Dictyostelium Mutants

Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains - Null - Overexpression - Multiple - Other - Developmental

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Systematic Name Strain Descriptor Associated gene(s) Phenotypes
DBS0350657 [csaA]: csaAcsaAaberrant aggregation | increased calcium-independent cell-cell adhesion
DBS0235594CHE10cbpCdecreased slug migration | precocious aggregation | decreased aggregate size | decreased fruiting body size | delayed culmination
DBS0266719Dd5P4-/ [act15]: Dd5P4: GFPDd5P4wild type
DBS0266695Dd5P4-/ [act15]: GAP5P4Dd5P4decreased growth rate | multiple tips in mound
DBS0266720Dd5P4-/ [act15]: Hs-OCRLDd5P4decreased phagocytosis
DBS0266721Dd5P4-/ [act15]: Hs-OCRL(D422A)Dd5P4decreased phagocytosis
DBS0266694Dd5P4-/ [act15]: cat5P4Dd5P4decreased growth rate | multiple tips in mound
CW0391FLAG-VwkAvwkAincreased myosin II assembly | aberrant response to hypo-osmotic stress | decreased growth rate | aberrant cytokinesis | development arrests at mound stage | increased protein level
CW0368GFP-VwkAvwkAdecreased growth rate | aberrant cytokinesis
DBS0350102GFP: pcppcpaberrant response to hypo-osmotic stress | aberrant contractile vacuole morphology
DBS0236358HR42fbxAabolished culmination | decreased sporulation
DBS0237044VatMpr/ [act15]: vatMvatMwild type
DBS0237042VatMpr/ [act15]: vatM: GFPvatMdecreased growth rate
DBS0238036[AS]proA/ proB-/ [act15]: proAproA | proBwild type
DBS0238037[AS]proA/ proB-/ [act15]: proBproA | proBwild type
DBS0238035[AS]proA/ proB-/ [unk]: FLAG: proCproA | proB | proCwild type
DBS0237274[OE]: chlimChLimincreased basal F-actin level | decreased phagocytosis | decreased growth rate
DBS0350519[OE]: egeAegeAdecreased protein level | abolished aggregation
DBS0237275[OE]: gbfAgbfAprecocious gene expression
JH258[OE]: gpaEgpaEprecocious tip formation | precocious gene expression
DBS0348921[OE]: ipkA1ipkA1aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression
DBS0348922[OE]: itpk1itpk1aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression
DBS0236962[OE]: pdiApdiAdelayed aggregation
DBS0237015[OE]: pdiApdiAaberrant tip formation | abolished slug formation | abolished culmination
DBS0302681[OE]: sgcA(878-2843): GFP/ sgcA-gcA | sgcAaberrant chemotaxis to cAMP | decreased chemotaxis rate
DBS0302682[OE]: sgcA(N1106A): GFP/ gca-/ sgcA-gcA | sgcAaberrant streaming | aberrant chemotaxis to cAMP | increased lateral pseudopod formation | decreased chemotaxis rate
DBS0266621[OE]mipp1mipp1aberrant inositol phosphate metabolic process | aberrant gene expression | increased response to lithium
DBS0349923[RNAi]ctnnA/ [act15]: GFP-mhcActnnAaberrant stalk morphogenesis | aberrant protein localization
DBS0350924[TRE-Pmin]: 6xHis: GFP: dhcA(1384-4725(K1975T))dhcAaberrant molecular function
DBS0350052[TRE-Pmin]: arfA(Q71L): GFParfAaberrant filopodium formation | aberrant cytokinesis
DBS0350053[TRE-Pmin]: arfA(T31N): GFParfAwild type | decreased infection rate by a gram-negative pathogenic bacterium
DBS0350674[act15]: 6xHis: erkAerkAaberrant slug formation
DBS0349845[act15]: 7xHis: myoK: Ty1myoKaberrant cortical actin cytoskeleton stabilization | aberrant engulfment during phagocytosis | aberrant cell morphology
DBS0237100[act15]: CFP: racC(G15V)racCincreased basal F-actin level
DBS0266512[act15]: DDB_G0272656sigN4wild type
DBS0350049[act15]: FLAG: cycCcycCprecocious tip formation
DBS0350321[act15]: FLAG: hbx4hbx4aberrant aggregation | abolished gene expression | abolished slug migration | decreased growth rate | aberrant cytokinesis
DBS0350322[act15]: FLAG: hbx4/ [act15]: cadAcadA | hbx4wild type
DBS0350325[act15]: FLAG: hbx4/ [ecmAO]: lacZhbx4decreased spore viability | aberrant gene expression | increased prestalk cell differentiation
DBS0238107[act15]: FLAG: ppp4Cppp4cwild type
DBS0238108[act15]: FLAG: ppp4C(H113Q)ppp4cdevelopment arrests at mound stage | delayed development
DBS0304572[act15]: GFP: abpD(1441-1736)abpDabolished localization to nuclear envelope
DBS0304571[act15]: GFP: abpD(1441-1738)abpDabolished protein localization to nuclear envelope | abolished localization to nuclear envelope
DBS0304573[act15]: GFP: abpD(1441-1738,1737P/ A)abpDabolished localization to nuclear envelope
DBS0237114[act15]: GFP: abpE(413-481)abpE-1 | abpE-2increased lateral pseudopod formation
DBS0350593[act15]: GFP: cepLcepLdecreased cell polarity | decreased growth rate | decreased phagocytosis | increased cell size | increased cell-substrate adhesion | aberrant centrosome localization
DBS0350594[act15]: GFP: cepL(1-1114)cepLincreased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis
DBS0350595[act15]: GFP: cepL(1-763)cepLincreased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis
DBS0350596[act15]: GFP: cepL(763-1114)cepLdevelopment arrests at loose mound stage | delayed aggregation | increased cell-substrate adhesion | decreased chemotaxis rate | increased growth rate | abolished cell polarity | aberrant phototaxis | delayed gene expression | decreased cell size
DBS0350460[act15]: GFP: docDdocDincreased pseudopod formation | increased F-actin polymerization | increased cell motility
DBS0350288[act15]: GFP: forF(1-1087)forFdecreased pinocytosis | decreased phagocytosis | decreased growth rate
DBS0235662[act15]: GFP: forH(1-425)forHabolished localization to pseudopodium
DBS0350984[act15]: GFP: frmBfrmBaberrant stalk formation | decreased spore size
DBS0304973[act15]: GFP: gefQ(173-651,818-1298)gefQincreased Ras guanyl-nucleotide exchange factor activity
DBS0304971[act15]: GFP: gefQ(683-833)gefQdecreased Ras guanyl-nucleotide exchange factor activity
DBS0304972[act15]: GFP: gefQ(910-1298)gefQaberrant cytokinesis | aberrant phototaxis
DBS0350422[act15]: GFP: gpbBgpbBaberrant vegetative growth | delayed development
DBS0350349[act15]: GFP: gtaC(1-467: 497-587)gtaCabolished localization to nucleus
DBS0350351[act15]: GFP: gtaC(229-587)gtaCabolished localization to cytoplasm
DBS0350359[act15]: GFP: gtaC(281-467: 497-587)gtaCaberrant localization to cytoplasm
DBS0350352[act15]: GFP: gtaC(281-587)gtaCabolished localization to cytoplasm
DBS0350360[act15]: GFP: gtaC(346-467: 497-587)gtaCaberrant cellular localization
DBS0350353[act15]: GFP: gtaC(346-587)gtaCabolished localization to cytoplasm
DBS0350350[act15]: GFP: gtaC(K469,470,494,496A/ R468,471A)gtaCabolished localization to nucleus
DBS0236070[act15]: GFP: hcpAhcpAdecreased growth rate | aberrant anaphase
DBS0237117[act15]: GFP: krsAkrsAdecreased slug migration
DBS0237118[act15]: GFP: limElimEaberrant cytokinesis
DBS0349983[act15]: GFP: lmnBlmnBaberrant chromatin assembly
DBS0350490[act15]: GFP: mhcA(T1823D/ T1833D/ T2029D)/ AX3mhcAdecreased growth rate | aberrant localization
DBS0350852[act15]: GFP: nkaPnkaPaberrant aggregation | decreased gene expression | increased gene expression | aberrant vegetative growth | increased chemotaxis rate
DBS0350338[act15]: GFP: pakApakAincreased phagocytosis
DBS0350337[act15]: GFP: pakA(797-1197)pakAdecreased phagocytosis | decreased cell motility
DBS0237122[act15]: GFP: pats1(2087-2351)pats1aberrant cytokinesis
DBS0237123[act15]: GFP: phg2(1-245)phg2decreased phagocytosis
DBS0235442[act15]: GFP: pldBpldBabolished aggregation
DBS0237702[act15]: GFP: rac1Arac1Aincreased filopodium formation | increased membrane ruffling
DBS0237703[act15]: GFP: rac1Brac1Bincreased filopodium formation | increased membrane ruffling
DBS0237704[act15]: GFP: rac1Crac1Cincreased filopodium formation | increased membrane ruffling
DBS0237125[act15]: GFP: racG(1-168): racH(164-200)racG | racHincreased filopodium formation | decreased chemoattractant-mediated F-actin polymerization | decreased phagocytosis
DBS0237128[act15]: GFP: racH(1-163): racG(167-201)racG | racHdecreased chemoattractant-mediated F-actin polymerization
DBS0237130[act15]: GFP: racH(M13V)racHincreased F-actin polymerization | aberrant cytokinesis | aberrant cell morphology
DBS0237132[act15]: GFP: racH(T18N)racHaberrant cytokinesis | aberrant cell morphology
DBS0237133[act15]: GFP: racH: gemA(630-658)gemA | racHdelayed cytokinesis
DBS0238392[act15]: GFP: rapArapAincreased cell-substrate adhesion
DBS0238393[act15]: GFP: rapA(G12V)rapAincreased cell-substrate adhesion
DBS0238394[act15]: GFP: rapA(S17N)rapAdecreased cell-substrate adhesion
DBS0237134[act15]: GFP: sbdssbdswild type
DBS0237135[act15]: GFP: sbdssbdswild type
DBS0350715[act15]: GFP: src1(2-646)src1aberrant nuclear envelope morphology
DBS0304563[act15]: GFP: sun1(283-905)sun1increased number of centrosomes | decreased protein localization to nuclear envelope | increased cell size | aberrant nucleus morphology | aberrant perinuclear space | aberrant centrosome localization | aberrant sister chromosome segregation
DBS0350441[act15]: GFP: talA/ mhcA-/ talA-mhcA | talAaberrant protein localization
DBS0350648[act15]: HA: Rab14(N121I)rab14decreased pinocytosis | decreased response to hypo-osmotic stress | aberrant contractile vacuole morphology
DBS0350899[act15]: HA: rab11(N126I)rab11Aaberrant contractile vacuole organization and biogenesis | aberrant contractile vacuole morphology
DBS0350812[act15]: HA: rab7A(Q67L)rab7Aincreased exocytosis
DBS0350813[act15]: HA: rab7A(T22N)rab7Adecreased pinocytosis | increased secretion of lysosomal enzyme | decreased exocytosis | decreased phagocytosis | abolished macropinocytosis
DBS0238111[act15]: HA: smkAsmkAdecreased cell polarity | delayed development | decreased fruiting body size | decreased chemotaxis to cAMP
DBS0350429[act15]: RFP: abpEabpE-1 | abpE-2delayed aggregation
DBS0350867[act15]: RFP: mtpnmtpnincreased filopodium formation | decreased protein localization to cell cortex | aberrant F-actin organization | decreased pseudopod size
DBS0350986[act15]: YFP: myoC(G395A)myoCdecreased pinocytosis | decreased phagocytosis | aberrant spindle stabilization
DBS0237817[act15]: YFP: wipAwipAincreased filopodium formation | increased F-actin polymerization at the leading edge
DBS0237819[act15]: YFP: wipA(K36A)wipAincreased filopodium formation | increased F-actin polymerization at the leading edge
DBS0237821[act15]: YFP: wipA(K93A/ S95A)wipAincreased filopodium formation | increased F-actin polymerization at the leading edge
DBS0350673[act15]: abpC: GFPabpCdecreased cell motility
DBS0304574[act15]: abpDabpDabolished protein localization to nuclear envelope
DBS0237096[act15]: abpEabpE-1 | abpE-2aberrant aggregation | increased lateral pseudopod formation | decreased cell motility | delayed development | decreased fruiting body size
DBS0350800[act15]: adprt1Aadprt1Aaberrant cell cycle | decreased growth rate | aberrant response to oxidative stress
DBS0238086[act15]: atg1atg1wild type
DBS0238091[act15]: atg1(1-628)atg1wild type
DBS0238088[act15]: atg1(K36A)atg1abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238090[act15]: atg1(K36A/ 1-628)atg1wild type
DBS0350008[act15]: bzpN: GFPbzpNdecreased growth rate | abolished negative regulation of vegetative growth
JK1[act15]: carAcarA-1 | carA-2delayed aggregation
DBS0252737[act15]: carA(I104A)carA-1 | carA-2decreased cAMP binding
DBS0252732[act15]: carA(I104C)carA-1 | carA-2decreased protein kinase activation
DBS0252740[act15]: carA(I104D)carA-1 | carA-2increased cAMP binding | delayed aggregation | decreased protein kinase activation | aberrant cAMP wave formation
DBS0252744[act15]: carA(I104E)carA-1 | carA-2increased cAMP binding | delayed aggregation | aberrant cAMP wave formation
DBS0252741[act15]: carA(I104F)carA-1 | carA-2increased cAMP binding | decreased protein kinase activation
DBS0252738[act15]: carA(I104G)carA-1 | carA-2increased cAMP binding | decreased protein kinase activation
DBS0252747[act15]: carA(I104H)carA-1 | carA-2development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | abolished cAMP wave formation
DBS0252749[act15]: carA(I104K)carA-1 | carA-2increased cAMP binding | decreased protein kinase activation | abolished aggregation | abolished cAMP wave formation
DBS0252739[act15]: carA(I104L)carA-1 | carA-2wild type
DBS0252742[act15]: carA(I104M)carA-1 | carA-2increased cAMP binding
DBS0252746[act15]: carA(I104N)carA-1 | carA-2development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | abolished cAMP wave formation
DBS0252734[act15]: carA(I104P)carA-1 | carA-2decreased protein kinase activation
DBS0252745[act15]: carA(I104Q)carA-1 | carA-2development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | abolished cAMP wave formation
DBS0252750[act15]: carA(I104R)carA-1 | carA-2development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | abolished cAMP wave formation
DBS0252743[act15]: carA(I104S)carA-1 | carA-2increased cAMP binding | decreased protein kinase activation | aberrant cAMP wave formation
DBS0252735[act15]: carA(I104T)carA-1 | carA-2increased cAMP binding | aberrant cAMP wave formation
DBS0252736[act15]: carA(I104V)carA-1 | carA-2wild type
DBS0252733[act15]: carA(I104W)carA-1 | carA-2increased cAMP binding
DBS0252748[act15]: carA(I104Y)carA-1 | carA-2development arrests at loose mound stage | increased cAMP binding | decreased protein kinase activation | aberrant cAMP wave formation
DBS0302445[act15]: cfaDcfaDdecreased growth rate | aberrant fruiting body morphology
DBS0350333[act15]: cnrF: GFPcnrFaberrant regulation of GTPase activity
DBS0302658[act15]: cnrN: myc/ smlA-cnrN | smlAdecreased fruiting body size
DBS0237102[act15]: cofAcofAincreased actin bundle formation | increased membrane ruffling | increased cell motility
DBS0350583[act15]: csaAcsaAdecreased cell-substrate adhesion | precocious aggregation | increased calcium-independent cell-cell adhesion
DBS0349864[act15]: cyrA: GFPcyrAincreased chemotaxis to cAMP
DBS0237104[act15]: dagAdagAwild type
DBS0350978[act15]: deeJdeeJincreased pinocytosis | increased growth rate | increased phagocytosis
DBS0237106[act15]: dhkC(394-661)dhkCdevelopment arrests at slug stage | increased slug migration
DBS0235716[act15]: dhkKdhkKprecocious aggregation | development arrests at mound stage
DBS0235705[act15]: dhkK(D1125N)dhkKaberrant cAMP signaling during aggregation | delayed development
DBS0235707[act15]: dhkK(H825Q)dhkKprecocious development | decreased fruiting body size
DBS0235709[act15]: dhkK(H825Q/ D1125N)dhkKaberrant slug migration | delayed culmination
DBS0237108[act15]: fbxA: FLAGfbxAdecreased prespore cell differentiation
DBS0350365[act15]: fip(1163-2038)fip-1 | fip-2aberrant prestalk 0 cell differentiation
DBS0350012[act15]: fps: GFPfpsincreased resistance to bisphosphonate
DBS0235979[act15]: fszA: GFPfszAincreased number of tubular mitochondria
DBS0237136[act15]: gpaAgpaAincreased stalk length | aberrant cytokinesis | aberrant fruiting body morphology
DBS0350680[act15]: gpaEgpaEabolished growth | decreased chemotaxis to folate
DBS0237145[act15]: gpaGgpaGaberrant fruiting body morphology
DBS0237146[act15]: gpaHgpaHwild type
DBS0350971[act15]: gpaH/ AX2gpaHaberrant cytokinesis | decreased growth rate | aberrant spore germination | increased cell-substrate adhesion | increased cell-cell adhesion | aberrant development
DBS0350079[act15]: grlBgrlBdelayed aggregation
DBS0350989[act15]: gst4gst4increased fruiting body size
DBS0236152[act15]: hcpA(1-161: 218-225): GFPhcpAdecreased growth rate
DBS0252821[act15]: hssAhssAwild type
DBS0350037[act15]: mekA(299-360)mekAdecreased aggregate size
DBS0350034[act15]: mekA(K321A)mekAdecreased aggregate size
DBS0350033[act15]: mekA(S444A/ T448A)mekAdecreased aggregate size
DBS0237203[act15]: mhkB: FLAGmhkBaberrant cytokinesis | decreased myosin II assembly
DBS0350026[act15]: mip1/ [act15]: mekA: FLAGmekA | mip1-1 | mip1-2aberrant protein localization to nucleus
DBS0350331[act15]: mkpA: GFP: TAPmkpAincreased resistance to cisplatin
DBS0350330[act15]: mkpB: GFP: TAPmkpB-1 | mkpB-2increased resistance to cisplatin
DBS0237162[act15]: myc-cdk8cdk8multiple tips | precocious tip formation
DBS0350050[act15]: myc: cdk8/ [act15]: FLAG: cycCcdk8 | cycCprecocious tip formation
DBS0266837[act15]: myc: ptpCptpCaberrant signal transduction during aggregation | aberrant response to hyperosmotic stress | aberrant protein localization
DBS0350417[act15]: myc: ptpCptpCaberrant protein phosphorylation
DBS0266839[act15]: myc: ptpCΔ(C649S)ptpCaberrant protein localization to nucleus | increased protein tyrosine phosphorylation
DBS0266838[act15]: myc: ptpC(C649S)ptpCaberrant protein localization to nucleus | increased protein tyrosine phosphorylation
DBS0238398[act15]: myc: rapArapAincreased cell-substrate adhesion | decreased cell motility | aberrant cell morphology
DBS0238396[act15]: myc: rapA(G12V)rapAincreased protein localization to cell cortex | delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation
DBS0238397[act15]: myc: rapA(S17N)rapAdecreased cell-substrate adhesion
DBS0237167[act15]: myc: rckArckAdelayed development
DBS0237163[act15]: myc: rckA(C551A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0237164[act15]: myc: rckA(E510G)rckAdelayed slug formation | decreased chemotaxis rate
DBS0237165[act15]: myc: rckA(E510G/ N511A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0237166[act15]: myc: rckA(K867A)rckAdelayed slug formation | precocious aggregation | decreased chemotaxis rate
DBS0350132[act15]: myc: splBsplBincreased protein localization to nucleus | increased protein tyrosine phosphorylation
DBS0351037[act15]: myoE(1-1005)myoEabolished phosphoinositide binding
DBS0351036[act15]: myoE(K859A/ K863A/ R868A/ R869A): GFPmyoEabolished phosphoinositide binding | abolished localization to plasma membrane
DBS0349847[act15]: myoK: MycmyoKdecreased phagocytosis
DBS0237179[act15]: myr: rckArckAdelayed development | decreased chemotaxis rate
DBS0349860[act15]: ndkCndkC-1 | ndkC-2decreased exocytosis | decreased pinocytosis | decreased phagocytosis | decreased growth rate | increased growth rate
DBS0237180[act15]: nramp1: GFPnramp1decreased infection rate by a gram-negative pathogenic bacterium | increased iron ion transport
DBS0350858[act15]: odcodcaberrant cell cycle
DBS0237182[act15]: pakApakAwild type
DBS0237183[act15]: pakA(K394A)pakAdevelopment arrests at mound stage | delayed development
DBS0237184[act15]: pakA[CA]pakAabolished aggregation
DBS0237185[act15]: pakA[G+K]pakAwild type
DBS0349903[act15]: pisApisAdecreased slug migration | aberrant tip formation | delayed aggregation | decreased fruiting body size
DBS0349902[act15]: pisA: GFPpisAdecreased slug migration | increased gene expression | decreased gene expression | delayed aggregation | delayed development | decreased phototaxis
DBS0350693[act15]: pkaCpkaCprecocious development
DBS0237188[act15]: pkaC(1-497)pkaCprecocious development | decreased intracellular cAMP level | decreased fruiting body size
DBS0237189[act15]: pkaR(G135E/ G261A)pkaRdecreased protein tyrosine phosphorylation | decreased cAMP binding | decreased protein kinase activity | abolished aggregation | abolished cAMP-induced cAMP pulse
DBS0350701[act15]: pkaR(G135E/ G261A)/ AX3pkaRdecreased gene expression | abolished cAMP-induced cAMP pulse
DBS0350609[act15]: pkaR(S133T,G135E)pkaRdecreased cAMP binding | decreased protein kinase activity | abolished aggregation | abolished cAMP-induced cAMP pulse
DBS0350920[act15]: pkcApkcAincreased catalytic activity | abolished aggregation
DBS0235538[act15]: pldBpldBdecreased F-actin polymerization | increased catalytic activity | increased exocytosis | aberrant chemotaxis to cAMP | abolished aggregation | decreased sporulation
DBS0349874[act15]: psaA: GFPpsaAaberrant sporulation
DBS0350751[act15]: pten(16-515): GFPptenabolished catalytic activity
DBS0350750[act15]: pten(186-515): GFPptenabolished catalytic activity
DBS0350752[act15]: pten(C124S): GFPptenabolished catalytic activity
DBS0350753[act15]: pten(G129E): GFPptenabolished catalytic activity
DBS0350318[act15]: rab11A: RFPrab11Aaberrant contractile vacuole organization and biogenesis | abolished response to hypo-osmotic stress | decreased contractile vacuole size
DBS0350951[act15]: rac1B(Q61L)rac1Baberrant F-actin organization | increased lateral pseudopod formation | decreased chemotaxis to cAMP
DBS0350952[act15]: rac1B(T17N)rac1Baberrant F-actin organization | delayed aggregation | abolished cell polarity | abolished chemotaxis to cAMP
DBS0350469[act15]: racE(G20V): GFPracEdecreased F-actin polymerization | aberrant cytokinesis | decreased growth rate
DBS0350262[act15]: rbg3rbg3increased lysosome size | decreased growth rate | delayed development
DBS0237192[act15]: rblArblAincreased cell cycle length
DBS0349938[act15]: rgaArgaAaberrant cytokinesis | decreased cell motility | decreased basal F-actin level
DBS0350294[act15]: rheb: YFPrhebincreased cell size
DBS0350890[act15]: rnp1Arnp1Aincreased resistance to nocodazole
DBS0350575[act15]: rps4rps4aberrant aggregation | decreased spore viability | aberrant actin cytoskeleton organization | aberrant vegetative growth | aberrant fruiting body morphology
DBS0236915[act15]: rzpArzpAincreased gene expression | decreased gene expression | delayed culmination
DBS0349793[act15]: sadA(921-952)sadAdecreased cell-substrate adhesion
SA604[act15]: sgkA: FLAGsgkAincreased resistance to cisplatin | aberrant cytokinesis | increased resistance to carboplatin
DBS0238735[act15]: snfA(1-379): GFPsnfAincreased stalk width | increased intracellular ATP level | decreased growth rate | increased number of mitochondria | decreased phototaxis | decreased stalk length | aberrant mitochondrion organization
DBS0350976[act15]: snfA: YFPsnfAdecreased growth rate | aberrant fruiting body morphology
DBS0304457[act15]: sodA/ gcsA-gcsA | sodAwild type
DBS0237194[act15]: sodA: mycsodAdecreased gene expression | abolished aggregation
DBS0237195[act15]: spkA: FLAGspkA-1 | spkA-2aberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
AK1209[act15]: tagA(1-890)tagAmultiple tips in mound
DBS0350962[act15]: tor(212-2380): YFPtordecreased growth rate | aberrant development
DBS0237198[act15]: torAtorAabolished growth
DBS0350862[act15]: tpt1: YFPtpt1decreased growth rate
DBS0237199[act15]: trrAtrrAaberrant aggregation | decreased growth rate | decreased phagocytosis | delayed culmination
DBS0237200[act15]: vasPvasPincreased filopodium formation | increased basal F-actin level
DBS0350911[act6]: GFP: cepA/ cepA(183-346)cepAincreased number of centrosomes
DBS0349984[act6]: GFP: lmnB(1-712)lmnBabolished growth | increased sensitivity to fluid shear stress
DBS0350497[act6]: GFP: rab2Arab2Aaberrant response to hypo-osmotic stress | decreased phagocytosis | increased growth rate
DBS0350499[act6]: GFP: rab2A(Q64L)rab2Adecreased autophagic cell death | aberrant response to hypo-osmotic stress | aberrant cell-cell adhesion | increased growth rate | increased phagocytosis
DBS0306243[act6]: GFP: sun1sun1increased number of centrosomes | aberrant nucleus morphology | aberrant sister chromosome segregation | aberrant centromere complex assembly | aberrant centrosome organization
DBS0306244[act6]: GFP: sun1(1-722)sun1increased number of centrosomes | aberrant nucleus morphology | aberrant sister chromosome segregation | aberrant centromere complex assembly | aberrant centrosome organization
DBS0350685[act6]: csaAcsaAincreased slug size | increased calcium-independent cell-cell adhesion
DBS0237205[act6]: dia1dia1delayed aggregation
DBS0236905[act6]: mrps4mrps4precocious aggregation
DBS0235444[act6]: myc: eppA(S250A)eppAdecreased growth rate | delayed development | decreased intracellular cAMP level
DBS0235445[act6]: myc: eppA(S325A)eppAdecreased growth rate
DBS0266836[act6]: ptpBptpBdelayed aggregation | decreased fruiting body size
DBS0350807[act6]: rabS(N137I): GFPrabSaberrant response to hyperosmotic stress | aberrant response to hypo-osmotic stress
DBS0350806[act6]: rabS: GFPrabSaberrant response to hyperosmotic stress
DBS0350982[act6]: rps6rps6aberrant cytokinesis | delayed development
DBS0304410[act6]: srsAsrsAincreased aggregate size | decreased gene expression | increased slug size | delayed aggregation | decreased sporulation | aberrant fruiting body morphology
DBS0237220[act6]: trap1trap1development arrests at loose mound stage | aberrant aggregation | abolished pinocytosis | increased gene expression | decreased gene expression | decreased growth rate
DBS0350695[act6]: yakAyakAincreased gene expression | abolished growth
DBS0350069[act6]: zizB: GFPzizBaberrant cell separation during cytokinesis | increased filopodium formation
DBS0304460[act]: alrA/ gcsA-alrA | gcsAwild type
DBS0349955[ampA]: RFP: ampAampAdevelopment arrests at mound stage
DBS0350705[cotC]: pkaCpkaCprecocious development | aberrant development | aberrant fruiting body morphology
DBS0350706[cotC]: pkaC/ [spiA]: lacZpkaC | spiAprecocious gene expression
DBS0350048[cycC]: cycC: TAPcycCdecreased protein level
DBS0305081[dscB]: GFP: vamp7A(L35A)vamp7Aincreased localization to plasma membrane
DBS0350820[dscB]: cafAcafAincreased gene expression | precocious development
DBS0237237[dscB]: cycB(106-436)cycBcell cycle arrest
DBS0350922[dscB]: dicA(1-278)dicAincreased cell death | abolished protein binding | aberrant microtubule cytoskeleton organization | aberrant Golgi localization | aberrant sister chromosome segregation | aberrant centrosome organization
DBS0350923[dscB]: dicA(48-654)dicAaberrant microtubule cytoskeleton organization | aberrant Golgi localization | decreased protein binding | aberrant sister chromosome segregation | aberrant centrosome organization
DBS0350589[dscB]: rapArapAdecreased pinocytosis | aberrant F-actin organization | aberrant cell morphology | increased phagocytosis
DBS0350590[dscB]: rapA(G12T)rapAdecreased pinocytosis | increased phagocytosis
DBS0350933[dscC]: kif2kif2aberrant cell cycle
DBS0350703[ecmA]: pkaCpkaCabolished tip formation | development arrests at mound stage
DBS0350659[ecmA]: pkaC(9-648)pkaCdevelopment arrests at tipped mound stage
DBS0350699[ecmA]: pkaR(G135E/ G261A)pkaRdecreased slug size | decreased gene expression | aberrant culminant morphology | delayed tip formation | aberrant slug migration | increased slug migration | aberrant prestalk cell differentiation
DBS0350700[ecmA]: pkaR(G135E/ G261A)/ [ecmB-frag]: lacZpkaRabolished stalk cell differentiation
DBS0350704[ecmB]: pkaCpkaCabolished tip formation | development arrests at mound stage
DBS0350639[ecmF]: expl3: mycexpl3aberrant stalk morphogenesis | delayed slug formation
DBS0304865[expl7]: expl7: GFPexpl7aberrant culminant morphology
DBS0237252[gpaA]: gpaA(G45V)gpaAdelayed development
DBS0237253[gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0349948[ndm]: ndm: RFPndmdevelopment arrests at mound stage
DBS0236086[pdsA-agg]: pdsApdsAprecocious development
DBS0236111[pdsA-ldev]: pdsApdsAdevelopment arrests at mound stage
DBS0236484[pkaC]: pkaCpkaCincreased gene expression | abolished SDF-2 production | decreased intracellular cAMP level | precocious development | precocious gene expression | aberrant fruiting body morphology
DBS0350709[pkaC]: pkaC/ [dscC]: lacZdscC-1 | dscC-2 | pkaCaberrant gene expression
DBS0350696[pkaC]: pkaC/ srfA-pkaC | srfAaberrant spore coat morphology | aberrant gene expression
DBS0237289[psmC1]: psmC1psmC1aberrant cytokinesis | delayed tip formation | delayed gene expression
DBS0350658[pspA]: pkaC(9-648)pkaCprecocious sporulation | aberrant fruiting body morphology
DBS0350697[pspA]: pkaR(G135E/ G261A)pkaRabolished gene expression | decreased gene expression | translucent sorus
DBS0237290[ptpA1]: ptpA1ptpA1-1 | ptpA1-2delayed aggregation | decreased growth rate | aberrant fruiting body morphology
DBS0236867[rasG]: rasG(G12T)rasGaberrant aggregation
DBS0304911[tre]: paxBpaxBabolished sporulation | aberrant endocytosis | decreased cell-substrate adhesion | aberrant chemotaxis to folate | development arrests at mound stage | decreased cell motility | increased cell-cell adhesion
DBS0350267[tre]: secGsecGincreased filopodium formation | aberrant F-actin polymerization | development arrests at mound stage | aberrant actin cytoskeleton organization | abolished cell polarity | abolished chemotaxis to cAMP | delayed gene expression
DBS0350726[unk]: GFP: cepEcepEincreased number of centrosomes | aberrant cytokinesis
DBS0350447[unk]: PTEN(H385G/ N389A/ H390A)ptendecreased localization to plasma membrane | decreased fruiting body size
DBS0350716[unk]: pdsApdsAaberrant development
DBS0350259[unk]: pikA(1-492(S7A/ S11A/ S109A/ S113A/ S177A/ S181A))pikAaberrant localization to plasma membrane
DBS0350837[unk]: rasD(G12T)/ [rasD]: rapArapA | rasDaberrant culmination | decreased prespore cell differentiation | aberrant gene expression | decreased stalk cell differentiation | multiple tips in mound
DBS0350464[unk]: vasP(1-197: 221-261: 285-380)vasPabolished F-actin polymerization
DBS0350463[unk]: vasP(1-261: 285-380)vasPaberrant F-actin organization
DBS0350465[unk]: vasP(1-340: 376-380)vasPdecreased F-actin polymerization | aberrant F-actin organization
DBS0349920aarA-/ [act15]: GFP-mhcAaarAaberrant stalk morphogenesis | aberrant protein localization
DBS0237938abpC-/ [act15]: GFP: abpC(9-148)abpCaberrant phototaxis
DBS0235426abpC-/ [act15]: abpCabpCwild type
DBS0350938abpC-/ [act15]: abpCabpCwild type
DBS0237945abpC-/ [act15]: abpC(1-348: 449-857): GFPabpCaberrant F-actin organization | aberrant phototaxis
DBS0237946abpC-/ [act15]: abpC(1-556: 644-857): GFPabpCaberrant F-actin organization | aberrant phototaxis
DBS0237941abpC-/ [act15]: abpC(1-739): GFPabpCaberrant phototaxis
DBS0349852abpE-/ [act15]: abpEabpE-1 | abpE-2decreased phagocytosis
DBS0350720acaA-/ [acaA-agg]: acaA: mycacaAwild type | decreased gene expression | decreased fruiting body size
DBS0350721acaA-/ [acaA-psp]: acaA: mycacaAdecreased gene expression | decreased aggregate size | decreased fruiting body size
DBS0350722acaA-/ [acaA-pst]: acaA: mycacaAwild type
DBS0350702acaA-/ [act15]: HA: pkaCacaA | pkaCwild type | delayed development | decreased intracellular cAMP level
DBS0350725acaA-/ [act15]: HA: pkaC/ acrA-acaA | acrA | pkaCdecreased gene expression | abolished adenylate cyclase activity | development arrests at tipped mound stage
DBS0350737acaA-/ [act15]: acaAacaAaberrant slug formation
DBS0350738acaA-/ [act15]: acaA(1-390;398-1407)acaAabolished aggregation
DBS0350739acaA-/ [act15]: acaA(L394T/ K482N)acaAwild type
DBS0350735acaA-/ [act15]: pkaR(G135E/ G261A)acaA | pkaRincreased intracellular cAMP level
DBS0350736acaA-/ [unk]: acaA(F306L/ S498G,K504E,E593V,I649T)acaAdecreased gene expression | decreased intracellular cAMP level | abolished cAMP wave formation
DBS0350734acaA-/ [unk]: acaA(N333D,G633S)acaAabolished adenylate cyclase activity
DBS0350733acaA-/ [unk]: acaA(V427I,S642F)acaAabolished activation of adenylate cyclase
DBS0350711acaA-/ [unk]: acgAacaA | acgAaberrant development
DBS0350055acapA-/ [act15]: acapA(R633Q): GFPacapAaberrant filopodium formation | aberrant post-lysosome organization and biogenesis
DBS0350054acapA-/ [act15]: acapA: GFPacapAincreased filopodium formation
DBS0350723acrA-/ [act15]: acaA(L394S)acaA | acrAwild type
DBS0237786acrA-/ [act15]: acgA(1-401)acgA | acrAdecreased gene expression | decreased prespore cell differentiation | decreased sporulation
DBS0350724acrA-/ [pkaC]: pkaCacrA | pkaCdecreased spore viability | decreased fruiting body size | precocious development
DBS0235473alrA-/ [act15]: alrAalrAwild type
DBS0235488alxA-/ [act15]: FLAG: alxAalxAdelayed development
DBS0235476alxA-/ [act15]: alxA(1-596): myc2alxAwild type
DBS0235477alxA-/ [act15]: alxA(1-697): myc2alxAwild type
DBS0235478alxA-/ [act15]: alxA(155-697): myc2alxAaberrant fruiting body morphology
DBS0235479alxA-/ [act15]: alxA(293-697): myc2alxAaberrant fruiting body morphology
DBS0235480alxA-/ [act15]: alxA(460-794): myc2alxAaberrant fruiting body morphology
DBS0235481alxA-/ [act15]: alxA(D310A/ N311A)alxAwild type
DBS0235482alxA-/ [act15]: alxA(Q181E/ Q183)alxAwild type
DBS0235483alxA-/ [act15]: alxA(S700A/ S704A/ S708A)alxAwild type
DBS0235484alxA-/ [act15]: alxA(S700D/ S704D/ S708D)alxAwild type
DBS0235485alxA-/ [act15]: alxA(Y315D)alxAwild type
DBS0235486alxA-/ [act15]: alxA(Y315F)alxAwild type
DBS0235487alxA-/ [act15]: alxA: myc2alxAwild type
DBS0349953ampA/ [ampA]: TAPampAincreased protein secretion | development arrests at mound stage
DBS0235495ampA/ [ampA]: ampAampAincreased pseudopod formation | decreased cell-substrate adhesion | increased pinocytosis | increased F-actin polymerization | aberrant chemotaxis to folate
DBS0349952ampA/ [ampA]: ampA/ lmbd2B-ampA | lmbd2Baberrant chemotaxis
DBS0235501amtC-/ [act15]: cudAamtC | cudAdelayed culmination
DBS0235502amtC-/ [ecmA]: cudAamtC | cudAdelayed culmination
DBS0235503amtC-/ [pspA]: cudAamtC | cudAdevelopment arrests at slug stage
DBS0305085apm2-/ [dscB]: GFP: vamp7Aapm2 | vamp7Aincreased protein localization to plasma membrane
DBS0305083apm3-/ [dscB]: GFP: vamp7Aapm3 | vamp7Aincreased protein localization to plasma membrane
DBS0235510aprA-/ [act15]: aprAaprAdecreased growth rate | aberrant fruiting body morphology
DBS0350009aprA-/ [act15]: bzpN: GFPaprA | bzpNabolished negative regulation of vegetative growth
DBS0238085atg1-/ [act15]: atg1atg1wild type
DBS0238092atg1-/ [act15]: atg1(1-628)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238087atg1-/ [act15]: atg1(K36A)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238089atg1-/ [act15]: atg1(K36A/ 1-628)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0305978atg9-/ [act15]: GFP: atg9atg9wild type
DBS0305979atg9-/ [act15]: atg9: GFPatg9wild type
DBS0350568carA-/ carC-/ [act15]: carA(261-359;S299A,S302G,S303G,S304G,S308A,S324G,S325A,S331A)(369-392;S383A,S385A)carA-1 | carA-2 | carCaberrant F-actin polymerization | aberrant adaptation of adenylate cyclase | aberrant chemotaxis to cAMP | abolished streaming | aberrant cAMP wave formation
DBS0350436cdk8-/ [act15]: myc: cdk8cdk8wild type
DBS0350437cdk8-/ [act15]: myc: cdk8(D194A)cdk8decreased spore viability | abolished aggregation
DBS0306227cenB-/ [act15]: RFP: cenBcenBwild type
DBS0350010cfaD-/ [act15]: bzpN: GFPbzpN | cfaDabolished negative regulation of vegetative growth
DBS0302446cfaD-/ [act15]: cfaDcfaDwild type
DBS0350090chcA-/ [act15]: GFP: ap2a1ap2a1-1 | ap2a1-2 | chcAaberrant protein localization
DBS0302455chcA-/ [act15]: epnA: GFPchcA | epnAaberrant protein localization to coated pits
DBS0350091chcA-/ [act15]: gppA: GFPchcA | gppAaberrant protein localization to plasma membrane
DBS0235604clc-/ [act15]: GFP-clc(146-194)clcabolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235605clc-/ [act15]: GFP-clc(85-124)clcabolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235607clc-/ [act15]GFP: clc(1-124)clcabolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0350474cln3-/ [act15]: GFP: cln3cln3wild type
DBS0350309cnrF-/ [act15]: cnrF: RFPcnrFwild type
DBS0302656cnrN-/ [act15]: cnrNcnrNwild type
DBS0350345corA-/ [act15]: GFP: mhkAcorA | mhkAwild type
DBS0350346corA-/ [act15]: GFP: mhkBcorA | mhkBwild type
DBS0350344corA-/ [act15]: GFP: mhkCcorA | mhkCdecreased catalytic activity | wild type
DBS0350343corA-/ [act15]: GFP: pakA(797-1197)corA | pakAwild type
DBS0350371corA-/ [act15]: corAcorAwild type
DBS0238320cpnA-/ [act15]: GFP: cpnAcpnAdelayed response to hypo-osmotic stress | decreased culmination | delayed development
DBS0349922ctxA-/ [act15]: GFP-mhcActxAaberrant stalk morphogenesis | aberrant tip formation | aberrant protein localization
DBS0350293ctxA-/ ctxB-/ [act15]: GFP: arcAarcA | ctxA | ctxBaberrant protein localization to cell cortex
DBS0349972ctxA-/ ctxB-/ [act15]: acaA: YFPacaA | ctxA | ctxBaberrant fruiting body morphology
DBS0349973ctxA-/ ctxB-/ [act15]: carA: YFPcarA-1 | carA-2 | ctxA | ctxBabolished adenylate cyclase activity | abolished culmination | abolished streaming
DBS0266761culB-/ [act15]: pkaCculB | pkaCabolished gene expression | abolished sporulation | precocious gene expression | abolished aggregation
DBS0349807detA-/ [act6]: GFP: detAdetAwild type
DBS0349816detA-/ [act6]: GFP: detA/ [act6]: 3xHA: culDculD | detAincreased gene expression
DBS0349817detA-/ [act6]: GFP: detA/ [act6]: 3xHA: repEdetA | repEincreased gene expression
DBS0349813detA-/ [cotB]: GFPdetAdecreased prespore cell differentiation
DBS0349811detA-/ [ecm0]: lacZdetAaberrant prestalk 0 cell differentiation
DBS0349812detA-/ [ecmA0]: GFPdetAincreased prestalk cell differentiation
DBS0349808detA-/ [ecmA0]: lacZdetAincreased prestalk cell differentiation
DBS0349809detA-/ [ecmA]: lacZdetAincreased prestalk A cell differentiation
DBS0349810detA-/ [ecmB]: lacZdetAdelayed development
DBS0350394dgat1-/ dgat2-/ [act15]: GFP: dgat2dgat1 | dgat2wild type
DBS0235703dhkA-/ [pkaC]: pkaCdhkA | pkaCaberrant stalk morphogenesis
DBS0235712dhkK-/ [act15]: dhkK(D1125N)dhkKaberrant fruiting body morphology
DBS0235719dia1-/ [act6]: trap1dia1 | trap1aberrant aggregation | decreased fruiting body size
DBS0235903dimB-/ [act15]: dimA: GFPdimA | dimBabolished protein localization to nucleus
DBS0235904dimB-/ [act15]: dimB: GFPdimBwild type
DBS0349975dmtA-/ [dimB]: dimBdimB | dmtAdecreased prestalk B cell differentiation
DBS0238511drkC-/ [act15]: drkC(1-497): YFPdrkCdecreased phagocytosis
DBS0238513drkC-/ [act15]: drkC(K518R): YFPdrkCdecreased phagocytosis
DBS0350218drnB-/ [act15]: pre-miRNAdrnBabolished microRNA processing
DBS0350210drnB-/ [act6]: lacZ/ [RNAi]lacZdrnBabolished production of siRNA involved in RNA interference | abolished transitive RNA interference
DBS0302602dsgg-/ OE]: dsgg(Delta-Fbox)dsggwild type
DBS0302606dsgg-/ [OE]: GFP: lvsDdsgg | lvsDwild type
DBS0302599dsgg-/ [OE]: dsggdsggwild type
DBS0302601dsgg-/ [OE]: dsgg(Q551A)dsggaberrant contractile vacuole organization and biogenesis
DBS0302600dsgg-/ [OE]: dsggR515A)dsggaberrant contractile vacuole organization and biogenesis
DBS0302607dsgg-/ [OE]: lvsAdsgg | lvsAaberrant contractile vacuole organization and biogenesis
DBS0302611dsgg-/ [OE]: phgAdsgg | phgAaberrant contractile vacuole organization and biogenesis
DBS0302678dsgg-/ [OE]: rab8Adsgg | rab8Aaberrant contractile vacuole organization and biogenesis
DBS0238237dstA-/ GFP: dstA(237-707): ORF+dstAabolished culmination | decreased stalk length
DBS0252824dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C2C | dstAaberrant fruiting body morphology
DBS0252823dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 7E7E | dstA | hssBwild type
DBS0252826dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165DDB_G0276165 | dstAaberrant fruiting body morphology
DBS0252825dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325DDB_G0282325 | dstAaberrant fruiting body morphology
DBS0252816dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssAdstA | hssAwild type
DBS0252822dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssBdstA | hssBwild type
DBS0350804ehd-/ [act15]: dymA: GFPdymA | ehdaberrant phagosome maturation | decreased phagosomal proteolysis
DBS0302598elmoA-/ [act15]: elmoA(1-903/ 959-977): GFPelmoAdecreased cell motility | increased phagocytosis
DBS0302591elmoA-/ [act15]: elmoA: GFPelmoAwild type
DBS0302457epnA-/ [act15]: GFP: epnA(253-677)epnAaberrant spore morphology | abolished localization to coated pits | abolished localization to plasma membrane
DBS0302456epnA-/ [act15]: epnA(1-133): GFPepnAaberrant localization to coated pits
DBS0302474epnA-/ [act15]: epnA(R65A/ K78A): GFPepnAaberrant spore morphology | abolished localization to coated pits | abolished localization to plasma membrane | abolished phosphatidylinositol-4,5-bisphosphate binding | abolished protein localization to plasma membrane | abolished protein phosphorylation
DBS0302475epnA-/ [act15]: epnA(T107A): GFPepnAaberrant spore morphology | abolished protein localization to plasma membrane
DBS0302454epnA-/ [act15]: epnA: GFPepnAwild type
DBS0235948eppA-/ [act6]: myc: eppAeppAwild type
DBS0350681erkA-/ [act15]: gpaEerkA | gpaEwild type
DBS0304905forC-/ [act15]: GFP: forCforCwild type
DBS0235971forH-/ [act15]: GFP: forHforHincreased filopodium formation | decreased cell motility | increased cell-substrate adhesion
DBS0304440frmA-/ [unk]: GFPfrmAdecreased gene expression | increased cell-cell adhesion | delayed development | aberrant development | abolished phototaxis
DBS0305026gabT-[pkaC]: pkaCgabT | pkaCaberrant protein secretion
DBS0304912gbpC-/ [act15]: gbpCgbpCwild type
DBS0304917gbpC-/ [act15]: gbpC(1-1698: 2005-2631)gbpCdecreased chemotaxis to cAMP
DBS0349868gbpC-/ [act15]: gbpC(1-2331: 2470-2631): GFPgbpCaberrant streaming | decreased chemotaxis to cAMP
DBS0304918gbpC-/ [act15]: gbpC(311-2631)gbpCdecreased chemotaxis to cAMP
DBS0304916gbpC-/ [act15]: gbpC(F1892A)gbpCdecreased chemotaxis to cAMP
DBS0304915gbpC-/ [act15]: gbpC(F2082A/ E2084A/ F2564A/ E2566A)gbpCdecreased chemotaxis to cAMP
DBS0304913gbpC-/ [act15]: gbpC(K342N)gbpCdecreased chemotaxis to cAMP
DBS0304914gbpC-/ [act15]: gbpC(K905W)gbpCdecreased chemotaxis to cAMP
DBS0235998gbpD-/ [act15]: gbpDgbpDaberrant F-actin organization | increased cell-substrate adhesion | increased lateral pseudopod formation | decreased chemotaxis rate | abolished aggregation
DBS0350387gcsA-/ [act15]: carAcarA-1 | carA-2 | gcsAaberrant initiation of development
DBS0350388gcsA-/ [act15]: yakAgcsA | yakAwild type
DBS0237190gdt1-/ [act15]: pkaR(G135E/ G261A)gdt1 | pkaRincreased gene expression | abolished aggregation
DBS0350449gefA-/ dscB]: rasG(S17N)gefA | rasGdecreased chemoattractant-mediated F-actin polymerization | decreased positive regulation of GTPase activity | aberrant chemotaxis to cAMP | decreased protein kinase activation
DBS0304985gefQ-/ [act15]: GFP: gefQ(172-654)gefQabolished Ras guanyl-nucleotide exchange factor activity | decreased phototaxis
DBS0304986gefQ-/ [act15]: GFP: gefQ(910-1298)gefQdecreased phototaxis
DBS0238390gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0238391gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0236092gpaA-/ [gpaA]: gpaA(G45V)gpaAdelayed development
DBS0236093gpaA-/ [gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0236096gpaB-/ [act15]: gpaBgpaBabolished aggregation
DBS0266942gpaB-/ [act15]: gpaBgpaBdelayed aggregation
DBS0266939gpaB-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB | gpaDabolished aggregation
DBS0237137gpaB-/ [act15]: gpaB(D154V)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237138gpaB-/ [act15]: gpaB(E190G)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased cAMP-induced cAMP pulse
DBS0237139gpaB-/ [act15]: gpaB(I104S)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237140gpaB-/ [act15]: gpaB(L110S)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237141gpaB-/ [act15]: gpaB(L76P)gpaBabolished aggregation
DBS0237142gpaB-/ [act15]: gpaB(N74D)gpaBdecreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | abolished aggregation | decreased cAMP-induced cAMP pulse
DBS0237143gpaB-/ [act15]: gpaB(R64G)gpaBdecreased chemotaxis rate | abolished aggregation
DBS0237144gpaB-/ [act15]: gpaB(S155P)gpaBdecreased chemotaxis rate | abolished aggregation
DBS0236097gpaB-/ [gpaA]: gpaBgpaBabolished aggregation
DBS0236099gpaB-/ [gpaB]: gpaBgpaBwild type
DBS0266944gpaD-/ [act15]: gpaBgpaB | gpaDdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266946gpaD-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB | gpaDdecreased accumulation of cGMP | aberrant fruiting body morphology
DBS0266943gpaD-/ [act15]: gpaDgpaDwild type
DBS0266945gpaD-/ [act15]: gpaEgpaD | gpaEdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266947gpaD-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD | gpaEdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266941gpaE-/ [act15]: gpaEgpaEprecocious tip formation
DBS0266948gpaE-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD | gpaEprecocious tip formation
DBS0350678gpaE-/ [act15]: gpaE(K10E/ K11E)gpaEdelayed tip formation | delayed gene expression
LW14gpbA-/ [OE]: carAcarA-1 | carA-2 | gpbAdecreased protein kinase activation
DBS0350470gpbA-/ [act15]: GFP: capcap | gpbAdecreased phagocytosis
HO547gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: CFP: FKBP/ [act15]: limE(1-145): GFPgpbAaberrant cortical actin cytoskeleton organization
HO543gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: YFP: FKBPgpbAabolished chemotaxis to folate | decreased electrotaxis
DBS0350479gpr89-/ [act15]: gpr89: GFPgpr89wild type
DBS0304815grlA-/ [act15]: grlA: GFPgrlAaberrant tip formation
DBS0238866grlJ-/ [act15]: grlJ: GFPgrlJwild type
DBS0350284grlJ-/ [act15]: grlJ: GFPgrlJwild type
DBS0238687grpA-/ [act15]: grpA-FLAGgrpAwild type
DBS0349930gskA-/ [act15]: GFP: tacAgskA | tacAincreased protein localization to nucleus
DBS0349881gskA-/ [act15]: gskA(Y214F)gskAabolished streaming
DBS0350260gskA-/ [unk]: pikA(1-492(S7D/ S11D/ S109D/ S113D/ S177D/ S181D))gskA | pikAwild type
DBS0350348gtaC-/ [act15]: GFP: gtaCgtaCwild type
DBS0350357gtaC-/ [act15]: GFP: gtaC(C500,503,522,525S)gtaCaberrant gene expression | abolished aggregation | decreased fruiting body size
DBS0350358gtaC-/ [act15]: GFP: gtaC(T376A/ S379,380A/ C500,503,522,525S)gtaCaberrant localization to nucleus
DBS0350361gtaC-/ [act15]: gtaC: (468-496): GFP: gtaCgtaCdevelopment arrests at mound stage | decreased aggregate size | precocious development
DBS0350257gxcC-/ [act15]: GFP: gxcCgxcCwild type
DBS0350269gxcT-/ [act15]: GFP: gxcTgxcTwild type
DBS0350656hatA-/ [hatB]: hatBhatA | hatBaberrant cellular response to stress
DBS0350289hspc300-/ [act15]: myc: hspc300hspc300wild type
DBS0252702icmA-/ [act15]: TAP: YFP: rasGicmA-1 | icmA-2 | rasGabolished C-terminal protein amino acid methylation
DBS0238521icpA-/ [act15]: GFP: icpA(1-1013)icpAaberrant protein localization
DBS0350439iplA-/ [act15]: GFP: iplAiplAwild type
DBS0350959kif10-/ [act15]: dhcA(1384-4725)dhcA | kif10wild type
DBS0350022kif5-/ [act15]: FLAG: kif5kif5aberrant cytokinesis | aberrant cell morphology
DBS0350023kif5-/ [act15]: FLAG: kif5(342-990)kif5aberrant cell morphology
DBS0350024kif5-/ [act15]: GFP: kif5(805-990)kif5aberrant cytokinesis
DBS0350947kif8-/ [act15]: dhcA(1384-4725)dhcA | kif8wild type
DBS0350044kil2-/ [act15]: kil1kil1 | kil2abolished resistance to a pathogenic bacterium
DBS0236493krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238721krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238722krsA-/ [act15]: GFP: krsA(K49R)krsAaberrant streaming
DBS0238723krsA-/ [act15]: GFP: krsA(T173A)krsAabolished streaming
DBS0238725krsA-/ [act15]: GFP: krsA(deltaC)krsAaberrant streaming
DBS0238724krsA-/ [act15]: GFP: krsA(deltaKinase)krsAabolished streaming
DBS0238726krsA-/ [act15]: GFP: krsA(deltaNS)krsAabolished streaming
DBS0350537ku80-/ myc: ku80(1-782)ku80decreased DNA mediated transformation
DBS0350453lpten-/ [act15]: lpten: RFPlptenwild type
DBS0350036mekA-/ [act15]: mekA(299-360)mekAdecreased aggregate size
DBS0350035mekA-/ [act15]: mekA(K321A)mekAdecreased aggregate size
DBS0350032mekA-/ [act15]: mekA(S444A/ T448A)mekAdecreased aggregate size
DBS0238109mekA-/ ppp4C-/ [act15]: FLAG: pppCppp4cdecreased aggregate size | precocious development
DBS0266674mhcA-/ [act15]: GFP: abpC(9-148)abpC | mhcAdecreased uropod retraction | decreased pseudopod retraction
DBS0266675mhcA-/ [act15]: GFP: mhcA(E476K)mhcAdecreased pseudopod retraction
DBS0350489mhcA-/ [act15]: GFP: mhcA/ [RNAi]rmd1mhcA | rmd1aberrant protein localization
DBS0236548mhcA-/ [act15]: GFP: pats1(2087-2351)mhcA | pats1aberrant cytokinesis
DBS0350291mhcA-/ [act15]: gppA: GFPgppA | mhcAaberrant contractile vacuole morphology | decreased contractile vacuole discharge
DBS0236549mhcA-/ [act15]: limE(1-145): GFPlimE | mhcAincreased F-actin polymerization
DBS0350808mhcA-/ [act15]: mhcA(1-933: 1455-2116]mhcAwild type | aberrant cytokinesis | aberrant fruiting body morphology
DBS0238158mhcA-/ [act15]: mhcA(81-2116)mhcAdecreased growth rate | development arrests at tipped mound stage
DBS0236550mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)mhcAdecreased filopodium formation
DBS0236551mhcA-/ [act15]: mhcA(T1823D/ T1833D/ T2029D)mhcAincreased filopodium formation
DBS0350948mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(E683K)mhcAaberrant catalytic activity
DBS0350949mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R686C)mhcAaberrant catalytic activity
DBS0238157mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R689H)mhcAdecreased actin filament sliding
DBS0236557mhkA-/ [act15]: mhkAmhkAdecreased growth rate | development arrests at mound stage | aberrant cytokinesis | decreased myosin II assembly
DBS0238058mlcE-/ [act15]: myc: mlcEmlcEwild type
DBS0349919mlkA-/ [act15]: GFP-mhcAmlkAaberrant stalk morphogenesis
DBS0266904mpl1-/ [act15]: flag: mpl1mpl1wild type
DBS0350391mrfA-/ [act15]: myc: mrfA(K772A): FLAGmrfAaberrant protein modification
DBS0350390mrfA-/ [act15]: myc: mrfA(S767A): FLAGmrfAaberrant protein modification | delayed development
DBS0350389mrfA-/ [act15]: myc: mrfA: FLAGmrfAwild type
DBS0350990myoA-/ myoB-/ [act15]: myoBmyoA | myoBdelayed aggregation
DBS0350991myoA-/ myoB-/ [act15]: myoB(1-1052)myoA | myoBdecreased pinocytosis | aberrant F-actin organization | decreased growth rate
DBS0350992myoA-/ myoB-/ [act15]: myoB(S332)myoA | myoBdecreased pinocytosis | aberrant F-actin organization | decreased growth rate
DBS0266889myoI-/ [act15]: GFP: myoImyoIwild type
DBS0266890myoI-/ [act15]: GFP: myoI(809-1154)myoIdecreased phagocytosis
DBS0237617myoI-/ [act15]: gbpDgbpD | myoIincreased pseudopod formation | increased cell-substrate adhesion | aberrant cell morphology
DBS0349846myoK-/ [act15]: YFP: myoK(1-121: 262-858)myoKdecreased phagocytosis
DBS0349850myoK-/ [act15]: myoKmyoKincreased phagocytosis
DBS0349854myoK-/ [act15]: pakB(1-337: 563-852)myoK | pakBwild type
DBS0349841nhe1-/ [act15]: mhcA: GFPmhcA | nhe1aberrant protein localization
DBS0236611noxA-/ [act15]: noxA: myc2noxAaberrant fruiting body morphology
DBS0350196nsfA(A1854T, T1984A, C2131A, A2398T, T2574A)nsfA | pkaCabolished SDF production
DBS0236702nxnA-/ [act15]: GFP: nxnB nxnA | nxnBdevelopment arrests at mound stage
DBS0238362p2xA-/ [act15]: p2xA: GFPp2xAwild type
DBS0350014pah-/ [act15]: 6xHis: pahpahwild type
DBS0350016pah-/ [act15]: 6xHis: pah(92-415)pahabolished growth
DBS0350015pah-/ [act15]: 6xHis: pah(92-441)pahwild type
DBS0350810pakA-/ [act15]: pakA(T579A)pakAdecreased chemotaxis to cAMP
DBS0349889pakA-/ [act15]: pakA: GFPpakAwild type
DBS0350428pakB-/ [act15]: RFP: abpEabpE-1 | abpE-2 | pakBaberrant establishment and/ or maintenance of cell polarity | decreased chemotaxis to cAMP | abolished aggregation | aberrant protein localization
DBS0350430pakB-/ [act15]: RFP: abpE/ [act15]: GFP: pak(1-180)abpE-1 | abpE-2 | pakBwild type
DBS0350282pakD-/ [act15]: pakDpakDdevelopment arrests at mound stage
DBS0350395pakD-/ [act15]: pakD: GFPpakDwild type
DBS0350973paxB-/ [act15]: gpaHgpaH | paxBaberrant cytokinesis
DBS0350094paxB-/ [act15]: pldBpaxB | pldBwild type | increased phagocytosis
DBS0350893pdeD-/ pdeE-/ [unk]: pdeEpdeD | pdeEdelayed aggregation
DBS0236747pefB-/ noxA-/ [act15]: pefBnoxA | pefBaberrant development
DBS0304869phg1A-/ [act15]: phg1A(1-276): phg1B221-587)phg1A | phg1Bdecreased phagocytosis
DBS0304868phg1A-/ [act15]: phg1Bphg1A | phg1Bincreased secretion of lysosomal enzyme | wild type | decreased cell-substrate adhesion | aberrant protein level | decreased phagocytosis
DBS0304870phg1A-/ [act15]: phg1B(1-220): phg1a(277-642)phg1A | phg1Bdecreased phagocytosis
DBS0237615phg2-/ [act15]: gbpDgbpD | phg2increased pseudopod formation | aberrant cell morphology | abolished chemotaxis to cAMP
DBS0302610phgA-/ [OE]: dsggdsgg | phgAaberrant contractile vacuole organization and biogenesis
DBS0350471pikA-/ pikB-/ [act15]: GFP: capcap | pikA | pikBwild type
DBS0350708pkaC-/ [act6]: pkaC(303-648)pkaCwild type
DBS0350707pkaC-/ [act6]: pkaC(330-648)pkaCabolished aggregation
DBS0350919pkcA-/ [act15]: pldBpkcA | pldBaberrant aggregation | decreased sporulation
DBS0267125plc-/ [OE]: dagA(PH): GFP/ [OE]: plcdagA | plcincreased CRAC localization to the plasma membrane | decreased chemotaxis to cAMP | aberrant protein localization
DBS0350047plc-/ [act15]: pten: GFPplc | ptenwild type | aberrant protein localization to cytoplasm
DBS0236797pldB-/ [act15]: pldB: GFPpldBabolished aggregation
DBS0236825ppk1-/ [act15]: ppk1ppk1wild type
DBS0238110ppp4C-/ [act15]: smkAppp4c | smkAdevelopment arrests at mound stage | delayed development
DBS0238034proC-/ [unk]: FLAG: proCproCwild type
DBS0350305psenA-/ psenB-/ [act15]: GFP: psenBpsenA | psenBwild type
DBS0350306psenA-/ psenB-/ [act15]: psenB(D348A/ D394A)psenA | psenBwild type
DBS0302356psrA-/ [act15]: FLAG: gskAgskA | psrAincreased protein kinase activation
DBS0302357psrA-/ [act15]: gskA(K84M/ K85M)gskA | psrAdecreased culmination | decreased gene expression | delayed development | increased protein kinase activation
DBS0350829psrA-/ [unk]: FLAG: rasD(G12T)psrA | rasDincreased protein kinase activation
DBS0350454pten-/ [act15]: lpten: RFPlpten | ptenwild type
DBS0349890pten-/ [act15]: pakA: GFPpakA | ptenaberrant cytokinesis
DBS0350754pten-/ [act15]: pten(186-515): GFPptendecreased chemotaxis to cAMP | aberrant development
DBS0350755pten-/ [act15]: pten(C124S): GFPptendecreased chemotaxis to cAMP | aberrant development
DBS0236831pten-/ [act15]: pten: GFPptenwild type
DBS0349893pten-/ pakA-/ [act15]: pakA(T585A): GFPpakA | ptendecreased chemotaxis to cAMP
DBS0349900pten-/ pakA-/ [act15]: pakA(T585E): GFPpakA | ptenaberrant cytokinesis | decreased chemotaxis to cAMP
DBS0349899pten-/ pakA-/ [act15]: pakA: GFPpakA | ptenaberrant cytokinesis
DBS0350675ptpB-/ [act15]: 6xHis: erkAerkA | ptpBaberrant streaming
DBS0350018qdpr-/ [act15]: pahpah | qdprdecreased growth rate
DBS0350011qkgA-/ [act15]: bzpN: GFPbzpN | qkgA-1 | qkgA-2abolished negative regulation of vegetative growth
DBS0237191racC-/ [act15]: CFP: racCracCincreased chemoattractant-mediated F-actin polymerization
DBS0349949racE-/ [act15]: fttBfttB | racEdecreased growth rate
DBS0349946racE-/ [act15]: fttB: GFPfttB | racEabolished protein localization to cell cortex
DBS0350956racE-/ [act15]racE(G20V)racEwild type
DBS0350957racE-/ [act15]racE(T25N)racEabolished cytokinesis
DBS0350317rapgap9-/ [act15]: GFP: rapgap9rapgap9wild type
DBS0237614rasC-/ [act15]: gbpDgbpD | rasCincreased cell-substrate adhesion | aberrant cell morphology
DBS0350740rasC-/ [rasC]: rasGrasC | rasGabolished activation of adenylate cyclase | abolished aggregation
DBS0350742rasC-/ [rasC]: rasG(1-77(D30A)): rasC(79-189)rasC | rasGwild type
DBS0350741rasC-/ [rasC]: rasG(D30A)rasC | rasGaberrant aggregation | decreased activation of adenylate cyclase
DBS0266697rasC-/ rasG-/ [act15]: carAcarA-1 | carA-2 | rasC | rasGabolished growth | abolished activation of GTPase activity | decreased growth rate | decreased activation of adenylate cyclase | abolished protein kinase activation | abolished cAMP-induced cGMP pulse | abolished chemotaxis to cAMP
DBS0350480rasC-/ rasG-/ [rasG]: rasDrasC | rasD | rasGdecreased chemotaxis to folate
DBS0350482rasC-/ rasG-/ [rasG]: rasD(1-104): rasG(103-189)rasC | rasD | rasGdecreased chemotaxis to folate
DBS0350481rasC-/ rasG-/ [rasG]: rasGrasC | rasGwild type
DBS0350483rasC-/ rasG-/ [rasG]: rasG(1-104): rasD(103-187)rasC | rasD | rasGwild type
DBS0236859rasD(G12T)rasDdevelopment arrests at mound stage | development arrests at tipped mound stage
DBS0236864rasG-/ [OE]: rasBrasB | rasGdecreased growth rate
DBS0350448rasG-/ [dscB]: rasG(S17N)rasGdecreased chemoattractant-mediated F-actin polymerization | decreased positive regulation of GTPase activity | decreased protein kinase activation | decreased chemotaxis to cAMP
DBS0349996rblA-/ [act15]: GFP/ [act15]: myc: btgbtg | rblAincreased sorting to prestalk region
DBS0235706regA-/ [act15]: dhkK(D1125N)dhkK | regAprecocious development | aberrant fruiting body morphology
DBS0349921rgaA-/ [act15]: GFP-mhcArgaAaberrant stalk morphogenesis | aberrant tip formation | aberrant protein localization
DBS0350020rgfA-/ [act15]: rgfArgfAdecreased chemotaxis to folate | delayed development
DBS0350193ric8-/ [act15]: GFP: ric8ric8wild type
DBS0350219rrpC-/ [act15]: pre-miRNArrpCincreased microRNA processing
DBS0350974sadA-/ [act15]: gpaHgpaH | sadAaberrant cytokinesis
DBS0349927scrA-/ [act15]: wasA: GFP/ [ act8]: RFP: arcDscrAdecreased cell polarity | decreased pseudopod formation
DBS0349957sma-/ ampA/ [ampA]: ampAampA | smadecreased chemotaxis to folate
DBS0350637tagB-/ [pkaC]: pkaCpkaC | tagBabolished SDF-1 production | aberrant response to SDF-1
DBS0350698tagC-/ [pkaC]: pkaCpkaC | tagCdevelopment arrests at mound stage | abolished SDF-2 production
DBS0236976talA-talAdecreased protein level | decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology
DBS0304585talA-/ [act15]: FLAG: talBtalA | talBdecreased cell-substrate adhesion
DBS0237616talA-/ [act15]: gbpDgbpD | talAincreased pseudopod formation | increased cell-substrate adhesion | aberrant cell morphology
DBS0238395talA-/ [act15]: rapA(G12V)rapA | talAincreased cell-substrate adhesion
DBS0304582talA-/ talB-/ [act15]: FLAG: talBtalA | talBwild type
DBS0350713talA-/ talB-/ [act15]: talB(K16A)talA | talBdecreased cell-substrate adhesion
DBS0304586talB-/ [act15]: talA: GFPtalA | talBaberrant fruiting body morphology
DBS0350712talB-/ [act15]: talB(K16A)talBdevelopment arrests at tipped mound stage
DBS0350729tipC-/ [unk]: tipC(2725-3848): GFPtipCdecreased fruiting body size
DBS0350505tpp1-/ [cotB]: tpp1tpp1wild type
DBS0302383tsuA-/ [unk]: tsuA(1-1774): YFPtsuAabolished localization to microtubules | decreased aggregate size | abolished localization to microtubule organizing center | decreased fruiting body size
DBS0302385tsuA-/ [unk]: tsuA(1-260): YFPtsuAabolished localization to microtubules | abolished localization to microtubule organizing center | decreased aggregate size | decreased fruiting body size
DBS0302384tsuA-/ [unk]: tsuA(1774-2247): YFPtsuAabolished localization to microtubules | abolished localization to microtubule organizing center | decreased aggregate size | decreased fruiting body size
DBS0302382tsuA-/ [unk]: tsuA(K34R): YFPtsuAdecreased aggregate size | decreased fruiting body size
DBS0237033vasP-/ [act15]: GFP: vasP(1-264/ 285-380)vasPabolished filopodium formation
DBS0237836vasP-/ [act15]: YFP: wipAvasP | wipAdecreased filopodium formation
DBS0237842vasP-/ [act15]: YFP: wipA/ [act15]: vasP: FLAGvasP | wipAincreased filopodium formation
DBS0237040vasP-/ [act15]: vasPvasPdecreased filopodium formation
DBS0237840vasP-/ [act15]: vasPvasPincreased filopodium formation | increased basal F-actin level
DBS0237037vasP-/ [act15]: vasP(1-110: 231-380)vasPincreased basal F-actin level | aberrant cytokinesis | decreased filopodium formation
DBS0237038vasP-/ [act15]: vasP(1-228)vasPdecreased filopodium formation
DBS0237039vasP-/ [act15]: vasP(111-380)vasPincreased filopodium formation | increased basal F-actin level
DBS0350466vasP-/ [unk]: vasP(1-197: 221-380)vasPwild type
DBS0350467vasP-/ [unk]: vasP(1-261: 285-380)vasPdecreased cell motility | abolished filopodium formation
DBS0350290vwkA-/ [act15]: GFP: mhcAmhcA | vwkAaberrant myosin II organization
DBS0237812wasA1-/ [tet]: YFP: wasA2/ [act15]: wasAwasAincreased F-actin polymerization at the leading edge
DBS0237811wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA(Y33A/ W39A/ F90A/ F91A)wasAdecreased F-actin polymerization | decreased F-actin polymerization at the leading edge
DBS0237820wasA1-/ [tet]: YFP: wasA2/ [act15]: wipAwasA | wipAabolished positive chemotaxis
DBS0350255wasB-/ [act15]: YFP: wasBwasBwild type
DBS0350247wshA-/ fam21-/ [act15]: GFP: wshAfam21 | wshAaberrant post-lysosome organization and biogenesis
DBS0350944xacA-/ [act15]: xacA(1-320)xacAdecreased growth rate | aberrant cytokinesis
DBS0350945xacA-/ [act15]: xacA(779-1335)xacAdecreased response to hypo-osmotic stress | aberrant contractile vacuole morphology
DBS0237091yakA-/ [crlA]: crlAcrlA | yakAabolished growth
DBS0349882zak2-/ [ecmA]: zakAzak2 | zakAaberrant gene expression

Last updated October 28, 2017

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