drnB-/ [act6]: lacZ/ [RNAi]lacZ	drnB	abolished production of siRNA involved in RNA interference | abolished transitive RNA interference
DBS0302602	dsgg-/ OE]: dsgg(Delta-Fbox)	dsgg	wild type
DBS0302606	dsgg-/ [OE]: GFP: lvsD	dsgg | lvsD	wild type
DBS0302599	dsgg-/ [OE]: dsgg	dsgg	wild type
DBS0302601	dsgg-/ [OE]: dsgg(Q551A)	dsgg	aberrant contractile vacuole organization and biogenesis
DBS0302600	dsgg-/ [OE]: dsggR515A)	dsgg	aberrant contractile vacuole organization and biogenesis
DBS0302607	dsgg-/ [OE]: lvsA	dsgg | lvsA	aberrant contractile vacuole organization and biogenesis
DBS0302611	dsgg-/ [OE]: phgA	dsgg | phgA	aberrant contractile vacuole organization and biogenesis
DBS0302678	dsgg-/ [OE]: rab8A	dsgg | rab8A	aberrant contractile vacuole organization and biogenesis
DBS0238237	dstA-/ GFP: dstA(237-707): ORF+	dstA	abolished culmination | decreased stalk length
DBS0252824	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C	2C | dstA	aberrant fruiting body morphology
DBS0252823	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 7E	7E | dstA | hssB	wild type
DBS0252826	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165	DDB_G0276165 | dstA	aberrant fruiting body morphology
DBS0252825	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325	DDB_G0282325 | dstA	aberrant fruiting body morphology
DBS0252816	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssA	dstA | hssA	wild type
DBS0252822	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssB	dstA | hssB	wild type
DBS0350804	ehd-/ [act15]: dymA: GFP	dymA | ehd	aberrant phagosome maturation | decreased phagosomal proteolysis
DBS0302598	elmoA-/ [act15]: elmoA(1-903/ 959-977): GFP	elmoA	decreased cell motility | increased phagocytosis
DBS0302591	elmoA-/ [act15]: elmoA: GFP	elmoA	wild type
DBS0302457	epnA-/ [act15]: GFP: epnA(253-677)	epnA	aberrant spore morphology | abolished localization to coated pits | abolished localization to plasma membrane
DBS0302456	epnA-/ [act15]: epnA(1-133): GFP	epnA	aberrant localization to coated pits
DBS0302474	epnA-/ [act15]: epnA(R65A/ K78A): GFP	epnA	aberrant spore morphology | abolished localization to coated pits | abolished localization to plasma membrane | abolished phosphatidylinositol-4,5-bisphosphate binding | abolished protein localization to plasma membrane | abolished protein phosphorylation
DBS0302475	epnA-/ [act15]: epnA(T107A): GFP	epnA	aberrant spore morphology | abolished protein localization to plasma membrane
DBS0302454	epnA-/ [act15]: epnA: GFP	epnA	wild type
DBS0235948	eppA-/ [act6]: myc: eppA	eppA	wild type
DBS0350681	erkA-/ [act15]: gpaE	erkA | gpaE	wild type
DBS0304905	forC-/ [act15]: GFP: forC	forC	wild type
DBS0235971	forH-/ [act15]: GFP: forH	forH	increased filopodium formation | decreased cell motility | increased cell-substrate adhesion
DBS0304440	frmA-/ [unk]: GFP	frmA	decreased gene expression | increased cell-cell adhesion | delayed development | aberrant development | abolished phototaxis
DBS0305026	gabT-[pkaC]: pkaC	gabT | pkaC	aberrant protein secretion
DBS0304912	gbpC-/ [act15]: gbpC	gbpC	wild type
DBS0304917	gbpC-/ [act15]: gbpC(1-1698: 2005-2631)	gbpC	decreased chemotaxis to cAMP
DBS0349868	gbpC-/ [act15]: gbpC(1-2331: 2470-2631): GFP	gbpC	aberrant streaming | decreased chemotaxis to cAMP
DBS0304918	gbpC-/ [act15]: gbpC(311-2631)	gbpC	decreased chemotaxis to cAMP
DBS0304916	gbpC-/ [act15]: gbpC(F1892A)	gbpC	decreased chemotaxis to cAMP
DBS0304915	gbpC-/ [act15]: gbpC(F2082A/ E2084A/ F2564A/ E2566A)	gbpC	decreased chemotaxis to cAMP
DBS0304913	gbpC-/ [act15]: gbpC(K342N)	gbpC	decreased chemotaxis to cAMP
DBS0304914	gbpC-/ [act15]: gbpC(K905W)	gbpC	decreased chemotaxis to cAMP
DBS0235998	gbpD-/ [act15]: gbpD	gbpD	aberrant F-actin organization | increased cell-substrate adhesion | increased lateral pseudopod formation | decreased chemotaxis rate | abolished aggregation
DBS0350387	gcsA-/ [act15]: carA	carA-1 | carA-2 | gcsA	aberrant initiation of development
DBS0350388	gcsA-/ [act15]: yakA	gcsA | yakA	wild type
DBS0237190	gdt1-/ [act15]: pkaR(G135E/ G261A)	gdt1 | pkaR	increased gene expression | abolished aggregation
DBS0350449	gefA-/ dscB]: rasG(S17N)	gefA | rasG	decreased chemoattractant-mediated F-actin polymerization | decreased positive regulation of GTPase activity | aberrant chemotaxis to cAMP | decreased protein kinase activation
DBS0304985	gefQ-/ [act15]: GFP: gefQ(172-654)	gefQ	abolished Ras guanyl-nucleotide exchange factor activity | decreased phototaxis
DBS0304986	gefQ-/ [act15]: GFP: gefQ(910-1298)	gefQ	decreased phototaxis
DBS0238390	gnt15-/ [act15]: FLAG: gnt15	gnt15	wild type
DBS0238391	gnt15-/ [act15]: FLAG: gnt15	gnt15	wild type
DBS0236092	gpaA-/ [gpaA]: gpaA(G45V)	gpaA	delayed development
DBS0236093	gpaA-/ [gpaA]: gpaA(Q206L)	gpaA	increased basal disc size
JM1	gpaB-/ [OE]: carA	carA-1 | carA-2 | gpaB	decreased cAMP-induced Ca2+ influx
DBS0236096	gpaB-/ [act15]: gpaB	gpaB	abolished aggregation
DBS0266942	gpaB-/ [act15]: gpaB	gpaB	delayed aggregation
DBS0266939	gpaB-/ [act15]: gpaB(1-345): gpaD(337-345)	gpaB | gpaD	abolished aggregation
DBS0351103	gpaB-/ [act15]: gpaB(C4A)	gpaB	decreased cAMP-induced cGMP pulse | abolished localization to plasma membrane | abolished aggregation
DBS0237137	gpaB-/ [act15]: gpaB(D154V)	gpaB	aberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237138	gpaB-/ [act15]: gpaB(E190G)	gpaB	aberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased cAMP-induced cAMP pulse
DBS0351105	gpaB-/ [act15]: gpaB(G207A)	gpaB	abolished localization to plasma membrane
DBS0351104	gpaB-/ [act15]: gpaB(G2A)	gpaB	abolished localization to plasma membrane
DBS0237139	gpaB-/ [act15]: gpaB(I104S)	gpaB	aberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237140	gpaB-/ [act15]: gpaB(L110S)	gpaB	aberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237141	gpaB-/ [act15]: gpaB(L76P)	gpaB	abolished aggregation
DBS0237142	gpaB-/ [act15]: gpaB(N74D)	gpaB	decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | abolished aggregation | decreased cAMP-induced cAMP pulse
DBS0237143	gpaB-/ [act15]: gpaB(R64G)	gpaB	decreased chemotaxis rate | abolished aggregation
DBS0237144	gpaB-/ [act15]: gpaB(S155P)	gpaB	decreased chemotaxis rate | abolished aggregation
DBS0351217	gpaB-/ [act15]: gpaI	gpaB | gpaI	wild type
DBS0351214	gpaB-/ [act15]: rasG(S17N)	gpaB | rasG	abolished activation of GTPase activity
DBS0236097	gpaB-/ [gpaA]: gpaB	gpaB	abolished aggregation
DBS0236099	gpaB-/ [gpaB]: gpaB	gpaB	wild type
DBS0266944	gpaD-/ [act15]: gpaB	gpaB | gpaD	decreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266946	gpaD-/ [act15]: gpaB(1-345): gpaD(337-345)	gpaB | gpaD	decreased accumulation of cGMP | aberrant fruiting body morphology
DBS0266943	gpaD-/ [act15]: gpaD	gpaD	wild type
DBS0266945	gpaD-/ [act15]: gpaE	gpaD | gpaE	decreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266947	gpaD-/ [act15]: gpaE(1-339): gpaD(337-345)	gpaD | gpaE	decreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266941	gpaE-/ [act15]: gpaE	gpaE	precocious tip formation
DBS0266948	gpaE-/ [act15]: gpaE(1-339): gpaD(337-345)	gpaD | gpaE	precocious tip formation
DBS0350678	gpaE-/ [act15]: gpaE(K10E/ K11E)	gpaE	delayed tip formation | delayed gene expression
DBS0350470	gpbA-/ [act15]: GFP: cap	cap | gpbA	decreased phagocytosis
LW14	gpbA-/ [act15]: carA	carA-1 | carA-2 | gpbA	decreased cAMP-induced Ca2+ influx | decreased protein kinase activation | abolished aggregation
LW17	gpbA-/ [act15]: carC	carC | gpbA	abolished aggregation
DBS0351260	gpbA-/ [act15]: gpbA(A99T/ Y271H/ C335M)	gpbA	abolished activation of adenylate cyclase | aberrant fruiting body morphology
DBS0351261	gpbA-/ [act15]: gpbA(M30V/ K85R/ S104P/ Q163H)	gpbA	development arrests at mound stage | abolished activation of adenylate cyclase | decreased chemotaxis to cAMP
DBS0351263	gpbA-/ [act15]: gpbA(M48T/ I52T/ E310G)	gpbA	wild type | decreased gene expression | decreased activation of adenylate cyclase | aberrant slug formation
DBS0351259	gpbA-/ [act15]: gpbA(N147D/ H149R/ N237S)	gpbA	development arrests at mound stage | abolished activation of adenylate cyclase | abolished chemotaxis to cAMP
DBS0351264	gpbA-/ [act15]: gpbA(R13G/ N74S/ S79P/ H149R/ V178A/ V194R/ F293L)	gpbA	decreased gene expression | decreased activation of adenylate cyclase | development arrests at tipped mound stage
DBS0351262	gpbA-/ [act15]: gpbA(S196G/ V199D/ C211R)	gpbA	decreased activation of adenylate cyclase | aberrant fruiting body morphology
DBS0351258	gpbA-/ [act15]: gpbA(V88A/ F229S/ D235V)	gpbA	abolished activation of adenylate cyclase | decreased chemotaxis to cAMP | aberrant fruiting body morphology
HO547	gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: CFP: FKBP/ [act15]: limE(1-145): GFP	gpbA	aberrant cortical actin cytoskeleton organization
HO543	gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: YFP: FKBP	gpbA	abolished chemotaxis to folate | decreased electrotaxis
DBS0351198	gpbA-/ [act6]: yakA	gpbA | yakA	abolished growth
DBS0350479	gpr89-/ [act15]: gpr89: GFP	gpr89	wild type
DBS0304815	grlA-/ [act15]: grlA: GFP	grlA	aberrant tip formation
DBS0351147	grlH-/ [act15]: grlH	grlH	wild type
DBS0238866	grlJ-/ [act15]: grlJ: GFP	grlJ	wild type
DBS0350284	grlJ-/ [act15]: grlJ: GFP	grlJ	wild type
DBS0238687	grpA-/ [act15]: grpA-FLAG	grpA	wild type
DBS0349930	gskA-/ [act15]: GFP: tacA	gskA | tacA	increased protein localization to nucleus
DBS0349881	gskA-/ [act15]: gskA(Y214F)	gskA	abolished streaming
DBS0350260	gskA-/ [unk]: pikA(1-492(S7D/ S11D/ S109D/ S113D/ S177D/ S181D))	gskA | pikA	wild type
DBS0350348	gtaC-/ [act15]: GFP: gtaC	gtaC	wild type
DBS0350357	gtaC-/ [act15]: GFP: gtaC(C500,503,522,525S)	gtaC	aberrant gene expression | abolished aggregation | decreased fruiting body size
DBS0350358	gtaC-/ [act15]: GFP: gtaC(T376A/ S379,380A/ C500,503,522,525S)	gtaC	aberrant localization to nucleus
DBS0350361	gtaC-/ [act15]: gtaC: (468-496): GFP: gtaC	gtaC	development arrests at mound stage | decreased aggregate size | precocious development
DBS0350257	gxcC-/ [act15]: GFP: gxcC	gxcC	wild type
DBS0350269	gxcT-/ [act15]: GFP: gxcT	gxcT	wild type
DBS0350656	hatA-/ [hatB]: hatB	hatA | hatB	aberrant cellular response to stress
DBS0350289	hspc300-/ [act15]: myc: hspc300	hspc300	wild type
DBS0252702	icmA-/ [act15]: TAP: YFP: rasG	icmA-1 | icmA-2 | rasG	abolished C-terminal protein amino acid methylation
DBS0238521	icpA-/ [act15]: GFP: icpA(1-1013)	icpA	aberrant protein localization
DBS0350439	iplA-/ [act15]: GFP: iplA	iplA	wild type
DBS0351436	ireA-/ [act15]: ireA(K603N): GFP	ireA	decreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress
DBS0351437	ireA-/ [act15]: ireA(N927A): GFP	ireA	decreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress
DBS0350959	kif10-/ [act15]: dhcA(1384-4725)	dhcA | kif10	wild type
DBS0350022	kif5-/ [act15]: FLAG: kif5	kif5	aberrant cytokinesis | aberrant cell morphology
DBS0350023	kif5-/ [act15]: FLAG: kif5(342-990)	kif5	aberrant cell morphology
DBS0350024	kif5-/ [act15]: GFP: kif5(805-990)	kif5	aberrant cytokinesis
DBS0350947	kif8-/ [act15]: dhcA(1384-4725)	dhcA | kif8	wild type
DBS0350044	kil2-/ [act15]: kil1	kil1 | kil2	abolished defense response to bacterium
DBS0236493	krsA-/ [act15]: GFP: krsA	krsA	wild type
DBS0238721	krsA-/ [act15]: GFP: krsA	krsA	wild type
DBS0238722	krsA-/ [act15]: GFP: krsA(K49R)	krsA	aberrant streaming
DBS0238723	krsA-/ [act15]: GFP: krsA(T173A)	krsA	abolished streaming
DBS0238725	krsA-/ [act15]: GFP: krsA(deltaC)	krsA	aberrant streaming
DBS0238724	krsA-/ [act15]: GFP: krsA(deltaKinase)	krsA	abolished streaming
DBS0238726	krsA-/ [act15]: GFP: krsA(deltaNS)	krsA	abolished streaming
DBS0350537	ku80-/ myc: ku80(1-782)	ku80	decreased double-strand break repair via nonhomologous end joining
DBS0350453	lpten-/ [act15]: lpten: RFP	lpten	wild type
DBS0350036	mekA-/ [act15]: mekA(299-360)	mekA	decreased aggregate size
DBS0350035	mekA-/ [act15]: mekA(K321A)	mekA	decreased aggregate size
DBS0350032	mekA-/ [act15]: mekA(S444A/ T448A)	mekA	decreased aggregate size
DBS0238109	mekA-/ ppp4C-/ [act15]: FLAG: pppC	ppp4c	decreased aggregate size | precocious development
DBS0266674	mhcA-/ [act15]: GFP: abpC(9-148)	abpC | mhcA	decreased uropod retraction | decreased pseudopod retraction
DBS0266675	mhcA-/ [act15]: GFP: mhcA(E476K)	mhcA	decreased pseudopod retraction
DBS0350489	mhcA-/ [act15]: GFP: mhcA/ [RNAi]rmd1	mhcA | rmd1	aberrant protein localization
DBS0236548	mhcA-/ [act15]: GFP: pats1(2087-2351)	mhcA | pats1	aberrant cytokinesis
DBS0350291	mhcA-/ [act15]: gppA: GFP	gppA | mhcA	aberrant contractile vacuole morphology | decreased contractile vacuole discharge
DBS0236549	mhcA-/ [act15]: limE(1-145): GFP	limE | mhcA	increased F-actin polymerization
DBS0350808	mhcA-/ [act15]: mhcA(1-933: 1455-2116]	mhcA	wild type | aberrant cytokinesis | aberrant fruiting body morphology
DBS0238158	mhcA-/ [act15]: mhcA(81-2116)	mhcA	decreased growth rate | development arrests at tipped mound stage
DBS0236550	mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)	mhcA	decreased filopodium formation
DBS0236551	mhcA-/ [act15]: mhcA(T1823D/ T1833D/ T2029D)	mhcA	increased filopodium formation
DBS0350948	mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(E683K)	mhcA	aberrant catalytic activity
DBS0350949	mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R686C)	mhcA	aberrant catalytic activity
DBS0238157	mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R689H)	mhcA	decreased actin filament sliding
DBS0236557	mhkA-/ [act15]: mhkA	mhkA	decreased growth rate | development arrests at mound stage | aberrant cytokinesis | decreased myosin II assembly
DBS0351180	midA/ [act15]: midA(E200A)	midA	aberrant cellular homeostasis | decreased growth rate | decreased phototaxis
DBS0351182	midA/ [act15]: midA(G170V/ G172V)	midA	aberrant cellular homeostasis | decreased growth rate | decreased phototaxis
DBS0351181	midA/ [act15]: midA(N205A)	midA	aberrant cellular homeostasis | decreased growth rate | decreased phototaxis
DBS0238058	mlcE-/ [act15]: myc: mlcE	mlcE	wild type
DBS0349919	mlkA-/ [act15]: GFP-mhcA	mlkA	aberrant stalk morphogenesis
DBS0266904	mpl1-/ [act15]: flag: mpl1	mpl1	wild type
DBS0350391	mrfA-/ [act15]: myc: mrfA(K772A): FLAG	mrfA	aberrant protein modification
DBS0350390	mrfA-/ [act15]: myc: mrfA(S767A): FLAG	mrfA	aberrant protein modification | delayed development
DBS0350389	mrfA-/ [act15]: myc: mrfA: FLAG	mrfA	wild type
DBS0350990	myoA-/ myoB-/ [act15]: myoB	myoA | myoB	delayed aggregation
DBS0350991	myoA-/ myoB-/ [act15]: myoB(1-1057)	myoA | myoB	decreased pinocytosis | aberrant F-actin organization | decreased growth rate
DBS0350992	myoA-/ myoB-/ [act15]: myoB(S332)	myoA | myoB	decreased pinocytosis | aberrant F-actin organization | decreased growth rate
DBS0351378	myoB-/ [act15]: GFP: myoB(1-720)	myoB	abolished protein localization to plasma membrane
DBS0351379	myoB-/ [act15]: GFP: myoB(1-800,813-1111)	myoB	abolished protein localization to plasma membrane | abolished protein localization
DBS0351380	myoB-/ [act15]: GFP: myoB(713-1111)	myoB	abolished protein localization
DBS0351367	myoB-/ [act15]: myoB(S332A)	myoB	abolished protein phosphorylation
DBS0266889	myoI-/ [act15]: GFP: myoI	myoI	wild type
DBS0351400	myoI-/ [act15]: GFP: myoI(1-1020)	myoI	abolished localization to pseudopodium | decreased filopodium formation
DBS0351398	myoI-/ [act15]: GFP: myoI(2057-2357)	myoI	increased filopodium formation
DBS0266890	myoI-/ [act15]: GFP: myoI(809-1154)	myoI	decreased phagocytosis
DBS0351399	myoI-/ [act15]: GFP: myoI(K23333A,K2336A)	myoI	increased filopodium formation
DBS0237617	myoI-/ [act15]: gbpD	gbpD | myoI	increased pseudopod formation | increased cell-substrate adhesion | aberrant cell morphology
DBS0349846	myoK-/ [act15]: YFP: myoK(1-121: 262-858)	myoK	decreased phagocytosis
DBS0349850	myoK-/ [act15]: myoK	myoK	increased phagocytosis
DBS0349854	myoK-/ [act15]: pakB(1-337: 563-852)	myoK | pakB	wild type
DBS0349841	nhe1-/ [act15]: mhcA: GFP	mhcA | nhe1	aberrant protein localization
DBS0236611	noxA-/ [act15]: noxA: myc2	noxA	aberrant fruiting body morphology
DBS0350196	nsfA(A1854T, T1984A, C2131A, A2398T, T2574A)	nsfA | pkaC	abolished SDF production
DBS0236702	nxnA-/ [act15]: GFP: nxnB	nxnA | nxnB	development arrests at mound stage
DBS0238362	p2xA-/ [act15]: p2xA: GFP	p2xA	wild type
DBS0350014	pah-/ [act15]: 6xHis: pah	pah	wild type
DBS0350016	pah-/ [act15]: 6xHis: pah(92-415)	pah	abolished growth
DBS0350015	pah-/ [act15]: 6xHis: pah(92-441)	pah	wild type
DBS0350810	pakA-/ [act15]: pakA(T579A)	pakA	decreased chemotaxis to cAMP
DBS0349889	pakA-/ [act15]: pakA: GFP	pakA	wild type
DBS0350428	pakB-/ [act15]: RFP: abpE	abpE-1 | abpE-2 | pakB	aberrant establishment and/ or maintenance of cell polarity | decreased chemotaxis to cAMP | abolished aggregation | aberrant protein localization
DBS0350430	pakB-/ [act15]: RFP: abpE/ [act15]: GFP: pak(1-180)	abpE-1 | abpE-2 | pakB	wild type
DBS0350282	pakD-/ [act15]: pakD	pakD	development arrests at mound stage
DBS0350395	pakD-/ [act15]: pakD: GFP	pakD	wild type
DBS0350973	paxB-/ [act15]: gpaH	gpaH | paxB	aberrant cytokinesis
DBS0350094	paxB-/ [act15]: pldB	paxB | pldB	wild type | increased phagocytosis
DBS0350893	pdeD-/ pdeE-/ [unk]: pdeE	pdeD | pdeE	delayed aggregation
DBS0236747	pefB-/ noxA-/ [act15]: pefB	noxA | pefB	aberrant development
DBS0304869	phg1A-/ [act15]: phg1A(1-276): phg1B221-587)	phg1A | phg1B	decreased phagocytosis
DBS0304868	phg1A-/ [act15]: phg1B	phg1A | phg1B	increased secretion of lysosomal enzyme | wild type | decreased cell-substrate adhesion | aberrant protein level | decreased phagocytosis
DBS0304870	phg1A-/ [act15]: phg1B(1-220): phg1a(277-642)	phg1A | phg1B	decreased phagocytosis
DBS0237615	phg2-/ [act15]: gbpD	gbpD | phg2	increased pseudopod formation | aberrant cell morphology | abolished chemotaxis to cAMP
DBS0302610	phgA-/ [OE]: dsgg	dsgg | phgA	aberrant contractile vacuole organization and biogenesis
DBS0351455	piaA(G917D)/ [unk]: GFP: piaA(G963E)	piaA	abolished aggregation
DBS0350471	pikA-/ pikB-/ [act15]: GFP: cap	cap | pikA | pikB	wild type
DBS0351206	pirA-/ pirA(K193D/ R194D): EGFP	pirA	abolished protein localization
DBS0350708	pkaC-/ [act6]: pkaC(303-648)	pkaC	wild type
DBS0350707	pkaC-/ [act6]: pkaC(330-648)	pkaC	abolished aggregation
DBS0350919	pkcA-/ [act15]: pldB	pkcA | pldB	aberrant aggregation | decreased sporulation
DBS0267125	plc-/ [OE]: dagA(PH): GFP/ [OE]: plc	dagA | plc	increased CRAC localization to the plasma membrane | decreased chemotaxis to cAMP | aberrant protein localization
DBS0350047	plc-/ [act15]: pten: GFP	plc | pten	wild type | aberrant protein localization to cytoplasm
DBS0236797	pldB-/ [act15]: pldB: GFP	pldB	abolished aggregation
DBS0351356	ppk1-/ [act15]: GFP: hsp48	hsp48 | ppk1	decreased protein level
DBS0236825	ppk1-/ [act15]: ppk1	ppk1	wild type
DBS0238110	ppp4C-/ [act15]: smkA	ppp4c | smkA	development arrests at mound stage | delayed development
DBS0238034	proC-/ [unk]: FLAG: proC	proC	wild type
DBS0350305	psenA-/ psenB-/ [act15]: GFP: psenB	psenA | psenB	wild type
DBS0350306	psenA-/ psenB-/ [act15]: psenB(D348A/ D394A)	psenA | psenB	wild type
DBS0302356	psrA-/ [act15]: FLAG: gskA	gskA | psrA	increased protein kinase activation
DBS0302357	psrA-/ [act15]: gskA(K84M/ K85M)	gskA | psrA	decreased culmination | decreased gene expression | delayed development | increased protein kinase activation
DBS0350829	psrA-/ [unk]: FLAG: rasD(G12T)	psrA | rasD	increased protein kinase activation
DBS0350454	pten-/ [act15]: lpten: RFP	lpten | pten	wild type
DBS0349890	pten-/ [act15]: pakA: GFP	pakA | pten	aberrant cytokinesis
DBS0350754	pten-/ [act15]: pten(186-515): GFP	pten	decreased chemotaxis to cAMP | aberrant development
DBS0350755	pten-/ [act15]: pten(C124S): GFP	pten	decreased chemotaxis to cAMP | aberrant development
DBS0236831	pten-/ [act15]: pten: GFP	pten	wild type
DBS0349893	pten-/ pakA-/ [act15]: pakA(T585A): GFP	pakA | pten	decreased chemotaxis to cAMP
DBS0349900	pten-/ pakA-/ [act15]: pakA(T585E): GFP	pakA | pten	aberrant cytokinesis | decreased chemotaxis to cAMP
DBS0349899	pten-/ pakA-/ [act15]: pakA: GFP	pakA | pten	aberrant cytokinesis
DBS0350675	ptpB-/ [act15]: 6xHis: erkA	erkA | ptpB	aberrant streaming
DBS0350018	qdpr-/ [act15]: pah	pah | qdpr	decreased growth rate
DBS0350011	qkgA-/ [act15]: bzpN: GFP	bzpN | qkgA-1 | qkgA-2	abolished negative regulation of vegetative growth
DBS0237191	racC-/ [act15]: CFP: racC	racC	increased chemoattractant-mediated F-actin polymerization
DBS0351348	racE-/ [act15]: GFP: racE(G20V)	racE	decreased protein phosphorylation | decreased chemotaxis to cAMP
DBS0351349	racE-/ [act15]: GFP: racE(G23V)	racE	increased protein phosphorylation
DBS0351350	racE-/ [act15]: GFP: racE(S192D)	racE	increased protein phosphorylation
DBS0351347	racE-/ [act15]: GFP: racE(T25N)	racE	wild type
DBS0351351	racE-/ [act15]: GFP: rasC(Q62L)	racE | rasC	decreased protein phosphorylation
DBS0349949	racE-/ [act15]: fttB	fttB | racE	decreased growth rate
DBS0349946	racE-/ [act15]: fttB: GFP	fttB | racE	abolished protein localization to cell cortex
DBS0350956	racE-/ [act15]racE(G20V)	racE	wild type
DBS0350957	racE-/ [act15]racE(T25N)	racE	abolished cytokinesis
DBS0236844	racF2(G12V)	racF2	decreased cell-cell adhesion
DBS0236845	racF2(N17T)	racF2	increased cell-cell adhesion | decreased sexual fusion
DBS0350317	rapgap9-/ [act15]: GFP: rapgap9	rapgap9	wild type
DBS0237614	rasC-/ [act15]: gbpD	gbpD | rasC	increased cell-substrate adhesion | aberrant cell morphology
DBS0350740	rasC-/ [rasC]: rasG	rasC | rasG	abolished activation of adenylate cyclase | abolished aggregation
DBS0350742	rasC-/ [rasC]: rasG(1-77(D30A)): rasC(79-189)	rasC | rasG	wild type
DBS0350741	rasC-/ [rasC]: rasG(D30A)	rasC | rasG	aberrant aggregation | decreased activation of adenylate cyclase
DBS0266697	rasC-/ rasG-/ [act15]: carA	carA-1 | carA-2 | rasC | rasG	abolished growth | abolished activation of GTPase activity | decreased growth rate | decreased activation of adenylate cyclase | abolished protein kinase activation | abolished cAMP-induced cGMP pulse | abolished chemotaxis to cAMP
DBS0350480	rasC-/ rasG-/ [rasG]: rasD	rasC | rasD | rasG	decreased chemotaxis to folate
DBS0350482	rasC-/ rasG-/ [rasG]: rasD(1-104): rasG(103-189)	rasC | rasD | rasG	decreased chemotaxis to folate
DBS0350481	rasC-/ rasG-/ [rasG]: rasG	rasC | rasG	wild type
DBS0350483	rasC-/ rasG-/ [rasG]: rasG(1-104): rasD(103-187)	rasC | rasD | rasG	wild type
DBS0351062	rasC-/ rasG-/ [unk]: carA	carA-1 | carA-2 | rasC | rasG	decreased protein localization to plasma membrane
DBS0351213	rasC-[act15]: rasG(S17N)	rasC | rasG	abolished activation of GTPase activity | decreased chemotaxis to cAMP
DBS0236864	rasG-/ [OE]: rasB	rasB | rasG	decreased growth rate
DBS0350448	rasG-/ [dscB]: rasG(S17N)	rasG	decreased chemoattractant-mediated F-actin polymerization | decreased positive regulation of GTPase activity | decreased protein kinase activation | decreased chemotaxis to cAMP
DBS0349996	rblA-/ [act15]: GFP/ [act15]: myc: btg	btg | rblA	increased sorting to prestalk region
DBS0235706	regA-/ [act15]: dhkK(D1125N)	dhkK | regA	precocious development | aberrant fruiting body morphology
DBS0351475	regA-/ [act15]: erkA	erkA | regA	delayed slug formation
DBS0351472	regA-/ [act15]: regA(R588A,R589A,L594A,I595A,L596A)	regA	delayed development
DBS0351284	regA-/ [act15]: regA(S142A)	regA	precocious development | aberrant fruiting body morphology
DBS0351283	regA-/ [act15]: regA(S142E)	regA	delayed development
DBS0351285	regA-/ [act15]: regA(S413A)	regA	increased aggregate size | delayed development
DBS0351286	regA-/ [act15]: regA(S413E)	regA	increased aggregate size | delayed development
DBS0351287	regA-/ [act15]: regA(T676A)	regA	delayed sporulation
DBS0351288	regA-/ [act15]: regA(T676E)	regA	precocious development | aberrant fruiting body morphology
DBS0349921	rgaA-/ [act15]: GFP-mhcA	rgaA	aberrant stalk morphogenesis | aberrant tip formation | aberrant protein localization
DBS0350020	rgfA-/ [act15]: rgfA	rgfA	decreased chemotaxis to folate | delayed development
DBS0350193	ric8-/ [act15]: GFP: ric8	ric8	wild type
DBS0350219	rrpC-/ [act15]: pre-miRNA	rrpC	increased microRNA processing
DBS0350974	sadA-/ [act15]: gpaH	gpaH | sadA	aberrant cytokinesis
DBS0351524	scrA-/ [act15]: scrA(R177A,R179A,K180A,R183A,R184A,R187A,K190A,K191A,K194A)	scrA	increased cellular localization | decreased bleb formation | aberrant pseudopod formation
DBS0351522	scrA-/ [act15]: scrA(S430A,S432A,S433A,S437A,S440A)	scrA	increased cellular localization | decreased bleb formation | aberrant pseudopod formation
DBS0351523	scrA-/ [act15]: scrA(S430D,S432D,S433D,S437D,S440D)	scrA	decreased pseudopod size
DBS0349927	scrA-/ [act15]: wasA: GFP/ [ act8]: RFP: arcD	scrA	decreased cell polarity | decreased pseudopod formation
DBS0349957	sma-/ ampA/ [ampA]: ampA	ampA | sma	decreased chemotaxis to folate
DBS0351063	sodC-/ [unk]: rasG(C118A)	rasG | sodC	aberrant regulation of GTPase activity
DBS0350637	tagB-/ [pkaC]: pkaC	pkaC | tagB	abolished SDF-1 production | aberrant response to SDF-1
DBS0350698	tagC-/ [pkaC]: pkaC	pkaC | tagC	development arrests at mound stage | abolished SDF-2 production
DBS0236976	talA-	talA	decreased protein level | decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology
DBS0304585	talA-/ [act15]: FLAG: talB	talA | talB	decreased cell-substrate adhesion
DBS0237616	talA-/ [act15]: gbpD	gbpD | talA	increased pseudopod formation | increased cell-substrate adhesion | aberrant cell morphology
DBS0238395	talA-/ [act15]: rapA(G12V)	rapA | talA	increased cell-substrate adhesion
DBS0304582	talA-/ talB-/ [act15]: FLAG: talB	talA | talB	wild type
DBS0350713	talA-/ talB-/ [act15]: talB(K16A)	talA | talB	decreased cell-substrate adhesion
DBS0304586	talB-/ [act15]: talA: GFP	talA | talB	aberrant fruiting body morphology
DBS0350712	talB-/ [act15]: talB(K16A)	talB	development arrests at tipped mound stage
DBS0350729	tipC-/ [unk]: tipC(2725-3848): GFP	tipC	decreased fruiting body size
DBS0350505	tpp1-/ [cotB]: tpp1	tpp1	wild type
DBS0302383	tsuA-/ [unk]: tsuA(1-1774): YFP	tsuA	abolished localization to microtubules | decreased aggregate size | abolished localization to microtubule organizing center | decreased fruiting body size
DBS0302385	tsuA-/ [unk]: tsuA(1-260): YFP	tsuA	abolished localization to microtubules | abolished localization to microtubule organizing center | decreased aggregate size | decreased fruiting body size
DBS0302384	tsuA-/ [unk]: tsuA(1774-2247): YFP	tsuA	abolished localization to microtubules | abolished localization to microtubule organizing center | decreased aggregate size | decreased fruiting body size
DBS0302382	tsuA-/ [unk]: tsuA(K34R): YFP	tsuA	decreased aggregate size | decreased fruiting body size
DBS0237033	vasP-/ [act15]: GFP: vasP(1-264/ 285-380)	vasP	abolished filopodium formation
DBS0237836	vasP-/ [act15]: YFP: wipA	vasP | wipA	decreased filopodium formation
DBS0237842	vasP-/ [act15]: YFP: wipA/ [act15]: vasP: FLAG	vasP | wipA	increased filopodium formation
DBS0351313	vasP-/ [act15]: abpB(129-295)	abpB | vasP	aberrant cellular process
DBS0351300	vasP-/ [act15]: eYFP: vasP(S141A)	vasP	wild type | decreased cell polarity | aberrant F-actin organization | decreased localization to cell cortex | decreased lateral pseudopod suppression
DBS0351301	vasP-/ [act15]: eYFP: vasP(S141D)	vasP	aberrant hypertonic response | decreased filopodium formation
DBS0237040	vasP-/ [act15]: vasP	vasP	decreased filopodium formation
DBS0237840	vasP-/ [act15]: vasP	vasP	increased filopodium formation | increased basal F-actin level
DBS0237037	vasP-/ [act15]: vasP(1-110: 231-380)	vasP	increased basal F-actin level | aberrant cytokinesis | decreased filopodium formation
DBS0237038	vasP-/ [act15]: vasP(1-228)	vasP	decreased filopodium formation
DBS0237039	vasP-/ [act15]: vasP(111-380)	vasP	increased filopodium formation | increased basal F-actin level
DBS0350466	vasP-/ [unk]: vasP(1-197: 221-380)	vasP	wild type
DBS0350467	vasP-/ [unk]: vasP(1-261: 285-380)	vasP	decreased cell motility | abolished filopodium formation
DBS0350290	vwkA-/ [act15]: GFP: mhcA	mhcA | vwkA	aberrant myosin II organization
DBS0351509	wasA-/ [tet]: scrA/ [unk]: GFP: wasA(I173A/ F179A)	scrA | wasA	aberrant pseudopod formation
DBS0351508	wasA-/ [unk]: GFP: wasA(I173A/ F179A)	wasA	decreased cell polarity | aberrant protein localization
DBS0237812	wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA	wasA	increased F-actin polymerization at the leading edge
DBS0237811	wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA(Y33A/ W39A/ F90A/ F91A)	wasA	decreased F-actin polymerization | decreased F-actin polymerization at the leading edge
DBS0237820	wasA1-/ [tet]: YFP: wasA2/ [act15]: wipA	wasA | wipA	abolished positive chemotaxis
DBS0350255	wasB-/ [act15]: YFP: wasB	wasB	wild type
DBS0351185	washc5-/ [act15]: washc5(N457D): GFP	washc5	abolished exocytosis
DBS0350247	wshA-/ fam21-/ [act15]: GFP: wshA	fam21 | wshA	aberrant post-lysosome organization and biogenesis
DBS0350944	xacA-/ [act15]: xacA(1-320)	xacA	decreased growth rate | aberrant cytokinesis
DBS0350945	xacA-/ [act15]: xacA(779-1335)	xacA	decreased hypotonic response | aberrant contractile vacuole morphology
DBS0237091	yakA-/ [crlA]: crlA	crlA | yakA	abolished growth
DBS0349882	zak2-/ [ecmA]: zakA	zak2 | zakA	aberrant gene expression

Last updated June 28, 2020

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