To view more details, including parent strains and references, click on the corresponding dictyBase ID.
Systematic Name | Strain Descriptor | Associated gene(s) | Phenotypes |
---|---|---|---|
DBS0350657 | [csaA]: csaA | csaA | aberrant aggregation | increased calcium-independent cell-cell adhesion |
DBS0351382 | myoB-/ [act15]: GFP: myoB(1-921,1057-1111) | myoB | abolished protein localization to actin wave |
DBS0235594 | CHE10 | cbpC | decreased slug migration | precocious aggregation | decreased mound size | decreased fruiting body size | delayed culmination |
DBS0266719 | Dd5P4-/ [act15]: Dd5P4: GFP | Dd5P4 | wild type |
DBS0266695 | Dd5P4-/ [act15]: GAP5P4 | Dd5P4 | increased number of mound tips | decreased growth rate |
DBS0351414 | Dd5P4-/ [act15]: GFP: Dd5P4(D319G) | Dd5P4 | increased contractile vacuole size | aberrant contractile vacuole discharge | aberrant protein localization to contractile vacuole |
DBS0266720 | Dd5P4-/ [act15]: Hs-OCRL | Dd5P4 | decreased phagocytosis |
DBS0266721 | Dd5P4-/ [act15]: Hs-OCRL(D422A) | Dd5P4 | decreased phagocytosis |
DBS0266694 | Dd5P4-/ [act15]: cat5P4 | Dd5P4 | increased number of mound tips | decreased growth rate |
CW0391 | FLAG-VwkA | vwkA | increased myosin II assembly | decreased growth rate | aberrant cytokinesis | development arrests at mound stage | aberrant hypotonic response | increased protein level |
CW0368 | GFP-VwkA | vwkA | decreased growth rate | aberrant cytokinesis |
DBS0350102 | GFP: pcp | pcp | aberrant contractile vacuole morphology | aberrant hypotonic response |
DBS0351312 | HSPC300-/ [act15]: abpB(129-295) | abpB | hspc300 | aberrant cellular process |
DBS0237044 | VatMpr/ [act15]: vatM | vatM | wild type |
DBS0237042 | VatMpr/ [act15]: vatM: GFP | vatM | decreased growth rate |
DBS0351311 | [AS]proA/ abpB(129-295) | abpB | proA | aberrant cellular process |
DBS0238036 | [AS]proA/ proB-/ [act15]: proA | proA | proB | wild type |
DBS0238037 | [AS]proA/ proB-/ [act15]: proB | proA | proB | wild type |
DBS0238035 | [AS]proA/ proB-/ [unk]: FLAG: proC | proA | proB | proC | wild type |
DBS0237279 | [OE]: HA: rab21(Q66L) | rab21 | increased phagocytosis | aberrant cytoskeleton organization |
DBS0237274 | [OE]: chlim | ChLim | increased actin filament polymerization | decreased phagocytosis | decreased growth rate |
DBS0350519 | [OE]: egeA | egeA | decreased protein level | abolished aggregation |
DBS0237275 | [OE]: gbfA | gbfA | precocious prespore gene expression |
JH182 | [OE]: gpaD | gpaD | aberrant fruiting body morphogenesis | decreased sporulation |
JH258 | [OE]: gpaE | gpaE | precocious prestalk gene expression | precocious prespore gene expression | precocious development of tipped mound |
DBS0348921 | [OE]: ipkA1 | ipkA1 | aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression |
DBS0348922 | [OE]: itpk1 | itpk1 | aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression |
DBS0236962 | [OE]: pdiA | pdiA | delayed aggregation |
DBS0237015 | [OE]: pdiA | pdiA | aberrant development of tipped mound | abolished culmination | abolished slug development |
DBS0302681 | [OE]: sgcA(878-2843): GFP/ sgcA- | gcA | sgcA | aberrant chemotaxis to cAMP | decreased chemotaxis rate |
DBS0302682 | [OE]: sgcA(N1106A): GFP/ gca-/ sgcA- | gcA | sgcA | increased lateral pseudopodium formation | aberrant chemotaxis to cAMP | aberrant stream morphology | decreased chemotaxis rate |
DBS0266621 | [OE]mipp1 | mipp1 | aberrant inositol phosphate metabolic process | aberrant gene expression | increased response to lithium |
DBS0349923 | [RNAi]ctnnA/ [act15]: GFP-mhcA | ctnnA | aberrant stalk morphogenesis | decreased epithelium-like organization | aberrant protein localization |
DBS0350924 | [TRE-Pmin]: 6xHis: GFP: dhcA(1384-4725(K1975T)) | dhcA | aberrant molecular function |
DBS0350052 | [TRE-Pmin]: arfA(Q71L): GFP | arfA | aberrant filopodium formation | aberrant cytokinesis |
DBS0350053 | [TRE-Pmin]: arfA(T31N): GFP | arfA | wild type | increased defense response to Gram-negative bacterium |
DBS0351202 | [act15]: 6xHis: amd1: eYFP | amd1 | decreased gene expression | increased gene expression | aberrant vegetative growth | aberrant fruiting body morphogenesis | delayed development | mitotic G1 phase arrest |
DBS0351167 | [act15]: 6xHis: ei24: eYFP | ei24 | aberrant aggregation | increased chemotaxis to cAMP | aberrant cell cycle | increased cAMP level | increased sporulation |
DBS0350674 | [act15]: 6xHis: erkA | erkA | aberrant slug development |
DBS0351253 | [act15]: 6xHis: sesn: eYFP | sesn | aberrant aggregation | decreased protein level | increased gene expression | decreased growth rate | aberrant response to oxidative stress |
DBS0349845 | [act15]: 7xHis: myoK: Ty1 | myoK | aberrant cortical actin cytoskeleton organization | aberrant engulfment during phagocytosis | aberrant cell morphology |
DBS0237100 | [act15]: CFP: racC(G15V) | racC | increased actin filament polymerization |
DBS0266512 | [act15]: DDB_G0272656 | sigN4 | wild type |
DBS0350049 | [act15]: FLAG: cycC | cycC | precocious development of tipped mound |
DBS0350321 | [act15]: FLAG: hbx4 | hbx4 | aberrant aggregation | abolished gene expression | abolished slug migration | decreased growth rate | aberrant cytokinesis |
DBS0350322 | [act15]: FLAG: hbx4/ [act15]: cadA | cadA | hbx4 | wild type |
DBS0350325 | [act15]: FLAG: hbx4/ [ecmAO]: lacZ | hbx4 | decreased spore germination | increased prestalk gene expression | abolished prespore gene expression | increased prestalk cell differentiation |
DBS0351294 | [act15]: FLAG: mybB | mybB | increased gene expression | precocious development |
DBS0238107 | [act15]: FLAG: ppp4C | ppp4c | wild type |
DBS0238108 | [act15]: FLAG: ppp4C(H113Q) | ppp4c | development arrests at mound stage | delayed development |
DBS0351488 | [act15]: FLAG: rasC(Q62L) | rasC | abolished protein localization to plasma membrane | increased actin filament polymerization | decreased chemotaxis to cAMP |
DBS0351292 | [act15]: FLAG: sir2A | sir2A | delayed development |
DBS0351293 | [act15]: FLAG: sir2C | sir2C | delayed development |
DBS0351291 | [act15]: FLAG: sir2D | sir2D | increased gene expression | precocious development |
DBS0304572 | [act15]: GFP: abpD(1441-1736) | abpD | abolished protein localization to nuclear envelope |
DBS0304571 | [act15]: GFP: abpD(1441-1738) | abpD | abolished protein localization to nuclear envelope |
DBS0304573 | [act15]: GFP: abpD(1441-1738,1737P/ A) | abpD | abolished protein localization to nuclear envelope |
DBS0237114 | [act15]: GFP: abpE(413-481) | abpE-1 | abpE-2 | increased lateral pseudopodium formation |
DBS0351483 | [act15]: GFP: aqpB(1-208,219-294) | aqpB | decreased hypotonic response |
DBS0351097 | [act15]: GFP: cbpG | cbpG | increased cell-substrate adhesion | increased vegetative cell size | decreased chemotaxis to cAMP | abolished aggregation |
DBS0350593 | [act15]: GFP: cepL | cepL | decreased growth rate | decreased phagocytosis | increased vegetative cell size | increased cell-substrate adhesion | aberrant centrosome localization | decreased establishment of cell polarity |
DBS0350594 | [act15]: GFP: cepL(1-1114) | cepL | increased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis |
DBS0350595 | [act15]: GFP: cepL(1-763) | cepL | increased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis |
DBS0350596 | [act15]: GFP: cepL(763-1114) | cepL | development arrests at loose mound stage | abolished establishment of cell polarity | delayed aggregation | decreased vegetative cell size | increased cell-substrate adhesion | decreased chemotaxis rate | increased growth rate | aberrant phototaxis | delayed gene expression |
DBS0350460 | [act15]: GFP: docD | docD | increased actin filament polymerization | increased cell motility | increased pseudopodium formation |
DBS0350288 | [act15]: GFP: forF(1-1087) | forF | decreased pinocytosis | decreased phagocytosis | decreased growth rate |
DBS0235662 | [act15]: GFP: forH(1-425) | forH | abolished protein localization to pseudopodium |
DBS0350984 | [act15]: GFP: frmB | frmB | decreased spore size | aberrant stalk development |
DBS0304973 | [act15]: GFP: gefQ(173-651,818-1298) | gefQ | increased guanyl-nucleotide exchange factor activity |
DBS0304971 | [act15]: GFP: gefQ(683-833) | gefQ | decreased guanyl-nucleotide exchange factor activity |
DBS0304972 | [act15]: GFP: gefQ(910-1298) | gefQ | aberrant cytokinesis | aberrant phototaxis |
DBS0351254 | [act15]: GFP: gflB | gflB | decreased substrate adhesion-dependent cell spreading | decreased actin filament polymerization | increased cell motility |
DBS0350422 | [act15]: GFP: gpbB | gpbB | aberrant vegetative growth | delayed development |
DBS0350349 | [act15]: GFP: gtaC(1-467: 497-587) | gtaC | abolished protein localization to nucleus |
DBS0350351 | [act15]: GFP: gtaC(229-587) | gtaC | abolished protein localization to cytoplasm |
DBS0350359 | [act15]: GFP: gtaC(281-467: 497-587) | gtaC | aberrant protein localization to cytoplasm |
DBS0350352 | [act15]: GFP: gtaC(281-587) | gtaC | abolished protein localization to cytoplasm |
DBS0350360 | [act15]: GFP: gtaC(346-467: 497-587) | gtaC | aberrant protein localization to cytoplasm | aberrant protein localization to nucleus |
DBS0350353 | [act15]: GFP: gtaC(346-587) | gtaC | abolished protein localization to cytoplasm |
DBS0350350 | [act15]: GFP: gtaC(K469,470,494,496A/ R468,471A) | gtaC | abolished protein localization to nucleus |
DBS0236070 | [act15]: GFP: hcpA | hcpA | decreased growth rate | aberrant mitotic anaphase |
DBS0351562 | [act15]: GFP: impA1 | impa1 | decreased response to lithium |
DBS0237117 | [act15]: GFP: krsA | krsA | decreased slug migration |
DBS0237118 | [act15]: GFP: limE | limE | aberrant cytokinesis |
DBS0351530 | [act15]: GFP: lis1 | lis1 | decreased phagocytosis | decreased chemotaxis to folate |
DBS0349983 | [act15]: GFP: lmnB | lmnB | aberrant chromatin assembly |
DBS0350490 | [act15]: GFP: mhcA(T1823D/ T1833D/ T2029D)/ AX3 | mhcA | decreased growth rate | aberrant localization |
DBS0350852 | [act15]: GFP: nkaP | nkaP | aberrant aggregation | decreased gene expression | increased gene expression | aberrant vegetative growth | increased chemotaxis rate |
DBS0350338 | [act15]: GFP: pakA | pakA | increased phagocytosis |
DBS0350337 | [act15]: GFP: pakA(797-1197) | pakA | decreased phagocytosis | decreased cell motility |
DBS0237122 | [act15]: GFP: pats1(2087-2351) | pats1 | aberrant cytokinesis |
DBS0237123 | [act15]: GFP: phg2(1-245) | phg2 | decreased phagocytosis |
DBS0235442 | [act15]: GFP: pldB | pldB | abolished aggregation |
DBS0237702 | [act15]: GFP: rac1A | rac1A | increased filopodium formation | increased membrane ruffling | increased macropinocytosis | increased growth rate | increased cell motility |
DBS0351073 | [act15]: GFP: rac1A(G12V) | rac1A | decreased growth rate | decreased phagocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | delayed development | aberrant actin filament organization | abolished filopodium formation |
DBS0351075 | [act15]: GFP: rac1A(T17N) | rac1A | aberrant filopodium formation |
DBS0237703 | [act15]: GFP: rac1B | rac1B | increased filopodium formation | increased membrane ruffling |
DBS0237704 | [act15]: GFP: rac1C | rac1C | increased filopodium formation | increased membrane ruffling | increased growth rate | increased cell motility |
DBS0351074 | [act15]: GFP: rac1C(G12V) | rac1C | decreased growth rate | decreased phagocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | delayed development | aberrant actin filament organization | abolished filopodium formation |
DBS0351076 | [act15]: GFP: rac1C(T17N) | rac1C | aberrant filopodium formation |
DBS0237125 | [act15]: GFP: racG(1-168): racH(164-200) | racG | racH | increased filopodium formation | decreased actin filament polymerization | decreased phagocytosis |
DBS0237128 | [act15]: GFP: racH(1-163): racG(167-201) | racG | racH | decreased actin filament polymerization |
DBS0237130 | [act15]: GFP: racH(M13V) | racH | increased actin filament polymerization | aberrant cytokinesis | aberrant cell morphology |
DBS0237132 | [act15]: GFP: racH(T18N) | racH | aberrant cytokinesis | aberrant cell morphology |
DBS0237133 | [act15]: GFP: racH: gemA(630-658) | gemA | racH | delayed cytokinesis |
DBS0238392 | [act15]: GFP: rapA | rapA | increased cell-substrate adhesion |
DBS0238393 | [act15]: GFP: rapA(G12V) | rapA | increased cell-substrate adhesion |
DBS0238394 | [act15]: GFP: rapA(S17N) | rapA | decreased cell-substrate adhesion |
DBS0237134 | [act15]: GFP: sbds | sbds | wild type |
DBS0237135 | [act15]: GFP: sbds | sbds | wild type |
DBS0351177 | [act15]: GFP: sey1 | sey1 | decreased defense response to Gram-negative bacterium | aberrant vacuole organization |
DBS0350715 | [act15]: GFP: src1(2-646) | src1 | aberrant nuclear envelope morphology |
DBS0304563 | [act15]: GFP: sun1(283-905) | sun1 | increased number of centrosomes | decreased protein localization to nuclear envelope | aberrant nuclear membrane organization | aberrant nucleus morphology | increased vegetative cell size | aberrant centrosome localization | aberrant mitotic sister chromatid segregation |
DBS0350441 | [act15]: GFP: talA/ mhcA-/ talA- | mhcA | talA | aberrant protein localization |
DBS0350648 | [act15]: HA: Rab14(N121I) | rab14 | decreased pinocytosis | decreased hypotonic response | aberrant contractile vacuole morphology |
DBS0350899 | [act15]: HA: rab11(N126I) | rab11A | aberrant contractile vacuole organization | aberrant contractile vacuole morphology | increased phagocytosis |
DBS0350812 | [act15]: HA: rab7A(Q67L) | rab7A | increased exocytosis |
DBS0350813 | [act15]: HA: rab7A(T22N) | rab7A | decreased pinocytosis | increased secretion of lysosomal enzymes | decreased exocytosis | decreased phagocytosis | aberrant phagosome maturation | abolished macropinocytosis | abolished protein localization to phagocytic vesicle |
DBS0238111 | [act15]: HA: smkA | smkA | delayed development | decreased fruiting body size | decreased establishment of cell polarity | decreased chemotaxis to cAMP |
DBS0350429 | [act15]: RFP: abpE | abpE-1 | abpE-2 | delayed aggregation |
DBS0350867 | [act15]: RFP: mtpn | mtpn | increased filopodium formation | decreased protein localization to cell cortex | aberrant actin filament organization | decreased pseudopodium size |
DBS0351228 | [act15]: T7: rasG(G12T) | rasG | increased protein phosphorylation | decreased growth rate | decreased phagocytosis | increased cell-substrate adhesion | decreased filopodium formation |
DBS0351226 | [act15]: YFP: iqgC | iqgC | decreased phagocytosis | decreased macropinocytosis |
DBS0350986 | [act15]: YFP: myoC(G395A) | myoC | decreased pinocytosis | aberrant mitotic spindle organization | decreased phagocytosis |
DBS0237817 | [act15]: YFP: wipA | wipA | increased filopodium formation | increased actin filament polymerization at leading edge |
DBS0237819 | [act15]: YFP: wipA(K36A) | wipA | increased filopodium formation | increased actin filament polymerization at leading edge |
DBS0237821 | [act15]: YFP: wipA(K93A/ S95A) | wipA | increased filopodium formation | increased actin filament polymerization at leading edge |
DBS0350673 | [act15]: abpC: GFP | abpC | decreased cell motility |
DBS0304574 | [act15]: abpD | abpD | abolished protein localization to nuclear envelope |
DBS0237096 | [act15]: abpE | abpE-1 | abpE-2 | aberrant aggregation | increased lateral pseudopodium formation | decreased cell motility | delayed development | decreased fruiting body size |
DBS0350800 | [act15]: adprt1A | adprt1A | increased gene expression | decreased gene expression | decreased ATP level | delayed aggregation | aberrant cell cycle | decreased growth rate | aberrant response to oxidative stress | increased mitochondrial fission | decreased cAMP level |
DBS0238086 | [act15]: atg1 | atg1 | wild type |
DBS0238091 | [act15]: atg1(1-628) | atg1 | wild type |
DBS0238088 | [act15]: atg1(K36A) | atg1 | abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished aggregation |
DBS0238090 | [act15]: atg1(K36A/ 1-628) | atg1 | wild type |
DBS0350008 | [act15]: bzpN: GFP | bzpN | decreased growth rate | abolished negative regulation of vegetative growth |
JK1 | [act15]: carA | carA-1 | carA-2 | delayed aggregation |
DBS0252737 | [act15]: carA(I104A) | carA-1 | carA-2 | decreased cAMP binding |
DBS0252732 | [act15]: carA(I104C) | carA-1 | carA-2 | decreased protein kinase activation |
DBS0252740 | [act15]: carA(I104D) | carA-1 | carA-2 | increased cAMP binding | delayed aggregation | aberrant oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252744 | [act15]: carA(I104E) | carA-1 | carA-2 | increased cAMP binding | delayed aggregation | aberrant oscillatory cAMP signaling |
DBS0252741 | [act15]: carA(I104F) | carA-1 | carA-2 | increased cAMP binding | decreased protein kinase activation |
DBS0252738 | [act15]: carA(I104G) | carA-1 | carA-2 | increased cAMP binding | decreased protein kinase activation |
DBS0252747 | [act15]: carA(I104H) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252749 | [act15]: carA(I104K) | carA-1 | carA-2 | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation | abolished aggregation |
DBS0252739 | [act15]: carA(I104L) | carA-1 | carA-2 | wild type |
DBS0252742 | [act15]: carA(I104M) | carA-1 | carA-2 | increased cAMP binding |
DBS0252746 | [act15]: carA(I104N) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252734 | [act15]: carA(I104P) | carA-1 | carA-2 | decreased protein kinase activation |
DBS0252745 | [act15]: carA(I104Q) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252750 | [act15]: carA(I104R) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252743 | [act15]: carA(I104S) | carA-1 | carA-2 | increased cAMP binding | aberrant oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252735 | [act15]: carA(I104T) | carA-1 | carA-2 | increased cAMP binding | aberrant oscillatory cAMP signaling |
DBS0252736 | [act15]: carA(I104V) | carA-1 | carA-2 | wild type |
DBS0252733 | [act15]: carA(I104W) | carA-1 | carA-2 | increased cAMP binding |
DBS0252748 | [act15]: carA(I104Y) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | aberrant oscillatory cAMP signaling | decreased protein kinase activation |
DBS0351055 | [act15]: catA | catA | decreased slug migration | decreased fruiting body size | decreased superoxide generation | decreased sporulation |
DBS0351588 | [act15]: cdcD(E219K): RFP | cdcD | abolished catalytic activity |
DBS0302445 | [act15]: cfaD | cfaD | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0350333 | [act15]: cnrF: GFP | cnrF | aberrant regulation of GTPase activity |
DBS0302658 | [act15]: cnrN: myc/ smlA- | cnrN | smlA | decreased fruiting body size |
DBS0237102 | [act15]: cofA | cofA | increased actin bundle formation | increased membrane ruffling | increased cell motility |
DBS0350583 | [act15]: csaA | csaA | decreased cell-substrate adhesion | precocious aggregation | increased calcium-independent cell-cell adhesion |
DBS0349864 | [act15]: cyrA: GFP | cyrA | increased chemotaxis to cAMP |
DBS0237104 | [act15]: dagA | dagA | wild type |
DBS0350978 | [act15]: deeJ | deeJ | increased pinocytosis | increased growth rate | increased phagocytosis |
DBS0237106 | [act15]: dhkC(394-661) | dhkC | development arrests at slug stage | increased slug migration |
DBS0235716 | [act15]: dhkK | dhkK | precocious aggregation | development arrests at mound stage |
DBS0235705 | [act15]: dhkK(D1125N) | dhkK | aberrant extracellular cAMP signaling pathway | delayed development |
DBS0235707 | [act15]: dhkK(H825Q) | dhkK | precocious development | decreased fruiting body size |
DBS0235709 | [act15]: dhkK(H825Q/ D1125N) | dhkK | aberrant slug migration | delayed culmination |
DBS0351565 | [act15]: eIF6 | eIF6 | aberrant cellular process |
DBS0237108 | [act15]: fbxA: FLAG | fbxA | decreased prespore cell differentiation |
DBS0350365 | [act15]: fip(1163-2038) | fip-1 | fip-2 | aberrant prestalk O cell differentiation |
DBS0350012 | [act15]: fps: GFP | fps | increased resistance to alendronic acid |
DBS0235979 | [act15]: fszA: GFP | fszA | aberrant mitochondrion morphology |
DBS0351485 | [act15]: fszB: GFP | fszB | decreased mitochondrial fusion | decreased mitochondrial fission |
DBS0351056 | [act15]: gcsA | gcsA | increased catalytic activity | decreased slug migration | aberrant gene expression | decreased fruiting body size | decreased superoxide generation | decreased sporulation |
DBS0237136 | [act15]: gpaA | gpaA | increased stalk length | aberrant cytokinesis | aberrant fruiting body morphogenesis |
DBS0351058 | [act15]: gpaB | gpaB | aberrant aggregation | abolished sporulation | development arrests at mound stage | increased cAMP level | aberrant actin filament polymerization | decreased establishment of cell polarity | aberrant protein localization to plasma membrane | increased prestalk cell differentiation |
DBS0350680 | [act15]: gpaE | gpaE | abolished vegetative growth | decreased chemotaxis to folate |
DBS0237145 | [act15]: gpaG | gpaG | aberrant fruiting body morphogenesis |
DBS0237146 | [act15]: gpaH | gpaH | wild type |
DBS0350971 | [act15]: gpaH/ AX2 | gpaH | aberrant cytokinesis | decreased growth rate | aberrant spore germination | aberrant sorocarp development | increased cell-substrate adhesion | increased cell-cell adhesion |
DBS0350079 | [act15]: grlB | grlB | delayed aggregation |
DBS0351054 | [act15]: gshB | gshB | aberrant aggregation | abolished sporulation | increased gene expression | development arrests at mound stage | increased cAMP level | aberrant actin filament polymerization | decreased establishment of cell polarity |
DBS0351059 | [act15]: gshB/ [AS]gpaB | gpaB | gshB | aberrant stream morphology | decreased establishment of cell polarity | decreased sporulation |
DBS0350989 | [act15]: gst4 | gst4 | increased fruiting body size |
DBS0236152 | [act15]: hcpA(1-161: 218-225): GFP | hcpA | decreased growth rate |
DBS0252821 | [act15]: hssA | hssA | wild type |
DBS0351173 | [act15]: htrA(S300A) | htrA | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0351282 | [act15]: htt: eYFP | htt | decreased gene expression | increased gene expression |
DBS0350037 | [act15]: mekA(299-360) | mekA | decreased mound size |
DBS0350034 | [act15]: mekA(K321A) | mekA | decreased mound size |
DBS0350033 | [act15]: mekA(S444A/ T448A) | mekA | decreased mound size |
DBS0237203 | [act15]: mhkB: FLAG | mhkB | aberrant cytokinesis | decreased myosin II assembly |
DBS0350026 | [act15]: mip1/ [act15]: mekA: FLAG | mekA | mip1-1 | mip1-2 | aberrant protein localization to nucleus |
DBS0350331 | [act15]: mkpA: GFP: TAP | mkpA | increased resistance to cisplatin |
DBS0350330 | [act15]: mkpB: GFP: TAP | mkpB-1 | mkpB-2 | increased resistance to cisplatin |
DBS0237162 | [act15]: myc-cdk8 | cdk8 | increased number of tip-organizers | precocious development of tipped mound |
DBS0350050 | [act15]: myc: cdk8/ [act15]: FLAG: cycC | cdk8 | cycC | precocious development of tipped mound |
DBS0266837 | [act15]: myc: ptpC | ptpC | abolished protein localization to nucleus | aberrant hyperosmotic response | aberrant signal transduction |
DBS0350417 | [act15]: myc: ptpC | ptpC | aberrant protein phosphorylation |
DBS0266839 | [act15]: myc: ptpCΔ(C649S) | ptpC | aberrant protein localization to nucleus | increased protein tyrosine phosphorylation |
DBS0266838 | [act15]: myc: ptpC(C649S) | ptpC | aberrant protein localization to nucleus | increased protein tyrosine phosphorylation |
DBS0238398 | [act15]: myc: rapA | rapA | increased cell-substrate adhesion | decreased cell motility | aberrant cell morphology |
DBS0238396 | [act15]: myc: rapA(G12V) | rapA | increased protein localization to cell cortex | delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation |
DBS0238397 | [act15]: myc: rapA(S17N) | rapA | decreased cell-substrate adhesion |
DBS0237167 | [act15]: myc: rckA | rckA | delayed development |
DBS0237163 | [act15]: myc: rckA(C551A) | rckA | delayed slug development | decreased chemotaxis rate |
DBS0237164 | [act15]: myc: rckA(E510G) | rckA | delayed slug development | decreased chemotaxis rate |
DBS0237165 | [act15]: myc: rckA(E510G/ N511A) | rckA | delayed slug development | decreased chemotaxis rate |
DBS0237166 | [act15]: myc: rckA(K867A) | rckA | precocious aggregation | delayed slug development | decreased chemotaxis rate |
DBS0350132 | [act15]: myc: splB | splB | increased protein localization to nucleus | increased protein tyrosine phosphorylation |
DBS0351051 | [act15]: myc: talA(2255-2492)/ puf118(677-1036) | puf118 | talA | aberrant chemotaxis to cAMP | abolished protein localization to leading edge |
DBS0351359 | [act15]: myoB | myoB | decreased pinocytosis | increased protein localization to cell cortex | delayed aggregation | decreased growth rate | decreased cell motility | delayed development | decreased fruiting body size | aberrant actin filament organization |
DBS0351037 | [act15]: myoE(1-1005) | myoE | abolished phosphatidylinositol binding |
DBS0351036 | [act15]: myoE(K859A/ K863A/ R868A/ R869A): GFP | myoE | abolished phosphatidylinositol binding | abolished protein localization to plasma membrane |
DBS0349847 | [act15]: myoK: Myc | myoK | decreased phagocytosis |
DBS0237179 | [act15]: myr: rckA | rckA | delayed development | decreased chemotaxis rate |
DBS0349860 | [act15]: ndkC | ndkC-1 | ndkC-2 | decreased exocytosis | decreased pinocytosis | decreased phagocytosis | decreased growth rate | increased growth rate |
DBS0237180 | [act15]: nramp1: GFP | nramp1 | increased defense response to Gram-negative bacterium | increased iron ion transport |
DBS0350858 | [act15]: odc | odc | aberrant cellular metabolic process | aberrant cell cycle |
DBS0351201 | [act15]: odc: eYFP | odc | decreased growth rate | delayed development |
DBS0237182 | [act15]: pakA | pakA | wild type |
DBS0237183 | [act15]: pakA(K394A) | pakA | development arrests at mound stage | delayed development |
DBS0237184 | [act15]: pakA[CA] | pakA | abolished aggregation |
DBS0237185 | [act15]: pakA[G+K] | pakA | wild type |
DBS0351186 | [act15]: phr2ab: GFP | phr2aB | aberrant cytokinesis | aberrant centrosome organization |
DBS0349903 | [act15]: pisA | pisA | aberrant development of tipped mound | decreased slug migration | delayed aggregation | decreased fruiting body size |
DBS0349902 | [act15]: pisA: GFP | pisA | decreased slug migration | increased gene expression | decreased gene expression | delayed aggregation | delayed development | decreased phototaxis |
DBS0350693 | [act15]: pkaC | pkaC | precocious development |
DBS0237188 | [act15]: pkaC(1-497) | pkaC | precocious development | decreased fruiting body size | decreased cAMP level |
DBS0235418 | [act15]: pkaR | pkaR | aberrant response to abiotic stimulus |
DBS0237189 | [act15]: pkaR(G135E/ G261A) | pkaR | decreased protein tyrosine phosphorylation | decreased protein kinase activity | abolished cAMP binding | abolished oscillatory cAMP signaling | abolished aggregation |
DBS0350701 | [act15]: pkaR(G135E/ G261A)/ AX3 | pkaR | decreased gene expression | abolished oscillatory cAMP signaling |
DBS0350609 | [act15]: pkaR(S133T,G135E) | pkaR | decreased cAMP binding | decreased protein kinase activity | abolished oscillatory cAMP signaling | abolished aggregation |
DBS0350920 | [act15]: pkcA | pkcA | increased catalytic activity | abolished aggregation |
DBS0235538 | [act15]: pldB | pldB | increased catalytic activity | increased exocytosis | decreased actin filament polymerization | aberrant chemotaxis to cAMP | abolished aggregation | decreased sporulation |
DBS0349874 | [act15]: psaA: GFP | psaA | aberrant sporulation |
DBS0351577 | [act15]: psiA | psiA | decreased prespore gene expression | decreased stalk cell differentiation |
DBS0351579 | [act15]: psiA/ [cudA]: lacZ | psiA | aberrant prespore gene expression |
DBS0351580 | [act15]: psiA/ [ecmB]: lacZ | psiA | delayed prestalk gene expression |
DBS0350751 | [act15]: pten(16-515): GFP | pten | abolished catalytic activity |
DBS0350750 | [act15]: pten(186-515): GFP | pten | abolished catalytic activity |
DBS0350752 | [act15]: pten(C124S): GFP | pten | abolished catalytic activity |
DBS0350753 | [act15]: pten(G129E): GFP | pten | abolished catalytic activity |
DBS0350318 | [act15]: rab11A: RFP | rab11A | aberrant contractile vacuole organization | decreased contractile vacuole size | abolished hypotonic response |
DBS0350951 | [act15]: rac1B(Q61L) | rac1B | increased lateral pseudopodium formation | decreased chemotaxis to cAMP | aberrant actin filament organization |
DBS0350952 | [act15]: rac1B(T17N) | rac1B | abolished establishment of cell polarity | delayed aggregation | aberrant actin filament organization | abolished chemotaxis to cAMP |
DBS0350469 | [act15]: racE(G20V): GFP | racE | decreased actin filament polymerization | aberrant cytokinesis | decreased growth rate |
DBS0351497 | [act15]: rasD(Q61L) | rasD | decreased protein kinase activation |
DBS0351496 | [act15]: rasD(S17N) | rasD | increased protein kinase activation |
DBS0351212 | [act15]: rasG(S17N) | rasG | aberrant activation of GTPase activity | decreased chemotaxis to cAMP |
DBS0350262 | [act15]: rbg3 | rbg3 | increased lysosome size | decreased growth rate | delayed development |
DBS0237192 | [act15]: rblA | rblA | delayed mitotic cell cycle |
DBS0349938 | [act15]: rgaA | rgaA | decreased actin filament polymerization | aberrant cytokinesis | decreased cell motility |
DBS0351529 | [act15]: rgbA(751-1072,1080-1284,1517-1846) | rgbA | aberrant macropinocytosis | abolished protein localization to macropinosome |
DBS0351528 | [act15]: rgbA(751-1072,1121-1317,1505-1834) | rgbA | aberrant macropinocytosis | abolished protein localization to macropinosome |
DBS0351304 | [act15]: rheb | rheb | decreased phagocytosis | decreased macropinocytosis | increased growth rate |
DBS0350294 | [act15]: rheb: YFP | rheb | increased vegetative cell size |
DBS0350890 | [act15]: rnp1A | rnp1A | increased resistance to nocodazole |
DBS0350575 | [act15]: rps4 | rps4 | decreased spore germination | aberrant actin cytoskeleton organization | aberrant vegetative growth | decreased mound size | decreased spore size | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0236915 | [act15]: rzpA | rzpA | increased prestalk gene expression | decreased prespore gene expression | delayed culmination |
DBS0349793 | [act15]: sadA(921-952) | sadA | decreased cell-substrate adhesion |
SA604 | [act15]: sgkA: FLAG | sgkA | aberrant response to abiotic stimulus | increased resistance to cisplatin | aberrant cytokinesis | increased resistance to carboplatin |
HPF437 | [act15]: snfA(1-379): GFP | snfA | increased stalk width | increased ATP level | decreased growth rate | increased number of mitochondria | decreased defense response to bacterium | decreased phototaxis | decreased stalk length | aberrant mitochondrion organization |
DBS0351040 | [act15]: snfA(1-379): GFP/ [AS]ndkC-1 | ndkC-1 | ndkC-2 | snfA | wild type |
DBS0350976 | [act15]: snfA: YFP | snfA | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0351053 | [act15]: sod2 | sod2 | decreased slug migration | decreased fruiting body size | decreased superoxide generation | decreased sporulation |
DBS0304457 | [act15]: sodA/ gcsA- | gcsA | sodA | wild type |
DBS0237194 | [act15]: sodA: myc | sodA | aberrant response to abiotic stimulus | decreased gene expression | abolished aggregation |
DBS0237195 | [act15]: spkA: FLAG | spkA-1 | spkA-2 | aberrant aggregation | decreased chemotaxis rate | aberrant actin filament organization | decreased establishment of cell polarity |
AK1209 | [act15]: tagA(1-890) | tagA | increased number of mound tips |
DBS0350962 | [act15]: tor(212-2380): YFP | tor | decreased growth rate | aberrant sorocarp development |
DBS0237198 | [act15]: torA | torA | abolished vegetative growth |
DBS0350862 | [act15]: tpt1: YFP | tpt1 | decreased gene expression | decreased growth rate | decreased number of mounds | delayed development | aberrant fruiting body morphogenesis |
DBS0237199 | [act15]: trrA | trrA | aberrant aggregation | decreased growth rate | decreased phagocytosis | delayed culmination |
DBS0351572 | [act15]: vacA: GFP | vacA | decreased phagocytosis |
DBS0351573 | [act15]: vacB: GFP | vacB | decreased phagocytosis |
DBS0351574 | [act15]: vacC: GFP | vacC | decreased phagocytosis |
DBS0237200 | [act15]: vasP | vasP | increased filopodium formation | increased actin filament polymerization |
DBS0351184 | [act15]: washc5(N457D): GFP | washc5 | aberrant cytokinesis |
DBS0351183 | [act15]: washc5: GFP | washc5 | aberrant cytokinesis |
DBS0350911 | [act6]: GFP: cepA/ cepA(183-346) | cepA | increased number of centrosomes |
DBS0351235 | [act6]: GFP: cepL | cepL | increased number of microtubule organizing center |
DBS0351586 | [act6]: GFP: gefQ(S431A) | gefQ | increased number of mound tips | delayed development |
DBS0349984 | [act6]: GFP: lmnB(1-712) | lmnB | aberrant cellular response to fluid shear stress | aberrant intermediate filament organization | abolished vegetative growth |
DBS0350497 | [act6]: GFP: rab2A | rab2A | decreased pinocytosis | decreased phagocytosis | aberrant hypotonic response | increased growth rate |
DBS0350499 | [act6]: GFP: rab2A(Q64L) | rab2A | decreased autophagic cell death | aberrant cell-cell adhesion | aberrant sorocarp development | aberrant hypotonic response | increased growth rate | increased phagocytosis |
DBS0306243 | [act6]: GFP: sun1 | sun1 | increased number of centrosomes | aberrant nucleus morphology | aberrant mitotic sister chromatid segregation | aberrant centromere complex assembly | aberrant centrosome organization |
DBS0306244 | [act6]: GFP: sun1(1-722) | sun1 | increased number of centrosomes | aberrant nucleus morphology | aberrant mitotic sister chromatid segregation | aberrant centromere complex assembly | aberrant centrosome organization |
DBS0350685 | [act6]: csaA | csaA | increased migratory slug size | increased calcium-independent cell-cell adhesion |
DBS0237205 | [act6]: dia1 | dia1 | delayed aggregation |
DBS0236905 | [act6]: mrps4 | mrps4 | precocious aggregation |
DBS0235444 | [act6]: myc: eppA(S250A) | eppA | decreased growth rate | delayed development | decreased cAMP level |
DBS0235445 | [act6]: myc: eppA(S325A) | eppA | decreased growth rate |
DBS0266836 | [act6]: ptpB | ptpB | delayed aggregation | decreased fruiting body size |
DBS0350807 | [act6]: rabS(N137I): GFP | rabS | increased secretion of lysosomal enzymes | aberrant contractile vacuole organization | increased endocytic recycling |
DBS0350806 | [act6]: rabS: GFP | rabS | decreased cell-cell adhesion | increased secretion of lysosomal enzymes | increased cell death | increased pinocytosis | aberrant sorocarp development | aberrant hyperosmotic response | decreased chemotaxis to cAMP | increased growth rate | increased phagocytosis |
DBS0350982 | [act6]: rps6 | rps6 | aberrant cytokinesis | delayed development |
DBS0304410 | [act6]: srsA | srsA | increased migratory slug size | increased mound size | decreased gene expression | delayed aggregation | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0237220 | [act6]: trap1 | trap1 | development arrests at loose mound stage | aberrant aggregation | abolished pinocytosis | increased gene expression | decreased gene expression | decreased growth rate |
DBS0350695 | [act6]: yakA | yakA | increased gene expression | abolished vegetative growth |
DBS0350069 | [act6]: zizB: GFP | zizB | aberrant cell separation during cytokinesis | increased filopodium formation |
DBS0304460 | [act]: alrA/ gcsA- | alrA | gcsA | wild type |
DBS0349955 | [ampA]: RFP: ampA | ampA | development arrests at mound stage |
DBS0351495 | [cotB]: FLAG: fbxD | fbxD | delayed culmination |
HW358 | [cotB]: fpaB: myc | fpaB-1 | fpaB-2 | increased response to hypoxia |
DBS0350705 | [cotC]: pkaC | pkaC | aberrant sorocarp development | aberrant fruiting body morphogenesis | precocious development |
DBS0350706 | [cotC]: pkaC/ [spiA]: lacZ | pkaC | spiA | precocious gene expression |
DBS0350048 | [cycC]: cycC: TAP | cycC | decreased protein level |
DBS0351493 | [dscA]: His: agtA | agtA | decreased sporulation |
DBS0351492 | [dscA]: His: agtA(D132A) | agtA | aberrant stalk morphogenesis | abolished sporulation |
DBS0305081 | [dscB]: GFP: vamp7A(L35A) | vamp7A | increased protein localization to plasma membrane |
DBS0351106 | [dscB]: HA: racC | racC | decreased exocytosis | decreased pinocytosis | decreased macropinocytosis | aberrant actin filament organization | increased phagocytosis |
DBS0350820 | [dscB]: cafA | cafA | increased gene expression | precocious development |
DBS0237237 | [dscB]: cycB(106-436) | cycB | mitotic M phase arrest |
DBS0350922 | [dscB]: dicA(1-278) | dicA | increased cell death | abolished protein binding | aberrant microtubule cytoskeleton organization | aberrant Golgi localization | aberrant mitotic sister chromatid segregation | aberrant centrosome organization |
DBS0350923 | [dscB]: dicA(48-654) | dicA | aberrant microtubule cytoskeleton organization | aberrant Golgi localization | decreased protein binding | aberrant mitotic sister chromatid segregation | aberrant centrosome organization |
DBS0351510 | [dscB]: rac1B(G12V): myc | rac1B | decreased pinocytosis | decreased growth rate | aberrant cytokinesis | delayed development | aberrant actin filament organization | aberrant cell morphology |
DBS0351511 | [dscB]: rac1B(Q61L): myc | rac1B | decreased growth rate | aberrant cytokinesis | delayed development | aberrant actin filament organization | aberrant cell morphology |
DBS0351512 | [dscB]: rac1B(T17N): myc | rac1B | decreased pinocytosis | decreased growth rate | aberrant cytokinesis | decreased chemotaxis to folate | delayed development | aberrant actin filament polymerization | aberrant cell morphology |
DBS0350589 | [dscB]: rapA | rapA | decreased pinocytosis | aberrant actin filament organization | aberrant cell morphology | increased phagocytosis |
DBS0350590 | [dscB]: rapA(G12T) | rapA | decreased pinocytosis | increased phagocytosis |
DBS0351227 | [dscB]: rasG(G12T/ T45Q) | rasG | wild type | aberrant cell morphology |
DBS0350933 | [dscC]: kif2 | kif2 | aberrant cell cycle |
DBS0351230 | [ecmAO]: rasG(G12T) | rasG | aberrant prestalk gene expression | aberrant culmination |
DBS0350703 | [ecmA]: pkaC | pkaC | development arrests at mound stage | abolished development of tipped mound |
DBS0350659 | [ecmA]: pkaC(9-648) | pkaC | development arrests at tipped mound stage |
DBS0350699 | [ecmA]: pkaR(G135E/ G261A) | pkaR | decreased migratory slug size | delayed development of tipped mound | aberrant culmination | aberrant slug migration | decreased prestalk gene expression | increased slug migration | aberrant prestalk cell differentiation |
DBS0350700 | [ecmA]: pkaR(G135E/ G261A)/ [ecmB-frag]: lacZ | pkaR | abolished stalk cell differentiation |
DBS0350704 | [ecmB]: pkaC | pkaC | development arrests at mound stage | abolished development of tipped mound |
DBS0350639 | [ecmF]: expl3: myc | expl3 | aberrant stalk morphogenesis | delayed slug development |
DBS0304865 | [expl7]: expl7: GFP | expl7 | aberrant late culminant morphology |
DBS0237252 | [gpaA]: gpaA(G45V) | gpaA | delayed development |
DBS0237253 | [gpaA]: gpaA(Q206L) | gpaA | increased basal disc size |
DBS0349948 | [ndm]: ndm: RFP | ndm | development arrests at mound stage |
DBS0236086 | [pdsA-agg]: pdsA | pdsA | precocious development |
DBS0236111 | [pdsA-ldev]: pdsA | pdsA | development arrests at mound stage |
DBS0236484 | [pkaC]: pkaC | pkaC | increased gene expression | precocious prespore gene expression | decreased spore cell differentiation | aberrant fruiting body morphogenesis | precocious development | precocious gene expression | decreased cAMP level |
DBS0350709 | [pkaC]: pkaC/ [dscC]: lacZ | dscC-1 | dscC-2 | pkaC | aberrant gene expression |
DBS0350196 | [pkaC]: pkaC/ nsfA(A1854T,T1984A,C2131A,A2398T,T2574A) | nsfA | pkaC | decreased spore cell differentiation |
DBS0350696 | [pkaC]: pkaC/ srfA- | pkaC | srfA | aberrant spore coat morphology | aberrant gene expression |
DBS0237289 | [psmC1]: psmC1 | psmC1 | delayed development of tipped mound | aberrant cytokinesis | delayed gene expression |
DBS0350658 | [pspA]: pkaC(9-648) | pkaC | precocious sporulation | aberrant fruiting body morphogenesis |
DBS0350697 | [pspA]: pkaR(G135E/ G261A) | pkaR | abolished gene expression | decreased prespore gene expression | aberrant sorus color |
DBS0351229 | [pspA]: rasG(G12T) | rasG | increased number of mound tips | increased prestalk gene expression | decreased prespore gene expression | abolished phototaxis | increased prestalk cell differentiation |
DBS0237290 | [ptpA1]: ptpA1 | ptpA1-1 | ptpA1-2 | delayed aggregation | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0351231 | [rasD]: rasG(G12T) | rasG | development arrests at loose mound stage | increased number of mound tips |
DBS0236867 | [rasG]: rasG(G12T) | rasG | aberrant aggregation |
SA601 | [sglA-myc]neoR-1 | sglA | decreased resistance to carboplatin | decreased growth rate | aberrant cytokinesis | decreased resistance to cisplatin |
DBS0351461 | [tet]rasD(G12T) | rasD | increased gene expression | increased prestalk cell differentiation |
DBS0351463 | [tet]rasD(G12T)/ rigA- | rasD | rigA | wild type |
DBS0351290 | [tre]: drkA: myc | drkA | decreased growth rate | increased protein tyrosine phosphorylation |
DBS0304911 | [tre]: paxB | paxB | abolished sporulation | aberrant endocytosis | decreased cell-substrate adhesion | aberrant chemotaxis to folate | development arrests at mound stage | decreased cell motility | increased cell-cell adhesion |
DBS0350267 | [tre]: secG | secG | increased filopodium formation | abolished establishment of cell polarity | development arrests at mound stage | aberrant actin cytoskeleton organization | aberrant actin filament polymerization | abolished chemotaxis to cAMP | delayed gene expression |
DBS0351555 | [unk]: FLAG: rab1A(Q67L) | rab1A | aberrant actin filament polymerization | aberrant pseudopodium formation |
DBS0351556 | [unk]: FLAG: rab1A(S22N) | rab1A | decreased actin filament polymerization | decreased chemotaxis to cAMP |
DBS0351442 | [unk]: GFP: RasG | rasG | increased macropinocytosis |
DBS0351443 | [unk]: GFP: RasG(G12T) | rasG | increased macropinocytosis |
DBS0351444 | [unk]: GFP: RasS | rasS | increased macropinocytosis |
DBS0351445 | [unk]: GFP: RasS(G12V) | rasS | increased macropinocytosis |
DBS0350726 | [unk]: GFP: cepE | cepE | increased number of centrosomes | aberrant cytokinesis |
DBS0351454 | [unk]: GFP: piaA(G963E) | piaA | delayed aggregation | decreased protein binding |
DBS0351507 | [unk]: GFP: wasA(I173A/ F179A) | wasA | abolished protein binding |
DBS0350447 | [unk]: PTEN(H385G/ N389A/ H390A) | pten | decreased protein localization to plasma membrane | decreased fruiting body size |
DBS0351270 | [unk]: gpgA(1-65) | gpgA | decreased protein localization to plasma membrane | abolished aggregation | aberrant actin filament organization | abolished chemotaxis to cAMP |
DBS0350716 | [unk]: pdsA | pdsA | aberrant sorocarp development |
DBS0350259 | [unk]: pikA(1-492(S7A/ S11A/ S109A/ S113A/ S177A/ S181A)) | pikA | increased protein localization to plasma membrane |
DBS0236859 | [unk]: rasD(G12T) | rasD | increased myo-inositol level | decreased gene expression | increased prestalk gene expression | decreased prespore gene expression | development arrests at tipped mound stage | increased protein kinase activation |
DBS0350837 | [unk]: rasD(G12T)/ [rasD]: rapA | rapA | rasD | increased number of mound tips | aberrant culmination | decreased prespore cell differentiation | aberrant gene expression | decreased stalk cell differentiation |
DBS0351430 | [unk]: tps9(N236A) | tps9 | decreased catalytic activity |
DBS0351561 | [unk]: vacA: myc: vasP | vacA | vasP | decreased phagocytosis | decreased growth rate | aberrant cytokinesis | increased protein level | aberrant cell morphology |
DBS0350464 | [unk]: vasP(1-197: 221-261: 285-380) | vasP | abolished actin filament polymerization |
DBS0350463 | [unk]: vasP(1-261: 285-380) | vasP | aberrant actin filament organization |
DBS0350465 | [unk]: vasP(1-340: 376-380) | vasP | decreased actin filament polymerization | aberrant actin filament organization |
DBS0349920 | aarA-/ [act15]: GFP-mhcA | aarA | aberrant stalk morphogenesis | aberrant protein localization |
DBS0237938 | abpC-/ [act15]: GFP: abpC(9-148) | abpC | aberrant phototaxis |
DBS0235426 | abpC-/ [act15]: abpC | abpC | wild type |
DBS0350938 | abpC-/ [act15]: abpC | abpC | wild type |
DBS0237945 | abpC-/ [act15]: abpC(1-348: 449-857): GFP | abpC | aberrant phototaxis | aberrant actin filament organization |
DBS0237946 | abpC-/ [act15]: abpC(1-556: 644-857): GFP | abpC | aberrant phototaxis | aberrant actin filament organization |
DBS0237941 | abpC-/ [act15]: abpC(1-739): GFP | abpC | aberrant phototaxis |
DBS0351553 | abpC-/ [act15]: qkgA(425-1553) | abpC | qkgA-1 | qkgA-2 | aberrant actin filament polymerization |
DBS0349852 | abpE-/ [act15]: abpE | abpE-1 | abpE-2 | decreased phagocytosis |
DBS0350720 | acaA-/ [acaA-agg]: acaA: myc | acaA | decreased gene expression | decreased fruiting body size |
DBS0350721 | acaA-/ [acaA-psp]: acaA: myc | acaA | decreased gene expression | decreased mound size | decreased fruiting body size |
DBS0350722 | acaA-/ [acaA-pst]: acaA: myc | acaA | wild type |
DBS0350702 | acaA-/ [act15]: HA: pkaC | acaA | pkaC | wild type | delayed development | decreased cAMP level |
DBS0350725 | acaA-/ [act15]: HA: pkaC/ acrA- | acaA | acrA | pkaC | decreased gene expression | abolished adenylate cyclase activity | development arrests at tipped mound stage |
DBS0350737 | acaA-/ [act15]: acaA | acaA | aberrant slug development |
DBS0350738 | acaA-/ [act15]: acaA(1-390;398-1407) | acaA | abolished aggregation |
DBS0350739 | acaA-/ [act15]: acaA(L394T/ K482N) | acaA | wild type |
DBS0350735 | acaA-/ [act15]: pkaR(G135E/ G261A) | acaA | pkaR | increased cAMP level |
DBS0350736 | acaA-/ [unk]: acaA(F306L/ S498G,K504E,E593V,I649T) | acaA | decreased gene expression | abolished oscillatory cAMP signaling | decreased cAMP level |
DBS0350734 | acaA-/ [unk]: acaA(N333D,G633S) | acaA | abolished adenylate cyclase activity |
DBS0350733 | acaA-/ [unk]: acaA(V427I,S642F) | acaA | abolished activation of adenylate cyclase activity |
DBS0350711 | acaA-/ [unk]: acgA | acaA | acgA | aberrant sorocarp development |
DBS0350055 | acapA-/ [act15]: acapA(R633Q): GFP | acapA | aberrant filopodium formation | aberrant lysosome organization |
DBS0350054 | acapA-/ [act15]: acapA: GFP | acapA | increased filopodium formation |
DBS0350723 | acrA-/ [act15]: acaA(L394S) | acaA | acrA | precocious spore germination |
DBS0237786 | acrA-/ [act15]: acgA(1-401) | acgA | acrA | decreased prespore gene expression | decreased prespore cell differentiation | decreased sporulation |
DBS0350724 | acrA-/ [pkaC]: pkaC | acrA | pkaC | decreased spore germination | decreased fruiting body size | precocious development | decreased sporulation |
DBS0351190 | adcC-/ [act15]: adcC(1-485) | adcC | decreased protein localization to plasma membrane |
DBS0351189 | adcC-/ [act15]: adcC(101-654): GFP | adcC | abolished protein localization to plasma membrane |
DBS0235473 | alrA-/ [act15]: alrA | alrA | wild type |
DBS0235488 | alxA-/ [act15]: FLAG: alxA | alxA | delayed development |
DBS0235476 | alxA-/ [act15]: alxA(1-596): myc2 | alxA | aberrant standing slug morphology |
DBS0235477 | alxA-/ [act15]: alxA(1-697): myc2 | alxA | wild type |
DBS0235478 | alxA-/ [act15]: alxA(155-697): myc2 | alxA | aberrant standing slug morphology |
DBS0235479 | alxA-/ [act15]: alxA(293-697): myc2 | alxA | aberrant standing slug morphology |
DBS0235480 | alxA-/ [act15]: alxA(460-794): myc2 | alxA | aberrant standing slug morphology |
DBS0235481 | alxA-/ [act15]: alxA(D310A/ N311A) | alxA | wild type |
DBS0235482 | alxA-/ [act15]: alxA(Q181E/ Q183) | alxA | wild type |
DBS0235483 | alxA-/ [act15]: alxA(S700A/ S704A/ S708A) | alxA | wild type |
DBS0235484 | alxA-/ [act15]: alxA(S700D/ S704D/ S708D) | alxA | wild type |
DBS0235485 | alxA-/ [act15]: alxA(Y315D) | alxA | wild type |
DBS0235486 | alxA-/ [act15]: alxA(Y315F) | alxA | wild type |
DBS0235487 | alxA-/ [act15]: alxA: myc2 | alxA | wild type |
DBS0349953 | ampA/ [ampA]: TAP | ampA | increased protein secretion | development arrests at mound stage |
DBS0235495 | ampA/ [ampA]: ampA | ampA | decreased cell-substrate adhesion | increased pinocytosis | increased actin filament polymerization | aberrant chemotaxis to folate | increased pseudopodium formation |
DBS0349952 | ampA/ [ampA]: ampA/ lmbd2B- | ampA | lmbd2B | aberrant chemotaxis |
DBS0235501 | amtC-/ [act15]: cudA | amtC | cudA | delayed culmination |
DBS0235502 | amtC-/ [ecmA]: cudA | amtC | cudA | delayed culmination |
DBS0235503 | amtC-/ [pspA]: cudA | amtC | cudA | development arrests at slug stage |
DBS0305085 | apm2-/ [dscB]: GFP: vamp7A | apm2 | vamp7A | increased protein localization to plasma membrane |
DBS0305083 | apm3-/ [dscB]: GFP: vamp7A | apm3 | vamp7A | increased protein localization to plasma membrane |
DBS0235510 | aprA-/ [act15]: aprA | aprA | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0350009 | aprA-/ [act15]: bzpN: GFP | aprA | bzpN | abolished negative regulation of vegetative growth |
DBS0238085 | atg1-/ [act15]: atg1 | atg1 | wild type |
DBS0238092 | atg1-/ [act15]: atg1(1-628) | atg1 | aberrant cellular response to nitrogen starvation | abolished aggregation |
DBS0238087 | atg1-/ [act15]: atg1(K36A) | atg1 | aberrant cellular response to nitrogen starvation | abolished aggregation |
DBS0238089 | atg1-/ [act15]: atg1(K36A/ 1-628) | atg1 | aberrant cellular response to nitrogen starvation | abolished aggregation |
DBS0351576 | atg5-/ abpB-/ [dscB]: abpB(D93A/ D95A/ D97A): GFP | abpB | atg5 | aberrant cellular component organization | abolished vegetative growth |
DBS0351477 | atg7-/ [act15]: YFP: atg7(C563A) | atg7 | aberrant sorus morphology | decreased spore germination | delayed development |
DBS0351479 | atg7-/ [act15]: pkaC: YFP | atg7 | pkaC | decreased gene expression | decreased sporulation |
DBS0305978 | atg9-/ [act15]: GFP: atg9 | atg9 | wild type |
DBS0305979 | atg9-/ [act15]: atg9: GFP | atg9 | wild type |
DBS0351589 | atg9-/ [act15]: cdcD(R154C/ E219K): RFP | atg9 | cdcD | wild type |
DBS0351480 | atg9-/ [act15]: pkaC: YFP | atg9 | pkaC | abolished sporulation |
DBS0351266 | carA-/ [act15]: gpbA: YFP | carA-1 | carA-2 | gpbA | abolished aggregation |
DBS0350568 | carA-/ carC-/ [act15]: carA(261-359;S299A,S302G,S303G,S304G,S308A,S324G,S325A,S331A)(369-392;S383A,S385A) | carA-1 | carA-2 | carC | abolished stream development | aberrant activation of adenylate cyclase activity | aberrant chemotaxis to cAMP | aberrant oscillatory cAMP signaling | aberrant actin filament polymerization |
DBS0350436 | cdk8-/ [act15]: myc: cdk8 | cdk8 | wild type |
DBS0350437 | cdk8-/ [act15]: myc: cdk8(D194A) | cdk8 | decreased spore germination | abolished aggregation |
DBS0306227 | cenB-/ [act15]: RFP: cenB | cenB | wild type |
DBS0350010 | cfaD-/ [act15]: bzpN: GFP | bzpN | cfaD | abolished negative regulation of vegetative growth |
DBS0302446 | cfaD-/ [act15]: cfaD | cfaD | wild type |
DBS0350090 | chcA-/ [act15]: GFP: ap2a1 | ap2a1-1 | ap2a1-2 | chcA | increased protein localization |
DBS0302455 | chcA-/ [act15]: epnA: GFP | chcA | epnA | aberrant protein localization to clathrin-coated pit |
DBS0350091 | chcA-/ [act15]: gppA: GFP | chcA | gppA | aberrant protein localization to plasma membrane |
DBS0235604 | clc-/ [act15]: GFP-clc(146-194) | clc | abolished cytokinesis | wild type | aberrant fruiting body morphogenesis |
DBS0235605 | clc-/ [act15]: GFP-clc(85-124) | clc | abolished cytokinesis | wild type | aberrant fruiting body morphogenesis |
DBS0235607 | clc-/ [act15]GFP: clc(1-124) | clc | abolished cytokinesis | wild type | aberrant fruiting body morphogenesis |
DBS0350474 | cln3-/ [act15]: GFP: cln3 | cln3 | wild type |
DBS0350309 | cnrF-/ [act15]: cnrF: RFP | cnrF | wild type |
DBS0302656 | cnrN-/ [act15]: cnrN | cnrN | wild type |
DBS0351521 | corA-/ [act15]: FLAG: corA(1-432) | corA | abolished aggregation |
DBS0350345 | corA-/ [act15]: GFP: mhkA | corA | mhkA | wild type |
DBS0350346 | corA-/ [act15]: GFP: mhkB | corA | mhkB | wild type |
DBS0350344 | corA-/ [act15]: GFP: mhkC | corA | mhkC | decreased catalytic activity | wild type |
DBS0350343 | corA-/ [act15]: GFP: pakA(797-1197) | corA | pakA | wild type |
DBS0350371 | corA-/ [act15]: corA | corA | wild type |
DBS0238320 | cpnA-/ [act15]: GFP: cpnA | cpnA | delayed hypotonic response | decreased culmination | delayed development |
DBS0349922 | ctxA-/ [act15]: GFP-mhcA | ctxA | aberrant protein localization to basolateral plasma membrane | aberrant stalk morphogenesis | aberrant development of tipped mound |
DBS0350293 | ctxA-/ ctxB-/ [act15]: GFP: arcA | arcA | ctxA | ctxB | aberrant protein localization to cell cortex |
DBS0349972 | ctxA-/ ctxB-/ [act15]: acaA: YFP | acaA | ctxA | ctxB | aberrant fruiting body morphogenesis |
DBS0349973 | ctxA-/ ctxB-/ [act15]: carA: YFP | carA-1 | carA-2 | ctxA | ctxB | abolished stream development | abolished adenylate cyclase activity | development arrests at tight mound stage |
DBS0266761 | culB-/ [act15]: pkaC | culB | pkaC | abolished sporulation | precocious prestalk gene expression | abolished aggregation | abolished prespore gene expression |
DBS0349807 | detA-/ [act6]: GFP: detA | detA | wild type |
DBS0349816 | detA-/ [act6]: GFP: detA/ [act6]: 3xHA: culD | culD | detA | increased gene expression |
DBS0349817 | detA-/ [act6]: GFP: detA/ [act6]: 3xHA: repE | detA | repE | increased gene expression |
DBS0349813 | detA-/ [cotB]: GFP | detA | decreased prespore cell differentiation |
DBS0349811 | detA-/ [ecm0]: lacZ | detA | aberrant prestalk O cell differentiation |
DBS0349812 | detA-/ [ecmA0]: GFP | detA | increased prestalk cell differentiation |
DBS0349808 | detA-/ [ecmA0]: lacZ | detA | increased prestalk cell differentiation |
DBS0349809 | detA-/ [ecmA]: lacZ | detA | increased prestalk A cell differentiation |
DBS0349810 | detA-/ [ecmB]: lacZ | detA | delayed development |
DBS0350394 | dgat1-/ dgat2-/ [act15]: GFP: dgat2 | dgat1 | dgat2 | wild type |
DBS0235703 | dhkA-/ [pkaC]: pkaC | dhkA | pkaC | aberrant stalk morphogenesis |
DBS0235712 | dhkK-/ [act15]: dhkK(D1125N) | dhkK | aberrant fruiting body morphogenesis |
DBS0235719 | dia1-/ [act6]: trap1 | dia1 | trap1 | aberrant aggregation | decreased fruiting body size |
DBS0235903 | dimB-/ [act15]: dimA: GFP | dimA | dimB | abolished protein localization to nucleus |
DBS0235904 | dimB-/ [act15]: dimB: GFP | dimB | wild type |
DBS0349975 | dmtA-/ [dimB]: dimB | dimB | dmtA | decreased prestalk B cell differentiation |
DBS0238511 | drkC-/ [act15]: drkC(1-497): YFP | drkC | decreased phagocytosis |
DBS0238513 | drkC-/ [act15]: drkC(K518R): YFP | drkC | decreased phagocytosis |
DBS0350218 | drnB-/ [act15]: pre-miRNA | drnB | abolished pre-miRNA processing |
DBS0350210 | drnB-/ [act6]: lacZ/ [RNAi]lacZ | drnB | abolished production of siRNA involved in RNA interference | abolished transitive RNA interference |
DBS0302602 | dsgg-/ OE]: dsgg(Delta-Fbox) | dsgg | wild type |
DBS0302606 | dsgg-/ [OE]: GFP: lvsD | dsgg | lvsD | wild type |
DBS0302599 | dsgg-/ [OE]: dsgg | dsgg | wild type |
DBS0302601 | dsgg-/ [OE]: dsgg(Q551A) | dsgg | aberrant contractile vacuole organization |
DBS0302600 | dsgg-/ [OE]: dsggR515A) | dsgg | aberrant contractile vacuole organization |
DBS0302607 | dsgg-/ [OE]: lvsA | dsgg | lvsA | aberrant contractile vacuole organization |
DBS0302611 | dsgg-/ [OE]: phgA | dsgg | phgA | aberrant contractile vacuole organization |
DBS0302678 | dsgg-/ [OE]: rab8A | dsgg | rab8A | aberrant contractile vacuole organization |
DBS0238237 | dstA-/ GFP: dstA(237-707): ORF+ | dstA | abolished culmination | decreased stalk length |
DBS0252824 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C | 2C | dstA | aberrant fruiting body morphogenesis |
DBS0252823 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 7E | 7E | dstA | hssB | wild type |
DBS0252826 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165 | DDB_G0276165 | dstA | aberrant fruiting body morphogenesis |
DBS0252825 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325 | DDB_G0282325 | dstA | aberrant fruiting body morphogenesis |
DBS0252816 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssA | dstA | hssA | wild type |
DBS0252822 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssB | dstA | hssB | wild type |
DBS0350804 | ehd-/ [act15]: dymA: GFP | dymA | ehd | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle |
DBS0302598 | elmoA-/ [act15]: elmoA(1-903/ 959-977): GFP | elmoA | decreased cell motility | increased phagocytosis |
DBS0302591 | elmoA-/ [act15]: elmoA: GFP | elmoA | wild type |
DBS0302457 | epnA-/ [act15]: GFP: epnA(253-677) | epnA | aberrant spore morphology | abolished protein localization to plasma membrane | abolished protein localization to clathrin-coated pit |
DBS0302456 | epnA-/ [act15]: epnA(1-133): GFP | epnA | aberrant localization to coated pits |
DBS0302474 | epnA-/ [act15]: epnA(R65A/ K78A): GFP | epnA | aberrant spore morphology | abolished protein localization to plasma membrane | abolished phosphatidylinositol-4,5-bisphosphate binding | abolished protein localization to clathrin-coated pit | abolished protein phosphorylation |
DBS0302475 | epnA-/ [act15]: epnA(T107A): GFP | epnA | aberrant spore morphology | abolished protein localization to plasma membrane |
DBS0302454 | epnA-/ [act15]: epnA: GFP | epnA | wild type |
DBS0235948 | eppA-/ [act6]: myc: eppA | eppA | wild type |
DBS0350681 | erkA-/ [act15]: gpaE | erkA | gpaE | wild type |
HR42 | fbxA-/ [act15]: myc: fbxA | fbxA | abolished culmination | decreased sporulation |
DBS0304905 | forC-/ [act15]: GFP: forC | forC | wild type |
DBS0235971 | forH-/ [act15]: GFP: forH | forH | increased filopodium formation | decreased cell motility | increased cell-substrate adhesion |
DBS0304440 | frmA-/ [unk]: GFP | frmA | decreased gene expression | aberrant sorocarp development | increased cell-cell adhesion | delayed development | abolished phototaxis |
DBS0305026 | gabT-[pkaC]: pkaC | gabT | pkaC | aberrant protein secretion |
DBS0304912 | gbpC-/ [act15]: gbpC | gbpC | wild type |
DBS0304917 | gbpC-/ [act15]: gbpC(1-1698: 2005-2631) | gbpC | decreased chemotaxis to cAMP |
DBS0349868 | gbpC-/ [act15]: gbpC(1-2331: 2470-2631): GFP | gbpC | aberrant stream morphology | decreased chemotaxis to cAMP |
DBS0304918 | gbpC-/ [act15]: gbpC(311-2631) | gbpC | decreased chemotaxis to cAMP |
DBS0304916 | gbpC-/ [act15]: gbpC(F1892A) | gbpC | decreased chemotaxis to cAMP |
DBS0304915 | gbpC-/ [act15]: gbpC(F2082A/ E2084A/ F2564A/ E2566A) | gbpC | decreased chemotaxis to cAMP |
DBS0304913 | gbpC-/ [act15]: gbpC(K342N) | gbpC | decreased chemotaxis to cAMP |
DBS0304914 | gbpC-/ [act15]: gbpC(K905W) | gbpC | decreased chemotaxis to cAMP |
DBS0235998 | gbpD-/ [act15]: gbpD | gbpD | increased lateral pseudopodium formation | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant actin filament organization | abolished aggregation |
DBS0350387 | gcsA-/ [act15]: carA | carA-1 | carA-2 | gcsA | abolished aggregation |
DBS0350388 | gcsA-/ [act15]: yakA | gcsA | yakA | wild type |
DBS0237190 | gdt1-/ [act15]: pkaR(G135E/ G261A) | gdt1 | pkaR | increased gene expression | abolished aggregation |
DBS0350449 | gefA-/ [dscB]: rasG(S17N) | gefA | rasG | decreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | decreased protein kinase activation |
DBS0304985 | gefQ-/ [act15]: GFP: gefQ(172-654) | gefQ | abolished guanyl-nucleotide exchange factor activity | decreased phototaxis |
DBS0304986 | gefQ-/ [act15]: GFP: gefQ(910-1298) | gefQ | decreased phototaxis |
DBS0238390 | gnt15-/ [act15]: FLAG: gnt15 | gnt15 | wild type |
DBS0238391 | gnt15-/ [act15]: FLAG: gnt15 | gnt15 | wild type |
DBS0236092 | gpaA-/ [gpaA]: gpaA(G45V) | gpaA | delayed development |
DBS0236093 | gpaA-/ [gpaA]: gpaA(Q206L) | gpaA | increased basal disc size |
JM1 | gpaB-/ [OE]: carA | carA-1 | carA-2 | gpaB | aberrant calcium-mediated signaling |
DBS0236096 | gpaB-/ [act15]: gpaB | gpaB | abolished aggregation |
DBS0266942 | gpaB-/ [act15]: gpaB | gpaB | delayed aggregation |
DBS0266939 | gpaB-/ [act15]: gpaB(1-345): gpaD(337-345) | gpaB | gpaD | abolished aggregation |
DBS0351103 | gpaB-/ [act15]: gpaB(C4A) | gpaB | abolished protein localization to plasma membrane | decreased cGMP-mediated signaling | abolished aggregation |
DBS0237137 | gpaB-/ [act15]: gpaB(D154V) | gpaB | aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate |
DBS0237138 | gpaB-/ [act15]: gpaB(E190G) | gpaB | aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling |
DBS0351105 | gpaB-/ [act15]: gpaB(G207A) | gpaB | abolished protein localization to plasma membrane |
DBS0351104 | gpaB-/ [act15]: gpaB(G2A) | gpaB | abolished protein localization to plasma membrane |
DBS0237139 | gpaB-/ [act15]: gpaB(I104S) | gpaB | aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate |
DBS0237140 | gpaB-/ [act15]: gpaB(L110S) | gpaB | aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate |
DBS0237141 | gpaB-/ [act15]: gpaB(L76P) | gpaB | abolished aggregation |
DBS0237142 | gpaB-/ [act15]: gpaB(N74D) | gpaB | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate | abolished aggregation |
DBS0237143 | gpaB-/ [act15]: gpaB(R64G) | gpaB | decreased chemotaxis rate | abolished aggregation |
DBS0237144 | gpaB-/ [act15]: gpaB(S155P) | gpaB | decreased chemotaxis rate | abolished aggregation |
DBS0351217 | gpaB-/ [act15]: gpaI | gpaB | gpaI | wild type |
DBS0351214 | gpaB-/ [act15]: rasG(S17N) | gpaB | rasG | abolished activation of GTPase activity |
DBS0236097 | gpaB-/ [gpaA]: gpaB | gpaB | abolished aggregation |
DBS0236099 | gpaB-/ [gpaB]: gpaB | gpaB | wild type |
DBS0266944 | gpaD-/ [act15]: gpaB | gpaB | gpaD | aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis |
DBS0266946 | gpaD-/ [act15]: gpaB(1-345): gpaD(337-345) | gpaB | gpaD | aberrant fruiting body morphogenesis | decreased cGMP biosynthesis |
DBS0266943 | gpaD-/ [act15]: gpaD | gpaD | wild type |
DBS0266945 | gpaD-/ [act15]: gpaE | gpaD | gpaE | aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis |
DBS0266947 | gpaD-/ [act15]: gpaE(1-339): gpaD(337-345) | gpaD | gpaE | aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis |
DBS0266941 | gpaE-/ [act15]: gpaE | gpaE | precocious development of tipped mound |
DBS0266948 | gpaE-/ [act15]: gpaE(1-339): gpaD(337-345) | gpaD | gpaE | precocious development of tipped mound |
DBS0350678 | gpaE-/ [act15]: gpaE(K10E/ K11E) | gpaE | delayed development of tipped mound | delayed gene expression |
DBS0350470 | gpbA-/ [act15]: GFP: cap | cap | gpbA | decreased phagocytosis |
LW14 | gpbA-/ [act15]: carA | carA-1 | carA-2 | gpbA | aberrant calcium-mediated signaling | decreased protein kinase activation | abolished aggregation |
LW17 | gpbA-/ [act15]: carC | carC | gpbA | abolished aggregation |
DBS0351260 | gpbA-/ [act15]: gpbA(A99T/ Y271H/ C335M) | gpbA | abolished activation of adenylate cyclase activity | aberrant fruiting body morphogenesis |
DBS0351261 | gpbA-/ [act15]: gpbA(M30V/ K85R/ S104P/ Q163H) | gpbA | development arrests at mound stage | abolished activation of adenylate cyclase activity | decreased chemotaxis to cAMP |
DBS0351263 | gpbA-/ [act15]: gpbA(M48T/ I52T/ E310G) | gpbA | wild type | decreased activation of adenylate cyclase activity | decreased gene expression | aberrant slug development |
DBS0351259 | gpbA-/ [act15]: gpbA(N147D/ H149R/ N237S) | gpbA | development arrests at mound stage | abolished activation of adenylate cyclase activity | abolished chemotaxis to cAMP |
DBS0351264 | gpbA-/ [act15]: gpbA(R13G/ N74S/ S79P/ H149R/ V178A/ V194R/ F293L) | gpbA | decreased activation of adenylate cyclase activity | decreased gene expression | development arrests at tipped mound stage |
DBS0351262 | gpbA-/ [act15]: gpbA(S196G/ V199D/ C211R) | gpbA | decreased activation of adenylate cyclase activity | aberrant fruiting body morphogenesis |
DBS0351258 | gpbA-/ [act15]: gpbA(V88A/ F229S/ D235V) | gpbA | abolished activation of adenylate cyclase activity | aberrant fruiting body morphogenesis | decreased chemotaxis to cAMP |
HO547 | gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: CFP: FKBP/ [act15]: limE(1-145): GFP | gpbA | aberrant cortical actin cytoskeleton organization |
HO543 | gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: YFP: FKBP | gpbA | abolished chemotaxis to folate |
DBS0351198 | gpbA-/ [act6]: yakA | gpbA | yakA | abolished vegetative growth |
DBS0350479 | gpr89-/ [act15]: gpr89: GFP | gpr89 | wild type |
DBS0304815 | grlA-/ [act15]: grlA: GFP | grlA | aberrant development of tipped mound |
DBS0351147 | grlH-/ [act15]: grlH | grlH | wild type |
DBS0238866 | grlJ-/ [act15]: grlJ: GFP | grlJ | wild type |
DBS0350284 | grlJ-/ [act15]: grlJ: GFP | grlJ | wild type |
DBS0238687 | grpA-/ [act15]: grpA-FLAG | grpA | wild type |
DBS0349930 | gskA-/ [act15]: GFP: tacA | gskA | tacA | increased protein localization to nucleus |
DBS0349881 | gskA-/ [act15]: gskA(Y214F) | gskA | abolished stream development |
DBS0350260 | gskA-/ [unk]: pikA(1-492(S7D/ S11D/ S109D/ S113D/ S177D/ S181D)) | gskA | pikA | wild type |
DBS0350348 | gtaC-/ [act15]: GFP: gtaC | gtaC | wild type |
DBS0350357 | gtaC-/ [act15]: GFP: gtaC(C500,503,522,525S) | gtaC | aberrant gene expression | abolished aggregation | decreased fruiting body size |
DBS0350358 | gtaC-/ [act15]: GFP: gtaC(T376A/ S379,380A/ C500,503,522,525S) | gtaC | aberrant protein localization to nucleus |
DBS0350361 | gtaC-/ [act15]: gtaC: (468-496): GFP: gtaC | gtaC | development arrests at mound stage | decreased mound size | precocious development |
DBS0350257 | gxcC-/ [act15]: GFP: gxcC | gxcC | wild type |
DBS0350269 | gxcT-/ [act15]: GFP: gxcT | gxcT | wild type |
DBS0350656 | hatA-/ [hatB]: hatB | hatA | hatB | aberrant cellular response to stress |
DBS0350289 | hspc300-/ [act15]: myc: hspc300 | hspc300 | wild type |
DBS0252702 | icmA-/ [act15]: TAP: YFP: rasG | icmA-1 | icmA-2 | rasG | abolished C-terminal protein methylation |
DBS0238521 | icpA-/ [act15]: GFP: icpA(1-1013) | icpA | aberrant protein localization to mitotic spindle |
DBS0350439 | iplA-/ [act15]: GFP: iplA | iplA | wild type |
DBS0351436 | ireA-/ [act15]: ireA(K603N): GFP | ireA | decreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress |
DBS0351437 | ireA-/ [act15]: ireA(N927A): GFP | ireA | decreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress |
DBS0350959 | kif10-/ [act15]: dhcA(1384-4725) | dhcA | kif10 | wild type |
DBS0350022 | kif5-/ [act15]: FLAG: kif5 | kif5 | aberrant cytokinesis | aberrant cell morphology |
DBS0350023 | kif5-/ [act15]: FLAG: kif5(342-990) | kif5 | aberrant cell morphology |
DBS0350024 | kif5-/ [act15]: GFP: kif5(805-990) | kif5 | aberrant cytokinesis |
DBS0350947 | kif8-/ [act15]: dhcA(1384-4725) | dhcA | kif8 | wild type |
DBS0350044 | kil2-/ [act15]: kil1 | kil1 | kil2 | abolished defense response to bacterium |
DBS0236493 | krsA-/ [act15]: GFP: krsA | krsA | wild type |
DBS0238721 | krsA-/ [act15]: GFP: krsA | krsA | wild type |
DBS0238722 | krsA-/ [act15]: GFP: krsA(K49R) | krsA | aberrant stream morphology |
DBS0238723 | krsA-/ [act15]: GFP: krsA(T173A) | krsA | abolished stream development |
DBS0238725 | krsA-/ [act15]: GFP: krsA(deltaC) | krsA | aberrant stream morphology |
DBS0238724 | krsA-/ [act15]: GFP: krsA(deltaKinase) | krsA | abolished stream development |
DBS0238726 | krsA-/ [act15]: GFP: krsA(deltaNS) | krsA | abolished stream development |
DBS0350537 | ku80-/ myc: ku80(1-782) | ku80 | decreased double-strand break repair via nonhomologous end joining |
DBS0350453 | lpten-/ [act15]: lpten: RFP | lpten | wild type |
DBS0350036 | mekA-/ [act15]: mekA(299-360) | mekA | decreased mound size |
DBS0350035 | mekA-/ [act15]: mekA(K321A) | mekA | decreased mound size |
DBS0350032 | mekA-/ [act15]: mekA(S444A/ T448A) | mekA | decreased mound size |
DBS0238109 | mekA-/ ppp4C-/ [act15]: FLAG: pppC | ppp4c | decreased mound size | precocious development |
DBS0266674 | mhcA-/ [act15]: GFP: abpC(9-148) | abpC | mhcA | decreased uropod retraction | decreased pseudopodium retraction |
DBS0266675 | mhcA-/ [act15]: GFP: mhcA(E476K) | mhcA | decreased pseudopodium retraction |
DBS0350489 | mhcA-/ [act15]: GFP: mhcA/ [RNAi]rmd1 | mhcA | rmd1 | abolished protein localization to cleavage furrow |
DBS0236548 | mhcA-/ [act15]: GFP: pats1(2087-2351) | mhcA | pats1 | aberrant cytokinesis |
DBS0350291 | mhcA-/ [act15]: gppA: GFP | gppA | mhcA | aberrant contractile vacuole morphology | decreased contractile vacuole discharge |
DBS0236549 | mhcA-/ [act15]: limE(1-145): GFP | limE | mhcA | increased actin filament polymerization |
DBS0350808 | mhcA-/ [act15]: mhcA(1-933: 1455-2116] | mhcA | wild type | aberrant cytokinesis | aberrant fruiting body morphogenesis |
DBS0238158 | mhcA-/ [act15]: mhcA(81-2116) | mhcA | decreased growth rate | development arrests at tipped mound stage |
DBS0236550 | mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A) | mhcA | decreased filopodium formation |
DBS0236551 | mhcA-/ [act15]: mhcA(T1823D/ T1833D/ T2029D) | mhcA | increased filopodium formation |
DBS0350948 | mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(E683K) | mhcA | aberrant catalytic activity |
DBS0350949 | mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R686C) | mhcA | aberrant catalytic activity |
DBS0238157 | mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R689H) | mhcA | decreased actin filament sliding |
DBS0236557 | mhkA-/ [act15]: mhkA | mhkA | decreased growth rate | development arrests at mound stage | aberrant cytokinesis | decreased myosin II assembly |
DBS0351180 | midA/ [act15]: midA(E200A) | midA | aberrant cellular homeostasis | decreased growth rate | decreased phototaxis |
DBS0351182 | midA/ [act15]: midA(G170V/ G172V) | midA | aberrant cellular homeostasis | decreased growth rate | decreased phototaxis |
DBS0351181 | midA/ [act15]: midA(N205A) | midA | aberrant cellular homeostasis | decreased growth rate | decreased phototaxis |
DBS0238058 | mlcE-/ [act15]: myc: mlcE | mlcE | wild type |
DBS0349919 | mlkA-/ [act15]: GFP-mhcA | mlkA | aberrant stalk morphogenesis |
DBS0266904 | mpl1-/ [act15]: flag: mpl1 | mpl1 | wild type |
DBS0350391 | mrfA-/ [act15]: myc: mrfA(K772A): FLAG | mrfA | aberrant protein modification |
DBS0350390 | mrfA-/ [act15]: myc: mrfA(S767A): FLAG | mrfA | aberrant protein modification | delayed development |
DBS0350389 | mrfA-/ [act15]: myc: mrfA: FLAG | mrfA | wild type |
DBS0350990 | myoA-/ myoB-/ [act15]: myoB | myoA | myoB | delayed aggregation |
DBS0350991 | myoA-/ myoB-/ [act15]: myoB(1-1057) | myoA | myoB | decreased pinocytosis | decreased growth rate | aberrant actin filament organization |
DBS0350992 | myoA-/ myoB-/ [act15]: myoB(S332) | myoA | myoB | decreased pinocytosis | decreased growth rate | aberrant actin filament organization |
DBS0351378 | myoB-/ [act15]: GFP: myoB(1-720) | myoB | abolished protein localization to plasma membrane |
DBS0351379 | myoB-/ [act15]: GFP: myoB(1-800,813-1111) | myoB | abolished protein localization to actin wave | abolished protein localization to plasma membrane |
DBS0351380 | myoB-/ [act15]: GFP: myoB(713-1111) | myoB | abolished protein localization to leading edge |
DBS0351367 | myoB-/ [act15]: myoB(S332A) | myoB | abolished protein phosphorylation |
DBS0266889 | myoI-/ [act15]: GFP: myoI | myoI | wild type |
DBS0351400 | myoI-/ [act15]: GFP: myoI(1-1020) | myoI | abolished protein localization to pseudopodium | decreased filopodium formation |
DBS0351398 | myoI-/ [act15]: GFP: myoI(2057-2357) | myoI | increased filopodium formation |
DBS0266890 | myoI-/ [act15]: GFP: myoI(809-1154) | myoI | decreased phagocytosis |
DBS0351399 | myoI-/ [act15]: GFP: myoI(K23333A,K2336A) | myoI | increased filopodium formation |
DBS0237617 | myoI-/ [act15]: gbpD | gbpD | myoI | increased cell-substrate adhesion | aberrant cell morphology | increased pseudopodium formation |
DBS0349846 | myoK-/ [act15]: YFP: myoK(1-121: 262-858) | myoK | decreased phagocytosis |
DBS0349850 | myoK-/ [act15]: myoK | myoK | increased phagocytosis |
DBS0349854 | myoK-/ [act15]: pakB(1-337: 563-852) | myoK | pakB | wild type |
DBS0349841 | nhe1-/ [act15]: mhcA: GFP | mhcA | nhe1 | abolished protein localization to trailing edge |
DBS0236611 | noxA-/ [act15]: noxA: myc2 | noxA | aberrant fruiting body morphogenesis |
DBS0236702 | nxnA-/ [act15]: GFP: nxnB | nxnA | nxnB | development arrests at mound stage |
DBS0238362 | p2xA-/ [act15]: p2xA: GFP | p2xA | wild type |
DBS0350014 | pah-/ [act15]: 6xHis: pah | pah | wild type |
DBS0350016 | pah-/ [act15]: 6xHis: pah(92-415) | pah | abolished vegetative growth |
DBS0350015 | pah-/ [act15]: 6xHis: pah(92-441) | pah | wild type |
DBS0350810 | pakA-/ [act15]: pakA(T579A) | pakA | decreased chemotaxis to cAMP |
DBS0349889 | pakA-/ [act15]: pakA: GFP | pakA | wild type |
DBS0350428 | pakB-/ [act15]: RFP: abpE | abpE-1 | abpE-2 | pakB | decreased chemotaxis to cAMP | aberrant establishment or maintenance of cell polarity | abolished aggregation | abolished protein localization to leading edge |
DBS0350430 | pakB-/ [act15]: RFP: abpE/ [act15]: GFP: pak(1-180) | abpE-1 | abpE-2 | pakB | wild type |
DBS0350282 | pakD-/ [act15]: pakD | pakD | development arrests at mound stage |
DBS0350395 | pakD-/ [act15]: pakD: GFP | pakD | wild type |
DBS0350973 | paxB-/ [act15]: gpaH | gpaH | paxB | aberrant cytokinesis |
DBS0350094 | paxB-/ [act15]: pldB | paxB | pldB | wild type | increased phagocytosis |
DBS0350893 | pdeD-/ pdeE-/ [unk]: pdeE | pdeD | pdeE | delayed aggregation |
DBS0236747 | pefB-/ noxA-/ [act15]: pefB | noxA | pefB | aberrant sorocarp development |
DBS0304869 | phg1A-/ [act15]: phg1A(1-276): phg1B221-587) | phg1A | phg1B | decreased phagocytosis |
DBS0304868 | phg1A-/ [act15]: phg1B | phg1A | phg1B | increased secretion of lysosomal enzymes | wild type | decreased cell-substrate adhesion | aberrant protein level | decreased phagocytosis |
DBS0304870 | phg1A-/ [act15]: phg1B(1-220): phg1a(277-642) | phg1A | phg1B | decreased phagocytosis |
DBS0237615 | phg2-/ [act15]: gbpD | gbpD | phg2 | aberrant cell morphology | abolished chemotaxis to cAMP | increased pseudopodium formation |
DBS0302610 | phgA-/ [OE]: dsgg | dsgg | phgA | aberrant contractile vacuole organization |
DBS0351455 | piaA(G917D)/ [unk]: GFP: piaA(G963E) | piaA | abolished aggregation |
DBS0350471 | pikA-/ pikB-/ [act15]: GFP: cap | cap | pikA | pikB | wild type |
DBS0351206 | pirA-/ pirA(K193D/ R194D): EGFP | pirA | abolished protein localization to cell periphery | decreased protein phosphorylation |
DBS0350708 | pkaC-/ [act6]: pkaC(303-648) | pkaC | wild type |
DBS0350707 | pkaC-/ [act6]: pkaC(330-648) | pkaC | abolished aggregation |
DBS0350919 | pkcA-/ [act15]: pldB | pkcA | pldB | aberrant aggregation | decreased sporulation |
DBS0267125 | plc-/ [OE]: dagA(PH): GFP/ [OE]: plc | dagA | plc | increased protein localization to plasma membrane | decreased chemotaxis to cAMP |
DBS0350047 | plc-/ [act15]: pten: GFP | plc | pten | wild type | aberrant protein localization to cytoplasm |
DBS0236797 | pldB-/ [act15]: pldB: GFP | pldB | abolished aggregation |
DBS0351356 | ppk1-/ [act15]: GFP: hsp48 | hsp48 | ppk1 | decreased protein level |
DBS0236825 | ppk1-/ [act15]: ppk1 | ppk1 | wild type |
DBS0238110 | ppp4C-/ [act15]: smkA | ppp4c | smkA | development arrests at mound stage | delayed development |
DBS0238034 | proC-/ [unk]: FLAG: proC | proC | wild type |
DBS0350305 | psenA-/ psenB-/ [act15]: GFP: psenB | psenA | psenB | wild type |
DBS0350306 | psenA-/ psenB-/ [act15]: psenB(D348A/ D394A) | psenA | psenB | wild type |
DBS0302356 | psrA-/ [act15]: FLAG: gskA | gskA | psrA | increased protein kinase activation |
DBS0302357 | psrA-/ [act15]: gskA(K84M/ K85M) | gskA | psrA | decreased culmination | decreased prespore gene expression | delayed development | increased protein kinase activation |
DBS0350829 | psrA-/ [unk]: FLAG: rasD(G12T) | psrA | rasD | increased protein kinase activation |
DBS0350454 | pten-/ [act15]: lpten: RFP | lpten | pten | wild type |
DBS0349890 | pten-/ [act15]: pakA: GFP | pakA | pten | aberrant cytokinesis |
DBS0350754 | pten-/ [act15]: pten(186-515): GFP | pten | aberrant sorocarp development | decreased chemotaxis to cAMP |
DBS0350755 | pten-/ [act15]: pten(C124S): GFP | pten | aberrant sorocarp development | decreased chemotaxis to cAMP |
DBS0351587 | pten-/ [act15]: pten(G129E) | pten | increased lateral pseudopodium formation | aberrant localization |
DBS0236831 | pten-/ [act15]: pten: GFP | pten | wild type |
DBS0349893 | pten-/ pakA-/ [act15]: pakA(T585A): GFP | pakA | pten | decreased chemotaxis to cAMP |
DBS0349900 | pten-/ pakA-/ [act15]: pakA(T585E): GFP | pakA | pten | aberrant cytokinesis | decreased chemotaxis to cAMP |
DBS0349899 | pten-/ pakA-/ [act15]: pakA: GFP | pakA | pten | aberrant cytokinesis |
DBS0350675 | ptpB-/ [act15]: 6xHis: erkA | erkA | ptpB | aberrant stream morphology |
DBS0350018 | qdpr-/ [act15]: pah | pah | qdpr | decreased growth rate |
DBS0350011 | qkgA-/ [act15]: bzpN: GFP | bzpN | qkgA-1 | qkgA-2 | abolished negative regulation of vegetative growth |
DBS0237191 | racC-/ [act15]: CFP: racC | racC | increased actin filament polymerization |
DBS0351348 | racE-/ [act15]: GFP: racE(G20V) | racE | decreased protein phosphorylation | decreased chemotaxis to cAMP |
DBS0351349 | racE-/ [act15]: GFP: racE(G23V) | racE | increased protein phosphorylation |
DBS0351350 | racE-/ [act15]: GFP: racE(S192D) | racE | increased protein phosphorylation | wild type |
DBS0351347 | racE-/ [act15]: GFP: racE(T25N) | racE | wild type |
DBS0351614 | racE-/ [act15]: GFP: racE(T25N/ S192D) | racE | wild type |
DBS0351351 | racE-/ [act15]: GFP: rasC(Q62L) | racE | rasC | decreased protein phosphorylation |
DBS0349949 | racE-/ [act15]: fttB | fttB | racE | decreased growth rate |
DBS0349946 | racE-/ [act15]: fttB: GFP | fttB | racE | abolished protein localization to cell cortex |
DBS0350956 | racE-/ [act15]racE(G20V) | racE | wild type |
DBS0350957 | racE-/ [act15]racE(T25N) | racE | abolished cytokinesis |
DBS0236844 | racF2(G12V) | racF2 | decreased cell-cell adhesion |
DBS0236845 | racF2(N17T) | racF2 | increased cell-cell adhesion | decreased sexual fusion |
DBS0350317 | rapgap9-/ [act15]: GFP: rapgap9 | rapgap9 | wild type |
DBS0237614 | rasC-/ [act15]: gbpD | gbpD | rasC | increased cell-substrate adhesion | aberrant cell morphology |
DBS0350740 | rasC-/ [rasC]: rasG | rasC | rasG | abolished activation of adenylate cyclase activity | abolished aggregation |
DBS0350742 | rasC-/ [rasC]: rasG(1-77(D30A)): rasC(79-189) | rasC | rasG | wild type |
DBS0350741 | rasC-/ [rasC]: rasG(D30A) | rasC | rasG | aberrant aggregation | decreased activation of adenylate cyclase activity |
DBS0266697 | rasC-/ rasG-/ [act15]: carA | carA-1 | carA-2 | rasC | rasG | decreased activation of adenylate cyclase activity | abolished activation of GTPase activity | decreased growth rate | abolished vegetative growth | abolished protein kinase activation | abolished cGMP-mediated signaling | abolished chemotaxis to cAMP |
DBS0350480 | rasC-/ rasG-/ [rasG]: rasD | rasC | rasD | rasG | decreased chemotaxis to folate |
DBS0350482 | rasC-/ rasG-/ [rasG]: rasD(1-104): rasG(103-189) | rasC | rasD | rasG | decreased chemotaxis to folate |
DBS0350481 | rasC-/ rasG-/ [rasG]: rasG | rasC | rasG | wild type |
DBS0350483 | rasC-/ rasG-/ [rasG]: rasG(1-104): rasD(103-187) | rasC | rasD | rasG | wild type |
DBS0351062 | rasC-/ rasG-/ [unk]: carA | carA-1 | carA-2 | rasC | rasG | decreased protein localization to plasma membrane |
DBS0351213 | rasC-[act15]: rasG(S17N) | rasC | rasG | abolished activation of GTPase activity | decreased chemotaxis to cAMP |
DBS0236864 | rasG-/ [OE]: rasB | rasB | rasG | decreased growth rate |
DBS0350448 | rasG-/ [dscB]: rasG(S17N) | rasG | decreased positive regulation of GTPase activity | decreased actin filament polymerization | decreased protein kinase activation | decreased chemotaxis to cAMP |
DBS0349996 | rblA-/ [act15]: GFP/ [act15]: myc: btg | btg | rblA | increased cell migration to prestalk region |
DBS0235706 | regA-/ [act15]: dhkK(D1125N) | dhkK | regA | aberrant fruiting body morphogenesis | precocious development |
DBS0351475 | regA-/ [act15]: erkA | erkA | regA | delayed slug development |
DBS0351472 | regA-/ [act15]: regA(R588A,R589A,L594A,I595A,L596A) | regA | delayed development |
DBS0351284 | regA-/ [act15]: regA(S142A) | regA | aberrant fruiting body morphogenesis | precocious development |
DBS0351283 | regA-/ [act15]: regA(S142E) | regA | delayed development |
DBS0351285 | regA-/ [act15]: regA(S413A) | regA | increased mound size | delayed development |
DBS0351286 | regA-/ [act15]: regA(S413E) | regA | increased mound size | delayed development |
DBS0351287 | regA-/ [act15]: regA(T676A) | regA | delayed sporulation |
DBS0351288 | regA-/ [act15]: regA(T676E) | regA | aberrant fruiting body morphogenesis | precocious development |
DBS0349921 | rgaA-/ [act15]: GFP-mhcA | rgaA | aberrant stalk morphogenesis | aberrant development of tipped mound | abolished protein localization to apical plasma membrane |
DBS0350020 | rgfA-/ [act15]: rgfA | rgfA | decreased chemotaxis to folate | delayed development |
DBS0350193 | ric8-/ [act15]: GFP: ric8 | ric8 | wild type |
DBS0350219 | rrpC-/ [act15]: pre-miRNA | rrpC | increased pre-miRNA processing |
DBS0350974 | sadA-/ [act15]: gpaH | gpaH | sadA | aberrant cytokinesis |
DBS0351566 | sbdS(1-30,TS18,31-274)/ [act15]: eIF(T56K) | eIF6 | sbds | wild type |
DBS0351524 | scrA-/ [act15]: scrA(R177A,R179A,K180A,R183A,R184A,R187A,K190A,K191A,K194A) | scrA | decreased bleb assembly | increased cellular localization | aberrant pseudopodium formation |
DBS0351611 | scrA-/ [act15]: scrA(S287,290,301,335,339,384,388,389,430,432,433,437,440A) | scrA | aberrant pseudopodium formation |
DBS0351522 | scrA-/ [act15]: scrA(S430A,S432A,S433A,S437A,S440A) | scrA | decreased bleb assembly | increased cellular localization | aberrant pseudopodium formation |
DBS0351523 | scrA-/ [act15]: scrA(S430D,S432D,S433D,S437D,S440D) | scrA | decreased pseudopodium size |
DBS0349927 | scrA-/ [act15]: wasA: GFP/ [ act8]: RFP: arcD | scrA | decreased establishment of cell polarity | decreased pseudopodium formation |
DBS0349957 | sma-/ ampA/ [ampA]: ampA | ampA | sma | decreased chemotaxis to folate |
DBS0351063 | sodC-/ [unk]: rasG(C118A) | rasG | sodC | aberrant regulation of GTPase activity |
DBS0350637 | tagB-/ [pkaC]: pkaC | pkaC | tagB | aberrant response to biotic stimulus | abolished spore cell differentiation |
DBS0350698 | tagC-/ [pkaC]: pkaC | pkaC | tagC | development arrests at mound stage | abolished spore cell differentiation |
DBS0236976 | talA- | talA | decreased protein level | decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology |
DBS0304585 | talA-/ [act15]: FLAG: talB | talA | talB | decreased cell-substrate adhesion |
DBS0237616 | talA-/ [act15]: gbpD | gbpD | talA | increased cell-substrate adhesion | aberrant cell morphology | increased pseudopodium formation |
DBS0238395 | talA-/ [act15]: rapA(G12V) | rapA | talA | increased cell-substrate adhesion |
DBS0304582 | talA-/ talB-/ [act15]: FLAG: talB | talA | talB | wild type |
DBS0350713 | talA-/ talB-/ [act15]: talB(K16A) | talA | talB | decreased cell-substrate adhesion |
DBS0304586 | talB-/ [act15]: talA: GFP | talA | talB | aberrant fruiting body morphogenesis |
DBS0350712 | talB-/ [act15]: talB(K16A) | talB | development arrests at tipped mound stage |
DBS0350729 | tipC-/ [unk]: tipC(2725-3848): GFP | tipC | decreased fruiting body size |
DBS0350505 | tpp1-/ [cotB]: tpp1 | tpp1 | wild type |
DBS0302383 | tsuA-/ [unk]: tsuA(1-1774): YFP | tsuA | abolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size |
DBS0302385 | tsuA-/ [unk]: tsuA(1-260): YFP | tsuA | abolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size |
DBS0302384 | tsuA-/ [unk]: tsuA(1774-2247): YFP | tsuA | abolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size |
DBS0302382 | tsuA-/ [unk]: tsuA(K34R): YFP | tsuA | decreased mound size | decreased fruiting body size |
DBS0237033 | vasP-/ [act15]: GFP: vasP(1-264/ 285-380) | vasP | abolished filopodium formation |
DBS0237836 | vasP-/ [act15]: YFP: wipA | vasP | wipA | decreased filopodium formation |
DBS0237842 | vasP-/ [act15]: YFP: wipA/ [act15]: vasP: FLAG | vasP | wipA | increased filopodium formation |
DBS0351313 | vasP-/ [act15]: abpB(129-295) | abpB | vasP | aberrant cellular process |
DBS0351300 | vasP-/ [act15]: eYFP: vasP(S141A) | vasP | decreased protein localization to cell cortex | wild type | decreased lateral pseudopodium retraction | decreased establishment of cell polarity | aberrant actin filament organization |
DBS0351301 | vasP-/ [act15]: eYFP: vasP(S141D) | vasP | aberrant hyperosmotic response | decreased filopodium formation |
DBS0237040 | vasP-/ [act15]: vasP | vasP | decreased filopodium formation |
DBS0237840 | vasP-/ [act15]: vasP | vasP | increased filopodium formation | increased actin filament polymerization |
DBS0237037 | vasP-/ [act15]: vasP(1-110: 231-380) | vasP | aberrant cytokinesis | increased actin filament polymerization | decreased filopodium formation |
DBS0237038 | vasP-/ [act15]: vasP(1-228) | vasP | decreased filopodium formation |
DBS0237039 | vasP-/ [act15]: vasP(111-380) | vasP | increased filopodium formation | increased actin filament polymerization |
DBS0350466 | vasP-/ [unk]: vasP(1-197: 221-380) | vasP | wild type |
DBS0350467 | vasP-/ [unk]: vasP(1-261: 285-380) | vasP | decreased cell motility | abolished filopodium formation |
DBS0350290 | vwkA-/ [act15]: GFP: mhcA | mhcA | vwkA | aberrant myosin II filament organization |
DBS0351509 | wasA-/ [tet]: scrA/ [unk]: GFP: wasA(I173A/ F179A) | scrA | wasA | aberrant pseudopodium formation |
DBS0351508 | wasA-/ [unk]: GFP: wasA(I173A/ F179A) | wasA | aberrant protein localization to trailing edge | decreased establishment of cell polarity |
DBS0237812 | wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA | wasA | increased actin filament polymerization at leading edge |
DBS0237811 | wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA(Y33A/ W39A/ F90A/ F91A) | wasA | decreased actin filament polymerization | decreased actin filament polymerization at leading edge |
DBS0237820 | wasA1-/ [tet]: YFP: wasA2/ [act15]: wipA | wasA | wipA | abolished positive chemotaxis |
DBS0350255 | wasB-/ [act15]: YFP: wasB | wasB | wild type |
DBS0351185 | washc5-/ [act15]: washc5(N457D): GFP | washc5 | abolished exocytosis |
DBS0350247 | wshA-/ fam21-/ [act15]: GFP: wshA | fam21 | wshA | aberrant lysosome organization |
DBS0350944 | xacA-/ [act15]: xacA(1-320) | xacA | decreased growth rate | aberrant cytokinesis |
DBS0350945 | xacA-/ [act15]: xacA(779-1335) | xacA | decreased hypotonic response | aberrant contractile vacuole morphology |
DBS0237091 | yakA-/ [crlA]: crlA | crlA | yakA | abolished vegetative growth |
DBS0349882 | zak2-/ [ecmA]: zakA | zak2 | zakA | precocious prestalk gene expression |
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