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Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains - Null - Overexpression - Multiple - Other - Developmental

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To view more details, including parent strains and references, click on the corresponding dictyBase ID.

Strain ID Strain Descriptor Associated gene(s) Phenotypes
DBS0266719Dd5P4-/ [act15]: Dd5P4: GFPDd5P4wild type
DBS0266695Dd5P4-/ [act15]: GAP5P4Dd5P4decreased growth rate, multiple tips in mound
DBS0266720Dd5P4-/ [act15]: Hs-OCRLDd5P4decreased phagocytosis
DBS0266721Dd5P4-/ [act15]: Hs-OCRL(D422A)Dd5P4decreased phagocytosis
DBS0266694Dd5P4-/ [act15]: cat5P4Dd5P4decreased growth rate, multiple tips in mound
CW0391FLAG-VwkAvwkAaberrant cytokinesis, decreased growth rate in suspension, development arrests at mound stage, increased myosin II assembly, increased protein level
DBS0238036[AS]proA/ proB-/ [act15]: proAproA, proBwild type
DBS0238037[AS]proA/ proB-/ [act15]: proBproA, proBwild type
DBS0238035[AS]proA/ proB-/ [unk]: FLAG: proCproA, proB, proCwild type
DBS0237274[OE]: chlimChLimdecreased growth rate, decreased phagocytosis, increased basal F-actin level
DBS0302602[OE]: disgorgin(Delta-Fbox)/ disgorgin-DDB_G0280955wild type
DBS0302601[OE]: disgorgin(Q551A)/ disgorgin-DDB_G0280955aberrant contractile vacuole organization and biogenesis
DBS0302600[OE]: disgorgin(R515A)/ disgorgin-DDB_G0280955aberrant contractile vacuole organization and biogenesis
DBS0302599[OE]: disgorgin/ disgorgin-DDB_G0280955wild type
DBS0302610[OE]: disgorgin/ phgA-DDB_G0280955, phgAaberrant contractile vacuole organization and biogenesis
JH258[OE]: gpaEgpaEprecocious gene expression, precocious tip formation
DBS0302611[OE]: phgA/ disgorgin-DDB_G0280955, phgAaberrant contractile vacuole organization and biogenesis
DBS0302681[OE]: sgcA(878-2843): GFP/ sgcA-gcA, sgcAdecreased chemotaxis rate
DBS0302682[OE]: sgcA(N1106A): GFP/ gca-/ sgcA-gcA, sgcAaberrant streaming, decreased chemotaxis rate, increased lateral pseudopod formation
DBS0266512[act15]: DDB_G0272656DDB_G0272656wild type
DBS0238107[act15]: FLAG: ppp4Cppp4cwild type
DBS0238108[act15]: FLAG: ppp4C(H113Q)ppp4cdelayed development, development arrests at mound stage
DBS0304572[act15]: GFP: abpD(1441-1736)abpDabolished localization of a protein to the nuclear envelope
DBS0304571[act15]: GFP: abpD(1441-1738)abpDabolished localization of a protein to the nuclear envelope
DBS0304573[act15]: GFP: abpD(1441-1738, 1737P/ A)abpDabolished localization of a protein to the nuclear envelope
DBS0237114[act15]: GFP: abpE(413-481)abpE-1, abpE-2increased lateral pseudopod formation
DBS0235662[act15]: GFP: forH(1-425)forHaberrant protein localization
DBS0304973[act15]: GFP: gefQ(173-651, 818-1298)gefQincreased Ras guanyl-nucleotide exchange factor activity
DBS0304971[act15]: GFP: gefQ(683-833)gefQdecreased Ras guanyl-nucleotide exchange factor activity
DBS0304972[act15]: GFP: gefQ(910-1298)gefQaberrant cytokinesis, aberrant phototaxis
DBS0236070[act15]: GFP: hcpAhcpAaberrant anaphase, decreased growth rate in suspension
DBS0237117[act15]: GFP: krsAkrsAdecreased slug migration
DBS0237118[act15]: GFP: limElimEaberrant cytokinesis
DBS0237122[act15]: GFP: pats1(2087-2351)pats1aberrant cytokinesis
DBS0237123[act15]: GFP: phg2(1-245)phg2decreased phagocytosis
DBS0237702[act15]: GFP: rac1Arac1Aincreased filopodium formation, increased membrane ruffling
DBS0237703[act15]: GFP: rac1Brac1Bincreased filopodium formation, increased membrane ruffling
DBS0237704[act15]: GFP: rac1Crac1Cincreased filopodium formation, increased membrane ruffling
DBS0237125[act15]: GFP: racG(1-168): racH(164-200)racG, racHdecreased chemoattractant-mediated F-actin polymerization, decreased phagocytosis, increased filopodium formation
DBS0237128[act15]: GFP: racH(1-163): racG(167-201)racG, racHdecreased chemoattractant-mediated F-actin polymerization
DBS0237130[act15]: GFP: racH(M13V)racHaberrant cell morphology, aberrant cytokinesis, increased F-actin polymerization
DBS0237132[act15]: GFP: racH(T18N)racHaberrant cell morphology, aberrant cytokinesis
DBS0237133[act15]: GFP: racH: gemA(630-658)gemA, racHdelayed cytokinesis
DBS0238392[act15]: GFP: rapArapAincreased cell-substrate adhesion
DBS0238393[act15]: GFP: rapA(G12V)rapAincreased cell-substrate adhesion
DBS0238394[act15]: GFP: rapA(S17N)rapAdecreased cell-substrate adhesion
DBS0237134[act15]: GFP: sbdssbdswild type
DBS0237135[act15]: GFP: sbdssbdswild type
DBS0304563[act15]: GFP: sun1(283-905)sun1aberrant centrosome localization, aberrant nucleus morphology, aberrant perinuclear space, aberrant sister chromosome segregation, decreased localization of a protein to the nuclear envelope, increased cell size, increased number of centrosomes
DBS0238111[act15]: HA: smkAsmkAdecreased cell polarity, decreased chemotaxis to cAMP, decreased fruiting body size, delayed development
DBS0237817[act15]: YFP: wipAwipAincreased F-actin polymerization at the leading edge, increased filopodium formation
DBS0237819[act15]: YFP: wipA(K36A)wipAincreased F-actin polymerization at the leading edge, increased filopodium formation
DBS0237821[act15]: YFP: wipA(K93A/ S95A)wipAincreased F-actin polymerization at the leading edge, increased filopodium formation
DBS0304574[act15]: abpDabpDabolished localization of a protein to the nuclear envelope
DBS0237096[act15]: abpEabpE-1, abpE-2aberrant aggregation, decreased cell motility, decreased fruiting body size, delayed development, increased lateral pseudopod formation
DBS0238086[act15]: atg1atg1wild type
DBS0238091[act15]: atg1(1-628)atg1wild type
DBS0238088[act15]: atg1(K36A)atg1aberrant cellular response to nitrogen starvation, abolished aggregation, abolished macroautophagy, increased number of autophagosomes
DBS0238090[act15]: atg1(K36A/ 1-628)atg1wild type
DBS0252737[act15]: carA(I104A)carA-1, carA-2decreased cAMP binding
DBS0252732[act15]: carA(I104C)carA-1, carA-2decreased MAP kinase activation
DBS0252740[act15]: carA(I104D)carA-1, carA-2aberrant cAMP wave formation, decreased MAP kinase activation, delayed aggregation, increased cAMP binding
DBS0252744[act15]: carA(I104E)carA-1, carA-2aberrant cAMP wave formation, delayed aggregation, increased cAMP binding
DBS0252741[act15]: carA(I104F)carA-1, carA-2decreased MAP kinase activation, increased cAMP binding
DBS0252738[act15]: carA(I104G)carA-1, carA-2decreased MAP kinase activation, increased cAMP binding
DBS0252747[act15]: carA(I104H)carA-1, carA-2abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0252749[act15]: carA(I104K)carA-1, carA-2abolished aggregation, abolished cAMP wave formation, decreased MAP kinase activation, increased cAMP binding
DBS0252739[act15]: carA(I104L)carA-1, carA-2wild type
DBS0252742[act15]: carA(I104M)carA-1, carA-2increased cAMP binding
DBS0252746[act15]: carA(I104N)carA-1, carA-2abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0252734[act15]: carA(I104P)carA-1, carA-2decreased MAP kinase activation
DBS0252745[act15]: carA(I104Q)carA-1, carA-2abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0252750[act15]: carA(I104R)carA-1, carA-2abolished cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0252743[act15]: carA(I104S)carA-1, carA-2aberrant cAMP wave formation, decreased MAP kinase activation, increased cAMP binding
DBS0252735[act15]: carA(I104T)carA-1, carA-2aberrant cAMP wave formation, increased cAMP binding
DBS0252736[act15]: carA(I104V)carA-1, carA-2wild type
DBS0252733[act15]: carA(I104W)carA-1, carA-2increased cAMP binding
DBS0252748[act15]: carA(I104Y)carA-1, carA-2aberrant cAMP wave formation, decreased MAP kinase activation, development arrests at loose aggregate stage, increased cAMP binding
DBS0302445[act15]: cfaDcfaDaberrant fruiting body morphology, decreased growth rate
DBS0302656[act15]: cnrN/ cnrN-cnrNwild type
DBS0302658[act15]: cnrN/ smlA-cnrN, smlAdecreased fruiting body size
DBS0237102[act15]: cofAcofAincreased actin bundle formation, increased cell motility, increased membrane ruffling
DBS0237104[act15]: dagAdagAwild type
DBS0237106[act15]: dhkC(394-661)dhkCincreased slug migration
DBS0235716[act15]: dhkKdhkKdevelopment arrests at mound stage, precocious aggregation
DBS0235705[act15]: dhkK(D1125N)dhkKaberrant cAMP signaling during aggregation, delayed development
DBS0235707[act15]: dhkK(H825Q)dhkKdecreased fruiting body size, precocious development
DBS0235709[act15]: dhkK(H825Q/ D1125N)dhkKaberrant slug migration, delayed culmination
DBS0237108[act15]: fbxA: FLAGfbxAdecreased prespore cell differentiation
DBS0235979[act15]: fszA: GFPfszAincreased number of tubular mitochondria
DBS0237136[act15]: gpaAgpaAaberrant cytokinesis, aberrant fruiting body morphology, increased stalk length
DBS0252821[act15]: hssAhssAwild type
DBS0237203[act15]: mhkB: FLAGmhkBaberrant cytokinesis, decreased myosin II assembly
DBS0237162[act15]: myc-cdk8cdk8multiple tips
DBS0266839[act15]: myc: ptpΔ(3C649S)ptpCaberrant localization of protein to the nucleus, increased protein tyrosine phosphorylation
DBS0266837[act15]: myc: ptpCptpCaberrant protein localization, aberrant response to hyperosmotic stress, aberrant signal transduction during aggregation
DBS0266838[act15]: myc: ptpC(C649S)ptpCaberrant localization of protein to the nucleus, increased protein tyrosine phosphorylation
DBS0238398[act15]: myc: rapArapAaberrant cell morphology, decreased cell motility, increased cell-substrate adhesion
DBS0238396[act15]: myc: rapA(G12V)rapAdecreased cell motility, delayed aggregation, increased cell-substrate adhesion
DBS0238397[act15]: myc: rapA(S17N)rapAdecreased cell-substrate adhesion
DBS0237167[act15]: myc: rckArckAdelayed development
DBS0237163[act15]: myc: rckA(C551A)rckAdecreased chemotaxis rate, delayed slug formation
DBS0237164[act15]: myc: rckA(E510G)rckAdecreased chemotaxis rate, delayed slug formation
DBS0237165[act15]: myc: rckA(E510G/ N511A)rckAdecreased chemotaxis rate, delayed slug formation
DBS0237166[act15]: myc: rckA(K867A)rckAdecreased chemotaxis rate, delayed slug formation, precocious aggregation
DBS0237179[act15]: myr: rckArckAdecreased chemotaxis rate, delayed development
DBS0237180[act15]: nramp1: GFPnramp1decreased infection rate by Legionella pneumophila, increased iron ion transport
DBS0237182[act15]: pakApakAwild type
DBS0237183[act15]: pakA(K394A)pakAdelayed development, development arrests at mound stage
DBS0237184[act15]: pakA[CA]pakAabolished aggregation
DBS0237185[act15]: pakA[G+K]pakAwild type
DBS0237188[act15]: pkaR(1-497)pkaRdecreased fruiting body size, decreased intracellular cAMP level, precocious development
DBS0235442[act15]: pldB: GFPpldBabolished aggregation
DBS0237192[act15]: rblArblAincreased cell cycle length
SA604[act15]: sgkA: FLAGsgkAaberrant cytokinesis, increased resistance to carboplatin, increased resistance to cisplatin
DBS0238735[act15]: snfA(1-379): GFPsnfAaberrant mitochondrion organization and biogenesis, decreased growth rate, decreased phototaxis, decreased stalk length, increased intracellular ATP level, increased number of mitochondria, increased stalk width
DBS0304457[act15]: sodA/ gcsA-gcsA, sodAwild type
DBS0237194[act15]: sodA: mycsodAabolished aggregation, decreased gene expression
DBS0237195[act15]: spkA: FLAGspkA-1, spkA-2aberrant F-actin organization, aberrant aggregation, decreased cell polarity, decreased chemotaxis rate
AK1209[act15]: tagA(1-890)tagAmultiple tips in mound
DBS0237198[act15]: torAtorAabolished growth
DBS0237199[act15]: trrAtrrAaberrant aggregation, decreased growth rate, decreased phagocytosis, delayed culmination
DBS0237200[act15]: vasPvasPincreased basal F-actin level, increased filopodium formation
DBS0238218[act6]: TAP: GFP: lvsBlvsBwild type
DBS0237205[act6]: dia1dia1delayed aggregation
DBS0236905[act6]: mrps4mrps4precocious aggregation
DBS0235444[act6]: myc: eppA(S250A)eppAdecreased growth rate, decreased intracellular cAMP level, delayed development
DBS0235445[act6]: myc: eppA(S325A)eppAdecreased growth rate
DBS0266836[act6]: ptpBptpBdecreased fruiting body size, delayed aggregation
DBS0304410[act6]: srsAsrsAaberrant fruiting body morphology, decreased gene expression, decreased sporulation, delayed aggregation, increased aggregate size, increased slug size
DBS0304460[act]: alrA/ gcsA-alrA, gcsAwild type
DBS0305081[dscB]: GFP: vamp7A(L35A)vamp7Aincreased localization of protein to the plasma membrane
DBS0304865[expl7]: expl7: GFPexpl7aberrant culminant morphology
DBS0237252[gpaA]: gpaA(G45V)gpaAdelayed development
DBS0237253[gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0236484[pkaC]: pkaCpkaCaberrant fruiting body morphology, decreased intracellular cAMP level, precocious development
DBS0237289[psmC1]: psmC1psmC1aberrant cytokinesis, delayed gene expression, delayed tip formation
DBS0304911[tre]: paxBpaxBaberrant chemotaxis to folate, aberrant endocytosis, abolished sporulation, decreased cell motility, decreased cell-substrate adhesion, development arrests at mound stage, increased cell-cell adhesion
DBS0237938abpC-/ [act15]: GFP: abpC(9-148)abpCaberrant phototaxis
DBS0235426abpC-/ [act15]: abpCabpCwild type
DBS0237945abpC-/ [act15]: abpC(1-348: 449-857): GFPabpCaberrant F-actin organization, aberrant phototaxis
DBS0237946abpC-/ [act15]: abpC(1-556: 644-857): GFPabpCaberrant F-actin organization, aberrant phototaxis
DBS0237941abpC-/ [act15]: abpC(1-739): GFPabpCaberrant phototaxis
DBS0237786acrA-/ [act15]: acgA(1-401)acgA, acrAdecreased gene expression, decreased prespore cell differentiation, decreased sporulation
DBS0235473alrA-/ [act15]: alrAalrAwild type
DBS0235488alxA-/ [act15]: FLAG: alxAalxAdelayed development
DBS0235476alxA-/ [act15]: alxA(1-596): myc2alxAwild type
DBS0235477alxA-/ [act15]: alxA(1-697): myc2alxAwild type
DBS0235478alxA-/ [act15]: alxA(155-697): myc2alxAaberrant fruiting body morphology
DBS0235479alxA-/ [act15]: alxA(293-697): myc2alxAaberrant fruiting body morphology
DBS0235480alxA-/ [act15]: alxA(460-794): myc2alxAaberrant fruiting body morphology
DBS0235481alxA-/ [act15]: alxA(D310A/ N311A)alxAwild type
DBS0235482alxA-/ [act15]: alxA(Q181E/ Q183)alxAwild type
DBS0235483alxA-/ [act15]: alxA(S700A/ S704A/ S708A)alxAwild type
DBS0235484alxA-/ [act15]: alxA(S700D/ S704D/ S708D)alxAwild type
DBS0235485alxA-/ [act15]: alxA(Y315D)alxAwild type
DBS0235486alxA-/ [act15]: alxA(Y315F)alxAwild type
DBS0235487alxA-/ [act15]: alxA: myc2alxAwild type
DBS0235501amtC-/ [act15]: cudAamtC, cudAdelayed culmination
DBS0235502amtC-/ [ecmA]: cudAamtC, cudAdelayed culmination
DBS0235503amtC-/ [pspA]: cudAamtC, cudAdevelopment arrests at slug stage
DBS0305085apm2-/ [dscB]: GFP: vamp7Aapm2, vamp7Aincreased localization of protein to the plasma membrane
DBS0305083apm3-/ [dscB]: GFP: vamp7Aapm3, vamp7Aincreased localization of protein to the plasma membrane
DBS0235510aprA-/ actin15: : aprAaprAaberrant fruiting body morphology, decreased growth rate
DBS0238085atg1-/ [act15]: atg1atg1wild type
DBS0238092atg1-/ [act15]: atg1(1-628)atg1aberrant cellular response to nitrogen starvation, abolished aggregation
DBS0238087atg1-/ [act15]: atg1(K36A)atg1aberrant cellular response to nitrogen starvation, abolished aggregation
DBS0238089atg1-/ [act15]: atg1(K36A/ 1-628)atg1aberrant cellular response to nitrogen starvation, abolished aggregation
DBS0305978atg9-/ [act15]: GFP: atg9atg9wild type
DBS0305979atg9-/ [act15]: atg9: GFPatg9wild type
DBS0302446cfaD-/ [act15]: cfaDcfaDwild type
DBS0302455chcA-/ [act15]: epnA: GFPchcA, epnAaberrant localization of a protein to coated pits
DBS0235604clc-/ [act15]: GFP-clc(146-194)clcaberrant fruiting body morphology, abolished cytokinesis, wild type
DBS0235605clc-/ [act15]: GFP-clc(85-124)clcaberrant fruiting body morphology, abolished cytokinesis, wild type
DBS0235607clc-/ [act15]GFP: clc(1-124)clcaberrant fruiting body morphology, abolished cytokinesis, wild type
DBS0238320cpnA-/ [act15]: GFP: cpnAcpnAdecreased culmination, delayed development, delayed response to hypo-osmotic stress
DBS0266761culB-/ [act15]: pkaCculB, pkaCabolished aggregation, abolished gene expression, abolished sporulation, precocious gene expression
DBS0235712dhkK-/ [act15]: dhkK(D1125N)dhkKaberrant fruiting body morphology
DBS0235719dia1-/ [act6]: trap1dia1, trap1aberrant aggregation, decreased fruiting body size
DBS0235903dimB-/ [act15]: dimA: GFPdimA, dimBabolished localization of protein to the nucleus
DBS0235904dimB-/ [act15]: dimB: GFPdimBwild type
DBS0302607disgorgin-/ [OE]: lvsADDB_G0280955, lvsAaberrant contractile vacuole organization and biogenesis
DBS0302606disgorgin-/ [OE]: lvsDDDB_G0280955, lvsDwild type
DBS0302678disgorgin-/ [OE]: rab8ADDB_G0280955, rab8Aaberrant contractile vacuole organization and biogenesis
DBS0238511drkC-/ [act15]: drkC(1-497): YFPdrkCdecreased phagocytosis
DBS0238513drkC-/ [act15]: drkC(K518R): YFPdrkCdecreased phagocytosis
DBS0238237dstA-/ GFP: dstA(237-707): ORF+dstAabolished culmination, decreased stalk length
DBS0252824dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C2C, dstAaberrant fruiting body morphology
DBS0252823dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 7E7E, dstA, hssBwild type
DBS0252826dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165DDB_G0276165, dstAaberrant fruiting body morphology
DBS0252825dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325DDB_G0282325, dstAaberrant fruiting body morphology
DBS0252816dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssAdstA, hssAwild type
DBS0252822dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssBdstA, hssBwild type
DBS0302598elmoA-/ [act15]: elmoA(1-903/ 959-977): GFPelmoAdecreased cell motility, increased phagocytosis
DBS0302591elmoA-/ [act15]: elmoA: GFPelmoAwild type
DBS0302457epnA-/ [act15]: GFP: epnA(253-677)epnAaberrant spore morphology, abolished localization of protein to coated pits, abolished localization of protein to the plasma membrane
DBS0302456epnA-/ [act15]: epnA(1-133): GFPepnAaberrant localization of a protein to coated pits
DBS0302474epnA-/ [act15]: epnA(R65A/ K78A): GFPepnAaberrant spore morphology, abolished localization of protein to coated pits, abolished localization of protein to the plasma membrane, abolished phosphatidylinositol-4, 5-bisphosphate binding
DBS0302475epnA-/ [act15]: epnA(T107A): GFPepnAaberrant spore morphology
DBS0302454epnA-/ [act15]: epnA: GFPepnAwild type
DBS0235948eppA-/ [act6]: myc: eppAeppAwild type
DBS0304905forC-/ [act15]: GFP-forCforCwild type
DBS0235971forH-/ [act15]: GFP: forHforHdecreased cell motility, increased cell-substrate adhesion, increased filopodium formation
DBS0304440frmA-/ [unk]: GFPfrmAaberrant development, abolished phototaxis, decreased gene expression, delayed development, increased cell-cell adhesion
DBS0305026gabT-[pkaC]: pkaCgabT, pkaCaberrant protein secretion
DBS0304912gbpC-/ [act15]: gbpCgbpCwild type
DBS0304917gbpC-/ [act15]: gbpC(1-1698: 2005-2631)gbpCdecreased chemotaxis to cAMP
DBS0304918gbpC-/ [act15]: gbpC(311-2631)gbpCdecreased chemotaxis to cAMP
DBS0304916gbpC-/ [act15]: gbpC(F1892A)gbpCdecreased chemotaxis to cAMP
DBS0304915gbpC-/ [act15]: gbpC(F2082A/ E2084A/ F2564A/ E2566A)gbpCdecreased chemotaxis to cAMP
DBS0304913gbpC-/ [act15]: gbpC(K342N)gbpCdecreased chemotaxis to cAMP
DBS0304914gbpC-/ [act15]: gbpC(K905W)gbpCdecreased chemotaxis to cAMP
DBS0235998gbpD-/ [act15]: gbpDgbpDaberrant F-actin organization, abolished aggregation, decreased chemotaxis rate, increased cell-substrate adhesion, increased lateral pseudopod formation
DBS0237190gdt1-/ [act15]: pkaR(G135E/ G261A)gdt1, pkaRabolished aggregation, increased gene expression
DBS0304985gefQ-/ [act15]: GFP: gefQ(172-654)gefQabolished Ras guanyl-nucleotide exchange factor activity, decreased phototaxis
DBS0304986gefQ-/ [act15]: GFP: gefQ(910-1298)gefQdecreased phototaxis
DBS0238390gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0238391gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0236092gpaA-/ [gpaA]: gpaA(G45V)gpaAdelayed development
DBS0236093gpaA-/ [gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0236096gpaB-/ [act15]: gpaBgpaBabolished aggregation
DBS0266942gpaB-/ [act15]: gpaBgpaBdelayed aggregation
DBS0266939gpaB-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB, gpaDabolished aggregation
DBS0237137gpaB-/ [act15]: gpaB(D154V)gpaBaberrant aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate
DBS0237138gpaB-/ [act15]: gpaB(E190G)gpaBaberrant aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse
DBS0237139gpaB-/ [act15]: gpaB(I104S)gpaBaberrant aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate
DBS0237140gpaB-/ [act15]: gpaB(L110S)gpaBaberrant aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate
DBS0237141gpaB-/ [act15]: gpaB(L76P)gpaBabolished aggregation
DBS0237142gpaB-/ [act15]: gpaB(N74D)gpaBabolished aggregation, decreased activation of adenylate cyclase, decreased cAMP-induced cAMP pulse, decreased cAMP-induced cGMP pulse, decreased chemotaxis rate
DBS0237143gpaB-/ [act15]: gpaB(R64G)gpaBabolished aggregation, decreased chemotaxis rate
DBS0237144gpaB-/ [act15]: gpaB(S155P)gpaBabolished aggregation, decreased chemotaxis rate
DBS0236097gpaB-/ [gpaA]: gpaBgpaBabolished aggregation
DBS0236099gpaB-/ [gpaB]: gpaBgpaBwild type
DBS0266944gpaD-/ [act15]: gpaBgpaB, gpaDaberrant fruiting body morphology, decreased accumulation of cGMP, decreased chemotaxis to folate
DBS0266946gpaD-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB, gpaDaberrant fruiting body morphology, decreased accumulation of cGMP
DBS0266943gpaD-/ [act15]: gpaDgpaDwild type
DBS0266945gpaD-/ [act15]: gpaEgpaD, gpaEaberrant fruiting body morphology, decreased accumulation of cGMP, decreased chemotaxis to folate
DBS0266947gpaD-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD, gpaEaberrant fruiting body morphology, decreased accumulation of cGMP, decreased chemotaxis to folate
DBS0266941gpaE-/ [act15]: gpaEgpaEprecocious tip formation
DBS0266948gpaE-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD, gpaEprecocious tip formation
DBS0304815grlA-/ [act15]: grlA: GFPgrlAaberrant tip formation
DBS0238866grlJ-/ [act15]: grlJ: GFPgrlJwild type
DBS0238687grpA-/ [act15]: grpA-FLAGgrpAwild type
DBS0236152hcpAΔC-GFPhcpAabolished growth on bacterial plates, decreased growth rate in suspension
DBS0252702icmA-/ [act15]: TAP: YFP: rasGicmA-1, icmA-2, rasGabolished C-terminal protein amino acid methylation
DBS0238521icpA-/ [act15]: GFP: icpA(1-1013)icpAaberrant protein localization
DBS0236493krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238721krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238722krsA-/ [act15]: GFP: krsA(K49R)krsAaberrant streaming
DBS0238723krsA-/ [act15]: GFP: krsA(T173A)krsAabolished streaming
DBS0238725krsA-/ [act15]: GFP: krsA(deltaC)krsAaberrant streaming
DBS0238724krsA-/ [act15]: GFP: krsA(deltaKinase)krsAabolished streaming
DBS0238726krsA-/ [act15]: GFP: krsA(deltaNS)krsAabolished streaming
DBS0238109mekA-/ ppp4C-/ [act15]: FLAG: pppCppp4cdecreased aggregate size, precocious development
DBS0266674mhcA-/ [act15]: GFP: abpC(9-148)abpC, mhcAdecreased pseudopod retraction, decreased uropod retraction
DBS0266675mhcA-/ [act15]: GFP: mhcA(E476K)mhcAdecreased pseudopod retraction
DBS0236548mhcA-/ [act15]: GFP: pats1(2087-2351)mhcA, pats1aberrant cytokinesis
DBS0236549mhcA-/ [act15]: limE(1-145): GFPlimE, mhcAincreased F-actin polymerization
DBS0238158mhcA-/ [act15]: mhcA(81-2116)mhcAdecreased growth rate, development arrests at tipped mound stage
DBS0236550mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)mhcAdecreased filopodium formation
DBS0236551mhcA-/ [act15]: mhcA(T1823D/ T1833D/ T2029D)mhcAincreased filopodium formation
DBS0238157mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R689H)mhcAdecreased actin filament sliding
DBS0236557mhkA-/ [act15]: mhkAmhkAaberrant cytokinesis, decreased growth rate in suspension, decreased myosin II assembly, development arrests at mound stage
DBS0238058mlcE-/ [act15]: myc: mlcEmlcEwild type
DBS0266904mpl1-/ [act15]: flag: mpl1mpl1wild type
DBS0266889myoI-/ [act15]: GFP: myoImyoIwild type
DBS0266890myoI-/ [act15]: GFP: myoI(809-1154)myoIdecreased phagocytosis
DBS0237617myoI-/ [act15]: gbpDgbpD, myoIaberrant cell morphology, increased cell-substrate adhesion, increased pseudopod formation
DBS0236611noxA-/ [act15]: noxA: myc2noxAaberrant fruiting body morphology
DBS0236702nxnA-/ [act15]: GFP: nxnB nxnA, nxnBdevelopment arrests at mound stage
DBS0238362p2xA-/ [act15]: p2xA: GFPp2xAwild type
DBS0236747pefB-/ noxA-/ [act15]: pefBnoxA, pefBaberrant development
DBS0304869phg1A-/ [act15]: phg1a(1-276): phg1b(221-587)phg1a, phg1bdecreased phagocytosis
DBS0304868phg1A-/ [act15]: phg1bphg1a, phg1bdecreased cell-substrate adhesion, decreased phagocytosis, increased secretion of lysosomal enzyme
DBS0304870phg1A-/ [act15]: phg1b(1-220): phg1a(277-642)phg1a, phg1bdecreased phagocytosis
DBS0237615phg2-/ [act15]: gbpDgbpD, phg2aberrant cell morphology, abolished chemotaxis to cAMP, increased pseudopod formation
DBS0267125plc-/ [OE]: dagA(PH): GFP/ [OE]: plcdagA, plcaberrant protein localization, decreased chemotaxis to cAMP, increased CRAC localization to the plasma membrane
DBS0236797pldB-/ [act15]: pldB: GFPpldBabolished aggregation
DBS0236825ppk1-/ [act15]: ppk1ppk1wild type
DBS0238110ppp4C-/ [act15]: smkAppp4c, smkAdelayed development, development arrests at mound stage
DBS0238034proC-/ [unk]: FLAG: proCproCwild type
DBS0302356psrA-/ [act15]: FLAG: gskAgskA, psrAincreased protein kinase activation
DBS0302357psrA-/ [act15]: gskA(K84M/ K85M)gskA, psrAdecreased culmination, decreased gene expression, delayed development
DBS0237191racC-/ [act15]: CFP: racCracCincreased chemoattractant-mediated F-actin polymerization
DBS0237614rasC-/ [act15]: gbpDgbpD, rasCaberrant cell morphology, increased cell-substrate adhesion
DBS0266697rasC-/ rasG-/ [act15]: carAcarA-1, carA-2, rasC, rasGabolished activation of Rap GTPase activity, abolished cAMP-induced cGMP pulse, abolished chemotaxis to cAMP, abolished growth, abolished protein kinase B activation, decreased activation of adenylate cyclase, decreased growth rate
DBS0236859rasD(G12T)rasDdevelopment arrests at mound stage, development arrests at tipped mound stage
DBS0236864rasG-/ [rasG]: rasBrasB, rasGdecreased growth rate in suspension
DBS0235706regA-/ [act15]: dhkK(D1125N)dhkK, regAaberrant fruiting body morphology, precocious development
DBS0236976talA-talAaberrant cell morphology, aberrant cytokinesis, decreased cell-substrate adhesion, decreased phagocytosis
DBS0304585talA-/ [act15]: FLAG: talBtalA, talBdecreased cell-substrate adhesion
DBS0237616talA-/ [act15]: gbpDgbpD, talAaberrant cell morphology, increased cell-substrate adhesion, increased pseudopod formation
DBS0238395talA-/ [act15]: rapA(G12V)rapA, talAincreased cell-substrate adhesion
DBS0304582talA-/ talB-/ [act15]: FLAG: talBtalA, talBwild type
DBS0304586talB-/ [act15]: talA: GFPtalA, talBaberrant fruiting body morphology
DBS0302383tsuA-/ [unk]: tsuA(1-1774): YFPtsuAabolished localization of protein to microtubules, abolished localization of protein to the microtubule organizing center, decreased aggregate size, decreased fruiting body size
DBS0302385tsuA-/ [unk]: tsuA(1-260): YFPtsuAabolished localization of protein to microtubules, abolished localization of protein to the microtubule organizing center, decreased aggregate size, decreased fruiting body size
DBS0302384tsuA-/ [unk]: tsuA(1774-2247): YFPtsuAabolished localization of protein to microtubules, abolished localization of protein to the microtubule organizing center, decreased aggregate size, decreased fruiting body size
DBS0302382tsuA-/ [unk]: tsuA(K34R): YFPtsuAdecreased aggregate size, decreased fruiting body size
DBS0237033vasP-/ [act15]: GFP: vasP(1-264/ 285-380)vasPabolished filopodium formation
DBS0237836vasP-/ [act15]: YFP: wipAvasP, wipAdecreased filopodium formation
DBS0237842vasP-/ [act15]: YFP: wipA/ [act15]: vasP: FLAGvasP, wipAincreased filopodium formation
DBS0237040vasP-/ [act15]: vasPvasPdecreased filopodium formation
DBS0237840vasP-/ [act15]: vasPvasPincreased basal F-actin level, increased filopodium formation
DBS0237037vasP-/ [act15]: vasP(1-110: 231-380)vasPaberrant cytokinesis, decreased filopodium formation, increased basal F-actin level
DBS0237038vasP-/ [act15]: vasP(1-228)vasPdecreased filopodium formation
DBS0237039vasP-/ [act15]: vasP(111-380)vasPincreased basal F-actin level, increased filopodium formation
DBS0237812wasA1-/ [tet]: YFP: wasA2/ [act15]: wasAwasAincreased F-actin polymerization at the leading edge
DBS0237811wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA(Y33A/ W39A/ F90A/ F91A)wasAdecreased F-actin polymerization, decreased F-actin polymerization at the leading edge
DBS0237820wasA1-/ [tet]: YFP: wasA2/ [act15]: wipAwasA, wipAabolished chemotaxis
DBS0237091yakA-/ [crlA]: crlAcrlA, yakAabolished growth

Last updated February 28, 2010

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